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Overview

ID MAG04108
Name WH2_bin.10
Sample SMP0107
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Ferrovibrionales
Family Ferrovibrionaceae
Genus JAFKFH01
Species
Assembly information
Completeness (%) 98.18
Contamination (%) 4.13
GC content (%) 68.0
N50 (bp) 24,542
Genome size (bp) 7,008,391

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes6621

Gene name Description KEGG GOs EC E-value Score Sequence
WH2_k127_10034690_0 ATPases associated with a variety of cellular activities K06147 - - 1.217e-292 910.0
WH2_k127_10034690_1 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 5.901e-240 748.0
WH2_k127_10034690_10 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 405.0
WH2_k127_10034690_11 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 410.0
WH2_k127_10034690_12 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 382.0
WH2_k127_10034690_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 339.0
WH2_k127_10034690_14 Methyladenine glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 334.0
WH2_k127_10034690_15 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 314.0
WH2_k127_10034690_16 - K19200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000371 291.0
WH2_k127_10034690_17 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000001689 270.0
WH2_k127_10034690_18 Tetracyclin repressor, C-terminal all-alpha domain K18476 - - 0.00000000000000000000000000000000000000000000000000000000000000000001855 238.0
WH2_k127_10034690_19 glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000005208 228.0
WH2_k127_10034690_2 Luciferase-like monooxygenase K04091 - 1.14.14.5 1.289e-220 703.0
WH2_k127_10034690_20 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000003859 217.0
WH2_k127_10034690_21 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000002177 216.0
WH2_k127_10034690_22 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000176 219.0
WH2_k127_10034690_23 FMN reductase K00299 - 1.5.1.38 0.00000000000000000000000000000000000000000000000000000000351 207.0
WH2_k127_10034690_24 Plasmid stabilization - - - 0.000000000000000000000000000000000000000005173 164.0
WH2_k127_10034690_25 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000004198 80.0
WH2_k127_10034690_27 PFAM ABC transporter K01995 - - 0.000000009546 57.0
WH2_k127_10034690_3 Belongs to the UPF0061 (SELO) family K08997 - - 4.41e-211 670.0
WH2_k127_10034690_4 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 531.0
WH2_k127_10034690_5 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 542.0
WH2_k127_10034690_6 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 487.0
WH2_k127_10034690_7 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 479.0
WH2_k127_10034690_8 AMP-binding enzyme C-terminal domain K01897,K16876 - 6.2.1.3,6.2.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 447.0
WH2_k127_10034690_9 citrate synthase K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 403.0
WH2_k127_10047855_0 Deoxyribodipyrimidine photo-lyase-related protein K06876 GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 1.485e-225 711.0
WH2_k127_10047855_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 1.362e-206 654.0
WH2_k127_10047855_10 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000000000018 143.0
WH2_k127_10047855_11 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000001644 126.0
WH2_k127_10047855_12 Uncharacterized protein conserved in bacteria (DUF2256) - - - 0.000000000000000000848 91.0
WH2_k127_10047855_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 592.0
WH2_k127_10047855_3 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 434.0
WH2_k127_10047855_4 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 379.0
WH2_k127_10047855_5 DNA-directed RNA polymerase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 339.0
WH2_k127_10047855_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 304.0
WH2_k127_10047855_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 305.0
WH2_k127_10047855_8 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003647 287.0
WH2_k127_10047855_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006838 278.0
WH2_k127_10096095_0 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.0 1298.0
WH2_k127_10096095_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 4.256e-195 614.0
WH2_k127_10096095_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 515.0
WH2_k127_10096095_3 NmrA-like family K19267 - 1.6.5.2 0.00000000000000000000000000000000000000000000000001145 190.0
WH2_k127_10096095_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000118 128.0
WH2_k127_10096095_5 COG1012 NAD-dependent aldehyde dehydrogenases K00140 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896 1.2.1.18,1.2.1.27 0.000000000000000000000003424 105.0
WH2_k127_10096095_6 - - - - 0.00000000000000005566 87.0
WH2_k127_10102783_0 glycosyl transferase family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 612.0
WH2_k127_10102783_1 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002358 284.0
WH2_k127_10102783_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
WH2_k127_10102783_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001582 263.0
WH2_k127_10102783_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004661 240.0
WH2_k127_10106525_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 572.0
WH2_k127_10106525_1 Belongs to the 5'-nucleotidase family K01081,K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 487.0
WH2_k127_10106525_10 Sel1-like repeats. - - - 0.0002089 49.0
WH2_k127_10106525_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 430.0
WH2_k127_10106525_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 355.0
WH2_k127_10106525_4 Molecular chaperone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 318.0
WH2_k127_10106525_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004284 280.0
WH2_k127_10106525_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000007604 193.0
WH2_k127_10106525_7 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000003267 167.0
WH2_k127_10106525_8 xylan catabolic process K03932 - - 0.0000000000000000000000000000000000004085 153.0
WH2_k127_10106525_9 Catalase K03781 - 1.11.1.6 0.000000000000000001956 87.0
WH2_k127_10152910_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.202e-228 711.0
WH2_k127_10152910_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 491.0
WH2_k127_10152910_10 PFAM Acetoacetate decarboxylase (ADC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006332 239.0
WH2_k127_10152910_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000002094 235.0
WH2_k127_10152910_12 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000004248 235.0
WH2_k127_10152910_13 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000001279 171.0
WH2_k127_10152910_14 Chorismate mutase K04092 - 5.4.99.5 0.000000000000000000000000000000000000003399 149.0
WH2_k127_10152910_15 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000001505 150.0
WH2_k127_10152910_16 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000002518 151.0
WH2_k127_10152910_17 periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000006158 143.0
WH2_k127_10152910_18 Usg-like family - - - 0.00000000000000000000000000000004419 127.0
WH2_k127_10152910_19 Protein of unknown function (DUF805) - - - 0.000000000000000000000000000001473 124.0
WH2_k127_10152910_2 COG2200 FOG EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 496.0
WH2_k127_10152910_20 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000001564 130.0
WH2_k127_10152910_21 Sterol carrier protein - - - 0.000000000000000000000009563 104.0
WH2_k127_10152910_22 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000002473 100.0
WH2_k127_10152910_23 Cysteine rich repeat - - - 0.0000000004851 63.0
WH2_k127_10152910_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 437.0
WH2_k127_10152910_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 383.0
WH2_k127_10152910_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 344.0
WH2_k127_10152910_6 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 331.0
WH2_k127_10152910_7 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 307.0
WH2_k127_10152910_8 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003203 255.0
WH2_k127_10152910_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000002287 250.0
WH2_k127_10188813_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 385.0
WH2_k127_10188813_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 362.0
WH2_k127_10188813_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003053 287.0
WH2_k127_10188813_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000009252 243.0
WH2_k127_10188813_4 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000000000000000003321 198.0
WH2_k127_10188813_5 electron transfer activity - - - 0.0000000000000001988 83.0
WH2_k127_10188813_6 Protein of unknown function (DUF3299) K09950 - - 0.00000008807 61.0
WH2_k127_10206596_0 ABC transporter, ATP-binding protein K06022,K10834 - 3.6.3.29,3.6.3.41 2.444e-303 935.0
WH2_k127_10206596_1 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 544.0
WH2_k127_10206596_10 nuclease activity K07062 - - 0.00000000000000000000000000000000000001218 149.0
WH2_k127_10206596_11 Cupin 4 family protein - - - 0.00000000000000000000000000000000001529 147.0
WH2_k127_10206596_12 Protein conserved in bacteria - - - 0.000000000000000000000000000006914 127.0
WH2_k127_10206596_13 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000611 119.0
WH2_k127_10206596_15 Resolvase, N terminal domain - - - 0.00000000000001603 76.0
WH2_k127_10206596_17 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000001549 63.0
WH2_k127_10206596_19 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000122 50.0
WH2_k127_10206596_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 484.0
WH2_k127_10206596_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 433.0
WH2_k127_10206596_4 restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 376.0
WH2_k127_10206596_5 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 377.0
WH2_k127_10206596_6 DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 361.0
WH2_k127_10206596_7 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 284.0
WH2_k127_10206596_8 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000000000000000000000000000000002372 228.0
WH2_k127_10206596_9 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000004435 199.0
WH2_k127_10225354_0 flagellum-specific ATP synthase K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 593.0
WH2_k127_10225354_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 453.0
WH2_k127_10225354_10 - K09712,K14475 - - 0.00000000000000002605 90.0
WH2_k127_10225354_11 Transcriptional regulator PadR-like family - - - 0.00000000000001256 75.0
WH2_k127_10225354_12 - - - - 0.00000001519 64.0
WH2_k127_10225354_13 - - - - 0.00000002154 63.0
WH2_k127_10225354_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 415.0
WH2_k127_10225354_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 362.0
WH2_k127_10225354_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 349.0
WH2_k127_10225354_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001203 245.0
WH2_k127_10225354_6 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11747 - - 0.0000000000000000000000000000000000000000000000000000000000009793 213.0
WH2_k127_10225354_7 Chemotaxis phosphatase, CheZ - - - 0.0000000000000000000000000000000000000000000000000001911 193.0
WH2_k127_10225354_8 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000001261 181.0
WH2_k127_10225354_9 cheY-homologous receiver domain - - - 0.000000000000000000000000000000009702 140.0
WH2_k127_10240646_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1462.0
WH2_k127_10240646_1 Class II Aldolase and Adducin N-terminal domain - - - 1.106e-292 922.0
WH2_k127_10240646_10 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 507.0
WH2_k127_10240646_11 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 494.0
WH2_k127_10240646_12 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 494.0
WH2_k127_10240646_13 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 444.0
WH2_k127_10240646_14 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 458.0
WH2_k127_10240646_15 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 443.0
WH2_k127_10240646_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 438.0
WH2_k127_10240646_17 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
WH2_k127_10240646_18 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 402.0
WH2_k127_10240646_19 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 359.0
WH2_k127_10240646_2 Cytochrome C and Quinol oxidase polypeptide I K00404 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 2.98e-258 802.0
WH2_k127_10240646_20 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 356.0
WH2_k127_10240646_21 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 344.0
WH2_k127_10240646_22 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 342.0
WH2_k127_10240646_23 Nitrile hydratase, alpha chain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 329.0
WH2_k127_10240646_24 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003151 286.0
WH2_k127_10240646_25 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007609 290.0
WH2_k127_10240646_26 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000675 280.0
WH2_k127_10240646_27 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003092 263.0
WH2_k127_10240646_28 Transition state regulatory protein AbrB K07120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001164 267.0
WH2_k127_10240646_29 Enoyl-CoA hydratase/isomerase K15313 - - 0.000000000000000000000000000000000000000000000000000000000000000000002672 250.0
WH2_k127_10240646_3 COG2217 Cation transport ATPase K01533 - 3.6.3.4 6.381e-253 808.0
WH2_k127_10240646_30 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001516 247.0
WH2_k127_10240646_31 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.000000000000000000000000000000000000000000000000000000000000000678 235.0
WH2_k127_10240646_32 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000002239 198.0
WH2_k127_10240646_33 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000005596 198.0
WH2_k127_10240646_34 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000003339 194.0
WH2_k127_10240646_35 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000001277 175.0
WH2_k127_10240646_36 COG1846 Transcriptional regulators - - - 0.00000000000000000000000000000000000001407 151.0
WH2_k127_10240646_37 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000001951 140.0
WH2_k127_10240646_38 O-Methyltransferase - - - 0.000000000000000000000001055 116.0
WH2_k127_10240646_39 Nitrile hydratase beta subunit - - - 0.000000000000000000000001154 112.0
WH2_k127_10240646_4 acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 2.966e-200 659.0
WH2_k127_10240646_40 FixH - - - 0.00000000000000000001896 99.0
WH2_k127_10240646_41 cytochrome oxidase maturation protein - - - 0.000000000000001145 78.0
WH2_k127_10240646_42 Cbb3-type cytochrome oxidase K00407 - - 0.00001749 48.0
WH2_k127_10240646_5 response regulator K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 617.0
WH2_k127_10240646_6 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009922 560.0
WH2_k127_10240646_7 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 556.0
WH2_k127_10240646_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 524.0
WH2_k127_10240646_9 IG-like fold at C-terminal of FixG, putative oxidoreductase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 528.0
WH2_k127_10260688_0 Periplasmic binding protein domain K11959 - - 2.499e-241 749.0
WH2_k127_10260688_1 Belongs to the catalase family K03781 - 1.11.1.6 2.979e-222 700.0
WH2_k127_10260688_2 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 582.0
WH2_k127_10260688_3 metalloendopeptidase activity K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 409.0
WH2_k127_10260688_4 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003724 243.0
WH2_k127_10260688_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000004163 207.0
WH2_k127_10260688_6 Protein of unknown function (DUF1674) - - - 0.0000001519 55.0
WH2_k127_10280095_0 Peptide ABC transporter permease K02033 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 475.0
WH2_k127_10280095_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 432.0
WH2_k127_10280095_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 405.0
WH2_k127_10280095_3 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 372.0
WH2_k127_10280095_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 381.0
WH2_k127_10280095_5 Belongs to the ABC transporter superfamily K02031,K02032 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 355.0
WH2_k127_10280095_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000009037 239.0
WH2_k127_10280095_7 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000000003196 214.0
WH2_k127_10280095_8 Transcriptional - - - 0.000000000000000000000000000000000000002156 149.0
WH2_k127_10320226_0 Arylsulfatase - - - 1.132e-247 792.0
WH2_k127_10320226_1 Belongs to the GcvT family K00302 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 580.0
WH2_k127_10320226_10 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009688 263.0
WH2_k127_10320226_11 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.000000000000000948 89.0
WH2_k127_10320226_12 Uncharacterized protein conserved in bacteria (DUF2076) K09945 - - 0.00000000005502 68.0
WH2_k127_10320226_13 Helix-turn-helix XRE-family like proteins - - - 0.000006298 53.0
WH2_k127_10320226_2 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 480.0
WH2_k127_10320226_3 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 475.0
WH2_k127_10320226_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 454.0
WH2_k127_10320226_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 443.0
WH2_k127_10320226_6 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 351.0
WH2_k127_10320226_7 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 347.0
WH2_k127_10320226_8 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 304.0
WH2_k127_10320226_9 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007595 275.0
WH2_k127_10328037_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 447.0
WH2_k127_10328037_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 431.0
WH2_k127_10328037_2 chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000001067 221.0
WH2_k127_10328037_3 ORF located using - - - 0.0000000000000000000000000000000003521 138.0
WH2_k127_10341590_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.543e-232 727.0
WH2_k127_10341590_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001739 262.0
WH2_k127_10341590_2 serine-type endopeptidase activity K01312 - 3.4.21.4 0.00000000000000000000000000000000000000006833 170.0
WH2_k127_10341590_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000003974 73.0
WH2_k127_1035489_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1168.0
WH2_k127_1035489_1 Catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway K18456 - 3.5.4.32 1.235e-234 735.0
WH2_k127_1035489_10 PFAM DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000135 215.0
WH2_k127_1035489_11 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000672 211.0
WH2_k127_1035489_12 Maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000002573 177.0
WH2_k127_1035489_13 Nucleotidyltransferase K09962 - - 0.0000000000000000000000000000000000000000000000004519 185.0
WH2_k127_1035489_14 - - - - 0.000000000000000000005851 110.0
WH2_k127_1035489_15 Lipid A 3-O-deacylase (PagL) - - - 0.0000000006251 62.0
WH2_k127_1035489_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.156e-198 635.0
WH2_k127_1035489_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 591.0
WH2_k127_1035489_4 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 465.0
WH2_k127_1035489_5 Zn-dependent protease, contains TPR repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 375.0
WH2_k127_1035489_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 400.0
WH2_k127_1035489_7 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001489 299.0
WH2_k127_1035489_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007696 271.0
WH2_k127_1035489_9 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000003201 229.0
WH2_k127_10362342_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.598e-232 751.0
WH2_k127_10362342_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 368.0
WH2_k127_10362342_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 338.0
WH2_k127_10362342_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 317.0
WH2_k127_10362342_4 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006009 243.0
WH2_k127_10362342_5 protein conserved in bacteria K09921 - - 0.00000000000000000000000000000000000000000000000000000003426 205.0
WH2_k127_10362342_6 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000237 205.0
WH2_k127_10362342_7 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000001564 189.0
WH2_k127_10362342_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000001007 159.0
WH2_k127_10362342_9 Acetyltransferase (GNAT) domain - - - 0.0001088 51.0
WH2_k127_10390140_0 AcrB/AcrD/AcrF family - - - 0.0 1292.0
WH2_k127_10390140_1 PFAM Protein kinase domain K01768,K07216 - 4.6.1.1 3.501e-300 981.0
WH2_k127_10390140_10 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000002807 230.0
WH2_k127_10390140_11 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000007105 215.0
WH2_k127_10390140_12 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' - - - 0.000000000000000000000000000000000000000000000001177 189.0
WH2_k127_10390140_13 Small multidrug resistance protein K11741 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000003007 169.0
WH2_k127_10390140_14 TonB C terminal K03832 - - 0.0000000000000000000000000006391 116.0
WH2_k127_10390140_15 Cro/C1-type HTH DNA-binding domain - - - 0.00000008868 62.0
WH2_k127_10390140_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 518.0
WH2_k127_10390140_3 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 490.0
WH2_k127_10390140_4 photoreceptor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 473.0
WH2_k127_10390140_5 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 473.0
WH2_k127_10390140_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 317.0
WH2_k127_10390140_7 A-factor biosynthesis hotdog domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005443 254.0
WH2_k127_10390140_8 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000878 254.0
WH2_k127_10390140_9 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002771 248.0
WH2_k127_10542993_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 426.0
WH2_k127_10542993_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 432.0
WH2_k127_10542993_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 313.0
WH2_k127_10542993_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001904 242.0
WH2_k127_10542993_4 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000004236 115.0
WH2_k127_10544204_0 AAA domain - - - 0.0 1124.0
WH2_k127_10544204_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.505e-295 936.0
WH2_k127_10544204_10 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000002129 263.0
WH2_k127_10544204_11 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000004466 234.0
WH2_k127_10544204_12 - - - - 0.000000000000000000000000000000000000000000000000000000000008696 228.0
WH2_k127_10544204_13 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000009092 220.0
WH2_k127_10544204_14 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000007728 195.0
WH2_k127_10544204_15 transcriptional regulator K13643 - - 0.000000000000000000000000000000000001161 143.0
WH2_k127_10544204_16 MaoC like domain K17865 GO:0003674,GO:0003824,GO:0003859,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016043,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0022607,GO:0032787,GO:0042620,GO:0042621,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0046487,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901576 4.2.1.55 0.000000000000000000000000000000000001234 145.0
WH2_k127_10544204_17 Polymer-forming cytoskeletal - - - 0.000000000000000000000000002341 116.0
WH2_k127_10544204_18 WHG domain - - - 0.00000000000004961 79.0
WH2_k127_10544204_19 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00001983 49.0
WH2_k127_10544204_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 614.0
WH2_k127_10544204_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 476.0
WH2_k127_10544204_4 Protein of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 485.0
WH2_k127_10544204_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 429.0
WH2_k127_10544204_6 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 425.0
WH2_k127_10544204_7 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 334.0
WH2_k127_10544204_8 belongs to the nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 334.0
WH2_k127_10544204_9 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001374 279.0
WH2_k127_10547372_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 4.018e-209 660.0
WH2_k127_10547372_1 COG2030 Acyl dehydratase K14449 - 4.2.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 501.0
WH2_k127_10547372_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 396.0
WH2_k127_10547372_3 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 367.0
WH2_k127_10547372_4 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005732 274.0
WH2_k127_10547372_5 adenylate kinase activity K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000464 179.0
WH2_k127_10547372_6 LysR substrate binding domain K03566 - - 0.00000000000000000000000000008366 118.0
WH2_k127_10552124_0 Flavin containing amine oxidoreductase K00466 - 1.13.12.3 2.522e-262 824.0
WH2_k127_10552124_1 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 624.0
WH2_k127_10552124_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000932 616.0
WH2_k127_10552124_3 methyl-accepting chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 579.0
WH2_k127_10552124_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009055 330.0
WH2_k127_10552124_5 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 306.0
WH2_k127_10552124_6 chemotaxis K03406 - - 0.00000000000000000000000000000000000000000000000000004452 206.0
WH2_k127_10552124_7 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000004758 177.0
WH2_k127_10552124_8 Metal dependent phosphohydrolases with conserved 'HD' motif. K06952 - - 0.00000000000000000000000004013 119.0
WH2_k127_10552124_9 HflC and HflK could regulate a protease K04087 - - 0.0000000003071 61.0
WH2_k127_10572669_0 TonB dependent receptor K02014 - - 8.206e-223 708.0
WH2_k127_10572669_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 614.0
WH2_k127_10572669_2 Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 498.0
WH2_k127_10572669_3 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000329 213.0
WH2_k127_10572669_4 - - - - 0.00000000000000000000000000004311 128.0
WH2_k127_10572669_5 Protein of unknown function (DUF3426) - - - 0.0000000000000000004725 93.0
WH2_k127_1060297_0 Molecular chaperone. Has ATPase activity K04079 - - 4.713e-255 808.0
WH2_k127_1060297_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.271e-220 698.0
WH2_k127_1060297_10 YbaK prolyl-tRNA synthetase associated region - - - 0.0000000003321 64.0
WH2_k127_1060297_2 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 591.0
WH2_k127_1060297_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 324.0
WH2_k127_1060297_4 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 314.0
WH2_k127_1060297_5 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000002284 199.0
WH2_k127_1060297_6 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000002596 183.0
WH2_k127_1060297_7 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000001493 185.0
WH2_k127_1060297_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000608 158.0
WH2_k127_1060297_9 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000009232 113.0
WH2_k127_10653988_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.978e-215 679.0
WH2_k127_10653988_1 PFAM Substrate-binding region of ABC-type glycine betaine transport system K05845 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 451.0
WH2_k127_10653988_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000003824 94.0
WH2_k127_10653988_11 Aminotransferase class I and II - - - 0.000006373 49.0
WH2_k127_10653988_2 ABC transporter K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 454.0
WH2_k127_10653988_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 434.0
WH2_k127_10653988_4 ABC-type proline glycine betaine transport systems, permease component K05846 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 426.0
WH2_k127_10653988_5 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 404.0
WH2_k127_10653988_6 ATPases associated with a variety of cellular activities K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 376.0
WH2_k127_10653988_7 PFAM binding-protein-dependent transport systems inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 331.0
WH2_k127_10653988_8 Transcriptional regulatory protein, C terminal K14981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 302.0
WH2_k127_10653988_9 Histidine kinase-like ATPases K14980 - 2.7.13.3 0.0000000000000000000006186 104.0
WH2_k127_10681358_0 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 383.0
WH2_k127_10681358_1 flagellar basal-body rod protein FlgG K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 331.0
WH2_k127_10681358_10 Class II flagellar assembly regulator - - - 0.0000000000000000001984 94.0
WH2_k127_10681358_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 323.0
WH2_k127_10681358_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005833 277.0
WH2_k127_10681358_4 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000003346 217.0
WH2_k127_10681358_5 Helix-turn-helix domain, rpiR family - - - 0.00000000000000000000000000000000000000000000000000000000006789 207.0
WH2_k127_10681358_6 Belongs to the flagella basal body rod proteins family K02391 - - 0.0000000000000000000000000000000000000000000000000000000005981 212.0
WH2_k127_10681358_7 Flagellar basal body P-ring biosynthesis protein K02386 - - 0.0000000000000000000000000000000000000005584 162.0
WH2_k127_10681358_8 - - - - 0.0000000000000000000000000000000199 130.0
WH2_k127_10681358_9 - - - - 0.0000000000000000000000006401 117.0
WH2_k127_10784698_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 7.92e-283 879.0
WH2_k127_10784698_1 belongs to the aldehyde dehydrogenase family - - - 1.074e-203 653.0
WH2_k127_10784698_10 PFAM glycoside hydrolase family 3 domain protein K01207,K05349 - 3.2.1.21,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 375.0
WH2_k127_10784698_11 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 323.0
WH2_k127_10784698_12 Bacterial periplasmic substrate-binding proteins K01713 - 4.2.1.51,4.2.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 312.0
WH2_k127_10784698_13 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 303.0
WH2_k127_10784698_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006639 278.0
WH2_k127_10784698_15 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001361 249.0
WH2_k127_10784698_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000001267 251.0
WH2_k127_10784698_17 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000553 230.0
WH2_k127_10784698_18 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000108 236.0
WH2_k127_10784698_19 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000004774 228.0
WH2_k127_10784698_2 COG2873 O-acetylhomoserine sulfhydrylase K01738,K01740 - 2.5.1.47,2.5.1.49 4.083e-201 642.0
WH2_k127_10784698_20 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000003099 209.0
WH2_k127_10784698_21 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000002844 175.0
WH2_k127_10784698_22 Metallo-peptidase family M12B Reprolysin-like - - - 0.0000000000000000000000000000000000000000008312 178.0
WH2_k127_10784698_23 Sporulation related domain - - - 0.0000000000000000004558 89.0
WH2_k127_10784698_24 ferric iron reductase K13255 - - 0.00000005166 65.0
WH2_k127_10784698_25 Protein of unknown function (DUF2845) - - - 0.000002522 55.0
WH2_k127_10784698_26 OmpA family - - - 0.00002632 53.0
WH2_k127_10784698_3 Aminotransferase class-III K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 589.0
WH2_k127_10784698_4 Belongs to the amidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 561.0
WH2_k127_10784698_5 ABC-type dipeptide transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 563.0
WH2_k127_10784698_6 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 529.0
WH2_k127_10784698_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 497.0
WH2_k127_10784698_8 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 396.0
WH2_k127_10784698_9 depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 377.0
WH2_k127_10790731_0 Pyridine nucleotide-disulphide oxidoreductase K00362,K18359 - 1.2.1.58,1.7.1.15 0.0 1447.0
WH2_k127_10790731_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1237.0
WH2_k127_10790731_2 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000587 224.0
WH2_k127_10790731_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000001747 217.0
WH2_k127_10790731_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000002196 220.0
WH2_k127_10790731_5 Sugar-specific transcriptional regulator TrmB K03892 - - 0.000000000000000000000000000000000000000000000000000103 187.0
WH2_k127_10790731_6 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.0000000000000000000000000000000000000000000003305 180.0
WH2_k127_10790731_7 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000001903 168.0
WH2_k127_1116543_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 425.0
WH2_k127_1116543_1 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 375.0
WH2_k127_1116543_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 359.0
WH2_k127_1116543_3 HemY protein N-terminus K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002716 297.0
WH2_k127_1116543_4 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000003561 197.0
WH2_k127_1116543_5 COG1587 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000001513 186.0
WH2_k127_1116543_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000001157 186.0
WH2_k127_1116543_7 Mitochondrial inner membrane protein - - - 0.000000000000000000000003338 116.0
WH2_k127_1116543_8 - - - - 0.000000000000000000001049 94.0
WH2_k127_1116543_9 - - - - 0.00000000003453 64.0
WH2_k127_1262891_0 Biotin carboxylase - - - 0.0 1231.0
WH2_k127_1262891_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.313e-214 672.0
WH2_k127_1262891_10 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000004522 119.0
WH2_k127_1262891_11 Thioesterase-like superfamily K07107 - - 0.0000002338 61.0
WH2_k127_1262891_2 AMP-binding enzyme K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 577.0
WH2_k127_1262891_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 497.0
WH2_k127_1262891_4 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 445.0
WH2_k127_1262891_5 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 329.0
WH2_k127_1262891_6 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 317.0
WH2_k127_1262891_7 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 295.0
WH2_k127_1262891_8 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001586 302.0
WH2_k127_1262891_9 ATPases associated with a variety of cellular activities K01996 GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008144,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:0098655,GO:0098656,GO:1901265,GO:1901363,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000001064 248.0
WH2_k127_1302160_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.656e-269 851.0
WH2_k127_1302160_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.76e-198 639.0
WH2_k127_1302160_10 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000238 88.0
WH2_k127_1302160_2 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 479.0
WH2_k127_1302160_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 438.0
WH2_k127_1302160_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 342.0
WH2_k127_1302160_5 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 310.0
WH2_k127_1302160_6 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 275.0
WH2_k127_1302160_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007928 265.0
WH2_k127_1302160_8 FCD - - - 0.0000000000000000000000000000000000000000000000000000004904 202.0
WH2_k127_1302160_9 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000002612 193.0
WH2_k127_1325782_0 Aminotransferase class I and II K00813,K00832 - 2.6.1.1,2.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 531.0
WH2_k127_1325782_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 504.0
WH2_k127_1325782_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000008543 143.0
WH2_k127_1325782_11 PRC-barrel domain - - - 0.00000000000000004156 85.0
WH2_k127_1325782_12 Domain of unknown function (DUF4142) - - - 0.00000000000000008414 90.0
