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Overview

ID MAG04066
Name TLS3_bin.7
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Nitrospiria
Order Nitrospirales
Family Nitrospiraceae
Genus Nitrospira_D
Species Nitrospira_D sp041742455
Assembly information
Completeness (%) 83.82
Contamination (%) 5.15
GC content (%) 54.0
N50 (bp) 7,580
Genome size (bp) 3,446,078

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3185

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1003043_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 2.556e-251 777.0
TLS3_k127_1003043_1 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 548.0
TLS3_k127_1003043_10 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000000000000000002911 106.0
TLS3_k127_1003043_2 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 482.0
TLS3_k127_1003043_3 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 469.0
TLS3_k127_1003043_4 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000006603 248.0
TLS3_k127_1003043_5 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000007641 207.0
TLS3_k127_1003043_7 ThiS family K03636 - - 0.000000000000000000000000000000000000000006501 154.0
TLS3_k127_1003043_8 NIL - - - 0.00000000000000000000000000000000009124 134.0
TLS3_k127_1008349_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 468.0
TLS3_k127_1008349_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 459.0
TLS3_k127_1008349_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 291.0
TLS3_k127_1008349_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005262 278.0
TLS3_k127_1008349_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000001598 177.0
TLS3_k127_1008349_5 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000002719 161.0
TLS3_k127_1008349_6 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000000000000000000001103 112.0
TLS3_k127_1020755_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 8.4e-323 992.0
TLS3_k127_1020755_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 434.0
TLS3_k127_1020755_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 356.0
TLS3_k127_1020755_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 294.0
TLS3_k127_1020755_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000007656 263.0
TLS3_k127_1020755_5 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000000000000000000000001265 175.0
TLS3_k127_1020755_6 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000000000000000000000000000000006105 142.0
TLS3_k127_1025637_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 2.475e-237 736.0
TLS3_k127_1025637_1 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 526.0
TLS3_k127_1025637_2 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 504.0
TLS3_k127_105013_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.533e-294 909.0
TLS3_k127_105013_1 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000004308 177.0
TLS3_k127_105013_2 bacterial (prokaryotic) histone like domain K04764 - - 0.0000000000000000000000000000000000000000000001169 168.0
TLS3_k127_1065122_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 9.13e-277 856.0
TLS3_k127_1065122_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000004062 210.0
TLS3_k127_1065122_3 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000016 168.0
TLS3_k127_1065122_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000007067 163.0
TLS3_k127_1065122_5 response regulator - - - 0.00000000000000000000000006286 111.0
TLS3_k127_1065122_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000002785 61.0
TLS3_k127_1069672_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 490.0
TLS3_k127_1069672_1 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000001068 152.0
TLS3_k127_1077055_0 PFAM RNA-directed DNA polymerase (reverse transcriptase) - - - 1.744e-230 720.0
TLS3_k127_1077055_2 SnoaL-like domain - - - 0.00000002654 56.0
TLS3_k127_1077055_3 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00001123 50.0
TLS3_k127_1086850_0 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 419.0
TLS3_k127_1086850_1 Malate/L-lactate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 292.0
TLS3_k127_1086850_2 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.000000000000000000000004382 114.0
TLS3_k127_1097517_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2537.0
TLS3_k127_1097517_1 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1618.0
TLS3_k127_1097517_10 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000001002 84.0
TLS3_k127_1097517_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1273.0
TLS3_k127_1097517_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 471.0
TLS3_k127_1097517_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 400.0
TLS3_k127_1097517_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 318.0
TLS3_k127_1097517_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001221 250.0
TLS3_k127_1097517_7 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001591 237.0
TLS3_k127_1097517_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000002552 220.0
TLS3_k127_1097517_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000008526 83.0
TLS3_k127_1098238_0 radical SAM domain protein K04034 - 1.21.98.3 3.189e-265 823.0
TLS3_k127_1098238_1 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000000006175 123.0
TLS3_k127_11073_0 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 596.0
TLS3_k127_11073_1 FliG middle domain K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 443.0
TLS3_k127_11073_2 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000002297 241.0
TLS3_k127_11073_3 PFAM MgtE intracellular K02383 - - 0.0000000000000000000000000000346 126.0
TLS3_k127_11073_4 phosphorelay signal transduction system K10941 - - 0.000000000000000000000002883 115.0
TLS3_k127_1113480_0 phosphorelay sensor kinase activity K02668 - 2.7.13.3 8.21e-247 774.0
TLS3_k127_1113480_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 5.034e-195 616.0
TLS3_k127_1113480_2 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 462.0
TLS3_k127_1113480_3 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000001003 160.0
TLS3_k127_1117842_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 506.0
TLS3_k127_1117842_1 biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 456.0
TLS3_k127_1117842_2 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 302.0
TLS3_k127_1117842_3 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 300.0
TLS3_k127_1117842_4 - - - - 0.00000000000000000000000000000000000000000000001675 177.0
TLS3_k127_1117842_5 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000004724 170.0
TLS3_k127_1117842_6 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000002516 175.0
TLS3_k127_1117842_7 - - - - 0.000000000000000000000000224 111.0
TLS3_k127_1117842_8 pyrroloquinoline quinone biosynthesis protein D K06138 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.000000002534 63.0
TLS3_k127_112877_0 AAA domain - - - 1.51e-198 650.0
TLS3_k127_112877_1 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000004864 140.0
TLS3_k127_112877_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000003869 110.0
TLS3_k127_112877_3 Domain of unknown function (DUF4258) - - - 0.000000000000000001665 89.0
TLS3_k127_112877_4 - - - - 0.000002774 52.0
TLS3_k127_112877_5 DNA integration - - - 0.0008316 44.0
TLS3_k127_1132169_0 PFAM 20S proteasome, A and B subunits K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 332.0
TLS3_k127_1132169_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005158 245.0
TLS3_k127_1135633_0 - - - - 0.000000000000000000000000000000000000002671 152.0
TLS3_k127_1135633_1 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000002917 146.0
TLS3_k127_1135633_2 HEAT repeats - - - 0.0000000000000000000000000000000005634 141.0
TLS3_k127_1135633_3 sequence-specific DNA binding - - - 0.000000000000000000000001741 105.0
TLS3_k127_1135633_4 COG3209 Rhs family protein - - - 0.000000000000000000005325 103.0
TLS3_k127_1135633_5 sequence-specific DNA binding - - - 0.000000000000000115 82.0
TLS3_k127_1135633_6 TIGRFAM RHS repeat-associated core domain-containing protein - - - 0.000000000005254 76.0
TLS3_k127_1135633_7 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.0004488 47.0
TLS3_k127_1141304_0 mismatched DNA binding K03555 - - 6.327e-200 640.0
TLS3_k127_1141304_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 316.0
TLS3_k127_1141304_2 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002297 270.0
TLS3_k127_1141304_3 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000005038 220.0
TLS3_k127_1142451_0 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 473.0
TLS3_k127_1142451_1 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 407.0
TLS3_k127_1142451_10 DNA excision K02806 - - 0.00000000000000000000000001027 111.0
TLS3_k127_1142451_11 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000007023 120.0
TLS3_k127_1142451_12 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000004947 100.0
TLS3_k127_1142451_13 flagellar protein FlaG K06603 - - 0.0000000000000000001033 93.0
TLS3_k127_1142451_15 transmembrane signaling receptor activity K03406 - - 0.0000007814 57.0
TLS3_k127_1142451_2 bacterial-type flagellum organization K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 389.0
TLS3_k127_1142451_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 366.0
TLS3_k127_1142451_4 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 296.0
TLS3_k127_1142451_5 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000001943 210.0
TLS3_k127_1142451_7 Chemotaxis phosphatase, CheZ K03414 - - 0.00000000000000000000000000000000000000003914 159.0
TLS3_k127_1142451_8 Flagellar protein FliS K02422 - - 0.00000000000000000000000000000000000002038 148.0
TLS3_k127_1150927_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 354.0
TLS3_k127_1150927_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 331.0
TLS3_k127_1150927_3 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000000000132 156.0
TLS3_k127_1152977_0 phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 524.0
TLS3_k127_1152977_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 0.00000000000001066 76.0
TLS3_k127_1154129_0 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000447 257.0
TLS3_k127_1154129_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000001973 208.0
TLS3_k127_1154129_2 transporter K07238,K11021,K16267 - - 0.000000000000000000000000000000000000000000000000000003228 197.0
TLS3_k127_1154129_3 IMP dehydrogenase activity K09137 - - 0.0000000000000000000000000000000000000000004582 162.0
TLS3_k127_1154129_4 ATP-independent chaperone mediated protein folding - - - 0.0000000000000000000000000000003885 131.0
TLS3_k127_1154129_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.0000000000000000000000001182 110.0
TLS3_k127_1154129_7 cation diffusion facilitator family transporter - - - 0.00000004551 55.0
TLS3_k127_1154129_8 YtxH-like protein - - - 0.000000303 57.0
TLS3_k127_1154129_9 DnaK suppressor protein - - - 0.00002639 50.0
TLS3_k127_1181080_0 Protein involved in outer membrane biogenesis K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 605.0
TLS3_k127_1181080_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 415.0
TLS3_k127_1181080_2 Mur ligase middle domain protein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 344.0
TLS3_k127_1181080_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000001716 192.0
TLS3_k127_1181080_4 peptidase K02557,K21471 - - 0.00000000000000000000000000000000000000000000005699 181.0
TLS3_k127_1181080_5 Transcriptional regulator K12146,K15836 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.00000000131 66.0
TLS3_k127_1181080_6 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0006055 49.0
TLS3_k127_1199953_0 PFAM Peptidase family M48 - - - 0.000000000002894 76.0
TLS3_k127_1199953_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0002207 45.0
TLS3_k127_1241839_0 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 385.0
TLS3_k127_1241839_1 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 284.0
TLS3_k127_1241839_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006892 237.0
TLS3_k127_1241839_3 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001876 235.0
TLS3_k127_1241839_4 - - - - 0.000000000000000000000000000000000000000000000000000000000001711 215.0
TLS3_k127_1241839_5 - - - - 0.0000000000000000000000000000000000000000003139 165.0
TLS3_k127_1241839_6 PFAM Copper resistance protein CopC K07156 - - 0.000000000000000000000000000000000000000005342 158.0
TLS3_k127_1241839_7 DDE superfamily endonuclease K07494 - - 0.000000000000000000000000000000000003223 139.0
TLS3_k127_1241839_8 PFAM Copper resistance D K07245 - - 0.0000000000000000003475 90.0
TLS3_k127_1241839_9 electron transfer activity K00428 - 1.11.1.5 0.00000008048 57.0
TLS3_k127_1242092_0 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1115.0
TLS3_k127_1242092_1 - - - - 0.00000000000000000000000000000000000000000000000000000002489 200.0
TLS3_k127_1260497_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1185.0
TLS3_k127_1260497_1 Heat shock 70 kDa protein K04043 - - 0.0 1114.0
TLS3_k127_1260497_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 338.0
TLS3_k127_1260497_3 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 306.0
TLS3_k127_1260497_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000000000001634 218.0
TLS3_k127_1260497_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000003603 211.0
TLS3_k127_1260497_6 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000004893 214.0
TLS3_k127_1269878_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 295.0
TLS3_k127_1269878_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001211 262.0
TLS3_k127_1269878_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000006931 246.0
TLS3_k127_1269878_3 Alpha/beta hydrolase family - - - 0.00004913 47.0
TLS3_k127_1269878_4 Cache domain - - - 0.0006591 45.0
TLS3_k127_1288523_1 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000001347 202.0
TLS3_k127_1313631_0 Protein of unknown function, DUF255 K06888 - - 0.0 1529.0
TLS3_k127_1313631_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 1.384e-213 674.0
TLS3_k127_1313631_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 550.0
TLS3_k127_1313631_3 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001302 280.0
TLS3_k127_1313631_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000195 232.0
TLS3_k127_1313631_5 peptidyl-tyrosine sulfation K02450 - - 0.00000000000000000000000000000000000000000000000000000000001354 217.0
TLS3_k127_1313631_6 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000001368 147.0
TLS3_k127_1313631_7 peptidyl-tyrosine sulfation K02450 - - 0.0000000000000000000000000000000000147 139.0
TLS3_k127_1326236_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001373 239.0
TLS3_k127_1326236_3 reverse transcriptase - - - 0.0005787 45.0
TLS3_k127_134704_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1262.0
TLS3_k127_134704_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 2.683e-321 989.0
TLS3_k127_134704_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000131 208.0
TLS3_k127_134704_11 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000006286 200.0
TLS3_k127_134704_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000003511 145.0
TLS3_k127_134704_13 Fic/DOC family K07341 - - 0.0000000000000000000000000000003505 126.0
TLS3_k127_134704_14 TonB-dependent Receptor Plug Domain K02014 - - 0.000000000000000000000005637 104.0
TLS3_k127_134704_15 PFAM SpoVT AbrB K07172,K18842 - - 0.0000000000003154 74.0
TLS3_k127_134704_2 NADH-quinone oxidoreductase K00341 - 1.6.5.3 3.161e-316 978.0
TLS3_k127_134704_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.048e-249 774.0
TLS3_k127_134704_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 589.0
TLS3_k127_134704_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 497.0
TLS3_k127_134704_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 475.0
TLS3_k127_134704_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009254 359.0
TLS3_k127_134704_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 306.0
TLS3_k127_134704_9 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 300.0
TLS3_k127_1362677_0 alanine dehydrogenase activity K00259 GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 538.0
TLS3_k127_1362677_1 Response regulator, receiver K20973 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 534.0
TLS3_k127_1362677_10 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000004241 193.0
TLS3_k127_1362677_11 Ferredoxin - - - 0.0000000000000000000000000000000000000000000004251 168.0
TLS3_k127_1362677_12 - - - - 0.000000000000000000000000000000000000000003969 161.0
TLS3_k127_1362677_13 - - - - 0.0000000000000000000000000000000002682 138.0
TLS3_k127_1362677_15 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000000000000000004757 95.0
TLS3_k127_1362677_16 - - - - 0.0000299 48.0
TLS3_k127_1362677_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 512.0
TLS3_k127_1362677_3 Squalene/phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 456.0
TLS3_k127_1362677_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 445.0
TLS3_k127_1362677_5 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 431.0
TLS3_k127_1362677_6 response regulator, receiver K03413,K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 294.0
TLS3_k127_1362677_8 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000001695 216.0
TLS3_k127_1362677_9 - - - - 0.00000000000000000000000000000000000000000000000000000002853 197.0
TLS3_k127_1382232_0 transferase activity, transferring hexosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 386.0
TLS3_k127_1382232_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000001835 173.0
TLS3_k127_1382232_3 ubiE/COQ5 methyltransferase family - - - 0.0000259 51.0
TLS3_k127_1422703_1 transposition K07497 - - 0.000000000000000000000000000000000000000000000000000001717 194.0
TLS3_k127_1422703_2 DNA repair - - - 0.000000000000000000000000000000000000000000000000006277 186.0
TLS3_k127_1422703_3 Sulfurtransferase TusA - - - 0.0000000000000000000000000004236 115.0
TLS3_k127_1422703_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000004397 108.0
TLS3_k127_1422703_5 transposition K07497 - - 0.0000000000000000000005179 100.0
TLS3_k127_1422703_6 DNA polymerase - - - 0.0000000000002612 71.0
TLS3_k127_1422703_7 transposition K07497 - - 0.00000000006855 69.0
TLS3_k127_1422703_8 - - - - 0.00000003111 57.0
TLS3_k127_1430160_0 DEAD-like helicase, N-terminal - - - 0.0 1337.0
TLS3_k127_1430160_1 Adenine specific DNA methylase Mod K07316 - 2.1.1.72 8.392e-214 703.0
TLS3_k127_1430160_10 WYL domain K13572 - - 0.000000835 50.0
TLS3_k127_1430160_2 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 1.088e-211 679.0
TLS3_k127_1430160_3 type I site-specific deoxyribonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000006372 236.0
TLS3_k127_1430160_4 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000000000000000000000000005486 194.0
TLS3_k127_1430160_5 - - - - 0.00000000000000000000000000000000000000000000001848 181.0
TLS3_k127_1430160_6 - - - - 0.0000000000000000000000000000000000000000007372 160.0
TLS3_k127_1430160_7 TIGRFAM YgiT-type zinc finger domain - - - 0.00000000000000000005189 91.0
TLS3_k127_1430160_8 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000184 60.0
TLS3_k127_1430160_9 - - - - 0.0000001271 55.0
TLS3_k127_1442565_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 436.0
TLS3_k127_1442565_1 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 422.0
TLS3_k127_1442565_2 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 346.0
TLS3_k127_1442565_3 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000001016 134.0
TLS3_k127_1442565_4 DNA excision K02806 - - 0.0000000000000000000000001553 110.0
TLS3_k127_1442565_5 - - - - 0.000000004335 58.0
TLS3_k127_1442809_0 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 506.0
TLS3_k127_1442809_1 peroxidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 437.0
TLS3_k127_1442809_2 NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 438.0
TLS3_k127_1442809_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000000000001665 219.0
TLS3_k127_1442809_5 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000007774 119.0
TLS3_k127_1442809_6 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.00000000000000000003302 98.0
TLS3_k127_1464975_0 Glycosyl hydrolase family 57 - - - 1.19e-321 998.0
TLS3_k127_1464975_1 phosphorelay signal transduction system - - - 1.947e-206 651.0
TLS3_k127_1464975_2 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 570.0
TLS3_k127_1464975_3 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 517.0
TLS3_k127_1464975_4 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 516.0
TLS3_k127_1464975_5 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 492.0
TLS3_k127_1464975_6 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 485.0
TLS3_k127_1464975_7 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 362.0
TLS3_k127_1464975_8 - - - - 0.0000000000000000000000000007772 117.0
TLS3_k127_1475614_0 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 440.0
TLS3_k127_1475614_1 Protein of unknown function (DUF2959) - - - 0.000000000000000000000000000000000000000000000000000000000001295 216.0
TLS3_k127_1475614_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.00000000000000000000000000000000005577 140.0
TLS3_k127_1510563_0 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001454 265.0
TLS3_k127_1510563_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004857 258.0
TLS3_k127_1563670_1 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004431 276.0
TLS3_k127_1563670_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000007612 143.0
TLS3_k127_1563670_5 Ribosomal protein L7/L12 C-terminal domain - - - 0.000000002488 62.0
TLS3_k127_156516_0 response regulator K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 589.0
TLS3_k127_156516_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000002159 189.0
TLS3_k127_159864_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 1.721e-271 842.0
TLS3_k127_159864_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000001234 145.0
TLS3_k127_159864_2 glutathione transferase activity K00799 - 2.5.1.18 0.0000000000145 69.0
TLS3_k127_1603010_0 glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000002135 207.0
TLS3_k127_1603010_1 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000008404 145.0
TLS3_k127_1603010_2 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000000001297 122.0
TLS3_k127_1603010_3 PFAM Glycosyl transferase family 2 K07011 - - 0.000000003282 66.0
TLS3_k127_1604310_0 transposition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 434.0
TLS3_k127_1604310_1 transposition - - - 0.00000000000000000000000000000002436 128.0
TLS3_k127_161774_0 twitching motility protein K02670 - - 3.595e-198 621.0
TLS3_k127_161774_2 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 339.0
TLS3_k127_161774_3 Dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000011 275.0
TLS3_k127_161774_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.0000000000000000000000000000000000000000000000000000009719 199.0
TLS3_k127_161774_5 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000007729 163.0
TLS3_k127_161774_6 Cytochrome c K00405 - - 0.000000000000000000000000000000000000000002175 161.0
TLS3_k127_161774_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.00000000000000000000000000001678 126.0
TLS3_k127_1620971_0 Ketoacyl-synthetase C-terminal extension - - - 0.0 1032.0
TLS3_k127_1620971_1 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 467.0
TLS3_k127_1624452_0 Monoamine oxidase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 538.0
TLS3_k127_1624452_1 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002488 235.0
TLS3_k127_1624452_2 5-oxoprolinase (ATP-hydrolyzing) activity K01457,K06351,K07160 - 3.5.1.54 0.000000000000000001656 90.0
TLS3_k127_1634736_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 617.0
TLS3_k127_1634736_1 GHMP kinase K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 361.0
TLS3_k127_1634736_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000002018 201.0
TLS3_k127_1634736_3 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.00000000000000000000000000009296 125.0
TLS3_k127_1635086_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 1.006e-267 844.0
TLS3_k127_1635086_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 391.0
TLS3_k127_1635086_2 Histidine kinase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001004 262.0
TLS3_k127_1635086_3 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000001386 201.0
TLS3_k127_1635086_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20974 - 2.7.13.3 0.00000000000000000000000000002886 123.0
TLS3_k127_1635086_5 ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000003176 85.0
TLS3_k127_1635086_6 Histidine kinase K07638 - 2.7.13.3 0.0000000000002371 71.0
TLS3_k127_1635086_8 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.000000001422 62.0
TLS3_k127_1635086_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00009787 45.0
TLS3_k127_1642784_0 PFAM Type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 489.0
TLS3_k127_1642784_1 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 347.0
TLS3_k127_1642784_2 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000155 180.0
TLS3_k127_1642784_3 Prokaryotic N-terminal methylation motif K02457 - - 0.00001879 54.0
TLS3_k127_1647570_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 354.0
TLS3_k127_1669292_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 1.671e-254 797.0
TLS3_k127_1669292_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 1.872e-208 663.0
TLS3_k127_1669292_10 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000009116 227.0
TLS3_k127_1669292_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00000000000000000000000000000000000000000000000000000000008519 213.0
TLS3_k127_1669292_12 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000000000000000004136 209.0
TLS3_k127_1669292_13 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.000000000000000000000000000000000000000000000000000000001709 214.0
TLS3_k127_1669292_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00000000000000000000000000000000000000000000121 171.0
TLS3_k127_1669292_15 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000007728 124.0
TLS3_k127_1669292_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 496.0
TLS3_k127_1669292_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 410.0
TLS3_k127_1669292_4 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 411.0
TLS3_k127_1669292_5 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 397.0
TLS3_k127_1669292_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 387.0
TLS3_k127_1669292_7 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 359.0
TLS3_k127_1669292_8 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000005974 274.0
TLS3_k127_1669292_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000001508 235.0
TLS3_k127_1684475_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.362e-267 827.0
TLS3_k127_1684475_1 peptidyl-serine autophosphorylation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004236 282.0
TLS3_k127_1684475_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006303 273.0
TLS3_k127_1684475_3 - - - - 0.00000000000000000000000000000000000000000000001024 175.0
TLS3_k127_1684475_4 iron dependent repressor K01356,K03709 - 3.4.21.88 0.0000000000000000000000000000000002695 134.0
TLS3_k127_1684475_5 nitric oxide dioxygenase activity - - - 0.0000000000000000000000005558 106.0
TLS3_k127_1684475_6 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000002565 58.0
TLS3_k127_1702128_0 MacB-like periplasmic core domain K02004 - - 5.253e-255 812.0
TLS3_k127_1702128_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 602.0
TLS3_k127_1702128_10 Protein of unknown function (DUF3703) - - - 0.00000000000000000000000000000000005827 136.0
TLS3_k127_1702128_11 Regulatory protein, FmdB family - - - 0.0000000000000000000000000002069 119.0
TLS3_k127_1702128_12 response regulator - - - 0.000000000000000000000005449 105.0
TLS3_k127_1702128_13 DNA excision K02806 - - 0.0000000001375 63.0
TLS3_k127_1702128_2 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 495.0
TLS3_k127_1702128_3 Evidence 2b Function of strongly homologous gene K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 347.0
TLS3_k127_1702128_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 346.0
TLS3_k127_1702128_5 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 294.0
TLS3_k127_1702128_6 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000677 270.0
TLS3_k127_1702128_7 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004259 248.0
TLS3_k127_1702128_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000004684 195.0
TLS3_k127_1702128_9 crossover junction endodeoxyribonuclease activity K01160 - 3.1.22.4 0.0000000000000000000000000000000000000000000004021 175.0
TLS3_k127_1714513_0 Transglutaminase/protease-like homologues - - - 3.184e-198 641.0
TLS3_k127_1714513_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 497.0
TLS3_k127_1714513_2 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 321.0
TLS3_k127_1714513_4 - - - - 0.00000005049 54.0
TLS3_k127_1725756_0 Phosphoenolpyruvate phosphomutase - - - 2.963e-196 621.0
TLS3_k127_1725756_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 560.0
TLS3_k127_1725756_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 363.0
TLS3_k127_1725756_3 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 325.0
TLS3_k127_1725756_4 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.0000000000000000000000000000000000000000000000000000000000007404 218.0
TLS3_k127_1725756_5 Methyltransferase type 11 - - - 0.000000111 63.0
TLS3_k127_176889_0 PFAM Alpha amylase K00700 - 2.4.1.18 1.829e-245 773.0
TLS3_k127_176889_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006416 256.0
TLS3_k127_176889_2 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000007604 192.0
TLS3_k127_176889_3 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.0000000000000000000000000004053 118.0
TLS3_k127_176889_4 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.00000000000000000006234 90.0
TLS3_k127_176889_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000001997 78.0
TLS3_k127_176889_6 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 0.000000000006664 68.0
TLS3_k127_176889_7 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.000003815 50.0
TLS3_k127_176889_8 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.0001172 44.0
TLS3_k127_176889_9 Peptidase family M48 K03799 - - 0.0008381 44.0
TLS3_k127_1777224_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 379.0
TLS3_k127_1777224_1 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000000005804 223.0
TLS3_k127_1777224_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000005143 167.0
TLS3_k127_1777224_4 YGGT family K02221 - - 0.00000000000000000000000000003538 120.0
TLS3_k127_179368_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.996e-247 771.0
TLS3_k127_179368_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 2.429e-246 767.0
TLS3_k127_179368_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.481e-240 747.0
TLS3_k127_179368_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000004625 240.0
TLS3_k127_179368_4 Bacterial protein of unknown function (DUF948) - - - 0.000000000000000000000000000000000000000000001751 168.0
TLS3_k127_179368_5 cell cycle K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.0000000000000000000006331 99.0
TLS3_k127_179368_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000006978 48.0
TLS3_k127_1794158_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0001254 46.0
TLS3_k127_1794158_1 OmpA family - - - 0.0002198 49.0
TLS3_k127_1798172_0 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003922 288.0
TLS3_k127_1798172_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000006324 220.0
TLS3_k127_1798172_2 HIT domain K02503 - - 0.000000000000000000000000000000005567 130.0
TLS3_k127_1798172_3 cytidyltransferase-related domain K00952 - 2.7.7.1 0.0000000000000000000000000000003531 131.0
TLS3_k127_1808143_0 Uncharacterized protein conserved in bacteria (DUF2330) K00347,K21163 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 8.761e-239 744.0
TLS3_k127_1808143_1 RNA secondary structure unwinding K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 601.0
TLS3_k127_1808143_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 475.0
TLS3_k127_1808143_3 Uncharacterized protein conserved in bacteria (DUF2330) K00347,K21163 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000003558 199.0
TLS3_k127_1808143_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000102 175.0
TLS3_k127_1808143_5 Belongs to the NqrB RnfD family - - - 0.00000000000000000000000000001393 126.0
TLS3_k127_1808143_7 - - - - 0.000000000000000004235 89.0
TLS3_k127_1808143_8 - - - - 0.00000587 57.0
TLS3_k127_1857991_0 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 612.0
TLS3_k127_1865231_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 522.0
TLS3_k127_1865231_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 295.0
TLS3_k127_1865231_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 291.0
TLS3_k127_1865231_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000001032 226.0
TLS3_k127_1865231_5 Cytochrome c - - - 0.000000000000000000000000000000000000000003308 160.0
TLS3_k127_1865231_6 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000004141 166.0
TLS3_k127_1865231_7 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000102 126.0
TLS3_k127_1865231_8 beta-lactamase activity K07126 - - 0.0000000000000000000000001891 114.0
TLS3_k127_188110_0 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 7.694e-300 926.0
TLS3_k127_188110_1 Alcohol dehydrogenase GroES-like domain K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 497.0
TLS3_k127_188110_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002752 222.0
TLS3_k127_188110_3 - - - - 0.000000000000000000000000000000000000002175 152.0
TLS3_k127_188110_4 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.000000000000002288 78.0
TLS3_k127_1885879_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 6.435e-254 785.0
TLS3_k127_1885879_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 586.0
TLS3_k127_1885879_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 486.0
TLS3_k127_1885879_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 436.0
TLS3_k127_1885879_4 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000292 217.0
TLS3_k127_1885879_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000003732 218.0
TLS3_k127_191877_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 376.0
TLS3_k127_191877_1 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 366.0
TLS3_k127_191877_2 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 317.0
TLS3_k127_191877_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000005427 172.0
TLS3_k127_191877_4 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000004314 167.0
TLS3_k127_1925224_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1146.0
TLS3_k127_1925224_1 metalloendopeptidase activity K08602 - - 2.298e-267 840.0
TLS3_k127_1925224_2 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 560.0
TLS3_k127_1925224_3 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000126 262.0
TLS3_k127_1925224_4 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000009838 171.0
TLS3_k127_1925224_7 2 iron, 2 sulfur cluster binding K02192 GO:0003674,GO:0005488,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.00000000000000001377 83.0
TLS3_k127_1931006_0 Bacterial regulatory protein, Fis family K13599 - - 1.258e-234 733.0
TLS3_k127_1931006_1 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000003113 240.0
TLS3_k127_1931475_0 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000002532 204.0
