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Overview

ID MAG04064
Name TLS3_bin.53
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Polyangia
Order Polyangiales
Family Polyangiaceae
Genus JANYGI01
Species
Assembly information
Completeness (%) 84.14
Contamination (%) 3.14
GC content (%) 69.0
N50 (bp) 18,791
Genome size (bp) 9,064,591

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes5988

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1037830_0 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0 1596.0
TLS3_k127_1037830_1 Non-ribosomal peptide synthetase modules and related proteins K04780 - - 0.0 1486.0
TLS3_k127_1037830_2 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000001889 209.0
TLS3_k127_1037830_3 Cyclic nucleotide-monophosphate binding domain K07001 - - 0.00000000000000000000000000000000001555 159.0
TLS3_k127_1037830_4 PhoQ Sensor - - - 0.000000000000000003523 87.0
TLS3_k127_1047075_0 extracellular polysaccharide biosynthetic process K06994,K16554,K16692 - - 1.238e-239 769.0
TLS3_k127_1047075_1 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 323.0
TLS3_k127_1047129_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 525.0
TLS3_k127_1047129_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 328.0
TLS3_k127_1047129_2 Heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008307 230.0
TLS3_k127_1047129_3 - - - - 0.0000000000000000000000002827 113.0
TLS3_k127_1047129_5 - - - - 0.00000000000003623 80.0
TLS3_k127_1056120_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 523.0
TLS3_k127_1056120_3 Protein of unknown function (DUF1698) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 378.0
TLS3_k127_1056120_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 346.0
TLS3_k127_1056120_5 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002049 255.0
TLS3_k127_1056120_6 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000005814 118.0
TLS3_k127_106207_0 AMP-binding enzyme C-terminal domain - - - 0.0 1073.0
TLS3_k127_107356_0 type IV pilus secretin PilQ K02666 - - 0.0 1071.0
TLS3_k127_107356_1 pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 605.0
TLS3_k127_107356_2 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 326.0
TLS3_k127_107356_3 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 313.0
TLS3_k127_107356_4 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000142 273.0
TLS3_k127_107356_5 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000000000000000000000000000000000000008961 229.0
TLS3_k127_1074182_0 Diguanylate cyclase - - - 0.0 1040.0
TLS3_k127_1074182_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 539.0
TLS3_k127_1074182_2 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 516.0
TLS3_k127_1074182_3 WHG domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001634 244.0
TLS3_k127_1074182_4 protein conserved in cyanobacteria - - - 0.0000000000001616 85.0
TLS3_k127_1074182_5 protein conserved in cyanobacteria - - - 0.000001351 52.0
TLS3_k127_1081016_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1727.0
TLS3_k127_1081016_1 Sulfatase K01133 - 3.1.6.6 4.478e-286 910.0
TLS3_k127_1081016_10 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000001876 224.0
TLS3_k127_1081016_11 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000003447 170.0
TLS3_k127_1081016_12 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000003075 160.0
TLS3_k127_1081016_13 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000006719 144.0
TLS3_k127_1081016_14 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000001566 62.0
TLS3_k127_1081016_15 Outer membrane efflux protein - - - 0.000003097 59.0
TLS3_k127_1081016_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 2.865e-196 621.0
TLS3_k127_1081016_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 497.0
TLS3_k127_1081016_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 445.0
TLS3_k127_1081016_5 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 416.0
TLS3_k127_1081016_6 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 307.0
TLS3_k127_1081016_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 306.0
TLS3_k127_1081016_9 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001306 255.0
TLS3_k127_1109284_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 514.0
TLS3_k127_1109284_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 475.0
TLS3_k127_1110980_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 620.0
TLS3_k127_1110980_1 DNA-binding response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 583.0
TLS3_k127_1110980_10 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003755 273.0
TLS3_k127_1110980_11 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005463 269.0
TLS3_k127_1110980_12 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000001018 256.0
TLS3_k127_1110980_13 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006153 263.0
TLS3_k127_1110980_14 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000003318 244.0
TLS3_k127_1110980_15 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000008089 228.0
TLS3_k127_1110980_16 Domain of unknown function (DUF4398) - - - 0.0000000000000000000000000000000000000000000000000000000000007843 221.0
TLS3_k127_1110980_17 - - - - 0.000000000000000000000000000000000000000000000000000000871 199.0
TLS3_k127_1110980_18 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000001314 195.0
TLS3_k127_1110980_2 protein kinase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 416.0
TLS3_k127_1110980_20 Evidence 4 Homologs of previously reported genes of K09700 - - 0.0000000000000000000000000000000004892 138.0
TLS3_k127_1110980_21 Transglycosylase associated protein - - - 0.00000000000000000000000000000001826 131.0
TLS3_k127_1110980_23 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000693 120.0
TLS3_k127_1110980_25 chaperone-mediated protein folding - - - 0.0000000000000000000000000052 130.0
TLS3_k127_1110980_26 Protein of unknown function (DUF4230) - - - 0.000000000000000000002494 103.0
TLS3_k127_1110980_27 Histidine kinase - - - 0.000000000000000000002584 105.0
TLS3_k127_1110980_29 Domain of unknown function (DUF2383) - - - 0.000000000000000008327 92.0
TLS3_k127_1110980_3 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 400.0
TLS3_k127_1110980_30 Domain of unknown function (DUF4398) - - - 0.00000000000005816 78.0
TLS3_k127_1110980_33 Belongs to the ompA family K03286 - - 0.000000232 53.0
TLS3_k127_1110980_34 serine threonine protein kinase K15923 - 3.2.1.51 0.000005234 54.0
TLS3_k127_1110980_35 COG1309 Transcriptional regulator - - - 0.00001261 49.0
TLS3_k127_1110980_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 388.0
TLS3_k127_1110980_5 Inositol monophosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 356.0
TLS3_k127_1110980_6 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 361.0
TLS3_k127_1110980_7 Encapsulating protein for peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 352.0
TLS3_k127_1110980_8 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 301.0
TLS3_k127_1110980_9 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002064 282.0
TLS3_k127_1112521_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 478.0
TLS3_k127_1112521_1 Family membership K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 358.0
TLS3_k127_1122320_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 2.102e-226 708.0
TLS3_k127_1122320_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 2.089e-196 617.0
TLS3_k127_1122320_2 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 544.0
TLS3_k127_1122320_3 antisigma factor binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 452.0
TLS3_k127_1122320_4 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 415.0
TLS3_k127_1122320_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000001748 211.0
TLS3_k127_1136466_0 PFAM Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 444.0
TLS3_k127_1136466_1 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 448.0
TLS3_k127_1136466_2 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 434.0
TLS3_k127_1149365_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 543.0
TLS3_k127_1149365_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 334.0
TLS3_k127_117715_0 SNF2 family N-terminal domain - - - 2.193e-272 875.0
TLS3_k127_117715_1 Phage tail protein (Tail_P2_I) - - - 4.448e-244 784.0
TLS3_k127_117715_10 phosphoglycolate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 340.0
TLS3_k127_117715_11 Rhs Element Vgr Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 340.0
TLS3_k127_117715_12 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 291.0
TLS3_k127_117715_13 Flagellar Assembly Protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 286.0
TLS3_k127_117715_14 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001322 276.0
TLS3_k127_117715_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001413 292.0
TLS3_k127_117715_16 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004432 294.0
TLS3_k127_117715_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002064 264.0
TLS3_k127_117715_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008057 263.0
TLS3_k127_117715_19 Putative transposase, YhgA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000001288 242.0
TLS3_k127_117715_2 Baseplate J-like protein - - - 2.102e-239 769.0
TLS3_k127_117715_20 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000003195 218.0
TLS3_k127_117715_21 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000000008155 236.0
TLS3_k127_117715_22 - - - - 0.00000000000000000000000000000000000000000000000000006159 206.0
TLS3_k127_117715_23 GPW gp25 family protein K06903 - - 0.000000000000000000000000000000000000000000000001073 179.0
TLS3_k127_117715_24 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000001906 168.0
TLS3_k127_117715_25 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000003229 178.0
TLS3_k127_117715_26 - - - - 0.0000000000000000000000000000000000000000352 174.0
TLS3_k127_117715_27 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000004931 173.0
TLS3_k127_117715_28 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001968 152.0
TLS3_k127_117715_3 Phage tail sheath C-terminal domain K06907 - - 3.271e-235 744.0
TLS3_k127_117715_30 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.000002841 50.0
TLS3_k127_117715_4 AAA C-terminal domain K07478 - - 5.792e-228 725.0
TLS3_k127_117715_5 Phage tail sheath protein subtilisin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 621.0
TLS3_k127_117715_7 Phage late control gene D protein (GPD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 409.0
TLS3_k127_117715_8 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 408.0
TLS3_k127_117715_9 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 353.0
TLS3_k127_1180798_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 0.0 1135.0
TLS3_k127_1180798_1 oligosaccharyl transferase activity - - - 2.433e-243 782.0
TLS3_k127_1180798_11 Protein of unknown function (DUF533) K11962 - - 0.000000000000000000000000000000000000005951 156.0
TLS3_k127_1180798_13 Sel1-like repeats. K07126 - - 0.000007018 59.0
TLS3_k127_1180798_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 408.0
TLS3_k127_1180798_3 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 390.0
TLS3_k127_1180798_4 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 394.0
TLS3_k127_1180798_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 357.0
TLS3_k127_1180798_6 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007171 270.0
TLS3_k127_1180798_7 double-stranded DNA endodeoxyribonuclease activity K02411 - - 0.00000000000000000000000000000000000000000000000000000000000000000000207 241.0
TLS3_k127_1180798_8 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000002533 219.0
TLS3_k127_1180798_9 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000007256 195.0
TLS3_k127_1197474_0 polyketide synthase - - - 0.0 1716.0
TLS3_k127_1197474_1 polyketide synthase - - - 0.0 1508.0
TLS3_k127_1197474_2 PKS_DH K15314 - - 0.0 1490.0
TLS3_k127_1197474_3 synthase K16398,K16417,K20788 - - 0.0 1412.0
TLS3_k127_1197474_4 PKS_DH K15641 - - 0.0 1215.0
TLS3_k127_1197474_5 synthase - - - 7.219e-288 919.0
TLS3_k127_1197474_6 PFAM Enoyl-CoA hydratase isomerase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000002678 196.0
TLS3_k127_1197474_7 PFAM Hydroxymethylglutaryl-coenzyme A synthase K01641,K15311 - 2.3.3.10 0.00000000000000000000000000000000000000000000001289 192.0
TLS3_k127_120865_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 462.0
TLS3_k127_120865_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 460.0
TLS3_k127_120865_10 Transposase domain (DUF772) - - - 0.00006318 45.0
TLS3_k127_120865_11 DNA binding domain, excisionase family - - - 0.0001428 52.0
TLS3_k127_120865_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 343.0
TLS3_k127_120865_3 Dienelactone hydrolase K22249 - 3.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 317.0
TLS3_k127_120865_4 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002281 281.0
TLS3_k127_120865_5 Caspase domain - - - 0.00000000000000000000000000000000000000000001336 174.0
TLS3_k127_120865_6 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000002493 169.0
TLS3_k127_120865_8 trisaccharide binding - - - 0.000000000000005155 86.0
TLS3_k127_120865_9 Belongs to the 'phage' integrase family - - - 0.000000006834 68.0
TLS3_k127_121015_0 Cell division protein FtsI penicillin-binding protein 2 - - - 7.345e-208 664.0
TLS3_k127_121015_1 AcrB/AcrD/AcrF family - - - 1.238e-204 679.0
TLS3_k127_121015_2 Response regulator receiver K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 421.0
TLS3_k127_121015_3 Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 305.0
TLS3_k127_121015_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000001392 158.0
TLS3_k127_121015_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000001394 113.0
TLS3_k127_121015_7 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00006116 55.0
TLS3_k127_1240982_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0 1184.0
TLS3_k127_1240982_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 1.71e-204 660.0
TLS3_k127_1240982_2 - - - - 0.00000000000000000000000000000000000000000000000000000000009473 209.0
TLS3_k127_1240982_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000003503 212.0
TLS3_k127_1249537_0 type VI secretion protein K11900 - - 1.477e-251 791.0
TLS3_k127_1249537_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 2.093e-243 765.0
TLS3_k127_1249537_2 homoserine dehydrogenase K00003 - 1.1.1.3 4.561e-194 616.0
TLS3_k127_1249537_3 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 490.0
TLS3_k127_1249537_4 Protein of unknown function (DUF1553) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 472.0
TLS3_k127_1261281_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 4.247e-216 679.0
TLS3_k127_1261281_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 490.0
TLS3_k127_1261281_2 Protease prsW family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 381.0
TLS3_k127_1261281_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000005952 180.0
TLS3_k127_1273435_0 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 424.0
TLS3_k127_1273435_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 370.0
TLS3_k127_1273435_2 antisigma factor binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002326 266.0
TLS3_k127_1273435_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000231 138.0
TLS3_k127_1273435_4 gluconolactonase activity - - - 0.0000000000004505 81.0
TLS3_k127_1281237_0 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006718 487.0
TLS3_k127_1281237_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 336.0
TLS3_k127_1281237_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 312.0
TLS3_k127_1281237_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000009128 199.0
TLS3_k127_1282940_0 Carboxypeptidase regulatory-like domain - - - 0.0 1174.0
TLS3_k127_1282940_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 612.0
TLS3_k127_1282940_10 Tellurite resistance protein TerB - - - 0.00001415 57.0
TLS3_k127_1282940_2 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 426.0
TLS3_k127_1282940_3 - - - - 0.0000000000000000000000000000000423 126.0
TLS3_k127_1282940_4 - - - - 0.0000000000000000000000000005119 121.0
TLS3_k127_1282940_6 phosphorelay signal transduction system - - - 0.00000000000000000000000003856 121.0
TLS3_k127_1282940_7 Plasmid stabilization system K19092 - - 0.00000000000000000000004446 102.0
TLS3_k127_1282940_8 positive regulation of growth K07746 - - 0.000000000000000008685 85.0
TLS3_k127_1282940_9 - - - - 0.000002223 59.0
TLS3_k127_1294176_0 von Willebrand factor (vWF) type A domain K11912 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 574.0
TLS3_k127_1294176_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 337.0
TLS3_k127_1294176_2 Rare lipoprotein A (RlpA)-like double-psi beta-barrel K20628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005551 260.0
TLS3_k127_1294176_3 Lipase (class 3) K01046 - 3.1.1.3 0.0000000000000000000000000000000000000000000000000000000000007532 225.0
TLS3_k127_1294176_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000905 161.0
TLS3_k127_1294176_6 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000003525 98.0
TLS3_k127_1294176_7 Alpha-1,2-mannosidase - - - 0.00001303 50.0
TLS3_k127_1295656_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1294.0
TLS3_k127_1295656_1 Protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 582.0
TLS3_k127_1295656_2 Collagen-binding surface adhesin SpaP (antigen I II family) K07337 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 293.0
TLS3_k127_1295656_3 - - - - 0.000000000000000000000000000000000000000002402 169.0
TLS3_k127_1295656_4 Psort location Cytoplasmic, score - - - 0.0000000000000000002788 94.0
TLS3_k127_1296853_0 Efflux ABC transporter, permease ATP-binding protein K06147 - - 5.982e-251 786.0
TLS3_k127_1296853_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 3.369e-223 703.0
TLS3_k127_1296853_10 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000001524 131.0
TLS3_k127_1296853_11 Mannan-binding protein - - - 0.0000000000000009066 80.0
TLS3_k127_1296853_2 negative regulation of DNA recombination K07456 - - 6.275e-219 696.0
TLS3_k127_1296853_3 SERine Proteinase INhibitors K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 472.0
TLS3_k127_1296853_5 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 320.0
TLS3_k127_1296853_6 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008267 272.0
TLS3_k127_1296853_7 Dolichol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001841 239.0
TLS3_k127_1296853_9 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000006118 217.0
TLS3_k127_1297269_0 signal peptide peptidase SppA, 36K type K04773 - - 8.142e-309 969.0
TLS3_k127_1297269_1 Sigma-54 dependent transcriptional regulator K14414 - - 4.415e-245 766.0
TLS3_k127_1297269_13 Phage integrase family - - - 0.0000000000000000000135 108.0
TLS3_k127_1297269_2 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 532.0
TLS3_k127_1297269_3 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 504.0
TLS3_k127_1297269_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 482.0
TLS3_k127_1297269_5 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 374.0
TLS3_k127_1297269_6 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 310.0
TLS3_k127_1297269_7 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 295.0
TLS3_k127_1297269_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000003183 190.0
TLS3_k127_1298986_0 Zinc finger, swim domain protein - - - 1.108e-227 731.0
TLS3_k127_1298986_1 Peptidase family M13 K07386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 598.0
TLS3_k127_1298986_2 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 592.0
TLS3_k127_1298986_3 lyase activity K03497 - - 0.000000000000000000000000000000000000000000000000000000000001591 227.0
TLS3_k127_131279_0 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 4.423e-263 822.0
TLS3_k127_131279_1 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 493.0
TLS3_k127_131279_11 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000146 55.0
TLS3_k127_131279_2 ABC transporter, ATP-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 435.0
TLS3_k127_131279_3 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 313.0
TLS3_k127_131279_5 STAS domain K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 302.0
TLS3_k127_131279_7 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001161 251.0
TLS3_k127_131279_8 HYR domain - - - 0.0000000000000000000000000000000000000000000000000000003639 213.0
TLS3_k127_131279_9 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000005697 156.0
TLS3_k127_1325718_0 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 0.0 1125.0
TLS3_k127_1325718_1 Domain of unknown function (DUF3488) - - - 0.0 1024.0
TLS3_k127_1325718_10 - - - - 0.00000000000000000000000009283 123.0
TLS3_k127_1325718_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 565.0
TLS3_k127_1325718_3 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 558.0
TLS3_k127_1325718_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 533.0
TLS3_k127_1325718_5 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 443.0
TLS3_k127_1325718_6 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 352.0
TLS3_k127_1325718_7 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 306.0
TLS3_k127_1325718_9 - - - - 0.0000000000000000000000000000000000000000000000000000007001 208.0
TLS3_k127_1328377_0 Sulfatase-modifying factor enzyme 1 - - - 5.658e-268 850.0
TLS3_k127_1328377_1 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K00830,K03430 - 2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 574.0
TLS3_k127_1328377_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 473.0
TLS3_k127_1328377_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 370.0
TLS3_k127_1334133_0 Acyl transferase domain - - - 0.0 1317.0
TLS3_k127_1334133_1 protein conserved in bacteria - - - 9.261e-317 990.0
TLS3_k127_1334133_10 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000000000000000000000000000005455 192.0
TLS3_k127_1334133_11 cell envelope organization K05807,K08309 - - 0.000000000000000000000000000000000000000000002077 178.0
TLS3_k127_1334133_2 Rhs_assc_core RHS repeat-associated core domain protein - - - 3.509e-289 948.0
TLS3_k127_1334133_3 2-nitropropane dioxygenase - - - 3.138e-209 666.0
TLS3_k127_1334133_4 methyltransferase activity K00213,K00222 - 1.3.1.21,1.3.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 441.0
TLS3_k127_1334133_5 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 437.0
TLS3_k127_1334133_6 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 401.0
TLS3_k127_1334133_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 384.0
TLS3_k127_1334133_8 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 380.0
TLS3_k127_1334133_9 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 293.0
TLS3_k127_135387_0 Sulfatase - - - 1.243e-300 934.0
TLS3_k127_135387_1 NAT, N-acetyltransferase, of N-acetylglutamate synthase K12659,K22478 - 1.2.1.38,2.3.1.1,2.7.2.8 5.214e-208 665.0
TLS3_k127_135387_10 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001394 282.0
TLS3_k127_135387_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003043 254.0
TLS3_k127_135387_13 STAS domain K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000001405 239.0
TLS3_k127_135387_14 DNA-binding regulatory protein K03088 - - 0.00000000000000000000000000000000000000000000000004317 192.0
TLS3_k127_135387_15 exodeoxyribonuclease I activity K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000006741 146.0
TLS3_k127_135387_16 antisigma factor binding - - - 0.0000000000000000000000000000000005986 141.0
TLS3_k127_135387_19 pyrroloquinoline quinone binding - - - 0.000000000006165 78.0
TLS3_k127_135387_2 Belongs to the ATCase OTCase family K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 582.0
TLS3_k127_135387_20 B-1 B cell differentiation - - - 0.0000003299 59.0
TLS3_k127_135387_3 Arginosuccinate synthase K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 574.0
TLS3_k127_135387_4 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 533.0
TLS3_k127_135387_5 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 494.0
TLS3_k127_135387_6 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 421.0
TLS3_k127_135387_7 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 418.0
TLS3_k127_135387_8 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 355.0
TLS3_k127_135387_9 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 297.0
TLS3_k127_136436_0 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 576.0
TLS3_k127_136436_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 492.0
TLS3_k127_136436_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 365.0
TLS3_k127_136436_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001175 267.0
TLS3_k127_136436_4 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002254 242.0
TLS3_k127_136436_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000001655 246.0
TLS3_k127_136436_6 PFAM Protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000006994 180.0
TLS3_k127_136436_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000003172 166.0
TLS3_k127_136436_9 HNH endonuclease - - - 0.000005019 51.0
TLS3_k127_1377746_0 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 1.672e-221 694.0
TLS3_k127_1377746_1 - - - - 2.537e-207 661.0
TLS3_k127_1377746_2 ubiquinol oxidase subunit I K00425 - 1.10.3.14 1.132e-204 644.0
TLS3_k127_1377746_3 oxidase, subunit K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 461.0
TLS3_k127_1377746_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 419.0
TLS3_k127_1377746_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 377.0
TLS3_k127_1377746_6 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005784 276.0
TLS3_k127_1377746_7 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 K04041 - 3.1.3.11 0.000000000000001142 78.0
TLS3_k127_1382069_0 Sulfatase-modifying factor enzyme 1 - - - 0.0 1235.0
TLS3_k127_1382069_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 577.0
TLS3_k127_1382069_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K08651,K13274,K14645,K20486 - 3.4.21.66 0.0000000000000000000000000000000000000000002691 179.0
TLS3_k127_1382069_3 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000000000000000000002548 163.0
TLS3_k127_1382069_4 - - - - 0.00001622 55.0
TLS3_k127_1384531_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1007.0
TLS3_k127_1384531_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 595.0
TLS3_k127_1384531_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 375.0
TLS3_k127_1384531_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 316.0
TLS3_k127_1384531_4 Preprotein translocase subunit K03210 - - 0.000000000000000000000004287 107.0
TLS3_k127_1385557_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1078.0
TLS3_k127_1385557_1 Sigma-54 interaction domain K10941 - - 0.0 1073.0
TLS3_k127_1385557_10 COG0515 Serine threonine protein - - - 0.000000000000000000000000000000000000000000000000005956 200.0
TLS3_k127_1385557_12 - - - - 0.000000000000000000000000000000000000004511 152.0
TLS3_k127_1385557_13 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000302 154.0
TLS3_k127_1385557_14 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.0000000000000000000000007659 118.0
TLS3_k127_1385557_15 dioxygenase activity K00477 - 1.14.11.18 0.000000000000000000008298 105.0
TLS3_k127_1385557_2 Signal transduction histidine kinase - - - 3.738e-288 901.0
TLS3_k127_1385557_3 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 556.0
TLS3_k127_1385557_4 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 469.0
TLS3_k127_1385557_5 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 376.0
TLS3_k127_1385557_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 328.0
TLS3_k127_1385557_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
TLS3_k127_1385557_9 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000006001 209.0
TLS3_k127_1396577_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 356.0
TLS3_k127_1396577_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000001462 188.0
TLS3_k127_1396577_2 YceI-like domain - - - 0.00000000000000000000000000000000000000001186 159.0
TLS3_k127_1396577_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000004182 140.0
TLS3_k127_1396577_4 Cytochrome c - - - 0.00000000000000000000000001111 123.0
TLS3_k127_1396577_5 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000002229 96.0
TLS3_k127_1398305_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.935e-317 976.0
TLS3_k127_1398305_1 synthase K01858 - 5.5.1.4 2.987e-225 704.0
TLS3_k127_1398305_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 310.0
TLS3_k127_1398305_11 Phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 312.0
TLS3_k127_1398305_12 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009222 249.0
TLS3_k127_1398305_14 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000002082 181.0
TLS3_k127_1398305_15 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000008 186.0
TLS3_k127_1398305_16 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000006058 165.0
TLS3_k127_1398305_17 phosphatidate phosphatase activity - - - 0.0000000000000000000000000000000000000000003485 180.0
TLS3_k127_1398305_18 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000002628 151.0
TLS3_k127_1398305_19 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000001064 137.0
TLS3_k127_1398305_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.071e-208 657.0
TLS3_k127_1398305_20 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000003783 149.0
TLS3_k127_1398305_21 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000007728 141.0
TLS3_k127_1398305_23 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000003194 72.0
TLS3_k127_1398305_24 Histidine kinase - - - 0.0002892 53.0
TLS3_k127_1398305_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 561.0
TLS3_k127_1398305_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 565.0
TLS3_k127_1398305_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 487.0
TLS3_k127_1398305_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 455.0
TLS3_k127_1398305_7 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 467.0
TLS3_k127_1398305_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 388.0
TLS3_k127_1398305_9 GtrA-like protein K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 352.0
TLS3_k127_1409233_0 Protein containing a von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 614.0
TLS3_k127_1409233_1 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 492.0
TLS3_k127_1409233_2 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 314.0
TLS3_k127_1409233_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001883 272.0
TLS3_k127_1409233_4 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000006204 191.0
TLS3_k127_1409233_5 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000004937 160.0
TLS3_k127_1409233_6 Flagellar filament outer layer protein Flaa - - - 0.0000000000000000000000000003901 130.0
TLS3_k127_1409233_7 FG-GAP repeat protein - - - 0.0000000000000000000004887 108.0
TLS3_k127_1409233_8 Zinc-binding dehydrogenase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005886,GO:0009507,GO:0009526,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009941,GO:0016020,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0071944 - 0.00001226 58.0
TLS3_k127_1417801_0 Prenylcysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 431.0
TLS3_k127_1417801_1 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 314.0
TLS3_k127_1417801_10 PFAM GCN5-related N-acetyltransferase - - - 0.00000003413 61.0
TLS3_k127_1417801_2 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003363 247.0
TLS3_k127_1417801_3 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001352 234.0
TLS3_k127_1417801_4 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000178 156.0
TLS3_k127_1417801_5 Protein of unknown function (DUF1501) - - - 0.0000000000000001518 92.0
TLS3_k127_1417801_6 Protein kinase domain - - - 0.00000000000003726 80.0
TLS3_k127_1417801_7 - - - - 0.00000000003458 67.0
TLS3_k127_1417801_8 DNA topological change - - - 0.000000002147 71.0
TLS3_k127_1430167_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 6.139e-249 774.0
TLS3_k127_1430167_1 Bacterial protein of unknown function (DUF885) - - - 1.777e-239 758.0
TLS3_k127_1430167_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 487.0
TLS3_k127_1430167_3 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 491.0
TLS3_k127_1430167_4 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 441.0
TLS3_k127_1430167_5 glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 337.0
TLS3_k127_1430167_6 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 334.0
TLS3_k127_1430167_7 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 337.0
TLS3_k127_1430167_9 Kazal type serine protease inhibitors - - - 0.0004613 51.0
TLS3_k127_1451726_0 Rieske [2Fe-2S] domain K00363 - 1.7.1.15 2.263e-217 689.0
TLS3_k127_1451726_1 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 429.0
TLS3_k127_1451726_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 432.0
TLS3_k127_1451726_3 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 369.0
TLS3_k127_1451726_4 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 338.0
TLS3_k127_1451726_5 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000000001007 202.0
TLS3_k127_1451726_6 YjbR - - - 0.0000000000000000000000000000000000000000000002126 169.0
TLS3_k127_1451726_7 self proteolysis - - - 0.00000000000000000000000001274 115.0
TLS3_k127_1451726_8 peptidyl-tyrosine sulfation - - - 0.00001551 48.0
TLS3_k127_1473266_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1399.0
TLS3_k127_1473266_1 thiolester hydrolase activity - - - 1.546e-211 675.0
TLS3_k127_1473266_10 nuclease activity K18828 - - 0.0000000000000000000000000000002472 126.0
TLS3_k127_1473266_11 - - - - 0.000000000000000000000000000001254 139.0
TLS3_k127_1473266_13 - - - - 0.0007624 51.0
TLS3_k127_1473266_2 Phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 564.0
TLS3_k127_1473266_3 Bile acid sodium symporter K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 361.0
TLS3_k127_1473266_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 360.0
TLS3_k127_1473266_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 338.0
TLS3_k127_1473266_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000001725 251.0
TLS3_k127_1473266_8 Globin - - - 0.00000000000000000000000000000000000000000000008447 174.0
TLS3_k127_1496379_0 transferase activity, transferring glycosyl groups K09809 - 2.7.8.12 2.204e-260 832.0
TLS3_k127_1496379_1 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 2.533e-228 736.0
TLS3_k127_1496379_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 617.0
TLS3_k127_1496379_3 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 488.0
TLS3_k127_1496379_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 449.0
TLS3_k127_1496379_5 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 439.0
TLS3_k127_1496379_6 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 292.0
TLS3_k127_1496379_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006391 261.0
TLS3_k127_1496379_8 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001299 248.0
TLS3_k127_1506217_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1993.0
TLS3_k127_1506217_1 AAA ATPase domain - - - 0.0 1290.0
TLS3_k127_1506217_10 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 348.0
TLS3_k127_1506217_11 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 300.0
TLS3_k127_1506217_12 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005223 267.0
TLS3_k127_1506217_13 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000305 263.0
TLS3_k127_1506217_15 Beta-lactamase class A K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000008565 207.0
TLS3_k127_1506217_16 Penicillinase repressor - - - 0.00000000000000000000000000000000000000000000000003634 181.0
TLS3_k127_1506217_18 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000007365 173.0
TLS3_k127_1506217_19 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000002224 145.0
TLS3_k127_1506217_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0 1173.0
TLS3_k127_1506217_20 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000001676 146.0
TLS3_k127_1506217_22 depolymerase - - - 0.0000000000000000000000000006627 125.0
TLS3_k127_1506217_23 FHA domain - - - 0.00000000000000000002824 106.0
TLS3_k127_1506217_24 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.000000000000002123 87.0
TLS3_k127_1506217_28 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000657 64.0
TLS3_k127_1506217_3 Elongation factor G, domain IV K02355 - - 0.0 1048.0
TLS3_k127_1506217_4 ErfK ybiS ycfS ynhG family protein - - - 1.393e-258 807.0
TLS3_k127_1506217_5 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 446.0
TLS3_k127_1506217_6 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 439.0
TLS3_k127_1506217_7 penicillin-binding protein K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 451.0
TLS3_k127_1506217_8 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 417.0
TLS3_k127_1506217_9 ABC-type transport system involved in multi-copper enzyme maturation permease component K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 413.0
TLS3_k127_1512821_0 ATPase family associated with various cellular activities (AAA) - - - 2.312e-248 784.0
TLS3_k127_1512821_1 phage tail tape measure protein - - - 0.0000000000000000000000000000000001519 137.0
TLS3_k127_1512821_2 - - - - 0.000000000000000000000000000000666 126.0
TLS3_k127_1512821_3 - - - - 0.0000000000000002348 94.0
TLS3_k127_1547427_0 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 464.0
TLS3_k127_1547427_1 Cytochrome P450 - - - 0.0000000000000000000000000000000000002399 141.0
TLS3_k127_1547427_2 - - - - 0.000000000000000005663 93.0
TLS3_k127_1547427_3 PFAM Alcohol dehydrogenase K13979 - - 0.00000001711 55.0
TLS3_k127_1547427_4 membrane K21741 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006089,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009438,GO:0009987,GO:0010035,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019172,GO:0019243,GO:0019249,GO:0019438,GO:0019752,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042180,GO:0042182,GO:0042221,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046185,GO:0046394,GO:0046483,GO:0050896,GO:0051596,GO:0061727,GO:0071704,GO:0071944,GO:0072330,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901530,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901700 - 0.00000005365 56.0
TLS3_k127_1554622_0 AAA ATPase domain - - - 2.528e-275 897.0
TLS3_k127_1554622_1 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003088 265.0
TLS3_k127_1557886_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1321.0
TLS3_k127_1557886_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 603.0
TLS3_k127_1557886_10 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000001691 221.0
TLS3_k127_1557886_11 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000002839 211.0
TLS3_k127_1557886_13 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000000000000017 158.0
TLS3_k127_1557886_15 - - - - 0.0000000000000006346 79.0
TLS3_k127_1557886_17 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000000003041 67.0
TLS3_k127_1557886_18 - - - - 0.00000003456 64.0
TLS3_k127_1557886_2 chlorophyll binding K02557,K03640,K12216 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 595.0
TLS3_k127_1557886_3 PFAM Acyl-CoA dehydrogenase, C-terminal domain K06445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 359.0
TLS3_k127_1557886_4 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 347.0
TLS3_k127_1557886_5 HAD-superfamily phosphatase, subfamily IIIC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 340.0
TLS3_k127_1557886_6 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 292.0
TLS3_k127_1557886_7 Pfam:Ureidogly_hydro K01483 - 4.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001538 263.0
TLS3_k127_1557886_8 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004389 248.0
TLS3_k127_1557886_9 anion transmembrane transporter activity K02028,K02045,K02049 - 3.6.3.21,3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000007471 248.0
TLS3_k127_1569840_0 AAA ATPase domain - - - 0.0 1221.0
TLS3_k127_1569840_1 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 445.0
TLS3_k127_1569840_2 PFAM cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008751 406.0
TLS3_k127_1569840_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 364.0
TLS3_k127_1569840_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 310.0
TLS3_k127_1569840_6 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000001548 155.0
TLS3_k127_1572190_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 620.0
TLS3_k127_1572190_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 583.0
TLS3_k127_1572190_2 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 549.0
TLS3_k127_1572190_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 392.0
TLS3_k127_1572190_4 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 311.0
TLS3_k127_1572190_5 Serine hydrolase (FSH1) K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 307.0
TLS3_k127_1572190_6 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000327 152.0
TLS3_k127_1572190_7 peptidyl-prolyl cis-trans isomerase activity K01802,K03769 - 5.2.1.8 0.0000000000000000000001736 104.0
TLS3_k127_1572190_9 Acetyltransferase (GNAT) family - - - 0.0000000639 57.0
TLS3_k127_158471_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 569.0
TLS3_k127_158471_1 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 391.0
TLS3_k127_158471_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 391.0
TLS3_k127_158471_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002379 273.0
TLS3_k127_1593696_0 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 387.0
TLS3_k127_1593696_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 338.0
TLS3_k127_1593696_3 PD-(D/E)XK nuclease superfamily - - - 0.00000000000004158 74.0
TLS3_k127_1596_0 Amidohydrolase family - - - 0.0 1038.0
TLS3_k127_1596_1 DNA helicase K03656,K03657 - 3.6.4.12 0.0 1026.0
TLS3_k127_1596_10 phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit K00479,K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 429.0
TLS3_k127_1596_11 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 425.0
TLS3_k127_1596_15 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 358.0
TLS3_k127_1596_16 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 362.0
TLS3_k127_1596_17 Transposase K07494 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 336.0
TLS3_k127_1596_18 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 317.0
TLS3_k127_1596_19 membrane K08989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 319.0
TLS3_k127_1596_2 Transmembrane secretion effector - - - 1.329e-231 729.0
TLS3_k127_1596_20 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 312.0
TLS3_k127_1596_21 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001115 287.0
TLS3_k127_1596_22 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002752 275.0
TLS3_k127_1596_23 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001435 259.0
TLS3_k127_1596_24 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000003301 253.0
TLS3_k127_1596_26 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007976 232.0
TLS3_k127_1596_27 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000007919 229.0
TLS3_k127_1596_29 HIT domain K02503 - - 0.0000000000000000000000000000000000000000008153 158.0
TLS3_k127_1596_3 Aminotransferase class I and II K00812 - 2.6.1.1 9.41e-208 655.0
TLS3_k127_1596_31 Belongs to the 'phage' integrase family - - - 0.000000000000000008389 95.0
TLS3_k127_1596_33 transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000004682 79.0
TLS3_k127_1596_34 DDE superfamily endonuclease - - - 0.0000000000000283 79.0
TLS3_k127_1596_35 PAP2 superfamily - - - 0.00000002837 57.0
TLS3_k127_1596_36 Methyltransferase domain - - - 0.0000002794 62.0
TLS3_k127_1596_37 - - - - 0.00006841 50.0
TLS3_k127_1596_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 580.0
TLS3_k127_1596_5 glutathionylspermidine amidase activity K01460 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464 3.5.1.78,6.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 555.0
TLS3_k127_1596_6 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 478.0
TLS3_k127_1596_7 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 441.0
TLS3_k127_1596_8 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 451.0
TLS3_k127_1596_9 Nucleotidyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 436.0
TLS3_k127_1598857_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 376.0
TLS3_k127_1598857_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 315.0
TLS3_k127_1598857_2 serine-type endopeptidase activity K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005331 250.0
TLS3_k127_1598857_4 - - - - 0.0000000000000000000000000000001292 128.0
TLS3_k127_1598857_5 Multicopper oxidase K00368,K22348,K22349 - 1.16.3.3,1.7.2.1 0.000003752 49.0
TLS3_k127_1656806_0 Putative glucoamylase K13688 - - 0.0 2431.0
TLS3_k127_1656806_1 ErfK ybiS ycfS ynhG family protein - - - 6.344e-261 820.0
TLS3_k127_1656806_2 Domain of unknown function (DUF4832) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 486.0
TLS3_k127_1656806_3 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 452.0
TLS3_k127_1656806_4 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 434.0
TLS3_k127_1656806_5 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 407.0
TLS3_k127_1656806_6 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003393 264.0
TLS3_k127_1656806_7 Member of a two-component regulatory system K02484,K07644,K07645,K18143 GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001567 260.0
TLS3_k127_1656806_9 Macro domain - - - 0.00000000000000000000000000000000000000000000000000003478 199.0
TLS3_k127_1684616_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1314.0
TLS3_k127_1684616_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0 1073.0
TLS3_k127_1684616_10 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 322.0
TLS3_k127_1684616_11 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 325.0
TLS3_k127_1684616_12 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 325.0
TLS3_k127_1684616_14 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008121 250.0
TLS3_k127_1684616_15 - - - - 0.00000000000000000000000000000000002595 140.0
TLS3_k127_1684616_16 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000004251 121.0
TLS3_k127_1684616_17 Sigma-70, region 4 K03088 - - 0.00000000000000000000003625 109.0
TLS3_k127_1684616_18 Pyrrolo-quinoline quinone - - - 0.0000000000000000005059 100.0
TLS3_k127_1684616_19 response to drug K03748 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0042221,GO:0042493,GO:0044425,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000003704 97.0
TLS3_k127_1684616_2 POT family K03305 - - 3.688e-258 804.0
TLS3_k127_1684616_20 helix_turn_helix, mercury resistance - - - 0.0000000000001463 83.0
TLS3_k127_1684616_21 -acetyltransferase - - - 0.00000000004758 72.0
TLS3_k127_1684616_22 marr family - - - 0.000002085 57.0
TLS3_k127_1684616_3 synthase K01858 - 5.5.1.4 3.953e-236 735.0
TLS3_k127_1684616_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.338e-229 720.0
TLS3_k127_1684616_5 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 551.0
TLS3_k127_1684616_6 His Kinase A (phosphoacceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 562.0
TLS3_k127_1684616_7 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 430.0
TLS3_k127_1684616_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 379.0
TLS3_k127_1684616_9 response regulator K03413,K04757,K17752 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 342.0
TLS3_k127_169774_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1905.0
TLS3_k127_169774_1 Domain of unknown function (DUF1998) K06877 - - 0.0 1205.0
TLS3_k127_169774_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0 1072.0
TLS3_k127_169774_3 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 480.0
TLS3_k127_169774_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000000005418 247.0
TLS3_k127_169774_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000003628 166.0
TLS3_k127_169774_6 - - - - 0.000000004008 63.0
TLS3_k127_1711718_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1045.0
TLS3_k127_1711718_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.366e-300 930.0
TLS3_k127_1711718_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000915 182.0
TLS3_k127_1711718_13 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0001057 49.0
TLS3_k127_1711718_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 571.0
TLS3_k127_1711718_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 424.0
TLS3_k127_1711718_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 337.0
TLS3_k127_1711718_5 STAS domain K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 329.0
TLS3_k127_1711718_6 Belongs to the SUA5 family K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 313.0
TLS3_k127_1711718_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006522 295.0
TLS3_k127_1711718_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000001841 221.0
TLS3_k127_1719994_0 AcrB/AcrD/AcrF family - - - 0.0 1388.0
TLS3_k127_1719994_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1127.0
TLS3_k127_1719994_10 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 353.0
TLS3_k127_1719994_11 metallocarboxypeptidase activity K01206,K01218 - 3.2.1.51,3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 337.0
TLS3_k127_1719994_12 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 304.0
TLS3_k127_1719994_13 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000001152 198.0
TLS3_k127_1719994_16 RNB K01147,K12573 - 3.1.13.1 0.000000000000000000000000000000000000000000000000004495 187.0
TLS3_k127_1719994_17 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000000000000000000000000009226 166.0
TLS3_k127_1719994_18 Protein required for attachment to host cells - - - 0.000000000000000000000000000000000001004 143.0
TLS3_k127_1719994_19 - - - - 0.00000000000000000000000000292 115.0
TLS3_k127_1719994_2 GAF domain - - - 5.871e-270 844.0
TLS3_k127_1719994_20 MafB19-like deaminase - - - 0.0000000000000000000003197 97.0
TLS3_k127_1719994_22 Transcription factor zinc-finger K09981 - - 0.0000000000000000001625 94.0
TLS3_k127_1719994_23 Immunity protein Imm1 - - - 0.00000000000000003073 88.0
TLS3_k127_1719994_24 4Fe-4S dicluster domain - - - 0.0000000000000006752 90.0
TLS3_k127_1719994_25 self proteolysis - - - 0.00000008049 58.0
TLS3_k127_1719994_26 peptidyl-tyrosine sulfation - - - 0.0000003881 62.0
TLS3_k127_1719994_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.536e-256 798.0
TLS3_k127_1719994_4 Histidine kinase - - - 9.46e-209 671.0
TLS3_k127_1719994_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 617.0
TLS3_k127_1719994_7 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 480.0
TLS3_k127_1719994_8 serine-type endopeptidase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 471.0
TLS3_k127_1719994_9 Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 392.0
TLS3_k127_1726262_0 peptidase activity, acting on L-amino acid peptides - - - 1.392e-261 827.0
TLS3_k127_1726262_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 617.0
TLS3_k127_1726262_10 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 281.0
TLS3_k127_1726262_11 DTW K05812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001229 286.0
TLS3_k127_1726262_12 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001634 273.0
TLS3_k127_1726262_13 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002542 249.0
TLS3_k127_1726262_14 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000005698 249.0
TLS3_k127_1726262_15 serine-type endopeptidase activity - - - 0.0000000000000000000000000000001239 137.0
TLS3_k127_1726262_16 MerR, DNA binding K19591 - - 0.00000000000000000000004982 106.0
TLS3_k127_1726262_18 - - - - 0.000004449 59.0
TLS3_k127_1726262_19 PFAM PEGA domain - - - 0.0007381 52.0
TLS3_k127_1726262_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 609.0
TLS3_k127_1726262_3 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 412.0
TLS3_k127_1726262_4 PFAM sigma-54 factor interaction domain-containing protein K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 379.0
TLS3_k127_1726262_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 332.0
TLS3_k127_1726262_6 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 335.0
TLS3_k127_1726262_7 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 314.0
TLS3_k127_1726262_8 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 301.0
TLS3_k127_1726262_9 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 296.0
TLS3_k127_1741713_0 PEGA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 368.0
TLS3_k127_1741713_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000363 247.0
TLS3_k127_1741713_2 - - - - 0.000000000000000297 89.0
TLS3_k127_1741713_3 serine threonine protein kinase - - - 0.000000001588 71.0
TLS3_k127_1750003_0 Peptidase family M50 K11749 - - 3.994e-302 932.0
TLS3_k127_1750003_1 nuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 546.0
TLS3_k127_1750003_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 541.0
TLS3_k127_1750003_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 558.0
TLS3_k127_1750003_4 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 406.0
TLS3_k127_1750003_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 365.0
TLS3_k127_1750003_6 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 331.0
TLS3_k127_1750003_7 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001815 276.0
TLS3_k127_1750003_8 Macro domain - - - 0.0000000000000000000000000000000000000000000000000000000000000101 221.0
TLS3_k127_1750003_9 - - - - 0.000000000000000000000000000000000000002478 162.0
TLS3_k127_1757635_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0 1600.0
TLS3_k127_1757635_1 Tetratricopeptide repeats - - - 1.333e-305 962.0
TLS3_k127_1757635_11 Tellurite resistance protein TerB K05801 - - 0.00000000000000000000000000000000000000000000000000001659 194.0
TLS3_k127_1757635_17 protein secretion K03116 - - 0.00000000000002886 77.0
TLS3_k127_1757635_2 Protein kinase domain - - - 3.272e-267 833.0
TLS3_k127_1757635_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 494.0
TLS3_k127_1757635_6 synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 344.0
TLS3_k127_1757635_7 Smr domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005535 254.0
TLS3_k127_1757635_8 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005329 243.0
TLS3_k127_1758134_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 3.311e-207 649.0
TLS3_k127_1758134_3 Belongs to the bacterial histone-like protein family K05788 - - 0.00000000000000000000000000000000000000000000000000000001077 198.0
TLS3_k127_1758134_4 polysaccharide deacetylase - - - 0.0000000000000000756 94.0
TLS3_k127_1765473_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1019.0
TLS3_k127_1765473_1 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 4.26e-318 996.0
TLS3_k127_1765473_10 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 377.0
TLS3_k127_1765473_11 Binding-protein-dependent transport system inner membrane component K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 378.0
TLS3_k127_1765473_12 Psort location Cytoplasmic, score K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 338.0
TLS3_k127_1765473_13 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 290.0
TLS3_k127_1765473_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002191 253.0
TLS3_k127_1765473_15 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002116 243.0
TLS3_k127_1765473_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000004216 201.0
TLS3_k127_1765473_18 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000001989 194.0
TLS3_k127_1765473_2 ABC-type uncharacterized transport system - - - 1.122e-268 839.0
TLS3_k127_1765473_22 SnoaL-like domain - - - 0.00000000000000000000000000000009697 130.0
TLS3_k127_1765473_24 Heavy-metal-associated domain K07213 - - 0.00000000000007745 74.0
TLS3_k127_1765473_26 - - - - 0.00000000004092 76.0
TLS3_k127_1765473_27 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000001101 58.0
TLS3_k127_1765473_28 Worm-specific repeat type 1 - - - 0.00004077 56.0
TLS3_k127_1765473_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 580.0
TLS3_k127_1765473_5 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 577.0
TLS3_k127_1765473_6 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 486.0
TLS3_k127_1765473_7 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 450.0
TLS3_k127_1765473_8 sulfate ABC transporter K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 404.0
TLS3_k127_1765473_9 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 392.0
TLS3_k127_1767939_0 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.0 1087.0
TLS3_k127_1767939_1 - - - - 4.914e-273 857.0
TLS3_k127_1767939_10 Phosphocarrier protein HPR K11189 - - 0.00000000000000000000000000000000006938 136.0
TLS3_k127_1767939_12 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.000000000000000000000001627 109.0
TLS3_k127_1767939_13 Protein conserved in bacteria K09774 - - 0.0000000000002 76.0
TLS3_k127_1767939_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 1.62e-255 807.0
TLS3_k127_1767939_3 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 578.0
TLS3_k127_1767939_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 487.0
TLS3_k127_1767939_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 470.0
TLS3_k127_1767939_6 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001158 280.0
TLS3_k127_1767939_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000002286 221.0
TLS3_k127_1767939_8 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.000000000000000000000000000000000000000001384 160.0
TLS3_k127_1767939_9 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000008729 171.0
TLS3_k127_1777142_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 6.936e-231 731.0
TLS3_k127_1777142_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 402.0
TLS3_k127_1777142_2 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 395.0
TLS3_k127_1777142_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003536 230.0
TLS3_k127_1777142_5 - - - - 0.00000000001657 78.0
TLS3_k127_1781051_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 5.195e-247 771.0
TLS3_k127_1781051_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 614.0
TLS3_k127_1781051_10 Family membership K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 331.0
TLS3_k127_1781051_11 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 334.0
TLS3_k127_1781051_12 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000008278 263.0
TLS3_k127_1781051_13 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000000002288 214.0
TLS3_k127_1781051_14 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000001991 222.0
TLS3_k127_1781051_15 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000007127 210.0
TLS3_k127_1781051_16 protein secretion K03116,K03117 GO:0003674,GO:0005215 - 0.000000000000000000000000000000000000009179 154.0
TLS3_k127_1781051_2 long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 606.0
TLS3_k127_1781051_3 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 511.0
TLS3_k127_1781051_4 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 502.0
TLS3_k127_1781051_5 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 464.0
TLS3_k127_1781051_6 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 413.0
TLS3_k127_1781051_7 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 408.0
TLS3_k127_1781051_8 KAP family P-loop domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 387.0
TLS3_k127_1781051_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 390.0
TLS3_k127_178146_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1654.0
TLS3_k127_178146_1 TonB-dependent Receptor Plug Domain - - - 4.297e-258 810.0
TLS3_k127_178146_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 8.166e-201 634.0
TLS3_k127_178146_3 type III restriction protein res subunit K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 471.0
TLS3_k127_178146_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 402.0
TLS3_k127_178146_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000005023 145.0
TLS3_k127_178146_7 - - - - 0.0000000000000000000000000001842 121.0
TLS3_k127_178146_9 - - - - 0.00000000000000001088 88.0
TLS3_k127_1795859_0 4Fe-4S dicluster domain K00184 - - 0.0 1122.0
TLS3_k127_1795859_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 2.833e-269 857.0
TLS3_k127_1795859_10 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001118 252.0
TLS3_k127_1795859_11 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000321 257.0
TLS3_k127_1795859_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000001618 179.0
TLS3_k127_1795859_14 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05568 - - 0.00000000000000000007335 93.0
TLS3_k127_1795859_16 - - - - 0.000001619 61.0
TLS3_k127_1795859_17 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0005067 45.0
TLS3_k127_1795859_2 Polysulphide reductase, NrfD K00185 - - 1.268e-225 706.0
TLS3_k127_1795859_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 482.0
TLS3_k127_1795859_4 Cell division protein FtsI penicillin-binding protein 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 430.0
TLS3_k127_1795859_5 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 419.0
TLS3_k127_1795859_6 ethanolamine kinase activity K07251 - 2.7.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 393.0
TLS3_k127_1795859_7 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 339.0
TLS3_k127_1795859_8 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 298.0
TLS3_k127_1795859_9 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 302.0
TLS3_k127_1810568_0 DEAD/H associated K03724 - - 0.0 1713.0
TLS3_k127_1810568_1 IgGFc binding protein - - - 5.157e-270 842.0
TLS3_k127_1810568_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 418.0
TLS3_k127_1810568_3 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000002141 242.0
TLS3_k127_1810568_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000009944 162.0
TLS3_k127_1810804_0 fatty-acyl-CoA reductase (alcohol-forming) activity K01897,K12421 - 6.2.1.3 0.0 1268.0
TLS3_k127_1810804_1 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 7.058e-255 803.0
TLS3_k127_1810804_10 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 420.0
TLS3_k127_1810804_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 396.0
TLS3_k127_1810804_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 366.0
TLS3_k127_1810804_13 PFAM Fibronectin type III domain protein K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 387.0
TLS3_k127_1810804_14 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 355.0
TLS3_k127_1810804_15 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 333.0
TLS3_k127_1810804_16 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 315.0
TLS3_k127_1810804_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002499 291.0
TLS3_k127_1810804_19 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000000002127 220.0
TLS3_k127_1810804_2 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 1.283e-239 764.0
TLS3_k127_1810804_20 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000002255 212.0
TLS3_k127_1810804_21 Chemotaxis protein CheY K03413 - - 0.000000000000000000000000000001588 128.0
TLS3_k127_1810804_22 - - - - 0.0000000003317 69.0
TLS3_k127_1810804_23 Transcriptional regulator - - - 0.00002481 58.0
TLS3_k127_1810804_24 Chemotaxis protein CheY K03413 - - 0.0002294 44.0
TLS3_k127_1810804_3 Sugar (and other) transporter - - - 1.328e-229 721.0
TLS3_k127_1810804_4 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 563.0
TLS3_k127_1810804_5 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 529.0
TLS3_k127_1810804_6 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 542.0
TLS3_k127_1810804_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 497.0
TLS3_k127_1810804_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 481.0
TLS3_k127_1810804_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 426.0
TLS3_k127_1814325_0 Tetratricopeptide repeat - - - 0.0 1848.0
TLS3_k127_1814325_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 622.0
TLS3_k127_1814325_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000002364 247.0
TLS3_k127_1814325_11 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000002757 218.0
TLS3_k127_1814325_14 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000001113 166.0
TLS3_k127_1814325_18 lipopolysaccharide transmembrane transporter activity K07058 - - 0.0000000000002136 82.0
TLS3_k127_1814325_2 Prolyl oligopeptidase, N-terminal beta-propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 555.0
TLS3_k127_1814325_20 phospho-2-dehydro-3-deoxyheptonate aldolase - - - 0.00000000002616 72.0
TLS3_k127_1814325_23 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000004791 62.0
TLS3_k127_1814325_24 Carboxylesterase family - - - 0.000001776 60.0
TLS3_k127_1814325_25 phospho-2-dehydro-3-deoxyheptonate aldolase - - - 0.0003933 50.0
TLS3_k127_1814325_3 Surface antigen K07277,K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 495.0
TLS3_k127_1814325_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 439.0
TLS3_k127_1814325_5 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 327.0
TLS3_k127_1814325_7 ACT domain K03567 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002194 267.0
TLS3_k127_1814325_8 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000104 259.0
TLS3_k127_1832169_0 Radical SAM - - - 6.242e-244 779.0
TLS3_k127_1832169_1 Uncharacterized protein conserved in bacteria (DUF2169) - - - 1.902e-239 764.0
TLS3_k127_1832169_10 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 408.0
TLS3_k127_1832169_11 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 344.0
TLS3_k127_1832169_12 Belongs to the peptidase S1B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 342.0
TLS3_k127_1832169_13 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 335.0
TLS3_k127_1832169_14 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 308.0
TLS3_k127_1832169_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 304.0
TLS3_k127_1832169_19 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000007065 205.0