WH2_k127_1325782_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 451.0
WH2_k127_1325782_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 428.0
WH2_k127_1325782_4 DNA topoisomerase K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 353.0
WH2_k127_1325782_5 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000034 220.0
WH2_k127_1325782_6 PRC-barrel domain - - - 0.00000000000000000000000000000000000000000000000000004838 190.0
WH2_k127_1325782_7 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000006158 186.0
WH2_k127_1325782_8 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000001854 173.0
WH2_k127_1325782_9 Protein of unknown function (DUF2000) - - - 0.00000000000000000000000000000000000000000002547 167.0
WH2_k127_1327851_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 9.111e-285 889.0
WH2_k127_1327851_1 Poly-beta-hydroxybutyrate polymerase K03821 - - 2.332e-281 874.0
WH2_k127_1327851_10 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 432.0
WH2_k127_1327851_11 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 404.0
WH2_k127_1327851_12 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 411.0
WH2_k127_1327851_13 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 401.0
WH2_k127_1327851_14 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 387.0
WH2_k127_1327851_15 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 389.0
WH2_k127_1327851_16 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 374.0
WH2_k127_1327851_17 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 381.0
WH2_k127_1327851_18 TOBE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 376.0
WH2_k127_1327851_19 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 351.0
WH2_k127_1327851_2 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 - 3.5.2.14 1.282e-261 831.0
WH2_k127_1327851_20 Belongs to the amidase family K21801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 340.0
WH2_k127_1327851_21 FAD dependent oxidoreductase K04755,K09471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 332.0
WH2_k127_1327851_22 amino acid K01996,K11958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 321.0
WH2_k127_1327851_23 Binding-protein-dependent transport system inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 329.0
WH2_k127_1327851_24 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 308.0
WH2_k127_1327851_25 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 321.0
WH2_k127_1327851_26 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 306.0
WH2_k127_1327851_27 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 294.0
WH2_k127_1327851_28 binding-protein-dependent transport systems inner membrane component K02050,K15554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001438 286.0
WH2_k127_1327851_29 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009723 297.0
WH2_k127_1327851_3 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 1.964e-250 787.0
WH2_k127_1327851_30 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003164 279.0
WH2_k127_1327851_31 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004714 293.0
WH2_k127_1327851_32 LysR substrate binding domain K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000252 278.0
WH2_k127_1327851_33 Beta-lactamase K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000001762 274.0
WH2_k127_1327851_34 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006448 249.0
WH2_k127_1327851_35 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000005985 238.0
WH2_k127_1327851_36 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.0000000000000000000000000000000000000000000000000000001541 214.0
WH2_k127_1327851_37 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000009092 188.0
WH2_k127_1327851_38 - - - - 0.0000000000000000000000000000000000000000000000000009397 190.0
WH2_k127_1327851_39 Regulatory protein MarR - - - 0.00000000000000000000000000000000000000000000000001305 185.0
WH2_k127_1327851_4 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 605.0
WH2_k127_1327851_40 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000002382 192.0
WH2_k127_1327851_41 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000005994 178.0
WH2_k127_1327851_42 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000001651 155.0
WH2_k127_1327851_43 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000001606 85.0
WH2_k127_1327851_44 cytochrome C - - - 0.0000000000003288 76.0
WH2_k127_1327851_5 FAD binding domain K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 546.0
WH2_k127_1327851_6 Putative serine dehydratase domain K01753 - 4.3.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 505.0
WH2_k127_1327851_7 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008256 513.0
WH2_k127_1327851_8 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000737 480.0
WH2_k127_1327851_9 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 484.0
WH2_k127_1329083_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.252e-246 772.0
WH2_k127_1329083_1 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 372.0
WH2_k127_1329083_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000007523 166.0
WH2_k127_1329083_3 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000000000000009554 142.0
WH2_k127_1329083_4 Sporulation related domain - - - 0.00000000000000002105 89.0
WH2_k127_1329083_6 - - - - 0.0002396 53.0
WH2_k127_1347526_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812,K08351 - 1.7.2.3 0.0 1011.0
WH2_k127_1347526_1 Uncharacterized protein conserved in bacteria (DUF2090) K03338 - 2.7.1.92 3.516e-280 874.0
WH2_k127_1347526_10 PFAM response regulator receiver - - - 8.821e-204 669.0
WH2_k127_1347526_11 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 1.21e-200 634.0
WH2_k127_1347526_12 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 4.173e-198 645.0
WH2_k127_1347526_13 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 622.0
WH2_k127_1347526_14 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 586.0
WH2_k127_1347526_15 Biotin carboxylase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 549.0
WH2_k127_1347526_16 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 527.0
WH2_k127_1347526_17 aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 508.0
WH2_k127_1347526_18 Extracellular solute-binding protein K02012,K11081 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 485.0
WH2_k127_1347526_19 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 491.0
WH2_k127_1347526_2 Belongs to the TPP enzyme family K03336 - 3.7.1.22 4.415e-275 857.0
WH2_k127_1347526_20 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 452.0
WH2_k127_1347526_21 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 425.0
WH2_k127_1347526_22 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 414.0
WH2_k127_1347526_23 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 418.0
WH2_k127_1347526_24 ABC transporter K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 418.0
WH2_k127_1347526_25 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 402.0
WH2_k127_1347526_26 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 394.0
WH2_k127_1347526_27 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 389.0
WH2_k127_1347526_28 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 359.0
WH2_k127_1347526_29 5-deoxyglucuronate isomerase K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 369.0
WH2_k127_1347526_3 Binding-protein-dependent transport system inner membrane component K02011 - - 7.032e-267 848.0
WH2_k127_1347526_30 TRAP transporter, solute receptor (TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 365.0
WH2_k127_1347526_31 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 344.0
WH2_k127_1347526_32 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 319.0
WH2_k127_1347526_33 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 321.0
WH2_k127_1347526_34 Helix-turn-helix domain, rpiR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 312.0
WH2_k127_1347526_35 PFAM regulatory protein TetR K13770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004804 267.0
WH2_k127_1347526_36 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001377 254.0
WH2_k127_1347526_37 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000006831 259.0
WH2_k127_1347526_38 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000002058 242.0
WH2_k127_1347526_39 Inositol monophosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000003522 220.0
WH2_k127_1347526_4 Carboxyl transferase domain K01969 - 6.4.1.4 1.359e-264 831.0
WH2_k127_1347526_40 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000004068 154.0
WH2_k127_1347526_41 PFAM CheW domain protein K03408 - - 0.000000000000000000000003929 108.0
WH2_k127_1347526_42 - - - - 0.0000000000000000002128 101.0
WH2_k127_1347526_43 Biotin-requiring enzyme - - - 0.00000000000001856 84.0
WH2_k127_1347526_44 PBP superfamily domain K02040 - - 0.00000002012 59.0
WH2_k127_1347526_5 CoA binding domain - - - 1.614e-234 745.0
WH2_k127_1347526_6 Extracellular solute-binding protein, family 5 K02035 - - 9.623e-232 728.0
WH2_k127_1347526_7 ATP-binding region ATPase domain protein K03407,K13490 - 2.7.13.3 6.861e-226 720.0
WH2_k127_1347526_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.578e-205 644.0
WH2_k127_1347526_9 PFAM histidine kinase HAMP region domain protein K03406 - - 4.141e-204 649.0
WH2_k127_135704_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 572.0
WH2_k127_135704_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000004504 233.0
WH2_k127_135704_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000001215 203.0
WH2_k127_135704_3 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000004259 189.0
WH2_k127_135704_4 TIGRFAM protein TolA - - - 0.00000000000000000000000000000001447 134.0
WH2_k127_1369677_0 hydrolase of the metallo-beta-lactamase superfamily K12574 - - 3.021e-202 644.0
WH2_k127_1369677_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 591.0
WH2_k127_1369677_10 Protein of unknown function (DUF1467) - - - 0.00003632 53.0
WH2_k127_1369677_2 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 557.0
WH2_k127_1369677_3 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 398.0
WH2_k127_1369677_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 312.0
WH2_k127_1369677_5 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000002758 239.0
WH2_k127_1369677_6 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000005426 231.0
WH2_k127_1369677_7 - - - - 0.0000000000000000000000000000000000000000005075 175.0
WH2_k127_1369677_8 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000003531 141.0
WH2_k127_1369677_9 Phosphatase K19302 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0042221,GO:0044464,GO:0046677,GO:0050380,GO:0050896,GO:0071944 3.6.1.27 0.0000000000000000000004462 110.0
WH2_k127_137224_0 AMP-binding enzyme K12508 - 6.2.1.34 3.426e-216 689.0
WH2_k127_137224_1 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 615.0
WH2_k127_137224_10 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 296.0
WH2_k127_137224_11 Inositol monophosphatase family K01082 GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0008934,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019637,GO:0019693,GO:0030145,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050308,GO:0050427,GO:0050897,GO:0052745,GO:0052834,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 292.0
WH2_k127_137224_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 307.0
WH2_k127_137224_13 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001331 278.0
WH2_k127_137224_14 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001671 258.0
WH2_k127_137224_15 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000003963 220.0
WH2_k127_137224_16 - - - - 0.0000000000000000000000000000000000000000000000000001625 193.0
WH2_k127_137224_17 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000374 199.0
WH2_k127_137224_18 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.00000000000000000000000000006681 118.0
WH2_k127_137224_19 Protein of unknown function (DUF3553) - - - 0.00000000000000001839 83.0
WH2_k127_137224_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 558.0
WH2_k127_137224_20 peptidyl-tyrosine sulfation - - - 0.00000000000002747 78.0
WH2_k127_137224_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 467.0
WH2_k127_137224_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 421.0
WH2_k127_137224_5 alcohol dehydrogenase K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 383.0
WH2_k127_137224_6 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 386.0
WH2_k127_137224_7 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 361.0
WH2_k127_137224_8 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 341.0
WH2_k127_137224_9 (LPS) heptosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 323.0
WH2_k127_1398214_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.04e-322 1001.0
WH2_k127_1398214_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009708 491.0
WH2_k127_1398214_10 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 378.0
WH2_k127_1398214_11 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 363.0
WH2_k127_1398214_12 Transmembrane secretion effector K08217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 334.0
WH2_k127_1398214_13 COG4597 ABC-type amino acid transport system, permease component K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 329.0
WH2_k127_1398214_14 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 309.0
WH2_k127_1398214_15 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 305.0
WH2_k127_1398214_16 Phytanoyl-CoA dioxygenase (PhyH) K00477 - 1.14.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 292.0
WH2_k127_1398214_17 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002597 278.0
WH2_k127_1398214_18 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000003568 246.0
WH2_k127_1398214_19 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000009467 224.0
WH2_k127_1398214_2 Bacterial extracellular solute-binding protein K02055,K05777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 463.0
WH2_k127_1398214_20 ATPases associated with a variety of cellular activities K05779 - - 0.000000000000000000000000000000000000000000000000000000000005528 233.0
WH2_k127_1398214_21 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000001795 210.0
WH2_k127_1398214_22 Alpha beta - - - 0.0000000000000000000000000000000000000000000000000000005476 206.0
WH2_k127_1398214_23 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000005045 187.0
WH2_k127_1398214_24 transglycosylase - - - 0.00000000000000000000000000000000000000000000001968 186.0
WH2_k127_1398214_25 COG2867 Oligoketide cyclase lipid transport protein K18588 - - 0.0000000000000000000000000000000000000000001845 160.0
WH2_k127_1398214_26 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000001239 166.0
WH2_k127_1398214_27 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000008692 145.0
WH2_k127_1398214_28 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000000001461 143.0
WH2_k127_1398214_3 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 445.0
WH2_k127_1398214_4 transport system, permease component K05778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 453.0
WH2_k127_1398214_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 442.0
WH2_k127_1398214_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 403.0
WH2_k127_1398214_7 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 372.0
WH2_k127_1398214_8 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 377.0
WH2_k127_1398214_9 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 379.0
WH2_k127_1412546_0 PAS fold - - - 2.688e-267 843.0
WH2_k127_1412546_1 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 413.0
WH2_k127_1412546_2 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004327 278.0
WH2_k127_1412546_3 araC family K13652,K13653 - - 0.000000000000000000000000000000000000000000000000000000001622 202.0
WH2_k127_1412546_4 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000000000000000000000000000000000000002648 221.0
WH2_k127_1412546_5 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000001969 160.0
WH2_k127_1412546_6 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000003346 119.0
WH2_k127_1412546_7 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000147 117.0
WH2_k127_1412546_8 MAPEG family - - - 0.00000000000000000001422 105.0
WH2_k127_1412546_9 - - - - 0.0000000000000003516 92.0
WH2_k127_1455259_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1102.0
WH2_k127_1455259_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1054.0
WH2_k127_1455259_10 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000004906 171.0
WH2_k127_1455259_11 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.000000000000000000000000000000000000000000242 168.0
WH2_k127_1455259_12 protein deglycase activity - - - 0.000000000000000000246 94.0
WH2_k127_1455259_13 Pectate lyase superfamily protein - - - 0.0002548 53.0
WH2_k127_1455259_2 Alpha amylase, catalytic domain K06044 - 5.4.99.15 1.084e-304 962.0
WH2_k127_1455259_3 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 6.686e-273 844.0
WH2_k127_1455259_4 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 2.683e-241 760.0
WH2_k127_1455259_5 NB-ARC domain - - - 1.427e-233 756.0
WH2_k127_1455259_6 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.04e-212 683.0
WH2_k127_1455259_7 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 576.0
WH2_k127_1455259_8 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 469.0
WH2_k127_1455259_9 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 360.0
WH2_k127_1479013_0 Aldehyde oxidase and xanthine dehydrogenase - - - 1.72e-318 985.0
WH2_k127_1479013_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 8.14e-281 883.0
WH2_k127_1479013_10 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 333.0
WH2_k127_1479013_11 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 291.0
WH2_k127_1479013_12 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001513 280.0
WH2_k127_1479013_13 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003042 268.0
WH2_k127_1479013_14 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007605 263.0
WH2_k127_1479013_15 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003251 234.0
WH2_k127_1479013_16 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000008918 235.0
WH2_k127_1479013_17 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.0000000000000000000000000000000000000000000000000000000000002997 217.0
WH2_k127_1479013_18 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000005942 171.0
WH2_k127_1479013_19 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000005945 167.0
WH2_k127_1479013_2 Aldehyde dehydrogenase family K21802 - 1.2.1.67 8.099e-233 729.0
WH2_k127_1479013_20 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000009155 151.0
WH2_k127_1479013_21 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000001277 140.0
WH2_k127_1479013_22 SnoaL-like domain - - - 0.000000000000000000000000000001606 125.0
WH2_k127_1479013_23 luxR family - - - 0.00001662 55.0
WH2_k127_1479013_3 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.736e-215 675.0
WH2_k127_1479013_4 Histidine kinase K07677 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042710,GO:0043170,GO:0043412,GO:0044010,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051716,GO:0065007,GO:0071214,GO:0071470,GO:0071704,GO:0071944,GO:0104004,GO:0140096,GO:1901564 2.7.13.3 3.444e-198 659.0
WH2_k127_1479013_5 Kelch repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 508.0
WH2_k127_1479013_6 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 498.0
WH2_k127_1479013_7 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 440.0
WH2_k127_1479013_8 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 381.0
WH2_k127_1479013_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 371.0
WH2_k127_1512426_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1057.0
WH2_k127_1512426_1 Penicillin amidase K01434 - 3.5.1.11 8.977e-275 867.0
WH2_k127_1512426_10 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 507.0
WH2_k127_1512426_11 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 490.0
WH2_k127_1512426_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 470.0
WH2_k127_1512426_13 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 465.0
WH2_k127_1512426_14 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 466.0
WH2_k127_1512426_15 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 466.0
WH2_k127_1512426_16 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 454.0
WH2_k127_1512426_17 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 447.0
WH2_k127_1512426_18 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 441.0
WH2_k127_1512426_19 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 422.0
WH2_k127_1512426_2 COG1960 Acyl-CoA dehydrogenases K00252 - 1.3.8.6 3.468e-212 665.0
WH2_k127_1512426_20 mandelate racemase muconate lactonizing K19802 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 423.0
WH2_k127_1512426_21 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 409.0
WH2_k127_1512426_22 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 405.0
WH2_k127_1512426_23 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 404.0
WH2_k127_1512426_24 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 400.0
WH2_k127_1512426_25 ATPases associated with a variety of cellular activities K02028,K10004 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 404.0
WH2_k127_1512426_26 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 372.0
WH2_k127_1512426_27 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 372.0
WH2_k127_1512426_28 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 376.0
WH2_k127_1512426_29 Bacterial regulatory helix-turn-helix protein, lysR family K21645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 370.0
WH2_k127_1512426_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 6.143e-206 647.0
WH2_k127_1512426_30 Enoyl-CoA hydratase/isomerase K01692,K05605 - 3.1.2.4,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 381.0
WH2_k127_1512426_31 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 364.0
WH2_k127_1512426_32 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 359.0
WH2_k127_1512426_33 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 357.0
WH2_k127_1512426_34 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 325.0
WH2_k127_1512426_35 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 323.0
WH2_k127_1512426_36 PBP superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 303.0
WH2_k127_1512426_37 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 299.0
WH2_k127_1512426_38 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 304.0
WH2_k127_1512426_39 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 294.0
WH2_k127_1512426_4 COG1960 Acyl-CoA dehydrogenases - - - 4.032e-199 626.0
WH2_k127_1512426_40 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 286.0
WH2_k127_1512426_41 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001106 297.0
WH2_k127_1512426_42 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007624 283.0
WH2_k127_1512426_43 AraC-binding-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003747 290.0
WH2_k127_1512426_44 Riboflavin synthase alpha chain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001136 270.0
WH2_k127_1512426_45 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003973 248.0
WH2_k127_1512426_46 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000007856 243.0
WH2_k127_1512426_47 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000001291 220.0
WH2_k127_1512426_48 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000001236 216.0
WH2_k127_1512426_49 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000001321 221.0
WH2_k127_1512426_5 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 586.0
WH2_k127_1512426_50 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000001042 197.0
WH2_k127_1512426_51 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000002367 198.0
WH2_k127_1512426_52 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000000000000000000000000000000003841 188.0
WH2_k127_1512426_53 small integral membrane protein - - - 0.00000000000000000000000000000000000000000000000007862 181.0
WH2_k127_1512426_54 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000001359 182.0
WH2_k127_1512426_55 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000002941 154.0
WH2_k127_1512426_56 Ubiquinol-cytochrome C chaperone K17662 - - 0.00000000000000000000000000000000000000006027 158.0
WH2_k127_1512426_57 MerR family regulatory protein - - - 0.00000000000000000000000000000000000006654 148.0
WH2_k127_1512426_58 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000127 150.0
WH2_k127_1512426_59 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000001393 148.0
WH2_k127_1512426_6 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 580.0
WH2_k127_1512426_60 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000008732 136.0
WH2_k127_1512426_61 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000002426 141.0
WH2_k127_1512426_62 COG2913 Small protein A (tmRNA-binding) - - - 0.00000000000000000000000000001643 125.0
WH2_k127_1512426_63 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000001973 120.0
WH2_k127_1512426_64 Phage lysozyme K01185 - 3.2.1.17 0.00000000000000000000000000007566 126.0
WH2_k127_1512426_65 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000003436 124.0
WH2_k127_1512426_66 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000005989 120.0
WH2_k127_1512426_67 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000001421 106.0
WH2_k127_1512426_68 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000001048 122.0
WH2_k127_1512426_69 Thioesterase-like superfamily K07107 - - 0.000000000003651 72.0
WH2_k127_1512426_7 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 568.0
WH2_k127_1512426_70 - - - - 0.000000000009172 68.0
WH2_k127_1512426_71 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0000001765 63.0
WH2_k127_1512426_72 Major Facilitator Superfamily - - - 0.0000004439 56.0
WH2_k127_1512426_74 COG0477 Permeases of the major facilitator superfamily - - - 0.0002575 49.0
WH2_k127_1512426_8 PFAM Peptidase family M20 M25 M40 K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 514.0
WH2_k127_1512426_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 528.0
WH2_k127_15277_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 2.504e-260 827.0
WH2_k127_15277_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.992e-239 742.0
WH2_k127_15277_10 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 364.0
WH2_k127_15277_11 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 347.0
WH2_k127_15277_12 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 330.0
WH2_k127_15277_13 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 332.0
WH2_k127_15277_14 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 321.0
WH2_k127_15277_15 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 320.0
WH2_k127_15277_16 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 308.0
WH2_k127_15277_17 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 300.0
WH2_k127_15277_18 Domain of unknown function (DUF3883) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 303.0
WH2_k127_15277_19 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 289.0
WH2_k127_15277_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.249e-210 660.0
WH2_k127_15277_20 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001335 242.0
WH2_k127_15277_21 maltose O-acetyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000004903 226.0
WH2_k127_15277_22 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000009081 219.0
WH2_k127_15277_23 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000001156 224.0
WH2_k127_15277_24 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000001221 222.0
WH2_k127_15277_25 Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000000000000000000003233 216.0
WH2_k127_15277_26 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000003552 222.0
WH2_k127_15277_27 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000002522 210.0
WH2_k127_15277_28 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000009287 229.0
WH2_k127_15277_29 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000007673 209.0
WH2_k127_15277_3 LUD domain K18929 - - 4.301e-197 624.0
WH2_k127_15277_30 Protein of unknown function (DUF2889) - - - 0.0000000000000000000000000000000000000000000000000003288 189.0
WH2_k127_15277_31 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000007421 194.0
WH2_k127_15277_32 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.0000000000000000000000000000000000000000000000002212 187.0
WH2_k127_15277_33 Ferredoxin, 2Fe-2S - - - 0.000000000000000000000000000000000000000000000002487 179.0
WH2_k127_15277_34 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000000000000000000000000000000000000008325 171.0
WH2_k127_15277_35 Transcriptional - - - 0.00000000000000000000000000000000000000000004495 164.0
WH2_k127_15277_36 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000001379 171.0
WH2_k127_15277_37 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.00000000000000000000000000000000000003511 147.0
WH2_k127_15277_38 protein conserved in bacteria - - - 0.000000000000000000000000000003995 128.0
WH2_k127_15277_39 domain, Protein - - - 0.00000000000000000000000000002571 119.0
WH2_k127_15277_4 PFAM NAD-dependent epimerase dehydratase K01710,K01784,K02473,K08678 - 4.1.1.35,4.2.1.46,5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 532.0
WH2_k127_15277_40 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000004702 106.0
WH2_k127_15277_41 Protein of unknown function (DUF2628) - - - 0.00000000000000000002988 95.0
WH2_k127_15277_42 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000006864 63.0
WH2_k127_15277_43 Protein of unknown function (DUF3606) - - - 0.000001046 53.0
WH2_k127_15277_44 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00002705 47.0
WH2_k127_15277_5 membrane-bound lytic murein transglycosylase K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 469.0
WH2_k127_15277_6 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 462.0
WH2_k127_15277_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 446.0
WH2_k127_15277_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 418.0
WH2_k127_15277_9 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 395.0
WH2_k127_1616408_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0 1088.0
WH2_k127_1616408_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 4.725e-312 1000.0
WH2_k127_1616408_10 hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 347.0
WH2_k127_1616408_11 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 324.0
WH2_k127_1616408_12 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001149 257.0
WH2_k127_1616408_13 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000006932 243.0
WH2_k127_1616408_14 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000003364 235.0
WH2_k127_1616408_15 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000919 226.0
WH2_k127_1616408_16 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000001769 223.0
WH2_k127_1616408_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000004264 201.0
WH2_k127_1616408_18 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000006924 216.0
WH2_k127_1616408_19 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000002498 201.0
WH2_k127_1616408_2 Aldehyde oxidase and xanthine dehydrogenase - - - 7.8e-246 784.0
WH2_k127_1616408_20 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000002141 193.0
WH2_k127_1616408_21 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000006467 190.0
WH2_k127_1616408_22 - - - - 0.00000000000000000000000000000000000000000007836 166.0
WH2_k127_1616408_23 PFAM 2Fe-2S -binding K03518,K13483 - 1.2.5.3 0.00000000000000000000000000000000000934 152.0
WH2_k127_1616408_24 transcriptional K03710 - - 0.00000000000000000000000002212 119.0
WH2_k127_1616408_25 AraC-like ligand binding domain - - - 0.000000000000000000002128 103.0
WH2_k127_1616408_26 - - - - 0.0000000000000000003711 92.0
WH2_k127_1616408_27 PIN domain - - - 0.000000000000888 70.0
WH2_k127_1616408_28 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000003018 65.0
WH2_k127_1616408_3 Alcohol dehydrogenase GroES-associated - - - 7.033e-230 717.0
WH2_k127_1616408_30 Cro/C1-type HTH DNA-binding domain - - - 0.0003878 50.0
WH2_k127_1616408_4 ABC transporter - - - 2.049e-211 667.0
WH2_k127_1616408_5 ABC-type transport system, periplasmic component surface lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 495.0
WH2_k127_1616408_6 Manganese containing catalase K07217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 451.0
WH2_k127_1616408_7 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 452.0
WH2_k127_1616408_8 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 421.0
WH2_k127_1616408_9 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 358.0
WH2_k127_164013_0 NAD-specific glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1724.0
WH2_k127_164013_1 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 7.115e-244 765.0
WH2_k127_164013_10 ABC-type spermidine putrescine transport system, permease component II K11074 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 311.0
WH2_k127_164013_11 Protoglobin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001846 273.0
WH2_k127_164013_12 Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000001941 244.0
WH2_k127_164013_13 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000002872 237.0
WH2_k127_164013_14 Gram-negative porin K08720 - - 0.0000000000000000000000000000000000000000000000000000000000005921 228.0
WH2_k127_164013_15 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000002796 183.0
WH2_k127_164013_16 FCD - - - 0.00000000000000000000000000000000000000001404 162.0
WH2_k127_164013_17 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000615 110.0
WH2_k127_164013_18 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000001583 107.0
WH2_k127_164013_19 Zinc carboxypeptidase - - - 0.0000000000006812 72.0
WH2_k127_164013_2 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 7.922e-217 682.0
WH2_k127_164013_3 Bacterial extracellular solute-binding protein K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 443.0
WH2_k127_164013_4 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0019808,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 382.0
WH2_k127_164013_5 TOBE domain K11076 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 381.0
WH2_k127_164013_6 Binding-protein-dependent transport system inner membrane component K11075 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 370.0
WH2_k127_164013_7 Haem utilisation ChuX/HutX K07225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 370.0
WH2_k127_164013_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 316.0
WH2_k127_164013_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 311.0
WH2_k127_165015_0 Methionine synthase K00548 - 2.1.1.13 0.0 1688.0
WH2_k127_165015_1 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1253.0
WH2_k127_165015_10 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.000000000000000000000000000000000000000000000000000000000000000002765 243.0
WH2_k127_165015_11 Sodium Bile acid symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000003715 251.0
WH2_k127_165015_12 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000005617 199.0
WH2_k127_165015_13 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000114 183.0
WH2_k127_165015_14 COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.000000000000000000000000000000000000000000003831 175.0
WH2_k127_165015_15 Spermidine putrescine ABC transporter ATP-binding protein K02053 - - 0.0000000000000000000000000000000000000000001848 169.0
WH2_k127_165015_16 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000004548 155.0
WH2_k127_165015_17 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000001407 154.0
WH2_k127_165015_18 IclR family transcriptional regulator - - - 0.00000000000000000000000000000000005661 144.0
WH2_k127_165015_19 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000000000002318 133.0
WH2_k127_165015_2 Aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 2.264e-229 716.0
WH2_k127_165015_20 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000003533 115.0
WH2_k127_165015_3 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 524.0
WH2_k127_165015_4 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 478.0
WH2_k127_165015_5 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 428.0
WH2_k127_165015_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 381.0
WH2_k127_165015_7 PFAM ABC transporter K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 318.0
WH2_k127_165015_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000102 243.0
WH2_k127_165015_9 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000008707 251.0
WH2_k127_1674575_0 Branched-chain amino acid transport system / permease component K01997,K01998 - - 1.429e-257 808.0