TLS3_k127_1931475_1 TPR repeat - - - 0.000000000000000000000000000000000000000000000003543 185.0
TLS3_k127_1951600_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.268e-201 637.0
TLS3_k127_1951600_1 Neutral trehalase Ca2+ binding domain K01194 GO:0001101,GO:0003674,GO:0003824,GO:0004553,GO:0004555,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009269,GO:0009311,GO:0009313,GO:0009414,GO:0009415,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0031668,GO:0033554,GO:0042221,GO:0042631,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0050896,GO:0051716,GO:0070887,GO:0071214,GO:0071229,GO:0071462,GO:0071465,GO:0071496,GO:0071704,GO:0104004,GO:1901575,GO:1901700,GO:1901701 3.2.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 619.0
TLS3_k127_1951600_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00008808 53.0
TLS3_k127_1951600_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001008 283.0
TLS3_k127_1951600_3 ATP synthase K02115 - - 0.00000000000000000000000000000000000000000000000000000843 201.0
TLS3_k127_1951600_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000002752 185.0
TLS3_k127_1951600_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000001792 128.0
TLS3_k127_1951600_6 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000000000000000000000000007224 119.0
TLS3_k127_1951600_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000001908 89.0
TLS3_k127_1951600_9 response regulator, receiver - - - 0.000000000837 64.0
TLS3_k127_1955182_0 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001102 265.0
TLS3_k127_1955182_1 AhpC/TSA family K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000003697 226.0
TLS3_k127_1955182_2 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000000000000000000001555 194.0
TLS3_k127_1955182_3 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000009214 198.0
TLS3_k127_1955182_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000002495 139.0
TLS3_k127_1955182_6 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000000003483 124.0
TLS3_k127_1955182_7 Protein of unknown function (DUF507) - - - 0.00000000000000000000007083 101.0
TLS3_k127_1961916_0 Transposase - - - 0.00000000000000000000000000000002552 138.0
TLS3_k127_1961916_1 - - - - 0.000002841 50.0
TLS3_k127_1966669_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 441.0
TLS3_k127_1966669_1 Domain of unknown function (DUF2341) - - - 0.000000000000000000000000009291 130.0
TLS3_k127_1966669_2 Domain of unknown function DUF11 - - - 0.000000000000000000000002996 121.0
TLS3_k127_1995834_0 AAA ATPase domain - - - 4.697e-301 966.0
TLS3_k127_1995834_1 membrane K13277,K15125,K15539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 627.0
TLS3_k127_1995834_2 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000008641 127.0
TLS3_k127_2000886_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 420.0
TLS3_k127_2000886_1 Extradiol ring-cleavage dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 341.0
TLS3_k127_2000886_2 - - - - 0.0000000000000000000000000000000000000000000000000000000003768 210.0
TLS3_k127_2000886_3 Transcriptional regulator - - - 0.000000000000000000000004404 105.0
TLS3_k127_2004192_0 Pas domain K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 391.0
TLS3_k127_2004192_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 321.0
TLS3_k127_2004192_2 PFAM alpha beta hydrolase fold K01055,K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000001193 144.0
TLS3_k127_2023338_0 Glycosyl transferase family 2 K12984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 355.0
TLS3_k127_2023338_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 306.0
TLS3_k127_2023338_2 PFAM Glycosyl transferase family 4 K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001414 271.0
TLS3_k127_2023338_3 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000001137 222.0
TLS3_k127_2023338_4 Glycosyl transferase family 2 K12984 - - 0.000000000000000000000000000000000000000000000000002145 198.0
TLS3_k127_2023338_5 heptosyltransferase K02849 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:0071967,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000001491 124.0
TLS3_k127_2036037_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 7.669e-220 688.0
TLS3_k127_2036037_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 507.0
TLS3_k127_2036037_2 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 372.0
TLS3_k127_2036037_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 307.0
TLS3_k127_2037617_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 4.157e-241 751.0
TLS3_k127_2037617_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000000000000000000000000000000000000000001203 198.0
TLS3_k127_2037617_2 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000001174 164.0
TLS3_k127_2037617_3 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000000000000000000000003104 159.0
TLS3_k127_2076216_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.139e-223 709.0
TLS3_k127_2076216_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.946e-214 668.0
TLS3_k127_2076216_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 601.0
TLS3_k127_2076216_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 418.0
TLS3_k127_2076216_4 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 329.0
TLS3_k127_2076216_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000023 228.0
TLS3_k127_2076216_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000282 200.0
TLS3_k127_2076216_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000005112 106.0
TLS3_k127_2076216_8 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000001182 91.0
TLS3_k127_2082239_0 antibiotic catabolic process K13277 - - 0.0000000000000000000000000000000000000000000000000000009172 198.0
TLS3_k127_2082239_1 - - - - 0.00000000000000000000000000000000000000000000000000007005 199.0
TLS3_k127_2082239_2 Transposase DDE domain - - - 0.00000000000000000000000000005574 124.0
TLS3_k127_2082239_3 Transposase DDE domain - - - 0.0000000000000000000001675 99.0
TLS3_k127_2082239_4 Transposase DDE domain - - - 0.000000000000000000001192 95.0
TLS3_k127_2082239_5 COG3666 Transposase and inactivated derivatives - - - 0.00000000000000005577 83.0
TLS3_k127_2082239_6 Ferritin-like domain - - - 0.00000000004932 69.0
TLS3_k127_2082239_7 Transposase DDE domain - - - 0.0000000006125 60.0
TLS3_k127_2094301_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01153 - 3.1.21.3 4.784e-307 946.0
TLS3_k127_2094301_1 Putative DNA-binding domain - - - 0.00002662 48.0
TLS3_k127_209529_0 antisigma factor binding K17763 - - 0.0000000000000000000004754 101.0
TLS3_k127_210583_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 361.0
TLS3_k127_210583_2 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000001399 181.0
TLS3_k127_210583_3 IMP dehydrogenase activity K09137 - - 0.00000000000000000000000000000000000000006323 155.0
TLS3_k127_2106461_0 Histidine kinase-like ATPase domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 338.0
TLS3_k127_2106461_1 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0006253 47.0
TLS3_k127_2109677_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 371.0
TLS3_k127_2109677_1 - - - - 0.00000000000000000000000000000001154 138.0
TLS3_k127_2116857_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 543.0
TLS3_k127_2116857_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000002197 176.0
TLS3_k127_2118835_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.796e-227 711.0
TLS3_k127_2118835_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000004162 241.0
TLS3_k127_2118835_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000003854 204.0
TLS3_k127_2118835_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000007198 192.0
TLS3_k127_2131077_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 550.0
TLS3_k127_2131077_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002501 232.0
TLS3_k127_2131077_2 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000009814 199.0
TLS3_k127_2131077_3 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000000000000005312 127.0
TLS3_k127_2131077_4 - - - - 0.00000000000000003218 84.0
TLS3_k127_2131077_6 DNA-binding transcription factor activity - - - 0.0003029 50.0
TLS3_k127_2134885_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000002621 235.0
TLS3_k127_2134885_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000004802 219.0
TLS3_k127_2134885_2 Domain of unknown function (DUF4440) - - - 0.00000174 51.0
TLS3_k127_2165878_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 2.111e-289 909.0
TLS3_k127_2165878_1 Tetratricopeptide repeat - - - 8.065e-235 732.0
TLS3_k127_2165878_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001315 282.0
TLS3_k127_2165878_11 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000004046 262.0
TLS3_k127_2165878_12 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000002277 195.0
TLS3_k127_2165878_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000002261 185.0
TLS3_k127_2165878_14 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000003435 163.0
TLS3_k127_2165878_15 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001739 159.0
TLS3_k127_2165878_16 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000009122 158.0
TLS3_k127_2165878_17 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000003236 152.0
TLS3_k127_2165878_18 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000000005085 145.0
TLS3_k127_2165878_2 Phosphoglycerate kinase K00927 - 2.7.2.3 6.331e-220 686.0
TLS3_k127_2165878_20 - - - - 0.00002906 52.0
TLS3_k127_2165878_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 581.0
TLS3_k127_2165878_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 568.0
TLS3_k127_2165878_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 530.0
TLS3_k127_2165878_6 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 520.0
TLS3_k127_2165878_7 Multicopper oxidase K00368,K22349 - 1.16.3.3,1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 457.0
TLS3_k127_2165878_8 phosphorelay signal transduction system K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 457.0
TLS3_k127_2165878_9 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 393.0
TLS3_k127_21687_0 PFAM CreA family protein K05805 - - 0.000000000000000000000000000000000000000000000000000000000003158 211.0
TLS3_k127_21687_1 YaeQ - - - 0.00000000000000000000000000000000000000000000003781 172.0
TLS3_k127_21687_2 endonuclease activity K03465 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.1.1.148 0.000000000000000000000000000000000000000000000583 168.0
TLS3_k127_21687_3 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000003049 119.0
TLS3_k127_21687_4 conserved protein (DUF2132) K06867 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000001042 104.0
TLS3_k127_2207181_0 type III restriction protein res subunit K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000003677 248.0
TLS3_k127_2207181_1 - - - - 0.00000000000000000000000002767 108.0
TLS3_k127_2207181_2 Histidine kinase - - - 0.00006125 48.0
TLS3_k127_2207370_0 radical SAM domain protein - - - 1.594e-292 902.0
TLS3_k127_2207370_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 504.0
TLS3_k127_2207370_2 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 446.0
TLS3_k127_2207370_3 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000203 271.0
TLS3_k127_2207370_4 PFAM AIG2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004219 239.0
TLS3_k127_2207370_5 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000002145 203.0
TLS3_k127_2207370_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000002713 197.0
TLS3_k127_2211772_0 Membrane K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 295.0
TLS3_k127_2211772_1 Membrane K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001949 261.0
TLS3_k127_2211772_2 AhpC/TSA family K03386 - 1.11.1.15 0.000000006054 61.0
TLS3_k127_2226132_0 pyruvate decarboxylase activity K04103 - 4.1.1.74 4.15e-274 851.0
TLS3_k127_2226132_1 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 4.203e-214 672.0
TLS3_k127_2226132_2 protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 562.0
TLS3_k127_2226132_3 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 384.0
TLS3_k127_2226132_4 mannosylglycerate metabolic process K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 287.0
TLS3_k127_2226132_5 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002 258.0
TLS3_k127_2226132_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003112 243.0
TLS3_k127_2226132_7 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000003101 238.0
TLS3_k127_2226132_8 Peptidoglycan-synthase activator LpoB K07337 - - 0.000000000000003585 75.0
TLS3_k127_2235558_0 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 370.0
TLS3_k127_2235558_1 - - - - 0.00000000000000000000000000000000000007914 147.0
TLS3_k127_2235558_2 - - - - 0.000000000000000005525 94.0
TLS3_k127_2235558_3 - - - - 0.0000004143 61.0
TLS3_k127_2261250_0 AI-2E family transporter - - - 1.078e-214 685.0
TLS3_k127_2261250_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 384.0
TLS3_k127_2261250_2 Thioredoxin reductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001664 287.0
TLS3_k127_2265239_0 xylulokinase activity K00854 - 2.7.1.17 0.0 1017.0
TLS3_k127_2265239_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 564.0
TLS3_k127_2265239_2 - - - - 0.0000000000000000000000000000000000000001896 153.0
TLS3_k127_2265239_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.000000000000000000000000000000000003461 139.0
TLS3_k127_2265239_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000000003204 135.0
TLS3_k127_2265239_5 Protein conserved in bacteria - - - 0.0000000000000000000000000001202 117.0
TLS3_k127_2265239_6 AAA domain - - - 0.00000000000000001655 86.0
TLS3_k127_2265239_7 - - - - 0.0000000000001835 74.0
TLS3_k127_2265239_8 - - - - 0.0001485 45.0
TLS3_k127_2266556_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 8.884e-274 847.0
TLS3_k127_2266556_1 Carbon-nitrogen hydrolase K03820 - - 1.51e-205 653.0
TLS3_k127_2266556_10 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 302.0
TLS3_k127_2266556_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003124 240.0
TLS3_k127_2266556_12 CAAX protease self-immunity K07052 - - 0.000000000000000000000000001283 121.0
TLS3_k127_2266556_14 - - - - 0.00000000000000000000005491 105.0
TLS3_k127_2266556_15 - - - - 0.0000000000000000000005891 98.0
TLS3_k127_2266556_16 cellulose binding K01179 - 3.2.1.4 0.000000000000000007286 99.0
TLS3_k127_2266556_17 Galactose oxidase, central domain - - - 0.00000000000004093 72.0
TLS3_k127_2266556_18 NACHT domain - - - 0.00000000000006005 86.0
TLS3_k127_2266556_19 coenzyme F420 binding K07226 - - 0.00000000001729 66.0
TLS3_k127_2266556_2 MacB-like periplasmic core domain K09808 - - 1.598e-197 623.0
TLS3_k127_2266556_20 - - - - 0.0000000004318 65.0
TLS3_k127_2266556_21 - - - - 0.0000000005547 64.0
TLS3_k127_2266556_22 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00002225 51.0
TLS3_k127_2266556_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 576.0
TLS3_k127_2266556_4 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 434.0
TLS3_k127_2266556_5 Galactose oxidase, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 374.0
TLS3_k127_2266556_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 363.0
TLS3_k127_2266556_7 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 374.0
TLS3_k127_2266556_8 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 336.0
TLS3_k127_2266556_9 Elements of external origin K07494 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 317.0
TLS3_k127_2308848_0 Pup-ligase protein K20814 - 3.5.1.119 1.297e-265 824.0
TLS3_k127_2308848_1 Pup-ligase protein K13571 - 6.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 476.0
TLS3_k127_2308848_2 Proteasome subunit K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 432.0
TLS3_k127_2308848_3 Proteasome subunit K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 308.0
TLS3_k127_2308848_4 Proteasomal ATPase OB/ID domain K13527 - - 0.00000000000000000000000000000000000000000000000000003201 188.0
TLS3_k127_2308848_5 May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes - - - 0.0000000000000000000001606 97.0
TLS3_k127_234668_0 mechanosensitive ion channel activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 586.0
TLS3_k127_234668_2 Ammonium transporter K03320,K06580 - - 0.00000000000000000000000000000000000000000000003461 173.0
TLS3_k127_2378140_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001885 252.0
TLS3_k127_2378140_1 - - - - 0.00000000000000000000000000006244 125.0
TLS3_k127_2378140_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.0000000000000000000000008317 104.0
TLS3_k127_2378140_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.0000000000000000000002921 96.0
TLS3_k127_2378140_4 - - - - 0.00000000000000001659 93.0
TLS3_k127_2378140_5 Evidence 2b Function of strongly homologous gene K07497 - - 0.00000000000000006554 81.0
TLS3_k127_2389566_0 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 485.0
TLS3_k127_2389566_1 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 452.0
TLS3_k127_2389566_2 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000002933 200.0
TLS3_k127_2389566_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000001599 156.0
TLS3_k127_2389566_4 TonB-dependent receptor K02014 - - 0.000000000000000000000000000009948 120.0
TLS3_k127_2394912_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 359.0
TLS3_k127_2394912_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 305.0
TLS3_k127_2394912_2 Pilus assembly protein PilX K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003788 259.0
TLS3_k127_2394912_3 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000001108 198.0
TLS3_k127_2394912_4 Putative Competence protein ComGF K02246,K02248 - - 0.00000000000000000000000000000002437 135.0
TLS3_k127_2394912_5 pilus assembly protein PilW K02672 - - 0.0000000000000000000000000000004042 133.0
TLS3_k127_2394912_6 response regulator K03413 - - 0.0000000000000000000000000002064 117.0
TLS3_k127_2394912_7 protein transport across the cell outer membrane K02457,K02672,K08084,K08085 - - 0.0000000000000000000776 96.0
TLS3_k127_2403848_0 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 552.0
TLS3_k127_2403848_2 Animal haem peroxidase - - - 0.00000004624 58.0
TLS3_k127_2425800_0 Domain of unknown function (DUF4105) - - - 4.058e-306 954.0
TLS3_k127_2425800_1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 1.716e-199 627.0
TLS3_k127_2425800_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000003534 139.0
TLS3_k127_2425800_11 Domain of unknown function (DUF3332) - - - 0.00000000002815 72.0
TLS3_k127_2425800_12 TRL-like protein family - - - 0.0005076 46.0
TLS3_k127_2425800_2 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 400.0
TLS3_k127_2425800_3 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 372.0
TLS3_k127_2425800_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 323.0
TLS3_k127_2425800_5 Protein of unknown function (DUF3015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002404 262.0
TLS3_k127_2425800_6 transferase activity, transferring glycosyl groups K20742 - 3.4.14.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000222 262.0
TLS3_k127_2425800_7 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000001302 191.0
TLS3_k127_2426819_0 PFAM transposase IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 351.0
TLS3_k127_2426819_1 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000003135 181.0
TLS3_k127_2426819_2 PFAM Transposase IS116 IS110 IS902 family, Transposase - - - 0.00005135 49.0
TLS3_k127_2427250_0 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 432.0
TLS3_k127_2427250_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 369.0
TLS3_k127_2427250_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000001555 249.0
TLS3_k127_2433221_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000002519 97.0
TLS3_k127_2438319_0 Cytidylyltransferase K00983 - 2.7.7.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 323.0
TLS3_k127_2438319_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.00000000000000000000000000000001884 129.0
TLS3_k127_2438319_3 synthase K01654 - 2.5.1.56 0.000000000000002081 78.0
TLS3_k127_2439392_0 Peptidase C39 family K06147 - - 7.327e-279 874.0
TLS3_k127_2439392_1 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000006477 167.0
TLS3_k127_2439392_2 - - - - 0.0000000000000000000000000006977 122.0
TLS3_k127_2439392_3 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.00000000000005859 76.0
TLS3_k127_2439392_4 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.0000000000001773 73.0
TLS3_k127_2439392_5 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.000000000001378 72.0
TLS3_k127_2439392_6 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.000000000002232 69.0
TLS3_k127_2439392_7 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.000000000002633 70.0
TLS3_k127_2439392_8 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.000000000004861 68.0
TLS3_k127_2439392_9 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.0000000001394 66.0
TLS3_k127_2443059_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 496.0
TLS3_k127_2443059_1 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 364.0
TLS3_k127_2443059_2 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000004679 226.0
TLS3_k127_2443059_3 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000001627 179.0
TLS3_k127_2443059_4 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000001208 172.0
TLS3_k127_2443059_5 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000378 156.0
TLS3_k127_2443059_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000003136 106.0
TLS3_k127_2478009_0 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 406.0
TLS3_k127_2478009_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000001903 237.0
TLS3_k127_2478009_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000003771 124.0
TLS3_k127_2491496_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1399.0
TLS3_k127_2491496_1 Eco57I restriction-modification methylase - - - 4.258e-272 852.0
TLS3_k127_2491496_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001072 249.0
TLS3_k127_2491496_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000112 210.0
TLS3_k127_2491496_12 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000000000000000000000000000000001278 198.0
TLS3_k127_2491496_15 GGDEF domain containing protein - - - 0.00000000000000000000008978 112.0
TLS3_k127_2491496_16 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000005569 104.0
TLS3_k127_2491496_17 CsbD-like - - - 0.00000000000001318 77.0
TLS3_k127_2491496_18 phosphorelay signal transduction system - - - 0.00000000000003564 78.0
TLS3_k127_2491496_19 Protein of unknown function (DUF1328) - - - 0.00001857 51.0
TLS3_k127_2491496_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 4.806e-228 713.0
TLS3_k127_2491496_20 - - - - 0.0000421 53.0
TLS3_k127_2491496_3 phosphorelay signal transduction system - - - 3.951e-205 649.0
TLS3_k127_2491496_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 567.0
TLS3_k127_2491496_5 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 520.0
TLS3_k127_2491496_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 480.0
TLS3_k127_2491496_7 Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 487.0
TLS3_k127_2491496_8 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 309.0
TLS3_k127_2491496_9 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 312.0
TLS3_k127_2494929_0 TonB-dependent receptor K16091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 603.0
TLS3_k127_2494929_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000001226 163.0
TLS3_k127_2494929_2 - - - - 0.000004706 51.0
TLS3_k127_2519713_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 415.0
TLS3_k127_2519713_1 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000000000000000000000000000000000001065 207.0
TLS3_k127_2519713_2 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563,K13626 - - 0.000000000000000000000000009338 111.0
TLS3_k127_2519713_3 Flagellar hook-associated protein 3 K02397 - - 0.0006313 48.0
TLS3_k127_2522119_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.66e-248 769.0
TLS3_k127_2522119_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002066 259.0
TLS3_k127_2522119_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003071 223.0
TLS3_k127_2522119_3 integral membrane protein - - - 0.0000000000000000000000000000000005955 136.0
TLS3_k127_2522119_4 Glycosyl transferase family 41 - - - 0.00004552 50.0
TLS3_k127_2524196_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 359.0
TLS3_k127_2524196_1 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000006542 214.0
TLS3_k127_2532851_0 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 432.0
TLS3_k127_2532851_1 PFAM binding-protein-dependent transport systems inner membrane component K02046,K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 419.0
TLS3_k127_2532851_2 sulfate ABC transporter K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 384.0
TLS3_k127_2532851_3 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000001936 232.0
TLS3_k127_2550678_0 PFAM Alcohol dehydrogenase - - - 8.885e-202 633.0
TLS3_k127_2550678_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007685 263.0
TLS3_k127_2578924_0 Sodium/hydrogen exchanger family K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 541.0
TLS3_k127_2578924_1 Sigma-54 interaction domain K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 520.0
TLS3_k127_2578924_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 492.0
TLS3_k127_2578924_3 TrkA-N domain K03455,K10716 - - 0.0000000000000000000000000000000000000000000000000000000004278 206.0
TLS3_k127_2578924_4 TrkA-N domain K03455,K10716 - - 0.00000000000000000000000000000000000000005467 153.0
TLS3_k127_2578924_5 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000000277 135.0
TLS3_k127_2578924_8 Hydrophobe amphiphile efflux-1 HAE1 K03296,K18138 - - 0.0004566 43.0
TLS3_k127_258660_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1043.0
TLS3_k127_258660_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.627e-313 974.0
TLS3_k127_258660_10 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 298.0
TLS3_k127_258660_11 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 299.0
TLS3_k127_258660_12 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 289.0
TLS3_k127_258660_13 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004276 272.0
TLS3_k127_258660_14 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000178 163.0
TLS3_k127_258660_16 Protein conserved in bacteria - - - 0.00000886 48.0
TLS3_k127_258660_17 Protein conserved in bacteria - - - 0.000946 44.0
TLS3_k127_258660_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700,K01236 - 2.4.1.18,3.2.1.141 2.381e-210 675.0
TLS3_k127_258660_3 Glycosyl transferase, family 2 K21349 - 2.4.1.268 1.466e-208 656.0
TLS3_k127_258660_4 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 5.044e-204 641.0
TLS3_k127_258660_5 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 494.0
TLS3_k127_258660_6 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 385.0
TLS3_k127_258660_7 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 387.0
TLS3_k127_258660_8 mannosylglycerate metabolic process K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 307.0
TLS3_k127_258660_9 Binding-protein-dependent transport system inner membrane component K02025,K10237,K15771 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 308.0
TLS3_k127_2597202_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 319.0
TLS3_k127_2597202_1 response regulator K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008203 247.0
TLS3_k127_2597202_2 Response regulator receiver - - - 0.0000000000000000000000403 104.0
TLS3_k127_2597202_3 peptidase - - - 0.00000000000000000003109 94.0
TLS3_k127_259934_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 8.964e-248 768.0
TLS3_k127_259934_1 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 458.0
TLS3_k127_259934_2 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 323.0
TLS3_k127_259934_3 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 319.0
TLS3_k127_259934_4 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000000000000000000000000000000000021 203.0
TLS3_k127_259934_6 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000007431 188.0
TLS3_k127_259934_7 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.0000000000000000000000000000000000000000000000003482 179.0
TLS3_k127_2608252_0 Type ii secretion system protein e K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 570.0
TLS3_k127_2608252_1 ABC-type multidrug transport system ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 550.0
TLS3_k127_2608252_10 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000009871 199.0
TLS3_k127_2608252_11 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000003526 148.0
TLS3_k127_2608252_12 AAA domain K02282 - - 0.0000000000000000000000000000000004783 146.0
TLS3_k127_2608252_13 - - - - 0.000000000000000000000000000000007184 135.0
TLS3_k127_2608252_14 - - - - 0.00000000000000000000000001041 117.0
TLS3_k127_2608252_15 PFAM Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.00000000000000000000004194 107.0
TLS3_k127_2608252_16 PFAM TadE family protein - - - 0.000000000000000000003681 98.0
TLS3_k127_2608252_17 Putative Tad-like Flp pilus-assembly - - - 0.000000000000000001252 98.0
TLS3_k127_2608252_18 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.0000000007791 61.0
TLS3_k127_2608252_2 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 484.0
TLS3_k127_2608252_21 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K10936,K16079 - - 0.00005682 53.0
TLS3_k127_2608252_22 PFAM Flp Fap pilin component K02651 - - 0.00006493 48.0
TLS3_k127_2608252_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 428.0
TLS3_k127_2608252_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 349.0
TLS3_k127_2608252_5 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007273 276.0
TLS3_k127_2608252_6 type II secretion system protein K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008137 248.0
TLS3_k127_2608252_7 Type II secretion system (T2SS), protein F - - - 0.000000000000000000000000000000000000000000000000000000000002873 220.0
TLS3_k127_2608252_8 Flp pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000001767 201.0
TLS3_k127_2608252_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001741 204.0
TLS3_k127_2625150_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 449.0
TLS3_k127_2625150_2 RNA recognition motif - - - 0.000000000000000000000000000000000000000001205 160.0
TLS3_k127_2625150_4 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000004708 69.0
TLS3_k127_2671857_0 protein secretion by the type I secretion system K11004 - - 0.0 1077.0
TLS3_k127_2671857_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 2.176e-254 805.0
TLS3_k127_2671857_11 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000001824 188.0
TLS3_k127_2671857_12 PFAM Fimbrial assembly family protein K02461,K02662,K02663,K12289 - - 0.00000000000000000000000000000000000000000004951 167.0
TLS3_k127_2671857_13 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000001593 158.0
TLS3_k127_2671857_14 sequence-specific DNA binding - - - 0.0000000000000000000000000000004949 127.0
TLS3_k127_2671857_16 phosphorelay signal transduction system K02535 - 3.5.1.108 0.0000000000000000000000007905 109.0
TLS3_k127_2671857_2 Sigma-54 interaction domain K07714 - - 2.838e-209 666.0
TLS3_k127_2671857_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 3.891e-198 626.0
TLS3_k127_2671857_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K11003,K12532 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 602.0
TLS3_k127_2671857_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 567.0
TLS3_k127_2671857_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 439.0
TLS3_k127_2671857_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 435.0
TLS3_k127_2671857_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001364 280.0
TLS3_k127_2671857_9 general secretion pathway protein K10927 - - 0.000000000000000000000000000000000000000000000000000000000006235 214.0
TLS3_k127_2672586_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0 1052.0
TLS3_k127_2672586_1 Sugar (and other) transporter K08178 - - 7.792e-212 664.0
TLS3_k127_2672586_10 metallopeptidase activity K07404 - 3.1.1.31 0.000000000000000000002106 107.0
TLS3_k127_2672586_12 radical SAM domain protein K06871 - - 0.00000000000000008031 88.0
TLS3_k127_2672586_14 Protein of unknown function (DUF3047) - - - 0.000000004258 59.0
TLS3_k127_2672586_15 Glycosyl transferase family 2 - - - 0.0000249 54.0
TLS3_k127_2672586_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 595.0
TLS3_k127_2672586_3 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 518.0
TLS3_k127_2672586_4 Evidence 2b Function of strongly homologous gene K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 507.0
TLS3_k127_2672586_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 409.0
TLS3_k127_2672586_6 heat shock protein binding K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001978 277.0
TLS3_k127_2672586_7 ADP-glyceromanno-heptose 6-epimerase activity K00311 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001086 266.0
TLS3_k127_2672586_8 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000116 129.0
TLS3_k127_2672586_9 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000005634 125.0
TLS3_k127_2694175_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 1.32e-286 904.0
TLS3_k127_2694175_1 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 505.0
TLS3_k127_2694175_2 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 462.0
TLS3_k127_2694175_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 377.0
TLS3_k127_2694175_4 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 363.0
TLS3_k127_2694175_5 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001013 284.0
TLS3_k127_2755828_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1318.0
TLS3_k127_2755828_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.801e-217 691.0
TLS3_k127_2763460_0 AcrB/AcrD/AcrF family - - - 0.0 1675.0
TLS3_k127_2763460_1 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 549.0
TLS3_k127_2763460_2 nitric oxide dioxygenase activity K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 305.0
TLS3_k127_2763460_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001314 259.0
TLS3_k127_2763460_4 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.000000000000000000000000000000000000000000000000000000000199 205.0
TLS3_k127_2763460_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000001215 182.0
TLS3_k127_2763460_6 Sterol carrier protein - - - 0.000000000000000000000000000000000000037 147.0
TLS3_k127_2766969_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 565.0
TLS3_k127_2766969_1 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 426.0
TLS3_k127_2766969_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 371.0
TLS3_k127_2766969_3 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000000000002509 209.0
TLS3_k127_277479_0 FAD binding domain K05797 - 1.17.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 386.0
TLS3_k127_277479_1 cytochrome C peroxidase - - - 0.0000000008166 61.0
TLS3_k127_2776748_0 'glutamate synthase K00528,K03388 - 1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.861e-230 719.0
TLS3_k127_2776748_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 450.0
TLS3_k127_2776748_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 408.0
TLS3_k127_2776748_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 308.0
TLS3_k127_2776748_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 281.0
TLS3_k127_2776748_6 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000001573 242.0
TLS3_k127_2794608_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 465.0