TLS3_k127_1832169_2 protein conserved in bacteria K11904 - - 5.707e-228 732.0
TLS3_k127_1832169_24 Pentapeptide repeats (8 copies) - - - 0.00000000000000000000003456 107.0
TLS3_k127_1832169_3 protein conserved in bacteria K11904 - - 4.879e-222 710.0
TLS3_k127_1832169_4 protein conserved in bacteria K11904 - - 1.4e-215 691.0
TLS3_k127_1832169_5 protein conserved in bacteria K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 609.0
TLS3_k127_1832169_6 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 604.0
TLS3_k127_1832169_7 FHA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 593.0
TLS3_k127_1832169_8 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 565.0
TLS3_k127_1832169_9 low-complexity proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 540.0
TLS3_k127_1871691_0 cell adhesion involved in biofilm formation - - - 1.697e-212 687.0
TLS3_k127_1871691_1 Acts as a magnesium transporter K06213 - - 5.815e-211 663.0
TLS3_k127_1871691_2 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 568.0
TLS3_k127_1871691_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 420.0
TLS3_k127_1871691_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000006149 206.0
TLS3_k127_1871691_5 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000001103 196.0
TLS3_k127_1871691_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000001599 186.0
TLS3_k127_1877984_0 Phytoene dehydrogenase and related proteins - - - 8.178e-195 620.0
TLS3_k127_1877984_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 406.0
TLS3_k127_1877984_2 Belongs to the HAD-like hydrolase superfamily. PhnX family K05306 - 3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003553 269.0
TLS3_k127_1877984_3 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005171 247.0
TLS3_k127_1877984_4 NADPH quinone reductase K00344 - 1.6.5.5 0.0000000000000103 79.0
TLS3_k127_1877984_6 Belongs to the Dps family K04047 - - 0.000000000002236 72.0
TLS3_k127_1877984_8 TIR domain - - - 0.00001512 48.0
TLS3_k127_1877984_9 - - - - 0.0001409 52.0
TLS3_k127_1881935_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 600.0
TLS3_k127_1881935_3 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000004308 177.0
TLS3_k127_1881935_4 Histidine kinase - - - 0.0000000007753 71.0
TLS3_k127_1882492_0 SMART serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 368.0
TLS3_k127_1882492_1 - - - - 0.000000000000000000000000000000000000000000000000000000000002055 217.0
TLS3_k127_1882492_2 Cadherin domain - - - 0.000000002783 72.0
TLS3_k127_1896_0 non-ribosomal peptide synthetase - - - 6.274e-273 908.0
TLS3_k127_1896_1 polyketide synthase K04786 - - 2.025e-226 753.0
TLS3_k127_1896_10 Proposed nucleic acid binding domain - - - 0.0000000002297 74.0
TLS3_k127_1896_14 - - - - 0.00003567 56.0
TLS3_k127_1896_15 SNAP receptor activity - - - 0.00004198 55.0
TLS3_k127_1896_2 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 495.0
TLS3_k127_1896_3 isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 321.0
TLS3_k127_1896_4 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000753 220.0
TLS3_k127_1896_6 antisigma factor binding - - - 0.0000000000000000000000003512 114.0
TLS3_k127_1896_7 GntR family transcriptional regulator - - - 0.000000000000002177 79.0
TLS3_k127_1896_8 Thioesterase domain - - - 0.00000000000001696 87.0
TLS3_k127_1896_9 - - - - 0.00000000000343 78.0
TLS3_k127_1908152_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0 1751.0
TLS3_k127_1908152_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 490.0
TLS3_k127_1908152_2 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 396.0
TLS3_k127_1908152_3 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 311.0
TLS3_k127_1908152_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000006558 224.0
TLS3_k127_1908152_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000007031 202.0
TLS3_k127_1908152_6 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013,K16014 - - 0.00000000000000000000000000000000000000000008665 179.0
TLS3_k127_1908152_7 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000396 109.0
TLS3_k127_1908152_8 Restriction endonuclease K07448 - - 0.000000003597 65.0
TLS3_k127_1950085_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.71e-214 683.0
TLS3_k127_1950085_1 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 524.0
TLS3_k127_1950085_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 413.0
TLS3_k127_1950085_4 Mo-molybdopterin cofactor metabolic process K03636,K21142 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.12 0.000000000000000000000000000001004 122.0
TLS3_k127_1950085_5 carboxymuconolactone decarboxylase - - - 0.000000000000005991 83.0
TLS3_k127_1950085_7 High confidence in function and specificity - - - 0.00000000001573 72.0
TLS3_k127_1955406_0 Cytochrome c K00428 - 1.11.1.5 1.4e-296 917.0
TLS3_k127_1955406_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.217e-273 846.0
TLS3_k127_1955406_2 Aldehyde dehydrogenase family K00137 - 1.2.1.19 4.465e-229 725.0
TLS3_k127_1955406_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 449.0
TLS3_k127_1955406_4 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000001114 235.0
TLS3_k127_1955406_5 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000003207 150.0
TLS3_k127_1955406_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000001423 148.0
TLS3_k127_1955406_9 Predicted membrane protein (DUF2085) - - - 0.000000000000000000007557 103.0
TLS3_k127_1956252_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 612.0
TLS3_k127_1956252_2 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 385.0
TLS3_k127_1974004_0 Family membership - - - 0.0 1716.0
TLS3_k127_1974004_1 Cysteine-rich domain K00113 - 1.1.5.3 1.237e-211 666.0
TLS3_k127_1974004_10 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001163 268.0
TLS3_k127_1974004_11 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001752 263.0
TLS3_k127_1974004_12 Belongs to the Fur family K09825,K22297 - - 0.000000000000000000000000000000000000000000000000000000000000000001103 231.0
TLS3_k127_1974004_13 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000005555 255.0
TLS3_k127_1974004_14 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000389 240.0
TLS3_k127_1974004_15 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000007375 215.0
TLS3_k127_1974004_16 - - - - 0.000000000000000000000000000000000000000000000000000000000003832 227.0
TLS3_k127_1974004_17 - - - - 0.0000000000000000000000000000000000000000000017 172.0
TLS3_k127_1974004_18 Thioesterase-like superfamily K01075 - 3.1.2.23 0.0000000000000000000000000000000000000000001139 175.0
TLS3_k127_1974004_19 Domain of unknown function (DUF3817) - - - 0.000000000000000000000000000000000001047 149.0
TLS3_k127_1974004_2 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 603.0
TLS3_k127_1974004_20 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.0000000000000000000000000000005631 138.0
TLS3_k127_1974004_22 sequence-specific DNA binding K13633 - - 0.0000000000000000000000000006644 119.0
TLS3_k127_1974004_23 cheY-homologous receiver domain - - - 0.0000000000000000000000465 106.0
TLS3_k127_1974004_24 cheY-homologous receiver domain - - - 0.00000000000001389 80.0
TLS3_k127_1974004_25 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000001784 63.0
TLS3_k127_1974004_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 415.0
TLS3_k127_1974004_4 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 411.0
TLS3_k127_1974004_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 392.0
TLS3_k127_1974004_7 chitinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 317.0
TLS3_k127_1974004_8 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 323.0
TLS3_k127_1974004_9 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007468 285.0
TLS3_k127_1977492_0 Family membership - - - 0.0 1317.0
TLS3_k127_1977492_1 ABC-type transport system involved in lipoprotein release permease component K09808 - - 4.784e-243 763.0
TLS3_k127_1977492_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 544.0
TLS3_k127_1977492_3 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 488.0
TLS3_k127_1977492_4 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 484.0
TLS3_k127_1977492_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 364.0
TLS3_k127_1977492_6 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 332.0
TLS3_k127_1977492_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 299.0
TLS3_k127_1977492_8 guanyl-nucleotide exchange factor activity K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002881 290.0
TLS3_k127_2012200_0 Bacterial regulatory protein, Fis family K07712 - - 1.976e-225 709.0
TLS3_k127_2012200_1 Dual-action HEIGH metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 486.0
TLS3_k127_2012200_2 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 359.0
TLS3_k127_2012200_4 NAD dependent epimerase dehydratase family protein K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001019 285.0
TLS3_k127_2012200_5 cog0421, spermidine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000002607 234.0
TLS3_k127_2012200_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000171 198.0
TLS3_k127_2012200_7 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000215 126.0
TLS3_k127_2012200_8 cheY-homologous receiver domain K07814 - - 0.0000000000000000004144 92.0
TLS3_k127_2032365_0 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 351.0
TLS3_k127_2032365_1 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000211 248.0
TLS3_k127_2032365_2 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000001117 218.0
TLS3_k127_2032365_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000004862 201.0
TLS3_k127_2035914_0 - - - - 2.713e-241 766.0
TLS3_k127_2035914_1 PFAM Archaeal ATPase - - - 5.62e-196 626.0
TLS3_k127_2035914_10 Bacterial Ig-like domain (group 1) - - - 0.000000000000000000000000000000000000002105 168.0
TLS3_k127_2035914_11 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.000000000000000000000000000000000000004332 153.0
TLS3_k127_2035914_13 RHS repeat-associated core domain - - - 0.00000000000000000000000000001474 125.0
TLS3_k127_2035914_15 Ntpase (Nacht family) - - - 0.000000000000000000000008547 110.0
TLS3_k127_2035914_16 Protein of unknown function (DUF416) K09891 - - 0.00000000001927 72.0
TLS3_k127_2035914_18 - - - - 0.0000001856 60.0
TLS3_k127_2035914_2 COG0618 Exopolyphosphatase-related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 507.0
TLS3_k127_2035914_3 PFAM Acetyl-CoA hydrolase transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 465.0
TLS3_k127_2035914_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 422.0
TLS3_k127_2035914_5 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 335.0
TLS3_k127_2035914_6 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007048 270.0
TLS3_k127_2035914_7 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000001249 219.0
TLS3_k127_2035914_8 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000002423 202.0
TLS3_k127_2035914_9 RHS Repeat - - - 0.00000000000000000000000000000000000000000005222 174.0
TLS3_k127_2043477_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1992.0
TLS3_k127_2043477_1 IgGFc binding protein - - - 1.637e-282 914.0
TLS3_k127_2043477_11 Protein conserved in bacteria - - - 0.000000000000000000000009207 107.0
TLS3_k127_2043477_13 ig-like, plexins, transcription factors - - - 0.0000000000003138 83.0
TLS3_k127_2043477_14 E3 Ubiquitin ligase - - - 0.000002507 61.0
TLS3_k127_2043477_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 7.261e-245 774.0
TLS3_k127_2043477_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 608.0
TLS3_k127_2043477_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 531.0
TLS3_k127_2043477_6 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 471.0
TLS3_k127_2043477_7 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648,K11381,K18002 - 1.2.4.4,2.3.1.180,2.3.1.230 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009781 298.0
TLS3_k127_2043477_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000007697 221.0
TLS3_k127_2043477_9 FIST N domain - - - 0.00000000000000000000000000000000000000000000000000000000000005048 220.0
TLS3_k127_2048657_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1358.0
TLS3_k127_2048657_1 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 1.132e-260 817.0
TLS3_k127_2048657_10 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 494.0
TLS3_k127_2048657_11 Fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 463.0
TLS3_k127_2048657_12 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 424.0
TLS3_k127_2048657_13 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 431.0
TLS3_k127_2048657_14 nitrite reductase (NAD(P)H) large subunit K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 437.0
TLS3_k127_2048657_15 Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 398.0
TLS3_k127_2048657_16 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 369.0
TLS3_k127_2048657_17 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 350.0
TLS3_k127_2048657_18 protein kinase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 340.0
TLS3_k127_2048657_2 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 1.29e-242 758.0
TLS3_k127_2048657_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002676 261.0
TLS3_k127_2048657_21 transmembrane signaling receptor activity - - - 0.000000000000000000000000000000000000000000000000000000000000001887 226.0
TLS3_k127_2048657_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000002786 211.0
TLS3_k127_2048657_23 4-vinyl reductase, 4VR K07013 - - 0.0000000000000000000000000000000000000000000000000001171 190.0
TLS3_k127_2048657_24 PAAR motif protein - - - 0.0000000000000000000000000000000000000000000000000006138 191.0
TLS3_k127_2048657_25 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000001469 180.0
TLS3_k127_2048657_26 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000009868 182.0
TLS3_k127_2048657_27 His Kinase A (phosphoacceptor) domain K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000002348 170.0
TLS3_k127_2048657_28 domain, Protein - - - 0.0000000000000000000000000000000000000004462 168.0
TLS3_k127_2048657_29 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000006036 130.0
TLS3_k127_2048657_30 - - - - 0.000000000000000000000000000008928 131.0
TLS3_k127_2048657_31 PFAM Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000001012 119.0
TLS3_k127_2048657_32 cytochrome - - - 0.0000000000000000000000000001374 123.0
TLS3_k127_2048657_33 domain, Protein K00573,K02335 - 2.1.1.77,2.7.7.7 0.00000000000000000000009674 113.0
TLS3_k127_2048657_35 Cytochrome c - - - 0.00000000000004728 78.0
TLS3_k127_2048657_36 - - - - 0.0000000000001139 84.0
TLS3_k127_2048657_37 Belongs to the ompA family K03640 - - 0.0000000000005342 78.0
TLS3_k127_2048657_38 - - - - 0.00000006147 61.0
TLS3_k127_2048657_4 phosphorelay signal transduction system K10941,K21405 - - 4.503e-235 737.0
TLS3_k127_2048657_5 Protein of unknown function (DUF1592) - - - 3.785e-210 666.0
TLS3_k127_2048657_6 chitinase K01183 - 3.2.1.14 8.14e-207 653.0
TLS3_k127_2048657_7 Protein of unknown function (DUF1552) - - - 1.462e-196 622.0
TLS3_k127_2048657_8 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 566.0
TLS3_k127_2048657_9 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 555.0
TLS3_k127_2053177_0 Protein kinase domain - - - 3.619e-232 751.0
TLS3_k127_2053177_1 O-Antigen ligase - - - 5.756e-221 717.0
TLS3_k127_2053177_10 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000009809 138.0
TLS3_k127_2053177_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 511.0
TLS3_k127_2053177_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 465.0
TLS3_k127_2053177_4 Bacterial transferase hexapeptide (six repeats) K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 308.0
TLS3_k127_2053177_6 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000005743 208.0
TLS3_k127_2053177_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000001253 211.0
TLS3_k127_2053177_8 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000009459 198.0
TLS3_k127_2053177_9 - - - - 0.000000000000000000000000000000000000000005346 164.0
TLS3_k127_2063739_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 582.0
TLS3_k127_2063739_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 436.0
TLS3_k127_2063739_3 STAS domain K17763 - - 0.000000003321 59.0
TLS3_k127_2087446_0 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 497.0
TLS3_k127_2087446_11 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000001378 80.0
TLS3_k127_2087446_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 404.0
TLS3_k127_2087446_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 353.0
TLS3_k127_2087446_4 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 318.0
TLS3_k127_2087446_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008148 255.0
TLS3_k127_2087446_6 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001589 237.0
TLS3_k127_2087446_7 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000003359 199.0
TLS3_k127_2089903_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 2.496e-209 672.0
TLS3_k127_2089903_1 ERAP1-like C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 590.0
TLS3_k127_2089903_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 293.0
TLS3_k127_2089903_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
TLS3_k127_2089903_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002907 284.0
TLS3_k127_2089903_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002554 275.0
TLS3_k127_2089903_6 alkyl hydroperoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003119 237.0
TLS3_k127_2089903_7 phosphohydrolase K21196 - 1.13.11.78 0.0000000000000000000000000000000000000000000000001682 184.0
TLS3_k127_2089903_8 cell redox homeostasis - - - 0.000000000000000000000000000000000000000003428 162.0
TLS3_k127_209548_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 336.0
TLS3_k127_2117928_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 587.0
TLS3_k127_2117928_1 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 465.0
TLS3_k127_2117928_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 349.0
TLS3_k127_2117928_3 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000009828 222.0
TLS3_k127_2117928_4 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000109 189.0
TLS3_k127_2117928_5 PFAM Sulfate transporter antisigma-factor antagonist STAS K17763 - - 0.0000000000000000000000000000000000000000000002744 180.0
TLS3_k127_2129950_0 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0 1841.0
TLS3_k127_2134177_0 von Willebrand factor type A domain - - - 0.0 1391.0
TLS3_k127_2134177_1 Aerotolerance regulator N-terminal - - - 5.673e-285 891.0
TLS3_k127_2134177_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 308.0
TLS3_k127_2134177_11 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002721 295.0
TLS3_k127_2134177_13 Spherulation-specific family 4 - - - 0.00000000000000000000000000000000000000000000000001658 194.0
TLS3_k127_2134177_15 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000002467 186.0
TLS3_k127_2134177_17 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.0000000000000000000000000000000002769 141.0
TLS3_k127_2134177_19 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000001297 52.0
TLS3_k127_2134177_2 Major facilitator superfamily - - - 2.676e-200 634.0
TLS3_k127_2134177_20 Zinc metalloprotease (Elastase) K01399,K08604 - 3.4.24.25,3.4.24.26 0.000525 51.0
TLS3_k127_2134177_3 HAMP domain K07641,K14980 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 606.0
TLS3_k127_2134177_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 448.0
TLS3_k127_2134177_5 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 443.0
TLS3_k127_2134177_6 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 420.0
TLS3_k127_2134177_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 428.0
TLS3_k127_2134177_8 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 376.0
TLS3_k127_2134177_9 Transcriptional regulatory protein, C terminal K02483,K07663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 345.0
TLS3_k127_2136067_0 6-phosphogluconolactonase activity - - - 0.0 1279.0
TLS3_k127_2136067_1 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 5e-323 994.0
TLS3_k127_2136067_10 - - - - 0.0000000000000000000000000000693 120.0
TLS3_k127_2136067_11 Anti-anti sigma factor protein K17763 - - 0.0000489 46.0
TLS3_k127_2136067_2 Major facilitator superfamily K02429 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 475.0
TLS3_k127_2136067_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 424.0
TLS3_k127_2136067_4 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 403.0
TLS3_k127_2136067_5 transcription factor binding K07315,K17763 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 358.0
TLS3_k127_2136067_6 Urease, gamma subunit K01430,K14048 - 3.5.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 335.0
TLS3_k127_2136067_7 TonB dependent receptor K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 288.0
TLS3_k127_2136067_8 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002495 282.0
TLS3_k127_2136067_9 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003831 254.0
TLS3_k127_2147638_0 COG0618 Exopolyphosphatase-related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 474.0
TLS3_k127_2147638_10 Fatty acid desaturase - - - 0.000002543 53.0
TLS3_k127_2147638_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 411.0
TLS3_k127_2147638_4 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 329.0
TLS3_k127_2147638_5 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000006485 270.0
TLS3_k127_2147638_6 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001574 251.0
TLS3_k127_2147638_7 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001977 201.0
TLS3_k127_2147638_8 NUDIX domain - - - 0.000000000000000000000000000000000003928 150.0
TLS3_k127_2147638_9 oligosaccharyl transferase activity - - - 0.0000000000000000000000000036 128.0
TLS3_k127_2170584_0 ErfK ybiS ycfS ynhG family protein - - - 6.033e-196 630.0
TLS3_k127_2170584_1 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 479.0
TLS3_k127_2170584_11 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000006119 60.0
TLS3_k127_2170584_12 - - - - 0.000003728 60.0
TLS3_k127_2170584_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 462.0
TLS3_k127_2170584_3 Penicillin-insensitive murein endopeptidase K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 392.0
TLS3_k127_2170584_4 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 327.0
TLS3_k127_2170584_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001952 288.0
TLS3_k127_2170584_6 bacterial-type flagellum organization K02411 - - 0.000000000000000000000000000000000000000000000000000000000000000000006068 244.0
TLS3_k127_2170584_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001577 246.0
TLS3_k127_2170584_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000001998 134.0
TLS3_k127_2170584_9 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000002683 128.0
TLS3_k127_2179679_0 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 541.0
TLS3_k127_2179679_1 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 530.0
TLS3_k127_2179679_2 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 376.0
TLS3_k127_2219512_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 3.375e-219 687.0
TLS3_k127_2219512_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 439.0
TLS3_k127_2219512_2 Polysaccharide biosynthesis protein K03328 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 413.0
TLS3_k127_2219512_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 314.0
TLS3_k127_2219512_4 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001199 280.0
TLS3_k127_2219512_5 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000001915 205.0
TLS3_k127_2219512_6 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000002783 95.0
TLS3_k127_2219512_7 Psort location Cytoplasmic, score 8.87 - - - 0.000000007412 60.0
TLS3_k127_2265582_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1039.0
TLS3_k127_2265582_1 Belongs to the aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 4.479e-269 837.0
TLS3_k127_2265582_2 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 578.0
TLS3_k127_2265582_3 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 486.0
TLS3_k127_2265582_5 Glycoside hydrolase family 16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005218 282.0
TLS3_k127_2265582_9 Putative transposase, YhgA-like - - - 0.000000000001088 70.0
TLS3_k127_2275297_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.791e-309 969.0
TLS3_k127_2275297_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000002126 125.0
TLS3_k127_2279657_0 Family membership - - - 0.0 1090.0
TLS3_k127_2279657_1 Protein conserved in bacteria - - - 9.869e-265 836.0
TLS3_k127_2279657_11 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000000000000009412 214.0
TLS3_k127_2279657_12 4Fe-4S binding domain - - - 0.0000000000000000000000000446 114.0
TLS3_k127_2279657_2 Protein conserved in bacteria - - - 1.362e-229 730.0
TLS3_k127_2279657_3 Aminotransferase K00813,K00832 GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0008793,GO:0009058,GO:0009066,GO:0009067,GO:0009072,GO:0009073,GO:0009081,GO:0009082,GO:0009094,GO:0009095,GO:0009098,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019292,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050048,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.6.1.1,2.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 561.0
TLS3_k127_2279657_4 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 532.0
TLS3_k127_2279657_5 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 502.0
TLS3_k127_2279657_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 353.0
TLS3_k127_2279657_7 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 333.0
TLS3_k127_2279657_8 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001762 263.0
TLS3_k127_2279657_9 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003731 273.0
TLS3_k127_2280898_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0 1105.0
TLS3_k127_2280898_1 non-ribosomal peptide synthetase - - - 0.0 1035.0
TLS3_k127_2280898_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 389.0
TLS3_k127_2280898_3 Amino acid adenylation enzyme thioester reductase family protein - - - 0.000000000000000000000000000000000000000000000000000000000001571 228.0
TLS3_k127_2297350_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 440.0
TLS3_k127_2297350_1 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000001537 180.0
TLS3_k127_2297350_2 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000004076 139.0
TLS3_k127_2297350_3 Type VI secretion system effector, Hcp K11903 - - 0.000000003182 58.0
TLS3_k127_2345495_0 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 3.788e-292 903.0
TLS3_k127_2345495_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.511e-262 826.0
TLS3_k127_2345495_10 Protein serine threonine phosphatase K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 412.0
TLS3_k127_2345495_11 belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 422.0
TLS3_k127_2345495_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 384.0
TLS3_k127_2345495_13 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000004077 219.0
TLS3_k127_2345495_14 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K15520 - 2.3.1.189 0.00000000000000000000000000000000000000000000000000001155 198.0
TLS3_k127_2345495_15 Phage lysozyme K01185 - 3.2.1.17 0.0000636 55.0
TLS3_k127_2345495_2 PhoQ Sensor - - - 4.173e-243 774.0
TLS3_k127_2345495_3 Sigma-54 interaction domain - - - 1.993e-230 737.0
TLS3_k127_2345495_4 UDP binding domain K00012 - 1.1.1.22 9.454e-216 680.0
TLS3_k127_2345495_5 DbpA RNA binding domain K05592 - 3.6.4.13 4.094e-203 652.0
TLS3_k127_2345495_6 Molecular chaperone. Has ATPase activity K04079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 557.0
TLS3_k127_2345495_8 Sterol desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 506.0
TLS3_k127_2354424_1 Circularly permuted ATP-grasp type 2 - - - 8.271e-245 772.0
TLS3_k127_2354424_11 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001482 244.0
TLS3_k127_2354424_12 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000002402 236.0
TLS3_k127_2354424_13 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000000000000000000000000009463 233.0
TLS3_k127_2354424_14 - - - - 0.0000000000000000000000000000000000000000000151 182.0
TLS3_k127_2354424_16 light absorption - - - 0.000000000000000000000000000000000006706 144.0
TLS3_k127_2354424_17 COGs COG1033 exporter of the RND superfamily protein K07003 - - 0.00000000000000000000000000000000001231 158.0
TLS3_k127_2354424_19 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000002127 139.0
TLS3_k127_2354424_2 Bacterial transglutaminase-like N-terminal region - - - 2.099e-235 741.0
TLS3_k127_2354424_21 Exporters of the RND superfamily K07003 - - 0.000000001855 72.0
TLS3_k127_2354424_3 Type II restriction enzyme, methylase subunits - - - 9.786e-221 713.0
TLS3_k127_2354424_4 5' nucleotidase family - - - 8.37e-213 672.0
TLS3_k127_2354424_5 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 454.0
TLS3_k127_2354424_6 Pfam Amidohydrolase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 398.0
TLS3_k127_2354424_7 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 411.0
TLS3_k127_2354424_8 of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003967 280.0
TLS3_k127_2354424_9 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001141 271.0
TLS3_k127_2358089_0 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000001867 167.0
TLS3_k127_2358089_1 FecR protein - - - 0.000000000000000005079 98.0
TLS3_k127_2358089_2 Sigma-70 region 2 K03088 - - 0.00000002135 65.0
TLS3_k127_2413138_0 Peptidase family M3 K01414 - 3.4.24.70 2.067e-314 985.0
TLS3_k127_2413138_1 peptidase K01415,K07386 - 3.4.24.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 557.0
TLS3_k127_2413138_2 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 488.0
TLS3_k127_2413138_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 355.0
TLS3_k127_2413138_4 isopentenyl-diphosphate delta-isomerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004774 222.0
TLS3_k127_2423401_0 Family membership - - - 0.0 1380.0
TLS3_k127_2423401_1 PFAM MscS Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 514.0
TLS3_k127_2423401_10 STAS domain K17763 - - 0.00000000000000000000000000000000000000000000000000000000003279 221.0
TLS3_k127_2423401_11 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000002669 197.0
TLS3_k127_2423401_12 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000000009536 133.0
TLS3_k127_2423401_13 cytochrome p450 - - - 0.00000000000000000000000000007276 125.0
TLS3_k127_2423401_14 peptidase - - - 0.00000000002529 73.0
TLS3_k127_2423401_15 GIY-YIG type nucleases (URI domain) K03703 - - 0.0000006001 55.0
TLS3_k127_2423401_2 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 500.0
TLS3_k127_2423401_3 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 426.0
TLS3_k127_2423401_4 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 403.0
TLS3_k127_2423401_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 377.0
TLS3_k127_2423401_6 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 322.0
TLS3_k127_2423401_7 Family membership K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000479 278.0
TLS3_k127_2423401_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001964 268.0
TLS3_k127_2423401_9 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003306 246.0
TLS3_k127_2452560_0 AAA ATPase domain - - - 0.0 1431.0
TLS3_k127_2452560_1 deoxyhypusine monooxygenase activity - - - 0.0 1315.0
TLS3_k127_2452560_10 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 365.0
TLS3_k127_2452560_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 356.0
TLS3_k127_2452560_12 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 344.0
TLS3_k127_2452560_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 293.0
TLS3_k127_2452560_14 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002678 314.0
TLS3_k127_2452560_15 PFAM Type II secretion system protein E K02669,K12203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001266 293.0
TLS3_k127_2452560_16 PFAM WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009173 278.0
TLS3_k127_2452560_17 Redoxin K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003874 250.0
TLS3_k127_2452560_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000003039 256.0
TLS3_k127_2452560_19 undecaprenyl-diphosphatase activity K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000001666 222.0
TLS3_k127_2452560_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 4.742e-222 693.0
TLS3_k127_2452560_21 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000001118 199.0
TLS3_k127_2452560_22 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000003061 181.0
TLS3_k127_2452560_23 - - - - 0.0000000000000000000000000000000000000000004858 168.0
TLS3_k127_2452560_24 YCII-related domain - - - 0.000000000000000000000000000000000000000007703 163.0
TLS3_k127_2452560_25 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000001266 107.0
TLS3_k127_2452560_26 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000118 62.0
TLS3_k127_2452560_27 peptidyl-tyrosine sulfation - - - 0.000001945 59.0
TLS3_k127_2452560_3 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 9.7e-222 698.0
TLS3_k127_2452560_4 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 495.0
TLS3_k127_2452560_5 sigma factor activity K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 465.0
TLS3_k127_2452560_6 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 394.0
TLS3_k127_2452560_7 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 381.0
TLS3_k127_2452560_8 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 377.0
TLS3_k127_2452560_9 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 362.0
TLS3_k127_245579_0 PAS fold - - - 6.886e-207 669.0
TLS3_k127_245579_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 359.0
TLS3_k127_245579_2 cheY-homologous receiver domain - - - 0.000000000000000000000005091 119.0
TLS3_k127_245579_3 Peptidoglycan-binding domain 1 protein K07126,K13582 - - 0.00000005178 57.0
TLS3_k127_2468173_0 Chalcone and stilbene synthases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 524.0
TLS3_k127_2468173_1 FAD binding domain K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 504.0
TLS3_k127_2468173_2 Diacylglycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000667 181.0
TLS3_k127_2468173_3 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000003561 82.0
TLS3_k127_2473280_0 Vault protein inter-alpha-trypsin domain - - - 0.0 1579.0
TLS3_k127_2473280_1 Domain of unknown function (DUF2088) - - - 6.695e-310 954.0
TLS3_k127_2473280_10 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000006625 256.0
TLS3_k127_2473280_11 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - 0.0000000000000000000000000000000000000000000000000000000000000001114 235.0
TLS3_k127_2473280_12 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000002816 223.0
TLS3_k127_2473280_13 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000000001263 211.0
TLS3_k127_2473280_14 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000004659 195.0
TLS3_k127_2473280_15 acetyltransferase K22441 - 2.3.1.57 0.000000000000000000000000000000000000001694 154.0
TLS3_k127_2473280_16 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000009052 143.0
TLS3_k127_2473280_18 Domain of unknown function (DUF4142) K08995 - - 0.000174 53.0
TLS3_k127_2473280_19 epimerase - - - 0.0003638 46.0
TLS3_k127_2473280_2 GGDEF domain K03412,K03413 - 3.1.1.61,3.5.1.44 3.973e-279 893.0
TLS3_k127_2473280_3 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 462.0
TLS3_k127_2473280_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 466.0
TLS3_k127_2473280_5 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 444.0
TLS3_k127_2473280_6 radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 411.0
TLS3_k127_2473280_7 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 392.0
TLS3_k127_2473280_8 transferase activity, transferring glycosyl groups K01372 - 3.4.22.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 372.0
TLS3_k127_2473280_9 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005228 276.0
TLS3_k127_2474919_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1161.0
TLS3_k127_2474919_1 lysine biosynthetic process via aminoadipic acid - - - 3.931e-301 944.0
TLS3_k127_2474919_10 Protein conserved in bacteria K09986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003217 267.0
TLS3_k127_2474919_11 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000001546 244.0
TLS3_k127_2474919_12 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000000000001878 222.0
TLS3_k127_2474919_13 ATP-dependent peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000598 213.0
TLS3_k127_2474919_17 PFAM membrane protein of K08972 - - 0.000000000001428 73.0
TLS3_k127_2474919_18 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.00006246 54.0
TLS3_k127_2474919_2 PhoD-like phosphatase K01113 - 3.1.3.1 3.469e-282 887.0
TLS3_k127_2474919_3 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 3.239e-249 777.0
TLS3_k127_2474919_4 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 374.0
TLS3_k127_2474919_5 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 385.0
TLS3_k127_2474919_6 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 361.0
TLS3_k127_2474919_7 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 362.0
TLS3_k127_2474919_8 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 322.0
TLS3_k127_2474919_9 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 308.0
TLS3_k127_2476817_0 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 305.0
TLS3_k127_2476817_1 Pentapeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000006888 254.0
TLS3_k127_2476817_2 short-chain dehydrogenase K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000001853 233.0
TLS3_k127_2487502_0 Asparagine synthase K01953 - 6.3.5.4 1.353e-307 955.0
TLS3_k127_2487502_1 Glycoside hydrolase family 44 - - - 1.158e-234 746.0
TLS3_k127_2487502_10 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 381.0
TLS3_k127_2487502_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 332.0
TLS3_k127_2487502_12 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 309.0
TLS3_k127_2487502_13 -O-antigen K02847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001797 293.0
TLS3_k127_2487502_14 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000004555 274.0
TLS3_k127_2487502_15 cytochrome C peroxidase K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000458 252.0
TLS3_k127_2487502_16 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000006696 239.0
TLS3_k127_2487502_17 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000000000000000000000000001043 207.0
TLS3_k127_2487502_18 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000001365 197.0
TLS3_k127_2487502_19 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000003556 201.0
TLS3_k127_2487502_2 HAD-superfamily phosphatase subfamily IIIC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 497.0
TLS3_k127_2487502_20 O-acyltransferase activity - - - 0.0000000000000000000000000000000000000000008526 167.0
TLS3_k127_2487502_21 polysaccharide export K01991 - - 0.000000000000000000000000000000000000000009126 161.0
TLS3_k127_2487502_22 O-acyltransferase activity K00661,K03818 GO:0003674,GO:0003824,GO:0008374,GO:0016740,GO:0016746,GO:0016747 2.3.1.79 0.00000000000000000000000000000000000002392 158.0
TLS3_k127_2487502_23 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000001203 130.0
TLS3_k127_2487502_25 Antibiotic synthesis protein MbtH K05375 - - 0.0000000000000000000000003884 108.0
TLS3_k127_2487502_26 Phage integrase family - - - 0.0000000000000000000002372 113.0
TLS3_k127_2487502_27 PFAM Bacterial transferase hexapeptide (three repeats) - - - 0.00000000000000000000338 106.0
TLS3_k127_2487502_29 O-acyltransferase activity K00661 - 2.3.1.79 0.0000000000000000001994 104.0
TLS3_k127_2487502_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 473.0
TLS3_k127_2487502_30 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000002387 93.0
TLS3_k127_2487502_31 Phosphopantetheine attachment site - - - 0.00000000000000007644 95.0
TLS3_k127_2487502_32 Signal transduction histidine kinase - - - 0.0000000000000005396 86.0
TLS3_k127_2487502_33 - - - - 0.000000000000003281 86.0
TLS3_k127_2487502_34 cheY-homologous receiver domain - - - 0.000000000000004408 80.0
TLS3_k127_2487502_35 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000001923 62.0
TLS3_k127_2487502_37 Acetyltransferase (GNAT) domain - - - 0.000003753 61.0
TLS3_k127_2487502_38 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 0.0003401 51.0
TLS3_k127_2487502_4 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 478.0
TLS3_k127_2487502_5 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 475.0
TLS3_k127_2487502_6 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 423.0
TLS3_k127_2487502_7 ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 443.0
TLS3_k127_2487502_8 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 431.0
TLS3_k127_2487502_9 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 399.0
TLS3_k127_249758_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 494.0
TLS3_k127_249758_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 374.0
TLS3_k127_249758_3 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 375.0
TLS3_k127_249758_6 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000001215 182.0
TLS3_k127_2501940_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688,K16153 - 2.4.1.1,2.4.1.11 0.0 1267.0
TLS3_k127_2501940_1 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 2.923e-279 878.0
TLS3_k127_2501940_2 PFAM Archaeal ATPase - - - 4.877e-198 656.0
TLS3_k127_2501940_3 PFAM O-antigen polymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 534.0
TLS3_k127_2501940_4 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 376.0
TLS3_k127_2501940_5 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 289.0
TLS3_k127_2501940_6 NACHT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002421 267.0
TLS3_k127_2501940_7 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000000000000000002626 222.0
TLS3_k127_2501940_8 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000009463 207.0
TLS3_k127_2501940_9 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000006059 180.0
TLS3_k127_2504108_0 E1-E2 ATPase K01533 - 3.6.3.4 7.708e-287 904.0
TLS3_k127_2504108_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.301e-213 688.0
TLS3_k127_2504108_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001012 244.0
TLS3_k127_2504108_11 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000001089 240.0
TLS3_k127_2504108_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002321 265.0
TLS3_k127_2504108_13 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000009441 211.0
TLS3_k127_2504108_14 4-vinyl reductase, 4VR - - - 0.00000000000000000000000000000000000000000000000000001798 207.0
TLS3_k127_2504108_16 STAS domain K17763 - - 0.00000000000000000000000001227 119.0
TLS3_k127_2504108_17 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000003156 106.0
TLS3_k127_2504108_18 metal cluster binding - - - 0.00000000001387 72.0
TLS3_k127_2504108_19 O-methyltransferase - - - 0.0000000001738 67.0
TLS3_k127_2504108_2 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 526.0
TLS3_k127_2504108_20 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000005461 69.0
TLS3_k127_2504108_21 PFAM PKD domain containing protein K06987 - - 0.0000001368 61.0
TLS3_k127_2504108_22 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000276 54.0
TLS3_k127_2504108_23 ligase activity, forming nitrogen-metal bonds K02230,K03403 - 6.6.1.1,6.6.1.2 0.00007414 54.0
TLS3_k127_2504108_3 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 424.0
TLS3_k127_2504108_4 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 392.0
TLS3_k127_2504108_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 373.0
TLS3_k127_2504108_6 neurogenic locus notch homolog protein K02599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 361.0
TLS3_k127_2504108_7 Protein of unknown function (DUF1595) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 353.0
TLS3_k127_2504108_8 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001963 291.0
TLS3_k127_2504108_9 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004309 266.0
TLS3_k127_2515416_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1097.0
TLS3_k127_2515416_1 Protein conserved in bacteria - - - 3.018e-238 753.0
TLS3_k127_2515416_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 6.239e-222 694.0
TLS3_k127_2515416_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 297.0
TLS3_k127_2515416_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000007959 237.0
TLS3_k127_2515416_6 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000003296 165.0
TLS3_k127_2543088_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.0 1197.0
TLS3_k127_2543088_1 Glycosyl hydrolase family 65, C-terminal domain - - - 1.758e-309 982.0
TLS3_k127_2543088_10 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007806 273.0
TLS3_k127_2543088_12 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000007674 247.0
TLS3_k127_2543088_13 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000000000000000002886 173.0
TLS3_k127_2543088_14 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001174 148.0
TLS3_k127_2543088_15 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000007288 127.0
TLS3_k127_2543088_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 4.222e-276 857.0
TLS3_k127_2543088_3 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 2.451e-219 718.0
TLS3_k127_2543088_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 548.0
TLS3_k127_2543088_5 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 507.0
TLS3_k127_2543088_6 phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 346.0
TLS3_k127_2543088_8 helix_turn_helix, Lux Regulon K02479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 292.0
TLS3_k127_2543088_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 304.0
TLS3_k127_2555731_0 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0 1022.0
TLS3_k127_2555731_1 HB1, ASXL, restriction endonuclease HTH domain - - - 1.29e-223 709.0
TLS3_k127_2555731_10 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001866 249.0
TLS3_k127_2555731_11 Thiol oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000007265 230.0
TLS3_k127_2555731_12 Thiol oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000001678 207.0
TLS3_k127_2555731_13 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000009322 155.0
TLS3_k127_2555731_14 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000007766 136.0
TLS3_k127_2555731_15 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000016 132.0
TLS3_k127_2555731_16 metallopeptidase activity - - - 0.000000000002526 79.0
TLS3_k127_2555731_17 zinc-ribbon domain - - - 0.0001059 54.0
TLS3_k127_2555731_2 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 571.0
TLS3_k127_2555731_3 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 517.0
TLS3_k127_2555731_4 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 493.0
TLS3_k127_2555731_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 467.0
TLS3_k127_2555731_6 Binding-protein-dependent transport system inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 428.0
TLS3_k127_2555731_7 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 328.0
TLS3_k127_2555731_8 amino acid activation for nonribosomal peptide biosynthetic process K20951 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003112 298.0
TLS3_k127_2555731_9 PA14 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006173 264.0
TLS3_k127_2581677_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1061.0
TLS3_k127_2581677_1 dipeptide transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 581.0
TLS3_k127_2581677_10 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000009047 229.0
TLS3_k127_2581677_11 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000004204 52.0
TLS3_k127_2581677_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 574.0
TLS3_k127_2581677_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 569.0
TLS3_k127_2581677_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 496.0
TLS3_k127_2581677_7 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 426.0
TLS3_k127_2581677_8 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 380.0
TLS3_k127_2581677_9 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 377.0
TLS3_k127_2594649_0 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 515.0
TLS3_k127_2594649_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 479.0
TLS3_k127_2594649_11 Histidine kinase HAMP K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000003827 220.0
TLS3_k127_2594649_12 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000002461 199.0
TLS3_k127_2594649_15 antisigma factor binding K17763 - - 0.000000000000000000000000000002508 137.0
TLS3_k127_2594649_17 amine dehydrogenase activity - - - 0.000000000000001647 91.0
TLS3_k127_2594649_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 468.0
TLS3_k127_2594649_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 442.0
TLS3_k127_2594649_4 Sigma-54 interaction domain K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 357.0
TLS3_k127_2594649_5 Glycosyl hydrolases family 25 K07273 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 338.0
TLS3_k127_2594649_6 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 314.0
TLS3_k127_2594649_8 Belongs to the aldehyde dehydrogenase family K00128,K00129,K04513 GO:0000302,GO:0001561,GO:0001666,GO:0003674,GO:0003824,GO:0004028,GO:0004029,GO:0004030,GO:0004033,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005777,GO:0005778,GO:0005783,GO:0005789,GO:0005829,GO:0005886,GO:0006066,GO:0006081,GO:0006082,GO:0006629,GO:0006631,GO:0006643,GO:0006665,GO:0006714,GO:0006720,GO:0006721,GO:0006805,GO:0006807,GO:0006950,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007422,GO:0007568,GO:0007584,GO:0008106,GO:0008150,GO:0008152,GO:0008284,GO:0008544,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009410,GO:0009605,GO:0009628,GO:0009719,GO:0009725,GO:0009888,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0012505,GO:0014070,GO:0014074,GO:0016020,GO:0016021,GO:0016042,GO:0016054,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016899,GO:0016903,GO:0016999,GO:0017144,GO:0018479,GO:0019395,GO:0019752,GO:0019898,GO:0030148,GO:0030258,GO:0031090,GO:0031224,GO:0031312,GO:0031667,GO:0031903,GO:0031960,GO:0031984,GO:0032501,GO:0032502,GO:0032787,GO:0033306,GO:0033993,GO:0034308,GO:0034440,GO:0036293,GO:0042127,GO:0042175,GO:0042221,GO:0042406,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046292,GO:0046395,GO:0046458,GO:0046467,GO:0046577,GO:0046683,GO:0046983,GO:0048518,GO:0048522,GO:0048545,GO:0048731,GO:0048856,GO:0050061,GO:0050789,GO:0050794,GO:0050896,GO:0051384,GO:0051591,GO:0051716,GO:0052814,GO:0055114,GO:0065007,GO:0070482,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:0072329,GO:0098588,GO:0098805,GO:0098827,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901698,GO:1901700,GO:1903173 1.2.1.3,1.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004163 308.0
TLS3_k127_2594649_9 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001533 248.0
TLS3_k127_2611426_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1399.0
TLS3_k127_2611426_1 Tetratricopeptide repeat - - - 2.544e-264 837.0
TLS3_k127_2611426_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000000007631 196.0
TLS3_k127_2611426_11 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000001947 122.0
TLS3_k127_2611426_3 His Kinase A (phosphoacceptor) domain - - - 2.267e-239 769.0
TLS3_k127_2611426_4 histidyl-tRNA synthetase K01892 - 6.1.1.21 2.086e-197 623.0
TLS3_k127_2611426_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 355.0
TLS3_k127_2611426_6 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 341.0
TLS3_k127_2611426_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004077 277.0
TLS3_k127_2611426_8 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000007269 222.0
TLS3_k127_2611426_9 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000874 196.0
TLS3_k127_2620358_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 4.364e-245 770.0
TLS3_k127_2620358_1 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 9.277e-207 653.0
TLS3_k127_2620358_10 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 291.0
TLS3_k127_2620358_11 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000217 306.0
TLS3_k127_2620358_12 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000004324 269.0
TLS3_k127_2620358_13 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.0000000000000000000000000000000000000000000000000000006999 211.0
TLS3_k127_2620358_14 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000167 183.0
TLS3_k127_2620358_16 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0008452,GO:0008664,GO:0016787,GO:0016788,GO:0016874,GO:0016886,GO:0042578,GO:0140098 3.1.4.58 0.0000000000007072 76.0
TLS3_k127_2620358_17 Cytochrome c K02305 - - 0.00000006144 67.0
TLS3_k127_2620358_2 Aminotransferase K00812 - 2.6.1.1 8.798e-196 617.0
TLS3_k127_2620358_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 611.0
TLS3_k127_2620358_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 516.0
TLS3_k127_2620358_5 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 501.0
TLS3_k127_2620358_6 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 438.0
TLS3_k127_2620358_7 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 464.0
TLS3_k127_2620358_8 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 451.0
TLS3_k127_2620358_9 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 427.0
TLS3_k127_2624922_0 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 1.304e-312 985.0
TLS3_k127_2624922_1 CBD_II K01179 - 3.2.1.4 1.062e-291 910.0
TLS3_k127_2624922_10 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 493.0
TLS3_k127_2624922_12 FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 466.0
TLS3_k127_2624922_13 Belongs to the short-chain dehydrogenases reductases (SDR) family K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 437.0
TLS3_k127_2624922_15 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 428.0
TLS3_k127_2624922_16 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 426.0
TLS3_k127_2624922_17 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 357.0
TLS3_k127_2624922_18 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 368.0
TLS3_k127_2624922_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004412 280.0
TLS3_k127_2624922_2 Involved in the tonB-independent uptake of proteins - - - 9.577e-250 783.0
TLS3_k127_2624922_20 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000978 250.0
TLS3_k127_2624922_21 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000009071 219.0
TLS3_k127_2624922_22 Protein of unknown function (DUF533) K06596 - - 0.000000000000000000000000000000000000000000000000000000003387 205.0
TLS3_k127_2624922_23 Histidine kinase K02030 - - 0.00000000000000000000000000000000000000000000000000001738 215.0
TLS3_k127_2624922_24 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000001279 186.0
TLS3_k127_2624922_25 PHP domain protein - - - 0.0000000000000000000000000002143 133.0
TLS3_k127_2624922_27 Phosphodiester glycosidase - - - 0.000000002654 68.0
TLS3_k127_2624922_3 Selenocysteine-specific translation elongation factor K03833 - - 4.076e-218 694.0
TLS3_k127_2624922_4 Ami_2 - - - 1.801e-217 691.0
TLS3_k127_2624922_5 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 600.0
TLS3_k127_2624922_6 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 570.0
TLS3_k127_2624922_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 550.0
TLS3_k127_2624922_8 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 519.0
TLS3_k127_2624922_9 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 505.0
TLS3_k127_2630932_0 peptidyl-tyrosine sulfation - - - 2.377e-298 934.0
TLS3_k127_2630932_1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 496.0
TLS3_k127_2630932_10 Domain of unknown function (DUF2341) - - - 0.00000000000000000000000000000001401 141.0
TLS3_k127_2630932_11 COG0457 FOG TPR repeat - - - 0.0000000000000000000001556 113.0
TLS3_k127_2630932_2 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 494.0
TLS3_k127_2630932_3 Enoyl-(Acyl carrier protein) reductase K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 447.0
TLS3_k127_2630932_4 PFAM TonB-dependent Receptor K16091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 452.0
TLS3_k127_2630932_5 UMP kinase activity K00947,K09903 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030151,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 302.0
TLS3_k127_2630932_6 PFAM aspartate glutamate uridylate kinase K00931,K03430,K06981 - 2.6.1.37,2.7.2.11,2.7.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 287.0
TLS3_k127_2630932_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000002651 231.0
TLS3_k127_2630932_8 transmembrane transporter activity K02008,K16783,K16785 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - 0.00000000000000000000000000000000000000001331 175.0
TLS3_k127_2630932_9 cysteine-type peptidase activity K21471 - - 0.0000000000000000000000000000000000000697 151.0
TLS3_k127_2633412_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 3.245e-268 834.0
TLS3_k127_2633412_1 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 1.397e-211 659.0
TLS3_k127_2633412_10 Zinc metalloprotease (Elastase) - - - 0.000000000000000000000000000000000000000000000000217 201.0
TLS3_k127_2633412_11 COG0534 Na -driven multidrug efflux pump - - - 0.000000000000000000000000000000000002995 158.0
TLS3_k127_2633412_12 Domain of unknown function (DUF4833) - - - 0.00000000000000000000001374 107.0
TLS3_k127_2633412_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 590.0
TLS3_k127_2633412_4 RNA-DNA hybrid ribonuclease activity K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 445.0
TLS3_k127_2633412_5 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 426.0
TLS3_k127_2633412_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 377.0
TLS3_k127_2633412_7 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 373.0
TLS3_k127_2633412_8 phosphonoacetaldehyde hydrolase activity K19270 - 3.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000008552 226.0
TLS3_k127_2633412_9 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000000000000000002454 221.0
TLS3_k127_2639939_0 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 610.0
TLS3_k127_2639939_1 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 576.0
TLS3_k127_2639939_3 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 316.0
TLS3_k127_2639939_4 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000151 188.0
TLS3_k127_2649485_0 Beta-ketoacyl synthase K12436,K15641,K16398,K16417,K20788 - - 1.546e-205 653.0
TLS3_k127_2649485_1 Thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000006658 216.0
TLS3_k127_2649485_2 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000002006 170.0
TLS3_k127_2649485_3 - - - - 0.0000000000000000000000000000000000000001032 162.0
TLS3_k127_2656534_0 protein kinase activity - - - 1.988e-213 675.0
TLS3_k127_2656534_1 COG0277 FAD FMN-containing dehydrogenases K00803 - 2.5.1.26 2.771e-207 658.0
TLS3_k127_2656534_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 427.0
TLS3_k127_2656534_3 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 407.0
TLS3_k127_2656534_4 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 361.0
TLS3_k127_2656534_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 296.0
TLS3_k127_2656534_6 Protein of unknown function (DUF3187) - - - 0.00000000000000000000000000000000000000000006017 174.0
TLS3_k127_2656534_8 Domain of unknown function (DUF4266) - - - 0.00000000000000000000009304 100.0
TLS3_k127_2656534_9 xylan catabolic process K07004 GO:0005575,GO:0005576 - 0.0000003712 55.0
TLS3_k127_266085_0 Penicillin amidase K01434 - 3.5.1.11 0.0 1143.0
TLS3_k127_266085_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 2.449e-250 784.0
TLS3_k127_266085_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001566 299.0
TLS3_k127_266085_12 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000733 199.0
TLS3_k127_266085_13 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000002491 194.0
TLS3_k127_266085_14 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000000000000000000001431 169.0
TLS3_k127_266085_15 alpha beta - - - 0.000000000000000000000000000000000000006084 159.0
TLS3_k127_266085_16 YCII-related domain K09780 - - 0.0000000000000000000000000000000000175 157.0
TLS3_k127_266085_19 - - - - 0.000004333 59.0
TLS3_k127_266085_2 domain, Protein - - - 2.413e-223 706.0
TLS3_k127_266085_3 AMP-binding enzyme C-terminal domain K18660,K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 611.0
TLS3_k127_266085_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 546.0
TLS3_k127_266085_6 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 481.0
TLS3_k127_266085_7 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 465.0
TLS3_k127_266085_8 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 355.0
TLS3_k127_266169_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0 1338.0
TLS3_k127_266169_1 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 571.0
TLS3_k127_266169_10 HAMP domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 308.0
TLS3_k127_266169_11 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 307.0
TLS3_k127_266169_12 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002781 298.0
TLS3_k127_266169_13 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000003887 243.0
TLS3_k127_266169_14 ABC-type molybdate transport system, permease component K02018 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000009233 207.0
TLS3_k127_266169_15 Putative metal-binding motif - - - 0.00000000000000000000000000000000000000000000000000000691 214.0
TLS3_k127_266169_16 ATPase activity K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000006664 191.0
TLS3_k127_266169_17 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000007446 179.0
TLS3_k127_266169_18 - - - - 0.0000000000000000000000000000000000000000000000263 181.0
TLS3_k127_266169_19 PFAM Ribulose bisphosphate carboxylase, small chain K08698 - - 0.0000000000000000000000000000000000000000000005026 190.0
TLS3_k127_266169_2 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 558.0
TLS3_k127_266169_21 - - - - 0.00000000001565 73.0
TLS3_k127_266169_3 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 568.0
TLS3_k127_266169_4 Sigma-54 interaction domain K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 539.0
TLS3_k127_266169_5 conserved protein (DUF2183) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 520.0
TLS3_k127_266169_6 Uracil phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 475.0
TLS3_k127_266169_7 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 374.0
TLS3_k127_266169_8 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 350.0
TLS3_k127_2670437_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.407e-292 904.0
TLS3_k127_2670437_1 PFAM CBS domain K03699 - - 1.808e-215 681.0
TLS3_k127_2670437_10 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 488.0
TLS3_k127_2670437_11 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 451.0
TLS3_k127_2670437_12 glutamate--cysteine ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 418.0
TLS3_k127_2670437_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 406.0
TLS3_k127_2670437_14 conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 361.0
TLS3_k127_2670437_15 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 324.0
TLS3_k127_2670437_16 PFAM CBS domain containing protein K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006142 258.0
TLS3_k127_2670437_17 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000004624 242.0
TLS3_k127_2670437_18 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001121 235.0
TLS3_k127_2670437_19 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000003523 232.0
TLS3_k127_2670437_2 Dienelactone hydrolase family K07100 - - 2.409e-210 668.0
TLS3_k127_2670437_20 Adenylylsulfate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000009493 199.0
TLS3_k127_2670437_21 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000007667 169.0
TLS3_k127_2670437_22 Universal stress protein family - - - 0.0000000000000000000000000000000000000000008839 162.0
TLS3_k127_2670437_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000632 154.0
TLS3_k127_2670437_24 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000009272 150.0
TLS3_k127_2670437_25 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000001062 152.0
TLS3_k127_2670437_26 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000002007 139.0
TLS3_k127_2670437_27 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000000102 126.0
TLS3_k127_2670437_28 - - - - 0.00000000000000000000000000006884 119.0
TLS3_k127_2670437_29 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000005137 123.0
TLS3_k127_2670437_3 Dienelactone hydrolase family K07100 - - 5.747e-209 659.0
TLS3_k127_2670437_30 Universal stress protein family - - - 0.000000000000000000003949 97.0
TLS3_k127_2670437_31 His Kinase A (phosphoacceptor) domain - - - 0.00000000002586 66.0
TLS3_k127_2670437_32 PFAM Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000001026 64.0
TLS3_k127_2670437_33 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00001242 49.0
TLS3_k127_2670437_34 Translation-initiation factor 2 K02519 - - 0.00007398 52.0
TLS3_k127_2670437_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 620.0
TLS3_k127_2670437_5 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 598.0
TLS3_k127_2670437_6 response to antibiotic K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 584.0
TLS3_k127_2670437_7 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 573.0
TLS3_k127_2670437_8 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 527.0
TLS3_k127_2670437_9 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 520.0
TLS3_k127_2672054_0 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000001128 230.0
TLS3_k127_2672054_1 Putative transposase - - - 0.000000000000000000000000000000000000000000000000000004085 207.0