WH2_k127_1674575_1 Aldehyde dehydrogenase family - - - 3.196e-211 667.0
WH2_k127_1674575_10 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 488.0
WH2_k127_1674575_11 helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 476.0
WH2_k127_1674575_12 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 464.0
WH2_k127_1674575_13 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 458.0
WH2_k127_1674575_14 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 433.0
WH2_k127_1674575_15 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 430.0
WH2_k127_1674575_16 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 406.0
WH2_k127_1674575_17 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 400.0
WH2_k127_1674575_18 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 388.0
WH2_k127_1674575_19 ATPases associated with a variety of cellular activities K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 378.0
WH2_k127_1674575_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 2.752e-199 631.0
WH2_k127_1674575_20 HAD superfamily, subfamily IIIB (Acid phosphatase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 372.0
WH2_k127_1674575_21 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 361.0
WH2_k127_1674575_22 enzyme related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000225 290.0
WH2_k127_1674575_23 transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002189 271.0
WH2_k127_1674575_24 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006731 266.0
WH2_k127_1674575_25 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000145 257.0
WH2_k127_1674575_26 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001416 248.0
WH2_k127_1674575_27 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000788 226.0
WH2_k127_1674575_28 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008973 235.0
WH2_k127_1674575_29 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000001987 203.0
WH2_k127_1674575_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 1.143e-194 616.0
WH2_k127_1674575_30 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000006981 222.0
WH2_k127_1674575_31 Protein of unknown function (DUF3833) - - - 0.0000000000000000000000000000000000000000000000000001235 193.0
WH2_k127_1674575_32 ChrR Cupin-like domain K07167 - - 0.000000000000000000000000000000000000000000000000002445 190.0
WH2_k127_1674575_33 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000009646 196.0
WH2_k127_1674575_34 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000000000000000000001409 180.0
WH2_k127_1674575_36 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000004446 173.0
WH2_k127_1674575_37 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000000000000005457 169.0
WH2_k127_1674575_38 SnoaL-like domain - - - 0.00000000000000000000000000000009678 130.0
WH2_k127_1674575_39 - - - - 0.000001328 51.0
WH2_k127_1674575_4 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 582.0
WH2_k127_1674575_40 Salmonella virulence plasmid 65kDa B protein - - - 0.0005899 51.0
WH2_k127_1674575_5 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 576.0
WH2_k127_1674575_6 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 538.0
WH2_k127_1674575_7 amine oxidase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 538.0
WH2_k127_1674575_8 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 551.0
WH2_k127_1674575_9 Cysteine synthase K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 499.0
WH2_k127_1676357_0 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 502.0
WH2_k127_1676357_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 436.0
WH2_k127_1676357_2 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000001538 174.0
WH2_k127_1676357_3 Domain of unknown function (DUF4974) K07165 - - 0.000000000000000000000000000000000000004068 160.0
WH2_k127_1676357_4 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000001549 127.0
WH2_k127_1676357_5 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000008811 122.0
WH2_k127_1676357_6 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.00000000000000000000000636 108.0
WH2_k127_1676357_7 TonB-dependent siderophore receptor - - - 0.0000000000006677 72.0
WH2_k127_1676357_8 Belongs to the peptidase S8 family - - - 0.0005545 52.0
WH2_k127_1677529_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 396.0
WH2_k127_1677529_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 374.0
WH2_k127_1677529_2 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002884 279.0
WH2_k127_1677529_3 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000008406 214.0
WH2_k127_1677529_4 YGGT family K02221 - - 0.0000000000000000000000000001759 120.0
WH2_k127_1677529_5 Belongs to the UPF0235 family K09131 - - 0.00000000000000000006474 93.0
WH2_k127_1696121_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 2.813e-194 612.0
WH2_k127_1696121_1 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 425.0
WH2_k127_1696121_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001574 256.0
WH2_k127_1696121_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003966 243.0
WH2_k127_1696121_4 PepSY-associated TM region K00380 - 1.8.1.2 0.0000000000000000000000004908 107.0
WH2_k127_1798713_0 Enoyl-CoA hydratase/isomerase K20765 - 3.7.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 406.0
WH2_k127_1798713_1 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 298.0
WH2_k127_1798713_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 288.0
WH2_k127_1856045_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2229.0
WH2_k127_1856045_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1048.0
WH2_k127_1856045_10 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 526.0
WH2_k127_1856045_11 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 423.0
WH2_k127_1856045_12 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 410.0
WH2_k127_1856045_13 carbohydrate kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 433.0
WH2_k127_1856045_14 ABC transporter, ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 411.0
WH2_k127_1856045_15 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 401.0
WH2_k127_1856045_16 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 356.0
WH2_k127_1856045_17 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 342.0
WH2_k127_1856045_18 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 323.0
WH2_k127_1856045_19 Methyl-accepting chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 342.0
WH2_k127_1856045_2 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 3.253e-230 720.0
WH2_k127_1856045_20 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000004773 268.0
WH2_k127_1856045_21 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001079 262.0
WH2_k127_1856045_22 2Fe-2S iron-sulfur cluster binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000001368 256.0
WH2_k127_1856045_23 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007472 259.0
WH2_k127_1856045_24 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000006207 237.0
WH2_k127_1856045_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006554 237.0
WH2_k127_1856045_26 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000000000000000000000001131 198.0
WH2_k127_1856045_27 Putative lumazine-binding - - - 0.000000000000000000000000000000000000000000000001597 176.0
WH2_k127_1856045_28 Lipoate-protein ligase - - - 0.0000000000000000000000000000000000000003738 157.0
WH2_k127_1856045_29 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000007809 136.0
WH2_k127_1856045_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 1.039e-211 670.0
WH2_k127_1856045_30 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000001375 112.0
WH2_k127_1856045_31 Biotin-requiring enzyme - - - 0.00000000000000000000001755 101.0
WH2_k127_1856045_32 Protein conserved in bacteria K09774 - - 0.00000000000000000002798 99.0
WH2_k127_1856045_33 Protein of unknown function (DUF1150) - - - 0.00000001723 58.0
WH2_k127_1856045_4 glutamate--cysteine ligase K01919 - 6.3.2.2 5.552e-209 659.0
WH2_k127_1856045_5 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.454e-195 619.0
WH2_k127_1856045_6 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 589.0
WH2_k127_1856045_7 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 556.0
WH2_k127_1856045_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 548.0
WH2_k127_1856045_9 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 533.0
WH2_k127_1858968_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1772.0
WH2_k127_1858968_1 Sulfatase - - - 2.515e-245 782.0
WH2_k127_1858968_10 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 538.0
WH2_k127_1858968_11 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 520.0
WH2_k127_1858968_12 PFAM HI0933 family protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 522.0
WH2_k127_1858968_13 ABC-type sugar transport system, permease component K10119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 487.0
WH2_k127_1858968_14 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 469.0
WH2_k127_1858968_15 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 427.0
WH2_k127_1858968_16 Voltage-dependent anion channel K03304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 407.0
WH2_k127_1858968_17 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 414.0
WH2_k127_1858968_18 Protein conserved in bacteria K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 387.0
WH2_k127_1858968_19 AsmA-like C-terminal region K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 393.0
WH2_k127_1858968_2 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.386e-225 704.0
WH2_k127_1858968_20 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 306.0
WH2_k127_1858968_21 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007531 271.0
WH2_k127_1858968_22 COG0642 Signal transduction histidine kinase K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001005 284.0
WH2_k127_1858968_23 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000004877 261.0
WH2_k127_1858968_24 Glutathione S-transferase, N-terminal domain K01801 - 5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002604 253.0
WH2_k127_1858968_25 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008475 241.0
WH2_k127_1858968_26 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000003744 210.0
WH2_k127_1858968_27 Two component transcriptional regulator, winged helix family K07774 - - 0.0000000000000000000000000000000000000000000000000000000002847 210.0
WH2_k127_1858968_28 Inner membrane component domain - - - 0.000000000000000000000000000000000000000000000007121 175.0
WH2_k127_1858968_29 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000003827 172.0
WH2_k127_1858968_3 ABC transporter substrate-binding protein K10117 - - 4.472e-206 648.0
WH2_k127_1858968_30 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000001951 173.0
WH2_k127_1858968_31 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000002226 173.0
WH2_k127_1858968_32 COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000001231 161.0
WH2_k127_1858968_33 Glutathione S-transferase, N-terminal domain K01801 - 5.2.1.4 0.000000000000000000000000000000000002438 139.0
WH2_k127_1858968_34 NADH ubiquinone oxidoreductase 17.2 kD subunit - - - 0.00000000000000000000000000000000001576 150.0
WH2_k127_1858968_35 PFAM extracellular solute-binding protein family 1 K02012 - - 0.000000000000000000000000008377 113.0
WH2_k127_1858968_36 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000001885 109.0
WH2_k127_1858968_37 DNA-binding transcription factor activity K06075 - - 0.00000003742 61.0
WH2_k127_1858968_4 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 602.0
WH2_k127_1858968_5 AMP-binding enzyme K12508 - 6.2.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 604.0
WH2_k127_1858968_6 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 574.0
WH2_k127_1858968_7 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000093 571.0
WH2_k127_1858968_8 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 559.0
WH2_k127_1858968_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 539.0
WH2_k127_1914147_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.272e-288 896.0
WH2_k127_1914147_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 606.0
WH2_k127_1914147_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 597.0
WH2_k127_1914147_3 Acetolactate synthase small K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001987 261.0
WH2_k127_1914147_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000001019 138.0
WH2_k127_1914147_5 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000003628 133.0
WH2_k127_1914958_0 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 591.0
WH2_k127_1914958_1 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 566.0
WH2_k127_1914958_10 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 294.0
WH2_k127_1914958_11 lactoylglutathione lyase activity K07032,K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004267 257.0
WH2_k127_1914958_12 dehydrogenase and related dehydrogenases K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000003482 252.0
WH2_k127_1914958_13 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000279 250.0
WH2_k127_1914958_14 transcriptional K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000005319 226.0
WH2_k127_1914958_15 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000001404 237.0
WH2_k127_1914958_16 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine - - - 0.000000000000000000000000000000000000000000000000000000000000004334 223.0
WH2_k127_1914958_17 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000005541 198.0
WH2_k127_1914958_18 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000000000000001093 186.0
WH2_k127_1914958_19 Transcriptional regulator K05964 - 2.7.7.61 0.0000000000000000000000000000000008745 138.0
WH2_k127_1914958_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 524.0
WH2_k127_1914958_3 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 406.0
WH2_k127_1914958_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 390.0
WH2_k127_1914958_5 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 381.0
WH2_k127_1914958_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 389.0
WH2_k127_1914958_7 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 376.0
WH2_k127_1914958_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 351.0
WH2_k127_1914958_9 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 340.0
WH2_k127_1941565_0 NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein - - - 5.433e-247 797.0
WH2_k127_1941565_1 belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 1.244e-235 743.0
WH2_k127_1941565_10 Binding-protein-dependent transport system inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 352.0
WH2_k127_1941565_11 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 349.0
WH2_k127_1941565_12 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 317.0
WH2_k127_1941565_13 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 296.0
WH2_k127_1941565_14 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 299.0
WH2_k127_1941565_15 Binding-protein-dependent transport system inner membrane component K11078 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004702 286.0
WH2_k127_1941565_16 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000001471 279.0
WH2_k127_1941565_17 HlyD family secretion protein K02022 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001477 254.0
WH2_k127_1941565_18 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000004025 217.0
WH2_k127_1941565_19 endo-beta-N-acetylglucosaminidase K01227 GO:0000270,GO:0000323,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005829,GO:0005975,GO:0006022,GO:0006026,GO:0006027,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0008092,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009100,GO:0009253,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0015929,GO:0016052,GO:0016231,GO:0016787,GO:0016798,GO:0017022,GO:0019538,GO:0030203,GO:0033925,GO:0035821,GO:0036211,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044033,GO:0044035,GO:0044040,GO:0044041,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044278,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051672,GO:0051704,GO:0051707,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.2.1.96 0.00000000000000000000000000000000000000000000000000000006356 221.0
WH2_k127_1941565_2 NHLM bacteriocin system ABC transporter, ATP-binding protein K06148 - - 5.768e-199 653.0
WH2_k127_1941565_20 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000007661 188.0
WH2_k127_1941565_21 Permeases of the drug metabolite transporter (DMT) superfamily K15269 - - 0.0000000000000000000000000000000000000000000000000007917 186.0
WH2_k127_1941565_22 Aspartyl/Asparaginyl beta-hydroxylase K12979 - - 0.0000000000000000000000000000000000000000000000002204 180.0
WH2_k127_1941565_23 - - - - 0.000000000000000000000000000000000000000000000004323 190.0
WH2_k127_1941565_24 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01955,K03802,K05844 - 6.3.2.29,6.3.2.30,6.3.5.5 0.00000000000000000000000000000000000002736 154.0
WH2_k127_1941565_25 SNARE associated Golgi protein - - - 0.0000000000000000000000000000846 117.0
WH2_k127_1941565_27 Acetyltransferase (GNAT) family - - - 0.0007173 51.0
WH2_k127_1941565_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 550.0
WH2_k127_1941565_4 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 515.0
WH2_k127_1941565_5 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 512.0
WH2_k127_1941565_6 FAD FMN-containing dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 497.0
WH2_k127_1941565_7 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 477.0
WH2_k127_1941565_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 455.0
WH2_k127_1941565_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 376.0
WH2_k127_1944483_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 3.408e-235 743.0
WH2_k127_1944483_1 COG1960 Acyl-CoA dehydrogenases K20035 - - 5.047e-225 712.0
WH2_k127_1944483_10 MotA TolQ ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 370.0
WH2_k127_1944483_11 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 366.0
WH2_k127_1944483_12 Belongs to the nlpA lipoprotein family K02073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 361.0
WH2_k127_1944483_13 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 362.0
WH2_k127_1944483_14 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 361.0
WH2_k127_1944483_15 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 356.0
WH2_k127_1944483_16 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 364.0
WH2_k127_1944483_17 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 371.0
WH2_k127_1944483_18 AI-2E family transporter K03548 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 348.0
WH2_k127_1944483_19 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 333.0
WH2_k127_1944483_2 ABC-type multidrug transport system, ATPase and permease K06147 - - 1.622e-217 698.0
WH2_k127_1944483_20 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 318.0
WH2_k127_1944483_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 306.0
WH2_k127_1944483_22 LysR substrate binding domain K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003076 286.0
WH2_k127_1944483_23 ABC-type metal ion transport system, permease component K02072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000294 275.0
WH2_k127_1944483_24 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008309 275.0
WH2_k127_1944483_25 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000394 277.0
WH2_k127_1944483_26 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000001993 238.0
WH2_k127_1944483_27 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000001592 239.0
WH2_k127_1944483_28 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000007301 223.0
WH2_k127_1944483_29 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000000676 205.0
WH2_k127_1944483_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 597.0
WH2_k127_1944483_30 Uncharacterized protein conserved in bacteria (DUF2066) - - - 0.000000000000000000000000000000000000000000000000000000007132 213.0
WH2_k127_1944483_31 COG0593 ATPase involved in DNA replication initiation - - - 0.000000000000000000000000000000000000000000000000000003375 212.0
WH2_k127_1944483_32 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000000001269 188.0
WH2_k127_1944483_33 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000009319 177.0
WH2_k127_1944483_34 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000003404 167.0
WH2_k127_1944483_35 multidrug resistance K15549 GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015546,GO:0015893,GO:0015906,GO:0022857,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0042891,GO:0042895,GO:0042908,GO:0042910,GO:0045117,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072348,GO:1901474,GO:1901682,GO:1902599 - 0.0000000000000000000000000000000000000000001618 169.0
WH2_k127_1944483_36 Phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000000000000000005273 148.0
WH2_k127_1944483_37 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000009834 140.0
WH2_k127_1944483_38 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000000000000003521 124.0
WH2_k127_1944483_39 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000001042 119.0
WH2_k127_1944483_4 aminotransferase class I and II K00643 - 2.3.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 581.0
WH2_k127_1944483_40 Fusaric acid resistance protein family - - - 0.0000000000000000000000006634 121.0
WH2_k127_1944483_41 COG2885 outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - 0.000000000000004719 79.0
WH2_k127_1944483_42 Uncharacterised protein family - - - 0.00000009906 58.0
WH2_k127_1944483_5 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 490.0
WH2_k127_1944483_6 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 467.0
WH2_k127_1944483_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 400.0
WH2_k127_1944483_8 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system K02071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 399.0
WH2_k127_1944483_9 flagellar motor protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 378.0
WH2_k127_1954558_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.668e-272 854.0
WH2_k127_1954558_1 dioxygenase K11159 - - 1.643e-228 717.0
WH2_k127_1954558_10 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 413.0
WH2_k127_1954558_11 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 375.0
WH2_k127_1954558_12 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 383.0
WH2_k127_1954558_13 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 357.0
WH2_k127_1954558_14 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 327.0
WH2_k127_1954558_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 331.0
WH2_k127_1954558_16 Lysophospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 319.0
WH2_k127_1954558_17 Isocitrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 324.0
WH2_k127_1954558_18 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 321.0
WH2_k127_1954558_19 TIGRFAM phosphate regulon transcriptional regulatory protein PhoB K07657,K07659,K18144 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 311.0
WH2_k127_1954558_2 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 4.603e-199 627.0
WH2_k127_1954558_20 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 308.0
WH2_k127_1954558_21 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K18143 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 313.0
WH2_k127_1954558_22 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 290.0
WH2_k127_1954558_23 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 292.0
WH2_k127_1954558_24 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001459 277.0
WH2_k127_1954558_25 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001374 281.0
WH2_k127_1954558_26 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004286 265.0
WH2_k127_1954558_27 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006125 266.0
WH2_k127_1954558_28 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009972 257.0
WH2_k127_1954558_29 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002207 260.0
WH2_k127_1954558_3 Amidase K01426 - 3.5.1.4 2.026e-196 623.0
WH2_k127_1954558_30 abc transporter atp-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001361 256.0
WH2_k127_1954558_31 Uracil-DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001424 258.0
WH2_k127_1954558_32 Belongs to the LeuD family K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000004414 248.0
WH2_k127_1954558_33 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000004736 244.0
WH2_k127_1954558_34 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000007208 235.0
WH2_k127_1954558_35 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000244 229.0
WH2_k127_1954558_36 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000009149 226.0
WH2_k127_1954558_37 pathogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000005519 240.0
WH2_k127_1954558_38 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000002469 218.0
WH2_k127_1954558_39 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000007178 215.0
WH2_k127_1954558_4 Belongs to the thiolase family K00626 - 2.3.1.9 2.303e-196 621.0
WH2_k127_1954558_40 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000005316 224.0
WH2_k127_1954558_41 Bacterial transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000003329 212.0
WH2_k127_1954558_42 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000002886 190.0
WH2_k127_1954558_43 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000003008 182.0
WH2_k127_1954558_44 Secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000224 183.0
WH2_k127_1954558_45 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000004394 178.0
WH2_k127_1954558_46 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000005806 152.0
WH2_k127_1954558_47 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000001409 155.0
WH2_k127_1954558_48 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000008073 150.0
WH2_k127_1954558_49 - - - - 0.0000000000000000000000000000000000006565 141.0
WH2_k127_1954558_5 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 514.0
WH2_k127_1954558_50 - - - - 0.0000000000000000000000002761 124.0
WH2_k127_1954558_51 Small Multidrug Resistance protein K03297 - - 0.0000000000000000000000009596 107.0
WH2_k127_1954558_52 PAS domain - - - 0.0000000000004653 76.0
WH2_k127_1954558_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 494.0
WH2_k127_1954558_7 Polysaccharide deacetylase K01452 - 3.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 444.0
WH2_k127_1954558_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 439.0
WH2_k127_1954558_9 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K21323 - 1.14.13.229,1.14.19.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 430.0
WH2_k127_1959245_0 FAD linked oxidases, C-terminal domain - - - 1.703e-256 796.0
WH2_k127_1959245_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.592e-227 708.0
WH2_k127_1959245_10 Stimulus-sensing domain K14980 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 485.0
WH2_k127_1959245_11 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 472.0
WH2_k127_1959245_12 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 486.0
WH2_k127_1959245_13 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 487.0
WH2_k127_1959245_14 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 463.0
WH2_k127_1959245_15 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 427.0
WH2_k127_1959245_16 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 417.0
WH2_k127_1959245_17 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 410.0
WH2_k127_1959245_18 ABC-type amino acid transport system permease component K02029,K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 389.0
WH2_k127_1959245_19 abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 399.0
WH2_k127_1959245_2 FAD dependent oxidoreductase K00285 - 1.4.5.1 7.13e-217 679.0
WH2_k127_1959245_20 Protocatechuate 3,4-dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 367.0
WH2_k127_1959245_21 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 381.0
WH2_k127_1959245_22 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 362.0
WH2_k127_1959245_23 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 353.0
WH2_k127_1959245_24 Transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 351.0
WH2_k127_1959245_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 363.0
WH2_k127_1959245_26 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 311.0
WH2_k127_1959245_27 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 297.0
WH2_k127_1959245_28 Plasmid encoded RepA protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 292.0
WH2_k127_1959245_29 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 298.0
WH2_k127_1959245_3 Belongs to the thiolase family K07823 - 2.3.1.174 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 595.0
WH2_k127_1959245_30 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 290.0
WH2_k127_1959245_31 glutathione transferase activity K00799,K03675 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005378 271.0
WH2_k127_1959245_32 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000005389 269.0
WH2_k127_1959245_33 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009923 247.0
WH2_k127_1959245_34 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000001425 226.0
WH2_k127_1959245_35 protocatechuate 3,4-dioxygenase, alpha K00448 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000004762 233.0
WH2_k127_1959245_36 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000125 208.0
WH2_k127_1959245_37 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.00000000000000000000000000000000000000000000000000000002686 199.0
WH2_k127_1959245_38 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000003029 183.0
WH2_k127_1959245_39 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000006119 167.0
WH2_k127_1959245_4 Amidohydrolase family K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 584.0
WH2_k127_1959245_40 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000607 160.0
WH2_k127_1959245_41 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000009729 155.0
WH2_k127_1959245_42 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism K06023 - - 0.0000000000000000000000000000000000000002787 154.0
WH2_k127_1959245_43 Putative inner membrane exporter, YdcZ K09936 - - 0.000000000000000000000000000000000004276 149.0
WH2_k127_1959245_44 invasion associated locus B - - - 0.0000000000000000000000000000001045 130.0
WH2_k127_1959245_45 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000001688 132.0
WH2_k127_1959245_46 YCII-related domain K09780 - - 0.0000000000000000000000001584 109.0
WH2_k127_1959245_47 TIGRFAM phosphocarrier, HPr family K11189 - - 0.000000000000000000000001047 107.0
WH2_k127_1959245_48 - - - - 0.000000000000000000000001094 107.0
WH2_k127_1959245_49 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000001098 109.0
WH2_k127_1959245_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 565.0
WH2_k127_1959245_50 WxcM-like, C-terminal - - - 0.0000000000000000000008936 106.0
WH2_k127_1959245_51 WHG domain - - - 0.000000000000003152 83.0
WH2_k127_1959245_52 Tautomerase enzyme - - - 0.0000000001143 66.0
WH2_k127_1959245_53 - - - - 0.000002452 55.0
WH2_k127_1959245_6 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 557.0
WH2_k127_1959245_7 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 539.0
WH2_k127_1959245_8 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 515.0
WH2_k127_1959245_9 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 501.0
WH2_k127_1989307_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 545.0
WH2_k127_1989307_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 336.0
WH2_k127_1989307_2 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 317.0
WH2_k127_1989307_3 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002246 248.0
WH2_k127_1989307_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005104 246.0
WH2_k127_1989307_5 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000008123 89.0
WH2_k127_2033970_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.438e-309 960.0
WH2_k127_2033970_1 Thiolase, C-terminal domain - - - 1.985e-203 648.0
WH2_k127_2033970_10 OpgC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 316.0
WH2_k127_2033970_11 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 309.0
WH2_k127_2033970_12 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 294.0
WH2_k127_2033970_13 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 296.0
WH2_k127_2033970_14 branched-chain amino acid transport K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 305.0
WH2_k127_2033970_15 Ankyrin repeat K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001425 276.0
WH2_k127_2033970_16 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001271 247.0
WH2_k127_2033970_17 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000003549 242.0
WH2_k127_2033970_18 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000003136 229.0
WH2_k127_2033970_19 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.000000000000000000000000000000000000000000000000000002384 201.0
WH2_k127_2033970_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 4.723e-196 627.0
WH2_k127_2033970_20 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000001843 194.0
WH2_k127_2033970_21 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000522 165.0
WH2_k127_2033970_22 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000007065 169.0
WH2_k127_2033970_23 GGDEF domain - - - 0.0000000000000000000000000000000000001097 159.0
WH2_k127_2033970_24 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000003932 120.0
WH2_k127_2033970_25 TK COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K02479 - - 0.000000000000000000000001513 111.0
WH2_k127_2033970_26 cheY-homologous receiver domain - - - 0.0000000000000000000001208 103.0
WH2_k127_2033970_27 Histidine kinase - - - 0.00000000002191 70.0
WH2_k127_2033970_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 5.811e-194 628.0
WH2_k127_2033970_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 521.0
WH2_k127_2033970_5 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 466.0
WH2_k127_2033970_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 456.0
WH2_k127_2033970_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 365.0
WH2_k127_2033970_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 364.0
WH2_k127_2033970_9 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 337.0
WH2_k127_2091642_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1592.0
WH2_k127_2091642_1 oligoendopeptidase F K08602 - - 1.14e-232 741.0
WH2_k127_2091642_10 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 0.00000000000000000000000000000000000004262 160.0
WH2_k127_2091642_11 protein, possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000008605 147.0
WH2_k127_2091642_12 Membrane protein implicated in regulation of membrane protease activity K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000006063 119.0
WH2_k127_2091642_13 Bacterial aa3 type cytochrome c oxidase subunit IV - - - 0.0009594 44.0
WH2_k127_2091642_2 ABC1 family - - - 1.036e-195 623.0
WH2_k127_2091642_3 transhydrogenase subunit alpha K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 502.0
WH2_k127_2091642_4 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 472.0
WH2_k127_2091642_5 epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 434.0
WH2_k127_2091642_6 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 379.0
WH2_k127_2091642_7 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 332.0
WH2_k127_2091642_8 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002366 261.0
WH2_k127_2091642_9 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000002196 160.0
WH2_k127_2094792_0 Protein of unknown function (DUF1173) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 446.0
WH2_k127_2094792_1 TIGRFAM Ti-type conjugative transfer relaxase TraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 377.0
WH2_k127_2094792_2 Domain of unknown function (DUF1738) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 339.0
WH2_k127_2094792_3 N-6 DNA Methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 333.0
WH2_k127_2094792_4 Toprim domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002387 245.0
WH2_k127_2094792_5 Staphylococcal nuclease homologue - - - 0.00000000000000000000000000000000000000000000000000008049 194.0
WH2_k127_2094792_6 hydrolases of HD superfamily K06952 - - 0.00000000000000000000000002127 121.0
WH2_k127_2094792_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.0000002927 57.0
WH2_k127_2094792_9 Conjugal transfer protein TraD - - - 0.0004021 47.0
WH2_k127_2106466_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 1.267e-215 675.0
WH2_k127_2106466_1 Aldehyde dehydrogenase K00128 - 1.2.1.3 7.426e-208 656.0
WH2_k127_2106466_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 340.0