TLS3_k127_2794608_1 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000007202 135.0
TLS3_k127_2794608_2 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.000000000000001559 80.0
TLS3_k127_2800373_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.454e-267 824.0
TLS3_k127_2800373_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 511.0
TLS3_k127_2800373_10 Tetratricopeptide TPR_2 repeat protein - - - 0.00000007363 64.0
TLS3_k127_2800373_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 398.0
TLS3_k127_2800373_3 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 360.0
TLS3_k127_2800373_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000008041 243.0
TLS3_k127_2800373_5 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000000000000000000009451 183.0
TLS3_k127_2800373_6 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000000001844 138.0
TLS3_k127_2800373_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000485 111.0
TLS3_k127_2800373_8 YCII-related domain K05527,K09780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000003386 84.0
TLS3_k127_2800373_9 - - - - 0.00000000108 70.0
TLS3_k127_2805728_0 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 8.781e-222 705.0
TLS3_k127_2805728_1 Glycogen debranching enzyme - - - 6.994e-215 687.0
TLS3_k127_2805728_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000009519 115.0
TLS3_k127_2805728_3 PFAM ROK family K00886 - 2.7.1.63 0.00001261 49.0
TLS3_k127_2843974_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1605.0
TLS3_k127_2843974_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 345.0
TLS3_k127_2843974_10 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000002956 194.0
TLS3_k127_2843974_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000006237 190.0
TLS3_k127_2843974_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000001632 122.0
TLS3_k127_2843974_2 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 345.0
TLS3_k127_2843974_3 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 339.0
TLS3_k127_2843974_4 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 330.0
TLS3_k127_2843974_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 316.0
TLS3_k127_2843974_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000002841 230.0
TLS3_k127_2843974_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000000000003711 227.0
TLS3_k127_2843974_8 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000003064 218.0
TLS3_k127_2843974_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06991 - - 0.000000000000000000000000000000000000000000000000000000006356 204.0
TLS3_k127_2851139_0 phosphorelay signal transduction system K10941 - - 9.438e-212 667.0
TLS3_k127_2851139_1 peptidyl-tyrosine sulfation - - - 0.00000000005184 71.0
TLS3_k127_2851139_2 DNA integration - - - 0.000002057 49.0
TLS3_k127_2869303_0 sodium:proton antiporter activity K03316 - - 7.981e-228 715.0
TLS3_k127_2869303_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 536.0
TLS3_k127_2869303_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 509.0
TLS3_k127_2869303_3 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 486.0
TLS3_k127_2869303_4 tRNA processing K04075,K14058,K21947 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.1.15,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 428.0
TLS3_k127_2869303_5 - - - - 0.000000000000000000000000000000000000000000000000000000001882 207.0
TLS3_k127_2869303_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.00000000000000000000000000000000000000000003007 167.0
TLS3_k127_2869303_7 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.0000000000000000000003349 96.0
TLS3_k127_288568_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 363.0
TLS3_k127_288568_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000409 193.0
TLS3_k127_2889609_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1553.0
TLS3_k127_2889609_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 7.684e-207 647.0
TLS3_k127_2889609_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 381.0
TLS3_k127_2889609_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000001721 238.0
TLS3_k127_2889609_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000005417 138.0
TLS3_k127_2889609_6 photosystem II stabilization K02237 - - 0.00007088 48.0
TLS3_k127_2900529_0 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 412.0
TLS3_k127_2900529_1 Protein of unknown function (DUF3422) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 420.0
TLS3_k127_2900529_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 391.0
TLS3_k127_2900529_3 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 297.0
TLS3_k127_2900529_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000005993 64.0
TLS3_k127_2905916_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.83e-322 994.0
TLS3_k127_2905916_1 Aldehyde dehydrogenase family - - - 2.849e-207 655.0
TLS3_k127_2905916_2 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 590.0
TLS3_k127_2905916_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 539.0
TLS3_k127_2905916_4 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 343.0
TLS3_k127_2905916_5 arginine decarboxylase activity K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 336.0
TLS3_k127_2905916_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 299.0
TLS3_k127_2905916_8 Transcriptional regulator K03717 - - 0.0000000001614 62.0
TLS3_k127_2933409_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 5.757e-303 937.0
TLS3_k127_2933409_1 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 475.0
TLS3_k127_2933409_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000002793 224.0
TLS3_k127_2933409_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000103 183.0
TLS3_k127_2933409_4 Acyl-homoserine-lactone synthase K13060,K13061,K18096,K20248,K20249,K20250 - 2.3.1.184,2.3.1.228,2.3.1.229 0.00000000000000000000000000000000000000000001058 171.0
TLS3_k127_2933409_5 Autoinducer binding domain - - - 0.000000000000000000000000000000007593 138.0
TLS3_k127_2933409_6 Histidine kinase K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.0000000000000000000000000002382 124.0
TLS3_k127_2933409_7 response regulator - - - 0.000000000000000002124 87.0
TLS3_k127_2935292_0 Inosine-uridine preferring nucleoside hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004223 279.0
TLS3_k127_2935292_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004381 251.0
TLS3_k127_2935292_10 Stage II sporulation protein E (SpoIIE) - - - 0.000002778 56.0
TLS3_k127_2935292_11 Two component transcriptional regulator, LuxR family - - - 0.0008146 43.0
TLS3_k127_2935292_2 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005239 239.0
TLS3_k127_2935292_3 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000297 205.0
TLS3_k127_2935292_4 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000002309 104.0
TLS3_k127_2935292_5 Pfam Hemerythrin HHE cation binding domain - - - 0.0000000000000000000004285 102.0
TLS3_k127_2935292_6 Domain of unknown function (DUF3943) - - - 0.0000000000000000003536 100.0
TLS3_k127_2935292_7 hydrolase activity, acting on ester bonds - - - 0.0000000000009492 79.0
TLS3_k127_294177_0 methyltransferase K09846 - 2.1.1.210 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 502.0
TLS3_k127_294177_1 - - - - 0.0000000000000000000000000000001404 128.0
TLS3_k127_2949720_0 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 504.0
TLS3_k127_2949720_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 398.0
TLS3_k127_2949720_2 phosphoprotein phosphatase activity K01525 GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 346.0
TLS3_k127_2949720_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000006054 237.0
TLS3_k127_2949720_4 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000000000000000000000000000007073 168.0
TLS3_k127_2949720_5 Putative addiction module component - - - 0.00000000000000000003989 93.0
TLS3_k127_2949720_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000001858 61.0
TLS3_k127_2950637_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 374.0
TLS3_k127_2950637_2 - - - - 0.000000000000000000000000000000000008753 145.0
TLS3_k127_2950637_3 Transposase K02557,K07484,K13924,K21471 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000002414 152.0
TLS3_k127_2950637_4 - - - - 0.000000000000000000000004061 102.0
TLS3_k127_2950637_5 LysR substrate binding domain K03717 - - 0.0000001318 55.0
TLS3_k127_2965954_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 602.0
TLS3_k127_2965954_1 DNA integration - - - 0.000000000000000000000008768 104.0
TLS3_k127_2965954_2 Integrase core domain - - - 0.0000000001985 68.0
TLS3_k127_2975130_0 FtsX-like permease family K02004 - - 5.171e-307 962.0
TLS3_k127_2975130_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 341.0
TLS3_k127_2975130_2 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 318.0
TLS3_k127_2975130_4 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000007612 261.0
TLS3_k127_2975130_5 zinc ion binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000001145 200.0
TLS3_k127_2989302_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1073.0
TLS3_k127_2989302_1 ribosome binding - - - 2.265e-242 782.0
TLS3_k127_2989302_2 ATPase involved in DNA repair - - - 1.448e-215 711.0
TLS3_k127_2989302_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 484.0
TLS3_k127_2989302_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071236,GO:0140096 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 276.0
TLS3_k127_2989302_5 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K01115 - 3.1.4.4 0.0000000000000000000000000000000000000000000001656 191.0
TLS3_k127_2989302_6 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000001482 147.0
TLS3_k127_2998299_0 DUF based on E. rectale Gene description (DUF3880) K06320 - - 1.526e-218 693.0
TLS3_k127_2998299_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 541.0
TLS3_k127_2998299_2 belongs to the thioredoxin family K02453,K07280,K20444,K20543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 530.0
TLS3_k127_2998299_3 rRNA (adenine-N6,N6-)-dimethyltransferase activity K02528,K20444 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 342.0
TLS3_k127_2998299_4 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000403 290.0
TLS3_k127_3002857_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.325e-258 804.0
TLS3_k127_3002857_1 cellulose synthase K00694 - 2.4.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 386.0
TLS3_k127_3002857_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 346.0
TLS3_k127_3002857_3 Magnesium transport protein CorA K03284 GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002973 256.0
TLS3_k127_3002857_4 MEKHLA domain - - - 0.000000000000000000000000000000000000000000000000000000004485 203.0
TLS3_k127_3002857_5 CBS-domain-containing membrane protein K07168 - - 0.00000000003399 72.0
TLS3_k127_3007257_0 protein secretion by the type I secretion system K02021 - - 5.549e-211 669.0
TLS3_k127_3007257_1 efflux transmembrane transporter activity - - - 1.045e-197 625.0
TLS3_k127_3007257_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 341.0
TLS3_k127_3021881_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 606.0
TLS3_k127_3021881_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002594 258.0
TLS3_k127_3021881_2 Cytochrome c K02305,K17223 - - 0.00000000000000000000000000000000005734 138.0
TLS3_k127_3021881_3 - - - - 0.0000000000000000000000000000000004626 133.0
TLS3_k127_3024982_0 ATPase activity - - - 1.163e-263 819.0
TLS3_k127_3024982_1 Periplasmic binding protein - - - 1.236e-227 722.0
TLS3_k127_3024982_10 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000000000000000000000000000000004545 224.0
TLS3_k127_3024982_12 - - - - 0.00000000000000000000000000000000000000000000000000003853 190.0
TLS3_k127_3024982_13 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000001395 194.0
TLS3_k127_3024982_15 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000138 94.0
TLS3_k127_3024982_16 - - - - 0.000000000002232 69.0
TLS3_k127_3024982_17 PEGA domain - - - 0.0000008195 57.0
TLS3_k127_3024982_18 energy transducer activity K03646,K03832 - - 0.000003133 55.0
TLS3_k127_3024982_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 552.0
TLS3_k127_3024982_20 - - - - 0.0009645 43.0
TLS3_k127_3024982_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 459.0
TLS3_k127_3024982_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 346.0
TLS3_k127_3024982_5 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001875 288.0
TLS3_k127_3024982_7 cysteine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001823 250.0
TLS3_k127_3024982_8 Domain of unknown function (DUF5069) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000384 239.0
TLS3_k127_3024982_9 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000004746 235.0
TLS3_k127_3035385_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 1418.0
TLS3_k127_3035385_1 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 601.0
TLS3_k127_3035385_2 - - - - 0.0000000000002927 70.0
TLS3_k127_303862_0 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001278 276.0
TLS3_k127_303862_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000000002967 231.0
TLS3_k127_303862_2 transposition K07497 - - 0.0000000000000000000000000000000000000000003121 162.0
TLS3_k127_303862_3 transposase activity K07483,K07497 - - 0.0000000000000000000000000000000000000008252 149.0
TLS3_k127_303862_4 transposition K07497 - - 0.00000000007374 64.0
TLS3_k127_303862_5 Transposase and inactivated derivatives - - - 0.00008039 50.0
TLS3_k127_3055528_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 563.0
TLS3_k127_3055528_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 524.0
TLS3_k127_3055528_2 protein secretion by the type I secretion system K02021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 463.0
TLS3_k127_3055528_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 435.0
TLS3_k127_3055528_4 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 424.0
TLS3_k127_3055528_5 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 344.0
TLS3_k127_3055528_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001321 230.0
TLS3_k127_3055528_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000002657 79.0
TLS3_k127_3061118_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 6.742e-275 869.0
TLS3_k127_3061118_1 Bacterioferritin (cytochrome b1) K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000005897 215.0
TLS3_k127_3061118_10 Helix-hairpin-helix motif - - - 0.0003006 46.0
TLS3_k127_3061118_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000000004458 172.0
TLS3_k127_3061118_3 Bacterial protein of unknown function (DUF948) - - - 0.000000000000000000000000000000551 126.0
TLS3_k127_3061118_4 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000001468 102.0
TLS3_k127_3061118_5 Bacterioferritin (cytochrome b1) K03594 - 1.16.3.1 0.000000000000003525 77.0
TLS3_k127_3061118_6 - - - - 0.000000000000004264 82.0
TLS3_k127_3061118_7 Transposase DDE domain - - - 0.000000000004849 70.0
TLS3_k127_3061118_8 Protein of unknown function (DUF3309) - - - 0.00000000001892 65.0
TLS3_k127_3061118_9 YtxH-like protein - - - 0.000000001007 65.0
TLS3_k127_3061141_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 554.0
TLS3_k127_3061141_1 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000003458 115.0
TLS3_k127_3074068_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 321.0
TLS3_k127_3074068_1 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000002215 241.0
TLS3_k127_3074068_2 GGDEF domain - - - 0.000000000000000000000000000000000000000000003688 176.0
TLS3_k127_308863_0 Uncharacterized protein family, UPF0114 K03535 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 287.0
TLS3_k127_308863_1 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001074 240.0
TLS3_k127_308863_2 signal transduction histidine kinase - - - 0.000005201 55.0
TLS3_k127_3117698_0 PFAM Di-trans-poly-cis-decaprenylcistransferase-like K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 300.0
TLS3_k127_3117698_1 TIGRFAM Malto-oligosyltrehalose synthase K06044 - 5.4.99.15 0.0000000000000000000000000000000000000000000005847 170.0
TLS3_k127_3117698_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.00000000000002224 84.0
TLS3_k127_3117698_3 Hemerythrin HHE cation binding domain - - - 0.000000004514 64.0
TLS3_k127_3128428_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 0.0 1061.0
TLS3_k127_3128428_1 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 3.284e-200 638.0
TLS3_k127_3129052_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 5.541e-283 905.0
TLS3_k127_3129052_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 544.0
TLS3_k127_3137597_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 562.0
TLS3_k127_3137597_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 575.0
TLS3_k127_3137597_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 492.0
TLS3_k127_3137597_3 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 475.0
TLS3_k127_3137597_4 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 289.0
TLS3_k127_3137597_5 SprT-like family K02742 - - 0.0000000000000000000000000000000000000000000000005908 182.0
TLS3_k127_3137597_6 cellular response to DNA damage stimulus K07340 - - 0.000000000000000000000000000000000000000000004011 170.0
TLS3_k127_3137597_7 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000001578 163.0
TLS3_k127_3171566_0 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 347.0
TLS3_k127_3171566_1 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 318.0
TLS3_k127_3171566_2 Transposase - - - 0.0000000000000000000000000000000005034 133.0
TLS3_k127_3171566_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000003567 144.0
TLS3_k127_3171566_4 Transposase K07483 - - 0.0000000000000008993 81.0
TLS3_k127_3171566_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000001596 70.0
TLS3_k127_3171629_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 601.0
TLS3_k127_3171629_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 548.0
TLS3_k127_3171629_2 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 322.0
TLS3_k127_3171629_3 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 302.0
TLS3_k127_3171629_4 - - - - 0.0000000000000000000000000004962 113.0
TLS3_k127_3171629_5 COGs COG0790 FOG TPR repeat SEL1 subfamily K07126 - - 0.000000000000000001775 92.0
TLS3_k127_3171629_7 Uncharacterized protein conserved in bacteria (DUF2314) - - - 0.00006355 52.0
TLS3_k127_3186134_0 methyl-accepting chemotaxis protein (MCP) K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 565.0
TLS3_k127_3186134_1 Chemotaxis protein methyltransferase K00575 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006479,GO:0006807,GO:0006935,GO:0008022,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0008983,GO:0009605,GO:0009987,GO:0010340,GO:0016020,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0032991,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051998,GO:0071704,GO:0071944,GO:0098561,GO:0140096,GO:1901564 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 434.0
TLS3_k127_3186134_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411,K03412 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 295.0
TLS3_k127_3186134_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003003 251.0
TLS3_k127_3186134_4 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000001153 192.0
TLS3_k127_3186134_5 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000001681 173.0
TLS3_k127_3186134_6 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000005038 139.0
TLS3_k127_3187716_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.972e-196 620.0
TLS3_k127_3187716_1 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 476.0
TLS3_k127_3187716_2 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 434.0
TLS3_k127_3187716_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000003396 226.0
TLS3_k127_3187716_4 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000000005354 140.0
TLS3_k127_3187716_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K05553 - - 0.00000000000000000000000001886 114.0
TLS3_k127_321226_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 587.0
TLS3_k127_321226_1 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000001052 184.0
TLS3_k127_321226_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03408 - - 0.00000000000000000000000000000000000000000000001908 173.0
TLS3_k127_3251536_0 Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 322.0
TLS3_k127_3251536_1 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000001812 213.0
TLS3_k127_3251536_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000002261 113.0
TLS3_k127_3251536_3 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000003378 113.0
TLS3_k127_3251536_4 Glycosyltransferase like family 2 K16556 - - 0.0000000000000000482 84.0
TLS3_k127_3251536_5 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000008779 79.0
TLS3_k127_3251536_6 Transposase K07483 - - 0.000000000000000796 81.0
TLS3_k127_3251536_8 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000002599 66.0
TLS3_k127_3251536_9 PIN domain - - - 0.0001591 47.0
TLS3_k127_3255414_0 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 2.365e-270 842.0
TLS3_k127_3255414_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 9.118e-220 689.0
TLS3_k127_3255414_10 ORF6N domain - - - 0.0000000000000000000000000000000000000000001355 165.0
TLS3_k127_3255414_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 8.256e-213 670.0
TLS3_k127_3255414_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 530.0
TLS3_k127_3255414_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 508.0
TLS3_k127_3255414_5 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 390.0
TLS3_k127_3255414_6 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 332.0
TLS3_k127_3255414_7 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 300.0
TLS3_k127_3255414_9 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 239.0
TLS3_k127_329905_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 505.0
TLS3_k127_329905_1 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 437.0
TLS3_k127_329905_2 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 430.0
TLS3_k127_329905_3 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 310.0
TLS3_k127_329905_4 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007865 267.0
TLS3_k127_3314892_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1131.0
TLS3_k127_3314892_1 protein catabolic process K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.0 1017.0
TLS3_k127_3314892_10 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 365.0
TLS3_k127_3314892_11 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 349.0
TLS3_k127_3314892_12 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 334.0
TLS3_k127_3314892_13 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 325.0
TLS3_k127_3314892_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003014 270.0
TLS3_k127_3314892_15 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002967 199.0
TLS3_k127_3314892_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000001556 201.0
TLS3_k127_3314892_17 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000002349 192.0
TLS3_k127_3314892_18 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000251 186.0
TLS3_k127_3314892_19 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000008391 153.0
TLS3_k127_3314892_2 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 2.711e-280 864.0
TLS3_k127_3314892_20 Domain of unknown function (DUF4321) - - - 0.0000000000000000000000000000009574 124.0
TLS3_k127_3314892_21 ThiS family K03154 - - 0.0000000000000000009603 87.0
TLS3_k127_3314892_22 Uncharacterised protein family UPF0102 K07460 - - 0.0000000005157 63.0
TLS3_k127_3314892_3 O-methyltransferase activity K13571,K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119,6.3.1.19 6.813e-242 758.0
TLS3_k127_3314892_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.741e-235 734.0
TLS3_k127_3314892_5 tail specific protease K03797 - 3.4.21.102 2.489e-208 656.0
TLS3_k127_3314892_6 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 469.0
TLS3_k127_3314892_7 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 446.0
TLS3_k127_3314892_8 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 406.0
TLS3_k127_3314892_9 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 401.0
TLS3_k127_332407_0 phosphorelay signal transduction system K02481 - - 7.482e-227 709.0
TLS3_k127_332407_1 phosphorelay sensor kinase activity K02668,K10942 - 2.7.13.3 4.333e-219 688.0
TLS3_k127_332407_2 Cytochrome c K12263 - - 2.993e-198 621.0
TLS3_k127_332407_3 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005969 245.0
TLS3_k127_332407_4 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.0000000000000000000000000000000000000000000000000000000000003475 212.0
TLS3_k127_332407_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000006745 209.0
TLS3_k127_332407_7 - - - - 0.0000000000002071 79.0
TLS3_k127_3331390_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 8.288e-320 997.0
TLS3_k127_3331390_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 587.0
TLS3_k127_3331390_2 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 478.0
TLS3_k127_3331390_3 Associated with various cellular activities K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 441.0
TLS3_k127_3331390_4 Uncharacterised conserved protein (DUF2156) K01163,K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 438.0
TLS3_k127_3331390_5 glutathione transferase activity K00799 - 2.5.1.18 0.00000000000000000000000000006685 119.0
TLS3_k127_3331390_6 DUF167 K09131 - - 0.00000000000000000001644 95.0
TLS3_k127_3346728_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 9.439e-223 696.0
TLS3_k127_3346728_1 Belongs to the sirtuin family. Class K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 379.0
TLS3_k127_3346728_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 342.0
TLS3_k127_3346728_3 COG0659 Sulfate permease and related transporters (MFS K01673,K03321 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 312.0
TLS3_k127_3346728_4 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005445 283.0
TLS3_k127_3346728_5 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K07025 - - 0.0000000000000000000000000000000000000000000004076 175.0
TLS3_k127_3346728_6 - - - - 0.00000000000000000000000000000000000000007938 161.0
TLS3_k127_3376118_0 Glycosyltransferase family 17 K00737 - 2.4.1.144 0.000000000000000000000000000000000000000000000000000266 197.0
TLS3_k127_3376118_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000007459 183.0
TLS3_k127_3376118_2 Glycosyltransferase family 17 K00737 - 2.4.1.144 0.0000000000000000000000000000000000000000001477 164.0
TLS3_k127_3420189_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.0 1358.0
TLS3_k127_34202_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 473.0
TLS3_k127_34202_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 345.0
TLS3_k127_34202_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 273.0
TLS3_k127_34202_3 protein homooligomerization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000823 243.0
TLS3_k127_34202_4 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000000000000000000000000000000000001048 145.0
TLS3_k127_3422210_0 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 358.0
TLS3_k127_3422210_1 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 283.0
TLS3_k127_3422210_2 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000001916 243.0
TLS3_k127_3422210_3 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.000003682 48.0
TLS3_k127_3451570_0 DNA topoisomerase II activity K03167 - 5.99.1.3 0.0 1025.0
TLS3_k127_3451570_1 Type III restriction enzyme res subunit - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 8.34e-254 791.0
TLS3_k127_3451570_2 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 1.019e-221 689.0
TLS3_k127_3451570_3 exonuclease activity K16899 - 3.6.4.12 8.592e-212 691.0
TLS3_k127_3451570_4 Thioredoxin domain - - - 0.00000000000000000000000000000000000000004032 153.0
TLS3_k127_3451570_5 Domain of unknown function (DUF3817) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000004852 97.0
TLS3_k127_3451570_6 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000001628 81.0
TLS3_k127_3452193_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 414.0
TLS3_k127_3452193_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001372 229.0
TLS3_k127_3452193_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000003881 187.0
TLS3_k127_3452193_4 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.0000000000000000000000000000000000000000002205 166.0
TLS3_k127_3452193_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000001208 148.0
TLS3_k127_3452193_6 response regulator K03413 - - 0.00000000000000000000000005608 110.0
TLS3_k127_3452193_7 WD40 domain protein beta Propeller K03641 - - 0.000000000000000000000000713 118.0
TLS3_k127_3452193_8 His Kinase A (phosphoacceptor) domain - - - 0.0000044 55.0
TLS3_k127_3452193_9 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K02479 - - 0.00004046 47.0
TLS3_k127_3461524_0 Rubrerythrin K22405 - 1.6.3.4 0.0 1206.0
TLS3_k127_3461524_1 Iron-sulfur cluster-binding domain - - - 7.257e-273 843.0
TLS3_k127_3461524_2 Ftsk_gamma K03466 - - 9.031e-260 812.0
TLS3_k127_3461524_3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 388.0
TLS3_k127_3461524_4 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 306.0
TLS3_k127_3461524_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000001152 93.0
TLS3_k127_3464308_0 Heat shock 70 kDa protein K04043 - - 3.062e-242 755.0
TLS3_k127_3481808_1 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 307.0
TLS3_k127_3511296_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 1.004e-262 814.0
TLS3_k127_3511296_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 347.0
TLS3_k127_3511296_2 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000000000000000000006484 220.0
TLS3_k127_3511296_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000001653 150.0
TLS3_k127_3515036_0 peptidyl-tyrosine sulfation - - - 5.182e-196 629.0
TLS3_k127_3515036_2 OsmC-like protein - - - 0.0000000108 56.0
TLS3_k127_3546790_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000001122 179.0
TLS3_k127_3546790_1 response regulator - - - 0.0000000001718 74.0
TLS3_k127_3553502_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 378.0
TLS3_k127_3553502_1 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 336.0
TLS3_k127_3553502_2 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000002925 244.0
TLS3_k127_3553502_3 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000005078 129.0
TLS3_k127_3587677_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 355.0
TLS3_k127_3587677_1 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000009532 105.0
TLS3_k127_3597062_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.0 1049.0
TLS3_k127_3597062_1 spermidine synthase activity K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 401.0
TLS3_k127_3597062_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000009147 224.0
TLS3_k127_3620161_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 469.0
TLS3_k127_3620161_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 346.0
TLS3_k127_3620161_2 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 286.0
TLS3_k127_3620161_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000002502 191.0
TLS3_k127_3620161_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000007326 155.0
TLS3_k127_3620161_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000006879 100.0
TLS3_k127_3628174_0 PAS fold - - - 8.243e-197 639.0
TLS3_k127_3628174_1 Heme oxygenase - - - 0.00000000000000000000000000001053 126.0
TLS3_k127_3628174_2 photoreceptor activity - - - 0.00000000000000000000001243 107.0
TLS3_k127_3628174_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000006683 83.0
TLS3_k127_3629661_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000008216 236.0
TLS3_k127_3629661_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.000000000000000000000000000000000000000000000000000000001263 203.0
TLS3_k127_3629661_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.00000000000000000000000000000000000000004277 155.0
TLS3_k127_36414_0 Proteasomal ATPase OB/ID domain K13527 - - 1.048e-210 662.0
TLS3_k127_36414_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 530.0
TLS3_k127_36414_2 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 447.0
TLS3_k127_36414_3 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 387.0
TLS3_k127_36414_4 Evidence 5 No homology to any previously reported sequences K02450,K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 296.0
TLS3_k127_36414_5 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000004114 261.0
TLS3_k127_36414_7 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000004392 184.0
TLS3_k127_36414_8 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000000000000000000000000000000000000000009861 182.0
TLS3_k127_36414_9 Protein of unknown function (DUF3574) - - - 0.000000000000000000000000000000007578 132.0
TLS3_k127_3648290_0 peptidyl-tyrosine sulfation - - - 5.479e-203 685.0
TLS3_k127_3648290_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 529.0
TLS3_k127_3648290_10 Mitochondrial biogenesis AIM24 - - - 0.00000000001161 66.0
TLS3_k127_3648290_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 394.0
TLS3_k127_3648290_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 317.0
TLS3_k127_3648290_4 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 323.0
TLS3_k127_3648290_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 309.0
TLS3_k127_3648290_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 289.0
TLS3_k127_3648290_7 protein transport across the cell outer membrane K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007045 258.0
TLS3_k127_3648290_9 phosphorelay signal transduction system K02667 - - 0.00000000000000000005867 89.0
TLS3_k127_3648838_0 nitric oxide reductase activity K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 412.0
TLS3_k127_3648838_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 319.0
TLS3_k127_3648838_2 NAD(P)H-binding - - - 0.00000000001849 66.0
TLS3_k127_3648838_3 hydrolase activity, acting on ester bonds - - - 0.0000000007156 62.0
TLS3_k127_3662072_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 4.208e-228 713.0
TLS3_k127_3662072_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007364 263.0
TLS3_k127_3662072_2 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004135 244.0
TLS3_k127_3662072_3 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000000000000000000000000000000000004904 237.0
TLS3_k127_3662072_4 nitric oxide dioxygenase activity - - - 0.000000000000000000000000000000001739 134.0
TLS3_k127_3666314_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 517.0
TLS3_k127_3666314_1 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 460.0
TLS3_k127_3666314_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 402.0
TLS3_k127_3666314_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000001371 261.0
TLS3_k127_3666314_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000007825 250.0
TLS3_k127_3666314_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000004198 130.0
TLS3_k127_3676977_0 TIGRFAM Malto-oligosyltrehalose synthase K06044 - 5.4.99.15 2.248e-310 978.0
TLS3_k127_3676977_1 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 1.623e-259 810.0
TLS3_k127_3676977_12 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000009414 53.0
TLS3_k127_3676977_13 HicA toxin of bacterial toxin-antitoxin, - - - 0.00002493 50.0
TLS3_k127_3676977_2 Glycosyl hydrolases family 15 - - - 4.776e-242 761.0
TLS3_k127_3676977_3 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 4.832e-237 751.0
TLS3_k127_3676977_4 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000905 440.0
TLS3_k127_3676977_5 Glycosyl transferase family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 366.0