TLS3_k127_2672054_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K01317 - 3.4.21.10 0.000000000000000000000000000000000000000001694 178.0
TLS3_k127_2672054_3 Putative transposase - - - 0.0000000000000000000000000000000000007324 149.0
TLS3_k127_2672054_4 Subtilase family - - - 0.00000000000000000000000000002309 136.0
TLS3_k127_2672054_5 Transposase IS66 family K07484 - - 0.000000000000000644 93.0
TLS3_k127_2672054_6 Peptidase inhibitor I9 K14645 - - 0.0000000000002538 83.0
TLS3_k127_2686690_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 616.0
TLS3_k127_2686690_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 561.0
TLS3_k127_2686690_2 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001698 274.0
TLS3_k127_2686690_3 STAS domain K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009144 254.0
TLS3_k127_2686690_4 Anti-sigma regulatory factor (Ser Thr protein kinase) K17752 - 2.7.11.1 0.00000000000000000000000000000000003046 143.0
TLS3_k127_2686690_5 transporter antisigma-factor antagonist STAS K17762 - - 0.0000000000003866 81.0
TLS3_k127_2700917_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 1571.0
TLS3_k127_2700917_1 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 372.0
TLS3_k127_2700917_2 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 305.0
TLS3_k127_2700917_3 Thioesterase domain - - - 0.00000000003359 67.0
TLS3_k127_2700917_4 phosphatidylethanolamine catabolic process K16815 GO:0000166,GO:0001516,GO:0001676,GO:0003674,GO:0003824,GO:0004620,GO:0004623,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005783,GO:0005789,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006644,GO:0006650,GO:0006690,GO:0006692,GO:0006693,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0009056,GO:0009058,GO:0009395,GO:0009987,GO:0010876,GO:0012505,GO:0015711,GO:0015718,GO:0015849,GO:0015908,GO:0015909,GO:0016020,GO:0016042,GO:0016053,GO:0016298,GO:0016787,GO:0016788,GO:0017076,GO:0019369,GO:0019637,GO:0019752,GO:0030554,GO:0031090,GO:0031903,GO:0031984,GO:0032309,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033036,GO:0033559,GO:0034638,GO:0035639,GO:0036094,GO:0036151,GO:0036152,GO:0042175,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043651,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046337,GO:0046338,GO:0046394,GO:0046434,GO:0046456,GO:0046457,GO:0046470,GO:0046475,GO:0046486,GO:0046503,GO:0046717,GO:0046903,GO:0046942,GO:0047499,GO:0050482,GO:0051179,GO:0051234,GO:0052689,GO:0071702,GO:0071704,GO:0071715,GO:0072330,GO:0097159,GO:0097164,GO:0097367,GO:0098588,GO:0098805,GO:0098827,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901571,GO:1901575,GO:1901576,GO:1903963 - 0.00003155 55.0
TLS3_k127_2700917_5 - - - - 0.0002876 48.0
TLS3_k127_2708632_0 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000000000000000000001325 213.0
TLS3_k127_2708632_1 Terpene synthase family, metal binding domain - - - 0.00000000000000000000000000000000000000000000000000003619 203.0
TLS3_k127_2709230_0 helicase superfamily c-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 595.0
TLS3_k127_2709230_2 helicase superfamily c-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 352.0
TLS3_k127_2709230_4 McrBC 5-methylcytosine restriction system component K19147 - - 0.00000000000000000000000000000000002232 140.0
TLS3_k127_2711792_0 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 598.0
TLS3_k127_2711792_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 433.0
TLS3_k127_2711792_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 394.0
TLS3_k127_2711792_3 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 377.0
TLS3_k127_2711792_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000000009939 139.0
TLS3_k127_2711792_5 Sulfatase-modifying factor enzyme 1 K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000006554 129.0
TLS3_k127_272366_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0 1013.0
TLS3_k127_272366_1 Pyridoxal-dependent decarboxylase conserved domain - - - 6.966e-200 629.0
TLS3_k127_2746145_0 BtpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 474.0
TLS3_k127_2746145_1 antisigma factor binding K04749,K20978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 347.0
TLS3_k127_2746145_10 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000004033 86.0
TLS3_k127_2746145_11 DNA-templated transcription, initiation K03088 - - 0.0000001244 57.0
TLS3_k127_2746145_2 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 305.0
TLS3_k127_2746145_3 PA14 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007952 274.0
TLS3_k127_2746145_4 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000201 256.0
TLS3_k127_2746145_5 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000108 184.0
TLS3_k127_2746145_7 family 8 K00750 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0008466,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.186 0.0000000000000000000000000000000000000003715 160.0
TLS3_k127_2746145_8 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000003107 128.0
TLS3_k127_2746145_9 Protein of unknown function (DUF1513) K09947 - - 0.0000000000000000000000000796 120.0
TLS3_k127_2747703_0 peptidyl-tyrosine sulfation K20543 - - 1.506e-211 669.0
TLS3_k127_2747703_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 532.0
TLS3_k127_2747703_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000359 289.0
TLS3_k127_2747703_12 Protein of unknown function (DUF2505) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008717 251.0
TLS3_k127_2747703_13 thioesterase K07107,K12073 - 3.1.2.28 0.000000000000000000000000000000000000000000000000003836 184.0
TLS3_k127_2747703_14 - - - - 0.0000000000000000000000000000000000001789 162.0
TLS3_k127_2747703_2 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 491.0
TLS3_k127_2747703_3 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 496.0
TLS3_k127_2747703_4 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 493.0
TLS3_k127_2747703_5 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 451.0
TLS3_k127_2747703_6 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 460.0
TLS3_k127_2747703_7 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 411.0
TLS3_k127_2747703_8 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 389.0
TLS3_k127_2747703_9 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 323.0
TLS3_k127_276818_0 Voltage gated chloride channel K03281 - - 2.307e-216 689.0
TLS3_k127_276818_1 Amino acid permease - - - 9.583e-206 661.0
TLS3_k127_276818_2 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 541.0
TLS3_k127_276818_3 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 310.0
TLS3_k127_276818_4 bacterial-type flagellum organization - - - 0.000000000000000000000000000000776 128.0
TLS3_k127_276818_5 SnoaL-like domain - - - 0.000000000004866 66.0
TLS3_k127_2768788_0 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 1.512e-206 650.0
TLS3_k127_2768788_1 Vitamin K epoxide reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 550.0
TLS3_k127_2768788_10 Transcription factor zinc-finger - - - 0.000000001237 66.0
TLS3_k127_2768788_11 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000005564 55.0
TLS3_k127_2768788_2 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 382.0
TLS3_k127_2768788_3 Putative transposase, YhgA-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 377.0
TLS3_k127_2768788_4 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 355.0
TLS3_k127_2768788_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001208 284.0
TLS3_k127_2768788_6 - - - - 0.0000000000000000000000000000000000000000000000000502 196.0
TLS3_k127_2768788_7 Castor and Pollux, part of voltage-gated ion channel - - - 0.00000000000000000000000000000000000000000001275 184.0
TLS3_k127_2768788_9 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000000002015 124.0
TLS3_k127_2772365_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1618.0
TLS3_k127_2772365_1 AAA domain K01551 - 3.6.3.16 3.228e-224 709.0
TLS3_k127_2772365_10 - - - - 0.00000000000005052 83.0
TLS3_k127_2772365_11 PFAM Thioredoxin K03671 - - 0.000000000002762 72.0
TLS3_k127_2772365_12 redox-active disulfide protein 2 - - - 0.000003394 49.0
TLS3_k127_2772365_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 389.0
TLS3_k127_2772365_3 4 iron, 4 sulfur cluster binding K00176,K00523 - 1.17.1.1,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000001374 221.0
TLS3_k127_2772365_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000000000000000001619 186.0
TLS3_k127_2772365_5 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000006766 160.0
TLS3_k127_2772365_6 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000007171 161.0
TLS3_k127_2772365_7 Arsenical resistance operon trans-acting repressor ArsD - - - 0.00000000000000000000000000000000002421 140.0
TLS3_k127_2772365_8 Sulphur transport K07112 - - 0.000000000000000000000000007341 122.0
TLS3_k127_2772365_9 Sulphur transport K07112 - - 0.000000000000000000000001232 118.0
TLS3_k127_2782735_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1187.0
TLS3_k127_2782735_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 3.405e-210 659.0
TLS3_k127_2782735_10 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005548 276.0
TLS3_k127_2782735_12 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000005405 207.0
TLS3_k127_2782735_13 Pregnancy-associated plasma protein-A K08647 - - 0.00000339 60.0
TLS3_k127_2782735_14 peptidyl-tyrosine sulfation - - - 0.000006373 49.0
TLS3_k127_2782735_2 AAA domain - - - 2.701e-202 638.0
TLS3_k127_2782735_3 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 563.0
TLS3_k127_2782735_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 533.0
TLS3_k127_2782735_5 protein kinase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 381.0
TLS3_k127_2782735_6 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 364.0
TLS3_k127_2782735_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 321.0
TLS3_k127_2782735_8 Bacterial pre-peptidase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 327.0
TLS3_k127_2782735_9 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001754 294.0
TLS3_k127_2790929_0 4Fe-4S single cluster domain K06937 - - 0.0 1086.0
TLS3_k127_2790929_1 deoxyhypusine monooxygenase activity K01932 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 563.0
TLS3_k127_2790929_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 514.0
TLS3_k127_2790929_3 glutathione transferase activity K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000209 275.0
TLS3_k127_2790929_4 skeletal muscle myosin thick filament assembly K00907,K12567 GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008092,GO:0030016,GO:0030017,GO:0031674,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0044877,GO:0051015,GO:0099080,GO:0099081,GO:0099512 2.7.11.1,2.7.11.18 0.0000671 52.0
TLS3_k127_2793270_0 Uncharacterised protein family (UPF0182) K09118 - - 3.318e-240 752.0
TLS3_k127_2793270_1 Sodium/hydrogen exchanger family K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 510.0
TLS3_k127_2793270_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000007525 164.0
TLS3_k127_2793270_3 Multisubunit Na H antiporter MnhC subunit K05567 - - 0.000000000002945 68.0
TLS3_k127_2797837_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 5.3e-221 694.0
TLS3_k127_2797837_1 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 504.0
TLS3_k127_2797837_2 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 496.0
TLS3_k127_2797837_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 422.0
TLS3_k127_2797837_4 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 318.0
TLS3_k127_2797837_5 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004258 263.0
TLS3_k127_2797837_6 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000005241 182.0
TLS3_k127_2797837_8 transcriptional regulator - - - 0.0000000000000000000000000000002389 137.0
TLS3_k127_280336_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0 1124.0
TLS3_k127_280336_1 protein involved in exopolysaccharide biosynthesis K16554 - - 1.323e-285 898.0
TLS3_k127_280336_2 Belongs to the thiolase family K00626 - 2.3.1.9 3.407e-194 614.0
TLS3_k127_280336_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 479.0
TLS3_k127_280336_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 376.0
TLS3_k127_280336_5 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 365.0
TLS3_k127_280336_6 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002701 267.0
TLS3_k127_280336_7 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000000002026 180.0
TLS3_k127_280336_8 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000000009322 155.0
TLS3_k127_2807624_0 - - - - 1.958e-271 856.0
TLS3_k127_2807624_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 480.0
TLS3_k127_2807624_12 Uncharacterized protein conserved in bacteria (DUF2171) - - - 0.00000000000000000000000000008206 117.0
TLS3_k127_2807624_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000004307 98.0
TLS3_k127_2807624_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 460.0
TLS3_k127_2807624_3 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 406.0
TLS3_k127_2807624_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 340.0
TLS3_k127_2807624_5 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 351.0
TLS3_k127_2807624_6 phosphoglycolate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 340.0
TLS3_k127_2807624_8 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006634 235.0
TLS3_k127_2807624_9 Rhs family - - - 0.0000000000000000000000000000000000007219 148.0
TLS3_k127_2807819_0 - - - - 2.087e-249 787.0
TLS3_k127_2807819_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 495.0
TLS3_k127_2807819_10 Rhs family - - - 0.0000000000000000000000000000009708 125.0
TLS3_k127_2807819_2 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 494.0
TLS3_k127_2807819_3 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 404.0
TLS3_k127_2807819_4 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 392.0
TLS3_k127_2807819_5 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000347 236.0
TLS3_k127_2807819_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000007297 225.0
TLS3_k127_2807819_7 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000001289 196.0
TLS3_k127_2807819_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000008014 156.0
TLS3_k127_2807819_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000009509 141.0
TLS3_k127_2835316_0 Class II Aldolase and Adducin N-terminal domain - - - 2.092e-273 856.0
TLS3_k127_2835316_1 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 369.0
TLS3_k127_2835316_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000007216 233.0
TLS3_k127_2835316_3 Protein of unknown function (DUF3089) - - - 0.00000000000000000000000000000000000000000000000000000001286 213.0
TLS3_k127_2835316_4 - - - - 0.0000000000000000000000000000000000000000000001319 172.0
TLS3_k127_2835316_5 Belongs to the glutathione peroxidase family K00432,K20207 - 1.11.1.22,1.11.1.9 0.00000000000000000000000000000000009896 142.0
TLS3_k127_2835316_6 - - - - 0.000000000000000003354 86.0
TLS3_k127_2848543_0 Family membership - - - 0.0 2084.0
TLS3_k127_2848543_1 Family membership K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 333.0
TLS3_k127_2848543_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000331 264.0
TLS3_k127_2848543_3 Protein of unknown function (DUF3703) - - - 0.000000000000000000000000000000000000000000000001607 177.0
TLS3_k127_2848543_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000455 167.0
TLS3_k127_2848543_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000008333 139.0
TLS3_k127_2848543_7 Transcriptional regulator, AraC family - - - 0.000000000000000000000000000001919 126.0
TLS3_k127_2848543_9 Flagellar Motor Protein K11892 - - 0.0002839 44.0
TLS3_k127_2854901_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 529.0
TLS3_k127_2854901_1 FAD binding domain K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 510.0
TLS3_k127_2854901_10 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002739 246.0
TLS3_k127_2854901_11 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000004375 240.0
TLS3_k127_2854901_14 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000001267 181.0
TLS3_k127_2854901_15 Von willebrand factor, type a - - - 0.000000000000000000000000000000000000001175 166.0
TLS3_k127_2854901_16 Universal stress protein family - - - 0.0000000000000000000000000000000001775 139.0
TLS3_k127_2854901_18 AI-2E family transporter - - - 0.000000000000000000000000001672 126.0
TLS3_k127_2854901_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 511.0
TLS3_k127_2854901_21 SERine Proteinase INhibitors K13963 - - 0.0000002636 56.0
TLS3_k127_2854901_22 - - - - 0.00001482 52.0
TLS3_k127_2854901_23 protein kinase activity - - - 0.0008015 48.0
TLS3_k127_2854901_24 PFAM blue (type 1) copper domain protein - - - 0.0008517 51.0
TLS3_k127_2854901_3 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 431.0
TLS3_k127_2854901_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 406.0
TLS3_k127_2854901_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 364.0
TLS3_k127_2854901_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 348.0
TLS3_k127_2854901_8 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 324.0
TLS3_k127_2867230_0 Alpha-2-Macroglobulin K06894 - - 0.0 2250.0
TLS3_k127_2867230_1 Transglycosylase K05367 - 2.4.1.129 3.113e-317 990.0
TLS3_k127_2867230_10 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008469 284.0
TLS3_k127_2867230_12 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000001111 133.0
TLS3_k127_2867230_14 oxidoreductase activity K07114 - - 0.00000000002873 65.0
TLS3_k127_2867230_2 ABC-type uncharacterized transport system - - - 3.67e-235 755.0
TLS3_k127_2867230_3 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 599.0
TLS3_k127_2867230_4 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 461.0
TLS3_k127_2867230_5 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 434.0
TLS3_k127_2867230_6 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 385.0
TLS3_k127_2867230_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 372.0
TLS3_k127_2867230_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 378.0
TLS3_k127_2867230_9 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 338.0
TLS3_k127_2889096_0 COG0553 Superfamily II DNA RNA - - - 1.321e-216 706.0
TLS3_k127_2889096_1 Transcriptional regulator K12146,K15836 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 404.0
TLS3_k127_2889096_2 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 381.0
TLS3_k127_2889096_3 cell envelope organization K05807,K08309 - - 0.0000000000000000000000000000000000000000000000000000000007081 218.0
TLS3_k127_2889096_4 - - - - 0.000000000000000000000000000000001208 147.0
TLS3_k127_2889096_5 Putative metal-binding motif - - - 0.000000000002716 76.0
TLS3_k127_2889096_6 Trypsin-like serine protease - - - 0.000002085 59.0
TLS3_k127_2889096_7 amine dehydrogenase activity - - - 0.0001661 52.0
TLS3_k127_2889096_8 PFAM blue (type 1) copper domain protein - - - 0.0002529 53.0
TLS3_k127_2899881_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 557.0
TLS3_k127_2899881_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 534.0
TLS3_k127_2908709_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 448.0
TLS3_k127_2908709_1 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004772 283.0
TLS3_k127_2908709_2 - - - - 0.0000000000000000000000000000000000000000000000000007469 196.0
TLS3_k127_2908709_3 tRNA binding K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000008879 166.0
TLS3_k127_2915110_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1309.0
TLS3_k127_2915110_1 aconitate hydratase K01681 - 4.2.1.3 1.473e-308 958.0
TLS3_k127_2915110_10 PEGA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 323.0
TLS3_k127_2915110_11 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000001372 214.0
TLS3_k127_2915110_12 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000000000000000000000149 209.0
TLS3_k127_2915110_13 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000000000904 203.0
TLS3_k127_2915110_14 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000001931 186.0
TLS3_k127_2915110_2 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 1.367e-247 770.0
TLS3_k127_2915110_3 Flagellar Motor Protein - - - 4.647e-246 779.0
TLS3_k127_2915110_4 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 615.0
TLS3_k127_2915110_5 phosphorelay signal transduction system K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 581.0
TLS3_k127_2915110_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 533.0
TLS3_k127_2915110_7 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 479.0
TLS3_k127_2915110_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 347.0
TLS3_k127_29301_0 Glycosyl hydrolases family 16 - - - 5.094e-244 761.0
TLS3_k127_29301_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 579.0
TLS3_k127_29301_10 Domain of unknown function (DUF4215) - - - 0.000000000000001526 91.0
TLS3_k127_29301_11 Domain of unknown function (DUF362) - - - 0.00000000006672 74.0
TLS3_k127_29301_2 Dihydroxyacetone kinase K00863 - 2.7.1.28,2.7.1.29,4.6.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 557.0
TLS3_k127_29301_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007727 449.0
TLS3_k127_29301_4 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 391.0
TLS3_k127_29301_5 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 329.0
TLS3_k127_29301_6 COG1024 Enoyl-CoA hydratase carnithine racemase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000004509 205.0
TLS3_k127_29301_7 membrane protein (homolog of Drosophila rhomboid) - - - 0.00000000000000000000000000000000001191 145.0
TLS3_k127_29301_8 - - - - 0.0000000000000000000003481 103.0
TLS3_k127_29301_9 asparagine K01953 - 6.3.5.4 0.00000000000000000003962 106.0
TLS3_k127_2940615_0 Phage tail sheath C-terminal domain K06907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 520.0
TLS3_k127_2940615_1 Phage tail sheath protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002084 281.0
TLS3_k127_2940615_2 Phage protein D - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001843 259.0
TLS3_k127_2940615_3 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000007093 210.0
TLS3_k127_2940615_4 Flagellar Assembly Protein A - - - 0.00000000000000000000000000000000000000000000000000004855 204.0
TLS3_k127_2940615_5 phage tail region protein - - - 0.00000000000000000000000000000000000000004174 158.0
TLS3_k127_2940615_6 Protein of unknown function (DUF4255) - - - 0.00000000000000000008021 96.0
TLS3_k127_2963_0 Heat shock 70 kDa protein K04043 - - 0.0 1012.0
TLS3_k127_2963_1 Putative glutamine amidotransferase - - - 2.192e-303 949.0
TLS3_k127_2963_10 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004317 263.0
TLS3_k127_2963_11 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006293 259.0
TLS3_k127_2963_12 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000001674 205.0
TLS3_k127_2963_13 diguanylate cyclase activity - - - 0.0000000000000000000000000000000000000004888 151.0
TLS3_k127_2963_14 - - - - 0.000000000000000000000000001383 129.0
TLS3_k127_2963_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 7.432e-232 725.0
TLS3_k127_2963_3 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 5.768e-227 723.0
TLS3_k127_2963_4 ATPase involved in DNA repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 468.0
TLS3_k127_2963_6 N-terminal double-transmembrane domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 368.0
TLS3_k127_2963_7 member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins - GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050308 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 322.0
TLS3_k127_2963_8 FHA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001418 277.0
TLS3_k127_2970748_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 1.338e-313 972.0
TLS3_k127_2970748_1 Sodium/hydrogen exchanger family K03455,K11745,K11747 - - 4.821e-199 639.0
TLS3_k127_2970748_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 411.0
TLS3_k127_2970748_3 NADPH-quinone reductase (modulator of drug activity B) K00355,K11746,K11748 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000001022 203.0
TLS3_k127_2970748_4 CAAX protease self-immunity - - - 0.0000000000000002046 90.0
TLS3_k127_2996894_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2629.0
TLS3_k127_2996894_1 Domain of unknown function (DUF362) - - - 7.213e-267 830.0
TLS3_k127_2996894_10 endonuclease activity K07451 - - 0.000000000000000000000000000000000000000000000000000000000002305 217.0
TLS3_k127_2996894_11 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000005489 204.0
TLS3_k127_2996894_12 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000001143 159.0
TLS3_k127_2996894_13 - - - - 0.00000000000000000000000000001078 127.0
TLS3_k127_2996894_14 amine dehydrogenase activity - - - 0.00000000000009573 83.0
TLS3_k127_2996894_16 CHAP domain - - - 0.00002664 56.0
TLS3_k127_2996894_17 - - - - 0.0001317 53.0
TLS3_k127_2996894_2 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 1.277e-211 662.0
TLS3_k127_2996894_3 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 617.0
TLS3_k127_2996894_4 Domain of unknown function (DUF4091) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 530.0
TLS3_k127_2996894_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 293.0
TLS3_k127_2996894_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001424 275.0
TLS3_k127_2996894_8 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000007745 228.0
TLS3_k127_2996894_9 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000004911 228.0
TLS3_k127_3001589_0 Cytochrome c554 and c-prime - - - 0.0 1271.0
TLS3_k127_3001589_1 4Fe-4S dicluster domain - - - 5.038e-296 937.0
TLS3_k127_3001589_10 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 489.0
TLS3_k127_3001589_11 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 462.0
TLS3_k127_3001589_12 Diacylglycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 439.0
TLS3_k127_3001589_13 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 387.0
TLS3_k127_3001589_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 370.0
TLS3_k127_3001589_15 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 353.0
TLS3_k127_3001589_16 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 357.0
TLS3_k127_3001589_17 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 342.0
TLS3_k127_3001589_18 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 340.0
TLS3_k127_3001589_19 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001543 294.0
TLS3_k127_3001589_2 ABC transporter, ATP-binding protein - - - 7.894e-294 910.0
TLS3_k127_3001589_20 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003305 266.0
TLS3_k127_3001589_21 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000004194 263.0
TLS3_k127_3001589_22 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000001499 241.0
TLS3_k127_3001589_24 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000000000000000002506 227.0
TLS3_k127_3001589_25 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000000007935 222.0
TLS3_k127_3001589_26 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000005528 212.0
TLS3_k127_3001589_28 PFAM Roadblock LC7 family protein K07131 - - 0.000000000000000004891 91.0
TLS3_k127_3001589_29 - - - - 0.00000001124 63.0
TLS3_k127_3001589_3 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 3.084e-271 854.0
TLS3_k127_3001589_4 Pyridine nucleotide-disulphide oxidoreductase - - - 1.254e-250 829.0
TLS3_k127_3001589_5 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.807e-237 741.0
TLS3_k127_3001589_6 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 2.273e-216 700.0
TLS3_k127_3001589_8 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 539.0
TLS3_k127_3001589_9 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 523.0
TLS3_k127_3011613_0 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 484.0
TLS3_k127_3011613_1 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 441.0
TLS3_k127_3011613_2 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 427.0
TLS3_k127_3011613_3 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 325.0
TLS3_k127_3011613_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000002563 220.0
TLS3_k127_3011613_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000242 216.0
TLS3_k127_3011613_7 Belongs to the BolA IbaG family K05527,K22066 - - 0.0000000000000000000000000000000000000003317 151.0
TLS3_k127_3011613_8 - - - - 0.0000000000000000000000000000000000000006214 160.0
TLS3_k127_3036130_0 High confidence in function and specificity - - - 2.267e-264 839.0
TLS3_k127_3036130_1 Peptidase family M13 K01415,K07386 - 3.4.24.71 6.65e-259 816.0
TLS3_k127_3036130_10 helix_turn_helix, arabinose operon control protein - - - 0.000000000002812 73.0
TLS3_k127_3036130_11 - - - - 0.00002766 52.0
TLS3_k127_3036130_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 536.0
TLS3_k127_3036130_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 522.0
TLS3_k127_3036130_4 response regulator receiver K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 333.0
TLS3_k127_3036130_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002411 285.0
TLS3_k127_3036130_6 PFAM CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000002022 159.0
TLS3_k127_3036130_7 - - - - 0.0000000000000000000000000000001829 134.0
TLS3_k127_3036130_8 - - - - 0.0000000000000000000000000001045 130.0
TLS3_k127_3036130_9 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000003027 75.0
TLS3_k127_3047197_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1058.0
TLS3_k127_3047197_1 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 441.0
TLS3_k127_3047197_2 FecR protein - - - 0.000000000000000000000000000001792 124.0
TLS3_k127_3064472_0 - - - - 2.705e-231 732.0
TLS3_k127_3064472_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.347e-222 721.0
TLS3_k127_3064472_11 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 290.0
TLS3_k127_3064472_13 - - - - 0.0000000000000000000000000000000000000000000000022 182.0
TLS3_k127_3064472_17 Calcium-binding EGF-like domain - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.0000003997 62.0
TLS3_k127_3064472_18 Esterase PHB depolymerase - - - 0.0001262 55.0
TLS3_k127_3064472_2 Response regulator, receiver K02488,K07719 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 554.0
TLS3_k127_3064472_3 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 554.0
TLS3_k127_3064472_4 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 511.0
TLS3_k127_3064472_5 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 456.0
TLS3_k127_3064472_6 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 443.0
TLS3_k127_3064472_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 456.0
TLS3_k127_3064472_8 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 375.0
TLS3_k127_3064472_9 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 329.0
TLS3_k127_3083738_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 440.0
TLS3_k127_3083738_1 NmrA-like family K19267 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 295.0
TLS3_k127_3083738_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000004146 287.0
TLS3_k127_3083738_3 Transposase - - - 0.0000000000000548 85.0
TLS3_k127_3083738_4 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000648 65.0
TLS3_k127_3089246_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000003149 240.0
TLS3_k127_3089246_1 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000001634 199.0
TLS3_k127_3091162_0 SMART Elongator protein 3 MiaB NifB - - - 0.0 1409.0
TLS3_k127_3091162_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000003655 228.0
TLS3_k127_3091162_3 - - - - 0.000000000000000000000000000000000000000000000002687 187.0
TLS3_k127_30964_0 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 590.0
TLS3_k127_30964_1 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 529.0
TLS3_k127_30964_11 protein transport across the cell outer membrane - - - 0.00000000000000000000000000000000008528 147.0
TLS3_k127_30964_12 DNA-binding protein VF530 - GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000003033 115.0
TLS3_k127_30964_2 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 485.0
TLS3_k127_30964_3 chlorophyll binding K16191,K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 445.0
TLS3_k127_30964_6 Major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 369.0
TLS3_k127_30964_7 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 314.0
TLS3_k127_30964_8 Cytochrome c K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002487 263.0
TLS3_k127_30964_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001159 257.0
TLS3_k127_3126929_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.082e-238 746.0
TLS3_k127_3126929_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 3.052e-237 740.0
TLS3_k127_3126929_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 3.739e-225 704.0
TLS3_k127_3126929_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 369.0
TLS3_k127_3126929_5 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000000000000000000000000000000000000000000000000003526 207.0
TLS3_k127_3126929_6 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000004761 165.0
TLS3_k127_3148331_0 bacterial-type flagellum organization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 408.0
TLS3_k127_3148331_1 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 320.0
TLS3_k127_3148331_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000003964 220.0
TLS3_k127_3148331_6 Amidinotransferase K01478 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0008218,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.6 0.0000000000000000000000000000000000000000008722 181.0
TLS3_k127_3148331_7 PFAM amidinotransferase K01478 - 3.5.3.6 0.0000000000000003185 93.0
TLS3_k127_3148331_9 Calcium ion binding - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.00001322 57.0
TLS3_k127_3153501_0 Multicopper oxidase K08100 - 1.3.3.5 1.308e-250 788.0
TLS3_k127_3153501_1 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 9.957e-235 764.0
TLS3_k127_3153501_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K02585,K03639,K05879 - 2.7.1.121,4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 466.0
TLS3_k127_3153501_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 306.0
TLS3_k127_3158539_0 protein conserved in bacteria K11904 - - 0.0 1021.0
TLS3_k127_3158539_1 Conserved repeat domain - - - 1.893e-287 908.0
TLS3_k127_3158539_10 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004209 297.0
TLS3_k127_3158539_13 Domain of unknown function (DUF4123) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000727 259.0
TLS3_k127_3158539_14 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000879 233.0
TLS3_k127_3158539_16 PAAR motif - - - 0.0000000000000000000000000000000000000000000007053 177.0
TLS3_k127_3158539_18 B-1 B cell differentiation - - - 0.0000000000000000000003196 111.0
TLS3_k127_3158539_19 FIST C domain - GO:0008150,GO:0040007 - 0.000000000001703 69.0
TLS3_k127_3158539_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 5.159e-273 846.0
TLS3_k127_3158539_20 - - - - 0.0000000002838 66.0
TLS3_k127_3158539_3 protein conserved in bacteria K11904 - - 1.52e-258 826.0
TLS3_k127_3158539_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 1.303e-194 616.0
TLS3_k127_3158539_5 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 564.0
TLS3_k127_3158539_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 509.0
TLS3_k127_3158539_7 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 364.0
TLS3_k127_3158539_8 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 314.0
TLS3_k127_3158539_9 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001337 292.0
TLS3_k127_3208724_0 protein conserved in bacteria K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 483.0
TLS3_k127_3208724_1 alpha/beta hydrolase fold K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 424.0
TLS3_k127_3208724_11 - - - - 0.00001096 55.0
TLS3_k127_3208724_13 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0005763 44.0
TLS3_k127_3208724_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000003663 241.0
TLS3_k127_3208724_3 Collagen triple helix repeat (20 copies) - - - 0.0000000000000000000000000000000000000000000002896 175.0
TLS3_k127_3208724_4 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000000000000002156 183.0
TLS3_k127_3208724_5 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000009481 171.0
TLS3_k127_3208724_6 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000001175 159.0
TLS3_k127_3208724_7 ASPIC and UnbV - - - 0.000000000000000000000000000000006344 147.0
TLS3_k127_3208724_9 FecR protein - - - 0.000000000000000000000000009453 124.0
TLS3_k127_3214924_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 5.544e-317 977.0
TLS3_k127_3214924_1 Sulfatase-modifying factor enzyme 1 - - - 3.515e-230 739.0
TLS3_k127_3214924_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001783 222.0
TLS3_k127_3214924_11 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000001358 213.0
TLS3_k127_3214924_12 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000009569 187.0
TLS3_k127_3214924_13 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000002205 179.0
TLS3_k127_3214924_14 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17762 - - 0.00000000000000000000000000000000000000000001572 167.0
TLS3_k127_3214924_15 Histidine kinase-like ATPases K17752 - 2.7.11.1 0.0000000000000000000000000000000000000448 151.0
TLS3_k127_3214924_16 Rubredoxin - - - 0.00000000000000000002871 95.0
TLS3_k127_3214924_17 Caspase domain - - - 0.000000000007145 78.0
TLS3_k127_3214924_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.561e-205 656.0
TLS3_k127_3214924_4 denitrification pathway - - - 6.423e-195 626.0
TLS3_k127_3214924_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 593.0
TLS3_k127_3214924_6 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 482.0
TLS3_k127_3214924_7 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 328.0
TLS3_k127_3214924_8 STAS domain K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 308.0
TLS3_k127_3214924_9 FHA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 303.0
TLS3_k127_322744_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 7.023e-277 857.0
TLS3_k127_322744_1 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 599.0
TLS3_k127_322744_2 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 413.0
TLS3_k127_322744_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 385.0
TLS3_k127_322744_5 - - - - 0.000002053 59.0
TLS3_k127_3229618_0 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 324.0
TLS3_k127_3229618_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008129 258.0
TLS3_k127_3229618_2 PFAM regulatory protein TetR - - - 0.00000000000000000000000008992 114.0
TLS3_k127_3229618_4 Belongs to the 'phage' integrase family - - - 0.0000000000000006539 85.0
TLS3_k127_3229618_5 FRG - - - 0.000000000002695 71.0
TLS3_k127_3240549_0 response regulator K02481,K07713 - - 1.577e-220 691.0
TLS3_k127_3240549_1 Protoglobin - - - 3.896e-210 667.0
TLS3_k127_3240549_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009864 267.0
TLS3_k127_3240549_11 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000759 261.0
TLS3_k127_3240549_13 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000000000000000000002476 240.0
TLS3_k127_3240549_14 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000025 240.0
TLS3_k127_3240549_15 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000002945 193.0
TLS3_k127_3240549_16 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000004132 189.0
TLS3_k127_3240549_17 AMP binding - - - 0.000000000000000000000000000000000000183 146.0
TLS3_k127_3240549_2 VWA domain containing CoxE-like protein K09989 - - 3.927e-201 632.0
TLS3_k127_3240549_21 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000005548 51.0
TLS3_k127_3240549_22 - - - - 0.000006171 60.0
TLS3_k127_3240549_3 prohibitin homologues K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 557.0
TLS3_k127_3240549_4 prohibitin homologues K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000944 570.0
TLS3_k127_3240549_5 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 490.0
TLS3_k127_3240549_6 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 486.0
TLS3_k127_3240549_7 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 439.0
TLS3_k127_3240549_8 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 306.0
TLS3_k127_3240549_9 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002631 278.0
TLS3_k127_3250054_0 Domain of unknown function (DUF362) - - - 3.424e-255 791.0
TLS3_k127_3250054_1 AAA domain (dynein-related subfamily) K03924 - - 1.367e-215 683.0
TLS3_k127_3250054_2 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 400.0
TLS3_k127_3250054_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 348.0
TLS3_k127_3250054_4 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000008766 202.0
TLS3_k127_3250054_5 Transglutaminase-like superfamily - - - 0.000000000000000000004956 106.0
TLS3_k127_3250054_6 Predicted membrane protein (DUF2079) - - - 0.0000000000000000001262 103.0
TLS3_k127_3250374_0 oxidoreductase activity K07114 - - 0.0 1642.0
TLS3_k127_3250374_1 oxidoreductase activity K07114 - - 0.0 1562.0
TLS3_k127_3250374_2 Thioredoxin - - - 5.835e-312 969.0
TLS3_k127_3250374_3 Protein kinase; unclassified specificity. K12132 - 2.7.11.1 2.334e-283 893.0
TLS3_k127_3250374_4 Belongs to the ompA family K20276 - - 2.889e-249 796.0
TLS3_k127_3250374_5 - - - - 1.258e-247 787.0
TLS3_k127_3250374_6 drug transmembrane transporter activity K03327 - - 5.238e-229 717.0
TLS3_k127_3250374_7 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 357.0
TLS3_k127_3250374_9 amino acid activation for nonribosomal peptide biosynthetic process K20276 - - 0.000000000000000000002099 110.0
TLS3_k127_3255654_0 Belongs to the heat shock protein 70 family - - - 0.0 1267.0
TLS3_k127_3255654_1 MreB/Mbl protein - - - 1.208e-311 965.0
TLS3_k127_3255654_2 Rieske 2Fe2S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 451.0
TLS3_k127_3255654_3 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 336.0
TLS3_k127_3255654_4 Squalene/phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000006209 253.0
TLS3_k127_3255654_5 Domain of unknown function (DUF2760) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006333 237.0
TLS3_k127_3255654_6 Squalene epoxidase K00511 - 1.14.14.17 0.0000000000000000000000000000000000000000000000000000005519 210.0
TLS3_k127_3255654_8 Squalene cyclase K01852 - 5.4.99.7 0.000000000000000000000000000000000000009357 153.0
TLS3_k127_3283948_0 Belongs to the ompA family - - - 8.587e-272 851.0
TLS3_k127_3283948_1 Amidase - - - 6.74e-250 788.0
TLS3_k127_3283948_10 Domain of unknown function (DUF4291) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003315 265.0
TLS3_k127_3283948_11 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.00000000000000000000000000000000000005273 164.0
TLS3_k127_3283948_12 NmrA-like family - - - 0.0000000000000000000000000001015 124.0
TLS3_k127_3283948_13 helicase K03722 - 3.6.4.12 0.000000000001094 68.0
TLS3_k127_3283948_14 SMART AAA ATPase - - - 0.0000000005209 61.0
TLS3_k127_3283948_3 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 385.0
TLS3_k127_3283948_4 Lanthionine synthetase C-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 362.0
TLS3_k127_3283948_5 Uncharacterized protein conserved in bacteria (DUF2263) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 349.0
TLS3_k127_3283948_6 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 365.0
TLS3_k127_3283948_7 COGs COG4325 membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 330.0
TLS3_k127_3283948_8 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 315.0
TLS3_k127_3283948_9 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009024 274.0
TLS3_k127_3291423_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.949e-228 712.0
TLS3_k127_3291423_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 492.0
TLS3_k127_3291423_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 415.0
TLS3_k127_3291423_3 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 403.0
TLS3_k127_3291423_5 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 330.0
TLS3_k127_3291423_6 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 317.0
TLS3_k127_3291423_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000007888 267.0
TLS3_k127_3291423_8 Tetratricopeptide repeat - - - 0.000000003682 67.0
TLS3_k127_3308847_0 protein conserved in bacteria K11904 - - 2.486e-215 675.0
TLS3_k127_3308847_1 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 405.0
TLS3_k127_3308847_3 S-layer homology domain - - - 0.00000000000000000000008451 115.0
TLS3_k127_3327205_0 polyketide synthase K04786 - - 0.0 1245.0
TLS3_k127_3327205_1 Family membership - - - 1.595e-200 640.0
TLS3_k127_3332937_0 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 349.0
TLS3_k127_3332937_1 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000006669 247.0
TLS3_k127_3332937_2 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000001746 220.0
TLS3_k127_3332937_3 NUDIX hydrolase - - - 0.0000000000000002401 80.0
TLS3_k127_3349741_0 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 535.0
TLS3_k127_3349741_2 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 376.0
TLS3_k127_3349741_3 cell envelope organization K05807,K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 364.0
TLS3_k127_3349741_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 361.0
TLS3_k127_3349741_5 tRNA cytidylyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002015 270.0
TLS3_k127_3349741_7 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000004132 225.0
TLS3_k127_3356740_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1305.0
TLS3_k127_3356740_1 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 376.0
TLS3_k127_3356740_2 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.00000000000000000000000000000000000000000000000003556 183.0
TLS3_k127_3365512_0 Protein export membrane protein K03296,K18138 - - 0.0 1208.0
TLS3_k127_3365512_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 4.753e-235 742.0
TLS3_k127_3365512_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 356.0
TLS3_k127_3365512_3 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 329.0
TLS3_k127_3365512_4 transcriptional regulator - - - 0.0000000000000000000000002813 112.0
TLS3_k127_3365512_5 - - - - 0.000000000003472 76.0
TLS3_k127_3372280_0 Predicted AAA-ATPase - - - 3.681e-221 701.0
TLS3_k127_3372280_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 507.0
TLS3_k127_3372280_2 PFAM Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 336.0
TLS3_k127_3372280_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000003638 234.0
TLS3_k127_3375002_0 Carboxyl transferase domain - - - 2.557e-285 881.0
TLS3_k127_3375002_1 Subtilase family - - - 3.843e-270 857.0
TLS3_k127_3375002_10 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000002684 59.0
TLS3_k127_3375002_2 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 408.0
TLS3_k127_3375002_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 305.0
TLS3_k127_3375002_4 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 291.0
TLS3_k127_3375002_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001097 284.0
TLS3_k127_3375002_6 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007448 264.0
TLS3_k127_3375002_7 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 234.0
TLS3_k127_3375002_8 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000003304 232.0
TLS3_k127_3375002_9 Transcription elongation factor, GreA/GreB, C-term - - - 0.0000000000000000000000000003253 120.0
TLS3_k127_3377884_0 protein conserved in bacteria K11891 - - 0.0 1166.0
TLS3_k127_3377884_1 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 481.0
TLS3_k127_3377884_2 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 343.0
TLS3_k127_3377884_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000008423 220.0
TLS3_k127_3377884_4 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000001451 193.0
TLS3_k127_3377884_5 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000002287 188.0
TLS3_k127_3377884_6 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000001096 130.0
TLS3_k127_3396754_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0 1089.0
TLS3_k127_3396754_1 TIGRFAM phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 1.291e-315 974.0
TLS3_k127_3396754_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 446.0
TLS3_k127_3396754_13 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 349.0
TLS3_k127_3396754_14 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 344.0
TLS3_k127_3396754_15 MobA-like NTP transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 335.0
TLS3_k127_3396754_17 PFAM thiamine pyrophosphate protein domain protein TPP-binding K09459 - 4.1.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005097 276.0
TLS3_k127_3396754_18 Sulfopyruvate decarboxylase K06034,K09459 - 4.1.1.79,4.1.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008155 266.0
TLS3_k127_3396754_19 Putative bacterial sensory transduction regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002313 252.0
TLS3_k127_3396754_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 3.546e-220 693.0
TLS3_k127_3396754_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000001181 248.0
TLS3_k127_3396754_21 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000001557 243.0
TLS3_k127_3396754_22 Domain of unknown function (DUF4331) - - - 0.000000000000000000000000000000000000000000000000000000006013 208.0
TLS3_k127_3396754_26 snoRNA binding - - - 0.000000000000000000000000000000000000000007669 166.0
TLS3_k127_3396754_28 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564 3.4.21.102 0.000000000000000000000000000000002376 134.0
TLS3_k127_3396754_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.257e-219 687.0
TLS3_k127_3396754_30 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000832 129.0
TLS3_k127_3396754_31 Ferredoxin K04755,K11107 - - 0.0000000000000000000000004023 113.0
TLS3_k127_3396754_33 Family of unknown function (DUF5339) - - - 0.0000302 55.0
TLS3_k127_3396754_4 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 8.303e-215 671.0
TLS3_k127_3396754_5 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 8.925e-208 656.0
TLS3_k127_3396754_6 Transcriptional regulator - - - 6.194e-204 652.0
TLS3_k127_3396754_7 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 495.0
TLS3_k127_3396754_8 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 511.0
TLS3_k127_3396754_9 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 490.0
TLS3_k127_3414779_0 Heat shock 70 kDa protein K04043,K04045 - - 3.765e-224 710.0
TLS3_k127_3414779_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 589.0
TLS3_k127_3414779_10 Glutaredoxin - - - 0.0000000000000000000000000000000000000000001214 162.0
TLS3_k127_3414779_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000002779 148.0
TLS3_k127_3414779_12 DTW - - - 0.00000000000000000000000000000003096 128.0
TLS3_k127_3414779_15 extracellular matrix structural constituent - - - 0.00000000001029 73.0
TLS3_k127_3414779_16 nuclear chromosome segregation - - - 0.0000001393 64.0
TLS3_k127_3414779_2 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 418.0
TLS3_k127_3414779_3 RNA ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 366.0
TLS3_k127_3414779_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 303.0
TLS3_k127_3414779_5 RNA ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000018 291.0
TLS3_k127_3414779_7 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000003751 269.0
TLS3_k127_3414779_8 regulation of DNA repair K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000002486 237.0
TLS3_k127_3414779_9 heat shock protein binding K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000001139 252.0
TLS3_k127_3419444_0 Histidine kinase K07711,K19694 - 2.7.13.3 8.259e-200 653.0
TLS3_k127_3419444_1 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 516.0
TLS3_k127_3419444_10 - - - - 0.00000000000000000000000000000000002674 145.0
TLS3_k127_3419444_11 phosphorelay signal transduction system - - - 0.0000000000000000000006519 113.0
TLS3_k127_3419444_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 415.0
TLS3_k127_3419444_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 399.0
TLS3_k127_3419444_4 flavoprotein involved in K transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 310.0
TLS3_k127_3419444_9 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000003459 160.0
TLS3_k127_3433775_0 Glycosyl hydrolases family 25 K07273 - - 0.00000000000000000000000000000000000000000000000000000000000002165 223.0
TLS3_k127_3433775_2 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000005076 171.0
TLS3_k127_3433775_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000005779 57.0
TLS3_k127_3469902_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 1.094e-277 863.0
TLS3_k127_3469902_1 Sarcosine oxidase K00303 - 1.5.3.1 4.884e-215 674.0
TLS3_k127_3469902_2 deoxyhypusine monooxygenase activity - - - 8.465e-198 632.0
TLS3_k127_3469902_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 371.0
TLS3_k127_3469902_4 Sigma-54 interaction domain K02584 - - 0.0000000000000000000000000000000000000000000000000006733 188.0
TLS3_k127_3494865_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 352.0
TLS3_k127_3494865_1 2OG-Fe(II) oxygenase superfamily - - - 0.000000000002538 68.0
TLS3_k127_3494865_2 Domain of unknown function (DUF4343) - - - 0.0000000002149 65.0
TLS3_k127_3495150_0 Tetratricopeptide repeat - - - 0.0 1422.0
TLS3_k127_3495150_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00122 - 1.17.1.9 1.254e-290 910.0
TLS3_k127_3495150_2 Dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 390.0
TLS3_k127_3495150_3 High confidence in function and specificity K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001991 279.0
TLS3_k127_3495150_4 High confidence in function and specificity K07484 - - 0.00000000000000000000000000007393 121.0
TLS3_k127_3495150_5 ATPase (AAA superfamily - - - 0.00000000005904 68.0
TLS3_k127_3495150_6 - - - - 0.000000002202 66.0
TLS3_k127_3500706_0 Required for chromosome condensation and partitioning K03529 - - 1.318e-211 665.0
TLS3_k127_3500706_1 Alcohol dehydrogenase GroES-like domain K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 520.0
TLS3_k127_3500706_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 321.0
TLS3_k127_3500706_3 FAD binding domain - - - 0.0000000000000000001263 90.0
TLS3_k127_3514764_0 repeat protein - - - 0.0 5493.0
TLS3_k127_3514764_1 Tetratricopeptide repeat - - - 0.0 1937.0
TLS3_k127_3514764_11 Bacterial regulatory proteins, tetR family - - - 0.000000000000005308 86.0
TLS3_k127_3514764_2 FHA domain - - - 0.0 1133.0
TLS3_k127_3514764_3 Tetratricopeptide repeat - - - 3.692e-299 953.0
TLS3_k127_3514764_4 adventurous gliding protein T - - - 2.927e-204 647.0
TLS3_k127_3514764_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 457.0
TLS3_k127_3514764_6 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 370.0
TLS3_k127_3514764_8 serine threonine protein kinase - - - 0.00000000000000000000000000000000000002003 144.0
TLS3_k127_3514764_9 nuclease activity K07460 - - 0.000000000000000000000000000000000006962 143.0
TLS3_k127_3515458_0 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 2.481e-256 818.0
TLS3_k127_3515458_2 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 418.0
TLS3_k127_3515458_3 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 392.0
TLS3_k127_3515458_4 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 316.0
TLS3_k127_3515458_5 electron transfer activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 301.0
TLS3_k127_3515458_6 Transposase K07483 - - 0.0000000000000000000001421 101.0
TLS3_k127_3519469_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 321.0
TLS3_k127_3519469_1 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000001441 228.0
TLS3_k127_3519469_2 - - - - 0.00000000000000000000000000006634 124.0
TLS3_k127_3519469_3 Conserved hypothetical protein 698 - - - 0.0000000000000000000003963 112.0
TLS3_k127_3530116_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1803.0
TLS3_k127_3530116_1 PrkA AAA domain K07180 - - 0.0 1305.0
TLS3_k127_3530116_10 Glycosyl transferase, family 2 K10211 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 317.0
TLS3_k127_3530116_11 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00571,K00847,K00852 - 2.1.1.72,2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000002058 198.0
TLS3_k127_3530116_12 Asparagine synthase - - - 0.000000000000000000000000000000000000000000000000001523 205.0
TLS3_k127_3530116_13 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000007314 129.0
TLS3_k127_3530116_14 carbohydrate kinase activity - - - 0.00000000000000004427 93.0
TLS3_k127_3530116_15 PHP domain protein - - - 0.00000008391 59.0
TLS3_k127_3530116_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.427e-264 827.0
TLS3_k127_3530116_3 Belongs to the CarA family K01956 - 6.3.5.5 1.646e-200 629.0
TLS3_k127_3530116_4 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 582.0
TLS3_k127_3530116_5 Rhs family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 429.0
TLS3_k127_3530116_6 Peptidase M15 K02395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 393.0
TLS3_k127_3530116_7 UDP-glucoronosyl and UDP-glucosyl transferase K14596 - 2.4.1.276 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 379.0
TLS3_k127_3530116_8 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 373.0
TLS3_k127_3530116_9 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 354.0
TLS3_k127_3536199_0 A-macroglobulin complement component - - - 2.222e-239 793.0
TLS3_k127_3536199_1 dipeptidyl-peptidase activity K06978 - - 5.758e-228 731.0
TLS3_k127_3536199_10 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000002187 169.0
TLS3_k127_3536199_11 Anti-sigma regulatory factor (Ser Thr protein kinase) K17752 - 2.7.11.1 0.00000000000000000000000000000008009 141.0
TLS3_k127_3536199_12 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000694 139.0
TLS3_k127_3536199_13 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000002617 138.0
TLS3_k127_3536199_14 antisigma factor binding K17762 - - 0.000000000000000000000003729 106.0
TLS3_k127_3536199_15 lactoylglutathione lyase activity - - - 0.00000000000000000000344 101.0
TLS3_k127_3536199_16 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000007952 92.0
TLS3_k127_3536199_2 RmlD substrate binding domain K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 489.0
TLS3_k127_3536199_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 423.0
TLS3_k127_3536199_4 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 398.0
TLS3_k127_3536199_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 378.0
TLS3_k127_3536199_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000018 274.0
TLS3_k127_3536199_7 STAS domain K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000001773 244.0
TLS3_k127_3536199_8 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000000000000238 213.0
TLS3_k127_3539913_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1537.0
TLS3_k127_3539913_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 449.0
TLS3_k127_3539913_2 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 409.0
TLS3_k127_3539913_3 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 343.0
TLS3_k127_3539913_4 regulation of translation K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000009522 114.0
TLS3_k127_3539913_5 Uncharacterised protein family (UPF0158) - - - 0.00000000000000000000000003646 117.0
TLS3_k127_3544993_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1700.0
TLS3_k127_3544993_1 Belongs to the aldehyde dehydrogenase family K00138 - - 9.24e-282 872.0
TLS3_k127_3544993_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 411.0
TLS3_k127_3544993_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 325.0
TLS3_k127_3544993_4 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000002355 241.0
TLS3_k127_3544993_5 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000003811 234.0
TLS3_k127_3544993_6 STAS domain K17763 - - 0.00000000000000000000000000000000000000000000000001108 196.0
TLS3_k127_3544993_7 Protein of unknown function (DUF779) K09959 - - 0.00000000000000000000000000000000000000000000006366 181.0
TLS3_k127_3556980_0 Uncharacterized protein conserved in bacteria (DUF2169) - - - 7.245e-195 636.0
TLS3_k127_3556980_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 374.0
TLS3_k127_3556980_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 293.0
TLS3_k127_3556980_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 292.0
TLS3_k127_3556980_4 Chemotaxis protein CheY K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009458 245.0
TLS3_k127_3565633_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 7.918e-258 799.0
TLS3_k127_3565633_1 Bacterial regulatory protein, Fis family - - - 1.316e-229 718.0
TLS3_k127_3565633_10 Transcriptional regulator, TetR family - - - 0.00002368 54.0
TLS3_k127_3565633_11 protein kinase activity - - - 0.00002615 54.0
TLS3_k127_3565633_2 4-HFC-P synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 433.0
TLS3_k127_3565633_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 386.0
TLS3_k127_3565633_4 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 289.0
TLS3_k127_3565633_5 Family membership K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003069 283.0
TLS3_k127_3565633_6 Putative esterase K07017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001541 282.0
TLS3_k127_3565633_7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000003914 144.0
TLS3_k127_3565633_9 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00001063 51.0
TLS3_k127_3573275_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 549.0
TLS3_k127_3573275_1 UPF0365 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 497.0
TLS3_k127_3573275_10 DNA-binding regulatory protein K03088 - - 0.000000000000000000000000000000000000000000003461 175.0
TLS3_k127_3573275_11 Domain of unknown function (DUF2383) - - - 0.00000000000000000000000000000000000000000001071 169.0
TLS3_k127_3573275_12 - - - - 0.00000000000000000000000000001679 124.0
TLS3_k127_3573275_13 PAS fold - - - 0.0000000000000002466 84.0
TLS3_k127_3573275_16 permease - - - 0.0004353 51.0
TLS3_k127_3573275_2 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 502.0
TLS3_k127_3573275_3 Histidine kinase K10909 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 474.0
TLS3_k127_3573275_4 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 460.0
TLS3_k127_3573275_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 389.0
TLS3_k127_3573275_6 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 341.0
TLS3_k127_3573275_7 peptide catabolic process K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 338.0
TLS3_k127_3573275_8 DinB family - - - 0.00000000000000000000000000000000000000000000000000006291 191.0
TLS3_k127_3573275_9 DoxX - - - 0.00000000000000000000000000000000000000000000001715 188.0
TLS3_k127_3573462_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002149 260.0
TLS3_k127_3573462_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000001195 173.0
TLS3_k127_3573462_3 Universal stress protein - - - 0.0000000000000000003385 94.0
TLS3_k127_3573462_4 AAA ATPase domain - - - 0.00000000000001764 78.0
TLS3_k127_3596240_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0 1166.0
TLS3_k127_3596240_1 4Fe-4S single cluster domain - - - 2.36e-254 797.0
TLS3_k127_360421_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 505.0
TLS3_k127_360421_1 N-terminal domain of unknown function (DUF4140) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 410.0
TLS3_k127_360421_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 328.0
TLS3_k127_360421_3 Flotillin K07192 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000001786 247.0
TLS3_k127_360421_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000002153 206.0
TLS3_k127_360421_6 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000582 91.0
TLS3_k127_360421_7 cellular response to DNA damage stimulus - GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.00000000000003619 83.0
TLS3_k127_3604430_0 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 484.0
TLS3_k127_3604430_1 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 447.0
TLS3_k127_3604430_2 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000004501 225.0
TLS3_k127_3604430_3 Family membership - - - 0.0000000000000000000000000000000000000000000000000000006364 218.0
TLS3_k127_3604430_4 - - - - 0.000000003314 64.0
TLS3_k127_3610110_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1500.0
TLS3_k127_3610110_1 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 516.0
TLS3_k127_3610110_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000003922 220.0
TLS3_k127_3610110_3 cheY-homologous receiver domain - - - 0.000000000000000000000008699 106.0
TLS3_k127_3619831_0 MMPL family K07003 - - 0.0 1165.0
TLS3_k127_3619831_1 ABC transporter, ATP-binding protein - - - 2.86e-308 960.0
TLS3_k127_3619831_11 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000003011 173.0
TLS3_k127_3619831_12 cheY-homologous receiver domain - - - 0.000000000000000000000001423 108.0
TLS3_k127_3619831_2 fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 487.0
TLS3_k127_3619831_3 unsaturated fatty acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 476.0
TLS3_k127_3619831_4 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 391.0
TLS3_k127_3619831_5 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 300.0
TLS3_k127_3619831_6 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002588 229.0
TLS3_k127_3619831_7 PFAM DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000009517 239.0
TLS3_k127_3619831_8 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000009576 225.0
TLS3_k127_3619948_0 Amino acid adenylation domain protein - - - 0.0 1128.0
TLS3_k127_3619948_1 Pfam:HxxPF_rpt - - - 2.071e-241 765.0
TLS3_k127_3619948_2 Condensation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 598.0
TLS3_k127_3621549_0 Type II and III secretion system protein K02453 - - 0.0 1041.0
TLS3_k127_3621549_1 Polysaccharide biosynthesis protein - - - 2.433e-262 824.0
TLS3_k127_3621549_10 Type II secretion system (T2SS), protein J K02459 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 299.0
TLS3_k127_3621549_11 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003699 280.0