WH2_k127_2106466_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000216 245.0
WH2_k127_2106466_4 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001286 240.0
WH2_k127_2106466_5 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000002525 242.0
WH2_k127_2106466_6 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000001003 142.0
WH2_k127_215005_0 Amidohydrolase family K01485 - 3.5.4.1 8.424e-212 674.0
WH2_k127_215005_1 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 412.0
WH2_k127_215005_2 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 385.0
WH2_k127_215005_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 295.0
WH2_k127_215005_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000178 171.0
WH2_k127_215005_5 NIPSNAP - - - 0.000000000000001559 80.0
WH2_k127_2150183_0 Cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 610.0
WH2_k127_2150183_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 524.0
WH2_k127_2150183_10 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000002799 222.0
WH2_k127_2150183_11 Acetyltransferase (GNAT) domain K03828 - - 0.0000000000000000000000000000000000000000000000000000004475 198.0
WH2_k127_2150183_12 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00002848 49.0
WH2_k127_2150183_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 438.0
WH2_k127_2150183_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 387.0
WH2_k127_2150183_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 344.0
WH2_k127_2150183_5 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 353.0
WH2_k127_2150183_6 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 335.0
WH2_k127_2150183_7 Chaperone SurA K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 299.0
WH2_k127_2150183_8 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 293.0
WH2_k127_2150183_9 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001137 251.0
WH2_k127_2177745_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1226.0
WH2_k127_2177745_1 PFAM Extracellular solute-binding protein, family 3 K01713 - 4.2.1.51,4.2.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 395.0
WH2_k127_2177745_2 Belongs to the NadC ModD family K00767,K03813 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 321.0
WH2_k127_2177745_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008162 257.0
WH2_k127_2177745_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000006277 165.0
WH2_k127_2217509_0 Belongs to the GcvT family K19191 - 1.5.3.19 0.0 1156.0
WH2_k127_2217509_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0 1062.0
WH2_k127_2217509_10 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000005228 182.0
WH2_k127_2217509_11 PFAM regulatory protein DeoR K02444 - - 0.0000000000000000000000000000000000000000000000001687 200.0
WH2_k127_2217509_12 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000007087 166.0
WH2_k127_2217509_13 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000087 164.0
WH2_k127_2217509_2 trehalose synthase K05343 - 3.2.1.1,5.4.99.16 2.19e-293 904.0
WH2_k127_2217509_3 Peptidase family M20/M25/M40 - - - 4.214e-213 675.0
WH2_k127_2217509_4 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 2.207e-202 636.0
WH2_k127_2217509_5 Rieske [2Fe-2S] domain K21323 - 1.14.13.229,1.14.19.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 595.0
WH2_k127_2217509_6 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 436.0
WH2_k127_2217509_7 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 382.0
WH2_k127_2217509_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 325.0
WH2_k127_2217509_9 Polypeptide deformylase K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000002413 219.0
WH2_k127_2262660_0 Circadian clock protein KaiC K08482 - - 3.392e-222 698.0
WH2_k127_2262660_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.396e-211 663.0
WH2_k127_2262660_10 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 314.0
WH2_k127_2262660_11 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 312.0
WH2_k127_2262660_12 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002019 273.0
WH2_k127_2262660_13 Glycosyl transferase family 41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000355 293.0
WH2_k127_2262660_14 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000004903 226.0
WH2_k127_2262660_15 Protein of unknown function (DUF4239) - - - 0.000000000004229 80.0
WH2_k127_2262660_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 566.0
WH2_k127_2262660_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 471.0
WH2_k127_2262660_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 400.0
WH2_k127_2262660_5 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 398.0
WH2_k127_2262660_6 phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 376.0
WH2_k127_2262660_7 Alpha beta hydrolase K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 366.0
WH2_k127_2262660_8 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 342.0
WH2_k127_2262660_9 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 335.0
WH2_k127_2352007_0 Secretin and TonB N terminus short domain K02014 - - 7.051e-211 676.0
WH2_k127_2352007_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 3.943e-207 648.0
WH2_k127_2352007_10 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.000000000000000000000000000000000000000000000005361 196.0
WH2_k127_2352007_11 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000004269 101.0
WH2_k127_2352007_12 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000000000004305 86.0
WH2_k127_2352007_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 509.0
WH2_k127_2352007_3 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 404.0
WH2_k127_2352007_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 354.0
WH2_k127_2352007_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 345.0
WH2_k127_2352007_6 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 341.0
WH2_k127_2352007_7 Predicted integral membrane protein (DUF2270) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 288.0
WH2_k127_2352007_8 Aminoacyl-tRNA editing domain K03976 GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004018 260.0
WH2_k127_2352007_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000344 259.0
WH2_k127_2362908_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335 - 1.6.5.3 1.96e-260 812.0
WH2_k127_2362908_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 502.0
WH2_k127_2362908_10 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 357.0
WH2_k127_2362908_11 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 317.0
WH2_k127_2362908_12 Molybdenum ABC transporter K02020 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 295.0
WH2_k127_2362908_13 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 310.0
WH2_k127_2362908_14 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000457 279.0
WH2_k127_2362908_15 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006534 275.0
WH2_k127_2362908_16 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000003354 254.0
WH2_k127_2362908_17 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007529 252.0
WH2_k127_2362908_18 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00127 - - 0.0000000000000000000000000000000000000000000000000000000000001122 217.0
WH2_k127_2362908_19 COQ9 K18587 - - 0.0000000000000000000000000000000000000000000000000000000000001467 218.0
WH2_k127_2362908_2 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 475.0
WH2_k127_2362908_20 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000000000000003064 218.0
WH2_k127_2362908_21 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000003517 216.0
WH2_k127_2362908_22 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000254 211.0
WH2_k127_2362908_23 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000002325 206.0
WH2_k127_2362908_24 DeoR C terminal sensor domain K02444 - - 0.0000000000000000000000000000000000009762 140.0
WH2_k127_2362908_25 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000001324 143.0
WH2_k127_2362908_26 pathogenesis - - - 0.0000000000000000004463 103.0
WH2_k127_2362908_27 Pfam:DUF1311 - - - 0.00000000008957 74.0
WH2_k127_2362908_28 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00123 - 1.17.1.9 0.0000000003029 70.0
WH2_k127_2362908_29 pyrroloquinoline quinone binding - - - 0.000000008408 67.0
WH2_k127_2362908_3 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 477.0
WH2_k127_2362908_30 - - - - 0.00000006314 66.0
WH2_k127_2362908_4 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 444.0
WH2_k127_2362908_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 413.0
WH2_k127_2362908_6 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 411.0
WH2_k127_2362908_7 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 399.0
WH2_k127_2362908_8 PFAM CBS domain containing protein K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 359.0
WH2_k127_2362908_9 Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 349.0
WH2_k127_2370237_0 Aconitase family (aconitate hydratase) K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1295.0
WH2_k127_2370237_1 TonB dependent receptor K02014 - - 2.457e-269 847.0
WH2_k127_2370237_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 357.0
WH2_k127_2370237_3 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002818 274.0
WH2_k127_2370237_4 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001576 256.0
WH2_k127_2370237_5 CBS domain - - - 0.00000000000000000000000000000000000000001348 158.0
WH2_k127_2370237_6 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000006005 143.0
WH2_k127_2370237_7 - - - - 0.0000000000000000000000003095 111.0
WH2_k127_2404845_0 Protein of unknown function (DUF2975) - - - 0.00000000000000000000000000000000000000000000001769 177.0
WH2_k127_2404845_1 transcriptional regulator K07727 - - 0.000000000000000000000000000001281 121.0
WH2_k127_2404845_2 Fic/DOC family N-terminal - - - 0.00000000000000002928 86.0
WH2_k127_2404845_3 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000001032 53.0
WH2_k127_2404845_4 - - - - 0.000002366 53.0
WH2_k127_2404845_5 - - - - 0.0000107 56.0
WH2_k127_2404845_6 - - - - 0.00004089 51.0
WH2_k127_2415729_0 Receptor family ligand binding region - - - 3.182e-200 632.0
WH2_k127_2415729_1 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 447.0
WH2_k127_2415729_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 456.0
WH2_k127_2415729_3 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 383.0
WH2_k127_2415729_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02049,K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 376.0
WH2_k127_2415729_5 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 333.0
WH2_k127_2415729_6 branched-chain amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 334.0
WH2_k127_2415729_7 Gaf domain - - - 0.0000000000000000000000000000000000000000000000000000000000001883 221.0
WH2_k127_2415729_8 ATPases associated with a variety of cellular activities K01995,K11957 - - 0.000000000000000000000000000000000001886 143.0
WH2_k127_2415729_9 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000004978 68.0
WH2_k127_2429116_0 HELICc2 K03722 - 3.6.4.12 0.0 1027.0
WH2_k127_2429116_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 9.883e-253 788.0
WH2_k127_2429116_10 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 462.0
WH2_k127_2429116_11 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 441.0
WH2_k127_2429116_12 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 415.0
WH2_k127_2429116_13 Dihydroorotate dehydrogenase (quinone) K00254 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044205,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 406.0
WH2_k127_2429116_14 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 379.0
WH2_k127_2429116_15 Flagellar hook protein FlgE K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 332.0
WH2_k127_2429116_16 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 306.0
WH2_k127_2429116_17 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 301.0
WH2_k127_2429116_18 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002087 293.0
WH2_k127_2429116_19 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002161 272.0
WH2_k127_2429116_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.667e-247 773.0
WH2_k127_2429116_20 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003321 260.0
WH2_k127_2429116_21 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004282 252.0
WH2_k127_2429116_22 Transmembrane protein 43 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001472 248.0
WH2_k127_2429116_23 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000003059 231.0
WH2_k127_2429116_24 EcsC protein family - - - 0.00000000000000000000000000000000000000000000000000000000000003041 229.0
WH2_k127_2429116_25 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000004023 224.0
WH2_k127_2429116_26 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000009076 237.0
WH2_k127_2429116_27 Peptidase S24-like - - - 0.000000000000000000000000000000000000000000000000000007369 198.0
WH2_k127_2429116_28 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000001185 204.0
WH2_k127_2429116_29 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000001551 196.0
WH2_k127_2429116_3 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 1.134e-232 730.0
WH2_k127_2429116_30 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000002969 198.0
WH2_k127_2429116_31 Bacterial regulatory helix-turn-helix protein, lysR family K03566,K17850 - - 0.00000000000000000000000000000000000000000001375 173.0
WH2_k127_2429116_32 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000003079 147.0
WH2_k127_2429116_33 Belongs to the flagella basal body rod proteins family K02396 - - 0.000000000000000000000000000000000001025 158.0
WH2_k127_2429116_34 methyltransferase - - - 0.000000000000000000000000000002199 134.0
WH2_k127_2429116_35 Belongs to the UPF0312 family - - - 0.00000000000000000000000000001677 128.0
WH2_k127_2429116_36 flagellar hook-associated protein K02396 - - 0.00000000000000000000000004064 124.0
WH2_k127_2429116_37 Protein of unknown function (DUF952) - - - 0.000000000000000000007544 97.0
WH2_k127_2429116_38 cytochrome b561 K12262 - - 0.0000000000000000001815 96.0
WH2_k127_2429116_39 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000001084 79.0
WH2_k127_2429116_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.112e-215 681.0
WH2_k127_2429116_40 - - - - 0.0000000000000001533 86.0
WH2_k127_2429116_41 Rod binding protein - - - 0.0000000000002101 79.0
WH2_k127_2429116_42 Belongs to the flagella basal body rod proteins family K02396 - - 0.000000001428 71.0
WH2_k127_2429116_43 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - 0.000000004888 68.0
WH2_k127_2429116_44 Tetratricopeptide repeat - - - 0.00000001906 63.0
WH2_k127_2429116_46 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.0006732 51.0
WH2_k127_2429116_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 553.0
WH2_k127_2429116_6 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 533.0
WH2_k127_2429116_7 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 511.0
WH2_k127_2429116_8 PFAM phospholipase D Transphosphatidylase K01115 - 3.1.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 511.0
WH2_k127_2429116_9 IrrE N-terminal-like domain K21686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 489.0
WH2_k127_2456840_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 572.0
WH2_k127_2456840_1 COG2309 Leucyl aminopeptidase (aminopeptidase T) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 494.0
WH2_k127_2456840_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000001369 151.0
WH2_k127_2456840_2 Hsp70 protein K04046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 494.0
WH2_k127_2456840_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 492.0
WH2_k127_2456840_4 Patatin phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 453.0
WH2_k127_2456840_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 GO:0000003,GO:0000166,GO:0001568,GO:0001676,GO:0001944,GO:0003674,GO:0003824,GO:0004888,GO:0004930,GO:0004953,GO:0004954,GO:0004955,GO:0004957,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007186,GO:0007275,GO:0007276,GO:0007292,GO:0007565,GO:0007567,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009653,GO:0009719,GO:0009987,GO:0010033,GO:0016053,GO:0016404,GO:0016491,GO:0016614,GO:0016616,GO:0019372,GO:0019752,GO:0019953,GO:0022414,GO:0023052,GO:0030728,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0033559,GO:0035239,GO:0035295,GO:0036094,GO:0038023,GO:0042221,GO:0042759,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0045786,GO:0046394,GO:0046456,GO:0046983,GO:0048037,GO:0048514,GO:0048519,GO:0048523,GO:0048609,GO:0048731,GO:0048844,GO:0048856,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051287,GO:0051704,GO:0051716,GO:0051726,GO:0055114,GO:0060089,GO:0060840,GO:0065007,GO:0070013,GO:0070403,GO:0070493,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0072330,GO:0072358,GO:0072359,GO:0097070,GO:0097159,GO:1901265,GO:1901363,GO:1901568,GO:1901570,GO:1901576,GO:2001300,GO:2001301 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 431.0
WH2_k127_2456840_6 Acetoacetate decarboxylase (ADC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 404.0
WH2_k127_2456840_7 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 369.0
WH2_k127_2456840_8 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000008756 233.0
WH2_k127_2456840_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000825 186.0
WH2_k127_2475286_0 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 476.0
WH2_k127_2475286_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K05934,K13541 - 2.1.1.131,3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 464.0
WH2_k127_2475286_10 Nitrite/Sulfite reductase ferredoxin-like half domain K02229 - 1.14.13.83 0.00000000000000000000000000000000000000000000000000000005629 210.0
WH2_k127_2475286_11 - - - - 0.0000000000000000000002307 100.0
WH2_k127_2475286_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 432.0
WH2_k127_2475286_3 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 317.0
WH2_k127_2475286_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 325.0
WH2_k127_2475286_5 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 304.0
WH2_k127_2475286_6 Tetrapyrrole (Corrin/Porphyrin) Methylases K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 298.0
WH2_k127_2475286_7 Methyltransferase K00564 - 2.1.1.172 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002195 288.0
WH2_k127_2475286_8 Tetrapyrrole (Corrin/Porphyrin) Methylases K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009416 284.0
WH2_k127_2475286_9 reductase K05895 - 1.3.1.106,1.3.1.54 0.00000000000000000000000000000000000000000000000000000000000001242 223.0
WH2_k127_2487029_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 531.0
WH2_k127_2487029_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 403.0
WH2_k127_2487029_10 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000002271 156.0
WH2_k127_2487029_11 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000004338 87.0
WH2_k127_2487029_2 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 387.0
WH2_k127_2487029_3 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 352.0
WH2_k127_2487029_4 COG2202 FOG PAS PAC domain K03406,K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 345.0
WH2_k127_2487029_5 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 307.0
WH2_k127_2487029_6 Protein of unknown function (DUF938) - - - 0.000000000000000000000000000000000000000000000000000000000000003353 224.0
WH2_k127_2487029_7 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000002558 205.0
WH2_k127_2487029_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000002611 211.0
WH2_k127_2487029_9 Flavodoxin-like fold K19784 - - 0.000000000000000000000000000000000000000000000000000002899 197.0
WH2_k127_2497928_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 542.0
WH2_k127_2497928_1 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 522.0
WH2_k127_2497928_10 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000004666 195.0
WH2_k127_2497928_11 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000005164 173.0
WH2_k127_2497928_12 protein conserved in bacteria K09796 - - 0.0000000000000000000000000000000001022 140.0
WH2_k127_2497928_13 nuclear chromosome segregation - - - 0.0000000000000000000000000000000009197 147.0
WH2_k127_2497928_14 Cytochrome c K08738 - - 0.0000000000000000000000000000001082 129.0
WH2_k127_2497928_15 PAS domain - - - 0.0000000000000000000000001775 111.0
WH2_k127_2497928_16 Outer membrane protein beta-barrel domain - - - 0.000000000006152 76.0
WH2_k127_2497928_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 511.0
WH2_k127_2497928_3 carnitine dehydratase K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 494.0
WH2_k127_2497928_4 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 466.0
WH2_k127_2497928_5 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 427.0
WH2_k127_2497928_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 404.0
WH2_k127_2497928_7 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 359.0
WH2_k127_2497928_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000844 233.0
WH2_k127_2497928_9 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000287 205.0
WH2_k127_2508104_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 7.011e-244 764.0
WH2_k127_2508104_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 2.075e-225 706.0
WH2_k127_2508104_10 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000197 138.0
WH2_k127_2508104_11 polysaccharide deacetylase - - - 0.00000000000000000003361 100.0
WH2_k127_2508104_12 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000001953 73.0
WH2_k127_2508104_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 575.0
WH2_k127_2508104_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 552.0
WH2_k127_2508104_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 555.0
WH2_k127_2508104_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 539.0
WH2_k127_2508104_6 methyl-accepting chemotaxis K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 540.0
WH2_k127_2508104_7 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000007338 207.0
WH2_k127_2508104_8 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000635 193.0
WH2_k127_2508104_9 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000002286 179.0
WH2_k127_2578582_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 3.928e-198 630.0
WH2_k127_2578582_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 612.0
WH2_k127_2578582_10 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 317.0
WH2_k127_2578582_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000006789 207.0
WH2_k127_2578582_12 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000001139 204.0
WH2_k127_2578582_13 antibiotic catabolic process K13277,K20276 - - 0.0000000000000000000000000000000000000000000000000000002141 223.0
WH2_k127_2578582_14 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000009095 187.0
WH2_k127_2578582_15 YCII-related domain - - - 0.00000000000000000000000000000000000000000000001739 173.0
WH2_k127_2578582_16 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000003444 167.0
WH2_k127_2578582_17 Membrane-associated sensor, integral membrane domain - - - 0.00000000000000000000000000000000000000003734 158.0
WH2_k127_2578582_18 PFAM Haemolysin-type calcium-binding repeat - - - 0.0000000000000000002199 105.0
WH2_k127_2578582_19 transferase activity, transferring glycosyl groups K20276 - - 0.00000000244 72.0
WH2_k127_2578582_2 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 509.0
WH2_k127_2578582_20 COG4235 Cytochrome c biogenesis factor K02200 - - 0.0003703 43.0
WH2_k127_2578582_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 396.0
WH2_k127_2578582_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 345.0
WH2_k127_2578582_5 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 336.0
WH2_k127_2578582_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 341.0
WH2_k127_2578582_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 325.0
WH2_k127_2578582_8 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 322.0
WH2_k127_2578582_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 315.0
WH2_k127_2710295_0 COG2217 Cation transport ATPase K17686 - 3.6.3.54 1.633e-280 881.0
WH2_k127_2710295_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 578.0
WH2_k127_2710295_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 354.0
WH2_k127_2710295_11 ABC transporter substrate-binding protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 340.0
WH2_k127_2710295_12 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 336.0
WH2_k127_2710295_13 transcriptional regulator K07506 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 334.0
WH2_k127_2710295_14 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 323.0
WH2_k127_2710295_15 Binding-protein-dependent transport system inner membrane component K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 319.0
WH2_k127_2710295_16 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
WH2_k127_2710295_17 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K10831 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0006950,GO:0007154,GO:0008144,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010438,GO:0017076,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0035639,GO:0036094,GO:0042594,GO:0043167,GO:0043168,GO:0050896,GO:0051716,GO:0071496,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 313.0
WH2_k127_2710295_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 295.0
WH2_k127_2710295_19 Glycine D-amino acid oxidases (deaminating) K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 283.0
WH2_k127_2710295_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 565.0
WH2_k127_2710295_20 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004938 282.0
WH2_k127_2710295_21 ABC transporter (Permease K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007658 272.0
WH2_k127_2710295_22 sulfate ABC transporter K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001821 259.0
WH2_k127_2710295_23 FCD - - - 0.000000000000000000000000000000000000000000000000000000001885 209.0
WH2_k127_2710295_24 - - - - 0.00000000000000000000000000000000000000000000000000001751 211.0
WH2_k127_2710295_25 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000003762 180.0
WH2_k127_2710295_26 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000003106 174.0
WH2_k127_2710295_27 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000007102 169.0
WH2_k127_2710295_28 MarR family - - - 0.000000000000000000000000000000000000001255 151.0
WH2_k127_2710295_29 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000002639 99.0
WH2_k127_2710295_3 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 446.0
WH2_k127_2710295_30 Universal stress protein UspA - - - 0.00000000000000006798 94.0
WH2_k127_2710295_31 heavy metal transport detoxification protein K07213 - - 0.000000001028 62.0
WH2_k127_2710295_32 - - - - 0.0000002606 56.0
WH2_k127_2710295_4 NMT1/THI5 like K15551 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 426.0
WH2_k127_2710295_5 sulfate ABC transporter K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 405.0
WH2_k127_2710295_6 Taurine catabolism dioxygenase TauD, TfdA family K03119 GO:0000907,GO:0000908,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0044237,GO:0044248,GO:0044273,GO:0044424,GO:0044464,GO:0051213,GO:0055114 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 398.0
WH2_k127_2710295_7 PFAM Taurine catabolism dioxygenase TauD TfdA K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 403.0
WH2_k127_2710295_8 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 353.0
WH2_k127_2710295_9 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 351.0
WH2_k127_276364_0 Phosphopantetheine attachment site - - - 0.0 1874.0
WH2_k127_276364_1 Xanthine dehydrogenase K13482 - 1.17.1.4 8.294e-302 965.0
WH2_k127_276364_10 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 377.0
WH2_k127_276364_11 TOBE domain K02052,K11084 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 381.0
WH2_k127_276364_12 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 327.0
WH2_k127_276364_13 TIGRFAM phenylacetate-CoA oxygenase, PaaI subunit K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 319.0
WH2_k127_276364_14 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 300.0
WH2_k127_276364_15 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 296.0
WH2_k127_276364_16 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 288.0
WH2_k127_276364_17 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009219 280.0
WH2_k127_276364_19 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000002173 257.0
WH2_k127_276364_2 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704 2.3.3.9 7.721e-235 746.0
WH2_k127_276364_20 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000001397 244.0
WH2_k127_276364_21 Asp Glu Hydantoin racemase K01799 - 5.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000001615 246.0
WH2_k127_276364_22 Iron-sulfur cluster assembly protein K02612 - - 0.000000000000000000000000000000000000000000000000000001792 197.0
WH2_k127_276364_23 FCD - - - 0.000000000000000000000000000000000000000000000008888 181.0
WH2_k127_276364_24 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000006747 175.0
WH2_k127_276364_25 Phenylacetic acid degradation B K02610 - - 0.000000000000000000000000000000000000004098 147.0
WH2_k127_276364_26 Domain of unknown function (DUF1971) - - - 0.00000000000000000000000000000004977 138.0
WH2_k127_276364_27 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.000000000000000000000000006229 114.0
WH2_k127_276364_28 allantoin biosynthetic process K13485 - 4.1.1.97 0.0000000000000000003925 100.0
WH2_k127_276364_29 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000000000002483 76.0
WH2_k127_276364_3 Amidohydrolase family - - - 1.891e-229 729.0
WH2_k127_276364_4 Phenylacetate-CoA oxygenase K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 552.0
WH2_k127_276364_5 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 483.0
WH2_k127_276364_6 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 479.0
WH2_k127_276364_7 Oxidoreductase NAD-binding domain K02613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 390.0
WH2_k127_276364_8 polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 378.0
WH2_k127_276364_9 Alternative oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 387.0
WH2_k127_2787568_0 transport system, permease component K02037 - - 2.701e-274 864.0
WH2_k127_2787568_1 phosphate transport system K02038 - - 3.31e-228 721.0
WH2_k127_2787568_10 Multicopper oxidase - - - 0.0000000000000000137 81.0
WH2_k127_2787568_11 Aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 0.000007783 52.0
WH2_k127_2787568_2 Alcohol dehydrogenase GroES-like domain K00148 - 1.2.1.46 2.812e-219 685.0
WH2_k127_2787568_3 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 458.0
WH2_k127_2787568_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 439.0
WH2_k127_2787568_5 DUF1338 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 403.0
WH2_k127_2787568_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 361.0
WH2_k127_2787568_7 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 355.0
WH2_k127_2787568_8 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 336.0
WH2_k127_2787568_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 294.0
WH2_k127_2819163_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1536.0
WH2_k127_2819163_1 ABC-type multidrug transport system ATPase and permease K06147,K18893 - - 2.808e-265 829.0
WH2_k127_2819163_10 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000002017 160.0
WH2_k127_2819163_11 cheY-homologous receiver domain - - - 0.0000000000000000000000000676 117.0
WH2_k127_2819163_12 Modulates RecA activity K03565 - - 0.000000000000000000000002147 118.0
WH2_k127_2819163_13 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000006169 96.0
WH2_k127_2819163_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 1.336e-219 690.0
WH2_k127_2819163_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 530.0
WH2_k127_2819163_4 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 465.0
WH2_k127_2819163_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 326.0
WH2_k127_2819163_6 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000436 160.0
WH2_k127_2819163_7 diguanylate cyclase - - - 0.0000000000000000000000000000000000000005041 165.0
WH2_k127_2819163_8 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000127 156.0
WH2_k127_2819163_9 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000003512 152.0
WH2_k127_2885295_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.0 1149.0
WH2_k127_2885295_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 2.835e-231 728.0
WH2_k127_2885295_10 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 319.0
WH2_k127_2885295_11 transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000105 279.0
WH2_k127_2885295_12 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001951 265.0
WH2_k127_2885295_13 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002232 254.0
WH2_k127_2885295_14 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000006197 245.0
WH2_k127_2885295_15 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000001258 225.0
WH2_k127_2885295_16 transporter component K07112 - - 0.000000000000000000000000000000000000000000000000000000000144 205.0
WH2_k127_2885295_17 transporter component K07112 - - 0.0000000000000000000000000000000000000000000000000001358 190.0
WH2_k127_2885295_18 serine-type endopeptidase activity K01312 - 3.4.21.4 0.0000000000000000000000000000000000000000000000001873 196.0
WH2_k127_2885295_19 transcriptional regulator - - - 0.00000000000000000000000000000000000000002745 159.0
WH2_k127_2885295_2 Probable molybdopterin binding domain K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 598.0
WH2_k127_2885295_20 PFAM regulatory protein ArsR K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000008016 148.0
WH2_k127_2885295_21 XdhC and CoxI family - - - 0.0000000000000000000000000000000000002134 158.0
WH2_k127_2885295_22 ligase activity - - - 0.00000000000000000000000000000003115 141.0
WH2_k127_2885295_23 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.000000000000000000000000000009143 123.0
WH2_k127_2885295_24 bleomycin resistance protein - - - 0.00000000000000000000002617 104.0
WH2_k127_2885295_25 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000146 102.0
WH2_k127_2885295_26 Phage-associated protein - - - 0.0000000002906 70.0
WH2_k127_2885295_27 Sel1 domain protein repeat-containing protein K07126 - - 0.00008185 48.0
WH2_k127_2885295_3 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 533.0
WH2_k127_2885295_4 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 472.0
WH2_k127_2885295_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 459.0
WH2_k127_2885295_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 394.0
WH2_k127_2885295_7 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 386.0
WH2_k127_2885295_8 Protein of unknown function (DUF3419) K13622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 381.0
WH2_k127_2885295_9 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 337.0
WH2_k127_2907547_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 1.029e-228 734.0
WH2_k127_2907547_1 Alkaline phosphatase homologues K01077 - 3.1.3.1 7.18e-218 691.0
WH2_k127_2907547_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 442.0
WH2_k127_2907547_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 354.0
WH2_k127_2907547_4 ABC-type Fe3 transport system, periplasmic K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 307.0
WH2_k127_2907547_5 Carboxylesterase family K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009218 274.0
WH2_k127_2907547_6 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000003173 224.0
WH2_k127_2907547_7 - - - - 0.0000000000000000000000000000000000000000002188 166.0
WH2_k127_2931248_0 CoA-transferase family III - - - 6.74e-240 747.0
WH2_k127_2931248_1 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 4.26e-220 698.0
WH2_k127_2931248_10 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 568.0
WH2_k127_2931248_11 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 454.0
WH2_k127_2931248_12 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 364.0
WH2_k127_2931248_13 racemase activity, acting on amino acids and derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 356.0
WH2_k127_2931248_14 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 299.0
WH2_k127_2931248_15 haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 297.0
WH2_k127_2931248_16 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 299.0
WH2_k127_2931248_17 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 294.0
WH2_k127_2931248_18 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 286.0
WH2_k127_2931248_19 ANTAR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003237 281.0
WH2_k127_2931248_2 Alkyl sulfatase dimerisation - - - 8.201e-206 656.0