TLS3_k127_3676977_6 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000006374 281.0
TLS3_k127_3676977_7 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000004155 241.0
TLS3_k127_3676977_8 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000194 134.0
TLS3_k127_3676977_9 - - - - 0.000000000000000000001012 99.0
TLS3_k127_3722415_0 PD-(D/E)XK nuclease superfamily - - - 1.571e-302 957.0
TLS3_k127_3722415_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 382.0
TLS3_k127_3722415_2 - K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000002051 201.0
TLS3_k127_3722415_3 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000343 154.0
TLS3_k127_3722415_4 gas vesicle protein - - - 0.000000000000001355 80.0
TLS3_k127_373327_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 398.0
TLS3_k127_373327_1 Protein of unknown function (DUF1565) - - - 0.00000000000000000008487 103.0
TLS3_k127_3741190_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001588 258.0
TLS3_k127_3741190_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000001299 239.0
TLS3_k127_3741190_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000001203 203.0
TLS3_k127_3741190_3 phosphorelay signal transduction system - - - 0.000000000000000000000000000001178 123.0
TLS3_k127_3741190_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000002572 130.0
TLS3_k127_3744772_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007366 270.0
TLS3_k127_3744772_1 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000004744 191.0
TLS3_k127_3744772_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000322 57.0
TLS3_k127_3760784_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.372e-256 795.0
TLS3_k127_3760784_1 RNA signal recognition particle 4.5S RNA - - - 0.00000000000000000000000000000000000000000000000000005207 189.0
TLS3_k127_3760784_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000006812 165.0
TLS3_k127_3760784_3 Protein conserved in bacteria K18480 - - 0.00000000000000000000000000000000000000000846 162.0
TLS3_k127_3760784_4 Transglycosylase SLT domain - - - 0.00000000000000000000000000000002278 135.0
TLS3_k127_3760784_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000756 82.0
TLS3_k127_3760784_6 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067,K06192 - - 0.0000000002588 62.0
TLS3_k127_3760784_7 Protein of unknown function (DUF1059) - - - 0.00002593 48.0
TLS3_k127_3767472_0 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 492.0
TLS3_k127_3767472_1 Bacterial regulatory protein, Fis family K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 423.0
TLS3_k127_3767472_2 phosphorelay sensor kinase activity K07708,K07710,K10942 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 376.0
TLS3_k127_3767472_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 301.0
TLS3_k127_3767472_4 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000000000001099 233.0
TLS3_k127_3767472_5 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000000000000000000004111 177.0
TLS3_k127_3767472_6 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000000000000000049 110.0
TLS3_k127_3768878_0 Histidine kinase K07638 - 2.7.13.3 3.084e-290 909.0
TLS3_k127_3768878_1 Histidine kinase K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 424.0
TLS3_k127_3768878_2 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008829 302.0
TLS3_k127_3768878_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003373 250.0
TLS3_k127_3768878_4 protein disulfide oxidoreductase activity K07390 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000102 201.0
TLS3_k127_3768878_5 Belongs to the BolA IbaG family K05527,K22066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0019538,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051604,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097428,GO:0097659,GO:0106035,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.00000000000000000000000001732 111.0
TLS3_k127_3773634_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000000000000000000007441 198.0
TLS3_k127_3773634_1 Bacterial PH domain - - - 0.00000000000000000000000000000002739 132.0
TLS3_k127_3773634_2 Dodecin K09165 - - 0.00000000000000000003649 96.0
TLS3_k127_3773634_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000009883 88.0
TLS3_k127_3773634_4 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000001619 63.0
TLS3_k127_3773985_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 9.956e-250 774.0
TLS3_k127_3773985_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.405e-222 705.0
TLS3_k127_3773985_10 protein secretion K03116 - - 0.00000000000000000000000000000000000009559 147.0
TLS3_k127_3773985_11 deoxyhypusine monooxygenase activity K05386 - - 0.000000000001374 74.0
TLS3_k127_3773985_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K10936,K16079 - - 0.0001137 51.0
TLS3_k127_3773985_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 604.0
TLS3_k127_3773985_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 417.0
TLS3_k127_3773985_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 389.0
TLS3_k127_3773985_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 354.0
TLS3_k127_3773985_6 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000000000000000000000009327 237.0
TLS3_k127_3773985_7 PilZ domain K02676 - - 0.00000000000000000000000000000000000000000000000000000000000000003245 227.0
TLS3_k127_3773985_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000003883 166.0
TLS3_k127_3773985_9 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000424 165.0
TLS3_k127_3774217_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000001024 244.0
TLS3_k127_3774217_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000008618 138.0
TLS3_k127_3774217_2 glyoxalase III activity - - - 0.00000000000000000001063 93.0
TLS3_k127_3790537_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 449.0
TLS3_k127_3790537_1 Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 389.0
TLS3_k127_3790537_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 338.0
TLS3_k127_3790537_3 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000001279 171.0
TLS3_k127_3790537_4 Adenosylcobinamide amidohydrolase - - - 0.00000000000000000000000006011 117.0
TLS3_k127_3790537_5 - - - - 0.000000004561 58.0
TLS3_k127_385280_0 Evidence 4 Homologs of previously reported genes of K07114,K08309 - - 3.869e-253 803.0
TLS3_k127_385280_1 Protein conserved in bacteria K20920 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 343.0
TLS3_k127_385280_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007249 250.0
TLS3_k127_3883182_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000004572 191.0
TLS3_k127_3900281_0 response regulator K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006604 278.0
TLS3_k127_3900281_1 Histidine kinase K07683 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000007771 258.0
TLS3_k127_3900281_2 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.00000000000000000001928 94.0
TLS3_k127_3900281_3 amino acid - - - 0.000001602 51.0
TLS3_k127_3901933_0 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 357.0
TLS3_k127_390859_0 Lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 303.0
TLS3_k127_390859_1 Saccharopine dehydrogenase NADP binding domain K00290 - 1.5.1.7 0.000000008484 63.0
TLS3_k127_3944194_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006871 244.0
TLS3_k127_3944194_1 efflux transmembrane transporter activity K03287 - - 0.00000000000000000000000000000000000004451 145.0
TLS3_k127_3944194_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000008473 103.0
TLS3_k127_3944194_3 efflux transmembrane transporter activity K03287 - - 0.000006211 52.0
TLS3_k127_3969710_0 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 366.0
TLS3_k127_3969710_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000009318 213.0
TLS3_k127_3969710_2 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.0000000000000000000000000000000005018 137.0
TLS3_k127_3998327_0 Protein involved in outer membrane biogenesis - - - 1.796e-237 762.0
TLS3_k127_3998327_1 Belongs to the 'phage' integrase family - - - 0.0000000000004289 72.0
TLS3_k127_4008093_0 - - - - 0.00000000000000000000000000000000000000000000000000009271 192.0
TLS3_k127_4008093_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.0001966 51.0
TLS3_k127_4008093_2 - - - - 0.0003231 53.0
TLS3_k127_4020762_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.855e-278 865.0
TLS3_k127_4020762_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 390.0
TLS3_k127_4020762_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000007058 182.0
TLS3_k127_4020762_3 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000002218 163.0
TLS3_k127_4020762_4 LysR substrate binding domain K13794,K19338 - - 0.00000000000000000000000000001314 130.0
TLS3_k127_4020762_5 Transcriptional regulator - - - 0.000006735 53.0
TLS3_k127_4035446_0 drug transmembrane transporter activity K03327 - - 3.406e-215 674.0
TLS3_k127_4035446_1 COG0659 Sulfate permease and related transporters (MFS K01673,K03321 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 605.0
TLS3_k127_4035446_2 - K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 596.0
TLS3_k127_4035446_3 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 524.0
TLS3_k127_4035446_4 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000419 240.0
TLS3_k127_4035446_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000008322 233.0
TLS3_k127_4052285_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 401.0
TLS3_k127_4052285_1 Belongs to the TPP enzyme family K00156 - 1.2.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 372.0
TLS3_k127_4052285_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002474 279.0
TLS3_k127_4052285_3 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009602 249.0
TLS3_k127_4052285_4 modulation by symbiont of host adenylate cyclase-mediated signal transduction K03775 - 5.2.1.8 0.000000000000001006 86.0
TLS3_k127_4057653_0 IMP dehydrogenase activity K09137 - - 0.0000000000000000000000000000000000000001644 154.0
TLS3_k127_4057653_1 Nodulation protein S (NodS) - - - 0.0000000000000000000000192 109.0
TLS3_k127_4057653_2 PFAM regulatory protein LuxR - - - 0.000000000000005105 81.0
TLS3_k127_4057653_3 Pectate lyase K21606 - 3.2.1.202 0.00000000000002718 83.0
TLS3_k127_4057653_4 Crp-like helix-turn-helix domain - - - 0.000000006512 61.0
TLS3_k127_4062935_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.105e-259 806.0
TLS3_k127_4062935_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007561 268.0
TLS3_k127_4072686_0 response regulator K02282 - - 0.000000000000000000000000000000000000000000000000000000000000002164 225.0
TLS3_k127_4072686_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000001648 199.0
TLS3_k127_4072686_2 peptidase - - - 0.00000000000001706 79.0
TLS3_k127_4072942_0 TonB-dependent receptor - - - 0.0 1060.0
TLS3_k127_4072942_1 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 1.755e-229 724.0
TLS3_k127_4072942_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000004779 86.0
TLS3_k127_4072942_2 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 1.93e-217 681.0
TLS3_k127_4072942_3 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 439.0
TLS3_k127_4072942_4 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 381.0
TLS3_k127_4072942_5 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005759 275.0
TLS3_k127_4072942_6 response to nickel cation K07722 GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016151,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032991,GO:0032993,GO:0042802,GO:0043167,GO:0043169,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071840,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000001183 229.0
TLS3_k127_4072942_8 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000003646 135.0
TLS3_k127_4072942_9 HupE / UreJ protein - - - 0.0000000000000000000009234 99.0
TLS3_k127_4075400_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 469.0
TLS3_k127_4098732_0 Aminotransferase class I and II K10206 - 2.6.1.83 5.46e-243 752.0
TLS3_k127_4098732_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 458.0
TLS3_k127_4098732_11 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000002075 155.0
TLS3_k127_4098732_14 transcription regulator containing HTH domain K18831 - - 0.00000000000000000001393 93.0
TLS3_k127_4098732_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 363.0
TLS3_k127_4098732_3 methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 327.0
TLS3_k127_4098732_5 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004236 273.0
TLS3_k127_4098732_6 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003744 256.0
TLS3_k127_4098732_9 Protein conserved in bacteria K16785 - - 0.0000000000000000000000000000000000000000000000001791 183.0
TLS3_k127_412146_0 glutamate dehydrogenase [NAD(P)+] activity K00261,K00262 - 1.4.1.3,1.4.1.4 2.05e-224 700.0
TLS3_k127_412146_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 584.0
TLS3_k127_412146_2 Proto-chlorophyllide reductase 57 kD subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 498.0
TLS3_k127_412146_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000998 369.0
TLS3_k127_412146_6 lipoyl(octanoyl) transferase activity K03644,K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181,2.8.1.8 0.00000000000000000000000000000000000000001248 160.0
TLS3_k127_4151314_0 Bilirubin oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 423.0
TLS3_k127_4151314_1 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000001001 241.0
TLS3_k127_4151314_2 SCO1/SenC - - - 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
TLS3_k127_4153278_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 419.0
TLS3_k127_4153278_1 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000134 243.0
TLS3_k127_4153278_2 Acyltransferase family - - - 0.000000000000000000000000000000000007071 146.0
TLS3_k127_4203774_0 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 397.0
TLS3_k127_4203774_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006485 289.0
TLS3_k127_4203774_2 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004816 259.0
TLS3_k127_4203774_3 response regulator K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001029 250.0
TLS3_k127_4203774_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000004237 132.0
TLS3_k127_4203774_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000006023 67.0
TLS3_k127_4203774_6 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000001375 63.0
TLS3_k127_4209346_0 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 601.0
TLS3_k127_4209346_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 328.0
TLS3_k127_4209346_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03408 - - 0.00000000000000000000000000305 111.0
TLS3_k127_4246237_0 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 385.0
TLS3_k127_4246237_1 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 310.0
TLS3_k127_4246237_3 acyl carrier protein K02078 - - 0.00000000000000000000001015 103.0
TLS3_k127_4246237_4 DDE domain - - - 0.0000000000000000000004112 98.0
TLS3_k127_4246237_5 AMP-binding enzyme - - - 0.000000000000000004109 90.0
TLS3_k127_4246237_6 UPF0391 membrane protein - - - 0.000000000000001769 77.0
TLS3_k127_4275141_0 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 526.0
TLS3_k127_4275141_2 transport of arsenical compounds across the membrane (export) arsenic resistance by an export mechanism. responsible for the translocation of the substrate across the membrane K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 306.0
TLS3_k127_4275141_3 Peptidase M15 K02395 - - 0.00000000000000000000000000000000000000000000000000000004287 205.0
TLS3_k127_4275141_4 phosphorelay signal transduction system K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000002406 190.0
TLS3_k127_4278005_0 Conserved carboxylase domain K01960 - 6.4.1.1 2.177e-318 981.0
TLS3_k127_4278005_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00322,K00382 - 1.6.1.1,1.8.1.4 4.388e-220 691.0
TLS3_k127_4278005_2 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 379.0
TLS3_k127_4278005_3 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 354.0
TLS3_k127_4278005_4 thioredoxin peroxidase activity K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 308.0
TLS3_k127_4337530_0 Putative Ig domain - - - 0.000000000000001229 84.0
TLS3_k127_4348218_0 Type ii secretion system protein e K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 561.0
TLS3_k127_4348218_1 type II secretion system protein K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000006304 233.0
TLS3_k127_4348218_2 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000004625 186.0
TLS3_k127_4348218_3 PFAM Type II secretion system F K12511 - - 0.0003634 47.0
TLS3_k127_4357014_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 410.0
TLS3_k127_4357014_1 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000378 247.0
TLS3_k127_4357014_10 PRC-barrel domain - - - 0.0005313 51.0
TLS3_k127_4357014_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000001199 151.0
TLS3_k127_4357014_3 Domain of Unknown Function (DUF326) - - - 0.000000000000000000000000004393 115.0
TLS3_k127_4357014_4 PRC-barrel domain - - - 0.000000000000000000000000007299 116.0
TLS3_k127_4357014_5 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000003301 74.0
TLS3_k127_4357014_6 UPF0391 membrane protein - - - 0.0000000000824 64.0
TLS3_k127_4357014_7 Outer Membrane Lipoprotein K07285 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802 - 0.000002418 57.0
TLS3_k127_4357014_8 AhpC/TSA family K03386 - 1.11.1.15 0.000005206 49.0
TLS3_k127_4357014_9 Protein of unknown function (DUF2934) - - - 0.0001037 48.0
TLS3_k127_4385910_0 PFAM short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 408.0
TLS3_k127_4385910_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 416.0
TLS3_k127_4385910_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000004612 234.0
TLS3_k127_4400672_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1078.0
TLS3_k127_4400672_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 531.0
TLS3_k127_4400672_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 492.0
TLS3_k127_4400672_3 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 488.0
TLS3_k127_4400672_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 457.0
TLS3_k127_4400672_5 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000002728 235.0
TLS3_k127_4400672_6 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000000000000000000000000000000000000001326 234.0
TLS3_k127_4400672_7 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000000000000000000004717 218.0
TLS3_k127_4400672_8 response regulator K07814 - - 0.00000000000000000000000004683 110.0
TLS3_k127_4409322_0 Evidence 2b Function of strongly homologous gene K01740,K03430,K05306,K09469 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 566.0
TLS3_k127_4409322_1 Belongs to the TPP enzyme family K09459 - 4.1.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 355.0
TLS3_k127_4409322_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008592 277.0
TLS3_k127_4409322_5 Nucleotidyl transferase - - - 0.000000000000000000000000009522 109.0
TLS3_k127_4425733_0 amino acid - - - 1.182e-237 742.0
TLS3_k127_4425733_1 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 1.954e-234 745.0
TLS3_k127_4425733_10 anaphase-promoting complex-dependent catabolic process - - - 0.00000000000000000000000000000000000000000000000000001714 195.0
TLS3_k127_4425733_11 PAP2 superfamily K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000003116 202.0
TLS3_k127_4425733_12 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000001368 199.0
TLS3_k127_4425733_13 lipid-A-disaccharide synthase activity - - - 0.000000000000000000000000000000000000002511 148.0
TLS3_k127_4425733_14 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.000000000000000000000000000006384 121.0
TLS3_k127_4425733_16 - - - - 0.0000000001216 69.0
TLS3_k127_4425733_18 - K18829 - - 0.00001581 48.0
TLS3_k127_4425733_2 Arginase family K01480 - 3.5.3.11 1.739e-212 663.0
TLS3_k127_4425733_3 acr, cog1565 K00412,K00971,K02275,K02389,K03177,K17624 - 1.9.3.1,2.7.7.13,3.2.1.97,5.4.99.25 3.006e-209 659.0
TLS3_k127_4425733_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 8.739e-203 648.0
TLS3_k127_4425733_5 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 554.0
TLS3_k127_4425733_6 PFAM Mo-dependent nitrogenase K00232 - 1.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 482.0
TLS3_k127_4425733_7 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 342.0
TLS3_k127_4425733_8 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000003915 231.0
TLS3_k127_4425733_9 peptide catabolic process - - - 0.000000000000000000000000000000000000000000000000000000001077 211.0
TLS3_k127_4445387_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 557.0
TLS3_k127_4445387_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 458.0
TLS3_k127_4445387_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 434.0
TLS3_k127_4445387_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 302.0
TLS3_k127_4445387_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005141 278.0
TLS3_k127_4445387_5 LmbE homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001843 269.0
TLS3_k127_4445387_6 WbqC-like protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000001053 234.0
TLS3_k127_4445387_7 - - - - 0.000000000000000000000000000000000000000000000000000000000001055 230.0
TLS3_k127_4445387_8 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000001201 196.0
TLS3_k127_4445387_9 Methyltransferase domain - - - 0.000000000000000000006522 103.0
TLS3_k127_4453422_0 Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 326.0
TLS3_k127_4453422_1 - - - - 0.000000000000000000000000002044 116.0
TLS3_k127_4453422_3 transposase activity K07483 - - 0.0000000000003203 74.0
TLS3_k127_4453422_5 - K21495 - - 0.0000000007831 61.0
TLS3_k127_4464753_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1189.0
TLS3_k127_4464753_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 2.034e-227 714.0
TLS3_k127_4464753_11 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000004534 181.0
TLS3_k127_4464753_12 spermidine synthase activity K00797 - 2.5.1.16 0.0000000000000000000000000000000000000001513 153.0
TLS3_k127_4464753_2 Evidence 4 Homologs of previously reported genes of - - - 4.242e-225 705.0
TLS3_k127_4464753_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 594.0
TLS3_k127_4464753_4 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 489.0
TLS3_k127_4464753_5 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 420.0
TLS3_k127_4464753_6 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 398.0
TLS3_k127_4464753_7 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 383.0
TLS3_k127_4464753_8 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 371.0
TLS3_k127_4466048_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 600.0
TLS3_k127_4466048_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 526.0
TLS3_k127_4466048_2 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009309 268.0
TLS3_k127_4469261_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1313.0
TLS3_k127_4469261_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.34e-244 761.0
TLS3_k127_4469261_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 288.0
TLS3_k127_4469261_11 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000001538 216.0
TLS3_k127_4469261_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.189e-230 715.0
TLS3_k127_4469261_3 rRNA (guanine-N2-)-methyltransferase activity K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.304,2.1.1.333 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 577.0
TLS3_k127_4469261_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 563.0
TLS3_k127_4469261_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 424.0
TLS3_k127_4469261_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 409.0
TLS3_k127_4469261_7 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 394.0
TLS3_k127_4469261_8 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 362.0
TLS3_k127_4469261_9 Tetratricopeptide repeat K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 306.0
TLS3_k127_450098_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 6.271e-310 960.0
TLS3_k127_450098_1 anaerobic respiration K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 572.0
TLS3_k127_450098_10 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.000000004646 61.0
TLS3_k127_450098_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 361.0
TLS3_k127_450098_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004515 280.0
TLS3_k127_450098_4 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007523 243.0
TLS3_k127_450098_5 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000008039 252.0
TLS3_k127_450098_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000007433 207.0
TLS3_k127_450098_7 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000457 202.0
TLS3_k127_450098_8 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000000001597 171.0
TLS3_k127_450098_9 membrane - - - 0.00000000000000000000000000000000000000001218 159.0
TLS3_k127_4505090_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 549.0
TLS3_k127_4505090_1 Belongs to the 'phage' integrase family - - - 0.0000000001102 65.0
TLS3_k127_4508970_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1085.0
TLS3_k127_4508970_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.917e-261 833.0
TLS3_k127_4508970_10 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 484.0
TLS3_k127_4508970_11 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 386.0
TLS3_k127_4508970_12 branched-chain-amino-acid transaminase activity K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 339.0
TLS3_k127_4508970_14 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 321.0
TLS3_k127_4508970_15 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002065 242.0
TLS3_k127_4508970_18 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000000000002463 209.0
TLS3_k127_4508970_19 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000005914 188.0
TLS3_k127_4508970_2 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.652e-247 781.0
TLS3_k127_4508970_20 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000000001857 185.0
TLS3_k127_4508970_21 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000000000000000000000000000000000000005274 182.0
TLS3_k127_4508970_22 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000174 157.0
TLS3_k127_4508970_23 Protein conserved in bacteria K09764 - - 0.00000000000000000000000000000000377 130.0
TLS3_k127_4508970_24 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000001295 134.0
TLS3_k127_4508970_3 Aminotransferase class I and II K14261 - - 9.486e-240 744.0
TLS3_k127_4508970_4 Homoserine dehydrogenase K00003 - 1.1.1.3 5.843e-215 674.0
TLS3_k127_4508970_5 Participates in both transcription termination and antitermination K02600 - - 8.451e-213 664.0
TLS3_k127_4508970_6 ACT domain K00928 - 2.7.2.4 2.531e-212 665.0
TLS3_k127_4508970_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 1.481e-210 666.0
TLS3_k127_4508970_8 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 583.0
TLS3_k127_4508970_9 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 547.0
TLS3_k127_4521852_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 513.0
TLS3_k127_4521852_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 337.0
TLS3_k127_4521852_2 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000001052 227.0
TLS3_k127_4521852_3 Major Facilitator - - - 0.000000000000000000000000000000000000000001876 172.0
TLS3_k127_4521852_4 Major Facilitator Superfamily K08177 - - 0.00000000000000000001149 100.0
TLS3_k127_453408_0 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 1.128e-216 686.0
TLS3_k127_453408_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 481.0
TLS3_k127_453408_10 FAD dependent oxidoreductase - - - 0.0000000001636 63.0
TLS3_k127_453408_11 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K09471 - - 0.000004376 52.0
TLS3_k127_453408_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001373 256.0
TLS3_k127_453408_3 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000001331 198.0
TLS3_k127_453408_4 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000004696 192.0
TLS3_k127_453408_5 Sulphur transport K07112 - - 0.00000000000000000000000000000000002836 143.0
TLS3_k127_453408_6 FAD dependent oxidoreductase - - - 0.000000000000000000000002546 104.0
TLS3_k127_453408_7 BON domain K04065 - - 0.000000000000000000000009416 108.0
TLS3_k127_453408_9 Beta/Gamma crystallin - - - 0.00000000004335 68.0
TLS3_k127_4534144_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 455.0
TLS3_k127_4534144_1 Protein of unknown function (DUF1264) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 326.0
TLS3_k127_4534144_2 phosphorelay signal transduction system K02535 - 3.5.1.108 0.00000000000000000000000000000000007527 137.0
TLS3_k127_4534144_4 DNA excision K02806 - - 0.0000000000000000000000000000008366 124.0
TLS3_k127_4534144_5 Histidine kinase-like ATPases - - - 0.0000000000000000006304 94.0
TLS3_k127_4547261_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.425e-242 756.0
TLS3_k127_4547261_1 SMART Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 302.0
TLS3_k127_4547261_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000002017 236.0
TLS3_k127_4547261_3 SMART Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000008147 181.0
TLS3_k127_4570244_0 methyltransferase activity K00569 - 2.1.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 307.0
TLS3_k127_4570244_1 - - - - 0.0000000003607 72.0
TLS3_k127_4592023_0 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000009912 142.0
TLS3_k127_4592023_1 Peptidase S24-like - - - 0.00000000003768 68.0
TLS3_k127_4592023_3 IMP dehydrogenase activity K09137 - - 0.0005491 44.0
TLS3_k127_4594564_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000001094 203.0
TLS3_k127_4594564_1 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000000000000000000000005583 111.0
TLS3_k127_4594564_2 response regulator, receiver K02479 - - 0.0000000000000000000441 94.0
TLS3_k127_4594564_3 NAD(P)H-binding K07118 - - 0.00000000000000009258 81.0
TLS3_k127_4594564_4 Transport permease protein K01992 - - 0.000000001484 68.0
TLS3_k127_4594564_5 c-di-gmp phosphodiesterase - - - 0.0003504 43.0
TLS3_k127_4595209_0 Domain of unknown function DUF21 K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 370.0
TLS3_k127_4595209_1 - - - - 0.00000000000000000000000000000000000000000000009334 176.0
TLS3_k127_4607557_0 - K01992 - - 1.304e-224 706.0
TLS3_k127_4607557_1 ATPase activity K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 473.0
TLS3_k127_4607557_2 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 371.0
TLS3_k127_4607557_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 359.0
TLS3_k127_4607557_4 peptidoglycan binding K03642 - - 0.0000000000000000000000000000000000000000000000009625 183.0
TLS3_k127_4648346_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 603.0
TLS3_k127_4648346_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 605.0
TLS3_k127_4648346_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 574.0
TLS3_k127_4648346_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001401 263.0
TLS3_k127_4648346_4 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000000000000005483 181.0
TLS3_k127_4648346_5 Putative regulatory protein - - - 0.000000000000000000000000003827 114.0
TLS3_k127_465986_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 2.599e-235 741.0
TLS3_k127_4669829_0 Amino acid permease K03294 - - 1.704e-233 730.0
TLS3_k127_4669829_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 501.0
TLS3_k127_4669829_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 471.0
TLS3_k127_4669829_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 331.0
TLS3_k127_4669829_4 Phosphoserine phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 292.0
TLS3_k127_4669829_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000004936 143.0
TLS3_k127_4672042_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 389.0
TLS3_k127_4672042_1 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 293.0
TLS3_k127_4672042_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000005236 159.0
TLS3_k127_4672042_3 Dicarboxylate transport - - - 0.000000000000000000000000005079 129.0
TLS3_k127_4672042_4 protein conserved in bacteria K09978 - - 0.00000000000000000004086 93.0
TLS3_k127_4672042_5 Lipoprotein - - - 0.00000000000000009904 81.0
TLS3_k127_4680814_0 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 428.0
TLS3_k127_4680814_1 - - - - 0.000000000000000000000001556 114.0
TLS3_k127_4680814_2 phosphorelay signal transduction system K02535 - 3.5.1.108 0.00006381 46.0
TLS3_k127_4680814_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0006689 46.0
TLS3_k127_4681687_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437,K03501 - 2.1.1.170,2.1.1.185 0.000000000000000000000000000000000000000000000000000000237 205.0
TLS3_k127_4681687_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000002774 165.0
TLS3_k127_4681687_2 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000009893 159.0
TLS3_k127_4681687_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.000000007952 59.0
TLS3_k127_4690969_0 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K20997 - - 1.23e-210 663.0
TLS3_k127_4690969_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 366.0
TLS3_k127_4690969_2 PFAM Glycosyl transferase family 2 K12992 - - 0.000000000000000000000000000000000000000000000000000000000002925 214.0
TLS3_k127_4719652_0 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 567.0
TLS3_k127_4719652_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 434.0
TLS3_k127_4719652_2 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 362.0
TLS3_k127_4719652_3 PFAM ABC transporter related K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 304.0
TLS3_k127_4719652_4 ABC-type glycine betaine transport system K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 308.0
TLS3_k127_4719652_5 glycine betaine transport K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005579 259.0
TLS3_k127_4719652_6 PFAM Aminotransferase class-V K04127,K11325 - 5.1.1.17 0.00000000000000000000000000000000002834 150.0
TLS3_k127_4719652_7 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000004364 133.0
TLS3_k127_4741603_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 538.0
TLS3_k127_4741603_1 Magnesium transport protein CorA K03284 GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 300.0
TLS3_k127_4741603_2 inositol monophosphate 1-phosphatase activity K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000001601 260.0
TLS3_k127_4769007_0 TIGRFAM TRAP transporter, DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 532.0
TLS3_k127_4769007_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000004591 224.0
TLS3_k127_4769007_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000005076 178.0
TLS3_k127_4769007_3 - - - - 0.0000000000000000000000000000000000000000004574 168.0
TLS3_k127_4769007_4 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000003466 96.0
TLS3_k127_4795378_0 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001287 280.0
TLS3_k127_4795378_1 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003235 256.0
TLS3_k127_4795378_2 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000091 193.0
TLS3_k127_4795378_3 - - - - 0.00000000000000000000000000000000121 142.0
TLS3_k127_4795378_5 PFAM O-methyltransferase - - - 0.00001726 51.0
TLS3_k127_4808451_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.417e-288 892.0
TLS3_k127_4808451_1 Actin K03569 - - 1.945e-203 638.0
TLS3_k127_4808451_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 583.0
TLS3_k127_4808451_3 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 552.0