TLS3_k127_3621549_12 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001097 252.0
TLS3_k127_3621549_13 Prokaryotic N-terminal methylation motif K02458 - - 0.000000000000000000000000000000000000000000000000000000000002499 218.0
TLS3_k127_3621549_14 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000001252 194.0
TLS3_k127_3621549_16 GAF domain - - - 0.0000000000000000000000000000000000000000000000009907 193.0
TLS3_k127_3621549_17 general secretion pathway protein K02456 - - 0.000000000000000000000000000000000000000000001396 168.0
TLS3_k127_3621549_18 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000001134 158.0
TLS3_k127_3621549_2 response regulator K07713 - - 7.739e-255 790.0
TLS3_k127_3621549_20 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000001859 112.0
TLS3_k127_3621549_3 General secretion pathway protein F K02455,K02653 - - 2.84e-200 629.0
TLS3_k127_3621549_4 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 586.0
TLS3_k127_3621549_5 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 484.0
TLS3_k127_3621549_6 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 427.0
TLS3_k127_3621549_7 General secretion pathway protein C K02452 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 395.0
TLS3_k127_3621549_8 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 342.0
TLS3_k127_3621549_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 308.0
TLS3_k127_3628608_0 oligosaccharyl transferase activity - - - 6.052e-307 958.0
TLS3_k127_3628608_1 His Kinase A (phosphoacceptor) domain - - - 2.207e-244 766.0
TLS3_k127_3628608_2 Gaf domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000415 286.0
TLS3_k127_3628608_3 Diacylglycerol acyltransferase - - - 0.000000000000000000000000000000000000000000000000005055 192.0
TLS3_k127_3628608_4 - - - - 0.00000000000000000000000000000000329 135.0
TLS3_k127_3628608_5 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000337 118.0
TLS3_k127_3648210_0 AMP-binding enzyme - - - 2.684e-309 960.0
TLS3_k127_3648210_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.695e-244 775.0
TLS3_k127_3648210_10 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 383.0
TLS3_k127_3648210_11 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 358.0
TLS3_k127_3648210_12 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 316.0
TLS3_k127_3648210_13 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 294.0
TLS3_k127_3648210_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001747 265.0
TLS3_k127_3648210_15 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000005446 261.0
TLS3_k127_3648210_16 protein tyrosine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001393 263.0
TLS3_k127_3648210_17 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003205 247.0
TLS3_k127_3648210_18 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000001737 201.0
TLS3_k127_3648210_19 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.000000000000000000000000000000000000000000000000000001426 201.0
TLS3_k127_3648210_2 phosphoserine phosphatase activity K01768,K07315,K16922 - 3.1.3.3,4.6.1.1 1.526e-231 731.0
TLS3_k127_3648210_21 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000000000001284 154.0
TLS3_k127_3648210_22 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000000000000001255 146.0
TLS3_k127_3648210_23 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000007991 118.0
TLS3_k127_3648210_24 Putative zinc- or iron-chelating domain - - - 0.000000000000000000008788 106.0
TLS3_k127_3648210_25 Acyltransferase - - - 0.0000000000000003252 89.0
TLS3_k127_3648210_26 pyrroloquinoline quinone binding - - - 0.00000000001495 77.0
TLS3_k127_3648210_27 - - - - 0.000002119 60.0
TLS3_k127_3648210_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 7.316e-220 689.0
TLS3_k127_3648210_4 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 7.377e-204 655.0
TLS3_k127_3648210_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 546.0
TLS3_k127_3648210_6 Pectate lyase K01728,K21606 - 3.2.1.202,4.2.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 475.0
TLS3_k127_3648210_7 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 417.0
TLS3_k127_3648210_8 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 410.0
TLS3_k127_3648210_9 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 396.0
TLS3_k127_3650467_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1427.0
TLS3_k127_3650467_1 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 8.225e-200 630.0
TLS3_k127_3650467_3 PFAM Formylglycine-generating sulfatase enzyme K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 337.0
TLS3_k127_3650467_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001569 280.0
TLS3_k127_3650467_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000007325 223.0
TLS3_k127_3650467_6 - - - - 0.00000000000000000000000000000000000000000000000000000000009871 214.0
TLS3_k127_3650467_7 Cytochrome C biogenesis protein K02200 - - 0.00000000000000000000000000000000000000005306 156.0
TLS3_k127_3665203_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 498.0
TLS3_k127_3665203_1 PFAM Mo-dependent nitrogenase - - - 0.0000000000000000000000000000000000456 138.0
TLS3_k127_3665203_2 solute binding protein K02035 - - 0.0000000000358 75.0
TLS3_k127_3665434_0 peptidyl-tyrosine sulfation - - - 3.573e-262 843.0
TLS3_k127_3665434_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 5.718e-230 726.0
TLS3_k127_3665434_11 PFAM NUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.000000000000000000000000000007535 129.0
TLS3_k127_3665434_2 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 586.0
TLS3_k127_3665434_3 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 566.0
TLS3_k127_3665434_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 549.0
TLS3_k127_3665434_5 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 467.0
TLS3_k127_3665434_6 histone H2A K63-linked ubiquitination K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 399.0
TLS3_k127_3665434_7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 354.0
TLS3_k127_3665434_8 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 321.0
TLS3_k127_3665434_9 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002027 258.0
TLS3_k127_3667426_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 545.0
TLS3_k127_3667426_2 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 333.0
TLS3_k127_3667426_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000002513 203.0
TLS3_k127_3675099_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0 1059.0
TLS3_k127_3675099_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 591.0
TLS3_k127_3675099_2 Threonine/Serine exporter, ThrE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 461.0
TLS3_k127_3675099_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 442.0
TLS3_k127_3675099_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 416.0
TLS3_k127_3675099_5 protein homooligomerization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 356.0
TLS3_k127_3675099_6 general secretion pathway protein K02456,K02458 - - 0.0000000000000000000000000000000000000000008463 168.0
TLS3_k127_3675099_7 DUF218 domain - - - 0.0000000000000000000000000000000001769 140.0
TLS3_k127_3675099_8 regulation of fungal-type cell wall biogenesis - - - 0.0002556 53.0
TLS3_k127_368271_0 Peptidase family M1 domain K01256 - 3.4.11.2 0.0 1194.0
TLS3_k127_368271_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 416.0
TLS3_k127_368271_10 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 307.0
TLS3_k127_368271_11 short chain dehydrogenase reductase family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 296.0
TLS3_k127_368271_12 Extensin-like protein C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 291.0
TLS3_k127_368271_13 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000000000008467 236.0
TLS3_k127_368271_15 AAA domain - - - 0.00000000000000000000000000000000000000000000001974 185.0
TLS3_k127_368271_17 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000001405 166.0
TLS3_k127_368271_18 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000009558 133.0
TLS3_k127_368271_19 carboxylic ester hydrolase activity - - - 0.00005803 55.0
TLS3_k127_368271_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 363.0
TLS3_k127_368271_3 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 367.0
TLS3_k127_368271_4 Phosphoribulokinase / Uridine kinase family K00855,K00876 - 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 336.0
TLS3_k127_368271_5 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 334.0
TLS3_k127_368271_6 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 347.0
TLS3_k127_368271_7 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 351.0
TLS3_k127_368271_8 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 329.0
TLS3_k127_368271_9 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 325.0
TLS3_k127_3691486_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 465.0
TLS3_k127_3691486_10 - - - - 0.00000001116 67.0
TLS3_k127_3691486_11 - - - - 0.00001498 54.0
TLS3_k127_3691486_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 400.0
TLS3_k127_3691486_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 394.0
TLS3_k127_3691486_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 340.0
TLS3_k127_3691486_5 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 341.0
TLS3_k127_3691486_6 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 329.0
TLS3_k127_3691486_7 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000001714 221.0
TLS3_k127_3711338_0 SMART serine threonine protein kinase - - - 3.871e-219 723.0
TLS3_k127_3711338_1 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 541.0
TLS3_k127_3711338_2 anaphase-promoting complex binding - - - 0.0000000001311 63.0
TLS3_k127_3719611_0 COG0515 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 468.0
TLS3_k127_3719611_1 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 340.0
TLS3_k127_3719611_3 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000003479 210.0
TLS3_k127_3730312_0 peptidase S8 - - - 2.39e-246 788.0
TLS3_k127_3730312_1 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 1.539e-234 737.0
TLS3_k127_3730312_2 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 585.0
TLS3_k127_3730312_3 Pectate lyase K01728,K21606 - 3.2.1.202,4.2.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 533.0
TLS3_k127_3730312_4 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 493.0
TLS3_k127_3730312_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 341.0
TLS3_k127_3730312_6 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000003819 195.0
TLS3_k127_3730312_7 DUF218 domain - - - 0.00000000000000000000000000000000000000006044 161.0
TLS3_k127_3730312_8 - - - - 0.0000000000000000000000000000000000006269 153.0
TLS3_k127_3730312_9 protein kinase activity - - - 0.00000000001347 78.0
TLS3_k127_3732823_0 Rhs family - - - 0.0 1142.0
TLS3_k127_3732823_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5e-324 998.0
TLS3_k127_3732823_10 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 385.0
TLS3_k127_3732823_11 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 374.0
TLS3_k127_3732823_12 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 363.0
TLS3_k127_3732823_13 Asp/Glu/Hydantoin racemase K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 349.0
TLS3_k127_3732823_14 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 344.0
TLS3_k127_3732823_15 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 344.0
TLS3_k127_3732823_16 2OG-Fe dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 324.0
TLS3_k127_3732823_17 3D domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 308.0
TLS3_k127_3732823_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 305.0
TLS3_k127_3732823_19 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 293.0
TLS3_k127_3732823_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.106e-264 829.0
TLS3_k127_3732823_20 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 295.0
TLS3_k127_3732823_21 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 291.0
TLS3_k127_3732823_25 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005845 270.0
TLS3_k127_3732823_26 Histidine kinase-like ATPases K17752 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001273 257.0
TLS3_k127_3732823_27 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002254 250.0
TLS3_k127_3732823_28 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000006518 213.0
TLS3_k127_3732823_29 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17762 - - 0.00000000000000000000000000000000000000000000000000000005224 201.0
TLS3_k127_3732823_3 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 4.05e-253 788.0
TLS3_k127_3732823_30 Sigma factor PP2C-like phosphatases K05518 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000005344 197.0
TLS3_k127_3732823_31 Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000000000001719 183.0
TLS3_k127_3732823_32 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001137 175.0
TLS3_k127_3732823_33 Adenylylsulfate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000001825 176.0
TLS3_k127_3732823_34 STAS domain K17763 - - 0.0000000000000000000000000000000000000000000002588 175.0
TLS3_k127_3732823_36 Competence protein J (ComJ) - - - 0.00000000000000000000005368 106.0
TLS3_k127_3732823_38 peptidyl-tyrosine sulfation - - - 0.000000000000004781 82.0
TLS3_k127_3732823_4 IgGFc binding protein - - - 1.061e-212 677.0
TLS3_k127_3732823_41 serine threonine protein kinase K17752 - 2.7.11.1 0.00000000001275 70.0
TLS3_k127_3732823_5 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 595.0
TLS3_k127_3732823_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 574.0
TLS3_k127_3732823_7 PFAM VanW family protein K18346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 524.0
TLS3_k127_3732823_9 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 408.0
TLS3_k127_3750539_0 Rhs family - - - 0.0 1292.0
TLS3_k127_3750539_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 5.396e-251 778.0
TLS3_k127_3750539_10 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002744 243.0
TLS3_k127_3750539_11 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000002249 187.0
TLS3_k127_3750539_12 Lipoprotein amino terminal region - - - 0.00000000000000000005319 106.0
TLS3_k127_3750539_13 domain, Protein - - - 0.000000000000000003608 102.0
TLS3_k127_3750539_14 - - - - 0.000000000002282 79.0
TLS3_k127_3750539_15 - - - - 0.000000001106 62.0
TLS3_k127_3750539_17 amine dehydrogenase activity - - - 0.000001274 61.0
TLS3_k127_3750539_2 Pfam:Kce K18013 - 2.3.1.247 1.422e-224 704.0
TLS3_k127_3750539_3 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 540.0
TLS3_k127_3750539_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 383.0
TLS3_k127_3750539_5 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 375.0
TLS3_k127_3750539_6 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 372.0
TLS3_k127_3750539_7 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 388.0
TLS3_k127_3750539_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 372.0
TLS3_k127_3750539_9 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 334.0
TLS3_k127_3766707_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1915.0
TLS3_k127_3766707_1 SMART serine threonine protein kinase - - - 0.0 1189.0
TLS3_k127_3766707_10 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000008472 114.0
TLS3_k127_3766707_11 Sigma-54 interaction domain K02481,K07714 - - 0.0000000000000000000001331 99.0
TLS3_k127_3766707_13 protein serine/threonine phosphatase activity K20074 - 3.1.3.16 0.00000001439 64.0
TLS3_k127_3766707_14 histone H2A K63-linked ubiquitination - - - 0.00000002196 64.0
TLS3_k127_3766707_2 Protein kinase domain K12132 - 2.7.11.1 1.508e-310 1004.0
TLS3_k127_3766707_3 UvrD-like helicase C-terminal domain - - - 4.088e-270 852.0
TLS3_k127_3766707_4 Aminotransferase class I and II - - - 3.801e-257 818.0
TLS3_k127_3766707_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 492.0
TLS3_k127_3766707_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 445.0
TLS3_k127_3766707_7 Glycosyl hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 421.0
TLS3_k127_3766707_8 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 355.0
TLS3_k127_376947_0 response regulator K07714 - - 2.037e-227 718.0
TLS3_k127_376947_10 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 345.0
TLS3_k127_376947_11 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 331.0
TLS3_k127_376947_12 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 291.0
TLS3_k127_376947_13 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002097 280.0
TLS3_k127_376947_14 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001095 264.0
TLS3_k127_376947_15 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000001297 231.0
TLS3_k127_376947_17 Belongs to the MIP aquaporin (TC 1.A.8) family K02440,K06188 - - 0.0000000000000000000000000000000000000000000000000005882 193.0
TLS3_k127_376947_18 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.000000000000000000000000000000001955 147.0
TLS3_k127_376947_2 Cys Met metabolism K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 584.0
TLS3_k127_376947_21 - - - - 0.00000000000000000000000000004767 133.0
TLS3_k127_376947_23 Forkhead associated domain - - - 0.00000000000000000000000004594 124.0
TLS3_k127_376947_24 Putative metal-binding motif - - - 0.000000000000000000000002898 119.0
TLS3_k127_376947_26 Flavin reductase like domain - - - 0.000000000000000749 84.0
TLS3_k127_376947_3 enoyl-[acyl-carrier-protein] reductase (NADH) activity K00209 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.44,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 543.0
TLS3_k127_376947_4 Polysaccharide biosynthesis protein K03328 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 486.0
TLS3_k127_376947_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 486.0
TLS3_k127_376947_6 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 444.0
TLS3_k127_376947_7 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 415.0
TLS3_k127_376947_8 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 393.0
TLS3_k127_376947_9 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 376.0
TLS3_k127_3777867_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1237.0
TLS3_k127_3777867_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.487e-244 764.0
TLS3_k127_3777867_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 460.0
TLS3_k127_3777867_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 350.0
TLS3_k127_3777867_4 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000000000001103 241.0
TLS3_k127_3795435_0 antisigma factor binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 415.0
TLS3_k127_3795435_1 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 397.0
TLS3_k127_3795435_2 peptidase family M13 K07386 - - 0.0000000000000000000000000000000000000000000000000000001005 199.0
TLS3_k127_382525_0 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 459.0
TLS3_k127_382525_1 Family membership K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 448.0
TLS3_k127_382525_2 Binding-protein-dependent transport system inner membrane component K02050,K15599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 351.0
TLS3_k127_382525_3 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 341.0
TLS3_k127_382525_4 cell envelope organization K05807,K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000002324 239.0
TLS3_k127_382525_5 protein domain associated with - - - 0.00000000000000000000000000000000000003407 158.0
TLS3_k127_382525_6 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000007615 65.0
TLS3_k127_3836154_0 Domain of unknown function (DUF4175) - - - 7.992e-319 1003.0
TLS3_k127_3836154_1 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 7.285e-236 743.0
TLS3_k127_3836154_10 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 302.0
TLS3_k127_3836154_11 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003985 291.0
TLS3_k127_3836154_12 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009589 276.0
TLS3_k127_3836154_13 histone H2A K63-linked ubiquitination K03220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001999 271.0
TLS3_k127_3836154_14 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000001056 209.0
TLS3_k127_3836154_15 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000002286 183.0
TLS3_k127_3836154_16 - - - - 0.0000000000000000000000000000000000000000000000107 197.0
TLS3_k127_3836154_17 protein conserved in bacteria K11904 - - 0.000000000000000000000000000000000009087 149.0
TLS3_k127_3836154_18 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000001452 131.0
TLS3_k127_3836154_19 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000000000000000000000000001599 136.0
TLS3_k127_3836154_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 6.758e-231 725.0
TLS3_k127_3836154_21 Glycosyl hydrolases family 25 K01185,K07273 - 3.2.1.17 0.000000000002148 80.0
TLS3_k127_3836154_22 23S rRNA-intervening sequence protein - - - 0.000000000005024 77.0
TLS3_k127_3836154_23 cell adhesion involved in biofilm formation - - - 0.0000000004794 68.0
TLS3_k127_3836154_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 646.0
TLS3_k127_3836154_4 DnaJ C terminal domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 425.0
TLS3_k127_3836154_5 ABC transporter permease K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 410.0
TLS3_k127_3836154_6 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 400.0
TLS3_k127_3836154_7 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 402.0
TLS3_k127_3836154_8 Rhomboid family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 313.0
TLS3_k127_3836154_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 316.0
TLS3_k127_3840231_0 NUBPL iron-transfer P-loop NTPase K04562 - - 7.277e-225 718.0
TLS3_k127_3840231_1 Protein of unknown function (DUF1015) - - - 4.666e-220 687.0
TLS3_k127_3840231_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 534.0
TLS3_k127_3840231_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001251 241.0
TLS3_k127_3840231_4 cell envelope organization K05807,K08309 - - 0.000000000000000000000000000000000000000000000003182 186.0
TLS3_k127_3851765_0 Bacterial regulatory protein, Fis family K02584 - - 0.0 1492.0
TLS3_k127_3851765_1 SNF2 family N-terminal domain - - - 9.476e-298 937.0
TLS3_k127_3851765_10 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000001628 226.0
TLS3_k127_3851765_11 Protein of unknown function (DUF3105) - - - 0.000000000000000000000000000000000000000000000000002893 194.0
TLS3_k127_3851765_13 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000002216 142.0
TLS3_k127_3851765_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.378e-256 801.0
TLS3_k127_3851765_3 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 609.0
TLS3_k127_3851765_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 419.0
TLS3_k127_3851765_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 349.0
TLS3_k127_3851765_6 Cytochrome c oxidase subunit K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003611 283.0
TLS3_k127_3851765_7 protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001466 269.0
TLS3_k127_3851765_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004643 259.0
TLS3_k127_3851765_9 Cytochrome c oxidase, subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000004049 212.0
TLS3_k127_3868432_0 Type II IV secretion system protein K02283,K03609 - - 1.072e-221 711.0
TLS3_k127_3868432_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 429.0
TLS3_k127_3868432_2 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 345.0
TLS3_k127_3868432_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001287 268.0
TLS3_k127_3868432_4 Cold shock protein K03704 - - 0.00000000000000000000000000000001794 136.0
TLS3_k127_3871058_0 ImcF-related N-terminal domain K11891 - - 4.539e-271 889.0
TLS3_k127_3871058_1 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 4.444e-244 762.0
TLS3_k127_3871058_10 Gene 25-like lysozyme K11897 - - 0.00000000000000000000000000000000002734 140.0
TLS3_k127_3871058_2 Type VI secretion system, TssF K11896 - - 5.032e-231 734.0
TLS3_k127_3871058_3 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 357.0
TLS3_k127_3871058_4 Type VI secretion, TssG K11895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 330.0
TLS3_k127_3871058_5 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 288.0
TLS3_k127_3871058_6 ImpA, N-terminal, type VI secretion system K11902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 317.0
TLS3_k127_3871058_7 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000004919 201.0
TLS3_k127_3871058_8 - K11918 - - 0.000000000000000000000000000000000000000000006958 171.0
TLS3_k127_3871058_9 Type VI secretion system protein DotU K11892 - - 0.000000000000000000000000000000000000000134 172.0
TLS3_k127_3878987_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 7.355e-300 927.0
TLS3_k127_3878987_1 Zn-dependent proteases and their inactivated homologs K03592 - - 1.169e-234 741.0
TLS3_k127_3878987_2 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 4.674e-203 661.0
TLS3_k127_3878987_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 426.0
TLS3_k127_3878987_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 296.0
TLS3_k127_3878987_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 314.0
TLS3_k127_3878987_6 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K01647,K22491 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006346 256.0
TLS3_k127_3878987_7 chlorophyll binding K21218 - - 0.000000000000000000000000000000000000000000000191 173.0
TLS3_k127_3878987_8 sequence-specific DNA binding K07726 - - 0.00000000000000000000000000000000000000001983 156.0
TLS3_k127_3878987_9 Metalloprotease - - - 0.0000000000001393 70.0
TLS3_k127_390643_0 HD domain - - - 1.948e-269 846.0
TLS3_k127_390643_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 471.0
TLS3_k127_3907237_0 non-ribosomal peptide synthetase - - - 0.0 1078.0
TLS3_k127_3907237_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000001587 86.0
TLS3_k127_3943255_0 Amino acid adenylation domain protein - - - 0.0 1385.0
TLS3_k127_3955937_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1448.0
TLS3_k127_3955937_1 ABC-type oligopeptide transport system periplasmic component K02035,K12368,K13893,K15580,K16199,K19226 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 3.714e-285 895.0
TLS3_k127_3955937_10 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 503.0
TLS3_k127_3955937_11 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 503.0
TLS3_k127_3955937_12 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 466.0
TLS3_k127_3955937_13 peptidoglycan binding K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 468.0
TLS3_k127_3955937_14 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 462.0
TLS3_k127_3955937_15 NUBPL iron-transfer P-loop NTPase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 429.0
TLS3_k127_3955937_16 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 415.0
TLS3_k127_3955937_17 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 405.0
TLS3_k127_3955937_18 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 353.0
TLS3_k127_3955937_19 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 344.0
TLS3_k127_3955937_2 Multicopper oxidase - - - 1.089e-284 887.0
TLS3_k127_3955937_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 314.0
TLS3_k127_3955937_21 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 254.0
TLS3_k127_3955937_22 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000143 251.0
TLS3_k127_3955937_25 lipoprotein transporter activity K02003,K09814 - - 0.0000000000000000000000000000000000000000000000000000000000002361 232.0
TLS3_k127_3955937_27 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000009233 207.0
TLS3_k127_3955937_28 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000006959 183.0
TLS3_k127_3955937_29 transcriptional regulator - - - 0.0000000000000000000000000000000000000001954 157.0
TLS3_k127_3955937_3 Selenium-binding protein K17285 - - 5.301e-274 846.0
TLS3_k127_3955937_31 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000000000000000000000000000000134 140.0
TLS3_k127_3955937_32 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000002022 130.0
TLS3_k127_3955937_33 STAS domain K17763 - - 0.0000000000000000000000001443 123.0
TLS3_k127_3955937_34 phosphate-selective porin O and P - - - 0.000000000000000000000009779 114.0
TLS3_k127_3955937_35 - - - - 0.0000000000000000000001102 105.0
TLS3_k127_3955937_36 Protein of unknown function (DUF2892) - - - 0.000000000000000000000116 100.0
TLS3_k127_3955937_37 - - - - 0.0000000000000000000008739 104.0
TLS3_k127_3955937_39 UDP-glucoronosyl and UDP-glucosyl transferase K16388 - - 0.00000000000000000129 93.0
TLS3_k127_3955937_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 9.3e-261 805.0
TLS3_k127_3955937_41 transferase activity, transferring hexosyl groups K00699 - 2.4.1.17 0.00000000611 67.0
TLS3_k127_3955937_42 PPIC-type PPIASE domain - - - 0.000000008282 57.0
TLS3_k127_3955937_5 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.652e-243 762.0
TLS3_k127_3955937_6 Protein of unknown function (DUF1573) - - - 6.938e-194 625.0
TLS3_k127_3955937_7 Pfam Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 612.0
TLS3_k127_3955937_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 597.0
TLS3_k127_3955937_9 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 523.0
TLS3_k127_395933_0 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 456.0
TLS3_k127_395933_1 Thiol oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 430.0
TLS3_k127_395933_10 Glutaredoxin K05309 - 5.3.99.3 0.000000000000000000000000000002242 129.0
TLS3_k127_395933_2 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 339.0
TLS3_k127_395933_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000003309 256.0
TLS3_k127_395933_5 Putative exonuclease, RdgC K03554 - - 0.000000000000000000000000000000000000000000000000007414 191.0
TLS3_k127_395933_6 proteins of the AP superfamily - - - 0.00000000000000000000000000000000000000000000000003385 203.0
TLS3_k127_395933_7 May be involved in recombination - - - 0.00000000000000000000000000000000000000000001448 176.0
TLS3_k127_395933_8 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000000000000000000004905 157.0
TLS3_k127_3969461_0 Fungalysin metallopeptidase (M36) - - - 0.0 1121.0
TLS3_k127_3969461_1 protein kinase activity - - - 3.364e-290 919.0
TLS3_k127_3969461_2 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 569.0
TLS3_k127_3969461_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 537.0
TLS3_k127_3969461_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 476.0
TLS3_k127_3969461_5 Uncharacterized conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 370.0
TLS3_k127_3969461_6 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000005899 173.0
TLS3_k127_3969461_8 shikimate kinase activity K04093 - 5.4.99.5 0.000000000000000000000000000000000000005551 169.0
TLS3_k127_4015074_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 1.314e-260 835.0
TLS3_k127_4015074_1 ABC transporter - - - 3.451e-197 627.0
TLS3_k127_4015074_2 phosphatase homologous to the C-terminal domain of histone macroH2A1 - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 604.0
TLS3_k127_4015074_3 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 571.0
TLS3_k127_4015074_4 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000003588 174.0
TLS3_k127_4015074_5 PIN domain K18828 - - 0.000000000000000000000000265 116.0
TLS3_k127_4015074_6 Heat shock protein DnaJ domain protein - - - 0.000000000000004068 77.0
TLS3_k127_4015074_7 - K18829 - - 0.00000000002068 67.0
TLS3_k127_4015074_8 - - - - 0.0005045 47.0
TLS3_k127_403650_0 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 483.0
TLS3_k127_403650_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 458.0
TLS3_k127_403650_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 400.0
TLS3_k127_403650_3 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001445 248.0
TLS3_k127_403650_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000001309 216.0
TLS3_k127_403650_5 - - - - 0.000000002355 63.0
TLS3_k127_405920_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.479e-248 775.0
TLS3_k127_405920_1 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 563.0
TLS3_k127_405920_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 529.0
TLS3_k127_405920_3 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 511.0
TLS3_k127_405920_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 355.0
TLS3_k127_405920_5 - - - - 0.000000000003659 72.0
TLS3_k127_4061004_0 SCP-2 sterol transfer family - - - 0.0 1125.0
TLS3_k127_4061004_1 Belongs to the thiolase family K00626 - 2.3.1.9 2.183e-216 679.0
TLS3_k127_4061004_10 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000009758 155.0
TLS3_k127_4061004_11 COG1002 Type II restriction enzyme, methylase subunits - - - 0.00000000000000000000000000000000000002714 151.0
TLS3_k127_4061004_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000001912 136.0
TLS3_k127_4061004_13 Belongs to the peptidase S8 family K01179 - 3.2.1.4 0.000000000000000000000005424 120.0
TLS3_k127_4061004_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 1.06e-208 689.0
TLS3_k127_4061004_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 474.0
TLS3_k127_4061004_4 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 430.0
TLS3_k127_4061004_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 426.0
TLS3_k127_4061004_6 Pas domain K02660,K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001362 276.0
TLS3_k127_4061004_7 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000003286 254.0
TLS3_k127_4061004_8 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000009339 213.0
TLS3_k127_40979_0 ABC transporter - - - 1.575e-305 952.0
TLS3_k127_40979_1 Lantibiotic dehydratase, C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 503.0
TLS3_k127_40979_10 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000001859 142.0
TLS3_k127_40979_11 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000001509 108.0
TLS3_k127_40979_12 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.0000000000000000000002317 112.0
TLS3_k127_40979_2 CBD_II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 488.0
TLS3_k127_40979_3 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 435.0
TLS3_k127_40979_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 421.0
TLS3_k127_40979_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 413.0
TLS3_k127_40979_6 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 400.0
TLS3_k127_40979_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000008987 228.0
TLS3_k127_4098838_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1077.0
TLS3_k127_4098838_1 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 - 3.2.1.141 5.426e-225 715.0
TLS3_k127_4098838_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.247e-202 644.0
TLS3_k127_4098838_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 385.0
TLS3_k127_4098838_4 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000001072 123.0
TLS3_k127_4098838_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000002513 129.0
TLS3_k127_4134033_0 PFAM major facilitator superfamily MFS_1 - - - 9.749e-269 834.0
TLS3_k127_4134033_1 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 486.0
TLS3_k127_4134033_2 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004737 290.0
TLS3_k127_4134033_3 Membrane - - - 0.00000000000000000000000000000000000000000000003067 175.0
TLS3_k127_4136246_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 447.0
TLS3_k127_4136246_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 385.0
TLS3_k127_4136246_2 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
TLS3_k127_4136246_4 oxidoreductase activity - - - 0.00000000000000000002272 101.0
TLS3_k127_4214568_0 type III restriction protein res subunit K01153 - 3.1.21.3 0.0 1266.0
TLS3_k127_4214568_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 494.0
TLS3_k127_4214568_11 Anti-sigma regulatory factor (Ser Thr protein kinase) K17752 - 2.7.11.1 0.0000000000000000000000001489 115.0
TLS3_k127_4214568_12 NUDIX domain - - - 0.00000000000000000000004081 107.0
TLS3_k127_4214568_13 cell envelope organization K05807,K08309 - - 0.000000000000000003077 98.0
TLS3_k127_4214568_15 PLD-like domain - - - 0.00000003371 59.0
TLS3_k127_4214568_16 Belongs to the peptidase S8 family - - - 0.0000004324 62.0
TLS3_k127_4214568_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 423.0
TLS3_k127_4214568_3 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 364.0
TLS3_k127_4214568_4 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 365.0
TLS3_k127_4214568_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 355.0
TLS3_k127_4214568_6 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000003578 266.0
TLS3_k127_4214568_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007429 272.0
TLS3_k127_4214568_8 STAS domain K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000489 246.0
TLS3_k127_4214568_9 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000004078 225.0
TLS3_k127_4240882_0 4Fe-4S dicluster domain - - - 0.0 1250.0
TLS3_k127_4240882_1 Surface antigen K07277,K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 615.0
TLS3_k127_4240882_3 PAS domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 344.0
TLS3_k127_4240882_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000009898 177.0
TLS3_k127_4240882_7 cheY-homologous receiver domain - - - 0.000000000000000000000000000000007266 132.0
TLS3_k127_4244854_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 1.919e-204 653.0
TLS3_k127_4244854_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000003627 244.0
TLS3_k127_4244854_11 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000001221 222.0
TLS3_k127_4244854_13 - - - - 0.0000002627 59.0
TLS3_k127_4244854_2 KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 512.0
TLS3_k127_4244854_3 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 412.0
TLS3_k127_4244854_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 374.0
TLS3_k127_4244854_5 Short-chain dehydrogenase reductase SDR K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 327.0
TLS3_k127_4244854_6 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 327.0
TLS3_k127_4244854_7 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 304.0
TLS3_k127_4244854_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004513 263.0
TLS3_k127_4244854_9 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000006624 271.0
TLS3_k127_4264732_0 PBS lyase HEAT-like repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 394.0
TLS3_k127_4264732_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 394.0
TLS3_k127_4264732_3 serine-type endopeptidase activity - - - 0.0000000002719 72.0
TLS3_k127_4279027_0 Molecular chaperone. Has ATPase activity K04079 - - 2.659e-298 941.0
TLS3_k127_4279027_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 7.652e-282 894.0
TLS3_k127_4279027_2 synthase homocitrate synthase family - - - 5.439e-230 726.0
TLS3_k127_4279027_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 459.0
TLS3_k127_4279027_4 Dienelactone hydrolase family K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 463.0
TLS3_k127_4279027_5 Ferritin-like domain K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 314.0
TLS3_k127_4279027_6 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000581 239.0
TLS3_k127_4279027_7 Patatin-like phospholipase K07001 - - 0.00000008995 64.0
TLS3_k127_429473_0 PFAM AMP-dependent synthetase and ligase K04110 - 6.2.1.25 2.335e-284 885.0
TLS3_k127_429473_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 7.051e-259 809.0
TLS3_k127_429473_10 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 534.0
TLS3_k127_429473_11 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 429.0
TLS3_k127_429473_12 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 362.0
TLS3_k127_429473_13 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 354.0
TLS3_k127_429473_14 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 329.0
TLS3_k127_429473_15 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005675 282.0
TLS3_k127_429473_16 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007947 257.0
TLS3_k127_429473_17 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000431 201.0
TLS3_k127_429473_18 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000005743 189.0
TLS3_k127_429473_19 alpha beta - - - 0.000000000000000000000000000000000000000000000001304 200.0
TLS3_k127_429473_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 9.907e-254 792.0
TLS3_k127_429473_20 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000006417 81.0
TLS3_k127_429473_21 - - - - 0.0000001396 56.0
TLS3_k127_429473_22 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.00005015 54.0
TLS3_k127_429473_23 - - - - 0.00005941 48.0
TLS3_k127_429473_3 alpha beta - - - 4.529e-246 779.0
TLS3_k127_429473_4 NADH oxidase - - - 5.845e-230 722.0
TLS3_k127_429473_5 protein kinase activity - - - 1.206e-226 722.0
TLS3_k127_429473_6 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 8.014e-220 687.0
TLS3_k127_429473_7 GMC oxidoreductase K00108 - 1.1.99.1 9.013e-218 685.0
TLS3_k127_429473_8 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 613.0
TLS3_k127_429473_9 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 548.0
TLS3_k127_4294821_0 Tex-like protein N-terminal domain K06959 - - 0.0 1190.0
TLS3_k127_4294821_1 Heat shock 70 kDa protein - - - 0.0 1103.0
TLS3_k127_4294821_2 Pyridoxal-dependent decarboxylase conserved domain K01580,K13745 - 4.1.1.15,4.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 604.0
TLS3_k127_4294821_3 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 443.0
TLS3_k127_4294821_4 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 383.0
TLS3_k127_4294821_6 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000002731 257.0
TLS3_k127_4294821_8 imidazolonepropionase K01468 - 3.5.2.7 0.000000001353 59.0
TLS3_k127_4294821_9 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.0000004274 62.0
TLS3_k127_429732_0 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001087 258.0
TLS3_k127_429732_4 peptidyl-prolyl cis-trans isomerase activity K00645,K02597,K03769,K03771 - 2.3.1.39,5.2.1.8 0.00000002224 65.0
TLS3_k127_4299400_0 Beta-eliminating lyase K00639 - 2.3.1.29 1.375e-271 846.0
TLS3_k127_4299400_1 response regulator K07714 - - 1.685e-251 780.0
TLS3_k127_4299400_2 Protein of unknown function (DUF3570) - - - 2.712e-236 746.0
TLS3_k127_4299400_4 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000000000000000000000000000000000000000000006536 234.0
TLS3_k127_4299400_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000006237 219.0
TLS3_k127_4299400_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000001992 172.0
TLS3_k127_4303010_0 AAA ATPase domain - - - 0.0 1045.0
TLS3_k127_4303010_2 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 369.0
TLS3_k127_4303010_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 295.0
TLS3_k127_4303010_5 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008504 249.0
TLS3_k127_4303010_6 Phosphoinositide phospholipase C, Ca2+-dependent - - - 0.000000000000000000000000000000000000000000000000000000002142 213.0
TLS3_k127_4303010_7 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000001414 201.0
TLS3_k127_4303010_9 pump membrane protein K03893 - - 0.00000000000000000003018 105.0
TLS3_k127_4309245_0 DNA helicase K03657 - 3.6.4.12 8.494e-317 987.0
TLS3_k127_4309245_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 1.172e-284 892.0
TLS3_k127_4309245_10 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 357.0
TLS3_k127_4309245_11 Vitamin K-dependent gamma-carboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 355.0
TLS3_k127_4309245_12 Alpha beta hydrolase K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000001825 253.0
TLS3_k127_4309245_13 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000000000000000000000000000000000000000001423 168.0
TLS3_k127_4309245_14 - - - - 0.000000000000000000000000000000000002593 145.0
TLS3_k127_4309245_16 Involved in molybdopterin and thiamine biosynthesis, family 2 K09136,K21029 - 2.7.7.80 0.0000000006215 63.0
TLS3_k127_4309245_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.727e-209 666.0
TLS3_k127_4309245_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 608.0
TLS3_k127_4309245_4 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 533.0
TLS3_k127_4309245_5 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 542.0
TLS3_k127_4309245_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 504.0
TLS3_k127_4309245_7 Male sterility protein K12454 - 5.1.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 492.0
TLS3_k127_4309245_8 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 445.0
TLS3_k127_4309245_9 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 411.0
TLS3_k127_4324939_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 434.0
TLS3_k127_4324939_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
TLS3_k127_4324939_2 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000001124 266.0
TLS3_k127_4324939_3 AI-2E family transporter - - - 0.0000000000000000000000000000000001367 136.0
TLS3_k127_4324939_4 Lipoprotein K05811 - - 0.00000000000000000001255 104.0
TLS3_k127_4345765_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0 1626.0
TLS3_k127_4345765_1 DNA helicase K03657 - 3.6.4.12 0.0 1095.0
TLS3_k127_4345765_12 GHMP kinase K00869,K07031 - 2.7.1.168,2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 320.0
TLS3_k127_4345765_13 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 314.0
TLS3_k127_4345765_14 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 290.0
TLS3_k127_4345765_15 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009867 274.0
TLS3_k127_4345765_16 PFAM Inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000236 284.0
TLS3_k127_4345765_17 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000123 267.0
TLS3_k127_4345765_18 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000005584 241.0
TLS3_k127_4345765_19 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000001743 203.0
TLS3_k127_4345765_2 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 481.0
TLS3_k127_4345765_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000048 169.0
TLS3_k127_4345765_23 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000005152 158.0
TLS3_k127_4345765_25 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000209 158.0
TLS3_k127_4345765_27 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000002656 137.0
TLS3_k127_4345765_28 - - - - 0.00000000000000000000000000006614 125.0
TLS3_k127_4345765_29 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000004178 128.0
TLS3_k127_4345765_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 456.0
TLS3_k127_4345765_31 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000004035 127.0
TLS3_k127_4345765_32 Acyltransferase - - - 0.00000000000000000000002222 111.0
TLS3_k127_4345765_36 - - - - 0.000000004276 61.0
TLS3_k127_4345765_37 Putative auto-transporter adhesin, head GIN domain - - - 0.00000001821 61.0
TLS3_k127_4345765_38 - - - - 0.0000002275 63.0
TLS3_k127_4345765_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 414.0
TLS3_k127_4345765_5 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 392.0
TLS3_k127_4345765_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 378.0
TLS3_k127_4345765_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 397.0
TLS3_k127_4345765_8 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 366.0
TLS3_k127_4345765_9 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 353.0
TLS3_k127_4368003_0 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 597.0
TLS3_k127_4368003_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 539.0
TLS3_k127_4368003_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 352.0
TLS3_k127_4368003_3 Uracil DNA glycosylase superfamily K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 314.0
TLS3_k127_4368003_5 TipAS antibiotic-recognition domain K21744 - - 0.00000000000000000000000000000000000000000000000006587 184.0
TLS3_k127_4368003_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000003985 174.0
TLS3_k127_4368003_7 cellulose binding K07279 - - 0.000000000756 68.0
TLS3_k127_4370379_0 Aminotransferase K01845 - 5.4.3.8 1.046e-209 658.0
TLS3_k127_4370379_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 489.0
TLS3_k127_4370379_2 FAD binding domain K05712,K16022 - 1.14.13.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 481.0
TLS3_k127_4370379_3 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 451.0
TLS3_k127_4370379_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 422.0
TLS3_k127_4370379_5 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 397.0
TLS3_k127_4370379_8 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000003177 178.0
TLS3_k127_4373541_0 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 566.0
TLS3_k127_4373541_1 Belongs to the peptidase S1B family K01183,K03791 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 587.0
TLS3_k127_4373541_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000005508 190.0
TLS3_k127_4373541_12 - - - - 0.000000008492 68.0
TLS3_k127_4373541_2 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 537.0
TLS3_k127_4373541_3 thiol oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 461.0
TLS3_k127_4373541_4 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 443.0
TLS3_k127_4373541_5 phosphorelay sensor kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 432.0
TLS3_k127_4373541_6 Belongs to the peptidase S1B family K04775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 411.0
TLS3_k127_4373541_7 iron ion transport K07224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 293.0
TLS3_k127_4373541_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000008847 217.0
TLS3_k127_4373809_0 Phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 498.0
TLS3_k127_4373809_1 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 439.0
TLS3_k127_4373809_10 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000344 168.0
TLS3_k127_4373809_11 - - - - 0.000000000000000000000000000000000997 149.0
TLS3_k127_4373809_12 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000003732 147.0
TLS3_k127_4373809_13 - - - - 0.0000000000000000000005945 111.0
TLS3_k127_4373809_14 oxidoreductase activity K07114 - - 0.00000000000000000000357 98.0
TLS3_k127_4373809_15 protein conserved in bacteria K11904 - - 0.00000000007669 70.0
TLS3_k127_4373809_16 Domain of unknown function (DUF4915) - - - 0.0002819 51.0
TLS3_k127_4373809_2 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 367.0
TLS3_k127_4373809_3 Sh3 type 3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 343.0
TLS3_k127_4373809_4 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 297.0
TLS3_k127_4373809_5 PFAM VanW family protein K18346 - - 0.00000000000000000000000000000000000000000000000000000000000000002078 243.0
TLS3_k127_4373809_6 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000001096 229.0
TLS3_k127_4373809_7 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000001929 200.0
TLS3_k127_4373809_9 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000105 181.0
TLS3_k127_4409628_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.561e-228 715.0
TLS3_k127_4409628_1 Belongs to the ompA family K20276 - - 5.427e-218 694.0
TLS3_k127_4409628_11 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000002198 215.0
TLS3_k127_4409628_12 - - - - 0.0000000000004532 74.0
TLS3_k127_4409628_2 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 599.0
TLS3_k127_4409628_3 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 421.0
TLS3_k127_4409628_4 2-dehydropantoate 2-reductase activity K00077,K04940 - 1.1.1.169,1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 366.0
TLS3_k127_4409628_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 347.0
TLS3_k127_4409628_6 COG1045 Serine acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004312 265.0
TLS3_k127_4409628_7 Peptidase M15 K02395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002702 264.0
TLS3_k127_4409628_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004369 251.0
TLS3_k127_4409628_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000348 235.0
TLS3_k127_4415098_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1183.0
TLS3_k127_4415098_1 AMP-binding enzyme K01897 - 6.2.1.3 4.195e-283 880.0
TLS3_k127_4415098_10 adenylate kinase activity K00939,K01939 - 2.7.4.3,6.3.4.4 0.00000000000000000000000000211 124.0
TLS3_k127_4415098_11 Thiamine biosynthesis K03154 - - 0.0000000000000000000001292 98.0
TLS3_k127_4415098_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 8.028e-197 625.0
TLS3_k127_4415098_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 545.0
TLS3_k127_4415098_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 494.0
TLS3_k127_4415098_5 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 389.0
TLS3_k127_4415098_6 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002453 287.0
TLS3_k127_4415098_7 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002965 246.0
TLS3_k127_4415098_8 Bacterial Ig-like domain (group 1) - - - 0.000000000000000000000000000000000004774 147.0
TLS3_k127_4415098_9 - - - - 0.0000000000000000000000000003284 118.0
TLS3_k127_4421125_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 421.0
TLS3_k127_4421125_1 Transcriptional regulator K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 374.0
TLS3_k127_4421125_10 - - - - 0.00000000000000000000000000000000002762 139.0
TLS3_k127_4421125_11 KaiC K08482 - - 0.000000000000000000000000000005506 123.0
TLS3_k127_4421125_13 PFAM response regulator receiver - - - 0.000001624 53.0
TLS3_k127_4421125_2 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 354.0
TLS3_k127_4421125_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000009244 242.0
TLS3_k127_4421125_4 Protein of unknown function (DUF1275) - - - 0.00000000000000000000000000000000000000000000000000000000000000146 229.0
TLS3_k127_4421125_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000000000000001769 191.0
TLS3_k127_4421125_6 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000003406 174.0
TLS3_k127_4421125_7 - - - - 0.000000000000000000000000000000000000005504 154.0
TLS3_k127_4421125_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000002308 151.0
TLS3_k127_4421125_9 Histidine kinase - - - 0.00000000000000000000000000000000001618 151.0
TLS3_k127_4426637_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 456.0
TLS3_k127_4426637_1 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 314.0
TLS3_k127_4426637_2 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001944 272.0
TLS3_k127_4426637_3 Beta-L-arabinofuranosidase, GH127 - - - 0.00004552 55.0
TLS3_k127_4428854_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0 1016.0
TLS3_k127_4428854_1 Parallel beta-helix repeats - - - 9.818e-228 732.0
TLS3_k127_4428854_11 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000007528 231.0
TLS3_k127_4428854_12 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000001155 237.0
TLS3_k127_4428854_13 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01654,K15898 - 2.5.1.56,2.5.1.97 0.000000000000000000000000000000000000000000000000000000001885 209.0
TLS3_k127_4428854_15 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000002327 196.0
TLS3_k127_4428854_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000433 170.0
TLS3_k127_4428854_17 NAD(P)H-binding - - - 0.0000000000000000000000000000004532 132.0
TLS3_k127_4428854_18 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000003187 129.0
TLS3_k127_4428854_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 513.0
TLS3_k127_4428854_21 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000002803 91.0
TLS3_k127_4428854_22 cellulase activity - - - 0.000000000009607 72.0
TLS3_k127_4428854_23 UbiA prenyltransferase family - - - 0.00002226 57.0
TLS3_k127_4428854_24 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000398 49.0
TLS3_k127_4428854_25 Carotenoid biosynthesis protein - - - 0.0001438 55.0
TLS3_k127_4428854_3 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 460.0
TLS3_k127_4428854_4 Domain of unknown function (DUF4343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 440.0
TLS3_k127_4428854_5 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 465.0
TLS3_k127_4428854_6 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 437.0
TLS3_k127_4428854_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 331.0
TLS3_k127_4428854_8 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 342.0
TLS3_k127_4428854_9 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 307.0
TLS3_k127_443041_0 Pentapeptide repeat protein - - - 3.64e-243 780.0
TLS3_k127_443041_1 Phage late control gene D protein (GPD) K11904 - - 3.299e-227 730.0
TLS3_k127_443041_10 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 373.0
TLS3_k127_443041_11 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 361.0
TLS3_k127_443041_12 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 333.0
TLS3_k127_443041_13 AMP-binding enzyme K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009202 287.0
TLS3_k127_443041_14 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000004159 268.0
TLS3_k127_443041_15 Protein of unknown function (DUF3540) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002185 236.0
TLS3_k127_443041_16 of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000002402 236.0
TLS3_k127_443041_17 Domain of unknown function (DUF4150) - - - 0.00000000000000000000000000000000000000001658 156.0
TLS3_k127_443041_18 Heavy-metal resistance - - - 0.000000000000000000000000000000000000002317 155.0
TLS3_k127_443041_19 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000000002896 161.0
TLS3_k127_443041_2 IgGFc binding protein - - - 5.15e-223 706.0
TLS3_k127_443041_3 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 526.0
TLS3_k127_443041_4 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 494.0
TLS3_k127_443041_5 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 488.0
TLS3_k127_443041_6 membrane protein involved in D-alanine export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 416.0
TLS3_k127_443041_7 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 393.0
TLS3_k127_443041_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 404.0
TLS3_k127_443041_9 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 374.0
TLS3_k127_4461604_0 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 531.0
TLS3_k127_4461604_1 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 520.0
TLS3_k127_4461604_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 488.0
TLS3_k127_4461604_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 305.0
TLS3_k127_4461604_5 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000004965 239.0
TLS3_k127_4461604_6 - - - - 0.00000000000000000000000000000000000000000000000000000000006895 214.0
TLS3_k127_4461604_7 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000004211 223.0
TLS3_k127_4466145_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1715.0
TLS3_k127_4466145_1 TonB dependent receptor - - - 0.0 1254.0
TLS3_k127_4466145_10 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 329.0
TLS3_k127_4466145_11 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 323.0
TLS3_k127_4466145_12 LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 311.0
TLS3_k127_4466145_13 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 304.0
TLS3_k127_4466145_14 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000028 266.0
TLS3_k127_4466145_15 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000011 244.0
TLS3_k127_4466145_16 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001413 242.0
TLS3_k127_4466145_17 FHA domain - - - 0.0000000000000000000000000000000000000000000000000000000000001395 241.0
TLS3_k127_4466145_18 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000003141 211.0
TLS3_k127_4466145_19 Phenazine biosynthesis protein A/B K06893 - - 0.0000000000000000000000000000000000000000000000000000008117 199.0
TLS3_k127_4466145_2 MMPL family - - - 2.634e-315 986.0
TLS3_k127_4466145_21 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000004911 156.0
TLS3_k127_4466145_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000001719 141.0
TLS3_k127_4466145_23 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000004221 111.0
TLS3_k127_4466145_25 DoxX-like family - - - 0.00000000000000006784 86.0
TLS3_k127_4466145_27 Putative metallopeptidase domain - - - 0.0000000000000006343 91.0
TLS3_k127_4466145_28 - - - - 0.0000000003124 74.0
TLS3_k127_4466145_29 CDP-alcohol phosphatidyltransferase - - - 0.00008669 54.0
TLS3_k127_4466145_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.989e-259 823.0
TLS3_k127_4466145_4 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 563.0
TLS3_k127_4466145_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 490.0
TLS3_k127_4466145_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 413.0
TLS3_k127_4466145_7 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 363.0
TLS3_k127_4466145_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 355.0
TLS3_k127_4466145_9 Phenazine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 353.0
TLS3_k127_4476172_0 oxidoreductase activity K07114 - - 5.161e-215 685.0
TLS3_k127_4476172_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 410.0
TLS3_k127_4476172_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 271.0
TLS3_k127_4476172_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000001977 210.0
TLS3_k127_4476172_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000525 197.0
TLS3_k127_448491_0 Oligonucleotide/oligosaccharide-binding (OB)-fold K03578,K03579 - 3.6.4.13 0.0 1760.0
TLS3_k127_448491_1 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 2.065e-321 997.0
TLS3_k127_448491_10 protein conserved in cyanobacteria - - - 0.000000000000000000002938 102.0
TLS3_k127_448491_11 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000643 101.0
TLS3_k127_448491_12 SnoaL-like domain K01822 - 5.3.3.1 0.0000000003012 68.0
TLS3_k127_448491_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 293.0
TLS3_k127_448491_3 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768,K03320 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001617 268.0
TLS3_k127_448491_5 Kelch motif - - - 0.00000000000000000000000000000000000000000000000001802 200.0
TLS3_k127_448491_6 - - - - 0.000000000000000000000000000000000000000000007074 172.0
TLS3_k127_448491_7 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000007655 149.0
TLS3_k127_448491_8 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000002432 131.0
TLS3_k127_448491_9 AI-2E family transporter - - - 0.0000000000000000000000004653 122.0
TLS3_k127_4495342_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 540.0
TLS3_k127_4495342_1 3-oxoacyl-[acyl-carrier-protein] synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004739 277.0
TLS3_k127_4499149_0 - - - - 0.0000000000000000000000000000000000000000000000000000006184 209.0
TLS3_k127_4499149_1 radical SAM domain protein - - - 0.0000000000000000000000000000006361 142.0
TLS3_k127_4499149_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000009502 121.0
TLS3_k127_4499149_3 radical SAM domain protein - - - 0.000006891 59.0
TLS3_k127_4499547_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1668.0
TLS3_k127_4499547_1 Circularly permuted ATP-grasp type 2 - - - 1.205e-245 774.0
TLS3_k127_4499547_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000074 284.0
TLS3_k127_4499547_13 - - - - 0.00000000000000000000000000000000000000000000000000000008223 201.0
TLS3_k127_4499547_14 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000002422 201.0
TLS3_k127_4499547_16 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000000000000000000000001402 153.0
TLS3_k127_4499547_17 Transglycosylase associated protein - - - 0.0000000000000000000000000000003 141.0
TLS3_k127_4499547_18 - - - - 0.0000000000000001578 95.0
TLS3_k127_4499547_19 Belongs to the peptidase S8 family - - - 0.0000000001654 67.0
TLS3_k127_4499547_2 AMP-binding enzyme K12508 - 6.2.1.34 1.165e-225 714.0
TLS3_k127_4499547_20 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000002993 72.0
TLS3_k127_4499547_22 phosphorelay signal transduction system - - - 0.00002597 51.0
TLS3_k127_4499547_24 Domain with 2 conserved Trp (W) residues - - - 0.00006147 54.0
TLS3_k127_4499547_3 PFAM MscS Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 548.0
TLS3_k127_4499547_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 545.0
TLS3_k127_4499547_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 455.0
TLS3_k127_4499547_6 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 433.0
TLS3_k127_4499547_7 Aldose 1-epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 365.0
TLS3_k127_4499547_8 Zinc-dependent metalloprotease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 306.0
TLS3_k127_4499547_9 conserved protein (DUF2267) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006767 285.0
TLS3_k127_4521379_0 serine threonine protein kinase - - - 0.0 1275.0
TLS3_k127_4521379_1 TIGRFAM YD repeat protein - - - 1.375e-287 926.0
TLS3_k127_4521379_10 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 473.0
TLS3_k127_4521379_11 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 450.0
TLS3_k127_4521379_12 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 387.0
TLS3_k127_4521379_13 PFAM NAD dependent epimerase dehydratase family K01784,K08678 - 4.1.1.35,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 344.0
TLS3_k127_4521379_14 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 318.0
TLS3_k127_4521379_15 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 310.0
TLS3_k127_4521379_16 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 307.0
TLS3_k127_4521379_17 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000004189 237.0
TLS3_k127_4521379_19 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000003788 203.0
TLS3_k127_4521379_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.538e-229 729.0
TLS3_k127_4521379_20 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000002167 183.0
TLS3_k127_4521379_21 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000004494 166.0
TLS3_k127_4521379_24 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000000000003389 123.0
TLS3_k127_4521379_25 - - - - 0.00000000000000000000003491 108.0