WH2_k127_2931248_20 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000228 280.0
WH2_k127_2931248_21 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000226 268.0
WH2_k127_2931248_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005461 233.0
WH2_k127_2931248_23 membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000003389 220.0
WH2_k127_2931248_24 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000006762 219.0
WH2_k127_2931248_25 AraC-binding-like domain - - - 0.000000000000000000000000000000000000000000000000000000606 205.0
WH2_k127_2931248_26 - - - - 0.000000000000000000000000000000004838 146.0
WH2_k127_2931248_27 cheY-homologous receiver domain - - - 0.00000000000000000000000000000001435 130.0
WH2_k127_2931248_28 Anti-sigma factor K20148 - 1.13.11.50 0.000000000000000000000000001299 117.0
WH2_k127_2931248_29 transcriptional regulator K22295 - - 0.00000000000000000000003458 108.0
WH2_k127_2931248_3 Major facilitator superfamily K03446 - - 6.049e-195 637.0
WH2_k127_2931248_30 Domain of unknown function (DUF1835) - - - 0.0000000000000000000005181 108.0
WH2_k127_2931248_31 Belongs to the Dps family K04047 - - 0.000000000000002147 80.0
WH2_k127_2931248_32 Ferritin-like domain K04047 - - 0.0000000008955 64.0
WH2_k127_2931248_34 transcriptional regulator - - - 0.00000005165 62.0
WH2_k127_2931248_36 Ferritin-like domain K04047 - - 0.0000179 51.0
WH2_k127_2931248_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 610.0
WH2_k127_2931248_5 PFAM ABC transporter K02471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 618.0
WH2_k127_2931248_6 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 602.0
WH2_k127_2931248_7 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 614.0
WH2_k127_2931248_8 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 590.0
WH2_k127_2931248_9 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 584.0
WH2_k127_2969832_0 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 332.0
WH2_k127_2969832_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001918 277.0
WH2_k127_2969832_2 Cell division protein K09811 - - 0.00000000000000000000000000000000000000000000000000000000001915 217.0
WH2_k127_2969832_3 CBS domain - - - 0.0000000000000000000000000000000000000000000000000009397 190.0
WH2_k127_2969832_4 DUF218 domain - - - 0.00000000000000000000000000000000000000000000008588 177.0
WH2_k127_2969832_5 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000002782 152.0
WH2_k127_2969832_6 SnoaL-like domain - - - 0.00000000000000000000000002963 117.0
WH2_k127_2969832_7 zinc-ribbon domain - - - 0.0000000003963 63.0
WH2_k127_3003479_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 8.131e-304 942.0
WH2_k127_3003479_1 AMP-binding enzyme C-terminal domain K00666 - - 2.578e-241 771.0
WH2_k127_3003479_10 Protein of unknown function (DUF2390) - - - 0.0000000000000000001984 94.0
WH2_k127_3003479_11 META domain K09914 - - 0.0000000000000000002604 92.0
WH2_k127_3003479_12 Protein of unknown function (DUF465) - - - 0.00000000001149 76.0
WH2_k127_3003479_13 Dehydratase family - - - 0.00000003119 61.0
WH2_k127_3003479_14 Protein of unknown function (DUF465) - - - 0.000009961 56.0
WH2_k127_3003479_2 Acyl-CoA synthetase (NDP forming) K09181 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 - 6.306e-236 759.0
WH2_k127_3003479_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 614.0
WH2_k127_3003479_4 reductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 473.0
WH2_k127_3003479_5 Phenylalanine-4-hydroxylase K00500 GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016714,GO:0055114 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 447.0
WH2_k127_3003479_6 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 293.0
WH2_k127_3003479_7 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000004313 263.0
WH2_k127_3003479_8 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003592 231.0
WH2_k127_3003479_9 AsnC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000002803 166.0
WH2_k127_3063067_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.0 1359.0
WH2_k127_3063067_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07789 - - 0.0 1335.0
WH2_k127_3063067_10 - - - - 0.0000000000000000000764 93.0
WH2_k127_3063067_11 Polysaccharide biosynthesis/export protein - - - 0.0000000000000003165 87.0
WH2_k127_3063067_2 PFAM lipopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 594.0
WH2_k127_3063067_3 COG2148 Sugar transferases involved in lipopolysaccharide synthesis K03606,K20997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 527.0
WH2_k127_3063067_4 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 439.0
WH2_k127_3063067_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 425.0
WH2_k127_3063067_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 424.0
WH2_k127_3063067_7 Glycosyl hydrolases family 18 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 340.0
WH2_k127_3063067_8 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004698 237.0
WH2_k127_3063067_9 Methyltransferase domain - - - 0.00000000000000000000000000000000000000003752 166.0
WH2_k127_3069228_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 2.676e-265 844.0
WH2_k127_3069228_1 Alkaline phosphatase homologues K01077 - 3.1.3.1 2.183e-200 640.0
WH2_k127_3069228_10 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 417.0
WH2_k127_3069228_11 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 415.0
WH2_k127_3069228_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 390.0
WH2_k127_3069228_13 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 386.0
WH2_k127_3069228_14 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 370.0
WH2_k127_3069228_15 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 358.0
WH2_k127_3069228_16 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 349.0
WH2_k127_3069228_17 alpha/beta hydrolase fold K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 357.0
WH2_k127_3069228_18 3-beta hydroxysteroid dehydrogenase/isomerase family K19997 - 5.1.3.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 358.0
WH2_k127_3069228_19 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 317.0
WH2_k127_3069228_2 Belongs to the thiolase family K00626 - 2.3.1.9 1.447e-199 631.0
WH2_k127_3069228_20 AraC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 323.0
WH2_k127_3069228_21 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 314.0
WH2_k127_3069228_22 ABC transporter K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 306.0
WH2_k127_3069228_23 enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 314.0
WH2_k127_3069228_24 Inhibitor of apoptosis-promoting Bax1 K06890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001647 257.0
WH2_k127_3069228_25 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006929 268.0
WH2_k127_3069228_26 Polyhydroxyalkanoate synthesis repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000001597 241.0
WH2_k127_3069228_27 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000111 232.0
WH2_k127_3069228_28 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000005796 223.0
WH2_k127_3069228_29 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000001876 226.0
WH2_k127_3069228_3 AMP-binding enzyme C-terminal domain - - - 6.116e-197 631.0
WH2_k127_3069228_30 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000002217 218.0
WH2_k127_3069228_31 PFAM regulatory protein ArsR - - - 0.00000000000000000000000000000000000000000000000000000000006274 206.0
WH2_k127_3069228_32 LysR substrate binding domain K03566 - - 0.00000000000000000000000000000000000000000000000000000001244 223.0
WH2_k127_3069228_33 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000006385 195.0
WH2_k127_3069228_34 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000003117 196.0
WH2_k127_3069228_35 - - - - 0.0000000000000000000000000000000000000002708 153.0
WH2_k127_3069228_36 YCII-related domain - - - 0.00000000000000000000000000000000000006892 146.0
WH2_k127_3069228_37 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000008473 143.0
WH2_k127_3069228_38 DSBA-like thioredoxin domain K07396 - - 0.000000000000000000000000000000000002623 145.0
WH2_k127_3069228_39 - - - - 0.00000000000000000000000000000000000381 146.0
WH2_k127_3069228_4 Flavin-binding monooxygenase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 536.0
WH2_k127_3069228_40 UPF0391 membrane protein - - - 0.0000000000001519 71.0
WH2_k127_3069228_41 protein conserved in bacteria K09914 - - 0.0000000000002515 82.0
WH2_k127_3069228_42 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.00000004351 60.0
WH2_k127_3069228_5 inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 519.0
WH2_k127_3069228_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 500.0
WH2_k127_3069228_7 Major facilitator superfamily K18552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 491.0
WH2_k127_3069228_8 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 440.0
WH2_k127_3069228_9 Belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 422.0
WH2_k127_3098292_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 6.805e-211 713.0
WH2_k127_3098292_1 Surface antigen K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 544.0
WH2_k127_3098292_10 Domain of unknown function (DUF697) K06883,K08990 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000001006 165.0
WH2_k127_3098292_11 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000002324 115.0
WH2_k127_3098292_12 homolog of the cytoplasmic domain of flagellar protein FhlB K04061 - - 0.000000000000000000000005872 106.0
WH2_k127_3098292_13 Role in flagellar biosynthesis K02420 - - 0.000000000000000000006971 97.0
WH2_k127_3098292_14 Flagellar biosynthesis protein, FliO K02418 - - 0.00000000000000002605 86.0
WH2_k127_3098292_15 Flagellar hook-basal body K02408 - - 0.00000000000000441 78.0
WH2_k127_3098292_2 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 455.0
WH2_k127_3098292_3 YcjX-like family, DUF463 K06918 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 407.0
WH2_k127_3098292_4 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 407.0
WH2_k127_3098292_5 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 288.0
WH2_k127_3098292_6 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007929 279.0
WH2_k127_3098292_7 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000003152 223.0
WH2_k127_3098292_8 Bacterial export proteins, family 1 K02421 - - 0.000000000000000000000000000000000000000000000000000002881 205.0
WH2_k127_3098292_9 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000000000000567 169.0
WH2_k127_3103519_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1215.0
WH2_k127_3103519_1 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 509.0
WH2_k127_3103519_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000002048 235.0
WH2_k127_3103519_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000002162 164.0
WH2_k127_3103519_4 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000001212 143.0
WH2_k127_3119872_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 505.0
WH2_k127_3119872_1 TIGRFAM TIGR03032 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 394.0
WH2_k127_3119872_2 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 386.0
WH2_k127_3119872_3 Type II secretory pathway, component PulD K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 389.0
WH2_k127_3119872_4 type II secretion system protein K K02460 - - 0.000000000000000000000000000000001055 145.0
WH2_k127_3119872_5 - - - - 0.000000000000000000000000000001897 134.0
WH2_k127_3119872_6 Prokaryotic N-terminal methylation motif K02458 - - 0.000000000000000000696 93.0
WH2_k127_3119872_7 GcrA cell cycle regulator K13583 - - 0.0000000000000009243 79.0
WH2_k127_3119872_9 Prokaryotic N-terminal methylation motif K02459 - - 0.00005745 53.0
WH2_k127_3146213_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 3.185e-236 757.0
WH2_k127_3146213_1 FMN-dependent alpha-hydroxy acid dehydrogenase K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 584.0
WH2_k127_3146213_2 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 579.0
WH2_k127_3146213_3 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 575.0
WH2_k127_3146213_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 516.0
WH2_k127_3146213_5 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 378.0
WH2_k127_3146213_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 302.0
WH2_k127_3146213_7 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000001154 136.0
WH2_k127_3146213_8 FCD K05799,K14348 - - 0.0003019 53.0
WH2_k127_320456_0 mechanosensitive ion channel K22044 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 350.0
WH2_k127_320456_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 321.0
WH2_k127_320456_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 315.0
WH2_k127_320456_3 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000004118 193.0
WH2_k127_320456_4 Protein of unknown function (DUF3574) - - - 0.000000000000000000000001525 111.0
WH2_k127_320456_5 P-aminobenzoate N-oxygenase AurF - - - 0.000267 51.0
WH2_k127_3218872_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1411.0
WH2_k127_3218872_1 GTP-binding protein TypA K06207 - - 3.301e-306 947.0
WH2_k127_3218872_10 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 482.0
WH2_k127_3218872_11 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009834 478.0
WH2_k127_3218872_12 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 450.0
WH2_k127_3218872_13 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 401.0
WH2_k127_3218872_14 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 398.0
WH2_k127_3218872_15 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 395.0
WH2_k127_3218872_16 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 387.0
WH2_k127_3218872_17 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 363.0
WH2_k127_3218872_18 Shikimate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 342.0
WH2_k127_3218872_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 310.0
WH2_k127_3218872_2 Transport of potassium into the cell K03549 - - 1.906e-243 769.0
WH2_k127_3218872_20 Enoyl-CoA hydratase/isomerase K20036 - 4.2.1.155 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 312.0
WH2_k127_3218872_21 Alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 309.0
WH2_k127_3218872_22 AAA domain, putative AbiEii toxin, Type IV TA system K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002425 304.0
WH2_k127_3218872_23 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004772 308.0
WH2_k127_3218872_24 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002345 297.0
WH2_k127_3218872_25 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001945 276.0
WH2_k127_3218872_26 Acts on guanine, xanthine and to a lesser extent hypoxanthine K00769 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000000000000000000005493 248.0
WH2_k127_3218872_27 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002335 250.0
WH2_k127_3218872_28 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001477 248.0
WH2_k127_3218872_29 Belongs to the hyi family K22131 - 5.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000004728 235.0
WH2_k127_3218872_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 4.298e-223 705.0
WH2_k127_3218872_30 - - - - 0.000000000000000000000000000000000000000000000000000000000002892 216.0
WH2_k127_3218872_31 PFAM Mammalian cell entry related K02067 - - 0.00000000000000000000000000000000000000000000000000000000009884 216.0
WH2_k127_3218872_32 Protein of unknown function DUF115 - - - 0.0000000000000000000000000000000000000000000000000003704 203.0
WH2_k127_3218872_33 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000001089 196.0
WH2_k127_3218872_34 - - - - 0.000000000000000000000000000000000000000000000000002835 195.0
WH2_k127_3218872_35 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000001187 190.0
WH2_k127_3218872_36 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000005087 186.0
WH2_k127_3218872_37 Flavodoxin - - - 0.000000000000000000000000000000000000000000000002878 178.0
WH2_k127_3218872_38 - - - - 0.000000000000000000000000000000000000000000000003123 182.0
WH2_k127_3218872_39 Protein of unknown function DUF115 - - - 0.00000000000000000000000000000000000000000000001012 194.0
WH2_k127_3218872_4 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 1.287e-213 679.0
WH2_k127_3218872_40 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000000000000000001386 181.0
WH2_k127_3218872_41 NnrU protein - - - 0.00000000000000000000000000000000000000000000002511 182.0
WH2_k127_3218872_42 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000002183 147.0
WH2_k127_3218872_43 - - - - 0.0000000000000000000000000002713 117.0
WH2_k127_3218872_44 Signal transduction histidine kinase - - - 0.00000000000000000000000878 113.0
WH2_k127_3218872_45 Protein conserved in bacteria K01002 - 2.7.8.20 0.000000000000000006871 96.0
WH2_k127_3218872_46 - - - - 0.000002449 57.0
WH2_k127_3218872_5 Receptor K16087,K16089,K16092 - - 1.658e-212 681.0
WH2_k127_3218872_6 Psort location Cytoplasmic, score 7.50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 534.0
WH2_k127_3218872_7 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 516.0
WH2_k127_3218872_8 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 488.0
WH2_k127_3218872_9 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 497.0
WH2_k127_3268046_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 6.37e-322 993.0
WH2_k127_3268046_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 569.0
WH2_k127_3268046_2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 437.0
WH2_k127_3268046_3 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 356.0
WH2_k127_3268046_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000001038 249.0
WH2_k127_3268046_5 Apolipoprotein A1/A4/E domain - - - 0.0000000000000000000000000000005611 142.0
WH2_k127_334010_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1207.0
WH2_k127_334010_1 COG1879 ABC-type sugar transport system periplasmic component K10439,K11930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 535.0
WH2_k127_334010_10 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 356.0
WH2_k127_334010_11 EamA-like transporter family K15269 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 302.0
WH2_k127_334010_2 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 527.0
WH2_k127_334010_3 Pfam:AHS1 K01941 - 6.3.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 485.0
WH2_k127_334010_4 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 464.0
WH2_k127_334010_5 response to pH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 426.0
WH2_k127_334010_6 Carboxyltransferase domain, subdomain A and B K01457,K01941 - 3.5.1.54,6.3.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 417.0
WH2_k127_334010_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 415.0
WH2_k127_334010_8 Transport Permease Protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 391.0
WH2_k127_334010_9 Branched-chain amino acid transport system / permease component K10440,K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 385.0
WH2_k127_3359569_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05577 - 1.6.5.3 8.959e-235 736.0
WH2_k127_3359569_1 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 3.86e-200 641.0
WH2_k127_3359569_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 585.0
WH2_k127_3359569_3 LysR substrate binding domain K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 458.0
WH2_k127_3359569_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 389.0
WH2_k127_3359569_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 320.0
WH2_k127_3359569_6 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008551 270.0
WH2_k127_3359569_7 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000007752 160.0
WH2_k127_3359569_8 Initiation factor 2 subunit family K08963 - 5.3.1.23 0.0004893 51.0
WH2_k127_3424202_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 605.0
WH2_k127_3424202_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 499.0
WH2_k127_3424202_10 branched-chain amino acid permease (azaleucine resistance) - - - 0.00000000000000000000000000000000000000000000000000005447 195.0
WH2_k127_3424202_11 chorismate mutase - - - 0.000000000000000000000000000000000000000000003353 177.0
WH2_k127_3424202_12 Autoinducer binding domain K07782,K20540 - - 0.00000000000000000000000001301 119.0
WH2_k127_3424202_13 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000004718 112.0
WH2_k127_3424202_14 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000003503 91.0
WH2_k127_3424202_16 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.000000001141 64.0
WH2_k127_3424202_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 450.0
WH2_k127_3424202_3 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 404.0
WH2_k127_3424202_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 336.0
WH2_k127_3424202_5 methionine biosynthesis protein (MetW) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001765 258.0
WH2_k127_3424202_6 ABC transporter K01996,K11958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000304 256.0
WH2_k127_3424202_7 Beta-lactamase class C - - - 0.000000000000000000000000000000000000000000000000000000000000000000005833 248.0
WH2_k127_3424202_8 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008653 239.0
WH2_k127_3424202_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000166 210.0
WH2_k127_3461358_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 604.0
WH2_k127_3461358_1 methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 474.0
WH2_k127_3461358_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 404.0
WH2_k127_3461358_3 N-acetyltransferase K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000000000000409 236.0
WH2_k127_3461358_4 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000003208 243.0
WH2_k127_3461358_5 transcriptional regulator - - - 0.000000000000000000000001741 105.0
WH2_k127_3488104_0 FAD binding domain K05712 - 1.14.13.127 6.005e-248 774.0
WH2_k127_3488104_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 4.829e-241 758.0
WH2_k127_3488104_10 Protein of unknown function (DUF2783) - - - 0.00000000000000000000003473 100.0
WH2_k127_3488104_11 ATPases associated with a variety of cellular activities K02003 - - 0.0000000008966 61.0
WH2_k127_3488104_2 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 532.0
WH2_k127_3488104_3 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 418.0
WH2_k127_3488104_4 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 394.0
WH2_k127_3488104_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 362.0
WH2_k127_3488104_6 Bacterial transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 295.0
WH2_k127_3488104_7 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000005927 231.0
WH2_k127_3488104_8 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000007692 239.0
WH2_k127_3488104_9 - - - - 0.000000000000000000000000001218 122.0
WH2_k127_3510005_0 Glycine cleavage T-protein C-terminal barrel domain K00302,K22086 - 1.5.3.1,1.5.99.5 0.0 1419.0
WH2_k127_3510005_1 FAD dependent oxidoreductase K00303,K22084 - 1.5.3.1,1.5.99.5 2.556e-248 770.0
WH2_k127_3510005_10 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 498.0
WH2_k127_3510005_11 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 488.0
WH2_k127_3510005_12 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 471.0
WH2_k127_3510005_13 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 452.0
WH2_k127_3510005_14 metal-dependent hydrolase involved in phosphonate metabolism K06162 - 3.6.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 458.0
WH2_k127_3510005_15 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 441.0
WH2_k127_3510005_16 phosphonate C-P lyase system protein PhnK K05781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 435.0
WH2_k127_3510005_17 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 416.0
WH2_k127_3510005_18 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 419.0
WH2_k127_3510005_19 Formyl transferase K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 415.0
WH2_k127_3510005_2 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 4.604e-232 730.0
WH2_k127_3510005_20 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 393.0
WH2_k127_3510005_21 TIGRFAM cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 392.0
WH2_k127_3510005_22 Oxidoreductase NAD-binding domain K02613,K05916,K07006 - 1.14.12.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 385.0
WH2_k127_3510005_23 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 362.0
WH2_k127_3510005_24 COG3454 Metal-dependent hydrolase involved in phosphonate metabolism K06162 - 3.6.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 370.0
WH2_k127_3510005_25 (ABC transporter), ATP-binding K05780 - 2.7.8.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 356.0
WH2_k127_3510005_26 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 345.0
WH2_k127_3510005_27 UTRA K02043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 334.0
WH2_k127_3510005_28 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 332.0
WH2_k127_3510005_29 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 330.0
WH2_k127_3510005_3 Ring hydroxylating alpha subunit (catalytic domain) K00479,K05549,K05708,K14748,K16319 - 1.14.12.1,1.14.12.10,1.14.12.19 2.552e-227 714.0
WH2_k127_3510005_30 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 314.0
WH2_k127_3510005_31 Substrate binding domain of ABC-type glycine betaine transport system K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 308.0
WH2_k127_3510005_32 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 287.0
WH2_k127_3510005_33 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007314 266.0
WH2_k127_3510005_34 FAD-NAD(P)-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005613 261.0
WH2_k127_3510005_35 Transcriptional regulator, TetR, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000004138 227.0
WH2_k127_3510005_36 Bacterial phosphonate metabolism protein (PhnH) K06165 - 2.7.8.37 0.00000000000000000000000000000000000000000000000000000000000005399 226.0
WH2_k127_3510005_37 PFAM BLUF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001115 207.0
WH2_k127_3510005_38 Protein of unknown function (DUF1045) - - - 0.0000000000000000000000000000000000000000000000000001699 194.0
WH2_k127_3510005_39 Phosphonate metabolism protein PhnG K06166 - 2.7.8.37 0.000000000000000000000000000000000000000000000002114 177.0
WH2_k127_3510005_4 AMP-binding enzyme K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 616.0
WH2_k127_3510005_40 Sarcosine oxidase, gamma subunit K00305,K22087 - 1.5.3.1,1.5.99.5 0.000000000000000000000000000000000000000009757 162.0
WH2_k127_3510005_41 Transcriptional regulator - - - 0.0000000000000000000000000000000004132 141.0
WH2_k127_3510005_42 Biotin carboxylase C-terminal domain - - - 0.00000000000000000000000000000008933 126.0
WH2_k127_3510005_43 Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) K05774 - 2.7.4.23 0.0000000000000000000000000000001708 127.0
WH2_k127_3510005_44 Sarcosine oxidase, delta subunit K00304,K22085 - 1.5.3.1,1.5.99.5 0.000000000000000000000000000001045 123.0
WH2_k127_3510005_45 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity K18437 - 3.1.4.53 0.00007176 54.0
WH2_k127_3510005_5 ABC transporter K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 606.0
WH2_k127_3510005_6 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 601.0
WH2_k127_3510005_7 phosphonate metabolism K06164 - 2.7.8.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 567.0
WH2_k127_3510005_8 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 570.0
WH2_k127_3510005_9 Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose K06163 - 4.7.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 513.0
WH2_k127_3522754_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1205.0
WH2_k127_3522754_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 7.497e-247 770.0
WH2_k127_3522754_10 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 423.0
WH2_k127_3522754_11 DNA polymerase III subunit delta K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 396.0
WH2_k127_3522754_12 Lytic murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 372.0
WH2_k127_3522754_13 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 346.0
WH2_k127_3522754_14 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 342.0
WH2_k127_3522754_15 TIGRFAM MazG family protein K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 338.0
WH2_k127_3522754_16 transcriptional regulator K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 329.0
WH2_k127_3522754_17 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 320.0
WH2_k127_3522754_18 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 318.0
WH2_k127_3522754_19 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 310.0
WH2_k127_3522754_2 ABC transporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 593.0
WH2_k127_3522754_20 transferase activity, transferring glycosyl groups K00754,K13684 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035250,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 318.0
WH2_k127_3522754_21 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 314.0
WH2_k127_3522754_22 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 302.0
WH2_k127_3522754_23 transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 317.0
WH2_k127_3522754_24 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 286.0
WH2_k127_3522754_25 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000191 281.0
WH2_k127_3522754_26 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001765 270.0
WH2_k127_3522754_27 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001292 268.0
WH2_k127_3522754_28 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002454 256.0
WH2_k127_3522754_29 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001748 250.0
WH2_k127_3522754_3 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 579.0
WH2_k127_3522754_30 Mitochondrial fission ELM1 K07276 - - 0.00000000000000000000000000000000000000000000000000000000000000000001057 245.0
WH2_k127_3522754_31 Phosphorylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000009686 241.0
WH2_k127_3522754_32 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000006095 229.0
WH2_k127_3522754_33 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000001458 232.0
WH2_k127_3522754_34 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000001004 229.0
WH2_k127_3522754_35 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K15599 - - 0.00000000000000000000000000000000000000000000000000000006342 213.0
WH2_k127_3522754_36 Phage Tail Collar Domain - - - 0.000000000000000000000000000000000000000000000000002694 188.0
WH2_k127_3522754_37 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000001283 185.0
WH2_k127_3522754_38 Microcystin-dependent protein - - - 0.00000000000000000000000000000000000000002743 160.0
WH2_k127_3522754_39 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000000000007588 157.0
WH2_k127_3522754_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 556.0
WH2_k127_3522754_40 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000000000000009305 154.0
WH2_k127_3522754_41 FR47-like protein - - - 0.000000000000000000000002749 111.0
WH2_k127_3522754_42 polysaccharide biosynthetic process K03183,K15256 - 2.1.1.163,2.1.1.201 0.00000000000000000004557 100.0
WH2_k127_3522754_43 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000003718 90.0
WH2_k127_3522754_44 Protein of unknown function DUF126 - - - 0.000000000000135 72.0
WH2_k127_3522754_45 - - - - 0.000000007652 67.0
WH2_k127_3522754_5 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 547.0
WH2_k127_3522754_6 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 536.0
WH2_k127_3522754_7 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 509.0
WH2_k127_3522754_8 Diguanylate cyclase K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 475.0
WH2_k127_3522754_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 439.0
WH2_k127_3544698_0 sarcosine oxidase, beta subunit K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 590.0
WH2_k127_3544698_1 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006807,GO:0008150,GO:0008152,GO:0008783,GO:0009058,GO:0016787,GO:0016810,GO:0016813,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097055,GO:1901160,GO:1901162,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 584.0
WH2_k127_3544698_10 COG1176 ABC-type spermidine putrescine transport system permease component I K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 407.0
WH2_k127_3544698_11 PFAM Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 410.0
WH2_k127_3544698_12 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006015 403.0
WH2_k127_3544698_13 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 400.0
WH2_k127_3544698_14 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008547 396.0
WH2_k127_3544698_15 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 372.0
WH2_k127_3544698_16 3-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 376.0
WH2_k127_3544698_17 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 348.0
WH2_k127_3544698_18 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 341.0
WH2_k127_3544698_19 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 336.0
WH2_k127_3544698_2 FAD dependent oxidoreductase K04755,K09471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 560.0
WH2_k127_3544698_20 Alkylated DNA repair protein K03919 - 1.14.11.33 0.00000000000000000000000000000000000000000000000000000000000000000000000004048 254.0
WH2_k127_3544698_21 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000002121 250.0
WH2_k127_3544698_22 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000004734 239.0
WH2_k127_3544698_23 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000001296 212.0
WH2_k127_3544698_24 Belongs to the GcvT family K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000002433 211.0
WH2_k127_3544698_25 COG1778 Low specificity phosphatase (HAD superfamily) K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000003611 169.0
WH2_k127_3544698_26 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000755 170.0
WH2_k127_3544698_27 Sarcosine oxidase delta subunit K00304 - 1.5.3.1 0.0000000000000000000000000000000000003174 142.0
WH2_k127_3544698_28 WHG domain - - - 0.000000000000000000000000000000006561 135.0
WH2_k127_3544698_29 nUDIX hydrolase - - - 0.00000000000000000000000006321 113.0
WH2_k127_3544698_3 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 541.0
WH2_k127_3544698_30 Bacterial PH domain - - - 0.00000000000000000000000007577 114.0
WH2_k127_3544698_4 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 486.0
WH2_k127_3544698_5 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 472.0
WH2_k127_3544698_6 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 444.0
WH2_k127_3544698_7 TOBE domain K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 438.0
WH2_k127_3544698_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 447.0
WH2_k127_3544698_9 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 415.0
WH2_k127_3571752_0 belongs to the aldehyde dehydrogenase family K00151 - 1.2.1.60 3.261e-253 803.0
WH2_k127_3571752_1 peptidase dimerisation domain protein - - - 1.068e-217 691.0
WH2_k127_3571752_10 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 439.0
WH2_k127_3571752_11 Class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 411.0
WH2_k127_3571752_12 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 395.0
WH2_k127_3571752_13 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 345.0
WH2_k127_3571752_14 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 323.0
WH2_k127_3571752_15 regulatory protein LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 317.0
WH2_k127_3571752_16 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001865 259.0
WH2_k127_3571752_17 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001102 267.0
WH2_k127_3571752_18 4-hydroxyphenylacetate degradation bifunctional isomerase decarboxylase K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000004183 246.0
WH2_k127_3571752_19 carbohydrate binding K07336 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002393 244.0
WH2_k127_3571752_2 PFAM extracellular solute-binding protein family 5 K02035 - - 3.891e-214 676.0
WH2_k127_3571752_20 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.00000000000000000000000000000000000000000000000000005734 196.0
WH2_k127_3571752_21 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000007428 155.0
WH2_k127_3571752_22 photosystem II stabilization - - - 0.00000000000000000000000000000000002106 146.0
WH2_k127_3571752_3 Domain of unknown function (DUF3369) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 549.0
WH2_k127_3571752_4 3,4-dihydroxyphenylacetate 2,3-dioxygenase K00455 - 1.13.11.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 506.0
WH2_k127_3571752_5 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 451.0
WH2_k127_3571752_6 ABC-type dipeptide oligopeptide nickel transport system, permease component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 433.0