TLS3_k127_4808451_4 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 483.0
TLS3_k127_4808451_5 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 415.0
TLS3_k127_4808451_6 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 304.0
TLS3_k127_4808451_7 RDD family - - - 0.000000000000000000000000000000000000000000000000000008623 194.0
TLS3_k127_4830465_0 Dehydratase family K01687 - 4.2.1.9 4.064e-313 965.0
TLS3_k127_4830465_1 Elongation factor G, domain IV K02355 - - 3.501e-196 634.0
TLS3_k127_4830465_10 - - - - 0.0000000000000000000000000009967 112.0
TLS3_k127_4830465_2 serine-type endopeptidase activity K04771 - 3.4.21.107 3.067e-194 615.0
TLS3_k127_4830465_3 PP-loop family K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 482.0
TLS3_k127_4830465_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 424.0
TLS3_k127_4830465_5 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 342.0
TLS3_k127_4830465_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005657 240.0
TLS3_k127_4830465_7 ATP-independent chaperone mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000009977 200.0
TLS3_k127_4830465_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000004754 147.0
TLS3_k127_4830465_9 domain protein K10716 - - 0.0000000000000000000000000000000000007985 148.0
TLS3_k127_4831857_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.633e-267 825.0
TLS3_k127_4831857_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 406.0
TLS3_k127_4831857_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 361.0
TLS3_k127_4831857_3 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000000000000001408 181.0
TLS3_k127_4831857_4 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000003535 140.0
TLS3_k127_4831857_5 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000001416 133.0
TLS3_k127_4831857_6 BolA family transcriptional regulator K09780 - - 0.0000000000000006694 80.0
TLS3_k127_4831857_7 repeat-containing protein - - - 0.00002521 57.0
TLS3_k127_4838590_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01153 - 3.1.21.3 0.0 1307.0
TLS3_k127_4838590_1 Macro domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 421.0
TLS3_k127_4838590_2 Domain of unknown function (DUF4433) - - - 0.000000000000000000000000000000000000000000002636 170.0
TLS3_k127_4840625_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 1.678e-286 891.0
TLS3_k127_4840625_1 rRNA (guanine-N2-)-methyltransferase activity K09846,K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.210,2.1.1.304,2.1.1.333 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 462.0
TLS3_k127_4840625_2 membrane K08976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 367.0
TLS3_k127_4840625_5 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000006179 217.0
TLS3_k127_4841695_0 bacterial (prokaryotic) histone like domain K04764 - - 0.000000000000000000001012 99.0
TLS3_k127_4841695_1 peptidyl-tyrosine sulfation K02450 - - 0.00000000000000002848 87.0
TLS3_k127_4865007_0 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 428.0
TLS3_k127_4865007_1 ATPase associated with various cellular activities, AAA_5 K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 327.0
TLS3_k127_4865007_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000001846 244.0
TLS3_k127_4865007_4 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000000000009549 184.0
TLS3_k127_4865007_5 Alginate export - - - 0.000000000000000000000006347 114.0
TLS3_k127_4885939_0 NADH-quinone oxidoreductase K00341,K05577 - 1.6.5.3 2.797e-231 728.0
TLS3_k127_4885939_1 NADH-quinone oxidoreductase K00341,K05577 - 1.6.5.3 5.024e-221 700.0
TLS3_k127_4885939_2 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000003423 198.0
TLS3_k127_4885939_3 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000003608 115.0
TLS3_k127_4885939_4 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.0000000000308 63.0
TLS3_k127_4887906_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.344e-275 863.0
TLS3_k127_4887906_1 amino acid - - - 8.063e-268 837.0
TLS3_k127_4887906_10 Evidence 2b Function of strongly homologous gene K18139 - - 0.00000000177 59.0
TLS3_k127_4887906_11 Fic/DOC family K07341 - - 0.000000003954 59.0
TLS3_k127_4887906_12 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.0002886 51.0
TLS3_k127_4887906_13 PFAM Ribbon-helix-helix protein, copG family K21495 - - 0.0008668 42.0
TLS3_k127_4887906_2 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 507.0
TLS3_k127_4887906_4 actin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 487.0
TLS3_k127_4887906_5 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 415.0
TLS3_k127_4887906_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 305.0
TLS3_k127_4887906_7 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001877 255.0
TLS3_k127_4887906_8 Evidence 2b Function of strongly homologous gene K02003,K09810,K09814 - - 0.000000000000000000000000000000000000000000000000000000005139 204.0
TLS3_k127_4887906_9 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000006684 145.0
TLS3_k127_4888669_0 NeuB family K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 412.0
TLS3_k127_4888669_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000339 271.0
TLS3_k127_4888669_2 Methyltransferase domain - - - 0.000000000000000000000002011 114.0
TLS3_k127_4888669_3 polysaccharide biosynthetic process - - - 0.00000009931 59.0
TLS3_k127_4903303_0 PFAM blue (type 1) copper domain protein - - - 0.00000002186 62.0
TLS3_k127_4903303_1 PFAM blue (type 1) copper domain protein - - - 0.0000008365 59.0
TLS3_k127_4905106_0 A circularly permuted ATPgrasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 603.0
TLS3_k127_4905106_1 dicarboxylic acid transport K03309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 580.0
TLS3_k127_4905106_11 - - - - 0.000000000000000000000648 102.0
TLS3_k127_4905106_13 Protein conserved in bacteria - - - 0.000000000000543 70.0
TLS3_k127_4905106_2 converts alpha-aldose to the beta-anomer K01785 GO:0003674,GO:0003824,GO:0004034,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006012,GO:0006082,GO:0006790,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1902776,GO:1902777 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 486.0
TLS3_k127_4905106_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 390.0
TLS3_k127_4905106_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 289.0
TLS3_k127_4905106_7 PFAM Bacterial domain of - - - 0.000000000000000000000000000000000000000000000001165 196.0
TLS3_k127_4905106_8 Bacterial transglutaminase-like N-terminal region - - - 0.0000000000000000000000000000000000000009214 168.0
TLS3_k127_4905106_9 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000004811 151.0
TLS3_k127_4915451_0 regulation of single-species biofilm formation K13572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 495.0
TLS3_k127_4915451_1 PIN domain K19686 - - 0.00000000000000000000000000000000000000000000000000000000001521 209.0
TLS3_k127_4915451_2 TupA-like ATPgrasp - - - 0.000000000000000000000000000000000000000005537 164.0
TLS3_k127_4915451_4 Cas6 Crispr - - - 0.000000000000000000000000000000000008 141.0
TLS3_k127_4915451_5 - - - - 0.000000000003714 67.0
TLS3_k127_4915451_6 TIGRFAM transcriptional regulator, AbrB family - - - 0.000000006512 61.0
TLS3_k127_4916035_0 TonB-dependent receptor K02014 - - 4e-323 1000.0
TLS3_k127_4916035_1 protein histidine kinase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 531.0
TLS3_k127_4916035_2 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 516.0
TLS3_k127_4916035_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000004577 239.0
TLS3_k127_4926182_0 AAA domain - - - 0.0 1228.0
TLS3_k127_4926182_1 regulation of translation K03704,K05809 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002495 256.0
TLS3_k127_4926182_2 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000003994 145.0
TLS3_k127_4926182_3 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000003315 61.0
TLS3_k127_4940501_1 response regulator - - - 0.00000000000000000000002478 106.0
TLS3_k127_4940501_2 Histidine kinase-like ATPases - - - 0.0000000000001258 79.0
TLS3_k127_4940501_3 DDE superfamily endonuclease - - - 0.0000001749 55.0
TLS3_k127_4940501_4 His Kinase A (phosphoacceptor) domain - - - 0.00001772 56.0
TLS3_k127_4940501_5 - - - - 0.0007936 44.0
TLS3_k127_4965630_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000005261 251.0
TLS3_k127_4965630_1 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000000002726 174.0
TLS3_k127_4967845_0 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 375.0
TLS3_k127_4967845_1 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000001318 228.0
TLS3_k127_4967845_3 phosphatase - - - 0.00000000000000000000000000000000000004249 146.0
TLS3_k127_4967845_6 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000009793 48.0
TLS3_k127_4967845_7 - - - - 0.0005702 50.0
TLS3_k127_4976382_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000006235 203.0
TLS3_k127_4976382_1 antisigma factor binding K03598 - - 0.000000000000000000000000000000000000000000003873 171.0
TLS3_k127_4976382_2 RNA recognition motif - - - 0.0000000000000000000000000003151 115.0
TLS3_k127_4976382_3 Protein of unknown function (DUF3309) - - - 0.000000000000000004361 85.0
TLS3_k127_5010190_0 PFAM alpha amylase, catalytic K05343 GO:0000023,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005975,GO:0005976,GO:0005977,GO:0005984,GO:0005991,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009311,GO:0009987,GO:0015980,GO:0016160,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0046872,GO:0047471,GO:0055114,GO:0071704 3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 396.0
TLS3_k127_5071797_0 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 361.0
TLS3_k127_5071797_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.000000000000000000000000000000000000000000000000000000000000000000000000000006378 266.0
TLS3_k127_5071797_2 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005927 231.0
TLS3_k127_5071797_3 - - - - 0.000000000000000000000000000000000000000000000001074 177.0
TLS3_k127_5071797_4 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000006521 115.0
TLS3_k127_5071797_5 Domain of unknown function (DUF4403) - - - 0.00000000000000000002809 105.0
TLS3_k127_5071797_6 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000002917 86.0
TLS3_k127_5098371_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 541.0
TLS3_k127_5098371_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0000000000000000007895 88.0
TLS3_k127_5098371_2 CsbD-like - - - 0.0000000000000002842 82.0
TLS3_k127_5103133_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03427 - 2.1.1.72 0.0 1343.0
TLS3_k127_5103133_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 462.0
TLS3_k127_5103133_2 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 363.0
TLS3_k127_5103133_3 ATPase involved in DNA repair K03546 - - 0.0000000000004585 70.0
TLS3_k127_5103133_4 - - - - 0.0000001956 54.0
TLS3_k127_5115808_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0 1042.0
TLS3_k127_5115808_1 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 527.0
TLS3_k127_5115808_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 408.0
TLS3_k127_5115808_3 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 401.0
TLS3_k127_5115808_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 300.0
TLS3_k127_5115808_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000628 162.0
TLS3_k127_5115808_6 self proteolysis - - - 0.000000000000000000000000000004874 131.0
TLS3_k127_5126975_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 515.0
TLS3_k127_5126975_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 308.0
TLS3_k127_5126975_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000105 226.0
TLS3_k127_5126975_3 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000145 167.0
TLS3_k127_5126975_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001677 106.0
TLS3_k127_5139966_0 belongs to the aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 1.167e-241 755.0
TLS3_k127_5139966_1 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 561.0
TLS3_k127_5139966_2 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 508.0
TLS3_k127_5139966_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 436.0
TLS3_k127_5139966_4 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 383.0
TLS3_k127_5139966_5 lactoylglutathione lyase activity K08234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 304.0
TLS3_k127_5139966_7 Domain of unknown function (DUF202) - - - 0.000000000001688 70.0
TLS3_k127_5168497_0 PFAM Radical SAM domain protein K22226 - - 0.0000000000000000000000003569 121.0
TLS3_k127_5168497_1 - - - - 0.000000000113 72.0
TLS3_k127_5168497_2 4Fe-4S single cluster domain K22227 - - 0.00000006249 63.0
TLS3_k127_5168497_3 Uncharacterised nucleotidyltransferase - - - 0.000001086 54.0
TLS3_k127_5170694_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 310.0
TLS3_k127_5170694_1 competence protein COMEC - - - 0.0000000000000000000029 99.0
TLS3_k127_5170694_2 HTH-like domain K07497 - - 0.00000000000000001009 89.0
TLS3_k127_51752_0 sodium:proton antiporter activity K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 430.0
TLS3_k127_51752_1 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007552 282.0
TLS3_k127_5177211_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.444e-281 871.0
TLS3_k127_5177211_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 7.646e-218 691.0
TLS3_k127_5177211_10 nucleotidyltransferase activity K17882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 344.0
TLS3_k127_5177211_11 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001878 244.0
TLS3_k127_5177211_13 belongs to the thioredoxin family K00384,K03671 - 1.8.1.9 0.00000000000000000000000000000000002427 139.0
TLS3_k127_5177211_14 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000005463 143.0
TLS3_k127_5177211_2 deoxyhypusine monooxygenase activity - - - 4.736e-195 625.0
TLS3_k127_5177211_3 ATP:ADP antiporter activity K03301 - - 5.401e-194 613.0
TLS3_k127_5177211_4 D-gluconate metabolic process K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 521.0
TLS3_k127_5177211_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 528.0
TLS3_k127_5177211_6 L-allo-threonine aldolase activity K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 473.0
TLS3_k127_5177211_7 protein-(glutamine-N5) methyltransferase activity K00543,K16130,K18896,K18897,K21515 - 2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 407.0
TLS3_k127_5177211_8 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 378.0
TLS3_k127_5177211_9 tRNA (guanine(37)-N(1))-methyltransferase activity K01091,K01633,K15429 - 1.13.11.81,2.1.1.228,3.1.3.18,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 355.0
TLS3_k127_5182017_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003082 258.0
TLS3_k127_5182017_1 anaphase-promoting complex-dependent catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000002874 206.0
TLS3_k127_5182017_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000001338 185.0
TLS3_k127_5182017_3 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.0000000000000000000000000000004073 123.0
TLS3_k127_5182017_4 Two component transcriptional regulator, winged helix family - - - 0.000000000000002927 80.0
TLS3_k127_5182017_5 Two component transcriptional regulator, winged helix family - - - 0.00003176 53.0
TLS3_k127_5182017_6 Helix-turn-helix XRE-family like proteins - - - 0.00004708 49.0
TLS3_k127_5194740_0 alcohol dehydrogenase K00060,K07777 - 1.1.1.103,2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 586.0
TLS3_k127_5194740_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 574.0
TLS3_k127_5194740_2 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002155 231.0
TLS3_k127_5194740_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000002725 81.0
TLS3_k127_5194740_4 energy transducer activity K03832 - - 0.0000000002806 71.0
TLS3_k127_5202201_0 B-1 B cell differentiation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 526.0
TLS3_k127_5202201_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009175 276.0
TLS3_k127_5202201_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000004266 70.0
TLS3_k127_5220611_0 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.00000000000000000000000000000000000000000000000001539 184.0
TLS3_k127_5220611_1 Signal Transduction Histidine Kinase - - - 0.00000000000000000000000000000000000000000000003348 190.0
TLS3_k127_5220611_2 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000001261 171.0
TLS3_k127_5220611_3 Shikimate kinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000001334 156.0
TLS3_k127_5220611_4 Ferritin, Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000001761 127.0
TLS3_k127_5220611_5 Protein of unknown function (DUF3175) - - - 0.00000000000000000000000009526 110.0
TLS3_k127_5249856_0 silver ion transport K15726 - - 3.4e-285 890.0
TLS3_k127_5249856_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 435.0
TLS3_k127_5249856_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 402.0
TLS3_k127_525253_0 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 389.0
TLS3_k127_525253_1 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000008546 109.0
TLS3_k127_525253_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000001219 100.0
TLS3_k127_5256974_0 Glycine-zipper domain - - - 0.0000000000000000000000000000000000002123 146.0
TLS3_k127_5256974_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000004903 123.0
TLS3_k127_5256974_3 Transposase IS116/IS110/IS902 family - GO:0003674,GO:0003824,GO:0004803,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0032196,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.000000000000000000005923 93.0
TLS3_k127_5256974_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000003779 92.0
TLS3_k127_5258777_0 Signal Transduction Histidine Kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 379.0
TLS3_k127_5258777_1 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000005147 250.0
TLS3_k127_5258777_2 PFAM response regulator receiveR - - - 0.00000000000000000000000000000000000000000000000000001195 192.0
TLS3_k127_5258777_3 Diguanylate cyclase - - - 0.000000000000000000000000000006732 136.0
TLS3_k127_5258777_4 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000008327 85.0
TLS3_k127_5258777_5 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000003043 86.0
TLS3_k127_5258777_7 Belongs to the peptidase M50B family - - - 0.00001841 53.0
TLS3_k127_5290321_0 MAPEG family - - - 0.000000000000000000000000000000000000000006704 158.0
TLS3_k127_5290321_1 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000002838 146.0
TLS3_k127_5290321_2 - - - - 0.00000000000000000008318 94.0
TLS3_k127_5290321_3 Domain of unknown function (DUF3806) - - - 0.000000000000001985 82.0
TLS3_k127_5290321_4 Domain of unknown function (DUF4440) - - - 0.0001618 50.0
TLS3_k127_52978_0 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000202 202.0
TLS3_k127_5307722_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.992e-206 656.0
TLS3_k127_5307722_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 381.0
TLS3_k127_5307722_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 349.0
TLS3_k127_5307722_3 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000005546 159.0
TLS3_k127_5307722_4 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000001715 145.0
TLS3_k127_5307722_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000001313 108.0
TLS3_k127_5307722_6 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000001621 109.0
TLS3_k127_5307722_7 - - - - 0.000000000006001 74.0
TLS3_k127_5307722_8 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000003214 61.0
TLS3_k127_5321171_0 isochorismatase, hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 293.0
TLS3_k127_5321171_1 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003144 241.0
TLS3_k127_5321171_2 FAD dependent oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000005979 173.0
TLS3_k127_5321171_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions - - - 0.00000000000000000000000000000001971 129.0
TLS3_k127_5321171_4 Protein of unknown function (DUF421) - - - 0.00000000004026 70.0
TLS3_k127_5323506_0 phosphate ion binding K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 458.0
TLS3_k127_5323506_1 Phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 388.0
TLS3_k127_5323506_2 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 368.0
TLS3_k127_5323506_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007877 267.0
TLS3_k127_5323506_4 - - - - 0.000000000000000000000000000000000000005596 153.0
TLS3_k127_5323506_8 - - - - 0.0000001627 61.0
TLS3_k127_5342633_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 6.135e-245 764.0
TLS3_k127_5342633_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 461.0
TLS3_k127_5342633_2 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 434.0
TLS3_k127_5342633_3 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 408.0
TLS3_k127_5342633_4 Cell cycle protein K03588 - - 0.000000000000000000000000000000009879 129.0
TLS3_k127_5342633_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000002591 56.0
TLS3_k127_5344774_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 437.0
TLS3_k127_5344774_2 PIN domain - - - 0.0000000000000000000000000000000000000000000166 166.0
TLS3_k127_5344774_3 positive regulation of growth - - - 0.0000000000000000000000005618 108.0
TLS3_k127_5344774_4 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000003445 96.0
TLS3_k127_5344774_5 PFAM SpoVT AbrB like domain K07172 - - 0.00001458 51.0
TLS3_k127_5344774_6 endonuclease - - - 0.0008399 49.0
TLS3_k127_5360062_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 530.0
TLS3_k127_5360062_1 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 401.0
TLS3_k127_5360062_2 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 383.0
TLS3_k127_5360062_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003659 261.0
TLS3_k127_5360062_5 Evidence 2b Function of strongly homologous gene K01740,K03430,K05306,K09469 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.00000000002665 64.0
TLS3_k127_5360062_7 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000003771 58.0
TLS3_k127_5360062_8 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000005596 56.0
TLS3_k127_5364404_0 Biotin carboxylase C-terminal domain K01959 - 6.4.1.1 1.716e-266 827.0
TLS3_k127_5364404_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 604.0
TLS3_k127_5364404_10 Regulatory protein, FmdB family - - - 0.0000000000000000000000174 103.0
TLS3_k127_5364404_12 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000003652 55.0
TLS3_k127_5364404_2 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 536.0
TLS3_k127_5364404_3 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K00973,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.24,2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 413.0
TLS3_k127_5364404_4 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 330.0
TLS3_k127_5364404_5 phosphate ion binding K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 307.0
TLS3_k127_5376173_0 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 384.0
TLS3_k127_5376173_1 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000005985 238.0
TLS3_k127_5376173_2 protein homooligomerization - - - 0.0000000000000000000000000000000000000000000000000001955 188.0
TLS3_k127_5376662_0 AAA domain K06919 - - 0.000000000000000000000000000000000000000000000000000002573 203.0
TLS3_k127_5376662_1 - - - - 0.00000000000000000000000000000000000000000000000000366 191.0
TLS3_k127_5376662_11 - - - - 0.000000000006715 72.0
TLS3_k127_5376662_15 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.00003408 53.0
TLS3_k127_5376662_2 Phage integrase family - - - 0.000000000000000000000000000000000000003576 161.0
TLS3_k127_5376662_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000001217 156.0
TLS3_k127_5376662_4 response regulator K02479,K07684,K07685 - - 0.00000000000000000000000000000000000009605 152.0
TLS3_k127_5376662_5 phosphorelay signal transduction system K02535 - 3.5.1.108 0.0000000000000000000000006916 108.0
TLS3_k127_5376662_6 DNA excision K02806 - - 0.000000000000000000003162 95.0
TLS3_k127_5376662_7 DNA primase - - - 0.0000000000000000003933 94.0
TLS3_k127_5376662_9 Protein of unknown function DUF72 - - - 0.00000000000000002122 86.0
TLS3_k127_5387489_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.678e-200 635.0
TLS3_k127_5387489_1 bacterial-type flagellum organization K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 368.0
TLS3_k127_5387489_2 oxidoreductase activity K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 345.0
TLS3_k127_5387489_3 rRNA binding K00185,K02967 - - 0.0000007656 60.0
TLS3_k127_5393255_0 Two component transcriptional regulator, LuxR family K07695 - - 0.00000000000000000000000000002317 127.0
TLS3_k127_5393255_1 Multicopper oxidase type - - - 0.000000000000000000000001774 109.0
TLS3_k127_5401532_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 1.519e-300 933.0
TLS3_k127_5401532_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 553.0
TLS3_k127_5401532_10 Membrane K08988 - - 0.00000000000000000002733 100.0
TLS3_k127_5401532_11 protein histidine kinase activity - - - 0.0000000001253 68.0
TLS3_k127_5401532_12 PFAM ATP-binding region, ATPase domain protein - - - 0.00000008585 54.0
TLS3_k127_5401532_13 diguanylate cyclase - - - 0.00000009034 57.0
TLS3_k127_5401532_2 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 336.0
TLS3_k127_5401532_3 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 319.0
TLS3_k127_5401532_4 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 312.0
TLS3_k127_5401532_5 Histidine kinase K02490 - - 0.000000000000000000000000000000000000000000000000001461 196.0
TLS3_k127_5401532_6 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000000000000002532 189.0
TLS3_k127_5401532_8 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000006078 145.0
TLS3_k127_5401932_2 response regulator K02282 - - 0.00000000000000000000000000000000000000000000000000000000006166 212.0
TLS3_k127_5401932_3 response regulator K02282 - - 0.00000000000000000000000000000000000000000000102 173.0
TLS3_k127_5401932_4 - - - - 0.000000000000000000000000000008989 131.0
TLS3_k127_5401932_5 Plasmid stabilization - - - 0.000000000000000000000000008788 112.0
TLS3_k127_5401932_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000002559 87.0
TLS3_k127_5401932_7 CBS domain - - - 0.00000000006934 64.0
TLS3_k127_5401932_8 PFAM CBS domain containing protein - - - 0.000000005765 64.0
TLS3_k127_5401932_9 BON domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.0000264 51.0
TLS3_k127_5405524_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01153 - 3.1.21.3 0.0 1818.0
TLS3_k127_5405524_1 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 485.0
TLS3_k127_5405524_2 Domain of unknown function (DUF4433) - - - 0.00000000000000000000000000000000000000000000000000000000000004003 217.0
TLS3_k127_5405524_3 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000002915 198.0
TLS3_k127_5405524_4 sequence-specific DNA binding K18830 - - 0.000000000000000000418 90.0
TLS3_k127_5412984_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 429.0
TLS3_k127_5412984_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 288.0
TLS3_k127_5412984_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000001044 85.0
TLS3_k127_5422220_0 Bacterial extracellular solute-binding protein K02027,K10117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 514.0
TLS3_k127_5422220_1 helix_turn _helix lactose operon repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002118 268.0
TLS3_k127_5422220_2 ABC transporter (Permease) K10118 - - 0.00000000006455 65.0
TLS3_k127_5432413_0 molybdopterin cofactor binding K00370,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4 0.0 1195.0
TLS3_k127_5432413_1 response regulator K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004396 258.0
TLS3_k127_5432413_2 Histidine kinase K07683 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005823 256.0
TLS3_k127_5435556_0 PFAM Citrate transporter - - - 1.926e-202 640.0
TLS3_k127_5447943_0 GAF domain - - - 1.387e-300 935.0
TLS3_k127_5447943_1 Bacterial regulatory protein, Fis family K07714 - - 5.805e-220 690.0
TLS3_k127_5447943_2 sulfate reduction K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 411.0
TLS3_k127_5447943_3 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 287.0
TLS3_k127_5447943_4 Integrase core domain - - - 0.00000000000000000000000000000000258 131.0
TLS3_k127_5447943_5 Transposase and inactivated derivatives - - - 0.0000000000001618 79.0
TLS3_k127_5447943_6 Transposase - - - 0.0000002493 52.0
TLS3_k127_5457449_0 GHKL domain K13598 - 2.7.13.3 9.405e-290 899.0
TLS3_k127_5457449_1 Domain of unknown function (DUF1844) - - - 0.00000000000000000002644 90.0
TLS3_k127_5460707_0 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 494.0
TLS3_k127_5460707_1 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 455.0
TLS3_k127_5460707_2 heat shock protein binding K05516,K05801,K18481 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001474 267.0
TLS3_k127_5460707_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000005898 180.0
TLS3_k127_5460707_5 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000003951 166.0
TLS3_k127_551130_0 radical SAM domain protein - - - 0.0 1022.0
TLS3_k127_551130_1 NHL repeat - - - 5.225e-239 742.0
TLS3_k127_551130_10 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 465.0
TLS3_k127_551130_11 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 457.0
TLS3_k127_551130_13 4 iron, 4 sulfur cluster binding K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007971 273.0
TLS3_k127_551130_15 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000001457 179.0
TLS3_k127_551130_16 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000004677 158.0
TLS3_k127_551130_18 Putative addiction module component - - - 0.000000000000000000000000000000002747 130.0
TLS3_k127_551130_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000001682 101.0
TLS3_k127_551130_2 - - - - 3.385e-206 642.0
TLS3_k127_551130_20 - - - - 0.000000000000004266 77.0
TLS3_k127_551130_21 Plasmid stabilization system K19092 - - 0.0000000001826 66.0
TLS3_k127_551130_3 denitrification pathway - - - 3.232e-199 630.0
TLS3_k127_551130_4 denitrification pathway - - - 5.005e-196 619.0
TLS3_k127_551130_5 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 601.0
TLS3_k127_551130_6 anaphase-promoting complex binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 595.0
TLS3_k127_551130_7 protein complex oligomerization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 515.0
TLS3_k127_551130_8 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 516.0
TLS3_k127_551130_9 Type I site-specific restriction-modification system, R (Restriction) subunit and related K01156 - 3.1.21.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 496.0
TLS3_k127_552179_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0 1111.0
TLS3_k127_552179_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.084e-276 859.0
TLS3_k127_552179_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 9.929e-204 636.0
TLS3_k127_552179_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 498.0
TLS3_k127_552179_4 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 394.0
TLS3_k127_552179_5 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 342.0
TLS3_k127_552179_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 331.0
TLS3_k127_552179_7 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 298.0
TLS3_k127_552179_8 RNA-DNA hybrid ribonuclease activity K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000003493 187.0
TLS3_k127_552179_9 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000009076 143.0
TLS3_k127_5533165_0 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 307.0
TLS3_k127_5533165_1 Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002385 280.0
TLS3_k127_5533165_2 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007537 271.0
TLS3_k127_5533165_3 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000002488 211.0
TLS3_k127_5533165_4 integrase family - - - 0.000000000000000000000000000000000001044 142.0
TLS3_k127_5533165_5 - - - - 0.0000000000000000000000000000001022 128.0
TLS3_k127_5533165_6 Winged helix-turn helix - - - 0.00000000000000000000000272 106.0
TLS3_k127_5538515_0 proline dipeptidase activity K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 570.0
TLS3_k127_5538515_1 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 352.0
TLS3_k127_5538515_3 protein secretion K03116 - - 0.00000000000000000000001385 103.0
TLS3_k127_5544409_0 methylisocitrate lyase activity K01841,K07281 - 2.7.7.74,5.4.2.9 1.488e-303 935.0
TLS3_k127_5544409_1 Iron permease FTR1 family K07243 - - 1.218e-287 897.0
TLS3_k127_5544409_10 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 317.0
TLS3_k127_5544409_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 308.0
TLS3_k127_5544409_12 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000181 253.0
TLS3_k127_5544409_13 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000004725 235.0
TLS3_k127_5544409_14 phosphate starvation-inducible protein, PsiF - - - 0.0000000000000000000004941 98.0
TLS3_k127_5544409_15 YacP-like NYN domain K06962 - - 0.0000000000000000000014 102.0
TLS3_k127_5544409_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 8.209e-243 758.0
TLS3_k127_5544409_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 2.513e-226 708.0
TLS3_k127_5544409_4 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 557.0
TLS3_k127_5544409_5 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 416.0
TLS3_k127_5544409_6 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 379.0
TLS3_k127_5544409_7 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 376.0
TLS3_k127_5544409_8 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 361.0
TLS3_k127_5544409_9 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 368.0
TLS3_k127_5602126_1 Protein of unknown function (DUF2914) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 480.0
TLS3_k127_5602126_2 Glycosyltransferase family 28 N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 384.0
TLS3_k127_5602126_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001912 235.0
TLS3_k127_5602126_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000001667 181.0
TLS3_k127_5620945_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007203 262.0
TLS3_k127_5620945_2 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000007682 199.0
TLS3_k127_5620945_4 domain, Protein K18491 - - 0.00000000000000009479 88.0
TLS3_k127_5630902_0 NADH dehydrogenase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 452.0
TLS3_k127_5630902_1 - - - - 0.0000000000000000000000000000005555 129.0
TLS3_k127_5630902_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000001422 123.0
TLS3_k127_5636992_0 Domain of unknown function (DUF1929) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001744 235.0
TLS3_k127_5636992_1 Protein of unknown function (DUF2442) - - - 0.00000000000000000009002 101.0
TLS3_k127_5636992_2 nuclease - - - 0.00000000000000006098 83.0
TLS3_k127_5656262_0 Chalcone and stilbene synthases, C-terminal domain K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 309.0
TLS3_k127_5656262_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009322 241.0
TLS3_k127_5656262_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000005674 113.0
TLS3_k127_5721043_0 Belongs to the DegT DnrJ EryC1 family K20429 - 2.6.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 332.0
TLS3_k127_5721043_1 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 318.0
TLS3_k127_5721043_2 Transcription termination factor nusG - - - 0.0000000000000000000000000000000000000000002788 164.0
TLS3_k127_5721043_3 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000000000000004989 140.0
TLS3_k127_5721043_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000006412 74.0