TLS3_k127_4521379_26 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000004323 87.0
TLS3_k127_4521379_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 1.656e-205 645.0
TLS3_k127_4521379_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 606.0
TLS3_k127_4521379_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 600.0
TLS3_k127_4521379_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 601.0
TLS3_k127_4521379_7 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 548.0
TLS3_k127_4521379_8 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 535.0
TLS3_k127_4521379_9 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 500.0
TLS3_k127_452264_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 9.101e-198 629.0
TLS3_k127_452264_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000112 271.0
TLS3_k127_452264_2 TQO small subunit DoxA K16936,K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000007448 264.0
TLS3_k127_452264_3 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000006169 235.0
TLS3_k127_452264_4 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000002927 228.0
TLS3_k127_452264_5 Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000001232 147.0
TLS3_k127_4524499_0 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 482.0
TLS3_k127_4524499_1 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 482.0
TLS3_k127_4524499_10 Anti-sigma regulatory factor (Ser Thr protein kinase) K17752 - 2.7.11.1 0.000000000000000000000000000000002161 140.0
TLS3_k127_4524499_12 antisigma factor binding K17762 - - 0.000000000000000000000000001427 121.0
TLS3_k127_4524499_2 Ketopantoate reductase PanE/ApbA K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 423.0
TLS3_k127_4524499_3 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 393.0
TLS3_k127_4524499_4 ERAP1-like C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 311.0
TLS3_k127_4524499_5 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000444 287.0
TLS3_k127_4524499_6 STAS domain K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005455 251.0
TLS3_k127_4524499_7 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000003243 217.0
TLS3_k127_4524499_8 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000003085 194.0
TLS3_k127_4524499_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000001032 182.0
TLS3_k127_4534285_0 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.0 1023.0
TLS3_k127_4534285_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 568.0
TLS3_k127_4534285_10 SCP-2 sterol transfer family - - - 0.0000000000000000000002603 98.0
TLS3_k127_4534285_11 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K01647,K22491 - 2.3.3.1 0.000000000000000000009749 98.0
TLS3_k127_4534285_12 protein kinase activity - - - 0.00000000000001168 82.0
TLS3_k127_4534285_13 Sel1-like repeats. K07126 - - 0.000000000000947 76.0
TLS3_k127_4534285_14 - - - - 0.000000000004276 71.0
TLS3_k127_4534285_15 Protein of unknown function (DUF1552) - - - 0.000000003911 69.0
TLS3_k127_4534285_16 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000008278 48.0
TLS3_k127_4534285_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 445.0
TLS3_k127_4534285_3 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 401.0
TLS3_k127_4534285_4 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003442 280.0
TLS3_k127_4534285_5 PFAM Sel1 domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001895 277.0
TLS3_k127_4534285_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004429 243.0
TLS3_k127_4534285_7 photosystem II stabilization K02237 - - 0.00000000000000000000000000000000000000000000000000000000001829 225.0
TLS3_k127_4534285_9 Limonene-1,2-epoxide hydrolase catalytic domain K10533 GO:0003674,GO:0003824,GO:0004301,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016801,GO:0016803,GO:0018904,GO:0033963,GO:0044237,GO:0044281,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0097176,GO:1901360 3.3.2.8 0.0000000000000000000000000000001998 134.0
TLS3_k127_4540840_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 358.0
TLS3_k127_4540840_1 protein containing a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000007376 198.0
TLS3_k127_4540840_2 domain, Protein - - - 0.00000000000000000000000000000000000000007097 168.0
TLS3_k127_4540840_3 mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000001206 143.0
TLS3_k127_4540840_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000743 128.0
TLS3_k127_4540840_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000611 106.0
TLS3_k127_4546695_0 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 4.255e-195 619.0
TLS3_k127_4546695_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 385.0
TLS3_k127_4546695_3 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 334.0
TLS3_k127_4546695_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 334.0
TLS3_k127_4546695_5 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001687 260.0
TLS3_k127_4546695_6 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000002955 226.0
TLS3_k127_4546695_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000002701 114.0
TLS3_k127_4550291_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2188.0
TLS3_k127_4550291_1 Pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 2.225e-226 711.0
TLS3_k127_4550291_2 Mo-co oxidoreductase dimerisation domain K00387 - 1.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 342.0
TLS3_k127_4550291_3 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002932 268.0
TLS3_k127_4550291_5 Domain of unknown function (DUF2382) - - - 0.00000000000000000000000000000000000000003581 163.0
TLS3_k127_4550291_6 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000003785 142.0
TLS3_k127_4550291_7 Cytochrome c K03889 - - 0.000000000000000000003689 106.0
TLS3_k127_4550291_9 PFAM Ig domain protein group 2 domain protein - - - 0.0000003475 60.0
TLS3_k127_4552846_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 481.0
TLS3_k127_4552846_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 336.0
TLS3_k127_4552846_2 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000006593 127.0
TLS3_k127_4572134_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 4.38e-229 737.0
TLS3_k127_4572134_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 3.087e-228 737.0
TLS3_k127_4572134_2 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.705e-196 623.0
TLS3_k127_4572134_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 552.0
TLS3_k127_4572134_4 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 349.0
TLS3_k127_4572134_5 PFAM Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 314.0
TLS3_k127_4572134_6 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000004843 267.0
TLS3_k127_4572134_7 InterPro IPR007367 - - - 0.00000000000000000000000000000000000000000000000000003347 194.0
TLS3_k127_4578609_0 DEAD DEAH box helicase - - - 0.0 1170.0
TLS3_k127_4578609_1 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 2.044e-294 922.0
TLS3_k127_4578609_10 serine threonine protein kinase - - - 0.00002199 52.0
TLS3_k127_4578609_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 9.415e-237 752.0
TLS3_k127_4578609_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 325.0
TLS3_k127_4578609_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001046 237.0
TLS3_k127_4578609_6 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000007774 181.0
TLS3_k127_4578609_7 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000000000001974 140.0
TLS3_k127_4578609_8 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000002993 127.0
TLS3_k127_4589363_0 coenzyme F390 K01912 - 6.2.1.30 0.0 1233.0
TLS3_k127_4589363_1 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 587.0
TLS3_k127_4589363_10 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000005158 244.0
TLS3_k127_4589363_11 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001298 229.0
TLS3_k127_4589363_12 peptidyl-prolyl cis-trans isomerase activity K01802,K03769 - 5.2.1.8 0.000000000000000000000007304 115.0
TLS3_k127_4589363_13 - - - - 0.00000000000000005034 84.0
TLS3_k127_4589363_14 Methyltransferase domain K14374,K18896 - 2.1.1.156 0.000000000000005181 85.0
TLS3_k127_4589363_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 514.0
TLS3_k127_4589363_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 398.0
TLS3_k127_4589363_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 383.0
TLS3_k127_4589363_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 377.0
TLS3_k127_4589363_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 305.0
TLS3_k127_4589363_7 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 312.0
TLS3_k127_4589363_9 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002038 252.0
TLS3_k127_4591596_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.979e-268 841.0
TLS3_k127_4591596_1 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 605.0
TLS3_k127_4591596_10 - - - - 0.0000000000000000000000000001147 127.0
TLS3_k127_4591596_11 Parallel beta-helix repeats - - - 0.000000000182 67.0
TLS3_k127_4591596_2 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 479.0
TLS3_k127_4591596_3 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 435.0
TLS3_k127_4591596_4 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 365.0
TLS3_k127_4591596_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 307.0
TLS3_k127_4591596_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000001488 221.0
TLS3_k127_4591596_7 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000001805 160.0
TLS3_k127_4591596_8 PAS fold - - - 0.000000000000000000000000000000001118 139.0
TLS3_k127_4591596_9 FHA domain - - - 0.00000000000000000000000000005516 126.0
TLS3_k127_459571_0 AcrB/AcrD/AcrF family K03296 - - 2.114e-296 941.0
TLS3_k127_459571_1 protein conserved in bacteria K11904 - - 6.64e-271 862.0
TLS3_k127_459571_10 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 485.0
TLS3_k127_459571_11 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 434.0
TLS3_k127_459571_12 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 417.0
TLS3_k127_459571_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 374.0
TLS3_k127_459571_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 317.0
TLS3_k127_459571_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 305.0
TLS3_k127_459571_16 beta-ketoacyl-acyl-carrier-protein synthase II activity K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001909 295.0
TLS3_k127_459571_17 RNA pseudouridylate synthase K06175 - 5.4.99.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000271 280.0
TLS3_k127_459571_18 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000069 278.0
TLS3_k127_459571_19 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005344 291.0
TLS3_k127_459571_2 protein conserved in bacteria K11904 - - 1.295e-254 805.0
TLS3_k127_459571_20 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000882 261.0
TLS3_k127_459571_21 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005438 244.0
TLS3_k127_459571_22 COG3911 Predicted ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000001182 235.0
TLS3_k127_459571_23 cytochrome c oxidase K00405 - - 0.0000000000000000000000000000000000000000000000000000000000009694 216.0
TLS3_k127_459571_24 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000449 228.0
TLS3_k127_459571_25 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000001726 197.0
TLS3_k127_459571_26 - - - - 0.000000000000000000000000000000000000000001093 168.0
TLS3_k127_459571_27 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000004967 147.0
TLS3_k127_459571_28 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000001133 145.0
TLS3_k127_459571_3 Histidine kinase K07716 - 2.7.13.3 2.602e-235 744.0
TLS3_k127_459571_30 Peptidase family M50 - - - 0.0000000000000000000000000002777 129.0
TLS3_k127_459571_32 Protein of unknown function (DUF2892) - - - 0.000000000000002827 79.0
TLS3_k127_459571_33 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000008766 73.0
TLS3_k127_459571_35 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0003874 48.0
TLS3_k127_459571_4 protein conserved in bacteria K11904 - - 1.911e-229 733.0
TLS3_k127_459571_5 Beta-Casp domain K07576 - - 1.465e-222 698.0
TLS3_k127_459571_6 AAA domain K01551 - 3.6.3.16 9.017e-217 689.0
TLS3_k127_459571_7 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 598.0
TLS3_k127_459571_8 COGs COG3278 Cbb3-type cytochrome oxidase subunit 1 K00404,K15862 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 553.0
TLS3_k127_459571_9 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 498.0
TLS3_k127_4596850_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1182.0
TLS3_k127_4596850_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 1.941e-270 848.0
TLS3_k127_4596850_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 527.0
TLS3_k127_4596850_3 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 443.0
TLS3_k127_4596850_4 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000002705 179.0
TLS3_k127_4596850_5 COGs COG2149 membrane protein K00389 - - 0.0000000000000001004 88.0
TLS3_k127_4596850_6 Proposed nucleic acid binding domain - - - 0.00000000000001045 85.0
TLS3_k127_4596850_7 PFAM Glycosyl hydrolases family 15 - - - 0.00000000003359 67.0
TLS3_k127_4596850_8 Fibronectin type 3 domain K05717,K06252 - - 0.0000161 54.0
TLS3_k127_4610863_0 Alkaline phosphatase K01113 - 3.1.3.1 2.092e-196 631.0
TLS3_k127_4610863_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 524.0
TLS3_k127_4610863_10 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 287.0
TLS3_k127_4610863_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005656 255.0
TLS3_k127_4610863_12 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002267 253.0
TLS3_k127_4610863_13 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001544 222.0
TLS3_k127_4610863_14 extracellular polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000001789 208.0
TLS3_k127_4610863_15 methyltransferase - - - 0.00000000000000000000000000000000000000000000003062 182.0
TLS3_k127_4610863_16 -O-antigen K02847 - - 0.000000000000000000000000000000000000000001482 173.0
TLS3_k127_4610863_17 polysaccharide export K01991 - - 0.0000000000000000000000000000000000001835 153.0
TLS3_k127_4610863_18 - - - - 0.00000000000000000000000000000000004425 144.0
TLS3_k127_4610863_19 O-acyltransferase activity K00661 - 2.3.1.79 0.000000000000000000000001344 111.0
TLS3_k127_4610863_2 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 493.0
TLS3_k127_4610863_20 O-acyltransferase activity K00661 - 2.3.1.79 0.000000000000000000000002132 111.0
TLS3_k127_4610863_21 Predicted membrane protein (DUF2085) - - - 0.000000000000000000005338 98.0
TLS3_k127_4610863_24 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000009045 95.0
TLS3_k127_4610863_25 - - - - 0.00000000000000005754 94.0
TLS3_k127_4610863_26 PFAM response regulator receiver K03413 - - 0.000000000000000342 86.0
TLS3_k127_4610863_27 - - - - 0.0000000000000006141 88.0
TLS3_k127_4610863_28 Protein of unknown function (DUF2752) - - - 0.00000000005759 69.0
TLS3_k127_4610863_29 Bacterial protein of unknown function (DUF898) - - - 0.0000000001895 74.0
TLS3_k127_4610863_3 Glyco_18 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 474.0
TLS3_k127_4610863_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 413.0
TLS3_k127_4610863_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 392.0
TLS3_k127_4610863_6 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 360.0
TLS3_k127_4610863_7 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 343.0
TLS3_k127_4610863_8 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 314.0
TLS3_k127_4610863_9 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 302.0
TLS3_k127_4612972_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.961e-270 848.0
TLS3_k127_4612972_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 5.123e-197 633.0
TLS3_k127_4612972_2 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 458.0
TLS3_k127_4612972_3 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 456.0
TLS3_k127_4612972_4 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 350.0
TLS3_k127_4612972_5 K+-transporting ATPase, c chain K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000566 184.0
TLS3_k127_4612972_7 Histidine kinase - - - 0.00000003141 64.0
TLS3_k127_4612972_8 Bacterial regulatory protein, Fis family - - - 0.00000003849 66.0
TLS3_k127_4615740_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 546.0
TLS3_k127_4615740_2 Belongs to the pseudouridine synthase RluA family K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 403.0
TLS3_k127_4615740_3 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 319.0
TLS3_k127_4615740_4 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 305.0
TLS3_k127_4615740_5 Extensin-like protein C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 301.0
TLS3_k127_4615740_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 295.0
TLS3_k127_4615740_7 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003475 265.0
TLS3_k127_4615740_9 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000009066 192.0
TLS3_k127_4625821_0 protein kinase activity - - - 5.855e-289 900.0
TLS3_k127_4625821_1 DNA helicase K03654 - 3.6.4.12 2.658e-265 858.0
TLS3_k127_4625821_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 370.0
TLS3_k127_4625821_3 4-vinyl reductase, 4VR - - - 0.00000000000000000000000000000000000000000000000000000000000006818 218.0
TLS3_k127_4625821_4 antisigma factor binding K17763 - - 0.000000000000000000000000000000000000001227 155.0
TLS3_k127_4627386_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003945 260.0
TLS3_k127_4627386_2 PFAM Formylglycine-generating sulfatase enzyme K08884,K20333 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001029 248.0
TLS3_k127_4648865_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001112 280.0
TLS3_k127_4648865_1 polysaccharide catabolic process K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000006962 259.0
TLS3_k127_4648865_2 - - - - 0.0000000000000000000000000000000000000000000000000000000003585 206.0
TLS3_k127_4648865_3 metal cluster binding - - - 0.000000000000000000000000002502 127.0
TLS3_k127_465413_0 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 6.345e-229 728.0
TLS3_k127_465413_1 COG0515 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 591.0
TLS3_k127_465413_2 Anti-anti sigma factor protein K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 560.0
TLS3_k127_465413_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001669 263.0
TLS3_k127_4659643_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1219.0
TLS3_k127_4659643_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 6.829e-293 907.0
TLS3_k127_4659643_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 2.162e-271 854.0
TLS3_k127_4659643_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 602.0
TLS3_k127_4659643_4 Glycoside-hydrolase family GH114 K21006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 337.0
TLS3_k127_4659643_5 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000001694 225.0
TLS3_k127_4659643_7 cellulose binding - - - 0.0000000000006138 81.0
TLS3_k127_4663664_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 8.345e-308 959.0
TLS3_k127_4663664_1 - - - - 9.905e-198 629.0
TLS3_k127_4663664_2 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 478.0
TLS3_k127_4663664_3 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 469.0
TLS3_k127_4663664_4 Belongs to the glycosyl hydrolase family 6 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 323.0
TLS3_k127_4663664_5 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008582 267.0
TLS3_k127_4663664_7 Type VI secretion system effector, Hcp K11903 - - 0.000000008631 57.0
TLS3_k127_4687531_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 3.086e-309 960.0
TLS3_k127_4687531_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.878e-266 831.0
TLS3_k127_4687531_10 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 403.0
TLS3_k127_4687531_11 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 398.0
TLS3_k127_4687531_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 382.0
TLS3_k127_4687531_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 381.0
TLS3_k127_4687531_14 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 369.0
TLS3_k127_4687531_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 333.0
TLS3_k127_4687531_16 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 333.0
TLS3_k127_4687531_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 289.0
TLS3_k127_4687531_19 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 288.0
TLS3_k127_4687531_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 7.274e-244 767.0
TLS3_k127_4687531_20 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004353 278.0
TLS3_k127_4687531_21 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001381 260.0
TLS3_k127_4687531_22 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000004513 248.0
TLS3_k127_4687531_24 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000008 204.0
TLS3_k127_4687531_25 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000002797 207.0
TLS3_k127_4687531_28 cell adhesion involved in biofilm formation - - - 0.00000000000003089 82.0
TLS3_k127_4687531_29 Fc fragment of IgE, low affinity II, receptor for (CD23) K06468 GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002703,GO:0002705,GO:0002706,GO:0002708,GO:0002712,GO:0002714,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0002889,GO:0002891,GO:0002920,GO:0002922,GO:0002923,GO:0002925,GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0010556,GO:0010557,GO:0010604,GO:0016020,GO:0016021,GO:0019221,GO:0019222,GO:0023052,GO:0031224,GO:0031226,GO:0031341,GO:0031343,GO:0032768,GO:0032770,GO:0034097,GO:0042221,GO:0043085,GO:0043900,GO:0043902,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0044877,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050839,GO:0050896,GO:0050999,GO:0051000,GO:0051341,GO:0051353,GO:0051709,GO:0051712,GO:0051716,GO:0051769,GO:0051770,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071310,GO:0071345,GO:0071944,GO:0098552 - 0.0000000144 65.0
TLS3_k127_4687531_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 1.097e-237 737.0
TLS3_k127_4687531_30 PFAM Polyketide cyclase dehydrase - - - 0.00005235 51.0
TLS3_k127_4687531_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 1.734e-229 732.0
TLS3_k127_4687531_5 drug resistance transporter, EmrB QacA subfamily K03446 - - 5.226e-217 685.0
TLS3_k127_4687531_6 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 8.208e-215 685.0
TLS3_k127_4687531_8 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 608.0
TLS3_k127_4687531_9 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 476.0
TLS3_k127_469722_1 - - - - 0.0000000000000000000000000000000000000000000001436 177.0
TLS3_k127_469722_2 COG1061 DNA or RNA helicases of superfamily II - - - 0.000000000000000000000000000000000000000003243 164.0
TLS3_k127_4699816_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 5.736e-301 943.0
TLS3_k127_4699816_1 HD domain - - - 1.294e-275 852.0
TLS3_k127_4699816_2 Belongs to the aldehyde dehydrogenase family K00128,K00131,K00135,K00140 - 1.2.1.16,1.2.1.18,1.2.1.20,1.2.1.27,1.2.1.3,1.2.1.79,1.2.1.9 3.244e-217 683.0
TLS3_k127_4699816_3 type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 593.0
TLS3_k127_4699816_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 357.0
TLS3_k127_4699816_5 membrane K01317,K02343,K02666 - 2.7.7.7,3.4.21.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 354.0
TLS3_k127_4699816_6 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002947 256.0
TLS3_k127_4699816_7 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000000000000000000000005086 192.0
TLS3_k127_4699816_8 Belongs to the frataxin family K06202 - - 0.00000000000000000000000000000000004396 155.0
TLS3_k127_4699816_9 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000175 111.0
TLS3_k127_4727775_0 Tetratricopeptide repeat - - - 0.0 5089.0
TLS3_k127_4727775_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 457.0
TLS3_k127_4727775_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 451.0
TLS3_k127_4727775_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 369.0
TLS3_k127_4727775_4 Aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 358.0
TLS3_k127_4727775_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 351.0
TLS3_k127_4727775_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000329 263.0
TLS3_k127_4727775_7 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000004947 220.0
TLS3_k127_4727775_8 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000744 115.0
TLS3_k127_4762690_0 Family membership - - - 0.0 1392.0
TLS3_k127_4762690_10 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002444 241.0
TLS3_k127_4762690_11 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000007344 217.0
TLS3_k127_4762690_2 ABC-type uncharacterized transport system K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 616.0
TLS3_k127_4762690_3 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 465.0
TLS3_k127_4762690_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 408.0
TLS3_k127_4762690_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 368.0
TLS3_k127_4762690_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 373.0
TLS3_k127_4762690_8 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 292.0
TLS3_k127_4762690_9 YaeQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 286.0
TLS3_k127_477275_0 lysine 2,3-aminomutase K01843 - 5.4.3.2 2.572e-266 826.0
TLS3_k127_477275_1 synthase K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 565.0
TLS3_k127_477275_2 peptide catabolic process K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 556.0
TLS3_k127_477275_3 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 477.0
TLS3_k127_477275_4 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 382.0
TLS3_k127_477275_5 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 349.0
TLS3_k127_477275_6 CoA-transferase activity K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 332.0
TLS3_k127_477275_7 Transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 326.0
TLS3_k127_477275_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 293.0
TLS3_k127_4784071_0 HEAT repeats - - - 1.403e-307 971.0
TLS3_k127_4784071_1 - - - - 5.899e-259 813.0
TLS3_k127_4784071_10 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 291.0
TLS3_k127_4784071_11 Ergosterol biosynthesis ERG4/ERG24 family K00213 - 1.3.1.21 0.0000000000000000000000000000000000000000000000000000000000000000002457 237.0
TLS3_k127_4784071_12 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000002531 221.0
TLS3_k127_4784071_13 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000005125 180.0
TLS3_k127_4784071_14 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000000000000000000000000000000000002228 190.0
TLS3_k127_4784071_15 Acyl-transferase - - - 0.00000000000000000000000000000000000000000002614 173.0
TLS3_k127_4784071_16 RF-1 domain K15034 - - 0.0000000000000000000000000000000002198 144.0
TLS3_k127_4784071_2 ABC1 family - - - 9.009e-247 769.0
TLS3_k127_4784071_3 VWA domain containing CoxE-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 616.0
TLS3_k127_4784071_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 561.0
TLS3_k127_4784071_5 Choline/ethanolamine kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 434.0
TLS3_k127_4784071_6 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009033 460.0
TLS3_k127_4784071_7 KAP family P-loop domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 426.0
TLS3_k127_4784071_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 358.0
TLS3_k127_4784071_9 Putative esterase K07017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 299.0
TLS3_k127_4784504_0 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 527.0
TLS3_k127_4784504_1 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 518.0
TLS3_k127_4784504_2 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 467.0
TLS3_k127_4784504_3 Taurine catabolism dioxygenase TauD, TfdA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 402.0
TLS3_k127_4784504_4 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress K05916,K15765 GO:0000041,GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004155,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009987,GO:0015669,GO:0015671,GO:0015893,GO:0016491,GO:0016645,GO:0016646,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0030001,GO:0033554,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042493,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051213,GO:0051234,GO:0051409,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0071500,GO:0071949,GO:0072593,GO:0097159,GO:1901265,GO:1901363,GO:2001057 1.14.12.17,1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 338.0
TLS3_k127_4784504_5 thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
TLS3_k127_4784504_6 Pentapeptide repeat - - - 0.000000000000000005052 86.0
TLS3_k127_4788161_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 572.0
TLS3_k127_4788161_2 CHAP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 406.0
TLS3_k127_4788161_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 412.0
TLS3_k127_4788161_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 330.0
TLS3_k127_4795933_0 Belongs to the aldehyde dehydrogenase family - - - 6.239e-219 687.0
TLS3_k127_4795933_1 Belongs to the sigma-70 factor family - - - 1.108e-218 691.0
TLS3_k127_4795933_2 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 606.0
TLS3_k127_4795933_3 OmpA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 541.0
TLS3_k127_4795933_4 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 358.0
TLS3_k127_4795933_5 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009813 229.0
TLS3_k127_4795933_6 Negative regulator of - - - 0.00000000000000000000000000000000009205 151.0
TLS3_k127_4795933_7 - - - - 0.000000000000000001835 100.0
TLS3_k127_4795933_8 CarboxypepD_reg-like domain - - - 0.00000000002825 76.0
TLS3_k127_4796323_0 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 372.0
TLS3_k127_4796323_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002678 269.0
TLS3_k127_4796323_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000002175 250.0
TLS3_k127_4796323_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000001129 230.0
TLS3_k127_4799326_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1357.0
TLS3_k127_4799326_1 Surface antigen - - - 3.873e-221 698.0
TLS3_k127_4799326_10 Virulence protein SciE type K11898 - - 0.000000000001553 79.0
TLS3_k127_4799326_11 amine dehydrogenase activity - - - 0.0000001642 59.0
TLS3_k127_4799326_2 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 571.0
TLS3_k127_4799326_3 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 413.0
TLS3_k127_4799326_4 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 307.0
TLS3_k127_4799326_5 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 301.0
TLS3_k127_4799326_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 292.0
TLS3_k127_4799326_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 296.0
TLS3_k127_4799326_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004262 291.0
TLS3_k127_4799326_9 Putative NAD(P)-binding K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000003485 200.0
TLS3_k127_4806450_0 AAA ATPase domain - - - 1.502e-260 848.0
TLS3_k127_4806450_1 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 325.0
TLS3_k127_4806450_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000009162 211.0
TLS3_k127_4806450_3 AAA domain - - - 0.000000000000000000000000000000000000000000005649 179.0
TLS3_k127_4806450_4 AAA domain (dynein-related subfamily) K07452 - - 0.000000000000000000000000000000000006653 141.0
TLS3_k127_4806450_5 AAA domain (dynein-related subfamily) K07452 - - 0.00000000000000000000007138 112.0
TLS3_k127_4819952_0 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 7.258e-229 716.0
TLS3_k127_4819952_1 cytochrome C peroxidase - - - 2.214e-213 683.0
TLS3_k127_4819952_2 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 450.0
TLS3_k127_4819952_3 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000000000000001273 233.0
TLS3_k127_4819952_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000009992 221.0
TLS3_k127_4819952_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000004132 232.0
TLS3_k127_4822389_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.362e-248 771.0
TLS3_k127_4822389_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 419.0
TLS3_k127_4822389_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 336.0
TLS3_k127_4822389_3 Homologues of snake disintegrins - - - 0.00000000000000000000000000000000007946 149.0
TLS3_k127_4822389_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000003574 115.0
TLS3_k127_4822389_5 protein kinase activity - - - 0.000006434 48.0
TLS3_k127_4831220_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1086.0
TLS3_k127_4831220_1 SpoVR like protein K06415 - - 3.525e-309 951.0
TLS3_k127_4831220_10 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001683 263.0
TLS3_k127_4831220_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000004579 218.0
TLS3_k127_4831220_13 - - - - 0.00000000000000000000000000000000000000000000000007595 183.0
TLS3_k127_4831220_14 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000002233 194.0
TLS3_k127_4831220_15 phosphorelay signal transduction system - - - 0.0000000000000000000003473 102.0
TLS3_k127_4831220_16 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.000003326 59.0
TLS3_k127_4831220_18 Adenylate and Guanylate cyclase catalytic domain - - - 0.0001971 53.0
TLS3_k127_4831220_2 Carboxyl transferase domain - - - 2.309e-302 932.0
TLS3_k127_4831220_3 Belongs to the UPF0229 family K09786 - - 4.966e-222 695.0
TLS3_k127_4831220_4 Pfam:Kce - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 562.0
TLS3_k127_4831220_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 445.0
TLS3_k127_4831220_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 400.0
TLS3_k127_4831220_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 414.0
TLS3_k127_4831220_8 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 357.0
TLS3_k127_4831220_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 353.0
TLS3_k127_4831530_0 protein kinase activity - - - 2.586e-226 717.0
TLS3_k127_4831530_1 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 1.789e-211 676.0
TLS3_k127_4831530_3 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001261 270.0
TLS3_k127_4831530_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000001665 205.0
TLS3_k127_4831530_5 SWIM zinc finger - - - 0.00000000000000000006927 93.0
TLS3_k127_4831530_6 6-phosphogluconolactonase activity - - - 0.000006978 48.0
TLS3_k127_4833143_0 serine threonine protein kinase - - - 0.0 1687.0
TLS3_k127_4833143_1 PFAM SNF2-related protein K08282 - 2.7.11.1 7.2e-279 871.0
TLS3_k127_4833143_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 310.0
TLS3_k127_4833143_3 Zinc finger SWIM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000121 295.0
TLS3_k127_4833143_4 unfolded protein binding K06142 - - 0.000000000000000000000000000000000000000000000000000000000000000002835 237.0
TLS3_k127_4833143_6 - - - - 0.0000000000000000000000000000000000000000001256 164.0
TLS3_k127_4833143_7 COG1961 Site-specific recombinases, DNA invertase Pin homologs K06400 - - 0.000000000004827 78.0
TLS3_k127_4834010_2 Protein of unknown function (DUF1232) - - - 0.0000003712 57.0
TLS3_k127_4839998_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 6.372e-221 711.0
TLS3_k127_4839998_3 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 641.0
TLS3_k127_4839998_4 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 557.0
TLS3_k127_4839998_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 352.0
TLS3_k127_4839998_6 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 323.0
TLS3_k127_4839998_7 nuclease activity K06218,K07334 - - 0.0000000009142 63.0
TLS3_k127_4849015_0 von Willebrand factor type A domain - - - 0.0 1528.0
TLS3_k127_4849015_1 Aerotolerance regulator N-terminal - - - 1.081e-320 990.0
TLS3_k127_4849015_2 glutamate--cysteine ligase K01919 - 6.3.2.2 4.305e-218 685.0
TLS3_k127_4849015_3 Transporter associated domain - - - 6.398e-198 625.0
TLS3_k127_4849015_4 Von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 369.0
TLS3_k127_4849015_5 homocysteine K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000001781 264.0
TLS3_k127_4849015_6 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004369 261.0
TLS3_k127_4849015_8 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000006633 148.0
TLS3_k127_4870569_0 Alpha-amylase domain K01176 - 3.2.1.1 5.231e-213 677.0
TLS3_k127_4870569_1 Evidence 4 Homologs of previously reported genes of - - - 2.547e-207 654.0
TLS3_k127_4870569_2 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 6.503e-207 649.0
TLS3_k127_4870569_3 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 531.0
TLS3_k127_4870569_5 acetyltransferase K00619,K03830 - 2.3.1.1 0.000000000000000000000000000000000000000000000001865 183.0
TLS3_k127_4870569_6 Putative esterase - - - 0.000000000000000000000000002701 113.0
TLS3_k127_4923127_0 Phage late control gene D protein (GPD) K11904 - - 3.817e-230 739.0
TLS3_k127_4923127_1 Uncharacterized protein conserved in bacteria (DUF2169) - - - 9.271e-212 691.0
TLS3_k127_4923127_2 Pentapeptide repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 560.0
TLS3_k127_4923127_3 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000129 283.0
TLS3_k127_4923127_4 Pentapeptide repeats (9 copies) - - - 0.000000001377 66.0
TLS3_k127_4949054_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 366.0
TLS3_k127_4949054_1 Glycosyl hydrolases family 18 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002922 270.0
TLS3_k127_4949054_2 Chitinase class I K01183 - 3.2.1.14 0.0000000000000000000000000000000000004622 158.0
TLS3_k127_4949054_3 FAD linked oxidase domain protein - - - 0.000000001075 71.0
TLS3_k127_4956503_0 UPF0313 protein - - - 0.0 1104.0
TLS3_k127_4956503_1 Polyphosphate kinase 2 (PPK2) - - - 2.729e-210 668.0
TLS3_k127_4956503_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 508.0
TLS3_k127_4956503_3 - - - - 0.000000000000000000000000000000000008233 156.0
TLS3_k127_4956503_4 Serine aminopeptidase, S33 - - - 0.000000000000002198 79.0
TLS3_k127_5006068_0 Sugar ABC transporter permease K10109,K15770,K15771 - - 2.125e-296 930.0
TLS3_k127_5006068_1 Dienelactone hydrolase family - - - 1.105e-290 907.0
TLS3_k127_5006068_11 Homologues of snake disintegrins - - - 0.000000000000000001061 101.0
TLS3_k127_5006068_2 Alpha-amylase domain - - - 2.173e-246 775.0
TLS3_k127_5006068_3 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02017,K02045,K15497 - 3.6.3.25,3.6.3.29,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 552.0
TLS3_k127_5006068_4 maltodextrin transmembrane transporter activity K02024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 554.0
TLS3_k127_5006068_5 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 467.0
TLS3_k127_5006068_6 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 432.0
TLS3_k127_5006068_7 TOBE domain K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008668 358.0
TLS3_k127_5006068_8 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 335.0
TLS3_k127_5006068_9 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000001028 229.0
TLS3_k127_5019565_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1039.0
TLS3_k127_5019565_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.595e-259 816.0
TLS3_k127_5019565_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 292.0
TLS3_k127_5030728_0 Sulfatase-modifying factor enzyme 1 K08884,K12132 - 2.7.11.1 0.0 1070.0
TLS3_k127_5030728_1 Ribonuclease E/G family K08301 - - 1.012e-287 908.0
TLS3_k127_5030728_10 PilZ domain - - - 0.000000000000000000000000000000000000000000002809 184.0
TLS3_k127_5030728_11 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.000000000000000000000000000000000000000001022 173.0
TLS3_k127_5030728_12 regulator of chromosome condensation, RCC1 - - - 0.000002598 58.0
TLS3_k127_5030728_2 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 4.72e-282 878.0
TLS3_k127_5030728_3 Protein kinase domain K12132 - 2.7.11.1 2.246e-236 752.0
TLS3_k127_5030728_4 transcription factor binding - - - 4.47e-201 636.0
TLS3_k127_5030728_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 617.0
TLS3_k127_5030728_6 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 301.0
TLS3_k127_5030728_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005901 266.0
TLS3_k127_5030728_8 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002346 274.0
TLS3_k127_5030728_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000001396 223.0
TLS3_k127_5035120_0 Putative RNA methylase family UPF0020 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 406.0
TLS3_k127_5035120_1 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 355.0
TLS3_k127_5035120_2 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000002235 226.0
TLS3_k127_503620_0 self proteolysis - - - 0.0 1693.0
TLS3_k127_503620_1 Asparagine synthase K01953 - 6.3.5.4 2.219e-214 700.0
TLS3_k127_503620_10 - - - - 0.00000000000007988 80.0
TLS3_k127_503620_11 histone H2A K63-linked ubiquitination - - - 0.000002371 57.0
TLS3_k127_503620_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 567.0
TLS3_k127_503620_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 391.0
TLS3_k127_503620_5 - - - - 0.00000000000000000000000000000000000000000000000002962 196.0
TLS3_k127_503620_6 Universal stress protein - - - 0.0000000000000000000000000000000000000001089 154.0
TLS3_k127_503620_9 Acyl carrier protein - - - 0.00000000000004585 81.0
TLS3_k127_5062087_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1122.0
TLS3_k127_5062087_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 6.457e-296 914.0
TLS3_k127_5062087_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 4.222e-206 655.0
TLS3_k127_5062087_3 alginic acid biosynthetic process K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 314.0
TLS3_k127_5062087_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002032 295.0
TLS3_k127_5062087_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000001375 160.0
TLS3_k127_5062087_6 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000003475 168.0
TLS3_k127_5062087_7 DNA-templated transcription, initiation - - - 0.000000000000000000000000846 112.0
TLS3_k127_5062956_0 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 604.0
TLS3_k127_5062956_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 620.0
TLS3_k127_5062956_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 467.0
TLS3_k127_5062956_4 Carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 415.0
TLS3_k127_5062956_5 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 350.0
TLS3_k127_5062956_6 Glutathione S-transferase, N-terminal domain K11208 - - 0.000000000000000000000000000000000000000000000000000000000005308 214.0
TLS3_k127_5062956_7 Cytochrome c - - - 0.000000000000000000000000003264 117.0
TLS3_k127_507005_0 Belongs to the K00958,K13811 - 2.7.1.25,2.7.7.4 1.008e-255 806.0
TLS3_k127_507005_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 569.0
TLS3_k127_507005_10 ThiS family K03636 - - 0.00000000000000000000000000000000000000004659 153.0
TLS3_k127_507005_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 539.0
TLS3_k127_507005_4 domain protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 299.0
TLS3_k127_507005_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 285.0
TLS3_k127_507005_6 alkyl hydroperoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005959 264.0
TLS3_k127_507005_7 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000008401 261.0
TLS3_k127_507005_8 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003826 266.0
TLS3_k127_508977_0 AMP-binding enzyme C-terminal domain K00666 - - 1.121e-292 906.0
TLS3_k127_508977_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 541.0
TLS3_k127_508977_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 418.0
TLS3_k127_508977_3 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008116 293.0
TLS3_k127_508977_5 Domain of unknown function (DUF4276) - - - 0.000000000000000000000000000000000000000000000000000002031 198.0
TLS3_k127_508977_7 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000001549 160.0
TLS3_k127_508977_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000006861 72.0
TLS3_k127_5096257_0 domain protein K21147 - 2.7.7.80,2.8.1.11 6.674e-220 687.0
TLS3_k127_5096257_2 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 313.0
TLS3_k127_5096257_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000001253 231.0
TLS3_k127_5096257_5 Cytochrome c - - - 0.00000000000006231 74.0
TLS3_k127_5115625_0 Tetratricopeptide repeat - - - 0.0 1643.0
TLS3_k127_5118993_0 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 595.0
TLS3_k127_5118993_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 516.0
TLS3_k127_5118993_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 460.0
TLS3_k127_5118993_3 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 297.0
TLS3_k127_5118993_6 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000003649 82.0
TLS3_k127_512670_0 Outer membrane protein beta-barrel family - - - 0.0 1086.0
TLS3_k127_512670_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1015.0
TLS3_k127_512670_10 copper resistance - - - 0.00000000005596 66.0
TLS3_k127_512670_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 6.269e-316 1009.0
TLS3_k127_512670_3 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 544.0
TLS3_k127_512670_4 TonB system transport protein ExbB TolQ K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 307.0
TLS3_k127_512670_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000000005153 222.0
TLS3_k127_512670_6 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000000000001794 186.0
TLS3_k127_512670_7 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000001224 175.0
TLS3_k127_512670_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000002642 135.0
TLS3_k127_512670_9 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000000000002413 121.0
TLS3_k127_5128810_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 2.787e-270 837.0
TLS3_k127_5128810_10 Response regulator, receiver K03413 - - 0.00000000000000000000001018 106.0
TLS3_k127_5128810_11 Molydopterin dinucleotide binding domain - - - 0.00000000007646 70.0
TLS3_k127_5128810_13 Bacterial regulatory proteins, tetR family - - - 0.0001409 46.0
TLS3_k127_5128810_2 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 377.0
TLS3_k127_5128810_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 359.0
TLS3_k127_5128810_4 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 300.0
TLS3_k127_5128810_5 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001341 282.0
TLS3_k127_5128810_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005771 246.0
TLS3_k127_5128810_7 cyclic nucleotide binding K01420,K10914,K21561,K22490 GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009314,GO:0009416,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019216,GO:0019219,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0042803,GO:0043565,GO:0045828,GO:0045834,GO:0045893,GO:0045935,GO:0046889,GO:0046890,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071214,GO:0071478,GO:0071482,GO:0080090,GO:0097159,GO:0104004,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1904143,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000001532 239.0
TLS3_k127_5128810_8 Lipase (class 3) K01046 - 3.1.1.3 0.0000000000000000000000000000000005976 150.0
TLS3_k127_5128810_9 Protein-disulfide isomerase - - - 0.000000000000000000000000001884 128.0
TLS3_k127_5206614_0 DEAD DEAH box K03724 - - 0.0 1957.0
TLS3_k127_5206614_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.381e-297 936.0
TLS3_k127_5206614_13 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000005675 74.0
TLS3_k127_5206614_14 Extensin-like protein C-terminus - - - 0.000000000003688 78.0
TLS3_k127_5206614_16 Protein of unknown function (DUF962) - - - 0.00000002378 64.0
TLS3_k127_5206614_17 Polyketide cyclase / dehydrase and lipid transport - - - 0.00003463 54.0
TLS3_k127_5206614_18 lipid binding K10779 - 3.6.4.12 0.0005454 52.0
TLS3_k127_5206614_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 402.0
TLS3_k127_5206614_3 Fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 376.0
TLS3_k127_5206614_4 Uncharacterized conserved protein (DUF2293) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 329.0
TLS3_k127_5206614_5 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 307.0
TLS3_k127_5206614_6 PA14 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 299.0
TLS3_k127_5206614_7 Anti-anti sigma factor protein K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002097 269.0
TLS3_k127_5206614_8 T5orf172 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006943 249.0
TLS3_k127_5206614_9 Belongs to the FPG family K05522 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000003671 243.0
TLS3_k127_5219706_0 Helicase K17675 - 3.6.4.13 0.0 1050.0
TLS3_k127_5219706_1 Multicopper oxidase K04753 - - 1.169e-215 679.0
TLS3_k127_5219706_10 Belongs to the cytochrome P450 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 343.0
TLS3_k127_5219706_11 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 308.0
TLS3_k127_5219706_12 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001665 277.0
TLS3_k127_5219706_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000126 292.0
TLS3_k127_5219706_14 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000002559 198.0
TLS3_k127_5219706_16 - - - - 0.00000000000000000000000000000000224 134.0
TLS3_k127_5219706_17 - - - - 0.000000000000000000000000000005554 122.0
TLS3_k127_5219706_18 - - - - 0.000000000000000000002129 102.0
TLS3_k127_5219706_2 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 1.55e-198 625.0
TLS3_k127_5219706_3 homogentisate 12-dioxygenase K00451 - 1.13.11.5 2.625e-195 634.0
TLS3_k127_5219706_4 short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 601.0
TLS3_k127_5219706_5 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 521.0
TLS3_k127_5219706_6 AAA domain (dynein-related subfamily) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 496.0
TLS3_k127_5219706_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 469.0
TLS3_k127_5219706_9 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 355.0
TLS3_k127_5229132_0 PFAM MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 630.0
TLS3_k127_5229132_1 organic phosphonate transport K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001127 254.0
TLS3_k127_5230970_0 Involved in the tonB-independent uptake of proteins - - - 1.169e-277 877.0
TLS3_k127_5230970_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 332.0
TLS3_k127_5230970_3 phosphoprotein phosphatase activity K07313 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 330.0
TLS3_k127_5230970_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001027 280.0
TLS3_k127_5230970_5 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001155 264.0
TLS3_k127_5230970_6 Peptidase family S49 K04773 - - 0.0000000000000009668 79.0
TLS3_k127_5232180_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 5.193e-291 914.0
TLS3_k127_5232180_1 Thioredoxin - - - 1.804e-219 700.0
TLS3_k127_5232180_10 of the major facilitator superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003376 274.0
TLS3_k127_5232180_11 Eco57I restriction-modification methylase - - - 0.00000000000000000000000000000000000000000000000000006303 209.0
TLS3_k127_5232180_13 double-stranded DNA endodeoxyribonuclease activity K02411 - - 0.00000000000000000000000000000000001301 141.0
TLS3_k127_5232180_2 HAMP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 584.0
TLS3_k127_5232180_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 582.0
TLS3_k127_5232180_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 462.0
TLS3_k127_5232180_5 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 342.0
TLS3_k127_5232180_6 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 337.0
TLS3_k127_5232180_7 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 332.0
TLS3_k127_5232180_8 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 306.0
TLS3_k127_5232180_9 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002947 264.0
TLS3_k127_5263984_0 Non-ribosomal peptide - - - 0.0 1737.0
TLS3_k127_5263984_2 PD-(D/E)XK nuclease superfamily K09124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 567.0
TLS3_k127_5263984_3 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 446.0
TLS3_k127_5263984_4 ATPases associated with a variety of cellular activities K07452 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 422.0
TLS3_k127_5263984_5 DNA/RNA non-specific endonuclease K01173 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 349.0
TLS3_k127_5263984_6 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002207 267.0
TLS3_k127_5263984_7 transcriptional regulator K18939 - - 0.000000000000000000000000000000000005277 145.0
TLS3_k127_5263984_8 Nuclease A inhibitor-like protein - - - 0.0000000000000000000000000003171 119.0
TLS3_k127_5263984_9 Transposase, Mutator family - - - 0.00002388 49.0
TLS3_k127_5280640_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 637.0
TLS3_k127_5280640_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 596.0
TLS3_k127_5280640_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001388 231.0
TLS3_k127_5280640_11 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000004449 236.0
TLS3_k127_5280640_12 - - - - 0.000000000000000000000000000000000000000000000000000000000001821 220.0
TLS3_k127_5280640_13 transferase activity, transferring glycosyl groups K00754 - - 0.000000000000000000000000000000000000000000001205 190.0
TLS3_k127_5280640_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000391 188.0
TLS3_k127_5280640_15 Nitroreductase family - - - 0.000000000000000000000000000000000008163 153.0
TLS3_k127_5280640_16 - - - - 0.000000000000000000000000000001072 130.0
TLS3_k127_5280640_19 CAAX protease self-immunity K07052 - - 0.00000000000001973 82.0
TLS3_k127_5280640_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 576.0
TLS3_k127_5280640_20 Outer membrane protein beta-barrel domain - - - 0.00000000000004304 83.0
TLS3_k127_5280640_21 Domain of unknown function (DUF4382) - - - 0.0000001228 61.0
TLS3_k127_5280640_22 Cell surface receptor IPT TIG - - - 0.000009377 60.0
TLS3_k127_5280640_24 Phosphotransferase enzyme family - - - 0.0005062 51.0
TLS3_k127_5280640_3 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 511.0
TLS3_k127_5280640_4 TfuA-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 421.0
TLS3_k127_5280640_5 YcaO cyclodehydratase, ATP-ad Mg2+-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 382.0
TLS3_k127_5280640_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 374.0
TLS3_k127_5280640_7 Membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 358.0
TLS3_k127_5280640_8 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006268 268.0
TLS3_k127_5280640_9 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001987 260.0
TLS3_k127_5283269_0 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 3.806e-290 909.0
TLS3_k127_5283269_1 PFAM Glycoside hydrolase 15-related K01178 - 3.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 439.0
TLS3_k127_5283269_2 transporter component K07112 - - 0.0000000000000000000000013 107.0
TLS3_k127_5283269_3 Transporter Component K07112 - - 0.0002045 45.0
TLS3_k127_5287507_0 cyclic-guanylate-specific phosphodiesterase activity K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 482.0
TLS3_k127_5287507_1 Protein of unknown function (DUF1592) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 380.0
TLS3_k127_5287507_3 guanyl-nucleotide exchange factor activity K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000002804 239.0
TLS3_k127_5287507_5 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000001316 191.0
TLS3_k127_5287507_7 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000001785 140.0
TLS3_k127_5303019_0 WD-40 repeat - - - 3.97e-308 968.0
TLS3_k127_5303019_1 Flavin containing amine oxidoreductase - - - 1.869e-275 853.0
TLS3_k127_5303019_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 359.0
TLS3_k127_5303019_11 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 343.0
TLS3_k127_5303019_12 Acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 347.0
TLS3_k127_5303019_13 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 324.0
TLS3_k127_5303019_14 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 327.0
TLS3_k127_5303019_15 Leucine-rich repeat (LRR) protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006279 265.0
TLS3_k127_5303019_16 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000004031 231.0
TLS3_k127_5303019_17 Cyclic nucleotide-monophosphate binding domain K07001 - - 0.0000000000000000000000000000000000000000000000006631 194.0
TLS3_k127_5303019_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.435e-254 796.0
TLS3_k127_5303019_3 AAA ATPase domain - - - 2.386e-242 794.0
TLS3_k127_5303019_4 Protease prsW family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 488.0
TLS3_k127_5303019_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 492.0
TLS3_k127_5303019_7 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 404.0
TLS3_k127_5303019_8 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 426.0
TLS3_k127_5303019_9 metal cluster binding K18475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 383.0
TLS3_k127_5306407_0 DEAD-like helicases superfamily K07012 - - 7.374e-280 879.0
TLS3_k127_5306407_1 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 361.0
TLS3_k127_5306407_2 CRISPR-associated protein (Cas_Cas5) K19119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 312.0
TLS3_k127_5324710_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 2.513e-251 799.0
TLS3_k127_5324710_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 416.0
TLS3_k127_5324710_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000000000005224 241.0
TLS3_k127_5332874_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K06147,K06148,K18889,K18893 - - 4.856e-206 661.0
TLS3_k127_5332874_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 424.0
TLS3_k127_5332874_2 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005998 285.0
TLS3_k127_5332874_3 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.000000000000000000000000000000000000000000000000000000000000000000006261 250.0
TLS3_k127_5332874_4 DTW - - - 0.00000000000000000000000000000000000000002445 163.0
TLS3_k127_5332874_7 Acetyltransferase (GNAT) domain - - - 0.00000000007375 70.0
TLS3_k127_53508_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001951 297.0
TLS3_k127_53508_1 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000001081 225.0
TLS3_k127_53508_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000001097 236.0
TLS3_k127_535657_0 ABC1 family - - - 1.992e-275 873.0
TLS3_k127_535657_11 PFAM Patatin - - - 0.0000000000000000000000000000000000000003727 167.0
TLS3_k127_535657_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000008806 121.0
TLS3_k127_535657_13 - - - - 0.0000000000000000000001266 107.0
TLS3_k127_535657_2 COG2755 Lysophospholipase L1 and related esterases - - - 1.077e-216 682.0
TLS3_k127_535657_3 Type II secretion system (T2SS), protein F K02653 - - 6.101e-210 657.0
TLS3_k127_535657_4 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 551.0
TLS3_k127_535657_5 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000737 527.0
TLS3_k127_535657_6 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 470.0
TLS3_k127_535657_7 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 425.0
TLS3_k127_535657_8 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 285.0
TLS3_k127_535657_9 heme binding - - - 0.000000000000000000000000000000000000000000000000000000000002265 219.0
TLS3_k127_5370993_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 1.17e-281 884.0
TLS3_k127_5370993_1 Voltage gated chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 547.0
TLS3_k127_5370993_10 - - - - 0.0000000000000000004688 92.0
TLS3_k127_5370993_12 AAA domain - - - 0.0000000000001888 71.0
TLS3_k127_5370993_13 PFAM conserved - - - 0.000000000009469 71.0
TLS3_k127_5370993_2 PFAM Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 404.0
TLS3_k127_5370993_3 COG0471 Di- and tricarboxylate K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 409.0
TLS3_k127_5370993_4 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 319.0
TLS3_k127_5370993_6 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000003664 220.0
TLS3_k127_5370993_7 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000005015 171.0
TLS3_k127_5370993_8 Membrane - - - 0.0000000000000000000000004841 109.0
TLS3_k127_5370993_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000003771 108.0
TLS3_k127_5372187_0 AAA ATPase domain - - - 0.0 1585.0
TLS3_k127_5372187_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0 1036.0
TLS3_k127_5372187_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 425.0
TLS3_k127_5372187_11 PFAM Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001936 291.0
TLS3_k127_5372187_12 related to nicotinamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005611 273.0
TLS3_k127_5372187_13 transcription factor binding K07315,K17763 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000004029 235.0
TLS3_k127_5372187_14 PFAM helix-turn-helix, AraC type ThiJ PfpI - - - 0.000000000000000000000000000000000000000000000000001443 184.0
TLS3_k127_5372187_15 D-arabinono-1,4-lactone oxidase - - - 0.0000000000000000000000000000000000000000000003862 191.0
TLS3_k127_5372187_16 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000001196 153.0
TLS3_k127_5372187_17 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000002929 144.0
TLS3_k127_5372187_18 guanyl-nucleotide exchange factor activity K02034 - - 0.00000000000000000000000000001235 138.0
TLS3_k127_5372187_19 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD) K11530 GO:0002952,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016853,GO:0044424,GO:0044444,GO:0044464,GO:0055114 5.3.1.32 0.000000000000000000006908 104.0
TLS3_k127_5372187_2 oxidoreductase activity K07114 - - 9.568e-311 973.0
TLS3_k127_5372187_20 PFAM response regulator receiver - - - 0.0000000000000000009142 90.0
TLS3_k127_5372187_21 von Willebrand factor (vWF) type A domain - GO:0006810,GO:0006897,GO:0006909,GO:0008150,GO:0016192,GO:0051179,GO:0051234,GO:0098657 - 0.000000001247 72.0
TLS3_k127_5372187_23 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000009611 60.0
TLS3_k127_5372187_3 Peptidase family M49 K01277 - 3.4.14.4 1.803e-290 925.0
TLS3_k127_5372187_4 Type II restriction enzyme, methylase subunits - - - 7.973e-279 874.0
TLS3_k127_5372187_5 FIST N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 476.0
TLS3_k127_5372187_6 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 494.0
TLS3_k127_5372187_7 PAS domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 441.0
TLS3_k127_5372187_8 dextransucrase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 413.0
TLS3_k127_5372187_9 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 423.0
TLS3_k127_5378336_0 Tetratricopeptide repeat - - - 0.0 2074.0
TLS3_k127_5378336_1 Tetratricopeptide repeat - - - 0.0 1182.0
TLS3_k127_5378336_13 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 352.0
TLS3_k127_5378336_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 341.0
TLS3_k127_5378336_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 312.0
TLS3_k127_5378336_16 Sugar (and other) transporter K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001123 285.0
TLS3_k127_5378336_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003273 269.0
TLS3_k127_5378336_19 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007525 273.0
TLS3_k127_5378336_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.18e-307 966.0
TLS3_k127_5378336_20 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000479 254.0
TLS3_k127_5378336_21 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000006949 214.0
TLS3_k127_5378336_22 PilZ domain - - - 0.0000000000000000000000000000000000000000000002407 170.0
TLS3_k127_5378336_23 Uncharacterised BCR, YnfA/UPF0060 family K09771 - - 0.0000000000000000000000000000000000000000001666 162.0
TLS3_k127_5378336_24 WxcM-like, C-terminal - - - 0.000000000000000000000000000000000000000005563 170.0
TLS3_k127_5378336_27 protein kinase activity - - - 0.00000000000000001196 85.0
TLS3_k127_5378336_29 Polysaccharide biosynthesis protein K03328 - - 0.0000000000001679 83.0
TLS3_k127_5378336_3 Zinc metalloprotease (Elastase) - - - 5.874e-245 786.0
TLS3_k127_5378336_30 Sugar (and other) transporter K07552 - - 0.0000000000009463 78.0
TLS3_k127_5378336_32 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000004571 63.0
TLS3_k127_5378336_33 nucleic acid-binding protein contains PIN domain K18828 - - 0.0000007005 54.0
TLS3_k127_5378336_34 Glycosyltransferase like family 2 - - - 0.00001096 58.0
TLS3_k127_5378336_4 L,D-transpeptidase catalytic domain - - - 1.678e-226 719.0
TLS3_k127_5378336_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 1.333e-215 679.0
TLS3_k127_5378336_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 589.0
TLS3_k127_5378336_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 576.0
TLS3_k127_5378336_8 Belongs to the DegT DnrJ EryC1 family K13310,K16436 - 2.6.1.106 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 490.0
TLS3_k127_5378336_9 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 479.0
TLS3_k127_5391020_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 4.886e-215 689.0
TLS3_k127_5391020_1 GAF domain - - - 2.149e-199 636.0
TLS3_k127_5391020_10 methyltransferase - - - 0.000000000000000000000000000000003338 133.0
TLS3_k127_5391020_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 511.0
TLS3_k127_5391020_3 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 433.0
TLS3_k127_5391020_4 High confidence in function and specificity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 349.0
TLS3_k127_5391020_5 double-stranded DNA endodeoxyribonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 291.0
TLS3_k127_5391020_6 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001513 298.0
TLS3_k127_5391020_7 double-stranded DNA endodeoxyribonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000004713 219.0
TLS3_k127_5391020_8 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000002472 145.0
TLS3_k127_5391020_9 Peptidase family M13 K07386 - - 0.000000000000000000000000000000000003559 153.0