WH2_k127_3571752_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 447.0
WH2_k127_3571752_8 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 438.0
WH2_k127_3571752_9 2-oxo-hepta-3-ene-1,7-dioic acid hydratase K01617,K02509 - 4.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 427.0
WH2_k127_3600552_0 Response regulator receiver - - - 0.0 1243.0
WH2_k127_3600552_1 Cysteine-rich domain - - - 6e-208 666.0
WH2_k127_3600552_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000004385 223.0
WH2_k127_3600552_11 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000003518 195.0
WH2_k127_3600552_12 protein conserved in bacteria K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000004642 164.0
WH2_k127_3600552_2 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 574.0
WH2_k127_3600552_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 556.0
WH2_k127_3600552_4 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 360.0
WH2_k127_3600552_5 oxidoreductase K09471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 302.0
WH2_k127_3600552_6 In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001495 278.0
WH2_k127_3600552_7 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005509 257.0
WH2_k127_3600552_8 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000001423 226.0
WH2_k127_3600552_9 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000002488 218.0
WH2_k127_3605465_0 membrane - - - 1.315e-240 764.0
WH2_k127_3605465_1 Aerotolerance regulator N-terminal - - - 1.474e-222 710.0
WH2_k127_3605465_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 371.0
WH2_k127_3605465_11 ATP-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 372.0
WH2_k127_3605465_12 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 360.0
WH2_k127_3605465_13 ABC-type sulfate transport system, permease component K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 349.0
WH2_k127_3605465_14 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 322.0
WH2_k127_3605465_15 Binding-protein-dependent transport system inner membrane component K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 319.0
WH2_k127_3605465_16 PFAM histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 331.0
WH2_k127_3605465_17 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 305.0
WH2_k127_3605465_18 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 307.0
WH2_k127_3605465_19 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001289 266.0
WH2_k127_3605465_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 548.0
WH2_k127_3605465_20 COG1956 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000000000000000000000000000007726 263.0
WH2_k127_3605465_21 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000008996 248.0
WH2_k127_3605465_22 Rhamnan synthesis protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000004641 243.0
WH2_k127_3605465_23 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000002987 229.0
WH2_k127_3605465_24 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000004416 223.0
WH2_k127_3605465_25 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000002392 232.0
WH2_k127_3605465_26 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000005104 222.0
WH2_k127_3605465_27 the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription K03088 - - 0.000000000000000000000000000000000000000000000000000000000491 207.0
WH2_k127_3605465_28 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000003571 204.0
WH2_k127_3605465_29 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000001195 186.0
WH2_k127_3605465_3 Periplasmic binding protein K02016 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 480.0
WH2_k127_3605465_30 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000001336 192.0
WH2_k127_3605465_31 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000004526 169.0
WH2_k127_3605465_32 Protein of unknown function with HXXEE motif - - - 0.0000000000000000000000000000000000000005208 164.0
WH2_k127_3605465_33 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000128 96.0
WH2_k127_3605465_34 - - - - 0.0000000000000002084 85.0
WH2_k127_3605465_35 GCN5-related N-acetyltransferase K03823 - 2.3.1.183 0.00000000008497 70.0
WH2_k127_3605465_4 Gkycosyl transferase family 4 group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 469.0
WH2_k127_3605465_5 TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 456.0
WH2_k127_3605465_6 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 437.0
WH2_k127_3605465_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 448.0
WH2_k127_3605465_8 methyl-accepting chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 423.0
WH2_k127_3605465_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 395.0
WH2_k127_3629840_0 SMART AAA ATPase K20530 - - 0.0 1604.0
WH2_k127_3629840_1 PFAM TrbL VirB6 plasmid conjugal transfer protein K07344 - - 9.836e-230 720.0
WH2_k127_3629840_10 LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 405.0
WH2_k127_3629840_11 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 393.0
WH2_k127_3629840_12 PFAM type II secretion system protein E K20527 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 379.0
WH2_k127_3629840_13 PFAM conjugation TrbI family protein K20533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 338.0
WH2_k127_3629840_14 Bacterial conjugation TrbI-like protein K20533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 345.0
WH2_k127_3629840_15 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 317.0
WH2_k127_3629840_16 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 315.0
WH2_k127_3629840_17 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 313.0
WH2_k127_3629840_18 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 306.0
WH2_k127_3629840_19 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007787 280.0
WH2_k127_3629840_2 Conjugal transfer protein trbG K20532 - - 3.121e-197 622.0
WH2_k127_3629840_20 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004675 255.0
WH2_k127_3629840_21 TIGRFAM P-type conjugative transfer ATPase TrbB K20527 - - 0.000000000000000000000000000000000000000000000000000000000000000000003415 237.0
WH2_k127_3629840_22 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000002023 215.0
WH2_k127_3629840_23 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000003136 214.0
WH2_k127_3629840_24 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000002074 226.0
WH2_k127_3629840_25 Type IV secretory pathway, VirB3-like protein K20529 - - 0.0000000000000000000000000000000000000000000000000000005688 203.0
WH2_k127_3629840_26 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000003855 191.0
WH2_k127_3629840_27 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000001565 192.0
WH2_k127_3629840_28 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000009621 173.0
WH2_k127_3629840_29 - - - - 0.000000000000000000000000000000000000000000006262 164.0
WH2_k127_3629840_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 482.0
WH2_k127_3629840_30 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000002355 153.0
WH2_k127_3629840_31 DNA-binding transcription factor activity K06075 - - 0.000000000000000000000000000000000000000715 166.0
WH2_k127_3629840_32 SnoaL-like domain K06893 - - 0.0000000000000000000000000000000001107 138.0
WH2_k127_3629840_33 conserved small protein - - - 0.000000000000000000000000000184 116.0
WH2_k127_3629840_34 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 0.0000000000000000000000000002515 128.0
WH2_k127_3629840_35 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000005707 102.0
WH2_k127_3629840_4 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 482.0
WH2_k127_3629840_5 Conjugal transfer protein K20531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 441.0
WH2_k127_3629840_6 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 443.0
WH2_k127_3629840_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 429.0
WH2_k127_3629840_8 COG0436 Aspartate tyrosine aromatic aminotransferase K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 434.0
WH2_k127_3629840_9 TIGRFAM P-type conjugative transfer protein TrbJ K20266 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 413.0
WH2_k127_3701642_0 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.0 1179.0
WH2_k127_3701642_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 5e-324 1025.0
WH2_k127_3701642_2 ABC transporter K02056 - 3.6.3.17 3.472e-270 840.0
WH2_k127_3701642_3 Glycine cleavage T-protein C-terminal barrel domain K00302,K22086 - 1.5.3.1,1.5.99.5 1.002e-245 771.0
WH2_k127_3701642_4 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 512.0
WH2_k127_3701642_5 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 481.0
WH2_k127_3701642_6 AraC family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 436.0
WH2_k127_3701642_7 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 321.0
WH2_k127_3701642_8 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001201 290.0
WH2_k127_3701642_9 Sarcosine oxidase, gamma subunit K00305,K22087 - 1.5.3.1,1.5.99.5 0.000000000000000000000001221 111.0
WH2_k127_3724989_0 AMP-binding enzyme K12508 - 6.2.1.34 6.895e-233 748.0
WH2_k127_3724989_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 585.0
WH2_k127_3724989_10 Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005619 274.0
WH2_k127_3724989_11 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000257 250.0
WH2_k127_3724989_12 Thioesterase-like superfamily K01075 - 3.1.2.23 0.00000000000000000000000000000000000000001806 156.0
WH2_k127_3724989_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 501.0
WH2_k127_3724989_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 449.0
WH2_k127_3724989_4 succinylglutamate desuccinylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 411.0
WH2_k127_3724989_5 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 368.0
WH2_k127_3724989_6 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K10021,K10025 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 353.0
WH2_k127_3724989_7 phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 344.0
WH2_k127_3724989_8 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 343.0
WH2_k127_3724989_9 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 323.0
WH2_k127_3729335_0 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.0 1738.0
WH2_k127_3729335_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1270.0
WH2_k127_3729335_10 DNA polymerase beta domain protein region K07075 - - 0.000000000000000000000000000000000004841 140.0
WH2_k127_3729335_11 PFAM PhnA protein K06193 - - 0.00000000000000000000000000000003389 126.0
WH2_k127_3729335_12 Protein of unknown function DUF86 - - - 0.0000000000000000000000000005583 115.0
WH2_k127_3729335_13 Domain of unknown function (DUF4167) - - - 0.0000000000000000000000002895 113.0
WH2_k127_3729335_14 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000004376 109.0
WH2_k127_3729335_15 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000004338 87.0
WH2_k127_3729335_16 type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00000000002992 75.0
WH2_k127_3729335_2 G8 domain - - - 0.0 1083.0
WH2_k127_3729335_3 Type I restriction-modification system methyltransferase subunit K03427 - 2.1.1.72 1.538e-289 893.0
WH2_k127_3729335_4 phosphate transporter K03306 - - 1.441e-222 701.0
WH2_k127_3729335_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.663e-199 628.0
WH2_k127_3729335_6 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 522.0
WH2_k127_3729335_7 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 473.0
WH2_k127_3729335_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000328 273.0
WH2_k127_3729335_9 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000001407 242.0
WH2_k127_3768092_0 E1-E2 ATPase K01534 - 3.6.3.3,3.6.3.5 0.0 1244.0
WH2_k127_3768092_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1036.0
WH2_k127_3768092_10 Domain of unknown function (DUF4214) - - - 0.000001041 62.0
WH2_k127_3768092_2 Phage tail sheath protein K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 339.0
WH2_k127_3768092_3 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000002457 229.0
WH2_k127_3768092_4 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000002935 188.0
WH2_k127_3768092_5 electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000002703 171.0
WH2_k127_3768092_6 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.0000000000000000000000000000000001846 141.0
WH2_k127_3768092_7 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000002015 132.0
WH2_k127_3768092_8 -acetyltransferase K03824 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000008713 87.0
WH2_k127_3768092_9 TerD domain K05795 - - 0.00000001304 59.0
WH2_k127_3793040_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 550.0
WH2_k127_3793040_1 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 381.0
WH2_k127_3793040_2 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 291.0
WH2_k127_3793040_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000107 269.0
WH2_k127_3793040_4 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005893 259.0
WH2_k127_3793040_5 - - - - 0.000000000000000000000000000000000000000000000002434 185.0
WH2_k127_3793040_6 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000002863 170.0
WH2_k127_3793040_7 - - - - 0.0000000000000000000000000007499 123.0
WH2_k127_3839323_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0 1108.0
WH2_k127_3839323_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 480.0
WH2_k127_3839323_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 457.0
WH2_k127_3839323_3 Acetyl xylan esterase (AXE1) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 314.0
WH2_k127_3839323_4 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000001222 139.0
WH2_k127_3839323_5 Methylmuconolactone methyl-isomerase - - - 0.0000000000000000000000000001223 133.0
WH2_k127_3839323_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000001013 94.0
WH2_k127_3839323_7 - - - - 0.000000007271 63.0
WH2_k127_3839323_8 - - - - 0.00000109 58.0
WH2_k127_3857180_0 Transcriptional accessory protein K06959 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.0 1157.0
WH2_k127_3857180_1 Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source K01505,K05396 - 3.5.99.7,4.4.1.15 2.219e-194 610.0
WH2_k127_3857180_10 Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000385 190.0
WH2_k127_3857180_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.0000000000000000000000000000000004004 141.0
WH2_k127_3857180_12 PIN domain - - - 0.0000000000000000000000000001074 119.0
WH2_k127_3857180_13 Protein of unknown function (DUF1272) K09984 - - 0.000000000000000000000000001159 118.0
WH2_k127_3857180_14 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000004844 109.0
WH2_k127_3857180_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 481.0
WH2_k127_3857180_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 451.0
WH2_k127_3857180_4 Flavodoxin-like fold K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 435.0
WH2_k127_3857180_5 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 353.0
WH2_k127_3857180_6 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 320.0
WH2_k127_3857180_7 FCD K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007817 257.0
WH2_k127_3857180_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000001161 240.0
WH2_k127_3857180_9 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000001531 199.0
WH2_k127_3875090_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1229.0
WH2_k127_3875090_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.005e-270 845.0
WH2_k127_3875090_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000005087 106.0
WH2_k127_3875090_11 Lipopolysaccharide-assembly K03643 - - 0.00000000424 64.0
WH2_k127_3875090_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 419.0
WH2_k127_3875090_3 Chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 371.0
WH2_k127_3875090_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 301.0
WH2_k127_3875090_5 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 291.0
WH2_k127_3875090_6 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000006188 234.0
WH2_k127_3875090_7 Domain of unknown function (DUF3576) - - - 0.000000000000000000000000000000000000000000008476 169.0
WH2_k127_3875090_8 Gram-negative porin K08720 - - 0.000000000000000000000000000000000000001741 156.0
WH2_k127_3883483_0 ABC-type dipeptide transport system periplasmic component K02035 - - 7.639e-277 859.0
WH2_k127_3883483_1 Xylose isomerase domain protein TIM barrel K00457 - 1.13.11.27 1.197e-232 736.0
WH2_k127_3883483_10 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 482.0
WH2_k127_3883483_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 475.0
WH2_k127_3883483_12 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 456.0
WH2_k127_3883483_13 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 454.0
WH2_k127_3883483_14 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 429.0
WH2_k127_3883483_15 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 412.0
WH2_k127_3883483_16 transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 411.0
WH2_k127_3883483_17 Branched-chain amino acid ATP-binding cassette transporter K01995 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 404.0
WH2_k127_3883483_18 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 416.0
WH2_k127_3883483_19 Creatinine amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 387.0
WH2_k127_3883483_2 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 5.226e-230 724.0
WH2_k127_3883483_20 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 379.0
WH2_k127_3883483_21 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 370.0
WH2_k127_3883483_22 Bacterial regulatory proteins, gntR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 366.0
WH2_k127_3883483_23 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 361.0
WH2_k127_3883483_24 short-chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000004309 276.0
WH2_k127_3883483_25 FCD - - - 0.000000000000000000000000000000000000000000000000000001342 201.0
WH2_k127_3883483_26 Class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000158 198.0
WH2_k127_3883483_27 sulfate ABC transporter K02046,K15496 - - 0.0000000000000000000000000002474 122.0
WH2_k127_3883483_28 Belongs to the universal stress protein A family - - - 0.0000000000000000000000002502 117.0
WH2_k127_3883483_3 helix_turn_helix gluconate operon transcriptional repressor - - - 7.902e-203 640.0
WH2_k127_3883483_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 580.0
WH2_k127_3883483_5 monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 531.0
WH2_k127_3883483_6 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 514.0
WH2_k127_3883483_7 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 528.0
WH2_k127_3883483_8 sulfate ABC transporter K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 500.0
WH2_k127_3883483_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 486.0
WH2_k127_3910880_0 aminopeptidase N K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 2.018e-320 1007.0
WH2_k127_3910880_1 Asparagine synthase K01953 - 6.3.5.4 2.693e-223 707.0
WH2_k127_3910880_10 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 463.0
WH2_k127_3910880_11 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 465.0
WH2_k127_3910880_12 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 452.0
WH2_k127_3910880_13 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 412.0
WH2_k127_3910880_14 depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 428.0
WH2_k127_3910880_15 Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 410.0
WH2_k127_3910880_16 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 393.0
WH2_k127_3910880_17 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 379.0
WH2_k127_3910880_18 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 361.0
WH2_k127_3910880_19 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 352.0
WH2_k127_3910880_2 Involved in beta-(1-- 2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation K06147 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 1.175e-197 632.0
WH2_k127_3910880_20 Histidine kinase K07638 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 359.0
WH2_k127_3910880_21 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 345.0
WH2_k127_3910880_22 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 342.0
WH2_k127_3910880_23 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 343.0
WH2_k127_3910880_24 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 333.0
WH2_k127_3910880_25 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 323.0
WH2_k127_3910880_26 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 319.0
WH2_k127_3910880_27 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 302.0
WH2_k127_3910880_28 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001235 302.0
WH2_k127_3910880_29 - - - - 0.0000000000000000000000000000000000000000000000000000000000004667 229.0
WH2_k127_3910880_3 protein conserved in bacteria K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 605.0
WH2_k127_3910880_30 - - - - 0.00000000000000000000000000000000000000000000000000000000006721 207.0
WH2_k127_3910880_31 Sugar (and other) transporter K07552 - - 0.000000000000000000000000000000000000000000000000008206 192.0
WH2_k127_3910880_32 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000003714 188.0
WH2_k127_3910880_33 transglycosylase - - - 0.00000000000000000000000000000000000000000000002724 181.0
WH2_k127_3910880_34 ligase and related enzymes - - - 0.00000000000000000000000000001392 136.0
WH2_k127_3910880_35 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000002261 114.0
WH2_k127_3910880_36 cheY-homologous receiver domain - - - 0.0000000000000000000000000065 114.0
WH2_k127_3910880_37 COG0550 Topoisomerase IA K03168 - 5.99.1.2 0.0000000000008065 78.0
WH2_k127_3910880_38 Sulfite exporter TauE/SafE K07090 - - 0.0000003245 57.0
WH2_k127_3910880_39 - - - - 0.000001771 59.0
WH2_k127_3910880_4 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 559.0
WH2_k127_3910880_40 Helix-turn-helix XRE-family like proteins K21498 - - 0.00001349 52.0
WH2_k127_3910880_41 Bacterial DNA topoisomeraes I ATP-binding domain K03169 - 5.99.1.2 0.00005173 54.0
WH2_k127_3910880_42 - - - - 0.0002224 46.0
WH2_k127_3910880_5 peptidase M24 K01271,K15783 - 3.4.13.9,3.5.4.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 527.0
WH2_k127_3910880_6 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 531.0
WH2_k127_3910880_7 N-terminal TM domain of oligopeptide transport permease C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 488.0
WH2_k127_3910880_8 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 480.0
WH2_k127_3910880_9 ATPase (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 474.0
WH2_k127_3933560_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296 - - 0.0 1583.0
WH2_k127_3933560_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 472.0
WH2_k127_3933560_10 Gene 25-like lysozyme - - - 0.00000001204 63.0
WH2_k127_3933560_2 Type VI secretion system, TssF K11896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 422.0
WH2_k127_3933560_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 398.0
WH2_k127_3933560_4 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000003169 265.0
WH2_k127_3933560_5 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006879 247.0
WH2_k127_3933560_6 Type VI secretion, TssG K11895 - - 0.0000000000000000000000000000000000000000000000004288 192.0
WH2_k127_3933560_7 TIGRFAM type VI secretion ATPase, ClpV1 family K11907 - - 0.0000000000000000000000000000007321 128.0
WH2_k127_3933560_8 This family consists of several bacterial proteins of K11903 - - 0.000000000000000000173 95.0
WH2_k127_3933560_9 This family consists of several bacterial proteins of K11903 - - 0.0000000000000005807 81.0
WH2_k127_3965786_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1368.0
WH2_k127_3965786_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K03418 - 3.5.1.56 2.964e-314 978.0
WH2_k127_3965786_10 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 387.0
WH2_k127_3965786_11 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 399.0
WH2_k127_3965786_12 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 373.0
WH2_k127_3965786_13 Sugar (and other) transporter K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 350.0
WH2_k127_3965786_14 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000583 276.0
WH2_k127_3965786_15 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000358 226.0
WH2_k127_3965786_16 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000009266 216.0
WH2_k127_3965786_17 Lrp/AsnC ligand binding domain K03719 - - 0.0000000000000000000000000000000000000000000000000000000001066 207.0
WH2_k127_3965786_18 - - - - 0.0000000000000000000000000000000000000000003264 160.0
WH2_k127_3965786_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000007548 152.0
WH2_k127_3965786_2 ABC-type dipeptide transport system periplasmic component K02035 - - 1.669e-208 661.0
WH2_k127_3965786_20 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000003635 163.0
WH2_k127_3965786_21 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000003866 153.0
WH2_k127_3965786_22 ParB-like nuclease domain - - - 0.0000000000000000000000000406 109.0
WH2_k127_3965786_3 COG0744 Membrane carboxypeptidase (penicillin-binding protein) K05366 - 2.4.1.129,3.4.16.4 1.079e-198 641.0
WH2_k127_3965786_4 Bacterial extracellular solute-binding protein K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 589.0
WH2_k127_3965786_5 Cys/Met metabolism PLP-dependent enzyme K01758,K01761 - 4.4.1.1,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 510.0
WH2_k127_3965786_6 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 485.0
WH2_k127_3965786_7 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 446.0
WH2_k127_3965786_8 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 436.0
WH2_k127_3965786_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 408.0
WH2_k127_3991014_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000001733 220.0
WH2_k127_3991014_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000004359 217.0
WH2_k127_3991014_2 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000008836 132.0
WH2_k127_3991014_3 regulator of chromosome condensation, RCC1 - - - 0.0000000242 65.0
WH2_k127_3991809_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.898e-221 700.0
WH2_k127_3991809_1 Na+/Pi-cotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 556.0
WH2_k127_3991809_10 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000001556 160.0
WH2_k127_3991809_11 CAAX protease self-immunity K07052 - - 0.0000000001515 72.0
WH2_k127_3991809_2 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 443.0
WH2_k127_3991809_3 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 377.0
WH2_k127_3991809_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 346.0
WH2_k127_3991809_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 312.0
WH2_k127_3991809_6 Histidine kinase-like ATPases K14980 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 320.0
WH2_k127_3991809_7 Transcriptional regulatory protein, C terminal K14981 - - 0.000000000000000000000000000000000000000000000000000000000006368 217.0
WH2_k127_3991809_8 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000002704 215.0
WH2_k127_3991809_9 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000003462 183.0
WH2_k127_4010900_0 FAD dependent oxidoreductase K07137 - - 1.788e-275 854.0
WH2_k127_4010900_1 Sulfatase K01133 - 3.1.6.6 1.793e-211 671.0
WH2_k127_4010900_10 PFAM regulatory protein LysR K03566 - - 0.000000000000000000000000000000000000000000000000000000000001168 221.0
WH2_k127_4010900_11 LysR family - - - 0.00000000000000000000000000000000000000000000000000000000001211 217.0
WH2_k127_4010900_12 Lactoylglutathione lyase - - - 0.000000000000000000000000000000000000000000000000001356 186.0
WH2_k127_4010900_13 COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) K14189 - - 0.00000000000000000000000000000000000000000000000001124 188.0
WH2_k127_4010900_2 Oxidative deamination of D-amino acids K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 617.0
WH2_k127_4010900_3 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 501.0
WH2_k127_4010900_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 458.0
WH2_k127_4010900_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 425.0
WH2_k127_4010900_6 ABC-type proline glycine betaine transport systems periplasmic components K02002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 397.0
WH2_k127_4010900_7 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 321.0
WH2_k127_4010900_8 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006114 284.0
WH2_k127_4010900_9 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000000000000000000000000000000000000001727 227.0
WH2_k127_4014433_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1196.0
WH2_k127_4014433_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 9.655e-206 646.0
WH2_k127_4014433_2 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 498.0
WH2_k127_4014433_3 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 405.0
WH2_k127_4014433_4 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 354.0
WH2_k127_4014433_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005328 272.0
WH2_k127_4014433_6 metal ion transport K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001499 266.0
WH2_k127_4014433_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000483 103.0
WH2_k127_4014433_8 Histidine kinase - - - 0.0000000000000000000008007 102.0
WH2_k127_4031947_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 399.0
WH2_k127_4031947_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 377.0
WH2_k127_4031947_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002902 281.0
WH2_k127_4031947_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000002506 205.0
WH2_k127_4064087_0 COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases K02230 - 6.6.1.2 8.426e-311 971.0
WH2_k127_4064087_1 CobB/CobQ-like glutamine amidotransferase domain K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 480.0
WH2_k127_4064087_10 - - - - 0.00000000000000000000000009897 108.0
WH2_k127_4064087_11 Tripartite tricarboxylate transporter family receptor - - - 0.000002038 59.0
WH2_k127_4064087_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 425.0
WH2_k127_4064087_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 404.0
WH2_k127_4064087_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 388.0
WH2_k127_4064087_5 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 304.0
WH2_k127_4064087_6 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 313.0
WH2_k127_4064087_7 PFAM Aminotransferase class I and II K02225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 304.0
WH2_k127_4064087_8 helix_turn_helix ASNC type K05800 - - 0.000000000000000000000000000000000000000000000000000000000000000000005136 237.0
WH2_k127_4064087_9 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000002886 173.0
WH2_k127_4089110_0 Fumarate reductase flavoprotein C-term K00394 - 1.8.99.2 3.053e-316 974.0
WH2_k127_4089110_1 Amidohydrolase family - - - 3.136e-235 734.0
WH2_k127_4089110_10 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 313.0
WH2_k127_4089110_11 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 299.0
WH2_k127_4089110_12 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003022 256.0
WH2_k127_4089110_13 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001708 247.0
WH2_k127_4089110_14 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000001218 243.0
WH2_k127_4089110_15 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000007669 223.0
WH2_k127_4089110_16 Cytochrome B561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000004071 221.0
WH2_k127_4089110_17 - - - - 0.00000000000000000000000000000000000000000000000006691 188.0
WH2_k127_4089110_18 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000891 159.0
WH2_k127_4089110_19 Small multidrug resistance protein K11741 - - 0.00000000000000000000000004851 113.0
WH2_k127_4089110_2 Transmembrane secretion effector - - - 2.532e-209 668.0
WH2_k127_4089110_20 ATPases associated with a variety of cellular activities K02049,K15555 - - 0.00000000000000005249 82.0
WH2_k127_4089110_21 This family consists of several bacterial proteins of K11903 - - 0.000000000000001501 79.0
WH2_k127_4089110_23 Transposase DDE domain - - - 0.0000000008558 61.0
WH2_k127_4089110_24 ATPases associated with a variety of cellular activities K02049,K15555 - - 0.00000003111 57.0
WH2_k127_4089110_3 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 597.0
WH2_k127_4089110_4 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 590.0
WH2_k127_4089110_5 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 488.0
WH2_k127_4089110_6 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 449.0
WH2_k127_4089110_7 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 384.0
WH2_k127_4089110_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 383.0
WH2_k127_4089110_9 Has an organic peroxide-dependent peroxidase activity K03781 - 1.11.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 366.0
WH2_k127_4091357_0 Phytochrome central region domain protein - - - 3.727e-273 860.0
WH2_k127_4091357_1 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K02029 - 3.6.3.21 2.621e-262 818.0
WH2_k127_4091357_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 449.0
WH2_k127_4091357_11 Amino acid ABC transporter substrate-binding protein, PAAT family K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 448.0
WH2_k127_4091357_12 Binding-protein-dependent transport system inner membrane component K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 416.0
WH2_k127_4091357_13 Binding-protein-dependent transport system inner membrane component K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 421.0
WH2_k127_4091357_14 Binding-protein-dependent transport system inner membrane component K15554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 394.0
WH2_k127_4091357_15 transcriptional regulator, lysr family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 387.0
WH2_k127_4091357_16 NLPA lipoprotein K02073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 374.0
WH2_k127_4091357_17 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 375.0
WH2_k127_4091357_18 Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 344.0
WH2_k127_4091357_19 NADP oxidoreductase coenzyme F420-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 336.0
WH2_k127_4091357_2 Luciferase-like monooxygenase K04091 - 1.14.14.5 3.306e-207 649.0
WH2_k127_4091357_20 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000222 279.0
WH2_k127_4091357_21 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 258.0
WH2_k127_4091357_22 ABC transporter K02028,K02045,K02049 - 3.6.3.21,3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000001681 247.0
WH2_k127_4091357_23 thiamine-containing compound biosynthetic process K02051,K15553 - - 0.0000000000000000000000000000000000000000000000000000000000000009058 230.0
WH2_k127_4091357_24 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000004983 224.0
WH2_k127_4091357_25 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000009841 231.0
WH2_k127_4091357_26 Heme oxygenase K07215 - 1.14.99.58 0.0000000000000000000000000000001227 131.0
WH2_k127_4091357_27 thiamine-containing compound biosynthetic process K02051 - - 0.0000004508 61.0
WH2_k127_4091357_3 monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 602.0
WH2_k127_4091357_4 Bacterial periplasmic substrate-binding proteins K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 554.0
WH2_k127_4091357_5 PFAM Peptidase family M20 M25 M40, Peptidase dimerization domain K01451 - 3.5.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 543.0
WH2_k127_4091357_6 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 525.0
WH2_k127_4091357_7 TIGRFAM aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein K02051,K15553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 482.0
WH2_k127_4091357_8 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 504.0
WH2_k127_4091357_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 487.0
WH2_k127_4124818_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1090.0
WH2_k127_4124818_1 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 391.0
WH2_k127_4124818_10 Cupin domain - - - 0.0000000000000000000000000008108 121.0
WH2_k127_4124818_11 Protein conserved in bacteria K09991 - - 0.0000000000000000001511 97.0
WH2_k127_4124818_12 Phage Tail Collar Domain - - - 0.00000000005745 66.0
WH2_k127_4124818_2 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 385.0
WH2_k127_4124818_3 DNA-dependent RNA polymerase K21313 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 388.0
WH2_k127_4124818_4 Catechol dioxygenase N terminus K03381 - 1.13.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 362.0
WH2_k127_4124818_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001037 284.0
WH2_k127_4124818_6 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008295 254.0