TLS3_k127_5722625_0 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 451.0
TLS3_k127_5722625_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 433.0
TLS3_k127_5722625_2 pseudouridine synthase activity K06176 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 417.0
TLS3_k127_5722625_3 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 366.0
TLS3_k127_5722625_4 tRNA 3'-trailer cleavage - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 364.0
TLS3_k127_5722625_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 317.0
TLS3_k127_5722625_6 deoxyhypusine monooxygenase activity K02632 - 4.4.1.31 0.0000000000000000000000000000000000000000000000000000000000000000001832 235.0
TLS3_k127_5730930_0 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 418.0
TLS3_k127_5730930_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000008027 199.0
TLS3_k127_5730930_2 Regulatory protein, FmdB family - - - 0.0000000000000000000000000006682 120.0
TLS3_k127_5737767_0 Glycosyl hydrolases family 15 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 458.0
TLS3_k127_5737767_1 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000007161 246.0
TLS3_k127_5737767_2 GHKL domain - - - 0.000000000000000000000000000000000000000000000000000002899 218.0
TLS3_k127_5776673_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 5.954e-312 965.0
TLS3_k127_5776673_1 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 536.0
TLS3_k127_5776673_2 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 487.0
TLS3_k127_5776673_3 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 441.0
TLS3_k127_5776673_4 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 312.0
TLS3_k127_5776673_5 photosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 298.0
TLS3_k127_5776673_6 GGDEF domain - - - 0.00000000000000000000000000000000000000000000003937 172.0
TLS3_k127_5776673_7 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000002755 170.0
TLS3_k127_5779355_0 Surface antigen K07277 - - 1.474e-283 882.0
TLS3_k127_5779355_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 481.0
TLS3_k127_5789395_0 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001719 264.0
TLS3_k127_5789395_1 L-lysine 6-monooxygenase (NADPH-requiring) K03897 - 1.14.13.59 0.000000000000000000000000000000000000000000000005456 188.0
TLS3_k127_5789395_2 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000002231 130.0
TLS3_k127_5789395_3 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000008846 128.0
TLS3_k127_5789395_4 Sugar efflux transporter for intercellular exchange K15383 - - 0.000000000000000001419 88.0
TLS3_k127_5806974_0 belongs to the aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 0.0 1222.0
TLS3_k127_5806974_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 1.463e-252 788.0
TLS3_k127_5806974_2 Protein involved in outer membrane biogenesis K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 535.0
TLS3_k127_5806974_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 486.0
TLS3_k127_5806974_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 434.0
TLS3_k127_5806974_5 methyltransferase K16129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 361.0
TLS3_k127_5806974_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000000000000000652 158.0
TLS3_k127_5806974_9 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000005291 85.0
TLS3_k127_582373_0 Surface antigen variable number K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 470.0
TLS3_k127_582373_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000008866 174.0
TLS3_k127_582373_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000004263 140.0
TLS3_k127_5877551_0 siderophore transport K02014 - - 0.0 1244.0
TLS3_k127_5877551_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 554.0
TLS3_k127_5877551_2 transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000003075 214.0
TLS3_k127_5877551_3 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000672 138.0
TLS3_k127_5877551_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000005837 130.0
TLS3_k127_5877551_5 Anaphase-promoting complex subunit 4 WD40 domain - - - 0.0000000000000000000000001831 114.0
TLS3_k127_5877551_6 cobalamin synthesis protein P47K - - - 0.0000000000000000000002746 109.0
TLS3_k127_5877551_8 chaperone-mediated protein complex assembly - - - 0.00000000000000001838 85.0
TLS3_k127_5877551_9 Alternative locus ID - - - 0.00000000000008845 77.0
TLS3_k127_5903322_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 441.0
TLS3_k127_5903322_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 383.0
TLS3_k127_5903322_2 Type II secretory pathway component ExeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000002337 239.0
TLS3_k127_5903322_4 PFAM metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.000000000000149 76.0
TLS3_k127_5904132_0 ABC transporter K06020 - 3.6.3.25 0.0 1051.0
TLS3_k127_5904132_1 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 354.0
TLS3_k127_5904132_2 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 304.0
TLS3_k127_5904132_4 coenzyme F420 binding K07226 - - 0.000000001774 59.0
TLS3_k127_5904132_6 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00001771 48.0
TLS3_k127_5919502_0 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 497.0
TLS3_k127_5919502_1 Ammonium transporter K03320,K06580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 443.0
TLS3_k127_5921781_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 468.0
TLS3_k127_5921781_1 DNA-binding transcription factor activity K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 463.0
TLS3_k127_5921781_10 transposase and inactivated derivatives, IS30 family - - - 0.00000000000000000000000000000002614 130.0
TLS3_k127_5921781_11 - - - - 0.000004196 52.0
TLS3_k127_5921781_2 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 429.0
TLS3_k127_5921781_3 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 389.0
TLS3_k127_5921781_4 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 342.0
TLS3_k127_5921781_5 Ferritin-like domain K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002941 250.0
TLS3_k127_5921781_6 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000001762 230.0
TLS3_k127_5921781_7 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000001276 188.0
TLS3_k127_5921781_8 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000003144 175.0
TLS3_k127_5936192_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1011.0
TLS3_k127_5936192_1 B3/4 domain K01890 - 6.1.1.20 7.523e-249 779.0
TLS3_k127_5936192_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 8.656e-249 779.0
TLS3_k127_5936192_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 326.0
TLS3_k127_5936192_4 Translation initiation factor IF-3, C-terminal domain K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 291.0
TLS3_k127_5936192_5 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000775 210.0
TLS3_k127_5936192_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002111 193.0
TLS3_k127_5936192_7 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000005136 159.0
TLS3_k127_5936192_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000001632 149.0
TLS3_k127_5936192_9 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000002467 70.0
TLS3_k127_5950507_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 434.0
TLS3_k127_5950507_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 399.0
TLS3_k127_5950507_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 394.0
TLS3_k127_5950507_3 peroxidase activity K09162 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114 1.13.11.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 293.0
TLS3_k127_5950507_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.00000000000000000000000000000000002638 135.0
TLS3_k127_5959243_0 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 432.0
TLS3_k127_5959243_1 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000008203 247.0
TLS3_k127_5959243_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000005978 242.0
TLS3_k127_5959243_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000004163 207.0
TLS3_k127_5959243_4 negative regulation of translational initiation K05554,K14670,K15886 - 2.3.1.235 0.0000000000000000000000000000000000000000000000002735 182.0
TLS3_k127_5959243_6 DNA-sulfur modification-associated - - - 0.0000002283 63.0
TLS3_k127_5961722_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.941e-256 803.0
TLS3_k127_5961722_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000001198 196.0
TLS3_k127_5961722_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000001658 192.0
TLS3_k127_5961722_3 Anti-sigma-K factor rskA K18682 - - 0.00000000000000000000000000000000000000000003066 169.0
TLS3_k127_5961722_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000002346 76.0
TLS3_k127_598561_0 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 5.111e-196 618.0
TLS3_k127_598561_1 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 514.0
TLS3_k127_598561_2 Outer membrane protease K01355,K08477,K08566,K13520 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009279,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0043170,GO:0044238,GO:0044425,GO:0044462,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.23.48,3.4.23.49 0.000000000000000000000000000000000000000000000000000000000000008084 228.0
TLS3_k127_6006212_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.692e-262 812.0
TLS3_k127_6006212_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.308e-235 735.0
TLS3_k127_6006212_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 433.0
TLS3_k127_6006212_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 289.0
TLS3_k127_6006212_4 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000004539 238.0
TLS3_k127_6006212_5 PFAM O-methyltransferase family 2 - - - 0.0000000000000000000000000000000000000000000002065 181.0
TLS3_k127_6021931_0 Glycogen debranching enzyme - - - 6.387e-278 870.0
TLS3_k127_6021931_1 lipopolysaccharide transport K22110 - - 1.161e-239 743.0
TLS3_k127_6021931_2 - K11477 - - 0.000000000000000000000000000000000000000000000000000000000000000006054 230.0
TLS3_k127_6021931_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000002382 111.0
TLS3_k127_6029450_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000004893 246.0
TLS3_k127_6029450_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000003843 70.0
TLS3_k127_6036161_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 2022.0
TLS3_k127_6036161_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 8.325e-248 772.0
TLS3_k127_6036161_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001551 259.0
TLS3_k127_6036161_11 GDP-mannose mannosyl hydrolase activity K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001988 256.0
TLS3_k127_6036161_12 ACT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002626 222.0
TLS3_k127_6036161_14 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000001958 188.0
TLS3_k127_6036161_16 LysM domain - - - 0.00000000000000000000000000000000000000007051 158.0
TLS3_k127_6036161_19 nuclease activity K06218 - - 0.00000000000000000000000000000000664 128.0
TLS3_k127_6036161_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 612.0
TLS3_k127_6036161_3 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 590.0
TLS3_k127_6036161_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 588.0
TLS3_k127_6036161_5 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 529.0
TLS3_k127_6036161_6 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 462.0
TLS3_k127_6036161_7 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 411.0
TLS3_k127_6036161_8 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 374.0
TLS3_k127_6036161_9 23S rRNA (guanine(2445)-N(2))-methyltransferase activity K07444,K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 357.0
TLS3_k127_6042650_0 Probable molybdopterin binding domain K03750 - 2.10.1.1 1.363e-228 713.0
TLS3_k127_6042650_1 Trypsin K04771 - 3.4.21.107 5.757e-226 709.0
TLS3_k127_6042650_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 602.0
TLS3_k127_6042650_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 451.0
TLS3_k127_6042650_4 Mo-molybdopterin cofactor metabolic process K03750,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.000000000000000000000000000000000000222 141.0
TLS3_k127_6043259_0 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003251 293.0
TLS3_k127_6043259_1 Peptidase C39 family K06992 - - 0.000000000000000000000000000000000000000000000000000000000000000009718 231.0
TLS3_k127_6043259_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000002356 98.0
TLS3_k127_6043259_3 - - - - 0.00000000000000007232 87.0
TLS3_k127_6043259_4 - - - - 0.00000000000001387 79.0
TLS3_k127_6043259_5 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.00000000008721 70.0
TLS3_k127_6043259_6 PhoQ Sensor - - - 0.000000002994 59.0
TLS3_k127_6043259_7 - - - - 0.000001471 58.0
TLS3_k127_6046218_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.195e-296 920.0
TLS3_k127_6046218_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 584.0
TLS3_k127_6046218_10 bacterial-type flagellum organization K02398 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009892,GO:0010556,GO:0010605,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031324,GO:0031326,GO:0032268,GO:0032269,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000000000000000000002996 99.0
TLS3_k127_6046218_11 Flagellar rod assembly protein muramidase FlgJ K02395,K08309 - - 0.0000000000000003628 83.0
TLS3_k127_6046218_12 COG1344 Flagellin and related hook-associated proteins K02397 - - 0.0000000003617 65.0
TLS3_k127_6046218_2 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 489.0
TLS3_k127_6046218_3 Sigma-70, region 4 K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 358.0
TLS3_k127_6046218_4 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 334.0
TLS3_k127_6046218_5 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 329.0
TLS3_k127_6046218_6 Cellulose biosynthesis protein BcsQ K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 327.0
TLS3_k127_6046218_7 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 317.0
TLS3_k127_6046218_8 SRP54-type protein, GTPase domain K02404 - - 0.00000000000000000000000000000000000000000000000000002992 204.0
TLS3_k127_6046218_9 bacterial-type flagellum organization K02279,K02386 - - 0.0000000000000000000000000000000000000000000001748 177.0
TLS3_k127_6053150_0 Formate--tetrahydrofolate ligase K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 3.167e-266 829.0
TLS3_k127_6053150_1 succinyl-diaminopimelate desuccinylase activity - - - 3.971e-241 751.0
TLS3_k127_6053150_10 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000004041 105.0
TLS3_k127_6053150_11 Predicted membrane protein (DUF2207) - - - 0.00000000000002078 80.0
TLS3_k127_6053150_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 577.0
TLS3_k127_6053150_3 stress-induced mitochondrial fusion K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 534.0
TLS3_k127_6053150_4 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 499.0
TLS3_k127_6053150_5 stress-induced mitochondrial fusion K04087 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 466.0
TLS3_k127_6053150_6 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 426.0
TLS3_k127_6053150_7 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 338.0
TLS3_k127_6053150_8 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000003753 239.0
TLS3_k127_6055988_0 cobalamin-transporting ATPase activity K02014,K16092 - - 2.512e-220 702.0
TLS3_k127_6055988_1 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 350.0
TLS3_k127_6055988_2 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 297.0
TLS3_k127_6076549_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1224.0
TLS3_k127_6076549_1 - - - - 0.000000000000000000000000000000000000000000000000000004438 193.0
TLS3_k127_6101554_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 334.0
TLS3_k127_6101554_1 tungstate binding K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 300.0
TLS3_k127_6107376_0 Flagellar motor switch protein FliM K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 468.0
TLS3_k127_6107376_1 Flagellar basal body protein FlaE K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 375.0
TLS3_k127_6107376_2 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 349.0
TLS3_k127_6107376_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 351.0
TLS3_k127_6107376_4 Role in flagellar biosynthesis K02421 - - 0.00000000000000000000000000000000000007583 152.0
TLS3_k127_6107376_5 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000000000000000000002828 141.0
TLS3_k127_6107376_6 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000000003089 141.0
TLS3_k127_6107376_7 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000001262 135.0
TLS3_k127_6107376_8 Role in flagellar biosynthesis K02420 - - 0.000000000000000000000000009484 114.0
TLS3_k127_6107376_9 flagellar K02418,K02419 - - 0.0000000000004377 75.0
TLS3_k127_6143952_0 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 562.0
TLS3_k127_6143952_1 Short-chain dehydrogenase reductase sdr K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000007893 211.0
TLS3_k127_6143952_2 gntR family K05799 - - 0.000185 46.0
TLS3_k127_6143952_3 PFAM Cupin 2, conserved barrel K14673 - - 0.0003 49.0
TLS3_k127_6145673_0 metallopeptidase activity K03568 - - 1.387e-258 803.0
TLS3_k127_6145673_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 577.0
TLS3_k127_6145673_2 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 555.0
TLS3_k127_6145673_3 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000914 280.0
TLS3_k127_6145673_4 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000003065 221.0
TLS3_k127_6145673_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K10907 - - 0.000000000002031 69.0
TLS3_k127_6145673_7 Protein with unknown function (DUF469) K09923 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00002557 46.0
TLS3_k127_6154947_0 Type II/IV secretion system protein K02454,K02652 - - 4.711e-296 916.0
TLS3_k127_6154947_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 527.0
TLS3_k127_6154947_2 Pilus assembly protein K02662 - - 0.0000000000003078 74.0
TLS3_k127_6154947_3 Putative peptidoglycan binding domain - - - 0.00000001231 59.0
TLS3_k127_6201130_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 345.0
TLS3_k127_6201130_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 284.0
TLS3_k127_6201130_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000006556 162.0
TLS3_k127_6217492_0 NeuB family K03856 - 2.5.1.54 2.385e-200 626.0
TLS3_k127_6217492_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 597.0
TLS3_k127_6217492_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 519.0
TLS3_k127_6217492_3 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 451.0
TLS3_k127_6217492_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004017 278.0
TLS3_k127_6217492_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000396 182.0
TLS3_k127_6218270_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 2130.0
TLS3_k127_6237049_0 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000001165 202.0
TLS3_k127_6237049_1 Belongs to the 'phage' integrase family - - - 0.00000000000261 68.0
TLS3_k127_6254363_0 guanyl-nucleotide exchange factor activity - - - 3.585e-210 668.0
TLS3_k127_6254363_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 427.0
TLS3_k127_6254363_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 369.0
TLS3_k127_6254363_3 phosphopentomutase activity K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 365.0
TLS3_k127_6254363_4 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 362.0
TLS3_k127_6254363_5 deoxyribose-phosphate aldolase activity K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 345.0
TLS3_k127_6254363_6 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000003743 222.0
TLS3_k127_6254363_7 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000003018 209.0
TLS3_k127_6254363_8 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000001732 174.0
TLS3_k127_6254363_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000002098 97.0
TLS3_k127_6256312_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 1.021e-233 736.0
TLS3_k127_6256312_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 3.176e-198 630.0
TLS3_k127_6256312_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 2.273e-197 618.0
TLS3_k127_6256312_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 590.0
TLS3_k127_6256312_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 577.0
TLS3_k127_6256312_5 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 370.0
TLS3_k127_6256312_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 323.0
TLS3_k127_6256312_7 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000002184 104.0
TLS3_k127_6256359_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.781e-242 754.0
TLS3_k127_6256359_1 Competence protein K02238 - - 1.617e-195 638.0
TLS3_k127_6256359_2 NUBPL iron-transfer P-loop NTPase K16554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 466.0
TLS3_k127_6256359_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 297.0
TLS3_k127_6256359_4 O-Antigen ligase K02847,K13009 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 302.0
TLS3_k127_6256359_5 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000084 213.0
TLS3_k127_6256359_6 export protein K01991 - - 0.0000000006228 70.0
TLS3_k127_6258765_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 559.0
TLS3_k127_6258765_1 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000006658 220.0
TLS3_k127_6258765_2 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000001042 111.0
TLS3_k127_6258765_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000002341 113.0
TLS3_k127_6258765_4 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000004445 106.0
TLS3_k127_6258765_5 GAF domain K20962 - 3.1.4.52 0.0000000000000007017 92.0
TLS3_k127_6258765_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.00000005622 55.0
TLS3_k127_6258765_8 - - - - 0.00000006473 55.0
TLS3_k127_6258765_9 - - - - 0.00000294 51.0
TLS3_k127_6269598_0 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 387.0
TLS3_k127_6269598_1 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001404 273.0
TLS3_k127_6269598_2 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000001384 177.0
TLS3_k127_6269598_3 - - - - 0.00002136 52.0
TLS3_k127_6272368_0 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 328.0
TLS3_k127_6272368_1 Hpt domain - - - 0.00000000000000000000000000000000000000000006676 176.0
TLS3_k127_6272368_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000002042 126.0
TLS3_k127_6275709_0 PFAM Cna B domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 431.0
TLS3_k127_6312415_0 Beta-Casp domain K07576 - - 3.671e-238 744.0
TLS3_k127_6312415_1 aminopeptidase activity K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 568.0
TLS3_k127_6312415_10 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000215 191.0
TLS3_k127_6312415_13 RF-1 domain K15034 - - 0.00000000000000000000000000000000000000000000000005463 181.0
TLS3_k127_6312415_15 acetyltransferase - - - 0.000000000000000000000000000000000000000000004611 168.0
TLS3_k127_6312415_16 Protein of unknown function (DUF2490) - - - 0.000000000000000000000000000000001299 140.0
TLS3_k127_6312415_18 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000000006958 118.0
TLS3_k127_6312415_19 carbonate dehydratase activity K01674 - 4.2.1.1 0.000000000000006509 76.0
TLS3_k127_6312415_2 FIST C domain - GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 465.0
TLS3_k127_6312415_20 - - - - 0.00000000000004822 76.0
TLS3_k127_6312415_3 Aminomethyltransferase folate-binding domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 441.0
TLS3_k127_6312415_4 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 409.0
TLS3_k127_6312415_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 405.0
TLS3_k127_6312415_6 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001857 276.0
TLS3_k127_6312415_7 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000001526 226.0
TLS3_k127_6312415_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000001188 222.0
TLS3_k127_6313964_0 Type II/IV secretion system protein K02454,K02652 - - 0.0 1246.0
TLS3_k127_6313964_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.09e-262 818.0
TLS3_k127_6313964_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 571.0
TLS3_k127_6313964_5 RNA-binding protein - - - 0.0000000002618 64.0
TLS3_k127_6313964_6 peptidase - - - 0.000000007617 62.0
TLS3_k127_6331124_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1118.0
TLS3_k127_6331124_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 1.327e-320 992.0
TLS3_k127_6331124_10 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 395.0
TLS3_k127_6331124_11 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 387.0
TLS3_k127_6331124_12 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 372.0
TLS3_k127_6331124_13 Cytochrome c K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 304.0
TLS3_k127_6331124_14 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 290.0
TLS3_k127_6331124_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005669 272.0
TLS3_k127_6331124_17 Cytochrome c K17052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004663 266.0
TLS3_k127_6331124_18 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000005197 254.0
TLS3_k127_6331124_19 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000199 235.0
TLS3_k127_6331124_2 aerobic electron transport chain K00425,K08738 - 1.10.3.14 1.93e-254 795.0
TLS3_k127_6331124_20 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000004032 233.0
TLS3_k127_6331124_22 adenosylhomocysteine nucleosidase activity K01243,K03527 - 1.17.7.4,3.2.2.9 0.00000000000000000000000000000000000000000005938 170.0
TLS3_k127_6331124_23 - - - - 0.00000000000000000000000000000000000001373 148.0
TLS3_k127_6331124_24 phosphatidylinositol metabolic process K00728 - 2.4.1.109 0.000000000000000000000000000000000007349 152.0
TLS3_k127_6331124_25 Evidence 5 No homology to any previously reported sequences K07126 - - 0.000000000000000000000000000000008059 139.0
TLS3_k127_6331124_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 1.89e-215 673.0
TLS3_k127_6331124_4 Cytochrome b/b6/petB K00412 - - 5.61e-206 645.0
TLS3_k127_6331124_5 Domain of unknown function (DUF3463) - - - 1.637e-203 635.0
TLS3_k127_6331124_6 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 553.0
TLS3_k127_6331124_7 oxidoreductase activity, acting on diphenols and related substances as donors K00240,K03886 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 488.0
TLS3_k127_6331124_8 Cytochrome c K02305,K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 431.0
TLS3_k127_6331124_9 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 413.0
TLS3_k127_6336288_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 372.0
TLS3_k127_6336288_1 denitrification pathway K02569,K03532,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 355.0
TLS3_k127_6336288_2 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 308.0
TLS3_k127_6336288_3 Mo-molybdopterin cofactor metabolic process K03750,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000001398 265.0
TLS3_k127_6336288_4 macromolecule localization K01421,K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000004062 213.0
TLS3_k127_6352216_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity - - - 8.724e-229 714.0
TLS3_k127_6352216_1 cobalamin binding K21089,K21972,K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 316.0
TLS3_k127_6352216_2 PFAM NapC NirT cytochrome c K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001714 268.0
TLS3_k127_6352216_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000001229 250.0
TLS3_k127_6352216_4 Cytochrome c - - - 0.0000000000000000000000000000000004663 145.0
TLS3_k127_6352216_5 Protein conserved in bacteria - - - 0.000000000000000000000000000004381 121.0
TLS3_k127_6352216_7 Small metal-binding protein - - - 0.000000000001691 73.0
TLS3_k127_6352216_8 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.000009263 48.0
TLS3_k127_6382359_0 lipopolysaccharide transport K22110 - - 2.924e-256 796.0
TLS3_k127_6382359_1 pectinesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 426.0
TLS3_k127_6382359_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004826 271.0
TLS3_k127_6382359_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003139 267.0
TLS3_k127_6388506_0 Molydopterin dinucleotide binding domain K00302,K10814 - 1.4.99.5,1.5.3.1 0.0 1414.0
TLS3_k127_6388506_1 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 0.0 1030.0
TLS3_k127_6388506_10 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 567.0
TLS3_k127_6388506_11 CHASE3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 550.0
TLS3_k127_6388506_12 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 537.0
TLS3_k127_6388506_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 544.0
TLS3_k127_6388506_14 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 506.0
TLS3_k127_6388506_15 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 452.0
TLS3_k127_6388506_16 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 407.0
TLS3_k127_6388506_17 coenzyme binding K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 396.0
TLS3_k127_6388506_18 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 409.0
TLS3_k127_6388506_19 Flagellar Motor Protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 396.0
TLS3_k127_6388506_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342,K05575 - 1.6.5.3 5.76e-298 921.0
TLS3_k127_6388506_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 351.0
TLS3_k127_6388506_21 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 353.0
TLS3_k127_6388506_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 331.0
TLS3_k127_6388506_23 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 298.0
TLS3_k127_6388506_24 sirohydrochlorin cobaltochelatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 291.0
TLS3_k127_6388506_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 282.0
TLS3_k127_6388506_26 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 285.0
TLS3_k127_6388506_27 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005974 259.0
TLS3_k127_6388506_28 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000535 256.0
TLS3_k127_6388506_29 Outer Membrane Lipoprotein K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007249 250.0
TLS3_k127_6388506_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 1.354e-263 812.0
TLS3_k127_6388506_30 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002791 244.0
TLS3_k127_6388506_31 NADH dehydrogenase (ubiquinone) activity K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000149 222.0
TLS3_k127_6388506_32 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000000000000000000000000002248 188.0
TLS3_k127_6388506_33 - - - - 0.00000000000000000000000000000000000000000000000002784 184.0
TLS3_k127_6388506_34 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000001265 166.0
TLS3_k127_6388506_36 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000003216 139.0
TLS3_k127_6388506_37 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000001754 142.0
TLS3_k127_6388506_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 1.62e-256 799.0
TLS3_k127_6388506_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.868e-250 780.0
TLS3_k127_6388506_6 Belongs to the DNA photolyase family K01669 - 4.1.99.3 7.408e-229 718.0
TLS3_k127_6388506_7 Flavin containing amine oxidoreductase K06954 - - 3.36e-199 627.0
TLS3_k127_6388506_8 PFAM NAD-dependent epimerase dehydratase - - - 3.488e-195 622.0
TLS3_k127_6388506_9 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 570.0
TLS3_k127_6411424_0 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 412.0
TLS3_k127_6411424_1 RNA polymerase, sigma-24 subunit, ECF subfamily - - - 0.00000000000000000000000000000000000003275 151.0
TLS3_k127_6411424_2 Involved in the tonB-independent uptake of proteins K01771 - 4.6.1.13 0.000000000000000000000000000000008424 142.0
TLS3_k127_6411424_3 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000465 121.0
TLS3_k127_6411424_4 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.0000000000000000000000002917 109.0
TLS3_k127_6413655_0 cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 518.0
TLS3_k127_6413655_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 301.0
TLS3_k127_6413655_2 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 293.0
TLS3_k127_6413655_3 Dihaem cytochrome c - - - 0.0000000000000000000000000000000000003516 145.0
TLS3_k127_6413655_4 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000001702 136.0
TLS3_k127_6413655_5 required for the transposition of insertion element IS2404 - - - 0.00001376 51.0
TLS3_k127_6413655_6 Transposase IS66 family K07484 - - 0.0004317 43.0
TLS3_k127_6413926_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003218 271.0
TLS3_k127_6413926_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000005542 223.0
TLS3_k127_6413926_3 regulation of translation K03530 - - 0.0000000000000000000000000000000000000000003157 159.0
TLS3_k127_6413926_4 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000004823 155.0
TLS3_k127_6413926_5 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000000000000000000000000000000001471 134.0
TLS3_k127_6435976_0 AAA ATPase domain - - - 1.389e-251 808.0
TLS3_k127_6435976_1 membrane K13277,K15125,K15539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003417 278.0
TLS3_k127_6435976_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01637 - 4.1.3.1 0.0000000000000000000000000000000000008039 161.0
TLS3_k127_6473672_0 Elements of external origin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 446.0
TLS3_k127_6473672_1 nitric oxide dioxygenase activity K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000002446 226.0
TLS3_k127_6475019_0 alpha-ribazole phosphatase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0 1084.0
TLS3_k127_6482475_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000002949 104.0
TLS3_k127_6482475_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000002503 98.0
TLS3_k127_6482475_2 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.0000000000877 74.0
TLS3_k127_6482475_3 Methionine biosynthesis protein MetW - - - 0.0000002805 57.0
TLS3_k127_6484205_0 Multicopper oxidase type 1 - - - 1.598e-241 766.0
TLS3_k127_6484205_1 Copper resistance protein B precursor (CopB) K07233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 314.0
TLS3_k127_6484205_3 Uncharacterised BCR, YnfA/UPF0060 family - - - 0.000000000000000000000000000000000000000001318 158.0
TLS3_k127_6484205_4 - - - - 0.000000000000000000000000000000000000000001584 158.0
TLS3_k127_6490602_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 6.28e-213 667.0
TLS3_k127_6490602_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 3.78e-197 621.0
TLS3_k127_6490602_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 394.0
TLS3_k127_6490602_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 294.0
TLS3_k127_6490602_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002583 275.0
TLS3_k127_6490602_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000009411 240.0
TLS3_k127_6490602_6 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000001277 211.0
TLS3_k127_6490602_8 YGGT family K02221 - - 0.0000000000000000000000000000000006604 136.0
TLS3_k127_6490602_9 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.000000000000000000000005928 105.0
TLS3_k127_6521836_0 radical SAM domain protein - - - 0.0 1105.0
TLS3_k127_6521836_1 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000003864 151.0
TLS3_k127_6521836_2 addiction module antidote protein - - - 0.0000000000000000000000000001564 117.0
TLS3_k127_6521836_3 Helix-turn-helix K21498 - - 0.0004604 43.0
TLS3_k127_6530039_0 WD40-like Beta Propeller Repeat K03641 - - 1.934e-217 681.0