TLS3_k127_5413839_0 Peptidase family M1 domain - - - 9.099e-207 656.0
TLS3_k127_5413839_1 heat shock protein 70 K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 389.0
TLS3_k127_5413839_2 - - - - 0.000000000000000000000000000006084 135.0
TLS3_k127_545692_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 425.0
TLS3_k127_545692_1 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000899 218.0
TLS3_k127_545692_2 Fic/DOC family K07341 - - 0.000000000000000000000000000000000000003659 152.0
TLS3_k127_545692_3 Belongs to the FtsK SpoIIIE SftA family K03466,K07474,K19175 - - 0.00000000001422 70.0
TLS3_k127_545692_4 PFAM SpoVT AbrB K07172,K18842 - - 0.0001108 53.0
TLS3_k127_5477183_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 4.22e-269 843.0
TLS3_k127_5477183_2 alcohol dehydrogenase K18012 - 1.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 541.0
TLS3_k127_5477183_3 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 460.0
TLS3_k127_5478784_0 kinase activity K01007 - 2.7.9.2 0.0 1236.0
TLS3_k127_5478784_1 Heat shock 70 kDa protein K04043 - - 0.0 1097.0
TLS3_k127_5478784_10 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000001203 123.0
TLS3_k127_5478784_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 570.0
TLS3_k127_5478784_3 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 483.0
TLS3_k127_5478784_4 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 482.0
TLS3_k127_5478784_5 TIGRFAM geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 364.0
TLS3_k127_5478784_6 pseudouridine synthase activity K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000103 301.0
TLS3_k127_5478784_8 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000007222 173.0
TLS3_k127_5485504_0 Family membership K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 309.0
TLS3_k127_5485504_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002618 280.0
TLS3_k127_5485504_2 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005293 270.0
TLS3_k127_5485504_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000241 151.0
TLS3_k127_5485504_4 Domain of unknown function (DUF4276) - - - 0.0000000000000000000006059 105.0
TLS3_k127_5492757_0 unfolded protein binding K04079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 618.0
TLS3_k127_5492757_2 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 463.0
TLS3_k127_5492757_3 MATE efflux family protein K03327 - - 0.00000000000000000000000000000000000000000000001148 189.0
TLS3_k127_5492757_4 PFAM Purine catabolism regulatory protein-like family K09684 - - 0.00000000000000000000000000000000000000003992 168.0
TLS3_k127_5492757_5 STAS domain K17763 - - 0.000000000000000000000000008987 124.0
TLS3_k127_5492757_6 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000198 111.0
TLS3_k127_5492757_7 oxidoreductase activity K07114 - - 0.00000000000000000001134 106.0
TLS3_k127_5492757_8 - - - - 0.0007318 42.0
TLS3_k127_5507414_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 2.753e-306 951.0
TLS3_k127_5507414_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.395e-221 693.0
TLS3_k127_5507414_11 Uncharacterised nucleotidyltransferase - - - 0.000000001522 68.0
TLS3_k127_5507414_2 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 293.0
TLS3_k127_5507414_3 MerR, DNA binding K19591 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004755 246.0
TLS3_k127_5507414_4 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000002017 237.0
TLS3_k127_5507414_5 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000000000000000000000006419 234.0
TLS3_k127_5507414_6 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000000000000004476 213.0
TLS3_k127_5507414_7 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000000000000000002507 205.0
TLS3_k127_5507414_8 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000002421 163.0
TLS3_k127_5507414_9 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013,K16014 - - 0.0000000000000000000000000000000006694 149.0
TLS3_k127_5509830_1 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 470.0
TLS3_k127_5509830_10 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000001107 200.0
TLS3_k127_5509830_11 Belongs to the peptidase M12A family - - - 0.000000000000000000000000000000000000001057 154.0
TLS3_k127_5509830_14 Annexin repeats K17095 - - 0.0009282 52.0
TLS3_k127_5509830_2 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 450.0
TLS3_k127_5509830_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 424.0
TLS3_k127_5509830_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 374.0
TLS3_k127_5509830_5 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 339.0
TLS3_k127_5509830_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000497 274.0
TLS3_k127_5509830_7 antisigma factor binding - - - 0.00000000000000000000000000000000000000000000000000000000000000001759 236.0
TLS3_k127_5509830_9 protein domain, possibly involved in tellurite resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000192 221.0
TLS3_k127_5517992_0 Flavin containing amine oxidoreductase - - - 7.513e-228 716.0
TLS3_k127_5517992_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 456.0
TLS3_k127_5517992_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 367.0
TLS3_k127_5517992_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000007492 228.0
TLS3_k127_5517992_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000812 188.0
TLS3_k127_5517992_5 Histidine kinase - - - 0.000000000000000000000000000000000000002855 164.0
TLS3_k127_5517992_6 Ricin-type beta-trefoil lectin domain - - - 0.00000001907 68.0
TLS3_k127_5522907_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 1.274e-211 664.0
TLS3_k127_5522907_10 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001365 274.0
TLS3_k127_5522907_13 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000006361 48.0
TLS3_k127_5522907_3 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 424.0
TLS3_k127_5522907_4 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 392.0
TLS3_k127_5522907_5 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 392.0
TLS3_k127_5522907_6 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 340.0
TLS3_k127_5522907_7 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 330.0
TLS3_k127_5522907_8 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 301.0
TLS3_k127_5522907_9 tRNA wobble cytosine modification - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 297.0
TLS3_k127_5533083_0 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000001866 247.0
TLS3_k127_5533083_1 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000006023 175.0
TLS3_k127_5533083_3 ATPase activity K01990 - - 0.00000002292 67.0
TLS3_k127_5546847_0 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 580.0
TLS3_k127_5546847_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 578.0
TLS3_k127_5546847_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 328.0
TLS3_k127_5546847_3 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 287.0
TLS3_k127_5546847_4 domain, Protein - - - 0.000000000000000000000000000000000000000000000002278 189.0
TLS3_k127_5546847_5 Thioesterase superfamily - - - 0.0000000000000000002219 89.0
TLS3_k127_5559019_0 glutaminyl-tRNA K01886 - 6.1.1.18 0.0 1055.0
TLS3_k127_5559019_1 DUF1704 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 577.0
TLS3_k127_5559019_2 Domain of unknown function (DUF4215) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 578.0
TLS3_k127_5559019_3 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000001648 214.0
TLS3_k127_5559019_4 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000007553 180.0
TLS3_k127_5559019_5 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000001346 126.0
TLS3_k127_5572745_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 573.0
TLS3_k127_5572745_1 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 518.0
TLS3_k127_5572745_2 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 462.0
TLS3_k127_5572745_4 PFAM DHH family - - - 0.00000000000000000000000000000000000000000000000000000000000001745 229.0
TLS3_k127_5584549_0 RHS Repeat - - - 0.0 1201.0
TLS3_k127_5584549_1 Rhs family - - - 0.0 1132.0
TLS3_k127_5584549_10 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 452.0
TLS3_k127_5584549_11 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 428.0
TLS3_k127_5584549_12 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K03921 - 1.14.19.11,1.14.19.2,1.14.19.26,1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 381.0
TLS3_k127_5584549_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 312.0
TLS3_k127_5584549_14 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001436 297.0
TLS3_k127_5584549_16 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000001607 243.0
TLS3_k127_5584549_17 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000005238 192.0
TLS3_k127_5584549_18 Methyltransferase small domain K15460 - 2.1.1.223 0.0000000000000000000000000000000000000000000001192 192.0
TLS3_k127_5584549_19 - - - - 0.000000000000000000000000000000000000006905 158.0
TLS3_k127_5584549_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0 1034.0
TLS3_k127_5584549_20 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000005313 143.0
TLS3_k127_5584549_21 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000003172 102.0
TLS3_k127_5584549_22 Immunity protein 26 - - - 0.0000000000001439 80.0
TLS3_k127_5584549_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 7.874e-247 767.0
TLS3_k127_5584549_4 Rod shape-determining protein K03569 - - 1.669e-212 664.0
TLS3_k127_5584549_5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 7.645e-201 643.0
TLS3_k127_5584549_6 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 589.0
TLS3_k127_5584549_7 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 550.0
TLS3_k127_5584549_8 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 452.0
TLS3_k127_5584549_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 464.0
TLS3_k127_5597401_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 569.0
TLS3_k127_5597401_1 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 387.0
TLS3_k127_5597401_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000001093 192.0
TLS3_k127_5626790_0 - - - - 3.436e-202 678.0
TLS3_k127_5626790_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 547.0
TLS3_k127_5626790_10 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001511 267.0
TLS3_k127_5626790_11 - - - - 0.0000000000000000000000000005665 113.0
TLS3_k127_5626790_2 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 549.0
TLS3_k127_5626790_3 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 518.0
TLS3_k127_5626790_4 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 424.0
TLS3_k127_5626790_5 transmembrane transport K03442,K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 428.0
TLS3_k127_5626790_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 392.0
TLS3_k127_5626790_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 392.0
TLS3_k127_5626790_8 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 396.0
TLS3_k127_5626790_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 306.0
TLS3_k127_5635649_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 301.0
TLS3_k127_5635649_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000001705 238.0
TLS3_k127_5635649_4 COG3568 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000002539 169.0
TLS3_k127_5635649_5 Acyltransferase - - - 0.0000000000000000000000000000000000000002763 160.0
TLS3_k127_5635649_6 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000000000000008978 119.0
TLS3_k127_5635649_7 - - - - 0.000000000001661 74.0
TLS3_k127_5635649_9 Pfam matches to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1 K07126 - - 0.0005723 46.0
TLS3_k127_5643172_0 Belongs to the glycosyl hydrolase 35 family K12308 - 3.2.1.23 6.4e-323 1001.0
TLS3_k127_5643172_1 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 567.0
TLS3_k127_5643172_2 - - - - 0.000000000000000000000000000000000000000000000000004935 183.0
TLS3_k127_5643172_3 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000002061 86.0
TLS3_k127_5651745_0 ABC transporter K15738 - - 7.561e-273 853.0
TLS3_k127_5651745_2 - - - - 0.00000000000000000000000000000000001532 154.0
TLS3_k127_5663184_0 arylsulfatase activity K07014 - - 1.819e-273 861.0
TLS3_k127_5663184_1 Bacterial protein of unknown function (DUF885) - - - 5.168e-231 732.0
TLS3_k127_5663184_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.13e-213 669.0
TLS3_k127_5663184_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 599.0
TLS3_k127_5663184_4 - - - - 0.000000000000000000000000000000000000000000000000000000001234 207.0
TLS3_k127_5663184_5 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000001184 205.0
TLS3_k127_5663184_7 - - - - 0.00000000001387 72.0
TLS3_k127_5663184_9 Archaeal Type IV pilin, N-terminal - - - 0.0007644 53.0
TLS3_k127_5678568_0 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 517.0
TLS3_k127_5678568_1 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 483.0
TLS3_k127_5678568_2 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 370.0
TLS3_k127_5678568_3 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 331.0
TLS3_k127_5678568_5 transcriptional regulator K03892 - - 0.000000000000000000000000002578 115.0
TLS3_k127_5678788_0 Belongs to the cytochrome P450 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 392.0
TLS3_k127_5678788_1 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 316.0
TLS3_k127_5678788_2 Prenyltransferase and squalene oxidase repeat K06045,K18115 - 4.2.1.129,4.2.1.137,5.4.99.17 0.000000000000000000000000000000000000000000000000000000000000003479 237.0
TLS3_k127_5678788_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000003744 195.0
TLS3_k127_5678788_4 HD superfamily hydrolase involved in NAD metabolism - - - 0.0000000000000000000000000000000000000000000001859 174.0
TLS3_k127_5678788_5 - - - - 0.0000000000000000000000000000000000000004298 159.0
TLS3_k127_5678788_6 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000002202 135.0
TLS3_k127_5678788_7 - - - - 0.00000001552 59.0
TLS3_k127_5678788_8 protein kinase activity K12132 - 2.7.11.1 0.0000008616 54.0
TLS3_k127_5683951_0 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0 1651.0
TLS3_k127_5683951_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 6.926e-306 972.0
TLS3_k127_5683951_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 524.0
TLS3_k127_5683951_3 - - - - 0.000000000000000000000000000002728 133.0
TLS3_k127_5683951_4 - - - - 0.0000000000000000000000000004748 126.0
TLS3_k127_5683951_5 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000007243 84.0
TLS3_k127_5683951_6 Phage integrase family - - - 0.00000001112 60.0
TLS3_k127_569312_0 Putative diguanylate phosphodiesterase - - - 5.218e-207 659.0
TLS3_k127_569312_1 Bacterial extracellular solute-binding protein K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 617.0
TLS3_k127_569312_10 - - - - 0.0000000000005886 72.0
TLS3_k127_569312_11 - - - - 0.00000003194 64.0
TLS3_k127_569312_2 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 571.0
TLS3_k127_569312_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 490.0
TLS3_k127_569312_4 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 480.0
TLS3_k127_569312_5 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 343.0
TLS3_k127_569312_6 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000004135 270.0
TLS3_k127_569312_7 Glyoxalase-like domain K07032 - - 0.000000000000000000000000000000000000000000000000000000000000005984 221.0
TLS3_k127_569312_9 Domain of unknown function (DUF4920) - - - 0.0000000000000000000000000000000000000000001164 166.0
TLS3_k127_5696257_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 5.878e-266 832.0
TLS3_k127_5696257_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 593.0
TLS3_k127_5696257_11 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000001271 262.0
TLS3_k127_5696257_12 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000001339 239.0
TLS3_k127_5696257_13 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000003725 202.0
TLS3_k127_5696257_14 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000001758 177.0
TLS3_k127_5696257_16 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000001106 158.0
TLS3_k127_5696257_17 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000002448 132.0
TLS3_k127_5696257_19 Nuclease A inhibitor-like protein - - - 0.000001263 58.0
TLS3_k127_5696257_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 519.0
TLS3_k127_5696257_20 NHL repeat - - - 0.000001518 61.0
TLS3_k127_5696257_3 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 469.0
TLS3_k127_5696257_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 438.0
TLS3_k127_5696257_5 HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 357.0
TLS3_k127_5696257_6 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 332.0
TLS3_k127_5696257_8 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 322.0
TLS3_k127_5696257_9 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 304.0
TLS3_k127_5703950_0 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 2.878e-306 955.0
TLS3_k127_5703950_1 Histidine ammonia-lyase K01745 - 4.3.1.3 5.526e-244 762.0
TLS3_k127_5703950_10 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000002755 239.0
TLS3_k127_5703950_12 peptidyl-prolyl cis-trans isomerase activity K01802,K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000002755 179.0
TLS3_k127_5703950_13 Biotin-requiring enzyme - - - 0.000000000000000000000000000000000000000000000002968 177.0
TLS3_k127_5703950_15 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000002326 87.0
TLS3_k127_5703950_17 bacterial-type flagellum organization K02411 - - 0.000000001953 63.0
TLS3_k127_5703950_18 Nacht domain - - - 0.0000008334 55.0
TLS3_k127_5703950_2 protein containing a von Willebrand factor type A (vWA) domain - - - 6.147e-237 741.0
TLS3_k127_5703950_4 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 470.0
TLS3_k127_5703950_5 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 362.0
TLS3_k127_5703950_6 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 326.0
TLS3_k127_5703950_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004587 284.0
TLS3_k127_5703950_8 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002465 281.0
TLS3_k127_570916_0 protein conserved in bacteria K11904 - - 7.51e-255 806.0
TLS3_k127_570916_1 Amino acid permease - - - 7.462e-248 781.0
TLS3_k127_570916_10 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 433.0
TLS3_k127_570916_11 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 438.0
TLS3_k127_570916_12 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 405.0
TLS3_k127_570916_13 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 398.0
TLS3_k127_570916_14 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 375.0
TLS3_k127_570916_15 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 359.0
TLS3_k127_570916_16 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 335.0
TLS3_k127_570916_17 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 342.0
TLS3_k127_570916_18 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 296.0
TLS3_k127_570916_19 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003814 273.0
TLS3_k127_570916_2 M18 family aminopeptidase K01267 - 3.4.11.21 2.278e-202 642.0
TLS3_k127_570916_20 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001186 239.0
TLS3_k127_570916_21 Domain of unknown function (DUF4150) - - - 0.000000000000000000000000000000000000000000001214 170.0
TLS3_k127_570916_22 General stress protein K06884 - - 0.00000000000000000000000000000000000000000006792 171.0
TLS3_k127_570916_23 synthase K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000002619 174.0
TLS3_k127_570916_26 Zinc finger domain K04043 - - 0.0000755 52.0
TLS3_k127_570916_27 - - - - 0.0007606 53.0
TLS3_k127_570916_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 586.0
TLS3_k127_570916_4 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 574.0
TLS3_k127_570916_5 fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 546.0
TLS3_k127_570916_6 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 576.0
TLS3_k127_570916_7 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 511.0
TLS3_k127_570916_8 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 510.0
TLS3_k127_570916_9 Phenylacetate-CoA oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 453.0
TLS3_k127_5710362_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000007082 217.0
TLS3_k127_5710362_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000001449 186.0
TLS3_k127_5710362_2 repeat protein - - - 0.00002302 54.0
TLS3_k127_5721122_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 1.543e-288 908.0
TLS3_k127_5721122_1 NLP P60 protein - - - 3.256e-210 674.0
TLS3_k127_5721122_10 Cupredoxin-like domain - - - 0.00000000000000000000000004929 119.0
TLS3_k127_5721122_11 conserved small protein - - - 0.00000000000000000000005718 112.0
TLS3_k127_5721122_12 Patatin-like phospholipase K06900 - - 0.00000000000003681 85.0
TLS3_k127_5721122_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 522.0
TLS3_k127_5721122_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 525.0
TLS3_k127_5721122_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 344.0
TLS3_k127_5721122_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 310.0
TLS3_k127_5721122_6 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002323 268.0
TLS3_k127_5721122_7 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000004087 249.0
TLS3_k127_5721122_8 - - - - 0.000000000000000000000000000000000001741 152.0
TLS3_k127_5721122_9 Rhomboid family - - - 0.0000000000000000000000000001842 128.0
TLS3_k127_5753423_0 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 2.897e-220 692.0
TLS3_k127_5753423_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 563.0
TLS3_k127_5753423_10 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000007209 250.0
TLS3_k127_5753423_11 ATP-NAD kinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000002486 246.0
TLS3_k127_5753423_13 Zn-ribbon-containing protein involved in phosphonate metabolism K06193 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000003379 177.0
TLS3_k127_5753423_14 AntiSigma factor - - - 0.000000000000000000000000000000000000000000338 167.0
TLS3_k127_5753423_15 Domain of unknown function (DUF1844) - - - 0.000000000000000000000000000000000009045 141.0
TLS3_k127_5753423_16 Peptidase family M23 - - - 0.00000000000000000000000000000009712 135.0
TLS3_k127_5753423_17 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000002616 105.0
TLS3_k127_5753423_19 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.000000000000000002214 99.0
TLS3_k127_5753423_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 560.0
TLS3_k127_5753423_21 - - - - 0.00008055 49.0
TLS3_k127_5753423_3 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 539.0
TLS3_k127_5753423_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 513.0
TLS3_k127_5753423_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 493.0
TLS3_k127_5753423_6 desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 470.0
TLS3_k127_5753423_7 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 440.0
TLS3_k127_5753423_8 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 397.0
TLS3_k127_5753423_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 370.0
TLS3_k127_5761716_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 605.0
TLS3_k127_5761716_10 high-affinity sulfate:proton symporter activity K06203 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000001543 233.0
TLS3_k127_5761716_11 protein contain chitin-binding domain type 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000396 241.0
TLS3_k127_5761716_12 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000002961 189.0
TLS3_k127_5761716_13 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000000002587 156.0
TLS3_k127_5761716_15 DNA integration - - - 0.00000000000000000000000000002134 130.0
TLS3_k127_5761716_16 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000001828 127.0
TLS3_k127_5761716_17 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.000000000000000000000001013 121.0
TLS3_k127_5761716_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 595.0
TLS3_k127_5761716_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 548.0
TLS3_k127_5761716_4 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 536.0
TLS3_k127_5761716_5 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 434.0
TLS3_k127_5761716_6 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 430.0
TLS3_k127_5761716_7 belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 344.0
TLS3_k127_5761716_9 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 281.0
TLS3_k127_5766379_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 521.0
TLS3_k127_5766379_1 Protein of unknown function (DUF1348) K09958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 295.0
TLS3_k127_5766379_4 - - - - 0.0000000001491 69.0
TLS3_k127_5766379_5 alcohol dehydrogenase - - - 0.0004132 44.0
TLS3_k127_577308_0 protein kinase activity - - - 0.0 1013.0
TLS3_k127_577308_1 Participates in both transcription termination and antitermination K02600 - - 1.18e-317 976.0
TLS3_k127_577308_10 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 504.0
TLS3_k127_577308_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 485.0
TLS3_k127_577308_12 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 456.0
TLS3_k127_577308_13 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 434.0
TLS3_k127_577308_14 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 403.0
TLS3_k127_577308_15 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 396.0
TLS3_k127_577308_16 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 401.0
TLS3_k127_577308_17 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 394.0
TLS3_k127_577308_18 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 360.0
TLS3_k127_577308_19 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 349.0
TLS3_k127_577308_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.66e-315 996.0
TLS3_k127_577308_20 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 336.0
TLS3_k127_577308_22 serine-type endopeptidase activity K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 318.0
TLS3_k127_577308_23 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 331.0
TLS3_k127_577308_25 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 291.0
TLS3_k127_577308_26 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008917 281.0
TLS3_k127_577308_27 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000000000000000000000000000000000000004071 238.0
TLS3_k127_577308_28 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000003341 222.0
TLS3_k127_577308_29 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000002689 231.0
TLS3_k127_577308_31 YjbR - - - 0.0000000000000000000000000000000000000002417 159.0
TLS3_k127_577308_32 - - - - 0.00000000000000000000000000001484 129.0
TLS3_k127_577308_33 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000002241 122.0
TLS3_k127_577308_35 Response regulator, receiver - - - 0.00000000000000000001711 106.0
TLS3_k127_577308_36 amine dehydrogenase activity - - - 0.000000000000005041 90.0
TLS3_k127_577308_37 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000004962 72.0
TLS3_k127_577308_38 Type I restriction-modification system methyltransferase subunit K03427 - 2.1.1.72 0.000000000005718 66.0
TLS3_k127_577308_39 site-specific DNA-methyltransferase (adenine-specific) activity K03427 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.72 0.000000006504 67.0
TLS3_k127_577308_4 Protein conserved in bacteria - - - 1.031e-250 797.0
TLS3_k127_577308_40 HsdM N-terminal domain K03427 - 2.1.1.72 0.000002636 53.0
TLS3_k127_577308_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.072e-241 754.0
TLS3_k127_577308_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 4.733e-199 630.0
TLS3_k127_577308_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 8.271e-195 625.0
TLS3_k127_577308_8 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 519.0
TLS3_k127_577308_9 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 508.0
TLS3_k127_5774288_0 ErfK ybiS ycfS ynhG family protein - - - 3.638e-203 650.0
TLS3_k127_5774288_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 480.0
TLS3_k127_5774288_2 Histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 370.0
TLS3_k127_5774288_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 320.0
TLS3_k127_5774288_4 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000001069 235.0
TLS3_k127_5774288_5 Bacterial regulatory protein, Fis family K15012 - - 0.00000000000000000000000000000000000000000000000000000000000006637 237.0
TLS3_k127_5775179_0 4Fe-4S dicluster domain K17723 - 1.3.1.1 3.224e-269 831.0
TLS3_k127_5775179_1 Amidohydrolase family K01464 - 3.5.2.2 5.931e-266 822.0
TLS3_k127_5775179_11 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000003467 151.0
TLS3_k127_5775179_12 TPR repeat - - - 0.00000342 54.0
TLS3_k127_5775179_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 4.349e-251 796.0
TLS3_k127_5775179_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 3.341e-195 640.0
TLS3_k127_5775179_4 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 564.0
TLS3_k127_5775179_5 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 443.0
TLS3_k127_5775179_6 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009885 387.0
TLS3_k127_5775179_7 Family membership - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 298.0
TLS3_k127_5775179_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000002737 234.0
TLS3_k127_5775179_9 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000000000000000000007492 228.0
TLS3_k127_5776401_0 penicillin-binding protein K03587 - 3.4.16.4 0.0 1101.0
TLS3_k127_5776401_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.101e-274 847.0
TLS3_k127_5776401_10 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 369.0
TLS3_k127_5776401_11 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 343.0
TLS3_k127_5776401_12 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001299 269.0
TLS3_k127_5776401_14 SMART phosphoesterase PHP domain protein - - - 0.00000000000000001318 94.0
TLS3_k127_5776401_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.331e-221 691.0
TLS3_k127_5776401_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 3.036e-213 677.0
TLS3_k127_5776401_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.054e-210 671.0
TLS3_k127_5776401_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 623.0
TLS3_k127_5776401_6 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 588.0
TLS3_k127_5776401_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 457.0
TLS3_k127_5776401_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 442.0
TLS3_k127_5776401_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 374.0
TLS3_k127_5778464_0 Non-ribosomal peptide synthetase modules and related - - - 0.0 1418.0
TLS3_k127_5798827_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 K04041 - 3.1.3.11 2.061e-264 826.0
TLS3_k127_5798827_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 426.0
TLS3_k127_5798827_4 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000000000009704 178.0
TLS3_k127_5804813_0 TonB dependent receptor - - - 0.0 1124.0
TLS3_k127_5804813_1 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 405.0
TLS3_k127_5804813_10 COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit - - - 0.000000000000000000009422 103.0
TLS3_k127_5804813_11 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) - - - 0.00000000000003522 86.0
TLS3_k127_5804813_2 Protein of unknown function (DUF455) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 351.0
TLS3_k127_5804813_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 302.0
TLS3_k127_5804813_4 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003559 269.0
TLS3_k127_5804813_5 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000002321 219.0
TLS3_k127_5804813_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000005926 206.0
TLS3_k127_5804813_7 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000004912 167.0
TLS3_k127_5804813_8 Biopolymer transport protein K03559,K03560 - - 0.00000000000000000000000000000000000000004963 156.0
TLS3_k127_5804813_9 - - - - 0.00000000000000000000000000002363 131.0
TLS3_k127_5858895_0 TonB dependent receptor K02014 - - 3.273e-272 850.0
TLS3_k127_5858895_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.889e-232 734.0
TLS3_k127_5858895_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 511.0
TLS3_k127_5858895_3 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 471.0
TLS3_k127_5858895_4 PFAM amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 430.0
TLS3_k127_5858895_5 acetylesterase activity K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 373.0
TLS3_k127_5858895_6 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 377.0
TLS3_k127_5858895_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000155 219.0
TLS3_k127_5860428_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1443.0
TLS3_k127_5860428_1 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.96e-209 661.0
TLS3_k127_5860428_10 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000642 210.0
TLS3_k127_5860428_11 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000003194 200.0
TLS3_k127_5860428_12 - - - - 0.00000000000000000000000000000000000000000000004395 194.0
TLS3_k127_5860428_13 - - - - 0.00000000000000000000000000000000000000000003785 169.0
TLS3_k127_5860428_14 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000002331 145.0
TLS3_k127_5860428_15 CRS1_YhbY K07574 - - 0.00000000000000000000000000000000002946 138.0
TLS3_k127_5860428_18 Bulb-type mannose-specific lectin - - - 0.00000000000000000009639 101.0
TLS3_k127_5860428_19 Beta-lactamase - - - 0.000000000001629 81.0
TLS3_k127_5860428_2 PFAM chorismate K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 475.0
TLS3_k127_5860428_20 FG-GAP repeat - - - 0.000001851 52.0
TLS3_k127_5860428_5 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 336.0
TLS3_k127_5860428_6 transcriptional regulator K18297 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 297.0
TLS3_k127_5860428_8 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000000009228 229.0
TLS3_k127_5860428_9 - - - - 0.00000000000000000000000000000000000000000000000000000001133 209.0
TLS3_k127_5869134_0 protein conserved in bacteria - - - 1.188e-243 785.0
TLS3_k127_5869134_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 589.0
TLS3_k127_5869134_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 400.0
TLS3_k127_5869134_4 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000001133 159.0
TLS3_k127_5869134_5 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000696 82.0
TLS3_k127_5872014_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 9.143e-223 693.0
TLS3_k127_5872014_1 - - - - 0.0000000001472 73.0
TLS3_k127_5872014_2 Metallo-beta-lactamase superfamily - - - 0.000006207 58.0
TLS3_k127_587309_0 Enoylreductase K12436,K16396,K16397 - - 0.0 1134.0
TLS3_k127_587309_1 Hydroxymethylglutaryl-coenzyme A synthase C terminal K15311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 499.0
TLS3_k127_587309_2 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 375.0
TLS3_k127_587309_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 366.0
TLS3_k127_587309_4 Cytochrome P450 K16400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 311.0
TLS3_k127_587309_5 Enoyl-CoA hydratase/isomerase K15312 - - 0.000000000000000000000000000000000000000000000000000000000002153 219.0
TLS3_k127_587309_6 thioesterase involved in non-ribosomal peptide biosynthesis K01071 - 3.1.2.21 0.00000000000000000000000000000000000000000000000000000000005489 214.0
TLS3_k127_587309_7 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000001544 216.0
TLS3_k127_587309_8 Phosphopantetheine attachment site K02078 - - 0.00000000000001725 78.0
TLS3_k127_5875548_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 4.64e-303 940.0
TLS3_k127_5875548_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 436.0
TLS3_k127_5875548_2 Belongs to the FPP GGPP synthase family K00805,K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 438.0
TLS3_k127_5875548_3 phospho-2-dehydro-3-deoxyheptonate aldolase K01626,K03856,K04516,K13853 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 445.0
TLS3_k127_5875548_4 chorismate binding enzyme K01851,K02361,K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 344.0
TLS3_k127_5875548_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 296.0
TLS3_k127_5875548_6 Belongs to the GbsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007546 269.0
TLS3_k127_5875548_7 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.0000000000000000000000000000000000000000000000000000000000001537 232.0
TLS3_k127_5885172_0 Bacterial protein of unknown function (DUF839) K07093 - - 9.514e-308 976.0
TLS3_k127_5885172_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 5.35e-264 834.0
TLS3_k127_5885172_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 391.0
TLS3_k127_5885172_11 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 379.0
TLS3_k127_5885172_12 lipid kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 367.0
TLS3_k127_5885172_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 349.0
TLS3_k127_5885172_16 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009926 293.0
TLS3_k127_5885172_19 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000005087 222.0
TLS3_k127_5885172_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol - - - 2.003e-206 663.0
TLS3_k127_5885172_20 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000001271 222.0
TLS3_k127_5885172_21 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000001704 226.0
TLS3_k127_5885172_22 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000001115 211.0
TLS3_k127_5885172_23 Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N- methyltransferase family K11437 GO:0000122,GO:0000785,GO:0002682,GO:0003674,GO:0003682,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008469,GO:0008757,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010639,GO:0010646,GO:0016043,GO:0016273,GO:0016274,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018193,GO:0018195,GO:0018216,GO:0019219,GO:0019222,GO:0019538,GO:0019919,GO:0023051,GO:0031056,GO:0031057,GO:0031060,GO:0031061,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031399,GO:0031400,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032269,GO:0032502,GO:0033043,GO:0033044,GO:0033554,GO:0034641,GO:0034969,GO:0034970,GO:0035241,GO:0035242,GO:0035246,GO:0035247,GO:0036211,GO:0042054,GO:0042393,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043985,GO:0044020,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045637,GO:0045652,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051239,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051276,GO:0051569,GO:0051572,GO:0051716,GO:0060255,GO:0065007,GO:0070013,GO:0070611,GO:0070612,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090398,GO:0140096,GO:1901360,GO:1901564,GO:1901796,GO:1902275,GO:1902531,GO:1902679,GO:1903506,GO:1903507,GO:1903706,GO:1905268,GO:2000026,GO:2000112,GO:2000113,GO:2001141,GO:2001251 2.1.1.319 0.00000000000000000000000000000000000000000000000000001573 200.0
TLS3_k127_5885172_25 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.0000000000000000000000000000000000007298 151.0
TLS3_k127_5885172_26 LysR substrate binding domain - - - 0.00000000000000000000000000001297 128.0
TLS3_k127_5885172_27 - - - - 0.00000000000000000000000000001888 120.0
TLS3_k127_5885172_28 protein-disulfide reductase activity - - - 0.000000000000000000003844 105.0
TLS3_k127_5885172_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 564.0
TLS3_k127_5885172_32 Belongs to the peptidase S1B family K01318 - 3.4.21.19 0.0000000001163 72.0
TLS3_k127_5885172_33 Pretoxin HINT domain K03646 - - 0.000000004244 64.0
TLS3_k127_5885172_4 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 537.0
TLS3_k127_5885172_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 467.0
TLS3_k127_5885172_6 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 457.0
TLS3_k127_5885172_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 475.0
TLS3_k127_5885172_8 HAMP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 431.0
TLS3_k127_5893547_0 Ca-dependent carbohydrate-binding module xylan-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 548.0
TLS3_k127_5893547_1 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 451.0
TLS3_k127_5893547_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 433.0
TLS3_k127_5893547_3 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 406.0
TLS3_k127_5893547_4 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003041 261.0
TLS3_k127_5893547_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001319 275.0
TLS3_k127_5893547_6 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000002348 195.0
TLS3_k127_5893547_7 - - - - 0.000000000000000007083 88.0
TLS3_k127_5893547_8 Thioredoxin - - - 0.0000000000858 68.0
TLS3_k127_5893547_9 peptidyl-prolyl cis-trans isomerase activity K03769,K03770,K07533 - 5.2.1.8 0.000005871 52.0
TLS3_k127_5904559_0 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0 1648.0
TLS3_k127_5904559_10 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.0000000000000005609 80.0
TLS3_k127_5904559_11 von Willebrand factor, type A K11912 - 2.7.11.1 0.000000000000000671 87.0
TLS3_k127_5904559_12 - - - - 0.00000000002552 71.0
TLS3_k127_5904559_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 419.0
TLS3_k127_5904559_3 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 394.0
TLS3_k127_5904559_4 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 419.0
TLS3_k127_5904559_5 non-ribosomal peptide synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 376.0
TLS3_k127_5904559_6 Zinc-dependent metalloprotease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 334.0
TLS3_k127_5904559_7 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 300.0
TLS3_k127_5904559_8 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000009725 184.0
TLS3_k127_5904559_9 Vitamin K-dependent gamma-carboxylase - - - 0.000000000000000000000000000000000000000003545 167.0
TLS3_k127_5925926_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 429.0
TLS3_k127_5925926_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000937 270.0
TLS3_k127_5925926_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000009294 80.0
TLS3_k127_5935199_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 6.239e-215 705.0
TLS3_k127_5935199_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 550.0
TLS3_k127_5935199_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 457.0
TLS3_k127_5935199_3 Belongs to the peptidase S51 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 379.0
TLS3_k127_5935199_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000117 168.0
TLS3_k127_5935199_8 Belongs to the phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000001723 129.0
TLS3_k127_5935199_9 - - - - 0.00003882 56.0
TLS3_k127_5936767_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1628.0
TLS3_k127_5936767_1 PrkA serine protein kinase C-terminal domain - - - 0.0 1238.0
TLS3_k127_5936767_10 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 437.0
TLS3_k127_5936767_11 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 410.0
TLS3_k127_5936767_12 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 404.0
TLS3_k127_5936767_13 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 415.0
TLS3_k127_5936767_14 TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 372.0
TLS3_k127_5936767_15 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 327.0
TLS3_k127_5936767_16 AAA ATPase domain K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 293.0
TLS3_k127_5936767_17 transmembrane transporter activity K02445,K07783 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000309 274.0
TLS3_k127_5936767_18 PFAM peptidase S51 dipeptidase E K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000000005455 246.0
TLS3_k127_5936767_19 PFAM Dual specificity - - - 0.0000000000000000000000000000000000000000000000000000000000005381 215.0
TLS3_k127_5936767_2 Mur ligase, middle domain protein K03802 - 6.3.2.29,6.3.2.30 0.0 1113.0
TLS3_k127_5936767_21 - - - - 0.000000000001272 76.0
TLS3_k127_5936767_22 His Kinase A (phosphoacceptor) domain K11231,K19691 GO:0000155,GO:0000156,GO:0000160,GO:0000161,GO:0000165,GO:0001932,GO:0001933,GO:0002831,GO:0002833,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004888,GO:0005034,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006469,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0007231,GO:0007234,GO:0008150,GO:0008152,GO:0009607,GO:0009628,GO:0009892,GO:0009927,GO:0009987,GO:0010033,GO:0010563,GO:0010570,GO:0010605,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0030447,GO:0031098,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033554,GO:0033673,GO:0033993,GO:0035556,GO:0036180,GO:0036211,GO:0038023,GO:0040007,GO:0040008,GO:0042221,GO:0042325,GO:0042326,GO:0043086,GO:0043170,GO:0043412,GO:0043549,GO:0044092,GO:0044182,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045927,GO:0045936,GO:0046677,GO:0046777,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0051403,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071310,GO:0071396,GO:0071470,GO:0071704,GO:0071944,GO:0080090,GO:0090033,GO:0097305,GO:0097306,GO:0097307,GO:0097308,GO:0104004,GO:0140096,GO:1900428,GO:1900430,GO:1900443,GO:1900445,GO:1901564,GO:1901700,GO:1901701 2.7.13.3 0.00005127 46.0
TLS3_k127_5936767_23 pilus organization K01083 - 3.1.3.8 0.00009228 53.0
TLS3_k127_5936767_3 Flavin containing amine oxidoreductase - - - 4.135e-250 779.0
TLS3_k127_5936767_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 4.918e-215 680.0
TLS3_k127_5936767_5 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 587.0
TLS3_k127_5936767_6 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 546.0
TLS3_k127_5936767_7 GMP synthase (glutamine-hydrolyzing) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 464.0
TLS3_k127_5936767_9 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 430.0
TLS3_k127_5948016_10 Protein of unknown function (DUF1698) K15257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 370.0
TLS3_k127_5948016_11 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 359.0
TLS3_k127_5948016_12 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000082 285.0
TLS3_k127_5948016_13 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000848 241.0
TLS3_k127_5948016_14 Domain of unknown function (DUF4202) - - - 0.0000000000000000000000000000000000000000000000000000000000000001982 228.0
TLS3_k127_5948016_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000005767 234.0
TLS3_k127_5948016_16 - - - - 0.00000000000000000000002575 101.0
TLS3_k127_5948016_17 Transcriptional regulator - - - 0.0000000000000000000009191 105.0
TLS3_k127_5948016_18 - - - - 0.00000000000000000002906 93.0
TLS3_k127_5948016_19 - - - - 0.0008198 50.0
TLS3_k127_5948016_2 Glycosyl transferases group 1 K06320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 513.0
TLS3_k127_5948016_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 496.0
TLS3_k127_5948016_4 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 488.0
TLS3_k127_5948016_5 thiamine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 497.0
TLS3_k127_5948016_7 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 484.0
TLS3_k127_5948016_8 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 458.0
TLS3_k127_5948016_9 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 433.0
TLS3_k127_5952886_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 2.674e-231 725.0
TLS3_k127_5952886_1 low-complexity proteins - - - 7.227e-223 714.0
TLS3_k127_5952886_10 Domain of unknown function (DUF4150) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007311 236.0
TLS3_k127_5952886_11 phage-related replication protein - - - 0.000000000000000000000000000000000000000000000000889 193.0
TLS3_k127_5952886_14 neuron death in response to oxidative stress K01173 - - 0.00000000000712 75.0
TLS3_k127_5952886_15 Domain of unknown function (DUF4880) K07165 - - 0.00000000008844 73.0
TLS3_k127_5952886_16 ECF sigma factor - - - 0.0000000003381 68.0
TLS3_k127_5952886_17 Photosynthesis system II assembly factor YCF48 - - - 0.000007277 58.0
TLS3_k127_5952886_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 541.0
TLS3_k127_5952886_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 458.0
TLS3_k127_5952886_4 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 415.0
TLS3_k127_5952886_5 Belongs to the glycosyl hydrolase family 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 368.0
TLS3_k127_5952886_7 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 355.0
TLS3_k127_5952886_8 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002681 285.0
TLS3_k127_5952886_9 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004812 284.0
TLS3_k127_5960477_0 Dynamin family - - - 0.0 1299.0
TLS3_k127_5960477_1 unfolded protein binding K18640 - - 0.0 1233.0
TLS3_k127_5960477_10 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000001989 67.0
TLS3_k127_5960477_2 Carbohydrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 570.0
TLS3_k127_5960477_4 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 432.0
TLS3_k127_5960477_5 Protein serine threonine phosphatase K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 382.0
TLS3_k127_5960477_6 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 366.0
TLS3_k127_5960477_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000009641 137.0
TLS3_k127_5960477_9 GDSL-like Lipase/Acylhydrolase family - - - 0.00000001067 69.0
TLS3_k127_5973833_0 protein conserved in bacteria K11891 - - 0.0 1530.0
TLS3_k127_5973833_1 Belongs to the ClpA ClpB family K11907 - - 0.0 1459.0
TLS3_k127_5973833_10 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 286.0
TLS3_k127_5973833_11 protein conserved in bacteria K11906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 284.0
TLS3_k127_5973833_2 protein conserved in bacteria K11900 - - 1.87e-303 932.0
TLS3_k127_5973833_3 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 9.534e-254 786.0
TLS3_k127_5973833_4 Transglycosylase SLT domain K08307 - - 2.755e-207 661.0
TLS3_k127_5973833_5 Forkhead associated domain K11894,K11913 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 605.0
TLS3_k127_5973833_6 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 530.0
TLS3_k127_5973833_7 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ K11910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 473.0
TLS3_k127_5973833_8 Type VI secretion system protein DotU K11892 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 389.0
TLS3_k127_6006390_0 Superfamily II DNA RNA helicases, SNF2 family - - - 0.0 1617.0
TLS3_k127_6006390_1 ErfK ybiS ycfS ynhG family protein - - - 9.179e-251 783.0
TLS3_k127_6006390_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 367.0
TLS3_k127_6006390_6 - - - - 0.0000000000000000000000000000000008614 137.0
TLS3_k127_6006390_7 InterPro IPR007367 - - - 0.000000000000000003588 93.0
TLS3_k127_60170_0 Heat shock 70 kDa protein - - - 6.411e-265 825.0
TLS3_k127_60170_1 - - - - 4.558e-252 786.0
TLS3_k127_60170_10 nitric oxide dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000754 175.0
TLS3_k127_60170_11 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000005116 157.0
TLS3_k127_60170_12 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000005865 148.0
TLS3_k127_60170_13 - - - - 0.000000000000000000000000000000007098 146.0
TLS3_k127_60170_14 COG2346 Truncated hemoglobins K06886 - - 0.00000000000000000000000002206 113.0
TLS3_k127_60170_15 lyase activity - - - 0.0000000003659 73.0
TLS3_k127_60170_2 phosphorelay signal transduction system K02282,K20971 - - 1.68e-238 760.0
TLS3_k127_60170_3 Protein of unknown function (DUF1588) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 581.0
TLS3_k127_60170_4 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 428.0
TLS3_k127_60170_5 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 362.0
TLS3_k127_60170_6 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 353.0
TLS3_k127_60170_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 324.0
TLS3_k127_60170_8 Oxidoreductase FAD-binding domain K00491,K21832 - 1.14.14.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001059 309.0
TLS3_k127_60170_9 Domain of unknown function (DUF3369) - - - 0.000000000000000000000000000000000000000000000034 190.0
TLS3_k127_6030810_0 Belongs to the ompA family - - - 1.175e-236 752.0
TLS3_k127_6030810_1 - - - - 2.676e-214 685.0
TLS3_k127_6030810_2 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004424 257.0
TLS3_k127_6045197_0 nodulation K00612 - - 6.126e-242 762.0
TLS3_k127_6045197_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 588.0
TLS3_k127_6045197_10 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000004576 207.0
TLS3_k127_6045197_11 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000003023 168.0
TLS3_k127_6045197_12 ATPase involved in DNA repair K03546 - - 0.000000000000000000000000000000559 141.0
TLS3_k127_6045197_14 ATPase involved in DNA K03546 - - 0.0000000000000000000002964 113.0
TLS3_k127_6045197_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00993,K00994,K13644 GO:0000139,GO:0001558,GO:0003674,GO:0003824,GO:0004142,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0006629,GO:0006644,GO:0006650,GO:0006656,GO:0006657,GO:0006663,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0017169,GO:0019637,GO:0019992,GO:0031090,GO:0031984,GO:0040008,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046469,GO:0046470,GO:0046474,GO:0046486,GO:0050789,GO:0050794,GO:0051128,GO:0065007,GO:0071704,GO:0090407,GO:0097164,GO:0098588,GO:0098791,GO:1901564,GO:1901566,GO:1901576 2.7.8.1,2.7.8.2 0.0000000000000002877 91.0
TLS3_k127_6045197_16 - - - - 0.0000000773 63.0
TLS3_k127_6045197_19 - - - - 0.000002931 61.0
TLS3_k127_6045197_2 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 555.0
TLS3_k127_6045197_20 - - - - 0.000008759 58.0
TLS3_k127_6045197_21 His Kinase A (phosphoacceptor) domain K11231,K19691 GO:0000155,GO:0000156,GO:0000160,GO:0000161,GO:0000165,GO:0001932,GO:0001933,GO:0002831,GO:0002833,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004888,GO:0005034,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006469,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0007231,GO:0007234,GO:0008150,GO:0008152,GO:0009607,GO:0009628,GO:0009892,GO:0009927,GO:0009987,GO:0010033,GO:0010563,GO:0010570,GO:0010605,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0030447,GO:0031098,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033554,GO:0033673,GO:0033993,GO:0035556,GO:0036180,GO:0036211,GO:0038023,GO:0040007,GO:0040008,GO:0042221,GO:0042325,GO:0042326,GO:0043086,GO:0043170,GO:0043412,GO:0043549,GO:0044092,GO:0044182,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045927,GO:0045936,GO:0046677,GO:0046777,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0051403,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071310,GO:0071396,GO:0071470,GO:0071704,GO:0071944,GO:0080090,GO:0090033,GO:0097305,GO:0097306,GO:0097307,GO:0097308,GO:0104004,GO:0140096,GO:1900428,GO:1900430,GO:1900443,GO:1900445,GO:1901564,GO:1901700,GO:1901701 2.7.13.3 0.00005127 46.0
TLS3_k127_6045197_3 integral membrane protein K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 502.0
TLS3_k127_6045197_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 432.0
TLS3_k127_6045197_5 Sigma-54 interaction domain K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 435.0
TLS3_k127_6045197_7 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 399.0
TLS3_k127_6045197_8 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 290.0
TLS3_k127_6045197_9 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005689 259.0
TLS3_k127_6059209_0 Family membership - - - 3.799e-304 979.0
TLS3_k127_6059209_1 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000005108 221.0
TLS3_k127_6082880_0 - - - - 0.0 1090.0
TLS3_k127_6082880_1 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 412.0
TLS3_k127_6082880_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000007231 250.0
TLS3_k127_608750_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 4.82e-200 639.0
TLS3_k127_608750_1 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 564.0
TLS3_k127_608750_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 573.0
TLS3_k127_608750_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 328.0
TLS3_k127_608750_4 Arginine-tRNA-protein transferase, C terminus K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000004855 185.0
TLS3_k127_608750_5 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000002801 166.0
TLS3_k127_608750_7 Endonuclease I K07004 - - 0.0000000000000000000006589 107.0
TLS3_k127_608750_9 Putative transposase, YhgA-like - - - 0.00000000000000002034 85.0
TLS3_k127_6089817_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 2.634e-240 781.0
TLS3_k127_6089817_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 6.784e-230 756.0
TLS3_k127_6089817_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 475.0
TLS3_k127_6089817_3 Glycosyl hydrolases family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 383.0
TLS3_k127_610271_0 Protein of unknown function DUF58 - - - 3.416e-233 733.0
TLS3_k127_610271_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 571.0
TLS3_k127_610271_2 MCM2/3/5 family K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 537.0
TLS3_k127_610271_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 379.0
TLS3_k127_610271_4 ATP binding K06926 - - 0.000000000000000000000159 109.0
TLS3_k127_610271_6 AAA ATPase domain - - - 0.0000003315 63.0
TLS3_k127_6130786_0 protein kinase activity - - - 6.081e-233 762.0
TLS3_k127_6130786_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 446.0
TLS3_k127_6130786_3 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000001358 215.0
TLS3_k127_6130786_4 GtrA-like protein - - - 0.000007294 54.0
TLS3_k127_6131920_0 involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1238.0
TLS3_k127_6131920_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.05e-245 767.0
TLS3_k127_6131920_2 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 361.0
TLS3_k127_6131920_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 342.0
TLS3_k127_6131920_4 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000002028 240.0
TLS3_k127_6131920_5 Inhibitor of apoptosis-promoting Bax1 K06890,K19416 - - 0.0000000000000000000000000000000000000000000000000000000000001933 232.0
TLS3_k127_6154680_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 3.89e-300 945.0
TLS3_k127_6154680_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004168 274.0
TLS3_k127_6154680_2 methyltransferase - - - 0.000000000000000001117 90.0
TLS3_k127_6162067_0 PFAM Protein kinase domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000001489 235.0
TLS3_k127_6162067_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000009775 164.0
TLS3_k127_6162067_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000004033 132.0
TLS3_k127_6162067_3 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000005261 118.0
TLS3_k127_6162067_5 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000003089 94.0
TLS3_k127_6162067_6 - - - - 0.00000000003409 76.0
TLS3_k127_6162067_7 DNA-templated transcription, initiation - - - 0.000000001436 68.0
TLS3_k127_6166565_0 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 399.0
TLS3_k127_6166565_1 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 321.0
TLS3_k127_6166565_2 Domain of unknown function (DUF4150) - - - 0.0000000000000000000000000000000000000001154 153.0
TLS3_k127_6166565_3 Protein of unknown function (DUF3540) - - - 0.000000000000000000000000000000000000001419 158.0
TLS3_k127_6166565_4 - - - - 0.00000000000000000000000000000000247 132.0
TLS3_k127_6166565_5 Phenazine biosynthesis-like protein - - - 0.000000000000000000004852 97.0
TLS3_k127_6166565_6 Protein of unknown function (DUF433) - - - 0.0000000000000001194 85.0
TLS3_k127_6166565_7 Protein of unknown function (DUF861) - - - 0.000000000009281 77.0
TLS3_k127_6166565_8 SnoaL-like domain - - - 0.00002436 52.0
TLS3_k127_6175029_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 1.833e-293 914.0
TLS3_k127_6175029_1 4Fe-4S dicluster domain - - - 5.829e-216 688.0
TLS3_k127_6175029_11 NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 347.0
TLS3_k127_6175029_12 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 302.0
TLS3_k127_6175029_13 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 296.0
TLS3_k127_6175029_14 pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001881 264.0
TLS3_k127_6175029_15 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000002615 215.0
TLS3_k127_6175029_17 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000000000000000000000003268 176.0
TLS3_k127_6175029_18 guanyl-nucleotide exchange factor activity K17713 - - 0.00000000000000000000000000000000006263 148.0
TLS3_k127_6175029_19 spore germination K03605 - - 0.00000000000000000000000007473 112.0
TLS3_k127_6175029_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 3.726e-214 696.0
TLS3_k127_6175029_20 HupF/HypC family K04653 - - 0.000000000000000000000439 97.0
TLS3_k127_6175029_21 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000814 107.0
TLS3_k127_6175029_22 COG3209 Rhs family protein - - - 0.0000000000001015 81.0
TLS3_k127_6175029_23 - - - - 0.000000002874 64.0
TLS3_k127_6175029_3 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 589.0
TLS3_k127_6175029_4 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 479.0
TLS3_k127_6175029_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 430.0
TLS3_k127_6175029_6 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 425.0
TLS3_k127_6175029_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 440.0
TLS3_k127_6175029_8 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 407.0
TLS3_k127_6175029_9 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 398.0
TLS3_k127_619790_0 oligosaccharyl transferase activity - - - 1.464e-244 774.0
TLS3_k127_619790_1 Belongs to the thiolase family K00626 - 2.3.1.9 2.054e-199 627.0
TLS3_k127_619790_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001637 282.0
TLS3_k127_619790_11 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001249 282.0
TLS3_k127_619790_13 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.0000000000000000000000000000000000001529 149.0
TLS3_k127_619790_14 Highly conserved protein containing a thioredoxin domain - - - 0.0000000000000000000000000000000002125 153.0
TLS3_k127_619790_15 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000000001114 141.0
TLS3_k127_619790_16 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000607 110.0
TLS3_k127_619790_17 guanyl-nucleotide exchange factor activity K20276 - - 0.000000001812 72.0
TLS3_k127_619790_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 619.0
TLS3_k127_619790_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 592.0
TLS3_k127_619790_4 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane K11103 GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0006950,GO:0006974,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015138,GO:0015140,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015366,GO:0015556,GO:0015672,GO:0015711,GO:0015740,GO:0015741,GO:0015743,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0033554,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070778,GO:0071422,GO:0071423,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902475,GO:1902600,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 470.0
TLS3_k127_619790_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 392.0
TLS3_k127_619790_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 348.0
TLS3_k127_619790_7 PFAM peptidase M13 K01415 - 3.4.24.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 362.0
TLS3_k127_619790_8 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 336.0
TLS3_k127_619790_9 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 320.0
TLS3_k127_62125_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 446.0
TLS3_k127_62125_1 Histidine kinase HAMP K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 351.0
TLS3_k127_62125_10 - - - - 0.00000000000005675 74.0
TLS3_k127_62125_11 Putative transposase, YhgA-like - - - 0.00002439 51.0
TLS3_k127_62125_12 - - - - 0.000047 50.0
TLS3_k127_62125_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 358.0
TLS3_k127_62125_3 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001349 290.0
TLS3_k127_62125_4 Acetohydroxy acid isomeroreductase, NADPH-binding domain K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000004634 256.0
TLS3_k127_62125_5 May be involved in the folding of the extracellular lipase during its passage through the periplasm - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001623 252.0
TLS3_k127_62125_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000008231 229.0
TLS3_k127_62125_7 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000004165 194.0
TLS3_k127_62125_8 Transcriptional regulator - - - 0.00000000000000000000000000000000000001336 161.0
TLS3_k127_62125_9 Peptidase M50 - - - 0.00000000000000000007237 99.0
TLS3_k127_6225854_0 SMART helicase c2 K03722 - 3.6.4.12 1.788e-287 901.0
TLS3_k127_6225854_1 GMC oxidoreductase - - - 6.675e-255 816.0
TLS3_k127_6225854_11 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 317.0
TLS3_k127_6225854_13 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001132 283.0
TLS3_k127_6225854_14 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000008219 258.0
TLS3_k127_6225854_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001459 233.0
TLS3_k127_6225854_19 iron-sulfur cluster assembly K07126,K13819 - - 0.000000000000000000000000000000000000001189 148.0
TLS3_k127_6225854_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 5.715e-247 767.0
TLS3_k127_6225854_20 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000001302 151.0
TLS3_k127_6225854_23 carbon-nitrogen ligase activity, with glutamine as amido-N-donor K09117 - - 0.000000000000000000005957 97.0
TLS3_k127_6225854_25 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000006547 76.0
TLS3_k127_6225854_27 G8 - - - 0.00009917 55.0
TLS3_k127_6225854_28 SMART regulatory protein GntR HTH K03710 - - 0.0008033 50.0
TLS3_k127_6225854_3 Belongs to the peptidase M16 family K07263 - - 2.909e-208 664.0