WH2_k127_4124818_7 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000001441 184.0
WH2_k127_4124818_8 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000000000000005219 157.0
WH2_k127_4124818_9 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000565 137.0
WH2_k127_4140157_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.859e-251 782.0
WH2_k127_4140157_1 Amidohydrolase family K01464 - 3.5.2.2 7.034e-245 764.0
WH2_k127_4140157_10 Glyoxalase bleomycin resistance protein dioxygenase K00462,K14583,K16049 - 1.13.11.25,1.13.11.39,1.13.11.56 0.00000000000000000000000000000000000000000000000000000000000000000000003743 251.0
WH2_k127_4140157_11 YcdC-like protein, C-terminal region K09017 - - 0.000000000000000000000000000000000000000000000000000000000003264 216.0
WH2_k127_4140157_12 Regulatory protein tetr - - - 0.00000000000000000000000000000000000000002284 161.0
WH2_k127_4140157_13 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.000000000000000000000000000323 117.0
WH2_k127_4140157_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 6.171e-229 718.0
WH2_k127_4140157_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 566.0
WH2_k127_4140157_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 462.0
WH2_k127_4140157_5 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 419.0
WH2_k127_4140157_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 370.0
WH2_k127_4140157_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 348.0
WH2_k127_4140157_8 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006905 274.0
WH2_k127_4140157_9 PFAM histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002926 247.0
WH2_k127_4153322_0 Orn/Lys/Arg decarboxylase, N-terminal domain K01581 - 4.1.1.17 0.0 1262.0
WH2_k127_4153322_1 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 4.145e-228 717.0
WH2_k127_4153322_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000004471 214.0
WH2_k127_4153322_3 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000002834 143.0
WH2_k127_4171929_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 467.0
WH2_k127_4171929_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009033 410.0
WH2_k127_4171929_2 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000142 256.0
WH2_k127_4171929_3 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000003604 246.0
WH2_k127_4171929_4 Major Facilitator Superfamily - - - 0.0000000000000000037 91.0
WH2_k127_4185818_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.364e-218 687.0
WH2_k127_4185818_1 transport systems, ATPase components K02056 - 3.6.3.17 3.08e-205 652.0
WH2_k127_4185818_10 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 352.0
WH2_k127_4185818_11 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 346.0
WH2_k127_4185818_12 PFAM Alcohol dehydrogenase zinc-binding domain protein K00001,K07119 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 342.0
WH2_k127_4185818_13 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 309.0
WH2_k127_4185818_14 Amino acid synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001244 292.0
WH2_k127_4185818_15 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003371 284.0
WH2_k127_4185818_16 Amino acid synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001315 274.0
WH2_k127_4185818_17 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001489 269.0
WH2_k127_4185818_18 COG3327 Phenylacetic acid-responsive transcriptional repressor K02616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001783 249.0
WH2_k127_4185818_19 iron-storage protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000003014 238.0
WH2_k127_4185818_2 Amidohydrolase family K15358 - 3.5.2.18 8.212e-203 637.0
WH2_k127_4185818_20 Phenylacetic acid degradation protein PaaD K02614 - - 0.000000000000000000000000000000000000000000000000000002135 207.0
WH2_k127_4185818_21 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000001072 187.0
WH2_k127_4185818_22 transcriptional regulator, TetR family K09017 - - 0.000000000000000000000000000000000000000000000008442 178.0
WH2_k127_4185818_23 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000248 166.0
WH2_k127_4185818_24 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000003563 140.0
WH2_k127_4185818_25 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.000000000000000001491 88.0
WH2_k127_4185818_26 BFD-like [2Fe-2S] binding domain K02192 - - 0.000000000001284 71.0
WH2_k127_4185818_27 - - - - 0.0000000004356 64.0
WH2_k127_4185818_3 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 555.0
WH2_k127_4185818_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 477.0
WH2_k127_4185818_5 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 440.0
WH2_k127_4185818_6 hydrolase NrgC K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 438.0
WH2_k127_4185818_7 Histidine phosphatase superfamily (branch 2) K01085,K01093 - 3.1.3.10,3.1.3.2,3.1.3.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 428.0
WH2_k127_4185818_8 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 416.0
WH2_k127_4185818_9 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 407.0
WH2_k127_4212962_0 Bacterial extracellular solute-binding protein - - - 1.723e-285 884.0
WH2_k127_4212962_1 CoA-transferase family III - - - 1.37e-209 656.0
WH2_k127_4212962_10 permease K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 457.0
WH2_k127_4212962_11 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 461.0
WH2_k127_4212962_12 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 434.0
WH2_k127_4212962_13 Bacterial regulatory proteins, lacI family K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 433.0
WH2_k127_4212962_14 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 413.0
WH2_k127_4212962_15 Glycosyl transferase family 41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 415.0
WH2_k127_4212962_16 enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 371.0
WH2_k127_4212962_17 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 353.0
WH2_k127_4212962_18 TIGRFAM TIGR03032 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 365.0
WH2_k127_4212962_19 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008076 235.0
WH2_k127_4212962_2 Domain of unknown function (DUF4432) - - - 1.132e-203 640.0
WH2_k127_4212962_20 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000006895 245.0
WH2_k127_4212962_21 COG3637 Opacity protein and related surface antigens - - - 0.000000000000000000000000000000001238 138.0
WH2_k127_4212962_23 metal-binding protein - - - 0.00000000000000000000000000000001721 129.0
WH2_k127_4212962_24 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000008324 79.0
WH2_k127_4212962_25 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000001078 59.0
WH2_k127_4212962_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 586.0
WH2_k127_4212962_4 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 544.0
WH2_k127_4212962_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 531.0
WH2_k127_4212962_6 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 505.0
WH2_k127_4212962_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 507.0
WH2_k127_4212962_8 Belongs to the ABC transporter superfamily K10111,K10112,K10191 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 485.0
WH2_k127_4212962_9 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 477.0
WH2_k127_4216284_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 538.0
WH2_k127_4216284_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 511.0
WH2_k127_4216284_2 protein conserved in bacteria K09798 - - 0.000000000000000000000000000000000000000000000000000000000003543 225.0
WH2_k127_4216284_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000003667 220.0
WH2_k127_4216284_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000001436 172.0
WH2_k127_4216284_5 COG4942 Membrane-bound metallopeptidase - - - 0.000000000000000000000000000000000000001402 153.0
WH2_k127_4216284_6 Gluconate - - - 0.000000000000009874 79.0
WH2_k127_4227719_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.619e-216 684.0
WH2_k127_4227719_1 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001547 253.0
WH2_k127_4227719_2 COG1124 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02032 - - 0.000000000000000000000000000000000000000000004121 166.0
WH2_k127_4230479_0 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000004305 192.0
WH2_k127_4230479_1 Type IV secretory system Conjugative DNA transfer K03205 - - 0.000000000000000000000000000000000005969 156.0
WH2_k127_4230479_10 Belongs to the peptidase S8 family - - - 0.0009029 50.0
WH2_k127_4230479_2 Type II secretory pathway, component PulD - - - 0.0000000000000000000000000000000003774 150.0
WH2_k127_4230479_3 type II secretion system protein - - - 0.00000000000000000000001072 114.0
WH2_k127_4230479_4 Bacterial shufflon protein, N-terminal constant region - - - 0.000000000000000000000844 107.0
WH2_k127_4230479_5 COG3504 Type IV secretory pathway, VirB9 components - - - 0.00000000000002295 85.0
WH2_k127_4230479_6 PilM - - - 0.0000007264 58.0
WH2_k127_4230479_7 COG3451 Type IV secretory pathway, VirB4 components K03199,K20530 - - 0.00009603 56.0
WH2_k127_4230479_8 PFAM Toxin co-regulated pilus biosynthesis protein Q - - - 0.0001952 50.0
WH2_k127_4230479_9 Pilin accessory protein (PilO) - - - 0.0004374 52.0
WH2_k127_4238049_0 C-terminal, D2-small domain, of ClpB protein K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1116.0
WH2_k127_4238049_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 6.777e-236 737.0
WH2_k127_4238049_10 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003056 252.0
WH2_k127_4238049_11 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000007933 220.0
WH2_k127_4238049_12 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000007736 204.0
WH2_k127_4238049_13 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000037 177.0
WH2_k127_4238049_14 - - - - 0.000000000000000000000000000000000000000000005286 172.0
WH2_k127_4238049_15 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000001981 154.0
WH2_k127_4238049_16 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000005568 149.0
WH2_k127_4238049_17 - - - - 0.000000000000000000000000000000000006878 142.0
WH2_k127_4238049_18 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000001251 136.0
WH2_k127_4238049_19 membrane K08987 - - 0.00000000000000000000000000002305 134.0
WH2_k127_4238049_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 4.207e-202 640.0
WH2_k127_4238049_20 Phasin protein - - - 0.000000000000000000000000003196 118.0
WH2_k127_4238049_21 PFAM YhhN-like protein - - - 0.0000001289 62.0
WH2_k127_4238049_22 Tripartite tricarboxylate transporter family receptor - - - 0.000748 53.0
WH2_k127_4238049_3 phosphomannomutase K01840 - 5.4.2.8 5.89e-197 623.0
WH2_k127_4238049_4 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 530.0
WH2_k127_4238049_5 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 418.0
WH2_k127_4238049_6 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 364.0
WH2_k127_4238049_7 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 312.0
WH2_k127_4238049_8 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 309.0
WH2_k127_4238049_9 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 296.0
WH2_k127_4243527_0 - K03418 - 3.5.1.56 1.356e-282 886.0
WH2_k127_4243527_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 561.0
WH2_k127_4243527_10 Binding-protein-dependent transport system inner membrane component K11078 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 310.0
WH2_k127_4243527_11 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006995 254.0
WH2_k127_4243527_12 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000003244 216.0
WH2_k127_4243527_13 - - - - 0.0000000000000000000000000000000001145 136.0
WH2_k127_4243527_14 PFAM type III effector Hrp-dependent outers K21948 - 2.7.1.217 0.00003034 49.0
WH2_k127_4243527_2 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 560.0
WH2_k127_4243527_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 472.0
WH2_k127_4243527_4 Bacterial extracellular solute-binding protein K11077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 426.0
WH2_k127_4243527_5 Transketolase, thiamine diphosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 419.0
WH2_k127_4243527_6 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 392.0
WH2_k127_4243527_7 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02049,K02052,K11080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 387.0
WH2_k127_4243527_8 ABC transporter (Permease) K11079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 341.0
WH2_k127_4243527_9 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 318.0
WH2_k127_4262124_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 614.0
WH2_k127_4262124_1 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 382.0
WH2_k127_4262124_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000004785 121.0
WH2_k127_4266676_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.186e-261 814.0
WH2_k127_4266676_1 argininosuccinate lyase K01755 - 4.3.2.1 2.691e-207 664.0
WH2_k127_4266676_10 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 522.0
WH2_k127_4266676_11 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 501.0
WH2_k127_4266676_12 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 488.0
WH2_k127_4266676_13 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 446.0
WH2_k127_4266676_14 ABC transporter transmembrane region K16013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 420.0
WH2_k127_4266676_15 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 361.0
WH2_k127_4266676_16 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 365.0
WH2_k127_4266676_17 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 351.0
WH2_k127_4266676_18 COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components K16012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 366.0
WH2_k127_4266676_19 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 338.0
WH2_k127_4266676_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 3.589e-206 646.0
WH2_k127_4266676_20 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 326.0
WH2_k127_4266676_21 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 316.0
WH2_k127_4266676_22 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 292.0
WH2_k127_4266676_23 COG1560 Lauroyl myristoyl acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 304.0
WH2_k127_4266676_24 protein conserved in bacteria K09778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000252 257.0
WH2_k127_4266676_25 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000003082 236.0
WH2_k127_4266676_26 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001762 233.0
WH2_k127_4266676_27 - - - - 0.000000000000000000000000000000000000000000000000000000002033 209.0
WH2_k127_4266676_28 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.00000000000000000000000000000000000000000000000000000004473 207.0
WH2_k127_4266676_29 Thioredoxin-like - - - 0.00000000000000000000000000000000000000006297 173.0
WH2_k127_4266676_3 ABC-type multidrug transport system, ATPase and permease K06147,K11085 - - 8.226e-202 644.0
WH2_k127_4266676_30 FR47-like protein - - - 0.0000000000000000000000000000000003237 138.0
WH2_k127_4266676_31 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000001525 128.0
WH2_k127_4266676_32 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000007347 138.0
WH2_k127_4266676_33 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000003786 115.0
WH2_k127_4266676_34 Cyd operon protein YbgT K00424 - 1.10.3.14 0.000000000005794 68.0
WH2_k127_4266676_35 Domain of unknown function (DUF1127) - - - 0.0000000015 68.0
WH2_k127_4266676_36 - - - - 0.0002 53.0
WH2_k127_4266676_37 Domain of unknown function (DUF4880) K07165 - - 0.0002762 46.0
WH2_k127_4266676_4 ABC-type branched-chain amino acid transport systems periplasmic component K01999 - - 6.917e-199 625.0
WH2_k127_4266676_5 Domain of unknown function (DUF4175) - - - 7.883e-195 636.0
WH2_k127_4266676_6 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 604.0
WH2_k127_4266676_7 oxidase, subunit K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 582.0
WH2_k127_4266676_8 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 561.0
WH2_k127_4266676_9 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 559.0
WH2_k127_4327229_0 acyl-CoA dehydrogenase K09456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 589.0
WH2_k127_4327229_1 Belongs to the proline racemase family K12658 GO:0003674,GO:0003824,GO:0006575,GO:0006577,GO:0006579,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0036361,GO:0042219,GO:0044237,GO:0044248,GO:0044270,GO:0047580,GO:0047661,GO:0071704,GO:1901564,GO:1901565,GO:1901575 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 556.0
WH2_k127_4327229_10 belongs to the bacterial solute-binding protein 3 family K02030,K09996,K10014,K10022 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001021 287.0
WH2_k127_4327229_11 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001654 302.0
WH2_k127_4327229_12 Binding-protein-dependent transport system inner membrane component K02029,K10020 - - 0.000000000000000000000000000000000000000000000000000000000000000000007116 240.0
WH2_k127_4327229_13 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001396 236.0
WH2_k127_4327229_14 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000004862 202.0
WH2_k127_4327229_15 Belongs to the RNase T2 family K01166,K01169 - 3.1.27.1,3.1.27.6 0.000000000000000000000000000000000000000000000001288 188.0
WH2_k127_4327229_16 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000001877 186.0
WH2_k127_4327229_17 Protein of unknown function (DUF454) K09790 - - 0.000000000000000000000000000000000000000000004102 166.0
WH2_k127_4327229_18 Transcriptional - - - 0.0000000000000000000000000000000000000000001248 168.0
WH2_k127_4327229_19 -acetyltransferase - - - 0.0000000000000000000000000000000000000000001424 166.0
WH2_k127_4327229_2 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 456.0
WH2_k127_4327229_20 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000001567 79.0
WH2_k127_4327229_21 Hemimethylated DNA-binding protein YccV like K11940 - - 0.00000000003291 63.0
WH2_k127_4327229_22 Protein conserved in bacteria - - - 0.00001048 57.0
WH2_k127_4327229_3 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 443.0
WH2_k127_4327229_4 Belongs to the proline racemase family K01777 - 5.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 430.0
WH2_k127_4327229_5 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 424.0
WH2_k127_4327229_6 Belongs to the DapA family K21062 - 3.5.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 409.0
WH2_k127_4327229_7 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 396.0
WH2_k127_4327229_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 385.0
WH2_k127_4327229_9 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 286.0
WH2_k127_4329022_0 Dehydratase family K13875 - 4.2.1.25 3.452e-237 737.0
WH2_k127_4329022_1 Dihydrodipicolinate synthetase family K13876 - 4.2.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 574.0
WH2_k127_4329022_2 Histidine kinase - - - 0.0000000000000000000000000000000000007451 158.0
WH2_k127_4331470_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 616.0
WH2_k127_4331470_1 ATP-binding protein K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 532.0
WH2_k127_4331470_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008117 264.0
WH2_k127_4331470_3 - - - - 0.00000695 52.0
WH2_k127_4344856_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 9.874e-196 623.0
WH2_k127_4344856_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 602.0
WH2_k127_4344856_10 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 420.0
WH2_k127_4344856_11 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 400.0
WH2_k127_4344856_12 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001468 254.0
WH2_k127_4344856_13 LysR substrate binding domain K03566,K17850 - - 0.0000000000005176 70.0
WH2_k127_4344856_2 ABC-type Fe3 transport system, periplasmic component K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 590.0
WH2_k127_4344856_3 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 562.0
WH2_k127_4344856_4 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 532.0
WH2_k127_4344856_5 Belongs to the ABC transporter superfamily K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 522.0
WH2_k127_4344856_6 dioxygenase K00471 - 1.14.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 512.0
WH2_k127_4344856_7 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 477.0
WH2_k127_4344856_8 Binding-protein-dependent transport system inner membrane component K02054,K11079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 477.0
WH2_k127_4344856_9 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 455.0
WH2_k127_4356023_0 Bacterial extracellular solute-binding proteins, family 5 Middle K12368 - - 4.649e-260 814.0
WH2_k127_4356023_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 4.949e-217 683.0
WH2_k127_4356023_10 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 314.0
WH2_k127_4356023_11 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000000000000000007147 203.0
WH2_k127_4356023_12 HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000489 199.0
WH2_k127_4356023_13 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.000000000000000000000000000000000000000000000000005503 184.0
WH2_k127_4356023_14 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000000000000001972 156.0
WH2_k127_4356023_15 Conserved TM helix K03442 - - 0.000000000000000000000000000000000000000117 166.0
WH2_k127_4356023_16 - - - - 0.0000001514 57.0
WH2_k127_4356023_17 Protein of unknown function (DUF423) - - - 0.0000001565 58.0
WH2_k127_4356023_18 Bacterial protein of unknown function (DUF853) K06915 - - 0.000001775 51.0
WH2_k127_4356023_19 Tetratricopeptide repeat - - - 0.000003715 59.0
WH2_k127_4356023_2 Binding-protein-dependent transport system inner membrane component K12369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 497.0
WH2_k127_4356023_3 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 502.0
WH2_k127_4356023_4 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 486.0
WH2_k127_4356023_5 Belongs to the ABC transporter superfamily K02031,K12371 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 444.0
WH2_k127_4356023_6 N-terminal TM domain of oligopeptide transport permease C K12370 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 413.0
WH2_k127_4356023_7 Oligopeptide/dipeptide transporter, C-terminal region K02032,K12372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 409.0
WH2_k127_4356023_8 hydrolase activity, acting on ester bonds K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 387.0
WH2_k127_4356023_9 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 365.0
WH2_k127_4371519_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 470.0
WH2_k127_4371519_1 Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 420.0
WH2_k127_4371519_2 CrtC N-terminal lipocalin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 339.0
WH2_k127_4371519_3 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002744 276.0
WH2_k127_4371519_4 helix_turn_helix isocitrate lyase regulation K02624,K20539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002411 246.0
WH2_k127_4371519_5 FCD K11475 - - 0.0000000000000000000000000000000000000000000000000000465 196.0
WH2_k127_4371519_6 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000002524 128.0
WH2_k127_4371519_7 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000001324 94.0
WH2_k127_4371519_8 Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - 0.000000000000000006946 84.0
WH2_k127_4386737_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.948e-308 957.0
WH2_k127_4386737_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 4.087e-273 864.0
WH2_k127_4386737_10 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 462.0
WH2_k127_4386737_11 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 443.0
WH2_k127_4386737_12 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 451.0
WH2_k127_4386737_13 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 426.0
WH2_k127_4386737_14 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 362.0
WH2_k127_4386737_15 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 340.0
WH2_k127_4386737_16 Carboxylesterase K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 335.0
WH2_k127_4386737_17 Rieske [2Fe-2S] domain K22325 - 1.14.15.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 316.0
WH2_k127_4386737_18 Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 301.0
WH2_k127_4386737_19 Protein of unknown function (DUF1442) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006644 260.0
WH2_k127_4386737_2 PFAM extracellular solute-binding protein family 5 K02035 - - 1.712e-271 843.0
WH2_k127_4386737_20 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003574 258.0
WH2_k127_4386737_21 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002601 242.0
WH2_k127_4386737_22 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000005913 235.0
WH2_k127_4386737_23 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000025 240.0
WH2_k127_4386737_24 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000007473 243.0
WH2_k127_4386737_25 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000385 225.0
WH2_k127_4386737_26 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000002154 222.0
WH2_k127_4386737_27 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000001544 187.0
WH2_k127_4386737_28 Alpha beta hydrolase K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000004091 181.0
WH2_k127_4386737_29 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000000000000000000000000000000000000000001869 177.0
WH2_k127_4386737_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.961e-248 771.0
WH2_k127_4386737_30 Protein of unknown function (DUF2000) - - - 0.0000000000000000000000000000000000000002064 153.0
WH2_k127_4386737_31 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000001235 163.0
WH2_k127_4386737_32 PFAM response regulator receiver - - - 0.0000000000000000000003343 102.0
WH2_k127_4386737_4 MlrC C-terminus - - - 2.555e-214 694.0
WH2_k127_4386737_5 Beta-Casp domain K07576 - - 9.745e-212 671.0
WH2_k127_4386737_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 512.0
WH2_k127_4386737_7 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 472.0
WH2_k127_4386737_8 Helix-turn-helix domain, rpiR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 461.0
WH2_k127_4386737_9 PAS fold K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 456.0
WH2_k127_4389917_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1252.0
WH2_k127_4389917_1 Bacterial extracellular solute-binding protein K02055 - - 7.632e-260 804.0
WH2_k127_4389917_10 TOBE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 456.0
WH2_k127_4389917_11 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 438.0
WH2_k127_4389917_12 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 436.0
WH2_k127_4389917_13 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 448.0
WH2_k127_4389917_14 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 413.0
WH2_k127_4389917_15 Putative exopolysaccharide Exporter (EPS-E) K21012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 413.0
WH2_k127_4389917_16 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 413.0
WH2_k127_4389917_17 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 387.0
WH2_k127_4389917_18 lipid-transfer protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 373.0
WH2_k127_4389917_19 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 369.0
WH2_k127_4389917_2 Participates in both transcription termination and antitermination K02600 - - 4.612e-233 731.0
WH2_k127_4389917_20 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 366.0
WH2_k127_4389917_21 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 352.0
WH2_k127_4389917_22 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 314.0
WH2_k127_4389917_23 Gaf domain K02584,K07713,K11908,K12266,K15836,K21009,K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 312.0
WH2_k127_4389917_24 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008901 274.0
WH2_k127_4389917_25 Glycoside-hydrolase family GH114 K21006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004146 253.0
WH2_k127_4389917_26 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007197 245.0
WH2_k127_4389917_27 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001027 240.0
WH2_k127_4389917_28 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20971 - - 0.00000000000000000000000000000000000000000000000000000000000000003433 247.0
WH2_k127_4389917_29 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000001219 222.0
WH2_k127_4389917_3 AMP-binding enzyme C-terminal domain - - - 6.353e-205 654.0
WH2_k127_4389917_30 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.00000000000000000000000000000000000000000000000000000001144 206.0
WH2_k127_4389917_31 Enoyl-CoA hydratase/isomerase K18570 - - 0.0000000000000000000000000000000000000000000000000003609 194.0
WH2_k127_4389917_32 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000001596 204.0
WH2_k127_4389917_33 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000004887 184.0
WH2_k127_4389917_34 peptidyl-tyrosine sulfation K21010 - - 0.00000000000000000000000000000000000000001152 172.0
WH2_k127_4389917_35 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000000000000000003889 139.0
WH2_k127_4389917_36 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000007533 132.0
WH2_k127_4389917_37 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000007722 111.0
WH2_k127_4389917_38 domain, Protein K01674,K03646 - 4.2.1.1 0.000000000000000000119 106.0
WH2_k127_4389917_39 COG0457 FOG TPR repeat - - - 0.00000000003229 78.0
WH2_k127_4389917_4 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 601.0
WH2_k127_4389917_40 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000004252 62.0
WH2_k127_4389917_5 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 587.0
WH2_k127_4389917_6 ATPases associated with a variety of cellular activities K02052,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 550.0
WH2_k127_4389917_7 PFAM TM1410 hypothetical-related protein K21006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 546.0
WH2_k127_4389917_8 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 465.0
WH2_k127_4389917_9 Domain of unknown function (DUF3492) K21011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 477.0
WH2_k127_4402670_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1296.0
WH2_k127_4402670_1 Tripartite tricarboxylate transporter TctA family K07793 - - 1.075e-252 788.0
WH2_k127_4402670_10 LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 368.0
WH2_k127_4402670_11 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 320.0
WH2_k127_4402670_12 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 306.0
WH2_k127_4402670_13 Peptidase family S49 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 295.0
WH2_k127_4402670_14 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003193 285.0
WH2_k127_4402670_15 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001222 264.0
WH2_k127_4402670_16 PFAM OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000004491 202.0
WH2_k127_4402670_17 Methyltransferase small domain K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000001335 180.0
WH2_k127_4402670_18 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000717 172.0
WH2_k127_4402670_19 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000002758 146.0
WH2_k127_4402670_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.696e-244 784.0
WH2_k127_4402670_20 branched-chain amino acid K01999 - - 0.00000000000000000000000000000000001276 143.0
WH2_k127_4402670_21 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000001188 126.0
WH2_k127_4402670_22 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000114 110.0
WH2_k127_4402670_23 cellulose binding K01179 - 3.2.1.4 0.000000002129 72.0
WH2_k127_4402670_24 alginic acid biosynthetic process - - - 0.000000002129 72.0
WH2_k127_4402670_26 - - - - 0.0008767 48.0
WH2_k127_4402670_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 538.0
WH2_k127_4402670_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 499.0
WH2_k127_4402670_5 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 489.0
WH2_k127_4402670_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 458.0
WH2_k127_4402670_7 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 432.0
WH2_k127_4402670_8 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 419.0
WH2_k127_4402670_9 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 396.0
WH2_k127_4419213_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1107.0
WH2_k127_4419213_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.175e-220 693.0
WH2_k127_4419213_10 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 362.0
WH2_k127_4419213_11 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 294.0
WH2_k127_4419213_12 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001214 262.0
WH2_k127_4419213_13 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006047 257.0
WH2_k127_4419213_14 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005261 251.0
WH2_k127_4419213_15 sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000009394 210.0
WH2_k127_4419213_16 FCD - - - 0.0000000000000000000000000000000000000000000000000000004919 201.0
WH2_k127_4419213_17 Cytochrome c K08738 - - 0.00000000000000000000000007464 112.0
WH2_k127_4419213_19 Transposase K07499 - - 0.00000001079 58.0
WH2_k127_4419213_2 negative regulation of transcription, DNA-templated - - - 2.315e-206 659.0
WH2_k127_4419213_20 Integrase core domain K07497 - - 0.0001668 44.0
WH2_k127_4419213_3 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 561.0
WH2_k127_4419213_4 Arabinose efflux permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 510.0
WH2_k127_4419213_5 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 472.0
WH2_k127_4419213_6 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 399.0
WH2_k127_4419213_7 nitrogen compound transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 390.0
WH2_k127_4419213_8 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 394.0
WH2_k127_4419213_9 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 378.0
WH2_k127_445575_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.848e-233 742.0
WH2_k127_445575_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 378.0
WH2_k127_445575_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 331.0
WH2_k127_445575_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 297.0
WH2_k127_445575_4 methyl-accepting chemotaxis K03406 - - 0.00000000000000000000000003686 119.0
WH2_k127_4460106_0 Putative serine dehydratase domain K01753 - 4.3.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 507.0
WH2_k127_4460106_1 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 428.0
WH2_k127_4460106_2 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 384.0
WH2_k127_4460106_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 357.0
WH2_k127_4460106_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 336.0
WH2_k127_4460106_5 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 319.0
WH2_k127_4460106_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001495 258.0
WH2_k127_4460106_7 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000000000008993 194.0
WH2_k127_4460106_8 FCD - - - 0.000000000000000000000000000000000000000005907 164.0
WH2_k127_4460106_9 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000007769 114.0
WH2_k127_4461683_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.221e-223 719.0
WH2_k127_4461683_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 520.0
WH2_k127_4461683_2 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 457.0
WH2_k127_4461683_3 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 385.0
WH2_k127_4461683_4 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007151 281.0
WH2_k127_4461683_5 YbaK prolyl-tRNA synthetase associated - - - 0.000000000000000000000000000000000000000000000000000000001799 205.0
WH2_k127_4461683_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000001368 206.0
WH2_k127_4461683_7 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000002216 187.0
WH2_k127_4472094_0 Carbamoyl-phosphate synthase L chain, ATP-binding - - - 0.0 1153.0
WH2_k127_4472094_1 Aldehyde dehydrogenase family K00130 - 1.2.1.8 1.944e-217 684.0
WH2_k127_4472094_10 transcriptional regulator K09017 - - 0.0000000000000000000006243 104.0
WH2_k127_4472094_2 AMP-binding enzyme K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 592.0
WH2_k127_4472094_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 403.0
WH2_k127_4472094_4 aminopeptidase K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 307.0
WH2_k127_4472094_5 class II Aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009143 277.0
WH2_k127_4472094_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008764 268.0
WH2_k127_4472094_7 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001618 256.0