TLS3_k127_6530039_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.041e-202 649.0
TLS3_k127_6530039_10 energy transducer activity K03646,K03832 - - 0.0000000000000000000000000000000000000000000000009065 181.0
TLS3_k127_6530039_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000001104 50.0
TLS3_k127_6530039_2 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 546.0
TLS3_k127_6530039_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 443.0
TLS3_k127_6530039_4 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 376.0
TLS3_k127_6530039_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 377.0
TLS3_k127_6530039_6 Transposase K01991,K02557,K07161,K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 329.0
TLS3_k127_6530039_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 289.0
TLS3_k127_6530039_8 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001144 273.0
TLS3_k127_6530039_9 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000002193 233.0
TLS3_k127_6540616_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 1561.0
TLS3_k127_6540616_1 Histidine kinase - - - 8.444e-314 973.0
TLS3_k127_6540616_2 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 468.0
TLS3_k127_6540616_3 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 419.0
TLS3_k127_6540616_4 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 389.0
TLS3_k127_6540616_5 antisigma factor binding K03598 - - 0.0001226 49.0
TLS3_k127_6547522_0 cytochrome p450 - - - 3.364e-228 717.0
TLS3_k127_6547522_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 1.31e-205 654.0
TLS3_k127_6547522_10 Zn peptidase - - - 0.0000000000000000000000000000000000000001696 151.0
TLS3_k127_6547522_11 protein secretion K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000005926 138.0
TLS3_k127_6547522_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000001006 72.0
TLS3_k127_6547522_2 Phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 318.0
TLS3_k127_6547522_3 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 311.0
TLS3_k127_6547522_4 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007028 282.0
TLS3_k127_6547522_5 metal cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002375 276.0
TLS3_k127_6547522_6 Ubiquinol--cytochrome c reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006184 235.0
TLS3_k127_6547522_7 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000003376 198.0
TLS3_k127_6580611_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 367.0
TLS3_k127_6580611_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007864 258.0
TLS3_k127_6580611_11 nitrogen fixation sensor protein fixL K14986 - 2.7.13.3 0.0000009011 59.0
TLS3_k127_6580611_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008706 265.0
TLS3_k127_6580611_4 UPF0391 membrane protein - - - 0.00000000000009344 72.0
TLS3_k127_6580611_5 nuclear chromosome segregation - - - 0.00000000004396 68.0
TLS3_k127_6580611_7 Beta/Gamma crystallin - - - 0.000000002832 63.0
TLS3_k127_6580611_9 Beta/Gamma crystallin - - - 0.000000008267 63.0
TLS3_k127_6611297_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 3.964e-205 647.0
TLS3_k127_6611297_1 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 9.861e-200 634.0
TLS3_k127_6611297_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 537.0
TLS3_k127_6611297_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 440.0
TLS3_k127_6611297_4 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000005059 215.0
TLS3_k127_6611297_5 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000175 189.0
TLS3_k127_6611297_6 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000003669 55.0
TLS3_k127_662290_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 571.0
TLS3_k127_662290_1 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 412.0
TLS3_k127_662290_2 Glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 403.0
TLS3_k127_662290_3 alpha amylase catalytic K05343 - 3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 369.0
TLS3_k127_662290_4 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000004611 241.0
TLS3_k127_6650500_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 397.0
TLS3_k127_6650500_1 GDP metabolic process K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000001733 187.0
TLS3_k127_6650500_2 Protein of unknown function DUF262 - - - 0.000000000009902 69.0
TLS3_k127_6650500_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000928 50.0
TLS3_k127_6669351_0 thiamine transport K02011 - - 7.708e-222 700.0
TLS3_k127_6669351_1 iron ion homeostasis K02012 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 501.0
TLS3_k127_6669351_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 507.0
TLS3_k127_6669351_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 294.0
TLS3_k127_6669351_4 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001483 269.0
TLS3_k127_6669351_6 Protein of unknown function DUF86 - - - 0.000003781 49.0
TLS3_k127_6669351_7 ATPase activity K02010 - 3.6.3.30 0.0003134 46.0
TLS3_k127_6681436_0 Type II/IV secretion system protein K02669 - - 7.099e-202 633.0
TLS3_k127_6681436_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0030312,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 480.0
TLS3_k127_6681436_2 twitching motility protein K02670 - - 0.000000000000000000000000000000000001683 139.0
TLS3_k127_6681436_3 cell envelope organization K05807,K08309 - - 0.0000007529 52.0
TLS3_k127_6689591_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 4.599e-228 711.0
TLS3_k127_6689591_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 289.0
TLS3_k127_6689591_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000002466 231.0
TLS3_k127_6689591_3 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000002119 211.0
TLS3_k127_6689591_5 peptidyl-tyrosine sulfation - - - 0.00001083 51.0
TLS3_k127_6744619_0 amine dehydrogenase activity - - - 0.0 1722.0
TLS3_k127_6744619_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.539e-301 931.0
TLS3_k127_6744619_10 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000000000000000005274 207.0
TLS3_k127_6744619_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.094e-266 830.0
TLS3_k127_6744619_3 amine oxidase K00276 - 1.4.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 569.0
TLS3_k127_6744619_4 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 386.0
TLS3_k127_6744619_6 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 356.0
TLS3_k127_6750244_0 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000002972 233.0
TLS3_k127_6750244_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000001296 91.0
TLS3_k127_677036_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 384.0
TLS3_k127_677036_1 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 317.0
TLS3_k127_677036_3 Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family K00326 GO:0000166,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004128,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005783,GO:0005886,GO:0006091,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0012505,GO:0016020,GO:0016070,GO:0016491,GO:0016651,GO:0016653,GO:0019867,GO:0022900,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0098588,GO:0098805,GO:1901265,GO:1901360,GO:1901363 1.6.2.2 0.00000000000000000000000000000000000000000000005497 178.0
TLS3_k127_677036_5 Domain of unknown function (DUF1844) - - - 0.000000000000002503 78.0
TLS3_k127_677036_6 beta-lactamase activity K07126 - - 0.000001442 59.0
TLS3_k127_677458_0 STAS-like domain of unknown function (DUF4325) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 520.0
TLS3_k127_677458_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000004616 212.0
TLS3_k127_677458_10 Protein of unknown function (DUF2283) - - - 0.000000002785 61.0
TLS3_k127_677458_11 phage envelope protein - - - 0.0000003597 53.0
TLS3_k127_677458_2 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000000000000006202 140.0
TLS3_k127_677458_3 PFAM nuclease (SNase domain protein) - - - 0.000000000000000000000000000000000007769 142.0
TLS3_k127_677458_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000000001446 134.0
TLS3_k127_677458_5 phage envelope protein - - - 0.000000000000000000000000000001307 123.0
TLS3_k127_677458_6 - - - - 0.00000000000000000000000006134 110.0
TLS3_k127_677458_7 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000003871 105.0
TLS3_k127_677458_8 Protein of unknown function (DUF2283) - - - 0.00000000000000000008103 91.0
TLS3_k127_6777326_0 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 336.0
TLS3_k127_6777326_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007538 274.0
TLS3_k127_6777326_2 transmembrane transporter activity K03535 - - 0.0000000000000000000000000000000000000000009229 159.0
TLS3_k127_6777326_3 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000005766 132.0
TLS3_k127_678203_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 492.0
TLS3_k127_678203_1 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 342.0
TLS3_k127_678203_11 sequence-specific DNA binding K07726 - - 0.00004046 47.0
TLS3_k127_678203_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 323.0
TLS3_k127_678203_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000009969 179.0
TLS3_k127_678203_4 Domain of unknown function (DUF4160) - - - 0.0000000000000000000000000000000000000000002389 161.0
TLS3_k127_678203_5 - - - - 0.0000000000000000000000000000000000003895 141.0
TLS3_k127_678203_6 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000000003706 137.0
TLS3_k127_678203_7 Lipocalin-like domain - - - 0.00000000000000002243 83.0
TLS3_k127_678203_8 sequence-specific DNA binding K07726 - - 0.00000000000002243 78.0
TLS3_k127_678203_9 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.00000000005002 63.0
TLS3_k127_6783064_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.451e-312 968.0
TLS3_k127_6783064_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 9.594e-252 786.0
TLS3_k127_6783064_10 23S rRNA-intervening sequence protein - - - 0.0000000000000000000009856 98.0
TLS3_k127_6783064_2 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 542.0
TLS3_k127_6783064_3 Rieske (2fe-2S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 482.0
TLS3_k127_6783064_4 Formiminotransferase domain K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 447.0
TLS3_k127_6783064_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 308.0
TLS3_k127_6783064_6 uroporphyrinogen-III synthase activity K01719,K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000004513 263.0
TLS3_k127_6783064_7 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000005875 201.0
TLS3_k127_6783064_9 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000003398 152.0
TLS3_k127_678445_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1406.0
TLS3_k127_678445_1 Bacterial regulatory protein, Fis family K07715 - - 1.091e-233 730.0
TLS3_k127_678445_10 Protein of unknown function (DUF423) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000004054 145.0
TLS3_k127_678445_11 sequence-specific DNA binding - - - 0.00000000000000000000000000000003799 127.0
TLS3_k127_678445_13 Polymer-forming cytoskeletal - - - 0.000000000000000000000000002537 116.0
TLS3_k127_678445_15 - K21495 - - 0.00000000000000000003153 93.0
TLS3_k127_678445_16 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.00000000005002 63.0
TLS3_k127_678445_17 nuclease activity K18828 - - 0.0000000001027 63.0
TLS3_k127_678445_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.95e-228 717.0
TLS3_k127_678445_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 561.0
TLS3_k127_678445_4 Alpha/beta hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 352.0
TLS3_k127_678445_6 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007358 248.0
TLS3_k127_678445_7 - K07184,K07777,K12065,K13527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000007624 208.0
TLS3_k127_6790512_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 385.0
TLS3_k127_6790512_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000002229 245.0
TLS3_k127_6790512_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000000000000000000000000000000001135 167.0
TLS3_k127_6882063_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006947 280.0
TLS3_k127_6882063_1 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000003048 217.0
TLS3_k127_6882063_2 - - - - 0.0000000000000000000000000000000000000000000000000000000003993 208.0
TLS3_k127_6882063_3 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000001425 84.0
TLS3_k127_6897059_0 CHAT domain - - - 1.253e-254 808.0
TLS3_k127_6897059_1 hemolysin activation secretion protein - - - 1.088e-244 768.0
TLS3_k127_6897059_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 302.0
TLS3_k127_6897059_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002391 248.0
TLS3_k127_6897059_4 domain, Protein - - - 0.000000000000000000000000000000004528 134.0
TLS3_k127_6897059_5 PhoQ Sensor - - - 0.00000000000000000000005998 102.0
TLS3_k127_6910500_0 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000001377 201.0
TLS3_k127_6910500_1 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000002284 86.0
TLS3_k127_6931873_0 ABC transporter K06158 - - 1.523e-293 911.0
TLS3_k127_6931873_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000001682 94.0
TLS3_k127_6940757_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 2.191e-270 841.0
TLS3_k127_6940757_1 FAD binding domain K00278 - 1.4.3.16 6.498e-254 793.0
TLS3_k127_6940757_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 460.0
TLS3_k127_6940757_11 Protein of unknown function (DUF692) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 446.0
TLS3_k127_6940757_12 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 428.0
TLS3_k127_6940757_13 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 400.0
TLS3_k127_6940757_14 Magnesium transport protein CorA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 392.0
TLS3_k127_6940757_15 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 371.0
TLS3_k127_6940757_16 tRNA processing K06864,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 366.0
TLS3_k127_6940757_17 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01665 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 364.0
TLS3_k127_6940757_18 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 325.0
TLS3_k127_6940757_19 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 283.0
TLS3_k127_6940757_2 Endoribonuclease that initiates mRNA decay K18682 - - 5.243e-253 792.0
TLS3_k127_6940757_21 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002309 280.0
TLS3_k127_6940757_22 signal-transduction protein containing cAMP-binding and CBS domains K00031,K14446 - 1.1.1.42,1.3.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000001708 269.0
TLS3_k127_6940757_23 Magnesium transport protein CorA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007483 260.0
TLS3_k127_6940757_24 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002689 252.0
TLS3_k127_6940757_25 maF-like protein K03215,K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 0.00000000000000000000000000000000000000000000000002638 186.0
TLS3_k127_6940757_26 CHAD - - - 0.000000000000000000000000000000000000000000000008871 190.0
TLS3_k127_6940757_28 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000000000000000006542 156.0
TLS3_k127_6940757_29 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000003561 149.0
TLS3_k127_6940757_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.834e-235 746.0
TLS3_k127_6940757_30 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000001269 148.0
TLS3_k127_6940757_32 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000001965 134.0
TLS3_k127_6940757_33 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000001519 127.0
TLS3_k127_6940757_34 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000000000000000000000001126 117.0
TLS3_k127_6940757_36 hydrolase activity, acting on ester bonds - - - 0.00000000000003151 74.0
TLS3_k127_6940757_4 Transglycosylase SLT domain K08309 - - 6.406e-231 738.0
TLS3_k127_6940757_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 2.767e-218 685.0
TLS3_k127_6940757_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 2.895e-209 659.0
TLS3_k127_6940757_7 Bacterial protein of unknown function (DUF839) K07093 - - 1.034e-204 657.0
TLS3_k127_6940757_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 508.0
TLS3_k127_6940757_9 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 473.0
TLS3_k127_6946449_0 Pilus formation protein N terminal region K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 486.0
TLS3_k127_6946449_1 Flp pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000004609 208.0
TLS3_k127_6946449_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000002714 204.0
TLS3_k127_6946449_3 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000002609 141.0
TLS3_k127_6946449_4 PFAM Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.0000000000000000000000000884 113.0
TLS3_k127_6946449_5 PFAM TadE family protein - - - 0.00000000000000000000003572 104.0
TLS3_k127_6946449_6 Flp/Fap pilin component K02651 - - 0.00000174 51.0
TLS3_k127_6947555_0 Sterile alpha motif. - - - 0.0 1424.0
TLS3_k127_6947555_1 ABC1 family K03688 - - 0.0 1018.0
TLS3_k127_6947555_10 - - - - 0.00000000000000000000000000000000000000000000000007183 181.0
TLS3_k127_6947555_12 tRNA 3'-trailer cleavage - - - 0.00000000000000000000007265 103.0
TLS3_k127_6947555_13 SnoaL-like domain - - - 0.0000000000000000000002997 101.0
TLS3_k127_6947555_15 DJ-1/PfpI family - - - 0.00000000000007685 77.0
TLS3_k127_6947555_2 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 430.0
TLS3_k127_6947555_3 TrkA-N domain K03455,K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 413.0
TLS3_k127_6947555_4 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 391.0
TLS3_k127_6947555_5 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 337.0
TLS3_k127_6947555_6 protein disulfide oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001159 268.0
TLS3_k127_6947555_7 catechol 2,3-dioxygenase activity K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 267.0
TLS3_k127_6947555_8 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000004895 256.0
TLS3_k127_6968699_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 514.0
TLS3_k127_6968699_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 494.0
TLS3_k127_6968699_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 476.0
TLS3_k127_6968699_3 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000001284 185.0
TLS3_k127_6969835_0 PhoQ Sensor - - - 5.249e-247 793.0
TLS3_k127_6969835_1 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000000001066 168.0
TLS3_k127_6969835_2 precorrin-2 dehydrogenase activity K02302,K02304 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000172 70.0
TLS3_k127_6979984_0 Sigma-54 interaction domain K07714 - - 4.225e-245 766.0
TLS3_k127_6979984_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 550.0
TLS3_k127_6979984_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000984 291.0
TLS3_k127_6979984_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000003781 172.0
TLS3_k127_6987990_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 546.0
TLS3_k127_6987990_1 pilus assembly protein PilW K02672 - - 0.0000000000000000000000000000000000000000000000000001646 201.0
TLS3_k127_6987990_3 type IV pilus modification protein PilV K02671,K02681,K10927 - - 0.000000000000000000000008199 108.0
TLS3_k127_6987990_4 protein transport across the cell outer membrane - - - 0.00000000001252 71.0
TLS3_k127_6997743_0 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 1.755e-259 806.0
TLS3_k127_6997743_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 589.0
TLS3_k127_6997743_2 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 444.0
TLS3_k127_6997743_3 PIN domain - - - 0.000000000000000002877 88.0
TLS3_k127_6997743_4 SpoVT / AbrB like domain - - - 0.0000000000000939 73.0
TLS3_k127_6997743_5 hmm pf01609 - - - 0.000001178 56.0
TLS3_k127_7003034_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 584.0
TLS3_k127_7003034_1 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 344.0
TLS3_k127_7003034_2 response regulator K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001259 279.0
TLS3_k127_7003034_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001771 265.0
TLS3_k127_7003034_4 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000002032 186.0
TLS3_k127_7003034_5 - - - - 0.000000000000000000000000002801 113.0
TLS3_k127_7003034_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000002484 78.0
TLS3_k127_7003034_7 Putative zinc-finger - - - 0.0000001424 58.0
TLS3_k127_7044239_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 1.348e-260 811.0
TLS3_k127_7044239_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 5.259e-228 711.0
TLS3_k127_7044239_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 585.0
TLS3_k127_7044239_3 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 458.0
TLS3_k127_7044239_4 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 456.0
TLS3_k127_7052444_0 Uncharacterized ACR, YdiU/UPF0061 family K08997 - - 8.821e-206 645.0
TLS3_k127_7052444_1 Uncharacterized conserved protein (DUF2294) - - - 0.000000000000000000000000000000000000000000001887 170.0
TLS3_k127_7052444_2 Na H antiporter - - - 0.00000004684 57.0
TLS3_k127_7054206_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 582.0
TLS3_k127_7054206_1 Sulfate permease family - - - 0.00000000000000000000000000000000000000000000000000000000001521 209.0
TLS3_k127_7054206_2 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000001722 161.0
TLS3_k127_7054206_3 Universal stress protein family - - - 0.0000000000000000000000000000000008615 134.0
TLS3_k127_7063684_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.0 1126.0
TLS3_k127_7063684_1 Elongation factor G C-terminus K06207 - - 0.0 1047.0
TLS3_k127_7063684_10 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001488 279.0
TLS3_k127_7063684_11 DnaJ molecular chaperone homology domain K04082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006479 282.0
TLS3_k127_7063684_12 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000161 273.0
TLS3_k127_7063684_13 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001212 238.0
TLS3_k127_7063684_15 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000000000000000000000000000000000000000000000000004958 217.0
TLS3_k127_7063684_16 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000008532 199.0
TLS3_k127_7063684_17 Divalent cation transporter K06213 - - 0.0000000000000000000000000000000000000000000000000004357 196.0
TLS3_k127_7063684_18 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000006138 179.0
TLS3_k127_7063684_19 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.000000000000000000000000000000000000000001446 160.0
TLS3_k127_7063684_2 Hsp70 protein K04043,K04044 - - 2.169e-318 983.0
TLS3_k127_7063684_20 - - - - 0.0000000000000000000000000000000000000002076 154.0
TLS3_k127_7063684_22 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000388 154.0
TLS3_k127_7063684_23 - - - - 0.000000000000000000000000000000001266 135.0
TLS3_k127_7063684_24 Iron-sulphur cluster assembly - - - 0.00000000000000000000000000000002704 128.0
TLS3_k127_7063684_25 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000001213 128.0
TLS3_k127_7063684_27 cheY-homologous receiver domain - - - 0.0000000000000000001372 96.0
TLS3_k127_7063684_29 Hpt domain - - - 0.000000000007848 70.0
TLS3_k127_7063684_3 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 610.0
TLS3_k127_7063684_30 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000008929 53.0
TLS3_k127_7063684_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 599.0
TLS3_k127_7063684_6 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 338.0
TLS3_k127_7063684_7 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 322.0
TLS3_k127_7063684_8 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 321.0
TLS3_k127_7063684_9 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 287.0
TLS3_k127_7076684_0 Sugar efflux transporter for intercellular exchange - - - 0.0000000000000000000000000000000000004231 143.0
TLS3_k127_7076684_2 Histidine kinase K03406 - - 0.000000004378 57.0
TLS3_k127_7081437_0 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000008913 210.0
TLS3_k127_7081437_1 peroxiredoxin activity - - - 0.0000000000000000001122 93.0
TLS3_k127_7081437_2 peroxiredoxin activity - - - 0.000000000000001956 77.0
TLS3_k127_7127072_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 4.3e-322 1007.0
TLS3_k127_7127072_1 photosynthesis K02453,K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 518.0
TLS3_k127_7127072_10 - - - - 0.0000000000000000000003924 98.0
TLS3_k127_7127072_11 - - - - 0.0000000002266 64.0
TLS3_k127_7127072_13 Protein of unknown function (DUF2971) - - - 0.0000001146 59.0
TLS3_k127_7127072_14 Transposase IS200 like - - - 0.00002812 46.0
TLS3_k127_7127072_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 400.0
TLS3_k127_7127072_3 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 325.0
TLS3_k127_7127072_4 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000005234 213.0
TLS3_k127_7127072_5 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000002856 166.0
TLS3_k127_7127072_6 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000004171 143.0
TLS3_k127_7127072_7 Protein of unknown function (DUF2971) - - - 0.0000000000000000000000000002931 122.0
TLS3_k127_7127072_8 Helix-turn-helix domain - - - 0.000000000000000000000000007517 114.0
TLS3_k127_715290_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 8.425e-317 995.0
TLS3_k127_715290_1 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000002031 229.0
TLS3_k127_715290_2 peptidase - - - 0.0000000000000000001378 93.0
TLS3_k127_715290_3 Rieske [2Fe-2S] domain - - - 0.000000000000000005701 84.0
TLS3_k127_715290_4 Protein of unknown function (DUF3309) - - - 0.00000000000000001964 82.0
TLS3_k127_715290_6 Protein of unknown function (DUF1328) - - - 0.00000000008849 63.0
TLS3_k127_715290_7 Belongs to the UPF0337 (CsbD) family - - - 0.0000000003294 63.0
TLS3_k127_7231577_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.084e-280 867.0
TLS3_k127_7231577_1 choline dehydrogenase activity K08261 - 1.1.99.21 1.129e-263 822.0
TLS3_k127_7231577_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 351.0
TLS3_k127_7231577_11 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 305.0
TLS3_k127_7231577_12 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005236 264.0
TLS3_k127_7231577_13 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001213 257.0
TLS3_k127_7231577_14 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004931 241.0
TLS3_k127_7231577_15 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000001845 228.0
TLS3_k127_7231577_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000001146 228.0
TLS3_k127_7231577_17 Protein conserved in bacteria K11719 - - 0.0000000000000000000000000000000000000000000000000000000000001398 217.0
TLS3_k127_7231577_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000004807 203.0
TLS3_k127_7231577_19 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001811 200.0
TLS3_k127_7231577_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 1.424e-226 711.0
TLS3_k127_7231577_20 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000000000000000000000000000000008451 203.0
TLS3_k127_7231577_21 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000009719 196.0
TLS3_k127_7231577_22 - - - - 0.000000000000000000000000000000000000000000000000000001646 194.0
TLS3_k127_7231577_23 OstA-like protein K09774 - - 0.000000000000000000000000000000000000004638 153.0
TLS3_k127_7231577_24 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000001869 135.0
TLS3_k127_7231577_25 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000001246 133.0
TLS3_k127_7231577_26 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K13640,K18997 - - 0.00000000000000002447 83.0
TLS3_k127_7231577_27 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000005788 69.0
TLS3_k127_7231577_3 Secretin and TonB N terminus short domain K02666 - - 4.415e-210 673.0
TLS3_k127_7231577_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 563.0
TLS3_k127_7231577_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 575.0
TLS3_k127_7231577_6 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 503.0
TLS3_k127_7231577_7 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 437.0
TLS3_k127_7231577_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 434.0
TLS3_k127_7231577_9 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 392.0
TLS3_k127_7238856_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 556.0
TLS3_k127_7238856_1 - - - - 0.0003328 44.0
TLS3_k127_7242721_1 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000009319 66.0
TLS3_k127_7268900_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0003452 53.0
TLS3_k127_7273476_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 560.0
TLS3_k127_7273476_1 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 546.0
TLS3_k127_7273476_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 520.0
TLS3_k127_7273476_3 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 285.0
TLS3_k127_7273476_4 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001558 286.0
TLS3_k127_7273476_5 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.000000000000000000000000000000000003329 138.0
TLS3_k127_7296815_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 3.705e-321 994.0
TLS3_k127_7296815_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 388.0
TLS3_k127_7296815_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 348.0
TLS3_k127_7347385_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.924e-221 690.0
TLS3_k127_7347385_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 6.28e-213 667.0
TLS3_k127_7347385_10 Transposase K02557,K07484,K13924,K21471 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000442 127.0
TLS3_k127_7347385_12 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.000000000001324 72.0
TLS3_k127_7347385_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 593.0
TLS3_k127_7347385_3 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 520.0
TLS3_k127_7347385_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 461.0
TLS3_k127_7347385_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 457.0
TLS3_k127_7347385_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 419.0
TLS3_k127_7347385_7 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 356.0
TLS3_k127_7347385_8 cell adhesion K02650 - - 0.0000000000000000000000000000000000000000000000000000000000001269 218.0
TLS3_k127_7360636_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K19585 - - 0.0 1498.0
TLS3_k127_7360636_1 Major facilitator Superfamily K08218 - - 5.69e-241 755.0
TLS3_k127_7360636_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 559.0
TLS3_k127_7360636_3 electron transfer activity K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 397.0
TLS3_k127_7360636_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 344.0
TLS3_k127_7360636_5 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K00567,K01247 - 2.1.1.63,3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 304.0
TLS3_k127_7360636_6 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001596 269.0
TLS3_k127_7360636_7 positive regulation of type IV pilus biogenesis K07343 - - 0.0000000000000000000000000000000002324 134.0
TLS3_k127_7376389_0 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005381 274.0
TLS3_k127_7376389_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000000000000000000026 198.0
TLS3_k127_7376389_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000003742 196.0
TLS3_k127_7376389_3 AMP binding K11932 - - 0.0000000000000000000000000000000000000000003231 163.0
TLS3_k127_7376389_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000006676 104.0
TLS3_k127_7376389_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000002088 76.0
TLS3_k127_7384911_0 poly(3-hydroxybutyrate) depolymerase activity K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 447.0
TLS3_k127_7384911_1 Class ii aldolase K01628,K18847 - 2.2.1.8,4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 376.0
TLS3_k127_7384911_2 Pup-ligase protein K13571 - 6.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000005703 265.0
TLS3_k127_7401275_0 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000000000008986 194.0
TLS3_k127_7404899_0 phosphorelay signal transduction system K02282,K02482,K04757,K20977 - 2.7.11.1,2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000003378 239.0
TLS3_k127_7404899_1 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000000004923 163.0
TLS3_k127_7404899_2 Type II secretion system (T2SS), protein M K02462 - - 0.000000000000007206 83.0
TLS3_k127_7404899_3 Type II secretion system (T2SS), protein J K02459 - - 0.0000008305 58.0
TLS3_k127_7404899_5 Type IV pilus assembly protein PilM; K02662 - - 0.0002629 53.0
TLS3_k127_7404899_6 type IV pilus modification protein PilV K02458,K02671 - - 0.000776 48.0
TLS3_k127_7429757_0 intracellular signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 379.0
TLS3_k127_7429757_1 ATP-dependent transcriptional regulator K03556 - - 0.0000000000000006317 83.0
TLS3_k127_745195_0 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 352.0
TLS3_k127_745195_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 342.0
TLS3_k127_745195_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
TLS3_k127_7459722_0 Putative modulator of DNA gyrase K03568 - - 5.706e-246 765.0
TLS3_k127_7459722_1 Putative modulator of DNA gyrase K03592 - - 8.259e-198 625.0
TLS3_k127_7459722_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 606.0
TLS3_k127_7459722_3 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 583.0
TLS3_k127_7459722_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 390.0
TLS3_k127_7459722_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000003209 207.0
TLS3_k127_7459722_7 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000461 205.0
TLS3_k127_7459722_8 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000007338 75.0
TLS3_k127_7496933_0 short chain amide porin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 390.0
TLS3_k127_7496933_1 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001058 246.0
TLS3_k127_7496933_2 urea ABC transporter, ATP-binding protein K11963 - - 0.0000000000000000008793 91.0
TLS3_k127_7506410_0 Pfam:HipA_N K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 377.0
TLS3_k127_7506410_1 transcriptional regulator, XRE family - - - 0.0000000000000000000000000000005066 125.0
TLS3_k127_7506410_2 - - - - 0.00000004211 54.0
TLS3_k127_7511233_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000001385 171.0
TLS3_k127_7511233_1 Polynucleotide kinase 3 phosphatase - - - 0.00000000000000000000000000000000006108 141.0
TLS3_k127_7511233_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K10936,K16079 - - 0.00000002172 63.0
TLS3_k127_7511233_3 PRC-barrel domain - - - 0.0000008746 52.0
TLS3_k127_7511233_4 YtxH-like protein - - - 0.00005166 50.0
TLS3_k127_7552909_0 Metallopeptidase family M24 K01262 - 3.4.11.9 2.415e-197 620.0
TLS3_k127_7552909_1 Protein involved in outer membrane biogenesis K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 617.0
TLS3_k127_7552909_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00322,K00382 - 1.6.1.1,1.8.1.4 0.0000000000000000000000000000000000000000001871 160.0
TLS3_k127_7569763_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 532.0
TLS3_k127_7588125_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 410.0
TLS3_k127_7588125_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 288.0
TLS3_k127_7592849_0 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 326.0
TLS3_k127_7592849_1 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001218 263.0
TLS3_k127_7592849_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000002647 214.0
TLS3_k127_7592849_3 - - - - 0.0000000000000000000002835 100.0