TLS3_k127_6225854_4 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 610.0
TLS3_k127_6225854_5 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 479.0
TLS3_k127_6225854_7 TRANSCRIPTIONal K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 455.0
TLS3_k127_6225854_9 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 405.0
TLS3_k127_622940_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.673e-305 942.0
TLS3_k127_622940_1 oxidoreductase activity K07114 - - 1.265e-292 937.0
TLS3_k127_622940_2 Aminotransferase K10907 - - 4.822e-196 619.0
TLS3_k127_622940_3 TIGRFAM MATE efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 500.0
TLS3_k127_622940_4 LytTr DNA-binding domain K02477,K07705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001439 273.0
TLS3_k127_622940_5 Cytosol aminopeptidase family, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001123 240.0
TLS3_k127_622940_6 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000007706 157.0
TLS3_k127_622940_8 xyloglucan:xyloglucosyl transferase activity - - - 0.000000000001083 78.0
TLS3_k127_622940_9 LytTr DNA-binding domain K02477,K07705 - - 0.000004807 51.0
TLS3_k127_6232853_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.535e-293 939.0
TLS3_k127_6232853_1 7TM receptor with intracellular HD hydrolase K07037 - - 1.62e-258 812.0
TLS3_k127_6232853_10 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 364.0
TLS3_k127_6232853_11 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 343.0
TLS3_k127_6232853_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 362.0
TLS3_k127_6232853_13 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 346.0
TLS3_k127_6232853_14 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 324.0
TLS3_k127_6232853_15 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 297.0
TLS3_k127_6232853_17 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000024 192.0
TLS3_k127_6232853_18 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000006012 201.0
TLS3_k127_6232853_2 COG1233 Phytoene dehydrogenase and related - - - 1.567e-255 801.0
TLS3_k127_6232853_20 thiolester hydrolase activity - - - 0.0000000004898 74.0
TLS3_k127_6232853_21 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000004823 64.0
TLS3_k127_6232853_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 556.0
TLS3_k127_6232853_4 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 549.0
TLS3_k127_6232853_5 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 543.0
TLS3_k127_6232853_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 438.0
TLS3_k127_6232853_7 YbbR-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 368.0
TLS3_k127_6232853_8 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 369.0
TLS3_k127_6232853_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 356.0
TLS3_k127_6245212_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 4.836e-271 845.0
TLS3_k127_6245212_1 Peptidase dimerisation domain - - - 1.96e-233 732.0
TLS3_k127_6245212_2 Sodium/hydrogen exchanger family K03316 - - 9.981e-212 672.0
TLS3_k127_6245212_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 454.0
TLS3_k127_6245212_4 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 364.0
TLS3_k127_6245212_5 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001785 286.0
TLS3_k127_6245212_6 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000001239 52.0
TLS3_k127_626172_0 WD40-like Beta Propeller Repeat - - - 0.0 1271.0
TLS3_k127_626172_1 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 462.0
TLS3_k127_626172_2 Formyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 442.0
TLS3_k127_626172_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 435.0
TLS3_k127_626172_4 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 387.0
TLS3_k127_626172_6 ATPase involved in DNA repair - - - 0.000000000000003335 89.0
TLS3_k127_626172_8 Cytidylyltransferase K07257 - - 0.0000004698 52.0
TLS3_k127_6275879_0 Family membership - - - 0.0 1390.0
TLS3_k127_6275879_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 453.0
TLS3_k127_6275879_10 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000006093 110.0
TLS3_k127_6275879_11 DDE superfamily endonuclease - - - 0.00000000000000000009629 103.0
TLS3_k127_6275879_12 COG5659 FOG Transposase - - - 0.0000000000001351 73.0
TLS3_k127_6275879_14 GlnD PII-uridylyltransferase - - - 0.0001689 55.0
TLS3_k127_6275879_2 PFAM Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 322.0
TLS3_k127_6275879_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001395 261.0
TLS3_k127_6275879_5 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000001318 207.0
TLS3_k127_6275879_6 Domain of unknown function (DUF4123) - - - 0.00000000000000000000000000000000000000000000000000000000237 205.0
TLS3_k127_6275879_7 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000002558 199.0
TLS3_k127_6275879_9 PFAM small multidrug resistance protein K11741 - - 0.000000000000000000000000000000000000000001352 158.0
TLS3_k127_629027_0 MMPL family K03296 - - 0.0 1234.0
TLS3_k127_629027_1 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 545.0
TLS3_k127_629027_2 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 466.0
TLS3_k127_629027_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 388.0
TLS3_k127_629027_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001205 267.0
TLS3_k127_629027_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000003842 165.0
TLS3_k127_6298184_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.139e-257 812.0
TLS3_k127_6298184_1 Domain of unknown function (DUF4388) - - - 5.604e-208 655.0
TLS3_k127_6298184_2 Peptidase dimerisation domain K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 563.0
TLS3_k127_6298184_3 Methyltransferase type 12 - - - 0.0000000000000000000001226 110.0
TLS3_k127_6314160_0 Insulinase (Peptidase family M16) K07263 - - 6.765e-231 722.0
TLS3_k127_6314160_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 601.0
TLS3_k127_6314160_11 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000000000000002091 223.0
TLS3_k127_6314160_12 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000629 197.0
TLS3_k127_6314160_13 Biotin-requiring enzyme K02160 - - 0.00000000000000000000000000004715 117.0
TLS3_k127_6314160_14 - - - - 0.00000000000000000002221 94.0
TLS3_k127_6314160_15 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000007963 83.0
TLS3_k127_6314160_16 - - - - 0.0000004367 57.0
TLS3_k127_6314160_17 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000168 58.0
TLS3_k127_6314160_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 529.0
TLS3_k127_6314160_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 520.0
TLS3_k127_6314160_4 Beta-eliminating lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 406.0
TLS3_k127_6314160_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 337.0
TLS3_k127_6314160_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004404 280.0
TLS3_k127_6314160_7 Domain of unknown function (4846) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009417 283.0
TLS3_k127_6314160_8 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000002077 278.0
TLS3_k127_6314160_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004206 238.0
TLS3_k127_6344712_0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 347.0
TLS3_k127_6344712_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000002173 92.0
TLS3_k127_6344712_2 Galactose oxidase, central domain - - - 0.0000000000000000004039 101.0
TLS3_k127_6344712_3 M61 glycyl aminopeptidase - - - 0.0000000000000001475 94.0
TLS3_k127_6344712_4 Bacterial regulatory proteins, tetR family - - - 0.000000007071 57.0
TLS3_k127_6345481_0 Flagellar basal body rod K02396 - - 1.564e-246 781.0
TLS3_k127_6345481_1 PFAM Archaeal ATPase - - - 4.21e-217 685.0
TLS3_k127_6345481_11 Von Willebrand factor type A - - - 0.0000000000000000000000001107 124.0
TLS3_k127_6345481_12 Aerotolerance regulator N-terminal - - - 0.000000000000000009404 98.0
TLS3_k127_6345481_13 AAA ATPase domain - - - 0.0000000002999 63.0
TLS3_k127_6345481_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 500.0
TLS3_k127_6345481_3 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 387.0
TLS3_k127_6345481_4 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 329.0
TLS3_k127_6345481_5 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 293.0
TLS3_k127_6345481_6 ATPase associated with K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 309.0
TLS3_k127_6345481_7 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009848 271.0
TLS3_k127_6345481_8 protein with SCP PR1 domains - - - 0.0000000000000000000000000000000000000000000000000000000000000005213 226.0
TLS3_k127_6345481_9 SEC-C Motif Domain Protein K09858 - - 0.0000000000000000000000000000000000000000000000001414 201.0
TLS3_k127_6345547_0 Dehydrogenase K00052 - 1.1.1.85 1.261e-200 629.0
TLS3_k127_6345547_1 bacterial-type flagellum organization K02411 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 368.0
TLS3_k127_6345547_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 337.0
TLS3_k127_6345547_3 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 287.0
TLS3_k127_6345547_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000123 287.0
TLS3_k127_6345547_6 DNA integration - - - 0.000000002825 65.0
TLS3_k127_6384714_0 PFAM Alcohol dehydrogenase - - - 1.796e-204 642.0
TLS3_k127_6384714_1 Zinc metalloprotease (Elastase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 533.0
TLS3_k127_6384714_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 456.0
TLS3_k127_6384714_3 transposase or invertase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 374.0
TLS3_k127_6384714_4 ThiJ/PfpI family-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 374.0
TLS3_k127_6384714_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 301.0
TLS3_k127_6384714_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 300.0
TLS3_k127_6384714_7 Protein kinase domain - - - 0.000000000000000000000000000000000000002573 165.0
TLS3_k127_6418770_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1836.0
TLS3_k127_6418770_1 Glycogen debranching enzyme - - - 0.0 1343.0
TLS3_k127_6418770_11 Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001784 257.0
TLS3_k127_6418770_12 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008844 237.0
TLS3_k127_6418770_13 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000005812 208.0
TLS3_k127_6418770_14 hydrolase activity, acting on ester bonds K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000009195 194.0
TLS3_k127_6418770_15 PFAM CHAD domain containing protein - - - 0.00000000000000000000000000000000000000000000001886 193.0
TLS3_k127_6418770_17 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000000000000000000000000000000000001707 151.0
TLS3_k127_6418770_18 Universal stress protein family - - - 0.000000000000000000000000000000000000004844 149.0
TLS3_k127_6418770_2 Tetratricopeptide repeat - - - 0.0 1065.0
TLS3_k127_6418770_20 Lamin Tail Domain K00703,K01990,K02519,K11904 - 2.4.1.21 0.00000000000000000000000177 118.0
TLS3_k127_6418770_21 Jacalin-like lectin domain - - - 0.00000000000000003063 96.0
TLS3_k127_6418770_22 COG2931, RTX toxins and related Ca2 -binding proteins K01729,K20276 - 4.2.2.3 0.00000002436 67.0
TLS3_k127_6418770_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.691e-229 726.0
TLS3_k127_6418770_4 Signal peptide peptidase K04773 - - 1.724e-197 635.0
TLS3_k127_6418770_5 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 387.0
TLS3_k127_6418770_6 bacterial-type flagellum organization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 350.0
TLS3_k127_6418770_7 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 310.0
TLS3_k127_6418770_8 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 301.0
TLS3_k127_6418770_9 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001863 299.0
TLS3_k127_643351_0 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 298.0
TLS3_k127_643351_1 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 293.0
TLS3_k127_643351_2 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001235 279.0
TLS3_k127_643351_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000000000005772 109.0
TLS3_k127_6434080_0 Sulfatase K01133 - 3.1.6.6 3.907e-239 761.0
TLS3_k127_6434080_1 ERAP1-like C-terminal domain - - - 3.112e-232 748.0
TLS3_k127_6434080_10 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit - - - 0.00000000000000000000000000000000000000007086 168.0
TLS3_k127_6434080_11 - - - - 0.00000000000000000000000000008329 134.0
TLS3_k127_6434080_12 von Willebrand factor type A domain K07114 - - 0.000000000000000000000000001464 128.0
TLS3_k127_6434080_13 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000159 84.0
TLS3_k127_6434080_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 506.0
TLS3_k127_6434080_3 Amidohydrolase family K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 500.0
TLS3_k127_6434080_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 408.0
TLS3_k127_6434080_5 S-adenosyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 383.0
TLS3_k127_6434080_8 Belongs to the sterol desaturase family K00227 - 1.14.19.20 0.000000000000000000000000000000000000000000000000000000000000004497 227.0
TLS3_k127_6434080_9 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000008966 222.0
TLS3_k127_6437968_0 - - - - 0.0 1276.0
TLS3_k127_6437968_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 597.0
TLS3_k127_6437968_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 469.0
TLS3_k127_6437968_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 436.0
TLS3_k127_6437968_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 411.0
TLS3_k127_6437968_5 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 347.0
TLS3_k127_6437968_6 Belongs to the Dps family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006151 250.0
TLS3_k127_6437968_7 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000002843 240.0
TLS3_k127_6437968_9 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000005065 116.0
TLS3_k127_6450281_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 466.0
TLS3_k127_6450281_10 cellulose binding - - - 0.0000000004203 73.0
TLS3_k127_6450281_12 PEGA domain - - - 0.000002341 61.0
TLS3_k127_6450281_2 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 321.0
TLS3_k127_6450281_4 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000148 216.0
TLS3_k127_6450281_5 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000004467 193.0
TLS3_k127_6450281_6 - - - - 0.0000000000000000000000000004259 131.0
TLS3_k127_6450281_7 peptidoglycan biosynthetic process - - - 0.000000000000000000000001372 111.0
TLS3_k127_6450281_8 Domain of unknown function (DUF4157) - - - 0.00000000000000002344 96.0
TLS3_k127_6450281_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000001981 80.0
TLS3_k127_6455263_0 Condensation domain - - - 3.066e-301 1004.0
TLS3_k127_6455263_1 Beta-ketoacyl synthase, N-terminal domain - - - 3.128e-293 963.0
TLS3_k127_6455263_10 Saccharopine dehydrogenase NADP binding domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000002326 180.0
TLS3_k127_6455263_11 - - - - 0.00000000000000000003618 100.0
TLS3_k127_6455263_12 Phosphopantetheine attachment site K02078 - - 0.00000000000000000003809 92.0
TLS3_k127_6455263_13 - - - - 0.0000000000000000724 90.0
TLS3_k127_6455263_2 Beta-ketoacyl synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 625.0
TLS3_k127_6455263_3 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 550.0
TLS3_k127_6455263_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 490.0
TLS3_k127_6455263_5 Prolyl oligopeptidase family K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 460.0
TLS3_k127_6455263_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 327.0
TLS3_k127_6455263_7 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001084 284.0
TLS3_k127_6455263_8 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003909 283.0
TLS3_k127_6455263_9 PFAM Hydroxymethylglutaryl-coenzyme A synthase K01641,K15311 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000002462 250.0
TLS3_k127_649588_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 306.0
TLS3_k127_649588_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 301.0
TLS3_k127_649588_3 TIGRFAM PEP-CTERM protein sorting domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008355 240.0
TLS3_k127_649588_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000001616 216.0
TLS3_k127_649588_5 PilZ domain - - - 0.0000000000000000000000000000001342 128.0
TLS3_k127_649588_6 - - - - 0.0000000000000000000002621 112.0
TLS3_k127_6508827_0 PEGA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 545.0
TLS3_k127_6508827_1 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 377.0
TLS3_k127_6508827_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 362.0
TLS3_k127_6508827_3 Kelch motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 308.0
TLS3_k127_6508827_4 Rhs family - - - 0.00000000000000000000000000000000000000001561 169.0
TLS3_k127_6508827_5 Protein of unknown function (DUF416) K09891 - - 0.00003595 54.0
TLS3_k127_6557965_0 Rhs family - - - 0.0 1693.0
TLS3_k127_6557965_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 3.557e-215 673.0
TLS3_k127_6557965_10 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000004135 274.0
TLS3_k127_6557965_11 PBP superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001564 242.0
TLS3_k127_6557965_12 - - - - 0.00000000000000000000000000000000000000000000000000000009268 200.0
TLS3_k127_6557965_13 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000004589 171.0
TLS3_k127_6557965_14 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000003484 94.0
TLS3_k127_6557965_16 Histidine kinase - - - 0.000000000000009049 83.0
TLS3_k127_6557965_18 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000001881 62.0
TLS3_k127_6557965_19 Histidine kinase - - - 0.0000000003312 67.0
TLS3_k127_6557965_2 Rhs family - - - 3.911e-206 660.0
TLS3_k127_6557965_3 Outer membrane efflux protein - - - 1.991e-199 633.0
TLS3_k127_6557965_4 phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 466.0
TLS3_k127_6557965_5 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 439.0
TLS3_k127_6557965_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 332.0
TLS3_k127_6557965_7 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 326.0
TLS3_k127_6557965_8 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 307.0
TLS3_k127_6557965_9 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 296.0
TLS3_k127_6569122_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 542.0
TLS3_k127_6569122_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 465.0
TLS3_k127_6569122_4 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 362.0
TLS3_k127_6569122_5 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 361.0
TLS3_k127_6569122_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 342.0
TLS3_k127_6569122_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 323.0
TLS3_k127_6579893_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 1.952e-241 770.0
TLS3_k127_6579893_1 beta-lactamase - - - 7.652e-220 713.0
TLS3_k127_6579893_10 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000007416 253.0
TLS3_k127_6579893_11 cheY-homologous receiver domain - - - 0.000000000000000000000000002731 130.0
TLS3_k127_6579893_13 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00001109 58.0
TLS3_k127_6579893_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 486.0
TLS3_k127_6579893_3 Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA K00219,K09461 - 1.14.13.40,1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 434.0
TLS3_k127_6579893_4 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 439.0
TLS3_k127_6579893_5 Peptidase T2, asparaginase 2 K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 426.0
TLS3_k127_6579893_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 368.0
TLS3_k127_6579893_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 350.0
TLS3_k127_6579893_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001473 302.0
TLS3_k127_6579893_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001848 251.0
TLS3_k127_6605326_0 Peptidase S46 - - - 2.605e-286 899.0
TLS3_k127_6605326_1 RNB K01147,K12573 - 3.1.13.1 9.138e-199 628.0
TLS3_k127_6605326_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 554.0
TLS3_k127_6605326_3 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 552.0
TLS3_k127_6605326_4 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 347.0
TLS3_k127_6605326_5 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 304.0
TLS3_k127_6605326_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009766 244.0
TLS3_k127_6605326_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000002103 260.0
TLS3_k127_6605326_8 - - - - 0.0000000000000004296 83.0
TLS3_k127_661399_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 614.0
TLS3_k127_661399_2 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 513.0
TLS3_k127_661399_3 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000002284 219.0
TLS3_k127_661399_4 ThiS family - - - 0.0000000000000000000000000007319 115.0
TLS3_k127_6654595_0 CoA-substrate-specific enzyme activase - - - 0.0 2183.0
TLS3_k127_6654595_1 4 iron, 4 sulfur cluster binding - - - 0.0 1016.0
TLS3_k127_6654595_10 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000001461 196.0
TLS3_k127_6654595_2 Predicted nucleotidyltransferase K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 530.0
TLS3_k127_6654595_3 helix_turn_helix, Lux Regulon K02479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 338.0
TLS3_k127_6654595_4 Predicted nucleotidyltransferase K07074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 329.0
TLS3_k127_6654595_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000499 265.0
TLS3_k127_6654595_7 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000001103 227.0
TLS3_k127_6654595_8 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000000000000000000287 205.0
TLS3_k127_6720928_0 UvrD/REP helicase N-terminal domain - - - 0.0 1392.0
TLS3_k127_6720928_1 PD-(D/E)XK nuclease superfamily - - - 0.0 1188.0
TLS3_k127_6720928_10 cheY-homologous receiver domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000008352 269.0
TLS3_k127_6720928_11 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001698 274.0
TLS3_k127_6720928_12 ABC-type spermidine putrescine transport system, permease component II K02053,K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001103 255.0
TLS3_k127_6720928_13 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000002574 238.0
TLS3_k127_6720928_14 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000000000000000000000000000009261 185.0
TLS3_k127_6720928_15 - - - - 0.000000000000000000000000000000000000000000000000002767 188.0
TLS3_k127_6720928_16 - - - - 0.000000000000000000000000000000000009584 149.0
TLS3_k127_6720928_17 Anti-anti sigma factor protein K17763 - - 0.0000000000000000000000000000000000808 147.0
TLS3_k127_6720928_2 Aldehyde dehydrogenase family K00130 - 1.2.1.8 1.256e-239 749.0
TLS3_k127_6720928_20 AraC-type transcriptional regulator N-terminus - - - 0.000000000000009683 81.0
TLS3_k127_6720928_21 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000002227 70.0
TLS3_k127_6720928_3 His Kinase A (phosphoacceptor) domain - - - 7.668e-225 729.0
TLS3_k127_6720928_4 Involved in the tonB-independent uptake of proteins - - - 1.426e-215 683.0
TLS3_k127_6720928_5 Aminotransferase class-III K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 499.0
TLS3_k127_6720928_6 Belongs to the ABC transporter superfamily K02010,K11072 - 3.6.3.30,3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 385.0
TLS3_k127_6720928_7 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 361.0
TLS3_k127_6720928_8 protein kinase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 347.0
TLS3_k127_6720928_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 302.0
TLS3_k127_6731640_0 PFAM NAD-dependent epimerase dehydratase K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 482.0
TLS3_k127_6731640_1 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 469.0
TLS3_k127_6731640_2 GDP-mannose 4,6 dehydratase K19180 - 1.1.1.339 0.000000000000000000000000000000000000000000000000000000000000000000000000000001099 269.0
TLS3_k127_6731640_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000000000000002349 91.0
TLS3_k127_6749123_0 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 313.0
TLS3_k127_6749123_2 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000002433 170.0
TLS3_k127_6749123_3 - - - - 0.0000000000000000000000000000401 121.0
TLS3_k127_6749123_4 bacterial-type flagellum organization K02411 - - 0.0000000000001313 78.0
TLS3_k127_6749123_5 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000002364 76.0
TLS3_k127_6749123_6 - - - - 0.00000009213 59.0
TLS3_k127_6749123_7 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0005763 44.0
TLS3_k127_6786949_0 ERCC3/RAD25/XPB C-terminal helicase - - - 3.002e-217 682.0
TLS3_k127_6786949_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 537.0
TLS3_k127_6786949_10 6-pyruvoyl tetrahydropterin synthase - - - 0.0000000000000000000000000000000000000000000000006585 188.0
TLS3_k127_6786949_11 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K01647,K22491 - 2.3.3.1 0.0000000000000000000000004819 111.0
TLS3_k127_6786949_12 - - - - 0.000001965 59.0
TLS3_k127_6786949_13 cellulose binding - - - 0.0007098 51.0
TLS3_k127_6786949_2 Protein of unknown function (DUF790) K09744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 514.0
TLS3_k127_6786949_3 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 284.0
TLS3_k127_6786949_4 COG0419 ATPase involved in DNA repair K03546 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006260,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006343 289.0
TLS3_k127_6786949_5 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001784 255.0
TLS3_k127_6786949_6 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000001406 233.0
TLS3_k127_6786949_7 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000008392 205.0
TLS3_k127_6786949_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K00082,K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000001046 190.0
TLS3_k127_6786949_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000001986 192.0
TLS3_k127_679036_0 SWIM zinc finger - - - 8.14e-237 772.0
TLS3_k127_679036_1 - - - - 1.387e-200 648.0
TLS3_k127_679036_2 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 3.525e-196 621.0
TLS3_k127_679036_3 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 468.0
TLS3_k127_679036_4 - - - - 0.000000000000000000000000000001029 133.0
TLS3_k127_6796157_0 Non-ribosomal peptide - - - 0.0 3080.0
TLS3_k127_6796157_1 TIGRFAM amino acid adenylation domain - - - 0.0 1943.0
TLS3_k127_6903590_0 serine threonine protein kinase - - - 1.665e-317 1000.0
TLS3_k127_6903590_1 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 422.0
TLS3_k127_6903590_2 Acetyltransferase (GNAT) domain K03817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 347.0
TLS3_k127_6903590_3 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000001257 217.0
TLS3_k127_6903590_4 - - - - 0.0000000000000000000000000000009708 125.0
TLS3_k127_6903590_5 - - - - 0.00000002047 56.0
TLS3_k127_6912471_0 Belongs to the ompA family - - - 2.162e-212 688.0
TLS3_k127_6912471_1 PEGA domain - - - 1.572e-209 669.0
TLS3_k127_6912471_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 537.0
TLS3_k127_6912471_3 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 449.0
TLS3_k127_6912471_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 421.0
TLS3_k127_6912471_5 WD-40 repeat - - - 0.00000000000000000000000000000000000000000000000000000000005995 210.0
TLS3_k127_6912471_7 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000003047 66.0
TLS3_k127_6922597_0 AcrB/AcrD/AcrF family K07788 - - 0.0 1440.0
TLS3_k127_6922597_1 MMPL family K07789 - - 0.0 1281.0
TLS3_k127_6922597_2 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 359.0
TLS3_k127_6922597_3 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000002815 213.0
TLS3_k127_6924898_0 MaoC like domain K14449,K18290 - 4.2.1.148,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 514.0
TLS3_k127_6924898_1 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000002404 213.0
TLS3_k127_6924898_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000005429 166.0
TLS3_k127_6931854_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1482.0
TLS3_k127_6931854_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1045.0
TLS3_k127_6931854_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 433.0
TLS3_k127_6931854_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 421.0
TLS3_k127_6931854_12 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 414.0
TLS3_k127_6931854_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 387.0
TLS3_k127_6931854_14 VTC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 361.0
TLS3_k127_6931854_15 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 377.0
TLS3_k127_6931854_16 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 370.0
TLS3_k127_6931854_17 Domain of unknown function (DUF4956) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 343.0
TLS3_k127_6931854_18 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 347.0
TLS3_k127_6931854_19 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 339.0
TLS3_k127_6931854_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 6.027e-267 849.0
TLS3_k127_6931854_20 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
TLS3_k127_6931854_21 acid phosphatase activity K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 291.0
TLS3_k127_6931854_22 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003022 263.0
TLS3_k127_6931854_23 Acyl-CoA thioester hydrolase bile acid-CoA amino acid N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001824 259.0
TLS3_k127_6931854_25 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000001218 198.0
TLS3_k127_6931854_27 Acyl-ACP thioesterase K07107 - - 0.000000000000000000000000000000000009512 144.0
TLS3_k127_6931854_29 Horizontally Transferred TransMembrane Domain - - - 0.0007822 51.0
TLS3_k127_6931854_3 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 1.458e-246 770.0
TLS3_k127_6931854_4 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 625.0
TLS3_k127_6931854_5 acid phosphatase activity K22390 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 558.0
TLS3_k127_6931854_6 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 531.0
TLS3_k127_6931854_7 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 518.0
TLS3_k127_6931854_8 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 516.0
TLS3_k127_6931854_9 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 430.0
TLS3_k127_6934399_0 heat shock protein binding K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 538.0
TLS3_k127_6934399_1 Aldo Keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 500.0
TLS3_k127_6934399_2 LysR substrate binding domain K18297 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 411.0
TLS3_k127_6934399_3 Protein of unknown function (DUF1016) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 294.0
TLS3_k127_6934399_4 fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000002279 226.0
TLS3_k127_6934399_5 STAS domain K17763 - - 0.00000000000000000000000000000003028 130.0
TLS3_k127_6934399_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000001783 70.0
TLS3_k127_6947733_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1437.0
TLS3_k127_6947733_1 Protein kinase domain K12132 - 2.7.11.1 0.0 1090.0
TLS3_k127_6947733_10 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 383.0
TLS3_k127_6947733_11 Belongs to the TPP enzyme family K01568,K04103 - 4.1.1.1,4.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 365.0
TLS3_k127_6947733_12 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 337.0
TLS3_k127_6947733_13 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 321.0
TLS3_k127_6947733_14 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 314.0
TLS3_k127_6947733_15 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000000000000000000000000000000000000009155 236.0
TLS3_k127_6947733_16 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000000000000000000000005045 201.0
TLS3_k127_6947733_17 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000001682 194.0
TLS3_k127_6947733_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000662 164.0
TLS3_k127_6947733_2 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 9.257e-235 752.0
TLS3_k127_6947733_21 S1 P1 nuclease - - - 0.00000000000000000000001922 114.0
TLS3_k127_6947733_22 deoxyhypusine monooxygenase activity - - - 0.00000000000001837 82.0
TLS3_k127_6947733_3 transcription factor binding K21405 - - 6.158e-208 655.0
TLS3_k127_6947733_4 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 595.0
TLS3_k127_6947733_5 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 532.0
TLS3_k127_6947733_6 Helix-turn-helix domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 464.0
TLS3_k127_6947733_7 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 452.0
TLS3_k127_6947733_8 Belongs to the peptidase S8 family K01400,K01417,K20274 - 3.4.24.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 448.0
TLS3_k127_6947733_9 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 384.0
TLS3_k127_6953314_0 Vinylacetyl-CoA Delta-isomerase K14534 - 4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 423.0
TLS3_k127_6953314_1 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 389.0
TLS3_k127_6953314_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 310.0
TLS3_k127_6953314_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000005015 228.0
TLS3_k127_6953314_4 regulation of circadian rhythm - - - 0.00000000000000000000000000000000000000008853 160.0
TLS3_k127_6953314_5 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000000000001527 120.0
TLS3_k127_6953314_6 protein kinase activity - - - 0.000000000001469 74.0
TLS3_k127_6953314_7 Protein of unknown function (DUF952) - - - 0.000006308 52.0
TLS3_k127_6954831_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 601.0
TLS3_k127_6954831_1 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 381.0
TLS3_k127_6954831_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000134 278.0
TLS3_k127_6954831_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000001492 229.0
TLS3_k127_6954831_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000005567 212.0
TLS3_k127_6954831_5 SMI1-KNR4 cell-wall - - - 0.0000000000000000000000000000002053 128.0
TLS3_k127_6954831_6 Rhs family - - - 0.000000000000000000000000001462 125.0
TLS3_k127_6954831_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000009194 93.0
TLS3_k127_6954831_9 metal-dependent phosphohydrolase HD region - - - 0.00001248 53.0
TLS3_k127_700589_0 COGs COG1020 Non-ribosomal peptide synthetase modules and related protein - - - 2.809e-263 837.0
TLS3_k127_700589_1 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001328 234.0
TLS3_k127_700589_2 Phage integrase family - - - 0.0000000000000000000000000000001605 130.0
TLS3_k127_700589_3 Integrase core domain K07497 - - 0.00001613 51.0
TLS3_k127_7030512_0 Vault protein inter-alpha-trypsin domain - - - 0.0 1225.0
TLS3_k127_7030512_1 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 586.0
TLS3_k127_7030512_10 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000006509 224.0
TLS3_k127_7030512_11 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000009454 205.0
TLS3_k127_7030512_12 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000005416 207.0
TLS3_k127_7030512_13 - - - - 0.000001522 51.0
TLS3_k127_7030512_2 GHKL domain K07641 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 547.0
TLS3_k127_7030512_3 Belongs to the long-chain O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 486.0
TLS3_k127_7030512_4 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 389.0
TLS3_k127_7030512_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 392.0
TLS3_k127_7030512_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 388.0
TLS3_k127_7030512_7 Transcriptional regulatory protein, C terminal K07663,K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 370.0
TLS3_k127_7050843_0 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 485.0
TLS3_k127_7050843_1 protein conserved in bacteria K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 439.0
TLS3_k127_7050843_10 endonuclease I - - - 0.0000000000000000000000002112 119.0
TLS3_k127_7050843_12 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000007387 94.0
TLS3_k127_7050843_14 Antibiotic biosynthesis monooxygenase - - - 0.0008329 48.0
TLS3_k127_7050843_2 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 413.0
TLS3_k127_7050843_3 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 424.0
TLS3_k127_7050843_5 Protein of unknown function (DUF2167) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 325.0
TLS3_k127_7050843_6 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004113 252.0
TLS3_k127_7050843_7 N-4 methylation of cytosine K00571,K03497 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000009716 246.0
TLS3_k127_7050843_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005561 248.0
TLS3_k127_7050843_9 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000004497 227.0
TLS3_k127_7058219_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 361.0
TLS3_k127_7058219_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 330.0
TLS3_k127_7058219_2 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001866 249.0
TLS3_k127_7064218_0 ABC transporter transmembrane region K06147,K18890 - - 7.831e-285 892.0
TLS3_k127_7064218_1 ABC transporter K06147,K18889 - - 6.298e-271 867.0
TLS3_k127_7064218_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000005951 199.0
TLS3_k127_7064218_13 Belongs to the bacterial histone-like protein family - - - 0.0000000000000000000000000000000000001558 145.0
TLS3_k127_7064218_2 Protein kinase domain - - - 3.604e-231 733.0
TLS3_k127_7064218_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 1.947e-202 644.0
TLS3_k127_7064218_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 2.606e-194 616.0
TLS3_k127_7064218_5 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 529.0
TLS3_k127_7064218_7 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 350.0
TLS3_k127_7064218_8 LysM domain protein K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 299.0
TLS3_k127_7068836_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.074e-237 743.0
TLS3_k127_7068836_1 ABC1 family - - - 1.665e-215 686.0
TLS3_k127_7068836_3 ATP-NAD kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 409.0
TLS3_k127_7068836_4 nUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008309 284.0
TLS3_k127_7068836_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000002806 221.0
TLS3_k127_7068836_6 PFAM Protein kinase domain K08309 - - 0.000000000000000000000000000000000000000000000002248 184.0
TLS3_k127_7068836_7 Belongs to the bacterial histone-like protein family - - - 0.0000000000000000000000000000000000000000009126 167.0
TLS3_k127_7069139_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 1.233e-209 673.0
TLS3_k127_7069139_1 ABC transporter, transmembrane K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 576.0
TLS3_k127_7069139_10 GDP-fucose protein O-fucosyltransferase - - - 0.000000000000000001639 101.0
TLS3_k127_7069139_11 cellulose binding - - - 0.000000000000003405 88.0
TLS3_k127_7069139_12 - - - - 0.00000008228 61.0
TLS3_k127_7069139_13 acyl carrier protein K02078 - - 0.0000009996 59.0
TLS3_k127_7069139_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003199 261.0
TLS3_k127_7069139_3 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000001455 241.0
TLS3_k127_7069139_4 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000001724 218.0
TLS3_k127_7069139_5 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000006687 198.0
TLS3_k127_7069139_7 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03817 - - 0.000000000000000000000000000004454 126.0
TLS3_k127_7069139_8 - - - - 0.000000000000000000000002177 108.0
TLS3_k127_7069139_9 Non-ribosomal peptide synthetase modules and related proteins - - - 0.00000000000000000008993 103.0
TLS3_k127_7099731_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0 1029.0
TLS3_k127_7099731_1 SMART DNA-directed DNA polymerase B - - - 4.017e-300 940.0
TLS3_k127_7099731_10 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000001204 164.0
TLS3_k127_7099731_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000002022 154.0
TLS3_k127_7099731_12 activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000000000000000000718 125.0
TLS3_k127_7099731_13 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000007105 123.0
TLS3_k127_7099731_14 Protein of unknown function (DUF2778) - - - 0.000001096 61.0
TLS3_k127_7099731_2 protein conserved in bacteria - - - 1.416e-283 889.0
TLS3_k127_7099731_3 protein conserved in bacteria K11904 - - 7.3e-253 809.0
TLS3_k127_7099731_4 Uncharacterized protein conserved in bacteria (DUF2169) - - - 1.362e-228 732.0
TLS3_k127_7099731_5 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 432.0
TLS3_k127_7099731_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001092 285.0
TLS3_k127_7099731_7 Domain of unknown function (DUF4123) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001978 283.0
TLS3_k127_7099731_8 UDP-galactopyranose mutase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000008919 270.0
TLS3_k127_7099731_9 PAAR motif - - - 0.000000000000000000000000000000000000000000000000000004201 192.0
TLS3_k127_7100814_0 lyase activity - - - 0.000000000000000000000001056 106.0
TLS3_k127_7100814_2 AAA domain - - - 0.000000000005533 78.0
TLS3_k127_7103438_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 480.0
TLS3_k127_7103438_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 492.0
TLS3_k127_7103438_2 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 413.0
TLS3_k127_7103438_3 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 338.0
TLS3_k127_7109175_0 Belongs to the heat shock protein 70 family K04043 - - 0.0 1201.0
TLS3_k127_7109175_1 MlaD protein K02067 - - 3.412e-240 750.0
TLS3_k127_7109175_2 Cytochrome c554 and c-prime K01119 - 3.1.3.6,3.1.4.16 4.056e-228 718.0
TLS3_k127_7109175_3 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 469.0
TLS3_k127_7109175_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 406.0
TLS3_k127_7109175_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 383.0
TLS3_k127_7109175_6 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 384.0
TLS3_k127_7109175_7 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000004636 236.0
TLS3_k127_7109175_8 - - - - 0.0000000000000000000000000000000000000000006446 160.0
TLS3_k127_7109175_9 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000003296 92.0
TLS3_k127_7120016_0 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000002667 216.0
TLS3_k127_7120016_1 - - - - 0.0000000000000000000000000000000003377 150.0
TLS3_k127_7123313_0 copper-translocating P-type ATPase K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 360.0
TLS3_k127_7123313_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001702 244.0
TLS3_k127_7123313_2 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000008968 166.0
TLS3_k127_7123313_3 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000000000000000000003558 163.0
TLS3_k127_7123313_4 ubiquinone biosynthetic process - - - 0.0000000000000000000002481 109.0
TLS3_k127_7135700_0 TonB-dependent Receptor Plug Domain - - - 6.355e-264 839.0
TLS3_k127_7135700_1 Purple acid Phosphatase, N-terminal domain - - - 1.929e-252 805.0
TLS3_k127_7135700_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000001741 228.0
TLS3_k127_7135700_11 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000652 230.0
TLS3_k127_7135700_13 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000005048 183.0
TLS3_k127_7135700_14 Domain of unknown function (DUF2383) - - - 0.00000000000000000000000000125 119.0
TLS3_k127_7135700_17 Glucose / Sorbosone dehydrogenase - - - 0.0000000000005256 81.0
TLS3_k127_7135700_19 Tetratricopeptide repeat - - - 0.0000007156 60.0
TLS3_k127_7135700_2 Penicillin amidase K01434 - 3.5.1.11 8.27e-234 747.0
TLS3_k127_7135700_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 6.026e-202 642.0
TLS3_k127_7135700_4 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 545.0
TLS3_k127_7135700_5 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 477.0
TLS3_k127_7135700_6 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 475.0
TLS3_k127_7135700_7 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 430.0
TLS3_k127_7135700_8 BtpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 314.0
TLS3_k127_7135700_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001027 293.0
TLS3_k127_7202933_0 B12 binding domain - - - 1.675e-232 740.0
TLS3_k127_7202933_1 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000007572 201.0
TLS3_k127_7239146_0 helicase domain protein - - - 0.0 1890.0
TLS3_k127_7239146_1 histone H2A K63-linked ubiquitination K03404,K07114 - 6.6.1.1 0.0 1077.0
TLS3_k127_7239146_10 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004231 201.0
TLS3_k127_7239146_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000000018 137.0
TLS3_k127_7239146_12 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000006321 113.0
TLS3_k127_7239146_13 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000007963 83.0
TLS3_k127_7239146_2 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0 1013.0
TLS3_k127_7239146_3 Domain of unknown function (DUF4215) - - - 1.135e-305 966.0
TLS3_k127_7239146_4 Protein of unknown function, DUF255 K06888 - - 8.884e-292 917.0
TLS3_k127_7239146_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 3.682e-238 751.0
TLS3_k127_7239146_6 Belongs to the ompA family K03286 - - 7.358e-211 681.0
TLS3_k127_7239146_7 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 449.0
TLS3_k127_7239146_8 R3H domain K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 299.0
TLS3_k127_7239146_9 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007207 278.0
TLS3_k127_7253026_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1392.0
TLS3_k127_7253026_1 Two component regulator propeller - - - 1.958e-286 930.0
TLS3_k127_7253026_10 glycogenin glucosyltransferase activity K00750 - 2.4.1.186 0.00000000000000000000000000000000000000000001008 173.0
TLS3_k127_7253026_11 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000000000000000000000000009485 140.0
TLS3_k127_7253026_14 START domain - - - 0.00001333 56.0
TLS3_k127_7253026_2 Membrane - - - 6.321e-266 833.0
TLS3_k127_7253026_3 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 529.0
TLS3_k127_7253026_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K10857 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 400.0
TLS3_k127_7253026_5 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 405.0
TLS3_k127_7253026_6 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 396.0
TLS3_k127_7253026_7 cheY-homologous receiver domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002513 281.0
TLS3_k127_7253026_8 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000001701 198.0
TLS3_k127_7257303_0 Methionine synthase K00548 - 2.1.1.13 0.0 2258.0
TLS3_k127_7257303_1 SMART serine threonine protein kinase - - - 2.068e-273 884.0
TLS3_k127_7257303_10 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000000000000000000000000000003893 243.0
TLS3_k127_7257303_11 Protein of unknown function (DUF3037) - - - 0.000000000000000000000000000000000000000000167 169.0
TLS3_k127_7257303_12 SnoaL-like polyketide cyclase - - - 0.000000000006626 78.0
TLS3_k127_7257303_13 - - - - 0.00000000161 70.0
TLS3_k127_7257303_14 CHAT domain - - - 0.00000624 59.0
TLS3_k127_7257303_2 DNA polymerase K02347 - - 5.8e-246 792.0
TLS3_k127_7257303_3 choline dehydrogenase activity K03333 - 1.1.3.6 2.751e-195 635.0
TLS3_k127_7257303_4 Belongs to the peptidase C1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 565.0
TLS3_k127_7257303_5 Involved in cholesterol metabolism catalytic activity cholesterol O(2) cholest-4-en-3-one H(2)O(2) K03333 - 1.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 552.0
TLS3_k127_7257303_6 Alpha-amylase domain K01182,K01187 - 3.2.1.10,3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 533.0
TLS3_k127_7257303_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 516.0
TLS3_k127_7257303_8 Serine threonine protein kinase involved in cell cycle control - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 315.0
TLS3_k127_7257303_9 Dual-action HEIGH metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003687 246.0
TLS3_k127_7258238_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1236.0
TLS3_k127_7258238_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate - - - 4.337e-297 929.0
TLS3_k127_7258238_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000002938 214.0
TLS3_k127_7258238_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000013 238.0
TLS3_k127_7258238_13 cytochrome - - - 0.0000000000000000007883 94.0
TLS3_k127_7258238_15 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000001071 61.0
TLS3_k127_7258238_2 Family membership - - - 1.271e-296 963.0
TLS3_k127_7258238_3 pkhd-type hydroxylase K07336 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 304.0
TLS3_k127_7258238_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 288.0
TLS3_k127_7258238_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009854 260.0
TLS3_k127_7258238_7 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000122 252.0
TLS3_k127_7258238_8 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002435 237.0
TLS3_k127_7258238_9 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000002951 259.0
TLS3_k127_725854_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1389.0
TLS3_k127_725854_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.0 1014.0
TLS3_k127_725854_10 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000000000000000000000002807 154.0
TLS3_k127_725854_11 Forkhead associated domain - - - 0.0000000000000000000000000000002035 130.0
TLS3_k127_725854_12 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000002934 127.0
TLS3_k127_725854_13 SpoVT / AbrB like domain K07172 - - 0.000000000000000000000000007485 111.0
TLS3_k127_725854_14 filamentation induced by cAMP protein Fic - - - 0.000000000004971 75.0
TLS3_k127_725854_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.129e-217 689.0
TLS3_k127_725854_3 adenosine deaminase K01488 - 3.5.4.4 5.659e-201 640.0
TLS3_k127_725854_4 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 409.0
TLS3_k127_725854_6 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 338.0
TLS3_k127_725854_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 324.0
TLS3_k127_725854_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 328.0
TLS3_k127_725854_9 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 270.0
TLS3_k127_7269833_0 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 368.0
TLS3_k127_7269833_1 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 367.0
TLS3_k127_7269833_2 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 297.0
TLS3_k127_7269833_3 Protein conserved in bacteria K09939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005798 262.0
TLS3_k127_7269833_4 - - - - 0.0000000000000000000000000000000055 136.0
TLS3_k127_7269833_7 - - - - 0.00000000000000002518 96.0
TLS3_k127_7299819_0 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 3.042e-250 784.0
TLS3_k127_7299819_1 AAA domain (dynein-related subfamily) - - - 5.533e-212 667.0
TLS3_k127_7299819_10 von Willebrand factor (vWF) type A domain - GO:0006810,GO:0006897,GO:0006909,GO:0008150,GO:0016192,GO:0051179,GO:0051234,GO:0098657 - 0.000005032 60.0
TLS3_k127_7299819_11 beta-lactamase activity K07126 - - 0.00002545 56.0
TLS3_k127_7299819_2 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 509.0
TLS3_k127_7299819_3 VWA-like domain (DUF2201) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 527.0
TLS3_k127_7299819_4 Protein of unknown function, DUF481 K07283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000282 249.0
TLS3_k127_7299819_5 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000000000000194 215.0
TLS3_k127_7299819_6 guanyl-nucleotide exchange factor activity K02034 - - 0.000000000000000000000000000000000000000000001045 188.0
TLS3_k127_7299819_9 PFAM cyclase dehydrase - - - 0.0000001575 62.0
TLS3_k127_7320520_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 416.0
TLS3_k127_7320520_1 carbamoyl transferase, NodU family K00612 - - 0.0000000000000000000000000003086 115.0
TLS3_k127_7320520_2 - - - - 0.00000001637 67.0
TLS3_k127_7327782_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 506.0
TLS3_k127_7327782_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 323.0
TLS3_k127_7327782_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004908 277.0
TLS3_k127_7339768_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 497.0
TLS3_k127_7339768_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 407.0
TLS3_k127_7339768_2 membrane - - - 0.00000000000000000000000002125 114.0
TLS3_k127_7364379_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2606.0
TLS3_k127_7364379_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2582.0
TLS3_k127_7364379_10 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 417.0
TLS3_k127_7364379_11 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 414.0
TLS3_k127_7364379_12 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 345.0
TLS3_k127_7364379_14 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 309.0
TLS3_k127_7364379_15 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008528 270.0
TLS3_k127_7364379_16 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004569 267.0
TLS3_k127_7364379_17 General secretion pathway protein C K02452 - - 0.000000000000000000000000000000000000000000000000000000000000000000001508 248.0
TLS3_k127_7364379_18 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000004648 230.0
TLS3_k127_7364379_19 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000003718 217.0
TLS3_k127_7364379_2 AAA ATPase domain - - - 0.0 1146.0
TLS3_k127_7364379_20 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000001269 203.0
TLS3_k127_7364379_21 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000000000000000000000000000000000002816 203.0
TLS3_k127_7364379_22 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000003146 184.0
TLS3_k127_7364379_23 - - - - 0.0000000000000000000000000000000000000000005969 166.0
TLS3_k127_7364379_24 AAA ATPase domain - - - 0.000000000000000000000000004955 127.0
TLS3_k127_7364379_25 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000004508 116.0
TLS3_k127_7364379_26 Glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.0000000000000002648 78.0
TLS3_k127_7364379_27 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000005044 69.0
TLS3_k127_7364379_28 endonuclease activity - - - 0.00000000004033 72.0
TLS3_k127_7364379_29 protein conserved in cyanobacteria - - - 0.0004737 49.0
TLS3_k127_7364379_3 HD domain - - - 1.794e-265 839.0
TLS3_k127_7364379_4 Aerotolerance regulator N-terminal - - - 2.486e-258 814.0
TLS3_k127_7364379_5 Twitching motility protein PilT K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 561.0
TLS3_k127_7364379_6 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 541.0
TLS3_k127_7364379_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 499.0
TLS3_k127_7364379_8 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 462.0
TLS3_k127_7364379_9 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 434.0
TLS3_k127_7383459_1 Protein conserved in bacteria - - - 7.717e-237 749.0
TLS3_k127_7383459_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 608.0
TLS3_k127_7383459_3 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 580.0
TLS3_k127_7383459_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 386.0
TLS3_k127_7383459_5 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 371.0
TLS3_k127_7383459_6 - - - - 0.0000000000000000000000000000000000000000000000000004977 186.0
TLS3_k127_7383459_7 Protein of unknown function (DUF1275) - - - 0.0000000000000000000000000009168 124.0
TLS3_k127_7383459_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000001313 108.0
TLS3_k127_7404914_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1244.0
TLS3_k127_7404914_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 2.229e-288 902.0
TLS3_k127_7404914_2 Belongs to the peptidase S8 family K14645 - - 3.048e-255 799.0
TLS3_k127_7404914_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 461.0
TLS3_k127_7404914_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K16066 - 1.1.1.381 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 364.0
TLS3_k127_7404914_5 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 331.0
TLS3_k127_7407771_0 - - - - 0.000000000000000000000000000006712 128.0
TLS3_k127_7407771_1 Putative zinc ribbon domain - - - 0.0000000000000000000001316 104.0
TLS3_k127_7407771_2 transcriptional regulator - - - 0.00000000000000000002919 98.0
TLS3_k127_7407771_3 - - - - 0.0000000000001142 80.0
TLS3_k127_7410351_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.816e-277 861.0
TLS3_k127_7410351_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 1.32e-236 777.0
TLS3_k127_7410351_2 Thrombospondin type 3 repeat - - - 7.044e-223 731.0
TLS3_k127_7410351_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 499.0
TLS3_k127_7410351_4 Aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 425.0
TLS3_k127_7410351_5 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 391.0
TLS3_k127_7410351_6 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000001243 246.0
TLS3_k127_7410351_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000001286 239.0
TLS3_k127_7410351_8 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.00000000000000000000000000000001808 134.0
TLS3_k127_7412938_0 ABC-type multidrug transport system ATPase component K21397 - - 0.0 1532.0
TLS3_k127_7412938_1 Periplasmic protein TonB links inner and outer membranes - - - 0.0 1191.0
TLS3_k127_7412938_2 AAA ATPase domain - - - 4.172e-212 707.0
TLS3_k127_7412938_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 531.0
TLS3_k127_7412938_5 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000253 282.0
TLS3_k127_7412938_6 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000008589 228.0
TLS3_k127_7412938_7 - - - - 0.000000000000000007528 91.0
TLS3_k127_7412938_8 Long-chain fatty acid--CoA ligase - - - 0.000000007406 66.0
TLS3_k127_7420988_0 Outer membrane receptor - - - 0.0 1127.0
TLS3_k127_7420988_2 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 428.0
TLS3_k127_7425935_0 RHS Repeat - - - 0.0 1106.0
TLS3_k127_7425935_1 - - - - 0.0000000000000000000000000000002212 129.0
TLS3_k127_7425935_2 Carboxylesterase family K01066 - - 0.00000000000000000000002493 109.0
TLS3_k127_7425935_3 Novel toxin 21 - - - 0.00000000000001123 89.0
TLS3_k127_7425935_4 self proteolysis - - - 0.00000000004318 78.0
TLS3_k127_7428626_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.608e-261 817.0
TLS3_k127_7428626_1 Signal transduction histidine kinase K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 605.0
TLS3_k127_7428626_2 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 490.0
TLS3_k127_7428626_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 456.0
TLS3_k127_7428626_4 Transcriptional regulator, Crp Fnr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 347.0
TLS3_k127_7428626_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 341.0
TLS3_k127_7428626_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 303.0
TLS3_k127_7428626_7 PFAM Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007221 282.0
TLS3_k127_7428626_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000008555 108.0
TLS3_k127_7431335_0 Phage late control gene D protein (GPD) K11904 - - 9.349e-226 717.0
TLS3_k127_7431335_1 Domain of unknown function (DUF4280) - - - 0.00000000000000000000000000000000000000000000000000000003164 198.0
TLS3_k127_7431335_2 PFAM MORN repeat variant - - - 0.0000000000000000000001707 108.0
TLS3_k127_7439579_0 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 556.0
TLS3_k127_7448234_0 - - - - 2.917e-248 819.0
TLS3_k127_7448234_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 3.312e-217 684.0
TLS3_k127_7448234_2 Sugar (and other) transporter - - - 2.105e-205 652.0
TLS3_k127_7448234_4 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 329.0
TLS3_k127_7454811_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 3.36e-322 998.0
TLS3_k127_7454811_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 7.048e-281 878.0
TLS3_k127_7454811_10 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 464.0
TLS3_k127_7454811_11 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 448.0
TLS3_k127_7454811_12 Uncharacterised protein family (UPF0158) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 399.0
TLS3_k127_7454811_13 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 394.0
TLS3_k127_7454811_14 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 317.0
TLS3_k127_7454811_16 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003426 242.0
TLS3_k127_7454811_18 - - - - 0.000000000000000000000000000000000000000000000000002052 197.0
TLS3_k127_7454811_19 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000002109 173.0
TLS3_k127_7454811_2 oxidoreductase activity K07114 - - 3.44e-268 851.0
TLS3_k127_7454811_22 YbbR-like protein - - - 0.0000003431 52.0
TLS3_k127_7454811_23 Transposase Tn5 dimerisation domain - - - 0.0003097 51.0
TLS3_k127_7454811_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.458e-255 796.0
TLS3_k127_7454811_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 1.977e-240 761.0
TLS3_k127_7454811_5 Histidine kinase K13598 - 2.7.13.3 6.343e-237 745.0
TLS3_k127_7454811_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 563.0
TLS3_k127_7454811_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 536.0
TLS3_k127_7454811_8 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 496.0
TLS3_k127_7454811_9 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 486.0
TLS3_k127_7468423_0 Belongs to the glycosyl hydrolase 31 family K01811,K15922 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016798,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777,GO:1990929 3.2.1.177,3.2.1.199 2.807e-314 987.0
TLS3_k127_7468423_1 serine threonine protein kinase - - - 4.927e-214 687.0
TLS3_k127_7468423_2 protein conserved in bacteria K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 622.0
TLS3_k127_7468423_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 368.0
TLS3_k127_7468423_4 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 314.0
TLS3_k127_7468423_5 DcrB - - - 0.00000000000000000000000000000000000000001425 157.0
TLS3_k127_7468423_7 - - - - 0.000000000000000001396 91.0
TLS3_k127_7468423_8 PAAR motif - - - 0.0000000001189 73.0
TLS3_k127_7495082_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 1.795e-299 923.0
TLS3_k127_7495082_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 589.0
TLS3_k127_7495082_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 402.0
TLS3_k127_7495082_11 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 357.0
TLS3_k127_7495082_12 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 342.0
TLS3_k127_7495082_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 332.0
TLS3_k127_7495082_16 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001364 276.0
TLS3_k127_7495082_17 FmdE, Molybdenum formylmethanofuran dehydrogenase operon - - - 0.0000000000000000000000000000000000000000000000000000005515 200.0
TLS3_k127_7495082_18 - - - - 0.0000000000000000000000000000000000000207 158.0
TLS3_k127_7495082_19 - - - - 0.000000000000000000000000000000655 132.0
TLS3_k127_7495082_2 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 541.0
TLS3_k127_7495082_20 cytochrome complex assembly K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.000000000000000000000000000001441 130.0
TLS3_k127_7495082_23 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000003108 63.0
TLS3_k127_7495082_3 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 542.0
TLS3_k127_7495082_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 535.0
TLS3_k127_7495082_5 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 523.0
TLS3_k127_7495082_6 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 517.0
TLS3_k127_7495082_8 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 481.0
TLS3_k127_7495082_9 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 479.0
TLS3_k127_7495441_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 522.0
TLS3_k127_7495441_1 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 397.0
TLS3_k127_7495441_2 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 377.0
TLS3_k127_7495441_3 mevalonate kinase K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 318.0
TLS3_k127_7495441_4 mevalonate kinase activity K00938 - 2.7.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000006992 270.0
TLS3_k127_7495441_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000002783 212.0
TLS3_k127_7495441_6 - - - - 0.000000000000000000000000000000000000000000000000000000005972 229.0
TLS3_k127_7495441_7 antisigma factor binding - - - 0.00000000000000000000000000000000000000000000000000000006972 209.0
TLS3_k127_7495441_9 Immunity protein 51 - - - 0.0000000145 61.0
TLS3_k127_7507879_0 DnaJ molecular chaperone homology domain - - - 0.0 1244.0
TLS3_k127_7507879_1 protein kinase activity - - - 0.0 1152.0
TLS3_k127_7507879_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 586.0
TLS3_k127_7507879_3 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 529.0
TLS3_k127_7507879_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 327.0
TLS3_k127_7507879_5 Fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000006805 244.0
TLS3_k127_7507879_6 CRISPR-associated helicase, Cas3 K07012 - - 0.000000000000000000000000000000000000000000000000002018 186.0
TLS3_k127_7507879_9 - - - - 0.000000000000000000009358 99.0
TLS3_k127_7522517_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 4.588e-218 682.0
TLS3_k127_7522517_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 608.0
TLS3_k127_7522517_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001241 219.0
TLS3_k127_7522517_11 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000000000000000000002657 215.0
TLS3_k127_7522517_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000002247 146.0
TLS3_k127_7522517_13 Ribosomal L32p protein family K02911 - - 0.0000000000000000000000000002379 114.0
TLS3_k127_7522517_14 acetyltransferase K00657 - 2.3.1.57 0.000000000000004912 80.0
TLS3_k127_7522517_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 599.0
TLS3_k127_7522517_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 548.0
TLS3_k127_7522517_4 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 514.0
TLS3_k127_7522517_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 418.0
TLS3_k127_7522517_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 387.0
TLS3_k127_7522517_7 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003431 261.0
TLS3_k127_7522517_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000006395 273.0
TLS3_k127_7522517_9 protein conserved in bacteria K09935 - - 0.0000000000000000000000000000000000000000000000000000000000000000006735 232.0
TLS3_k127_7524002_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 462.0
TLS3_k127_7524002_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 456.0
TLS3_k127_7524002_10 long-chain fatty acid transport protein K06076 - - 0.00000000005791 76.0
TLS3_k127_7524002_11 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000006382 62.0
TLS3_k127_7524002_2 Domain of unknown function (DUF4215) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 413.0
TLS3_k127_7524002_4 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 298.0
TLS3_k127_7524002_5 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001598 266.0
TLS3_k127_7524002_6 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001291 284.0
TLS3_k127_7524002_7 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K13509 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000001484 199.0
TLS3_k127_7524002_9 long-chain fatty acid transport protein K06076 - - 0.000000000000000002578 99.0
TLS3_k127_7532457_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 519.0
TLS3_k127_7532457_1 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000000000000000000006424 162.0
TLS3_k127_7532457_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000001424 140.0
TLS3_k127_7533148_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 4.559e-276 858.0
TLS3_k127_7533148_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 2.003e-254 820.0
TLS3_k127_7533148_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 385.0
TLS3_k127_7533148_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 304.0
TLS3_k127_7533148_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K02487,K03832,K06596 - - 0.00000000000000000000000000000000000000000000000001043 188.0
TLS3_k127_7533148_5 - - - - 0.0000000000000000000001545 106.0
TLS3_k127_7569441_0 - - - - 1.37e-251 808.0
TLS3_k127_7569441_1 Voltage gated chloride channel K03281 - - 1.831e-217 694.0
TLS3_k127_7570426_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 484.0
TLS3_k127_7570426_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 339.0
TLS3_k127_7570426_2 CHRD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 295.0
TLS3_k127_7570426_3 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009068 283.0
TLS3_k127_7570426_4 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002624 276.0
TLS3_k127_7570426_5 Sigma-54 interaction domain K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000008132 245.0
TLS3_k127_7570426_6 indole-3-glycerol-phosphate synthase activity K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000001402 221.0
TLS3_k127_7570426_8 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.000000000000000000000000000008856 124.0
TLS3_k127_7571786_0 Amino acid adenylation domain - - - 1.091e-239 764.0
TLS3_k127_7571786_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000275 174.0
TLS3_k127_7584500_0 PHP domain protein - - - 0.0 1430.0
TLS3_k127_7584500_1 Amidohydrolase family K01466 - 3.5.2.5 3.183e-213 669.0
TLS3_k127_7584500_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000001149 112.0
TLS3_k127_7584500_2 Belongs to the allantoicase family K01477 - 3.5.3.4 5.917e-210 664.0
TLS3_k127_7584500_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.063e-195 616.0
TLS3_k127_7584500_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 482.0
TLS3_k127_7584500_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 383.0
TLS3_k127_7584500_6 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 393.0
TLS3_k127_7584500_7 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007224 258.0
TLS3_k127_7584500_8 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000000000000933 158.0
TLS3_k127_7584500_9 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000002539 144.0
TLS3_k127_7624029_0 PFAM Formylglycine-generating sulfatase enzyme - - - 6.157e-289 921.0
TLS3_k127_7624029_1 TonB dependent receptor K16089 - - 8.194e-236 747.0
TLS3_k127_7624029_10 heme-transporting ATPase activity K02013,K06074 - 3.6.3.33,3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000006025 253.0
TLS3_k127_7624029_11 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000000009293 234.0
TLS3_k127_7624029_12 TonB dependent receptor K16089 - - 0.00000000000000000000000000000000001238 155.0
TLS3_k127_7624029_13 HmuY protein - - - 0.000000000000000000001941 105.0
TLS3_k127_7624029_15 - - - - 0.000004704 52.0
TLS3_k127_7624029_2 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 2.311e-207 651.0
TLS3_k127_7624029_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 448.0
TLS3_k127_7624029_4 Type IV pilus assembly protein PilM; K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 348.0
TLS3_k127_7624029_5 Haem utilisation ChuX/HutX K07225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 353.0
TLS3_k127_7624029_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 357.0
TLS3_k127_7624029_8 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001169 286.0
TLS3_k127_7624452_0 Transglycosylase SLT domain K08307 - - 2.481e-241 774.0
TLS3_k127_7624452_1 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 518.0
TLS3_k127_7624452_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 414.0
TLS3_k127_7624452_3 1-Cys peroxiredoxin K11188 - 1.11.1.15,1.11.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 338.0
TLS3_k127_7624452_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 341.0
TLS3_k127_7624452_5 polysaccharide catabolic process K05991 - 3.2.1.123 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007573 284.0
TLS3_k127_7624452_6 High confidence in function and specificity K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002226 279.0
TLS3_k127_7624452_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000005583 179.0
TLS3_k127_7624452_8 negative regulation of translational initiation - - - 0.000000000000000000000000000000000000000000009277 166.0
TLS3_k127_7629895_0 Sulfatase - - - 1.699e-288 897.0
TLS3_k127_7629895_1 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 2.109e-233 745.0
TLS3_k127_7629895_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.0000000000000000229 92.0
TLS3_k127_7629895_2 Protein of unknown function (DUF2786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 509.0
TLS3_k127_7629895_3 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 421.0
TLS3_k127_7629895_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 403.0
TLS3_k127_7629895_5 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 363.0
TLS3_k127_7629895_6 metal cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
TLS3_k127_7629895_7 Peptidase C26 K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 311.0
TLS3_k127_7629895_8 protein trimerization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 323.0
TLS3_k127_7629895_9 Peptidase family C69 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003699 270.0
TLS3_k127_7639516_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 3.943e-315 989.0
TLS3_k127_7639516_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 1.324e-211 679.0
TLS3_k127_7639516_10 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001807 256.0
TLS3_k127_7639516_11 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000297 197.0
TLS3_k127_7639516_12 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000002688 115.0
TLS3_k127_7639516_13 Belongs to the peptidase S26 family - - - 0.0000000000000000000002919 105.0
TLS3_k127_7639516_2 Transglutaminase-like superfamily - - - 1.15e-208 670.0
TLS3_k127_7639516_3 peptide catabolic process K01256 - 3.4.11.2 2.227e-204 655.0
TLS3_k127_7639516_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 392.0
TLS3_k127_7639516_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 305.0
TLS3_k127_7639516_6 Haloacid dehalogenase-like hydrolase K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 306.0
TLS3_k127_7639516_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 291.0
TLS3_k127_7639516_8 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000008 291.0
TLS3_k127_7639516_9 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000015 274.0
TLS3_k127_7671165_0 Non-ribosomal peptide synthetase modules and related - - - 0.0 1585.0
TLS3_k127_7671165_1 alcohol dehydrogenase K00043 - 1.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 607.0
TLS3_k127_7671165_10 Diguanylate cyclase - - - 0.0000000000000000008934 97.0
TLS3_k127_7671165_2 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 536.0
TLS3_k127_7671165_3 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 449.0
TLS3_k127_7671165_4 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 364.0
TLS3_k127_7671165_8 xylan catabolic process - GO:0005575,GO:0005576 - 0.0000000000000000000000000000001413 125.0
TLS3_k127_7688297_0 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 458.0
TLS3_k127_7688297_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 457.0
TLS3_k127_7688297_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000004501 263.0
TLS3_k127_7688297_3 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002768 283.0
TLS3_k127_7688297_4 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000007438 241.0
TLS3_k127_7693777_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 4.536e-321 1000.0
TLS3_k127_7693777_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 536.0
TLS3_k127_7693777_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 499.0
TLS3_k127_7693777_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 470.0
TLS3_k127_7693777_4 Flavin-binding monooxygenase-like K07222,K18277 - 1.14.13.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 363.0
TLS3_k127_7693777_5 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007555 274.0
TLS3_k127_7693777_6 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000008179 202.0
TLS3_k127_7693777_7 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000001179 63.0
TLS3_k127_7693777_8 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000003939 56.0
TLS3_k127_7693777_9 - - - - 0.0001187 55.0
TLS3_k127_7709673_0 Biotin carboxylase K01961,K01968 - 6.3.4.14,6.4.1.2,6.4.1.4 1.637e-228 714.0
TLS3_k127_7709673_1 COG0515 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 407.0
TLS3_k127_7723326_0 GAF domain K01768 - 4.6.1.1 0.0 1653.0
TLS3_k127_7723326_1 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 2.094e-225 715.0
TLS3_k127_7723326_11 Transcriptional regulator - - - 0.0000000000002565 82.0
TLS3_k127_7723326_2 Chitinase class I K01183 - 3.2.1.14 2.558e-194 613.0
TLS3_k127_7723326_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 561.0
TLS3_k127_7723326_4 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 460.0
TLS3_k127_7723326_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 374.0
TLS3_k127_7723326_6 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005818 272.0
TLS3_k127_7723326_7 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000000000000198 224.0
TLS3_k127_7723326_8 transporter component K07112 - - 0.0000000000000000000000000000000000000008935 154.0
TLS3_k127_7723326_9 Transporter Component K07112 - - 0.000000000000000000000000000000000000002929 158.0
TLS3_k127_7753469_0 TonB-dependent Receptor Plug Domain - - - 6.498e-279 876.0
TLS3_k127_77553_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 536.0
TLS3_k127_77553_1 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 524.0
TLS3_k127_77553_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 424.0
TLS3_k127_77553_3 RNA 2'-phosphotransferase, Tpt1 / KptA family K07559 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001504 265.0
TLS3_k127_77553_4 Putative transposase, YhgA-like - - - 0.00000000000000000000000000000000000000000000000000000000000000003878 229.0
TLS3_k127_7755466_0 DEAD DEAH box K03724 - - 0.0 1907.0
TLS3_k127_7755466_1 Tetratricopeptide repeat - - - 0.0 1299.0
TLS3_k127_7755466_10 InterPro IPR007367 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 353.0
TLS3_k127_7755466_12 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 368.0
TLS3_k127_7755466_13 peptidyl-prolyl cis-trans isomerase activity K02597,K03769,K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 334.0
TLS3_k127_7755466_15 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 293.0
TLS3_k127_7755466_16 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 296.0
TLS3_k127_7755466_17 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004024 273.0
TLS3_k127_7755466_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002746 252.0
TLS3_k127_7755466_2 response regulator K07713 - - 9.786e-257 795.0
TLS3_k127_7755466_20 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000003811 220.0
TLS3_k127_7755466_24 Domain of unknown function (DUF4142) K08995 - - 0.00000000000000000000000000000000000000000125 166.0
TLS3_k127_7755466_25 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000001819 159.0
TLS3_k127_7755466_27 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000003387 128.0
TLS3_k127_7755466_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.006e-248 773.0
TLS3_k127_7755466_30 phospho-2-dehydro-3-deoxyheptonate aldolase - - - 0.00000000002068 73.0
TLS3_k127_7755466_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 619.0
TLS3_k127_7755466_5 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 553.0
TLS3_k127_7755466_6 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 521.0
TLS3_k127_7755466_7 of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 502.0
TLS3_k127_7755466_8 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 417.0
TLS3_k127_7755466_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 416.0
TLS3_k127_7767376_0 Tetratricopeptide repeat - - - 0.0 2080.0
TLS3_k127_7767376_1 COGs COG1020 Non-ribosomal peptide synthetase modules and related protein - - - 0.0 1694.0
TLS3_k127_7767376_2 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.079e-253 869.0
TLS3_k127_7767376_3 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 533.0
TLS3_k127_7767376_4 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795 493.0
TLS3_k127_7767376_5 Protein of unknown function (DUF2804) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 310.0
TLS3_k127_7771856_0 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 427.0
TLS3_k127_7771856_1 Protein of unknown function (DUF1592) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 406.0
TLS3_k127_7771856_2 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 347.0
TLS3_k127_7771856_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 288.0
TLS3_k127_7771856_5 - - - - 0.000001378 53.0
TLS3_k127_7801236_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 5.963e-298 941.0
TLS3_k127_7801236_1 ABC1 family K03688 - - 8.501e-255 796.0
TLS3_k127_7801236_10 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 407.0
TLS3_k127_7801236_11 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 383.0
TLS3_k127_7801236_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 371.0
TLS3_k127_7801236_13 TonB dependent receptor K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 370.0
TLS3_k127_7801236_15 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000019 299.0
TLS3_k127_7801236_16 NMT1-like family K02051,K15551 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000462 269.0
TLS3_k127_7801236_17 Pfam:DUF1795 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005446 254.0
TLS3_k127_7801236_18 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000002519 257.0
TLS3_k127_7801236_2 deoxyhypusine monooxygenase activity K01256,K02563,K08776,K12132 - 2.4.1.227,2.7.11.1,3.4.11.2 4.279e-240 752.0
TLS3_k127_7801236_22 Ring hydroxylating beta subunit - - - 0.0000000000000000000000000000000000000000000000000000002156 200.0
TLS3_k127_7801236_24 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000000007911 149.0
TLS3_k127_7801236_26 Histidine kinase K02482,K03406,K07653,K07654,K17763 GO:0000160,GO:0003674,GO:0003824,GO:0004721,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0040007,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000103 158.0
TLS3_k127_7801236_28 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000000000000000000009101 121.0
TLS3_k127_7801236_3 protein conserved in bacteria K11904 - - 3.006e-198 625.0
TLS3_k127_7801236_30 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535 - 3.5.1.108 0.000000000000000000000004795 116.0
TLS3_k127_7801236_31 beta-lactamase activity K07126,K19292 - - 0.0000000000001618 83.0
TLS3_k127_7801236_33 - - - - 0.000006076 56.0
TLS3_k127_7801236_4 PAAR motif - - - 1.137e-195 620.0
TLS3_k127_7801236_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 598.0
TLS3_k127_7801236_6 protein conserved in bacteria K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 614.0
TLS3_k127_7801236_7 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 545.0
TLS3_k127_7801236_8 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 478.0
TLS3_k127_7801236_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 435.0
TLS3_k127_7833569_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1006.0
TLS3_k127_7833569_1 vancomycin resistance protein K18346 - - 1.336e-263 822.0
TLS3_k127_7833569_10 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000000000000000000000000000000000000000002154 207.0
TLS3_k127_7833569_12 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000001684 143.0
TLS3_k127_7833569_2 Sodium/hydrogen exchanger family - - - 9.184e-207 657.0
TLS3_k127_7833569_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000737 582.0
TLS3_k127_7833569_5 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 416.0
TLS3_k127_7833569_6 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 402.0
TLS3_k127_7833569_7 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 372.0
TLS3_k127_7833569_8 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 353.0
TLS3_k127_7833569_9 CAAX protease self-immunity K06177,K07052,K09696 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000003595 252.0
TLS3_k127_7843060_0 6-phosphogluconolactonase activity - - - 0.0 1226.0
TLS3_k127_7843060_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.192e-275 862.0
TLS3_k127_7843060_10 domain, Protein - - - 0.0000000005322 67.0
TLS3_k127_7843060_12 VWA domain containing CoxE-like protein K09989 - - 0.000000005398 60.0
TLS3_k127_7843060_13 - - - - 0.0002033 46.0
TLS3_k127_7843060_2 Aminotransferase - - - 9.344e-242 760.0
TLS3_k127_7843060_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 552.0
TLS3_k127_7843060_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 460.0
TLS3_k127_7843060_5 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000002854 216.0
TLS3_k127_7843060_6 antisigma factor binding - - - 0.00000000000000000000000000000000000000000000000002028 190.0
TLS3_k127_7843060_7 4-vinyl reductase, 4VR - - - 0.0000000000000000000000000000000000000000000000001041 182.0
TLS3_k127_7843060_8 PFAM Sulfate transporter antisigma-factor antagonist STAS K17763 - - 0.00000000000000000000000000000000000000004767 169.0
TLS3_k127_7843060_9 - - - - 0.000000000000000121 88.0
TLS3_k127_7871182_0 - - - - 8.293e-259 817.0
TLS3_k127_7871182_1 transferase hexapeptide K02617,K03321 - - 1.175e-237 754.0
TLS3_k127_7871182_10 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001911 235.0
TLS3_k127_7871182_11 Anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000004645 225.0
TLS3_k127_7871182_12 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000005962 205.0
TLS3_k127_7871182_13 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000001418 200.0
TLS3_k127_7871182_14 - - - - 0.0000000000000000000000000000000000000000004194 175.0
TLS3_k127_7871182_15 N-terminal glutamine amidase - - - 0.000000000000000000000000000000000103 148.0
TLS3_k127_7871182_16 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000002536 123.0
TLS3_k127_7871182_17 Protein of unknown function (DUF1016) - - - 0.00000000000000000000001732 104.0
TLS3_k127_7871182_2 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 543.0
TLS3_k127_7871182_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 496.0
TLS3_k127_7871182_5 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 337.0
TLS3_k127_7871182_6 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 340.0
TLS3_k127_7871182_7 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 332.0
TLS3_k127_7871182_8 PFAM DAHP synthetase I KDSA K01626,K03856,K13853 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 328.0
TLS3_k127_7871182_9 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000002141 254.0
TLS3_k127_7907420_0 helicase superfamily c-terminal domain K19789 - - 2.422e-246 771.0
TLS3_k127_7907420_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 549.0
TLS3_k127_7907420_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 387.0
TLS3_k127_7907420_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002974 289.0
TLS3_k127_7914143_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 494.0
TLS3_k127_7914143_2 Belongs to the HAD-like hydrolase superfamily. PhnX family K05306 - 3.11.1.1 0.000000000000008844 79.0
TLS3_k127_7914143_4 Redoxin - - - 0.00000005093 65.0
TLS3_k127_7914143_5 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.0000001497 63.0
TLS3_k127_7933672_0 sodium ABC transporter, permease K09696 - - 8.694e-254 807.0
TLS3_k127_7933672_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 5.132e-232 729.0
TLS3_k127_7933672_2 ABC transporter K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 374.0
TLS3_k127_7933672_4 - - - - 0.00000000000000000000000000000000000000002414 165.0
TLS3_k127_7933672_5 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000003708 117.0
TLS3_k127_7933672_7 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000001455 103.0
TLS3_k127_7933672_9 COG1002 Type II restriction enzyme, methylase subunits - - - 0.00001089 55.0
TLS3_k127_7957494_0 Lysin motif K08307 - - 3.545e-246 780.0
TLS3_k127_7957494_1 - - - - 4.504e-231 733.0
TLS3_k127_7957494_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 545.0
TLS3_k127_7973220_0 HipA-like C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 451.0
TLS3_k127_7973220_1 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 317.0
TLS3_k127_7973220_2 TfuA-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 338.0
TLS3_k127_7973220_3 ATP diphosphatase activity K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 305.0
TLS3_k127_7973220_4 RNA methylase K07444 - - 0.0000000000000000000000000000000000000000000000000000001091 213.0
TLS3_k127_7973220_5 - - - - 0.000000000000000000000000000000001063 131.0
TLS3_k127_7973220_6 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.00000001746 63.0
TLS3_k127_7989234_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1377.0
TLS3_k127_7989234_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1024.0
TLS3_k127_7989234_10 Ferredoxin - - - 0.0000000000000000000000000000000000004155 145.0
TLS3_k127_7989234_11 Heme oxygenase - - - 0.000000000000000000000000000000000015 146.0
TLS3_k127_7989234_12 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000001542 141.0
TLS3_k127_7989234_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 4.177e-277 870.0
TLS3_k127_7989234_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 9.697e-218 697.0
TLS3_k127_7989234_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 604.0
TLS3_k127_7989234_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 563.0
TLS3_k127_7989234_6 Ferritin-like domain K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004483 248.0
TLS3_k127_7989234_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000002213 241.0
TLS3_k127_7989234_8 Protein of unknown function (DUF981) K08980 - - 0.000000000000000000000000000000000000000000000000000000000000000201 228.0
TLS3_k127_7989234_9 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000001673 207.0
TLS3_k127_8005830_1 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 538.0
TLS3_k127_8005830_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 495.0
TLS3_k127_8005830_3 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 403.0
TLS3_k127_8005830_6 Peroxidase, family 2 - - - 0.0000000000000000000000002902 115.0
TLS3_k127_8005830_8 Domain of unknown function (DUF378) K09779 - - 0.0000000000000007919 85.0
TLS3_k127_8018968_1 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 565.0
TLS3_k127_8018968_10 pyrroloquinoline quinone binding - - - 0.00000000000000000003163 106.0
TLS3_k127_8018968_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 517.0
TLS3_k127_8018968_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 370.0
TLS3_k127_8018968_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 359.0
TLS3_k127_8018968_5 Phage shock protein A K03969 GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 324.0
TLS3_k127_8018968_6 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000000000000867 187.0
TLS3_k127_8018968_9 proteolysis K02441,K19225 - 3.4.21.105 0.000000000000000000005809 107.0
TLS3_k127_8026646_0 Dynamin family - - - 8.976e-283 880.0
TLS3_k127_8026646_10 low molecular weight - - - 0.0000000000000000000000000000000000000000000000000000000000593 208.0
TLS3_k127_8026646_11 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000000000001455 218.0
TLS3_k127_8026646_14 bacterial-type flagellum organization K02411 - - 0.00000001956 58.0
TLS3_k127_8026646_16 bacterial-type flagellum organization K02411 - - 0.0003215 45.0
TLS3_k127_8026646_17 peptidyl-tyrosine sulfation - - - 0.0009561 48.0
TLS3_k127_8026646_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 596.0
TLS3_k127_8026646_3 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 479.0
TLS3_k127_8026646_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 473.0
TLS3_k127_8026646_5 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 450.0
TLS3_k127_8026646_6 Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 392.0
TLS3_k127_8026646_7 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 375.0
TLS3_k127_8026646_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 335.0
TLS3_k127_8026646_9 bacterial-type flagellum organization - - - 0.000000000000000000000000000000000000000000000000000000000000000001717 231.0
TLS3_k127_8027014_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1566.0
TLS3_k127_8027014_1 Surface antigen - - - 0.0 1164.0
TLS3_k127_8027014_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000002636 223.0
TLS3_k127_8027014_11 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000007899 222.0
TLS3_k127_8027014_12 Redox protein regulator of disulfide bond formation K06889,K07397 - - 0.00000000000000000000000000000000000000000000000001833 185.0
TLS3_k127_8027014_13 Protein of unknown function (DUF2452) - - - 0.0000000000000000000000000000000000000000000259 167.0
TLS3_k127_8027014_14 Cytochrome c K19713 - 1.8.2.2 0.00000000000000000000000000000001023 139.0
TLS3_k127_8027014_2 ABC transporter K06020 - 3.6.3.25 1.193e-307 949.0
TLS3_k127_8027014_3 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 451.0
TLS3_k127_8027014_4 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 437.0
TLS3_k127_8027014_5 Glutathione S-transferase, C-terminal domain K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 403.0
TLS3_k127_8027014_6 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 327.0
TLS3_k127_8027014_7 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002288 292.0
TLS3_k127_8027014_8 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006286 286.0
TLS3_k127_8027014_9 PFAM histone deacetylase superfamily K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006524 275.0
TLS3_k127_8043752_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.247e-264 817.0
TLS3_k127_8043752_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 1.103e-204 646.0
TLS3_k127_8043752_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006483 258.0
TLS3_k127_8043752_3 nuclear chromosome segregation - - - 0.000000007528 68.0
TLS3_k127_8077977_0 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 624.0
TLS3_k127_8077977_1 Protein of unknown function (DUF1587) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 598.0
TLS3_k127_8077977_2 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 491.0
TLS3_k127_8077977_3 Binding-protein-dependent transport system inner membrane component K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 443.0
TLS3_k127_8077977_4 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 408.0
TLS3_k127_8090886_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 6.58e-303 937.0
TLS3_k127_8090886_1 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 429.0
TLS3_k127_8090886_2 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 403.0
TLS3_k127_8090886_3 cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 327.0
TLS3_k127_8090886_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000467 164.0
TLS3_k127_8090886_5 Integrase core domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000004905 70.0
TLS3_k127_810384_0 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 365.0
TLS3_k127_8106075_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1283.0
TLS3_k127_8106075_1 Family membership - - - 0.0 1161.0
TLS3_k127_8106075_2 topoisomerase K02469 - 5.99.1.3 0.0 1125.0
TLS3_k127_8106075_3 DNA topoisomerase K02470,K02622 - 5.99.1.3 5.217e-237 770.0
TLS3_k127_8106075_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 513.0
TLS3_k127_8106075_5 proteolysis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 337.0
TLS3_k127_8106075_6 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 344.0
TLS3_k127_8106075_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
TLS3_k127_8106075_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000005062 169.0
TLS3_k127_8106075_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000001038 132.0
TLS3_k127_8133151_0 Sulfatase - - - 0.0 1271.0
TLS3_k127_8133151_1 acyl-CoA dehydrogenase K09456,K20035 - - 1.193e-320 993.0
TLS3_k127_8133151_10 Cupin superfamily protein - - - 0.000000000000000001506 98.0
TLS3_k127_8133151_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 8.979e-272 862.0
TLS3_k127_8133151_3 PQQ enzyme repeat K17713 - - 1.506e-200 631.0
TLS3_k127_8133151_4 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 355.0
TLS3_k127_8133151_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 357.0
TLS3_k127_8133151_6 Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair K03573 GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009036,GO:0009987,GO:0015666,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019219,GO:0019222,GO:0031323,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0043765,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004353 278.0
TLS3_k127_8133151_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002503 261.0
TLS3_k127_8133151_8 TspO MBR family protein K05770 - - 0.00000000000000000000000000000000000000000000000000002197 193.0
TLS3_k127_8133151_9 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K20276 - - 0.000000000000000000007043 108.0
TLS3_k127_8146052_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1161.0
TLS3_k127_8146052_1 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 535.0
TLS3_k127_8146052_10 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000000000001286 193.0
TLS3_k127_8146052_11 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.0000000000000000000000000000000000000000000000000005741 190.0
TLS3_k127_8146052_13 Transposase IS200 like - - - 0.0000000000000000000000000007939 117.0
TLS3_k127_8146052_14 - - - - 0.000001573 61.0
TLS3_k127_8146052_3 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 443.0
TLS3_k127_8146052_4 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 394.0
TLS3_k127_8146052_6 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 335.0
TLS3_k127_8146052_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 327.0
TLS3_k127_8147443_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1270.0
TLS3_k127_8147443_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 563.0
TLS3_k127_8147443_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 390.0
TLS3_k127_8147443_4 hydrolase activity, acting on ester bonds - - - 0.000000000000000000006363 104.0
TLS3_k127_8148357_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1725.0
TLS3_k127_8148357_1 Sigma-54 interaction domain K07713,K07714,K07715 - - 1.195e-251 786.0
TLS3_k127_8148357_2 Histidine kinase - - - 2.448e-201 640.0
TLS3_k127_8148357_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 510.0
TLS3_k127_8148357_4 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 420.0
TLS3_k127_8148357_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000005832 204.0
TLS3_k127_81559_0 Radical SAM domain protein - - - 0.0 1229.0
TLS3_k127_81559_1 xylan catabolic process K03932 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000134 203.0
TLS3_k127_8164686_0 glucan 1,4-alpha-glucosidase activity - - - 6.362e-300 942.0
TLS3_k127_8164686_1 Malate synthase K01638 - 2.3.3.9 7.085e-248 775.0
TLS3_k127_8164686_11 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.00000000000000000000000000002473 128.0
TLS3_k127_8164686_12 Cytochrome c K08685 - 1.4.9.1 0.000000000004547 78.0
TLS3_k127_8164686_2 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 1.184e-237 739.0
TLS3_k127_8164686_3 Involved in the TonB-independent uptake of proteins K03641 - - 1.826e-202 640.0
TLS3_k127_8164686_4 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 578.0
TLS3_k127_8164686_5 IrrE N-terminal-like domain K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 493.0
TLS3_k127_8164686_6 zinc metalloprotease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 388.0
TLS3_k127_8164686_7 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 300.0
TLS3_k127_8164686_8 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000002844 239.0
TLS3_k127_8164686_9 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000000000000000000000002663 218.0
TLS3_k127_8186536_0 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 513.0
TLS3_k127_8186536_1 Tetratricopeptide repeat - - - 0.00000594 59.0
TLS3_k127_8186536_2 - - - - 0.00005496 50.0
TLS3_k127_8186536_3 recombinase activity - - - 0.0005026 49.0
TLS3_k127_8227273_0 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 497.0
TLS3_k127_8227273_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 482.0
TLS3_k127_8227273_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 477.0
TLS3_k127_8227273_3 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 419.0
TLS3_k127_8227273_4 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 402.0
TLS3_k127_8227273_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 367.0
TLS3_k127_8227273_6 phytanoyl-CoA dioxygenase K00477 - 1.14.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000001022 257.0
TLS3_k127_8229704_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 1.349e-299 929.0
TLS3_k127_8229704_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 8.243e-243 758.0
TLS3_k127_8229704_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 6.317e-223 702.0
TLS3_k127_8229704_3 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 510.0
TLS3_k127_8229704_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 481.0
TLS3_k127_8229704_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000001829 232.0
TLS3_k127_8231798_0 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 4.704e-235 737.0
TLS3_k127_8231798_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008177 563.0
TLS3_k127_8231798_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 525.0
TLS3_k127_8234162_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0 1059.0
TLS3_k127_8234162_1 OmpA family - - - 2.201e-310 969.0
TLS3_k127_8234162_10 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000000000000000000000000000002628 171.0
TLS3_k127_8234162_11 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000001154 164.0
TLS3_k127_8234162_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000002474 147.0
TLS3_k127_8234162_2 PD-(D/E)XK nuclease superfamily - - - 5.082e-259 831.0
TLS3_k127_8234162_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 502.0
TLS3_k127_8234162_4 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 489.0
TLS3_k127_8234162_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 439.0
TLS3_k127_8234162_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 419.0
TLS3_k127_8234162_8 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000002 213.0
TLS3_k127_8238592_0 Belongs to the cytochrome P450 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 353.0
TLS3_k127_8238592_1 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 306.0
TLS3_k127_8238592_3 long-chain fatty acid transport protein - - - 0.000000001251 71.0
TLS3_k127_8238592_4 Protein of unknown function (DUF692) K09930 - - 0.000003394 49.0
TLS3_k127_8338206_0 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 531.0
TLS3_k127_8338206_1 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 445.0
TLS3_k127_8338206_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000006572 265.0
TLS3_k127_8338206_3 Nudix hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000001272 240.0
TLS3_k127_8338206_4 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000003691 155.0
TLS3_k127_8338206_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000001335 77.0
TLS3_k127_8349017_0 Family membership K08884,K12132 - 2.7.11.1 2.293e-218 700.0
TLS3_k127_8349017_2 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 426.0
TLS3_k127_8349017_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 364.0
TLS3_k127_8349017_6 pilus assembly protein PilW K02672 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003674 291.0
TLS3_k127_8349017_7 peptidyl-prolyl cis-trans isomerase activity K03769,K03770,K07533 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000006354 252.0
TLS3_k127_8349017_8 type IV pilus modification protein PilV K02671,K02681 - - 0.000000000000000000000000000000000000000000001293 181.0
TLS3_k127_8349017_9 protein transport across the cell outer membrane K02246,K08084 - - 0.000000000000000000000000001008 122.0
TLS3_k127_8360817_0 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 604.0
TLS3_k127_8360817_1 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 596.0
TLS3_k127_8360817_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000008528 237.0
TLS3_k127_8360817_3 cell envelope organization K05807,K08309 - - 0.000000000000000000000000006688 122.0
TLS3_k127_8360817_4 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.00000000000004503 82.0
TLS3_k127_8394827_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 573.0
TLS3_k127_8394827_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 511.0
TLS3_k127_8394827_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 457.0
TLS3_k127_8394827_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 399.0
TLS3_k127_8402731_0 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 346.0
TLS3_k127_8402731_1 sulfuric ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001146 293.0
TLS3_k127_8402731_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003503 255.0
TLS3_k127_8402731_3 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000001969 244.0
TLS3_k127_8402731_5 - - - - 0.00000000000000000000000000000001118 136.0
TLS3_k127_8402731_6 amine dehydrogenase activity - - - 0.000000000000000000001347 109.0
TLS3_k127_8402731_8 - - - - 0.0000000000001791 78.0
TLS3_k127_8402731_9 protein trimerization - - - 0.0000000000008959 76.0
TLS3_k127_8407716_0 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 422.0
TLS3_k127_8407716_1 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 350.0
TLS3_k127_8407716_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 336.0
TLS3_k127_8407716_3 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008783 290.0
TLS3_k127_8407716_4 Bacterial SH3 domain homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000327 280.0
TLS3_k127_8407716_5 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004105 262.0
TLS3_k127_8407716_6 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000004144 247.0
TLS3_k127_8407716_7 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000001853 217.0
TLS3_k127_8426158_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 3.604e-261 828.0
TLS3_k127_8426158_1 ABC-type oligopeptide transport system periplasmic component K02035,K12368,K13893,K15580,K16199,K19226 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 2.535e-241 773.0
TLS3_k127_8426158_2 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 288.0
TLS3_k127_8426158_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001403 279.0
TLS3_k127_8426158_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000002464 241.0
TLS3_k127_8426158_5 Radical SAM superfamily K22226 - - 0.00000000000000000000000000000000000000000000001095 185.0
TLS3_k127_8426158_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000009762 92.0
TLS3_k127_8426158_7 - - - - 0.000000000000003136 88.0
TLS3_k127_8429775_0 Glyco_18 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 474.0
TLS3_k127_8429775_1 Bacterial transglutaminase-like N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 390.0
TLS3_k127_8429775_2 Circularly permuted ATP-grasp type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003689 241.0
TLS3_k127_8429775_3 deacetylase - - - 0.00000000000000000000000000000000000000000000000000007103 209.0
TLS3_k127_8429775_4 - - - - 0.000000000000000000000000000000000000000000039 171.0
TLS3_k127_8429775_5 chitinase K01183 - 3.2.1.14 0.000000000000000000000000000000000006608 155.0
TLS3_k127_8441909_0 repeat protein - - - 0.0 2497.0
TLS3_k127_8441909_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1499.0
TLS3_k127_8441909_2 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 458.0
TLS3_k127_8441909_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 443.0
TLS3_k127_8441909_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 356.0
TLS3_k127_8441909_5 Transcriptional Regulator, AraC family - - - 0.00000000000000000000000000000000000000000000000000000001077 214.0
TLS3_k127_8441909_6 Glycosyl hydrolases family 25 K07273 - - 0.00000000000000000000000000000000000000000000000006673 192.0
TLS3_k127_8441909_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000000000000000000000000000000002677 139.0
TLS3_k127_8446314_0 ABC-type transport system involved in lipoprotein release permease component K09808 - - 1.787e-225 711.0
TLS3_k127_8446314_1 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 2.304e-198 651.0
TLS3_k127_8446314_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 509.0
TLS3_k127_8446314_4 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 447.0
TLS3_k127_8446314_7 amino acid activation for nonribosomal peptide biosynthetic process K20951 - - 0.000000000000000000000000000000000000000000000000000000000000113 235.0
TLS3_k127_8447032_0 AAA ATPase domain - - - 0.0 1155.0
TLS3_k127_8447032_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1091.0
TLS3_k127_8447032_11 protein conserved in bacteria - - - 0.000000000000000000000000005248 114.0
TLS3_k127_8447032_2 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 526.0
TLS3_k127_8447032_3 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 498.0
TLS3_k127_8447032_4 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 426.0
TLS3_k127_8447032_5 Belongs to the LDH MDH superfamily K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 425.0
TLS3_k127_8447032_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 322.0
TLS3_k127_8447032_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001164 269.0
TLS3_k127_8447032_9 guanyl-nucleotide exchange factor activity K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000007952 234.0
TLS3_k127_8457796_0 nuclear chromosome segregation - - - 4.95e-224 712.0
TLS3_k127_8457796_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 562.0
TLS3_k127_8457796_2 Von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000003604 194.0
TLS3_k127_8481213_0 Involved in the tonB-independent uptake of proteins - - - 1.943e-237 750.0
TLS3_k127_8481213_1 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 436.0
TLS3_k127_8481213_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 432.0
TLS3_k127_8481213_3 Protein of unknown function (DUF2804) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 353.0
TLS3_k127_8481213_4 OmpA family K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003878 297.0
TLS3_k127_8481213_5 DNA primase activity - - - 0.00000000000000000000000000000000000000000000000000002864 194.0
TLS3_k127_8481213_6 Belongs to the peptidase S8 family - - - 0.0000000000000000001271 105.0
TLS3_k127_8501039_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 2.41e-213 670.0
TLS3_k127_8501039_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 479.0
TLS3_k127_8501039_2 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 471.0
TLS3_k127_8501039_3 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 438.0
TLS3_k127_8501039_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000004059 169.0
TLS3_k127_8507104_0 Bacterial regulatory protein, Fis family - - - 9.572e-230 732.0
TLS3_k127_8507104_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 2.393e-197 630.0
TLS3_k127_8507104_2 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 547.0
TLS3_k127_8507104_3 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008408 253.0
TLS3_k127_8516688_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 2.214e-217 707.0
TLS3_k127_8516688_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 334.0
TLS3_k127_8516688_10 Stigma-specific protein, Stig1 - - - 0.000000000000000001686 98.0
TLS3_k127_8516688_12 - - - - 0.00001702 55.0
TLS3_k127_8516688_2 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 326.0
TLS3_k127_8516688_3 lipopolysaccharide transmembrane transporter activity K06178,K07058 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000005548 257.0
TLS3_k127_8516688_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004679 241.0
TLS3_k127_8516688_5 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000004059 165.0
TLS3_k127_8516688_9 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000004704 99.0
TLS3_k127_8519439_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0 1069.0
TLS3_k127_8519439_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 5.061e-212 669.0
TLS3_k127_8519439_10 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 352.0
TLS3_k127_8519439_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001223 286.0
TLS3_k127_8519439_14 Protein of unknown function (DUF507) K09804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002911 245.0
TLS3_k127_8519439_15 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000174 235.0
TLS3_k127_8519439_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000348 219.0
TLS3_k127_8519439_17 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000474 201.0
TLS3_k127_8519439_18 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000005105 163.0
TLS3_k127_8519439_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 600.0
TLS3_k127_8519439_3 Polysaccharide biosynthesis protein K01784,K02473 - 5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 539.0
TLS3_k127_8519439_4 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 509.0
TLS3_k127_8519439_5 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 476.0
TLS3_k127_8519439_6 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 454.0
TLS3_k127_8519439_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 417.0
TLS3_k127_8519439_8 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 365.0
TLS3_k127_8519439_9 Family membership K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 370.0
TLS3_k127_8535242_0 Male sterility protein K01897 - 6.2.1.3 0.0 2240.0
TLS3_k127_8535242_1 protein conserved in bacteria K11904 - - 8.755e-272 842.0
TLS3_k127_8535242_10 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001415 250.0
TLS3_k127_8535242_11 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000000000000000000000000003371 228.0
TLS3_k127_8535242_12 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000002191 228.0
TLS3_k127_8535242_13 Helix-hairpin-helix motif K02237 - - 0.000000000000000000000000000005448 126.0
TLS3_k127_8535242_2 Uncharacterized protein conserved in bacteria (DUF2169) - - - 2.5e-212 685.0
TLS3_k127_8535242_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 545.0
TLS3_k127_8535242_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 541.0
TLS3_k127_8535242_5 epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 478.0
TLS3_k127_8535242_6 amino acid ABC transporter, ATP-binding protein K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 423.0
TLS3_k127_8535242_7 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 400.0
TLS3_k127_8535242_8 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 384.0
TLS3_k127_8539414_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 553.0
TLS3_k127_8539414_1 pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 454.0
TLS3_k127_8539414_2 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001922 239.0
TLS3_k127_8539414_3 protein containing caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002991 242.0
TLS3_k127_8562861_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 3.656e-237 740.0
TLS3_k127_8562861_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 495.0
TLS3_k127_8562861_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 472.0
TLS3_k127_8562861_3 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 474.0
TLS3_k127_8562861_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000135 215.0
TLS3_k127_8562861_5 - - - - 0.000000000000000000000000000000000001239 151.0
TLS3_k127_8562861_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000002397 106.0
TLS3_k127_8570742_0 Polysaccharide biosynthesis protein CapD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 549.0
TLS3_k127_8570742_1 symbiont process K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 463.0
TLS3_k127_8570742_10 Spore maturation protein cgeB K06320 - - 0.00000000000000133 90.0
TLS3_k127_8570742_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 353.0
TLS3_k127_8570742_3 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006735 285.0
TLS3_k127_8570742_4 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000002537 252.0
TLS3_k127_8570742_5 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000001043 174.0
TLS3_k127_8570742_6 PFAM Glycosyl transferase family 4 K13007 - - 0.000000000000000000000000000000000000000003176 169.0
TLS3_k127_8570742_7 Male sterility protein K19997 - 5.1.3.26 0.000000000000000000000008169 118.0
TLS3_k127_8570742_8 protein trimerization - - - 0.00000000000000000000004658 104.0
TLS3_k127_8570742_9 Glycosyltransferase Family 4 - - - 0.000000000000000000005669 106.0
TLS3_k127_85955_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 4.762e-303 944.0
TLS3_k127_85955_1 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 556.0
TLS3_k127_85955_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 525.0
TLS3_k127_85955_3 Zinc-binding dehydrogenase K13953,K13979 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009101 454.0
TLS3_k127_85955_4 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 295.0
TLS3_k127_85955_5 Belongs to the cytochrome P450 family - - - 0.00000000000000000000000000000000000000000000000000000000000001106 234.0
TLS3_k127_85955_6 Transcriptional regulator, Fis family - - - 0.00000000125 64.0
TLS3_k127_85955_7 WD40 repeats - - - 0.000000002079 68.0
TLS3_k127_864837_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.132e-314 968.0
TLS3_k127_864837_1 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 448.0
TLS3_k127_864837_2 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 438.0
TLS3_k127_864837_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 283.0
TLS3_k127_864837_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004112 261.0
TLS3_k127_864837_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004509 244.0
TLS3_k127_864837_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002242 228.0
TLS3_k127_864837_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000000000001744 175.0
TLS3_k127_864837_8 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000001797 170.0
TLS3_k127_866327_0 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 0.0 1024.0
TLS3_k127_866327_1 Transglycosylase SLT domain K08309 - - 6.723e-216 701.0
TLS3_k127_866327_11 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001133 259.0
TLS3_k127_866327_12 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000001299 190.0
TLS3_k127_866327_15 acid phosphatase activity K03651 - 3.1.4.53 0.000000000002335 76.0
TLS3_k127_866327_16 phospho-2-dehydro-3-deoxyheptonate aldolase - - - 0.0000000007514 67.0
TLS3_k127_866327_18 - - - - 0.00000386 51.0
TLS3_k127_866327_19 Transglycosylase SLT domain K08309 - - 0.000009263 48.0
TLS3_k127_866327_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 563.0
TLS3_k127_866327_4 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 536.0
TLS3_k127_866327_5 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 474.0
TLS3_k127_866327_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 465.0
TLS3_k127_866327_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 467.0
TLS3_k127_866327_8 COG0471 Di- and tricarboxylate K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 416.0
TLS3_k127_866327_9 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 391.0
TLS3_k127_867208_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 571.0
TLS3_k127_867208_1 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 526.0
TLS3_k127_867208_2 Vacuolar protein sorting-associated protein 62 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 331.0
TLS3_k127_867208_3 PEGA domain - - - 0.00000000000000000000000000000000000000000000000000000000000763 235.0
TLS3_k127_867208_4 Dual-action HEIGH metallo-peptidase - - - 0.00000000000000000000000008129 122.0
TLS3_k127_867208_5 - - - - 0.00000000000000000001153 107.0
TLS3_k127_870669_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 562.0
TLS3_k127_870669_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 400.0
TLS3_k127_870669_2 deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007469 277.0
TLS3_k127_870669_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000009433 157.0
TLS3_k127_870669_4 HNH endonuclease - - - 0.0000000000000000000000000000000003446 136.0
TLS3_k127_880132_0 FAD binding domain - - - 9.849e-260 812.0
TLS3_k127_880132_1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 5.629e-242 762.0
TLS3_k127_880132_10 phosphatase activity K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003253 270.0
TLS3_k127_880132_12 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000000001808 216.0
TLS3_k127_880132_14 Putative restriction endonuclease - - - 0.000000002478 65.0
TLS3_k127_880132_15 COG3436 Transposase and inactivated derivatives - - - 0.000001775 51.0
TLS3_k127_880132_16 - - - - 0.0001612 50.0
TLS3_k127_880132_17 Putative restriction endonuclease - - - 0.0007783 46.0
TLS3_k127_880132_2 Retinal pigment epithelial membrane protein K11159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 523.0
TLS3_k127_880132_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 504.0
TLS3_k127_880132_4 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 477.0
TLS3_k127_880132_5 Hsp70 protein K04046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 426.0
TLS3_k127_880132_6 cell adhesion K02024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 381.0
TLS3_k127_880132_7 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 321.0
TLS3_k127_880132_8 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 317.0
TLS3_k127_880132_9 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 301.0
TLS3_k127_922599_0 4Fe-4S dicluster domain K00184 - - 0.0 1314.0
TLS3_k127_922599_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.748e-236 745.0
TLS3_k127_922599_10 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 351.0
TLS3_k127_922599_11 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 289.0
TLS3_k127_922599_12 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 297.0
TLS3_k127_922599_13 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001051 258.0
TLS3_k127_922599_14 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001328 247.0
TLS3_k127_922599_15 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004303 244.0
TLS3_k127_922599_16 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000000000000000000000000000000000000001338 184.0
TLS3_k127_922599_17 Domain of unknown function (DUF4833) - - - 0.00000000000000000002054 99.0
TLS3_k127_922599_19 Psort location CytoplasmicMembrane, score - - - 0.000000009663 65.0
TLS3_k127_922599_2 Polysulphide reductase, NrfD K00185 - - 4.841e-236 750.0
TLS3_k127_922599_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 544.0
TLS3_k127_922599_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 535.0
TLS3_k127_922599_5 synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 509.0
TLS3_k127_922599_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 449.0
TLS3_k127_922599_7 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 420.0
TLS3_k127_922599_8 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 348.0
TLS3_k127_922599_9 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 344.0
TLS3_k127_936397_0 Cytosol aminopeptidase family, catalytic domain K01255 - 3.4.11.1 2.83e-202 641.0
TLS3_k127_936397_1 ATP-grasp domain - - - 5.459e-198 623.0
TLS3_k127_936397_2 Putative esterase - - - 0.0000000000000000000000000000000000000000002078 164.0
TLS3_k127_936397_4 STAS domain K17763 - - 0.0000000000000000000000000000000004826 140.0
TLS3_k127_936397_5 cytochrome C peroxidase - - - 0.0000000000000000009803 101.0
TLS3_k127_936397_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000005393 74.0
TLS3_k127_941716_0 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 556.0
TLS3_k127_941716_1 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 475.0
TLS3_k127_941716_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000006115 223.0
TLS3_k127_941716_12 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000008029 207.0
TLS3_k127_941716_13 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000003202 202.0
TLS3_k127_941716_14 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000001409 192.0
TLS3_k127_941716_15 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000009423 163.0
TLS3_k127_941716_16 Transglycosylase associated protein - - - 0.000000000000000000000000000000002594 133.0
TLS3_k127_941716_17 cheY-homologous receiver domain - - - 0.00000000000000000000000000005784 119.0
TLS3_k127_941716_18 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.000000000000000000000000007355 127.0
TLS3_k127_941716_2 Two component transcriptional regulator, winged helix family K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 391.0
TLS3_k127_941716_20 serine-type endopeptidase activity K07114 - - 0.000000000000000000005544 108.0
TLS3_k127_941716_21 regulation of circadian rhythm K08482 - - 0.000000000000000000007178 107.0
TLS3_k127_941716_23 Serine/threonine phosphatases, family 2C, catalytic domain K01090 - 3.1.3.16 0.00000000000000000002318 105.0
TLS3_k127_941716_25 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.000000803 60.0
TLS3_k127_941716_3 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 377.0
TLS3_k127_941716_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 345.0
TLS3_k127_941716_5 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 300.0
TLS3_k127_941716_6 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016491,GO:0016614,GO:0018130,GO:0019438,GO:0019748,GO:0042469,GO:0043385,GO:0043386,GO:0044237,GO:0044249,GO:0044550,GO:0045460,GO:0045461,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901376,GO:1901378,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005988 280.0
TLS3_k127_941716_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000003521 247.0
TLS3_k127_941716_8 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000001684 217.0
TLS3_k127_941716_9 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000001468 228.0
TLS3_k127_965784_0 protein conserved in bacteria - - - 0.0 1130.0
TLS3_k127_965784_1 protein conserved in bacteria K11904 - - 7.792e-241 754.0
TLS3_k127_965784_11 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002127 253.0
TLS3_k127_965784_13 PAAR motif - - - 0.0000000000000000000000000000000000000000000000000002343 188.0
TLS3_k127_965784_14 - - - - 0.0000000000000000000000000000000000000000000001905 171.0
TLS3_k127_965784_18 - - - - 0.000000000000000000000005686 113.0
TLS3_k127_965784_19 double-stranded DNA endodeoxyribonuclease activity K02411 - - 0.0000000000000000000000219 106.0
TLS3_k127_965784_2 Belongs to the LarC family K09121 - 4.99.1.12 2.934e-212 709.0
TLS3_k127_965784_20 - - - - 0.000000000000000003153 93.0
TLS3_k127_965784_3 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 443.0
TLS3_k127_965784_4 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 388.0
TLS3_k127_965784_5 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 340.0
TLS3_k127_965784_6 belongs to the thioredoxin family K03671,K05838,K07390,K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 335.0
TLS3_k127_965784_7 Domain of unknown function (DUF4123) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 321.0
TLS3_k127_965784_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 296.0
TLS3_k127_965784_9 serine-type endopeptidase activity K07261,K17733,K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005135 280.0
TLS3_k127_97166_0 TonB dependent receptor K02014 - - 0.0 1028.0
TLS3_k127_97166_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 2.155e-271 842.0
TLS3_k127_97166_10 guanyl-nucleotide exchange factor activity K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003259 261.0
TLS3_k127_97166_11 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004852 244.0
TLS3_k127_97166_12 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000001494 237.0
TLS3_k127_97166_13 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000000002422 161.0
TLS3_k127_97166_15 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000292 142.0
TLS3_k127_97166_16 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.000000000000000000000000000005902 124.0
TLS3_k127_97166_17 - - - - 0.000000000000000000000000001303 118.0
TLS3_k127_97166_19 bromo domain - - - 0.0000000172 64.0
TLS3_k127_97166_2 cell adhesion involved in biofilm formation - - - 5.267e-230 737.0
TLS3_k127_97166_20 DNA integration - - - 0.00003648 51.0
TLS3_k127_97166_3 Amidohydrolase family K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 549.0
TLS3_k127_97166_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 527.0
TLS3_k127_97166_5 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 522.0
TLS3_k127_97166_6 Glutamate decarboxylase and related PLP-dependent proteins K13745,K18933 - 4.1.1.11,4.1.1.25,4.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 507.0
TLS3_k127_97166_7 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 402.0
TLS3_k127_97166_8 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 347.0
TLS3_k127_97166_9 depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 304.0
TLS3_k127_982397_0 Acyl transferase domain in polyketide synthase (PKS) enzymes. K04786 - - 0.0 2370.0
TLS3_k127_982397_1 non-ribosomal peptide synthetase - - - 3.156e-309 1007.0
TLS3_k127_982397_2 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 573.0
TLS3_k127_982397_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000002461 121.0
TLS3_k127_988648_0 Glycosyl hydrolase family 46 K01233 - 3.2.1.132 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 560.0
TLS3_k127_988648_1 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 444.0
TLS3_k127_988648_2 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 329.0
TLS3_k127_988648_3 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 323.0
TLS3_k127_988648_4 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001113 284.0
TLS3_k127_988648_6 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000007253 163.0
TLS3_k127_988648_7 amine dehydrogenase activity - - - 0.00000000000000000000000000001496 133.0
TLS3_k127_989134_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1488.0
TLS3_k127_989134_1 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 3.065e-247 770.0
TLS3_k127_989134_10 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 306.0
TLS3_k127_989134_11 C2 domain K06399 - 3.4.21.116 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 290.0
TLS3_k127_989134_12 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000005613 233.0
TLS3_k127_989134_13 small periplasmic lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000004541 222.0
TLS3_k127_989134_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 481.0
TLS3_k127_989134_3 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 437.0
TLS3_k127_989134_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 406.0
TLS3_k127_989134_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 337.0
TLS3_k127_989134_6 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 338.0
TLS3_k127_989134_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 329.0
TLS3_k127_989134_8 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 326.0
TLS3_k127_989134_9 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 305.0
TLS3_k127_990482_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.847e-310 960.0
TLS3_k127_990482_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 455.0
TLS3_k127_990482_2 Protoglobin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 387.0
TLS3_k127_990482_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000003643 168.0
TLS3_k127_995633_0 B12 binding domain - - - 1.914e-300 936.0
TLS3_k127_995633_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 475.0
TLS3_k127_995633_2 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 374.0
TLS3_k127_995633_3 B3/4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 292.0
TLS3_k127_995633_4 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000005521 220.0