TLS3_k127_7596745_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.452e-235 737.0
TLS3_k127_7596745_1 Histidine kinase K00060,K07777 - 1.1.1.103,2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 543.0
TLS3_k127_7596745_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000485 228.0
TLS3_k127_7596745_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000006962 228.0
TLS3_k127_7596745_4 response regulator, receiver K02479 - - 0.000000000000000000000000000000000000000000000000000000000796 208.0
TLS3_k127_7596745_5 Cadherin-like beta sandwich domain - - - 0.00000000000000007036 86.0
TLS3_k127_7596745_6 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0016874,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.3.1.29 0.00000000009536 62.0
TLS3_k127_7619726_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 1.42e-242 754.0
TLS3_k127_7619726_1 Tetratricopeptide repeat - - - 4.513e-217 690.0
TLS3_k127_7619726_2 Histidyl-tRNA synthetase K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 392.0
TLS3_k127_7619726_3 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000000000000000005201 91.0
TLS3_k127_7642010_0 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 324.0
TLS3_k127_7642010_1 Belongs to the peptidase S1B family K07114 - - 0.00000000000000000000000000000000002831 156.0
TLS3_k127_7702231_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1289.0
TLS3_k127_7702231_1 von Willebrand factor (vWF) type A domain K02448 - - 1.525e-301 955.0
TLS3_k127_7702231_10 - - - - 0.000001094 59.0
TLS3_k127_7702231_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 488.0
TLS3_k127_7702231_3 protein histidine kinase activity K02484,K07640,K07643,K07645,K07649,K19609 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 480.0
TLS3_k127_7702231_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 358.0
TLS3_k127_7702231_5 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002401 270.0
TLS3_k127_7702231_6 ferredoxin-thioredoxin reductase activity K17892 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015979,GO:0016491,GO:0016730,GO:0022900,GO:0030385,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 1.8.7.2 0.000000000000000000000000000000000000000000000000000000000000000000004965 238.0
TLS3_k127_7702231_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000003133 219.0
TLS3_k127_7702231_9 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000000000000000000000000000002859 152.0
TLS3_k127_771627_0 Membrane - - - 0.0000000000000000000000000000000000000000000001713 174.0
TLS3_k127_771627_1 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000002855 150.0
TLS3_k127_771627_2 Predicted membrane protein (DUF2214) K08983 - - 0.0000000000000000000000000000000000002542 146.0
TLS3_k127_7720092_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 3.744e-204 644.0
TLS3_k127_7720092_2 phosphonoacetaldehyde hydrolase activity K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 321.0
TLS3_k127_7720092_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 287.0
TLS3_k127_7720092_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001398 264.0
TLS3_k127_7720092_6 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000005979 192.0
TLS3_k127_7720092_7 AntiSigma factor - - - 0.00000000000000000000000004027 111.0
TLS3_k127_7720092_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000004207 72.0
TLS3_k127_7727255_0 Diguanylate cyclase - - - 1.657e-274 865.0
TLS3_k127_7727255_1 NNMT/PNMT/TEMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001503 259.0
TLS3_k127_7727255_2 Small Multidrug Resistance protein K03297 - - 0.000945 43.0
TLS3_k127_7738021_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1089.0
TLS3_k127_7738021_1 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 609.0
TLS3_k127_7738021_2 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 319.0
TLS3_k127_7738021_3 - - - - 0.00000000000000000000002033 106.0
TLS3_k127_7738021_4 nuclease activity K06218 - - 0.00000000000000003206 83.0
TLS3_k127_7738021_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000001486 65.0
TLS3_k127_774364_0 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 417.0
TLS3_k127_774364_1 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006641 262.0
TLS3_k127_774364_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000001446 215.0
TLS3_k127_774364_3 - - - - 0.0000000000000000000000000000000000000000000000000479 185.0
TLS3_k127_774364_4 response regulator - - - 0.000000000000000000000000000000000000000007253 177.0
TLS3_k127_774364_5 Ferredoxin - - - 0.0000000000000000000000000000003005 129.0
TLS3_k127_7745017_0 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000008491 191.0
TLS3_k127_7745017_1 - - - - 0.0000000000000000000000000000000000000000000000006192 188.0
TLS3_k127_7745017_2 PFAM Calcium calmodulin dependent protein kinase II association-domain protein - - - 0.000000000000000000000000000000001964 132.0
TLS3_k127_7745590_0 Protein of unknown function (DUF1207) - - - 0.0000000000000000000000000000000000000000000000000000000000000003332 228.0
TLS3_k127_7745590_1 Domain of Unknown Function (DUF748) - - - 0.00000000000007516 85.0
TLS3_k127_7746312_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.474e-251 780.0
TLS3_k127_7746312_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 410.0
TLS3_k127_7746312_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003078 190.0
TLS3_k127_7746312_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000002417 179.0
TLS3_k127_7746312_12 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000005394 174.0
TLS3_k127_7746312_13 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000005353 171.0
TLS3_k127_7746312_14 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000001657 161.0
TLS3_k127_7746312_15 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000004844 135.0
TLS3_k127_7746312_16 30S ribosomal protein S14 K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002081 111.0
TLS3_k127_7746312_17 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000007795 81.0
TLS3_k127_7746312_18 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001725 78.0
TLS3_k127_7746312_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 331.0
TLS3_k127_7746312_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 292.0
TLS3_k127_7746312_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001647 278.0
TLS3_k127_7746312_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001104 278.0
TLS3_k127_7746312_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001041 255.0
TLS3_k127_7746312_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001338 237.0
TLS3_k127_7746312_8 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001078 221.0
TLS3_k127_7746312_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000009793 213.0
TLS3_k127_7747258_0 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 346.0
TLS3_k127_7747258_1 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
TLS3_k127_7747258_2 - - - - 0.00000000000000000000000000000006068 129.0
TLS3_k127_7747258_3 PFAM multicopper oxidase - - - 0.0000000000000000003143 93.0
TLS3_k127_7747258_4 Multicopper oxidase K08100 - 1.3.3.5 0.0000000000003581 74.0
TLS3_k127_7747258_5 Multicopper oxidase K08100 - 1.3.3.5 0.0000004941 56.0
TLS3_k127_7751386_0 Acts as a magnesium transporter K06213 - - 1.762e-223 701.0
TLS3_k127_7751386_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 326.0
TLS3_k127_7751386_2 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000000000000009326 216.0
TLS3_k127_7751386_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000787 200.0
TLS3_k127_7751386_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000004836 67.0
TLS3_k127_7752265_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K04076,K13525,K17681 - 3.4.21.53 2.05e-274 854.0
TLS3_k127_7752265_1 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 458.0
TLS3_k127_7752265_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 406.0
TLS3_k127_7752265_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 357.0
TLS3_k127_7752265_4 Cyclic peptide transporter K06160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001831 271.0
TLS3_k127_7752265_5 cellular manganese ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000001967 226.0
TLS3_k127_7752265_6 response to oxidative stress K04063 - - 0.0000000000000000000000000000000000000000000000000000000000000005681 221.0
TLS3_k127_7752265_7 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000000000000000000000001021 183.0
TLS3_k127_7752265_8 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000001959 154.0
TLS3_k127_7752265_9 Cytochrome c K12263 - - 0.000000000000000000007122 96.0
TLS3_k127_7755383_0 COGs COG3328 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 456.0
TLS3_k127_7757413_0 CHAT domain - - - 1.834e-224 716.0
TLS3_k127_7757413_1 hemolysin activation secretion protein - - - 3.996e-195 626.0
TLS3_k127_7757413_2 Common central domain of tyrosinase K00505 - 1.14.18.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 548.0
TLS3_k127_7757413_3 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 401.0
TLS3_k127_7757413_4 toxin-antitoxin pair type II binding K08591,K19159 - 2.3.1.15 0.0000000000000000000000000000000000006548 143.0
TLS3_k127_7757413_5 mRNA cleavage K19158 - - 0.00000000000000000000000000000008488 124.0
TLS3_k127_7757413_6 - - - - 0.000000000000000000005388 96.0
TLS3_k127_7765248_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 377.0
TLS3_k127_7765248_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 328.0
TLS3_k127_7765248_2 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 253.0
TLS3_k127_7765248_3 protein disulfide oxidoreductase activity K03673 - - 0.000000000000000000000000000000000000000000000000003146 187.0
TLS3_k127_7765248_5 Flagellar basal body rod FlgEFG protein C-terminal K02388 - - 0.0000000000000000000473 94.0
TLS3_k127_7768443_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.211e-296 930.0
TLS3_k127_7768443_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 4.401e-228 712.0
TLS3_k127_7768443_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 2.127e-198 623.0
TLS3_k127_7768443_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000008733 195.0
TLS3_k127_7768443_4 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.000000000000000000000000000001879 123.0
TLS3_k127_7768518_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.385e-303 933.0
TLS3_k127_7768518_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.462e-302 928.0
TLS3_k127_7768518_10 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 409.0
TLS3_k127_7768518_11 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 404.0
TLS3_k127_7768518_12 pectinesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 380.0
TLS3_k127_7768518_13 Zinc-uptake complex component A periplasmic K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 344.0
TLS3_k127_7768518_14 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 340.0
TLS3_k127_7768518_15 Histidine kinase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 321.0
TLS3_k127_7768518_16 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000001724 272.0
TLS3_k127_7768518_17 domain protein K02004,K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003582 270.0
TLS3_k127_7768518_18 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005956 241.0
TLS3_k127_7768518_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000008602 217.0
TLS3_k127_7768518_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 530.0
TLS3_k127_7768518_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000008993 217.0
TLS3_k127_7768518_21 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000001566 194.0
TLS3_k127_7768518_22 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000001408 190.0
TLS3_k127_7768518_23 chlorophyll binding K02487,K12543 - - 0.0000000000000000000000000000000000000000000000000002464 192.0
TLS3_k127_7768518_26 - K07275 - - 0.00000000000000000000000000001539 126.0
TLS3_k127_7768518_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 475.0
TLS3_k127_7768518_30 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K10936,K16079 - - 0.000002642 58.0
TLS3_k127_7768518_4 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 468.0
TLS3_k127_7768518_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 457.0
TLS3_k127_7768518_6 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 442.0
TLS3_k127_7768518_7 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 438.0
TLS3_k127_7768518_8 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 439.0
TLS3_k127_7768518_9 AAA domain, putative AbiEii toxin, Type IV TA system K09817,K09820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 423.0
TLS3_k127_7768592_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 424.0
TLS3_k127_7768592_1 lipid binding K03098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006211 261.0
TLS3_k127_7768592_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000008764 145.0
TLS3_k127_7768592_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000003209 146.0
TLS3_k127_7769753_0 Evidence 5 No homology to any previously reported sequences K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005625 291.0
TLS3_k127_7769753_1 DNA integration - - - 0.000000000000000000000000000000000000000000000000002202 186.0
TLS3_k127_7784213_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1459.0
TLS3_k127_7784213_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 306.0
TLS3_k127_7784213_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000002354 194.0
TLS3_k127_7784213_3 - - - - 0.00000000005586 67.0
TLS3_k127_7784213_4 Belongs to the SEDS family - - - 0.000006058 51.0
TLS3_k127_7813459_0 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 375.0
TLS3_k127_7813459_1 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 305.0
TLS3_k127_7813459_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000005493 166.0
TLS3_k127_7813459_3 flavodoxin nitric oxide synthase - - - 0.0000002124 53.0
TLS3_k127_7840574_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 510.0
TLS3_k127_7840574_1 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007136 281.0
TLS3_k127_7840574_2 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000002291 267.0
TLS3_k127_7858769_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.132e-202 632.0
TLS3_k127_7858769_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 342.0
TLS3_k127_7858769_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003701 274.0
TLS3_k127_7858769_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007366 270.0
TLS3_k127_7868201_0 Cytochrome c K00405 - - 3.874e-317 978.0
TLS3_k127_7868201_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.078e-256 799.0
TLS3_k127_7868201_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 1.632e-249 781.0
TLS3_k127_7868201_3 Cytochrome c K00405 - - 5.103e-210 659.0
TLS3_k127_7868201_4 Cytochrome c - - - 5.62e-198 620.0
TLS3_k127_7868201_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 527.0
TLS3_k127_7868201_6 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001832 267.0
TLS3_k127_7868201_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000004757 167.0
TLS3_k127_7868201_8 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000000008534 150.0
TLS3_k127_7876371_0 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000008576 210.0
TLS3_k127_7876371_1 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000006355 191.0
TLS3_k127_7876371_2 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000000000000000000000001147 169.0
TLS3_k127_7876371_3 Predicted membrane protein (DUF2127) - - - 0.0000001779 59.0
TLS3_k127_7876371_5 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.0000008746 52.0
TLS3_k127_7876371_6 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.000003036 50.0
TLS3_k127_7877709_0 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000001264 139.0
TLS3_k127_7877709_1 Hsp20/alpha crystallin family - - - 0.00000003565 57.0
TLS3_k127_7877709_2 Abc-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000698 50.0
TLS3_k127_7878569_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 485.0
TLS3_k127_7878569_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000008024 245.0
TLS3_k127_7878569_2 phosphate ion binding K02040 - - 0.00000000000000000000000000000000000000000000000005354 189.0
TLS3_k127_7887333_0 response regulator K02479,K07685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000409 248.0
TLS3_k127_7887333_1 RNA recognition motif - - - 0.00000000000000000000000000000000000000000000003237 171.0
TLS3_k127_7887333_7 - - - - 0.0001627 48.0
TLS3_k127_789959_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 591.0
TLS3_k127_789959_1 PFAM DegT DnrJ EryC1 StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 526.0
TLS3_k127_789959_2 -O-antigen K02847,K02849,K21003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 309.0
TLS3_k127_789959_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 301.0
TLS3_k127_7926634_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.472e-263 815.0
TLS3_k127_7926634_1 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009772 247.0
TLS3_k127_7926634_2 nitric oxide dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000006608 233.0
TLS3_k127_7926634_3 Transcriptional regulator - - - 0.0000001547 53.0
TLS3_k127_794919_0 regulator - - - 0.000000000000000000000000000000000000000000000000000001044 196.0
TLS3_k127_794919_1 COG1651 Protein-disulfide isomerase K21990 - - 0.000000000000000000000000000000000000000000005636 173.0
TLS3_k127_794919_2 Radical SAM superfamily K22226 - - 0.000000000000000000000000000000000000003286 154.0
TLS3_k127_794919_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000001852 130.0
TLS3_k127_794919_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000001368 94.0
TLS3_k127_796330_0 extracellular polysaccharide biosynthetic process K07011,K16706 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 458.0
TLS3_k127_796330_1 protein tyrosine kinase activity K08252 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 347.0
TLS3_k127_796330_2 peptidyl-tyrosine sulfation K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 298.0
TLS3_k127_7972850_0 Carboxylesterase family K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 365.0
TLS3_k127_7972850_1 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000001043 229.0
TLS3_k127_7972850_2 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000129 178.0
TLS3_k127_7972850_3 Domain of unknown function (DUF4142) K08995 - - 0.000000000000000003585 91.0
TLS3_k127_7986709_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1046.0
TLS3_k127_7986709_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1004.0
TLS3_k127_7986709_2 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 474.0
TLS3_k127_7986709_3 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 478.0
TLS3_k127_7986709_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 381.0
TLS3_k127_7986709_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 347.0
TLS3_k127_7986709_6 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000123 214.0
TLS3_k127_8014376_0 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 562.0
TLS3_k127_8014376_1 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 552.0
TLS3_k127_8014376_2 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 379.0
TLS3_k127_8014376_3 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000000000000000000000000000000000005788 210.0
TLS3_k127_8014376_4 response to nickel cation K07723 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000002578 104.0
TLS3_k127_8014376_5 Nacht domain - - - 0.000000000000000000003896 93.0
TLS3_k127_8014376_6 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000002006 87.0
TLS3_k127_80176_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 366.0
TLS3_k127_80176_1 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 370.0
TLS3_k127_80176_2 Belongs to the glutathione peroxidase family K00432,K20207 - 1.11.1.22,1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000006949 225.0
TLS3_k127_80176_3 - - - - 0.000000000000000000000000000000000003396 142.0
TLS3_k127_80176_4 Belongs to the ompA family K02557,K03286 - - 0.00000000000000000000000005158 115.0
TLS3_k127_8026994_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 543.0
TLS3_k127_8026994_1 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 437.0
TLS3_k127_8026994_2 Dodecin K09165 - - 0.000000000000000000001111 95.0
TLS3_k127_8026994_3 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0000000000000000001161 100.0
TLS3_k127_8026994_4 Protein of unknown function (DUF2459) - - - 0.0000000000000003108 87.0
TLS3_k127_8026994_5 - - - - 0.000006559 58.0
TLS3_k127_803607_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 557.0
TLS3_k127_803607_1 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 449.0
TLS3_k127_803607_2 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 420.0
TLS3_k127_803607_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 396.0
TLS3_k127_803607_4 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002309 280.0
TLS3_k127_803607_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000005664 184.0
TLS3_k127_803607_6 Protein of unknown function (DUF2905) - - - 0.000000000000000000000009952 102.0
TLS3_k127_8084348_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1508.0
TLS3_k127_8084348_1 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000576 247.0
TLS3_k127_8084348_2 - - - - 0.000000000000000000000000000000004028 134.0
TLS3_k127_8084348_4 Evidence 5 No homology to any previously reported sequences - - - 0.000005069 52.0
TLS3_k127_8112232_0 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0 1290.0
TLS3_k127_8112232_1 microcin transport K06160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004635 271.0
TLS3_k127_8149163_0 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 9.844e-243 758.0
TLS3_k127_8149163_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 324.0
TLS3_k127_8149163_2 response regulator K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 310.0
TLS3_k127_8149163_3 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000007077 216.0
TLS3_k127_8149163_4 Dodecin K09165 - - 0.0000000000000000000009558 96.0
TLS3_k127_8149163_5 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 0.0000000000000000786 83.0
TLS3_k127_8149163_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00520 - 1.16.1.1 0.00007484 49.0
TLS3_k127_8185210_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000004263 210.0
TLS3_k127_8215375_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 2.514e-206 653.0
TLS3_k127_8215375_1 phosphorelay signal transduction system K02535 - 3.5.1.108 0.00000000000000000000000000003715 119.0
TLS3_k127_8229184_0 DNA-directed DNA polymerase K02337,K14162 - 2.7.7.7 0.0 1110.0
TLS3_k127_8229184_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 314.0
TLS3_k127_8229184_2 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000779 221.0
TLS3_k127_8229184_3 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000004365 166.0
TLS3_k127_8229184_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000001327 141.0
TLS3_k127_8229184_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000404 138.0
TLS3_k127_8229184_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001587 96.0
TLS3_k127_8229184_7 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000004637 79.0
TLS3_k127_824897_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00615,K00616 - 2.2.1.1,2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 419.0
TLS3_k127_824897_1 Protein of unknown function (DUF3015) - - - 0.00000000000000000000000000000001359 132.0
TLS3_k127_824897_2 - - - - 0.0000000000000000002 94.0
TLS3_k127_824897_3 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000005592 89.0
TLS3_k127_8250451_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.564e-197 618.0
TLS3_k127_8250451_1 obsolete transcription factor activity, core RNA polymerase II binding K06959 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 360.0
TLS3_k127_8250451_2 cysteine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000007641 209.0
TLS3_k127_8253603_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - 0.0000000000000000006263 89.0
TLS3_k127_8253603_1 - - - - 0.0000006857 53.0
TLS3_k127_8253603_2 Bacteriophage CI repressor helix-turn-helix domain - - - 0.0001516 48.0
TLS3_k127_8253603_3 - - - - 0.0004205 51.0
TLS3_k127_8321724_0 amino acid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 306.0
TLS3_k127_8321724_2 Putative prokaryotic signal transducing protein - - - 0.000000000000000000003155 96.0
TLS3_k127_8321724_3 - - - - 0.00000000000002356 79.0
TLS3_k127_8321724_4 - - - - 0.00000000001735 71.0
TLS3_k127_8321724_5 - K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000003471 62.0
TLS3_k127_8321724_6 - - - - 0.00000001469 62.0
TLS3_k127_8327761_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 7.077e-224 696.0
TLS3_k127_8327761_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 2.451e-206 655.0
TLS3_k127_8327761_10 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000002257 190.0
TLS3_k127_8327761_11 belongs to the thioredoxin family K14949,K20543 - 2.7.11.1 0.000000000000000000000000000000000000000000000108 177.0
TLS3_k127_8327761_12 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000000000000000002957 169.0
TLS3_k127_8327761_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 557.0
TLS3_k127_8327761_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 455.0
TLS3_k127_8327761_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 388.0
TLS3_k127_8327761_5 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 327.0
TLS3_k127_8327761_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 316.0
TLS3_k127_8327761_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001381 282.0
TLS3_k127_8327761_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009541 275.0
TLS3_k127_8327761_9 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000001092 202.0
TLS3_k127_8342879_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.541e-274 852.0
TLS3_k127_8342879_1 Evidence 2b Function of strongly homologous gene - - - 2.135e-210 657.0
TLS3_k127_8342879_2 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 488.0
TLS3_k127_8342879_3 cell envelope organization K05807,K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008031 275.0
TLS3_k127_837083_0 Evidence 5 No homology to any previously reported sequences K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 423.0
TLS3_k127_837083_1 IPT/TIG domain - - - 0.00000000000000000000000000000000000000000002112 183.0
TLS3_k127_837083_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000005226 160.0
TLS3_k127_8424940_0 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 386.0
TLS3_k127_8424940_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 354.0
TLS3_k127_8424940_2 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000007818 200.0
TLS3_k127_8424940_3 Transposase - - - 0.000000000005895 72.0
TLS3_k127_8428892_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 424.0
TLS3_k127_8428892_1 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000001015 194.0
TLS3_k127_8448489_0 COG0659 Sulfate permease and related transporters (MFS K01673,K03321 - 4.2.1.1 1.432e-241 760.0
TLS3_k127_8448489_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.00000000008304 68.0
TLS3_k127_8489259_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 386.0
TLS3_k127_8489259_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002113 255.0
TLS3_k127_8489259_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000005571 226.0
TLS3_k127_8489259_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000001386 201.0
TLS3_k127_8489259_4 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000003564 180.0
TLS3_k127_8489259_5 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000004835 164.0
TLS3_k127_8511048_0 Alpha/beta hydrolase family K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 329.0
TLS3_k127_8511048_1 thiolester hydrolase activity K06889,K07000 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 323.0
TLS3_k127_8511048_2 Uncharacterized ACR, YdiU/UPF0061 family K08997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 304.0
TLS3_k127_8511048_4 ABC transporter transmembrane region K06148 - - 0.0000005753 52.0
TLS3_k127_8511048_5 FAD binding domain - - - 0.0003039 45.0
TLS3_k127_8556428_0 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 511.0
TLS3_k127_8556428_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 399.0
TLS3_k127_8556428_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 398.0
TLS3_k127_8556428_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 394.0
TLS3_k127_8556428_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 345.0
TLS3_k127_8556428_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 284.0
TLS3_k127_8556428_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000001722 64.0
TLS3_k127_8585201_0 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000000000000000000000000000000000000000002528 217.0
TLS3_k127_8585201_1 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000003675 187.0
TLS3_k127_8585201_2 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000002226 143.0
TLS3_k127_8585201_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000002678 102.0
TLS3_k127_8585201_5 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0003166 44.0
TLS3_k127_8585579_0 Methyl-transferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 495.0
TLS3_k127_8585579_1 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 303.0
TLS3_k127_8585579_2 Large family of predicted nucleotide-binding domains - - - 0.00000000000000003493 92.0
TLS3_k127_8585579_3 Protein of unknown function (DUF2442) - - - 0.000000000000005172 77.0
TLS3_k127_867392_0 peptidase K02557,K21471 - - 0.0000000000000002022 88.0
TLS3_k127_867392_1 SMART cyclic nucleotide-binding - - - 0.0000000002562 60.0
TLS3_k127_878284_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 511.0
TLS3_k127_878284_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000002357 222.0
TLS3_k127_880839_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.619e-238 739.0
TLS3_k127_880839_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 2.847e-206 646.0
TLS3_k127_880839_2 ATPase activity K02013,K02028,K05776 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 397.0
TLS3_k127_880839_3 RNA-DNA hybrid ribonuclease activity K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001638 289.0
TLS3_k127_880839_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000007149 151.0
TLS3_k127_880839_5 Uncharacterized ACR, COG1993 K06199,K09137 - - 0.000000000000000000000000000002707 123.0
TLS3_k127_880839_6 - - - - 0.00000000001018 75.0
TLS3_k127_911401_0 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006529 264.0
TLS3_k127_911401_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001007 230.0
TLS3_k127_911401_10 - - - - 0.000000003202 60.0
TLS3_k127_911401_13 - - - - 0.00002396 53.0
TLS3_k127_911401_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000009548 221.0
TLS3_k127_911401_3 each copy contains a frameshift at the sequence CCCCCCTTTTT and 7 copies of repeat with repeat unit SCEEP - - - 0.0000000000000000000000000000000000000000002293 166.0
TLS3_k127_911401_4 Uncharacterised protein family (UPF0158) - - - 0.0000000000000000000000000000000000000000002578 162.0
TLS3_k127_911401_5 Acetyltransferase (GNAT) domain K18816 - 2.3.1.82 0.000000000000000000000000000000000000000002148 160.0
TLS3_k127_911401_6 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000004637 158.0
TLS3_k127_911401_7 - - - - 0.0000000000000000000000000008708 116.0
TLS3_k127_911401_8 - - - - 0.00000000000000000022 89.0
TLS3_k127_911401_9 Metal binding domain of Ada K00567,K10778 GO:0001130,GO:0003674,GO:0003700,GO:0003824,GO:0003908,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006355,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016740,GO:0016741,GO:0018125,GO:0018193,GO:0018198,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044728,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070988,GO:0071704,GO:0080090,GO:0080111,GO:0090304,GO:0140110,GO:1901360,GO:1901564,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 2.1.1.63 0.0000000000008904 72.0
TLS3_k127_927056_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 376.0
TLS3_k127_927056_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002802 280.0
TLS3_k127_946016_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K08068 - 3.2.1.183,5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 499.0
TLS3_k127_946016_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000832 192.0
TLS3_k127_946016_2 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.00005899 51.0
TLS3_k127_948672_0 denitrification pathway - - - 4.714e-221 691.0
TLS3_k127_948672_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 517.0
TLS3_k127_948672_2 thiosulfate sulfurtransferase activity K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 453.0
TLS3_k127_948672_3 HemY protein K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000002094 177.0
TLS3_k127_948672_4 Small metal-binding protein - - - 0.0005356 50.0
TLS3_k127_971709_0 silver ion transport K07787,K15726 - - 6.661e-282 901.0
TLS3_k127_971709_1 Glutathione S-transferase K00799,K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7,2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 529.0
TLS3_k127_971709_10 Macro domain - - - 0.0000000000000000000009762 97.0
TLS3_k127_971709_11 Peptidase dimerisation domain - - - 0.0000000000000000006697 91.0
TLS3_k127_971709_12 GCN5 family acetyltransferase - - - 0.00005974 51.0
TLS3_k127_971709_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 433.0
TLS3_k127_971709_3 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 384.0
TLS3_k127_971709_4 signal-transduction protein containing cAMP-binding and CBS domains K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007015 275.0
TLS3_k127_971709_5 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004509 261.0
TLS3_k127_971709_6 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000004661 240.0
TLS3_k127_971709_7 Macro domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005319 226.0
TLS3_k127_971709_8 PFAM Endonuclease exonuclease phosphatase K06896 - 3.1.3.90 0.0000000000000000000000000000000000000000000000000000005945 207.0
TLS3_k127_971709_9 Lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000008542 188.0
TLS3_k127_972868_0 ROS/MUCR transcriptional regulator protein - - - 0.00000000000000004417 88.0
TLS3_k127_973516_0 Protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 436.0
TLS3_k127_973516_1 Domain of unknown function (DUF3482) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 334.0
TLS3_k127_973516_2 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000002288 194.0
TLS3_k127_980072_0 sulfate adenylyltransferase (ATP) activity K00860,K00955,K00956 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 329.0
TLS3_k127_980072_1 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000002997 109.0
TLS3_k127_980072_2 NADH ubiquinone oxidoreductase 41 kD complex I subunit - - - 0.00000000000000000008007 103.0
TLS3_k127_98077_0 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 387.0
TLS3_k127_98077_1 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 305.0
TLS3_k127_98077_2 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000141 287.0
TLS3_k127_98077_3 IMP dehydrogenase activity K07182 - - 0.0000000000000000000000000000000000000000000000000000000003762 206.0
TLS3_k127_98077_4 IMP dehydrogenase activity K07182 - - 0.00000000000000000000000000000000000707 141.0
TLS3_k127_98077_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000009518 129.0
TLS3_k127_98077_6 Cation transporter/ATPase, N-terminus K01537,K01539 - 3.6.3.8,3.6.3.9 0.00000000000000000002906 93.0
TLS3_k127_98077_8 alcohol dehydrogenase K00001,K13953,K13979 - 1.1.1.1 0.000000000000001184 81.0
TLS3_k127_98077_9 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.0000000000001684 73.0