WH2_k127_4472094_8 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000003638 225.0
WH2_k127_4472094_9 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000008997 138.0
WH2_k127_4472823_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000008775 196.0
WH2_k127_4472823_1 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000005605 167.0
WH2_k127_4472823_2 AsmA family K07290 - - 0.000000000000000000000532 101.0
WH2_k127_4472823_3 Protein of unknown function (DUF3309) - - - 0.00000000000000001964 82.0
WH2_k127_4472823_4 - - - - 0.00000003718 59.0
WH2_k127_4506164_0 malic enzyme K00029 - 1.1.1.40 9.567e-307 957.0
WH2_k127_4506164_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.965e-280 869.0
WH2_k127_4506164_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 513.0
WH2_k127_4506164_11 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 438.0
WH2_k127_4506164_12 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 426.0
WH2_k127_4506164_13 COG0303 Molybdopterin biosynthesis enzyme K03750 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 421.0
WH2_k127_4506164_14 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 353.0
WH2_k127_4506164_15 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 362.0
WH2_k127_4506164_16 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 354.0
WH2_k127_4506164_17 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 321.0
WH2_k127_4506164_18 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 314.0
WH2_k127_4506164_19 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 306.0
WH2_k127_4506164_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.392e-230 719.0
WH2_k127_4506164_20 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 315.0
WH2_k127_4506164_21 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 317.0
WH2_k127_4506164_22 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 308.0
WH2_k127_4506164_23 COG0512 Anthranilate para-aminobenzoate synthases component II K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 296.0
WH2_k127_4506164_24 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 285.0
WH2_k127_4506164_25 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003421 263.0
WH2_k127_4506164_26 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007908 265.0
WH2_k127_4506164_27 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000004971 233.0
WH2_k127_4506164_28 protein conserved in bacteria K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000008081 244.0
WH2_k127_4506164_29 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001629 217.0
WH2_k127_4506164_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.776e-217 681.0
WH2_k127_4506164_30 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000001484 210.0
WH2_k127_4506164_31 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.00000000000000000000000000000000000000000000000000000002408 205.0
WH2_k127_4506164_32 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000001711 203.0
WH2_k127_4506164_33 COG0784 FOG CheY-like receiver - - - 0.0000000000000000000000000000000000000000000000000000006331 202.0
WH2_k127_4506164_34 COG1279 Lysine efflux permease K06895 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - 0.00000000000000000000000000000000000000000000000002209 185.0
WH2_k127_4506164_35 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000001719 183.0
WH2_k127_4506164_36 Inositol hexakisphosphate - - - 0.00000000000000000000000000000000000000003562 169.0
WH2_k127_4506164_37 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000001167 160.0
WH2_k127_4506164_38 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000006947 131.0
WH2_k127_4506164_39 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000000000000000000000000001255 122.0
WH2_k127_4506164_4 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 1.03e-212 666.0
WH2_k127_4506164_40 - - - - 0.000000000000000000000000002862 117.0
WH2_k127_4506164_41 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000001748 113.0
WH2_k127_4506164_42 Septum formation initiator - - - 0.00000000000000000000002166 103.0
WH2_k127_4506164_43 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.0000000000000000000004948 98.0
WH2_k127_4506164_44 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000000261 96.0
WH2_k127_4506164_45 - - - - 0.00000000000000001246 89.0
WH2_k127_4506164_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.405e-208 658.0
WH2_k127_4506164_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 8.706e-202 636.0
WH2_k127_4506164_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 624.0
WH2_k127_4506164_8 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 610.0
WH2_k127_4506164_9 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 565.0
WH2_k127_4522501_0 Type I restriction enzyme R protein N terminus (HSDR_N) K01153 - 3.1.21.3 0.0 1551.0
WH2_k127_4522501_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03427 - 2.1.1.72 0.0 1159.0
WH2_k127_4522501_10 Protein of unknown function (DUF1488) - - - 0.00000000000000000007828 96.0
WH2_k127_4522501_11 - - - - 0.000000000000000001023 89.0
WH2_k127_4522501_2 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 558.0
WH2_k127_4522501_3 COG0732 Restriction endonuclease S subunits K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 440.0
WH2_k127_4522501_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 417.0
WH2_k127_4522501_5 Domain of unknown function (DUF4433) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 338.0
WH2_k127_4522501_6 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000004182 236.0
WH2_k127_4522501_7 - - - - 0.00000000000000000000000000000001365 130.0
WH2_k127_4522501_8 TfoX, N-terminal domain protein K07343 - - 0.0000000000000000000000000001738 119.0
WH2_k127_4540462_0 PFAM HipA domain protein K07154 - 2.7.11.1 1.379e-215 676.0
WH2_k127_4540462_1 protein related to capsule biosynthesis enzymes K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 539.0
WH2_k127_4540462_10 Belongs to the UPF0758 family K03630 - - 0.0000000000000000002131 95.0
WH2_k127_4540462_11 SMART Tetratricopeptide domain protein - - - 0.00000000000000001044 94.0
WH2_k127_4540462_12 sequence-specific DNA binding K07726 - - 0.000000000003905 72.0
WH2_k127_4540462_13 - - - - 0.00000000002082 70.0
WH2_k127_4540462_15 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0006629 48.0
WH2_k127_4540462_2 Domain of unknown function (DUF4942) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 432.0
WH2_k127_4540462_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000004066 177.0
WH2_k127_4540462_5 - - - - 0.000000000000000000000000000000001299 140.0
WH2_k127_4540462_6 Transcriptional regulator K07726 - - 0.000000000000000000000000000000001969 136.0
WH2_k127_4540462_7 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.000000000000000000000000000000002297 143.0
WH2_k127_4540462_8 Transcriptional Regulator, XRE family - - - 0.000000000000000000000000001648 119.0
WH2_k127_4540462_9 Initiator Replication protein - - - 0.000000000000000000003846 107.0
WH2_k127_4550454_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0 1590.0
WH2_k127_4550454_1 COG2873 O-acetylhomoserine sulfhydrylase - - - 1.078e-214 675.0
WH2_k127_4550454_10 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000003911 241.0
WH2_k127_4550454_11 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001395 211.0
WH2_k127_4550454_12 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000343 212.0
WH2_k127_4550454_13 Gram-negative porin K08720 - - 0.0000000000000000000000000000000000000000000000000000000005291 219.0
WH2_k127_4550454_14 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.0000000000000000000000000000000000000000000000000003058 192.0
WH2_k127_4550454_15 ISXO2-like transposase domain K07488 - - 0.000000000000000000000000000000000000000000000003189 182.0
WH2_k127_4550454_16 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000008542 175.0
WH2_k127_4550454_17 LysE type translocator - - - 0.00000000000000000000000000000000000000000008372 169.0
WH2_k127_4550454_18 High-affinity nickel-transport protein K08970 - - 0.0000000000000000000000000000000000000003657 163.0
WH2_k127_4550454_19 transport system, periplasmic component - - - 0.00000000000000000000000000000001343 134.0
WH2_k127_4550454_2 histidine kinase HAMP region domain protein K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 510.0
WH2_k127_4550454_20 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000000003079 122.0
WH2_k127_4550454_21 Protein of unknown function (DUF1192) - - - 0.0005136 48.0
WH2_k127_4550454_3 lysyl-tRNA synthetase K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 466.0
WH2_k127_4550454_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 439.0
WH2_k127_4550454_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000034 297.0
WH2_k127_4550454_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001463 275.0
WH2_k127_4550454_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005996 263.0
WH2_k127_4550454_8 protein conserved in bacteria K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000569 259.0
WH2_k127_4550454_9 transduction histidine kinase K07716 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005492 266.0
WH2_k127_4585758_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1074.0
WH2_k127_4585758_1 This protein is involved in the repair of mismatches in DNA K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 448.0
WH2_k127_4591531_0 Tim44 - - - 0.000000000000000000000000000000000000000000000001343 183.0
WH2_k127_4591531_1 Glycosyltransferase like family - - - 0.0000000000000000000000000000000000000000000004994 187.0
WH2_k127_4591531_2 Uracil-DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000131 175.0
WH2_k127_4591531_3 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000001051 112.0
WH2_k127_4591531_6 - - - - 0.0000001147 57.0
WH2_k127_4598661_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02056,K10441,K17210 - 3.6.3.17 1.826e-250 781.0
WH2_k127_4598661_1 Branched-chain amino acid transport system / permease component K02057 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 510.0
WH2_k127_4598661_2 Branched-chain amino acid transport system / permease component K02057 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 507.0
WH2_k127_4598661_3 Belongs to the IlvD Edd family K13875 - 4.2.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 398.0
WH2_k127_4598661_4 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 354.0
WH2_k127_4634281_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 523.0
WH2_k127_4634281_1 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 293.0
WH2_k127_4634281_2 WHG domain - - - 0.000000000000000000000000000000000000000000000000003251 198.0
WH2_k127_4634281_3 COG2131 Deoxycytidylate deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000001854 156.0
WH2_k127_4634281_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000002655 86.0
WH2_k127_4740974_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 555.0
WH2_k127_4740974_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 534.0
WH2_k127_4740974_2 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 450.0
WH2_k127_4740974_3 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 376.0
WH2_k127_4740974_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 340.0
WH2_k127_4740974_5 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 312.0
WH2_k127_4740974_6 transcriptional regulator - - - 0.000000000000000000000000001536 120.0
WH2_k127_4740974_7 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000000002994 100.0
WH2_k127_4740974_8 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000000007329 93.0
WH2_k127_4740974_9 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000005208 94.0
WH2_k127_4781042_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1069.0
WH2_k127_4781042_1 Mechanosensitive ion channel K22044 - - 2.549e-207 670.0
WH2_k127_4781042_10 COG2199 FOG GGDEF domain K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000003984 249.0
WH2_k127_4781042_11 Belongs to the Fur family K09826 - - 0.0000000000000000000000000000000000000000000000000000002592 197.0
WH2_k127_4781042_12 OsmC-like protein - - - 0.000000000000000000000000002441 117.0
WH2_k127_4781042_13 Alpha beta hydrolase - - - 0.000000000000001158 88.0
WH2_k127_4781042_2 Belongs to the beta-ketoacyl-ACP synthases family K00647 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 557.0
WH2_k127_4781042_3 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 511.0
WH2_k127_4781042_4 Transmembrane secretion effector K08169 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 508.0
WH2_k127_4781042_5 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 424.0
WH2_k127_4781042_6 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 378.0
WH2_k127_4781042_7 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 360.0
WH2_k127_4781042_8 PFAM GCN5-related N-acetyltransferase K00657 - 2.3.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 315.0
WH2_k127_4781042_9 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 293.0
WH2_k127_4799769_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05559,K05565 - - 0.0 1311.0
WH2_k127_4799769_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.08e-291 914.0
WH2_k127_4799769_10 DeoR C terminal sensor domain K02444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001141 253.0
WH2_k127_4799769_11 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000003703 248.0
WH2_k127_4799769_12 antiporter K05562 - - 0.0000000000000000000000000000000000000000000000001872 181.0
WH2_k127_4799769_13 Multisubunit Na H antiporter, MnhC subunit K05560 - - 0.00000000000000000000000000000000000000000000007906 179.0
WH2_k127_4799769_14 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000002128 169.0
WH2_k127_4799769_15 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000002541 150.0
WH2_k127_4799769_16 Na+/H+ antiporter subunit K05564 - - 0.0000000000000000000000000000000003076 139.0
WH2_k127_4799769_17 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05563 - - 0.00000000000000000000000000000009435 135.0
WH2_k127_4799769_18 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) - - - 0.000000000000000000000000000006224 125.0
WH2_k127_4799769_19 surface antigen - - - 0.00000000000112 73.0
WH2_k127_4799769_2 COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05561,K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 619.0
WH2_k127_4799769_20 This family consists of several bacterial proteins of K11903 - - 0.00003149 46.0
WH2_k127_4799769_3 PFAM extracellular solute-binding protein family 1 K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 537.0
WH2_k127_4799769_4 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 507.0
WH2_k127_4799769_5 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 492.0
WH2_k127_4799769_6 Acyl-CoA dehydrogenase, C-terminal domain K06446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 450.0
WH2_k127_4799769_7 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 442.0
WH2_k127_4799769_8 COG3842 ABC-type spermidine putrescine transport systems, ATPase components K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 402.0
WH2_k127_4799769_9 COG1177 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 341.0
WH2_k127_4804676_0 multicopper oxidase type 3 K22348 - 1.16.3.3 2.424e-222 709.0
WH2_k127_4804676_1 Pfam Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 451.0
WH2_k127_4804676_10 Copper binding periplasmic protein CusF - - - 0.0000000000000000003047 92.0
WH2_k127_4804676_11 - - - - 0.000000000000000005816 90.0
WH2_k127_4804676_12 oxidoreductase K06940 - - 0.00000000000007311 80.0
WH2_k127_4804676_13 - - - - 0.0000000001204 69.0
WH2_k127_4804676_14 - - - - 0.000000001481 62.0
WH2_k127_4804676_16 - - - - 0.000001311 56.0
WH2_k127_4804676_17 Cro Cl family transcriptional regulator - - - 0.000003833 55.0
WH2_k127_4804676_18 Ataxin-2 C-terminal region K11841,K13958 GO:0000731,GO:0002039,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004843,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005768,GO:0005769,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006464,GO:0006508,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008593,GO:0009058,GO:0009059,GO:0009894,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010506,GO:0010646,GO:0010647,GO:0010648,GO:0012505,GO:0016579,GO:0016787,GO:0018130,GO:0019222,GO:0019438,GO:0019538,GO:0019783,GO:0019985,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030330,GO:0031323,GO:0031329,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0032991,GO:0033554,GO:0034097,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0036211,GO:0036459,GO:0042221,GO:0042770,GO:0043122,GO:0043124,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044325,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045747,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0070013,GO:0070555,GO:0070646,GO:0070647,GO:0070887,GO:0071310,GO:0071345,GO:0071347,GO:0071704,GO:0071897,GO:0072331,GO:0090304,GO:0097708,GO:0101005,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1902531,GO:1902532 3.4.19.12 0.0008007 44.0
WH2_k127_4804676_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 336.0
WH2_k127_4804676_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 301.0
WH2_k127_4804676_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000002753 222.0
WH2_k127_4804676_5 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000000000000001873 165.0
WH2_k127_4804676_6 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000003662 151.0
WH2_k127_4804676_7 - - - - 0.00000000000000000000000005608 110.0
WH2_k127_4804676_8 Resolvase, N terminal domain - - - 0.000000000000000000000000555 109.0
WH2_k127_4804676_9 Transglycosylase SLT domain - - - 0.0000000000000000000002882 101.0
WH2_k127_4888350_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01535,K12955 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2,3.6.3.6 1.709e-294 927.0
WH2_k127_4888350_1 Peptidase family M41 K03798 - - 1.441e-240 758.0
WH2_k127_4888350_10 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 428.0
WH2_k127_4888350_11 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 407.0
WH2_k127_4888350_12 Putative beta-barrel porin 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 360.0
WH2_k127_4888350_13 COGs COG2148 Sugar transferase involved in lipopolysaccharide synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 357.0
WH2_k127_4888350_14 KR domain K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 317.0
WH2_k127_4888350_15 Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 312.0
WH2_k127_4888350_16 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 304.0
WH2_k127_4888350_17 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 305.0
WH2_k127_4888350_18 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002128 291.0
WH2_k127_4888350_19 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001692 287.0
WH2_k127_4888350_2 ABC-type multidrug transport system ATPase component K13926 - - 9.119e-217 686.0
WH2_k127_4888350_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006644 265.0
WH2_k127_4888350_21 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001732 260.0
WH2_k127_4888350_22 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001286 246.0
WH2_k127_4888350_23 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001846 261.0
WH2_k127_4888350_24 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002241 249.0
WH2_k127_4888350_25 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000233 243.0
WH2_k127_4888350_26 Belongs to the ABC transporter superfamily K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000002961 256.0
WH2_k127_4888350_27 COG1596 Periplasmic protein involved in polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000001016 238.0
WH2_k127_4888350_28 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000002293 228.0
WH2_k127_4888350_29 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000006443 224.0
WH2_k127_4888350_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 565.0
WH2_k127_4888350_30 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000000000006245 208.0
WH2_k127_4888350_31 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000003601 206.0
WH2_k127_4888350_32 Universal stress protein UspA - - - 0.0000000000000000000000000000000000000000000000000000004938 205.0
WH2_k127_4888350_33 transferase activity, transferring glycosyl groups K19424 GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 - 0.000000000000000000000000000000000000000000000000000009597 203.0
WH2_k127_4888350_34 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000002054 193.0
WH2_k127_4888350_35 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000005058 198.0
WH2_k127_4888350_36 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000001589 184.0
WH2_k127_4888350_37 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000000000000005175 169.0
WH2_k127_4888350_38 Universal stress protein - - - 0.000000000000000000000000000000000000000005869 168.0
WH2_k127_4888350_39 - - - - 0.00000000000000000000000000000000000000008299 155.0
WH2_k127_4888350_4 ATP-grasp domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 582.0
WH2_k127_4888350_40 Universal stress protein family - - - 0.0000000000000000000000000000000000000002543 161.0
WH2_k127_4888350_41 Universal stress protein - - - 0.000000000000000000000000000000000000003 158.0
WH2_k127_4888350_42 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000371 154.0
WH2_k127_4888350_43 Universal stress protein - - - 0.0000000000000000000000000000000003514 147.0
WH2_k127_4888350_44 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000007026 136.0
WH2_k127_4888350_45 polysaccharide deacetylase - - - 0.0000000000000000000000003508 116.0
WH2_k127_4888350_46 - - - - 0.000000000000000000000008309 115.0
WH2_k127_4888350_47 Polysaccharide deacetylase - - - 0.0000000000005721 79.0
WH2_k127_4888350_48 - - - - 0.0000000003141 66.0
WH2_k127_4888350_49 PFAM Glycosyl transferase, group 1 K14335 - - 0.00000009778 65.0
WH2_k127_4888350_5 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 482.0
WH2_k127_4888350_50 - - - - 0.0000002849 61.0
WH2_k127_4888350_51 methyltransferase - - - 0.0000006388 61.0
WH2_k127_4888350_52 Methyltransferase domain - - - 0.000001561 61.0
WH2_k127_4888350_53 Cytochrome c - - - 0.000004185 57.0
WH2_k127_4888350_54 Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system K02013 - 3.6.3.34 0.00001201 59.0
WH2_k127_4888350_6 Chain length determinant protein K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 489.0
WH2_k127_4888350_7 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 464.0
WH2_k127_4888350_8 abc transporter, ATP-binding protein K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 473.0
WH2_k127_4888350_9 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 452.0
WH2_k127_4948128_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 1.576e-220 709.0
WH2_k127_4948128_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 461.0
WH2_k127_4948128_2 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 455.0
WH2_k127_4948128_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 397.0
WH2_k127_4948128_4 Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 289.0
WH2_k127_4948128_5 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
WH2_k127_4948128_6 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000001905 130.0
WH2_k127_4948128_7 amine dehydrogenase activity - - - 0.000001176 62.0
WH2_k127_4948128_8 Bacterial Ig-like domain (group 2) - - - 0.00002449 58.0
WH2_k127_4969673_0 dihydroxy-acid dehydratase activity K01687 - 4.2.1.9 0.0 1038.0
WH2_k127_4969673_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.245e-313 970.0
WH2_k127_4969673_2 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 541.0
WH2_k127_4969673_3 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 442.0
WH2_k127_4969673_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000002743 235.0
WH2_k127_4969673_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000008534 201.0
WH2_k127_4969673_6 Endoribonuclease L-PSP - - - 0.000000000000000000000000000001239 124.0
WH2_k127_4972077_0 Glycosyl transferase family group 2 - - - 7.498e-300 942.0
WH2_k127_4972077_1 Belongs to the ABC transporter superfamily K13896 - - 2.159e-221 711.0
WH2_k127_4972077_10 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 481.0
WH2_k127_4972077_11 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 441.0
WH2_k127_4972077_12 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
WH2_k127_4972077_13 beta (1-6) glucans synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 402.0
WH2_k127_4972077_14 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 347.0
WH2_k127_4972077_15 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 328.0
WH2_k127_4972077_16 Tat pathway signal sequence domain-containing protein 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 334.0
WH2_k127_4972077_17 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 332.0
WH2_k127_4972077_18 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 329.0
WH2_k127_4972077_19 dehydrogenase and related dehydrogenases K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 321.0
WH2_k127_4972077_2 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 1.537e-199 638.0
WH2_k127_4972077_20 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 294.0
WH2_k127_4972077_21 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006629 278.0
WH2_k127_4972077_22 Pas domain K03320,K11525 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001782 286.0
WH2_k127_4972077_23 Belongs to the Nudix hydrolase family K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001468 275.0
WH2_k127_4972077_24 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002073 261.0
WH2_k127_4972077_25 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000003712 225.0
WH2_k127_4972077_26 Cytochrome c K08738 - - 0.0000000000000000000000000000000000000000000005827 171.0
WH2_k127_4972077_27 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000001993 168.0
WH2_k127_4972077_28 Formyl transferase - - - 0.000000000000000000000000000000000000000005902 162.0
WH2_k127_4972077_29 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000009613 151.0
WH2_k127_4972077_3 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 586.0
WH2_k127_4972077_30 - - - - 0.000000000000000000000000000000000000001954 154.0
WH2_k127_4972077_31 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000001419 139.0
WH2_k127_4972077_32 Histidine triad (HIT) protein - - - 0.000000000000000000000000000000000006638 140.0
WH2_k127_4972077_33 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000002056 143.0
WH2_k127_4972077_34 Ribosomal prokaryotic L21 protein K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000006324 136.0
WH2_k127_4972077_35 Sugar efflux transporter for intercellular exchange K15383 - - 0.00000000000000000000004341 107.0
WH2_k127_4972077_36 Protein of unknown function (DUF1491) - - - 0.0000000000000000000005243 108.0
WH2_k127_4972077_4 transport system, permease component K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 563.0
WH2_k127_4972077_5 transport system, permease component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 555.0
WH2_k127_4972077_6 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 545.0
WH2_k127_4972077_7 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 527.0
WH2_k127_4972077_8 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 504.0
WH2_k127_4972077_9 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 489.0
WH2_k127_4988680_0 His Kinase A (phosphoacceptor) domain - - - 5.492e-311 977.0
WH2_k127_4988680_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 2.028e-261 816.0
WH2_k127_4988680_10 LexA-binding, inner membrane-associated putative hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000001687 227.0
WH2_k127_4988680_11 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000007483 222.0
WH2_k127_4988680_12 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000009769 171.0
WH2_k127_4988680_13 Endoribonuclease L-PSP - - - 0.000000000000000000000000000001171 125.0
WH2_k127_4988680_14 Ribonuclease B OB domain K03704 - - 0.0000000000000000000000000001886 115.0
WH2_k127_4988680_15 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000002121 105.0
WH2_k127_4988680_16 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000004671 80.0
WH2_k127_4988680_2 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 1.908e-248 782.0
WH2_k127_4988680_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 359.0
WH2_k127_4988680_4 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 359.0
WH2_k127_4988680_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 338.0
WH2_k127_4988680_6 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 332.0
WH2_k127_4988680_7 Acetyltransferases including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003436 284.0
WH2_k127_4988680_8 Nitroreductase family K04719 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016491,GO:0016705,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79 0.000000000000000000000000000000000000000000000000000000000000000000000000002143 276.0
WH2_k127_4988680_9 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000004579 218.0
WH2_k127_5005456_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 7.579e-228 715.0
WH2_k127_5005456_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000004143 218.0
WH2_k127_5005456_2 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000001616 174.0
WH2_k127_5005456_3 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.00000000000000000000000000000000000000001354 162.0
WH2_k127_5005456_4 Domain of unknown function (DUF4170) - - - 0.000000000132 70.0
WH2_k127_5007639_0 Belongs to the thiolase family K00626,K07508 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 456.0
WH2_k127_5007639_1 membrane protein, terc - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 369.0
WH2_k127_5007639_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 348.0
WH2_k127_5007639_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002617 301.0
WH2_k127_5007639_4 DNA alkylation repair - - - 0.00000000000000000000000000000000000000008417 154.0
WH2_k127_5054954_0 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006891 430.0
WH2_k127_5054954_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 352.0
WH2_k127_5054954_2 Etoposide-induced protein 2.4 (EI24) - - - 0.0000000000000000000000000000000000000000000000022 182.0
WH2_k127_5054954_3 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000002084 148.0
WH2_k127_5054954_4 Voltage gated chloride channel - - - 0.0000000000000000002103 96.0
WH2_k127_5054954_5 - - - - 0.00004346 52.0
WH2_k127_5058171_0 AMP-binding enzyme C-terminal domain K18661 - - 1.222e-224 718.0
WH2_k127_5058171_1 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 550.0
WH2_k127_5058171_10 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000003587 242.0
WH2_k127_5058171_11 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000004787 247.0
WH2_k127_5058171_12 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000001457 236.0
WH2_k127_5058171_13 FCD - - - 0.00000000000000000000000000000000006604 137.0
WH2_k127_5058171_14 KR domain - - - 0.000000000000000000000000000000001881 132.0
WH2_k127_5058171_2 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 516.0
WH2_k127_5058171_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 510.0
WH2_k127_5058171_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 495.0
WH2_k127_5058171_5 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 362.0
WH2_k127_5058171_6 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 336.0
WH2_k127_5058171_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 309.0
WH2_k127_5058171_8 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001087 284.0
WH2_k127_5058171_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005859 287.0
WH2_k127_5062939_0 Helicase K03724 - - 0.0 1032.0
WH2_k127_5062939_1 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 437.0
WH2_k127_5062939_10 Sel1-like repeats. K07126 - - 0.000000001975 69.0
WH2_k127_5062939_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001835 293.0
WH2_k127_5062939_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002646 280.0
WH2_k127_5062939_4 Calcineurin-like phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001398 274.0
WH2_k127_5062939_5 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001641 275.0
WH2_k127_5062939_6 17 kDa outer membrane surface antigen - - - 0.00000000000000000000000000000000000000000000000000838 187.0
WH2_k127_5062939_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000003305 139.0
WH2_k127_5062939_8 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000001163 121.0
WH2_k127_5062939_9 - - - - 0.00000000000003222 78.0
WH2_k127_5086057_0 single-stranded-DNA-specific exonuclease recJ K07462 - - 8.874e-227 719.0
WH2_k127_5086057_1 PhoD-like phosphatase K01113 - 3.1.3.1 7.192e-218 689.0
WH2_k127_5086057_10 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 379.0
WH2_k127_5086057_11 Molybdate ABC transporter K02018 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 343.0
WH2_k127_5086057_12 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 291.0
WH2_k127_5086057_13 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002569 291.0
WH2_k127_5086057_14 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000003862 222.0
WH2_k127_5086057_15 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000037 192.0
WH2_k127_5086057_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000001784 102.0
WH2_k127_5086057_17 - - - - 0.00000000000000000234 87.0
WH2_k127_5086057_19 OmpA family - - - 0.0005558 48.0
WH2_k127_5086057_2 histidine ammonia-lyase activity K01745 - 4.3.1.3 2.246e-195 622.0
WH2_k127_5086057_3 Aminotransferase K14261 - - 2.529e-194 621.0
WH2_k127_5086057_4 PFAM Alcohol dehydrogenase zinc-binding domain protein K00001,K07119 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 535.0
WH2_k127_5086057_5 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 527.0
WH2_k127_5086057_6 COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins K11532 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 445.0
WH2_k127_5086057_7 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 454.0
WH2_k127_5086057_8 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009786 442.0
WH2_k127_5086057_9 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 381.0
WH2_k127_5091160_0 Rieske [2Fe-2S] domain - - - 1.225e-226 709.0
WH2_k127_5091160_1 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 2.089e-217 693.0
WH2_k127_5091160_2 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 533.0
WH2_k127_5091160_3 Extracellular liganD-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 517.0
WH2_k127_5091160_4 Aldose 1-epimerase K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000002099 218.0
WH2_k127_5091160_5 ETC complex I subunit - - - 0.0000000000000000000000000001983 119.0
WH2_k127_5091160_6 - - - - 0.00000000000000000000007401 114.0
WH2_k127_5091160_7 - - - - 0.0000000000000000696 82.0
WH2_k127_5091160_8 Glycosyl transferase family 41 - - - 0.00006355 52.0
WH2_k127_5130623_0 Belongs to the GcvT family K00314 - 1.5.8.3 0.0 1630.0
WH2_k127_5130623_1 Amidase K02433 - 6.3.5.6,6.3.5.7 1.285e-231 723.0
WH2_k127_5130623_10 COG3639 ABC-type phosphate phosphonate transport system, permease component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 431.0
WH2_k127_5130623_11 Belongs to the heme-copper respiratory oxidase family K02298 - 1.10.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 403.0
WH2_k127_5130623_12 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 413.0
WH2_k127_5130623_13 Enoyl-(Acyl carrier protein) reductase K00023,K00059,K07535 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 387.0
WH2_k127_5130623_14 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 387.0
WH2_k127_5130623_15 Bacterial transferase hexapeptide (six repeats) K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 349.0
WH2_k127_5130623_16 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 344.0
WH2_k127_5130623_17 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 293.0
WH2_k127_5130623_18 Proton-conducting membrane transporter - - - 0.00000000000000000000000000000003627 125.0
WH2_k127_5130623_19 Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) K05774 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006015,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019693,GO:0033863,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046496,GO:0046835,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.23 0.00000000003419 66.0
WH2_k127_5130623_2 Sugar (and other) transporter - - - 3.477e-218 687.0
WH2_k127_5130623_3 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 588.0
WH2_k127_5130623_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02049,K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 556.0
WH2_k127_5130623_5 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 547.0
WH2_k127_5130623_6 cytochrome c oxidase subunit II K02297 - 1.10.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 552.0
WH2_k127_5130623_7 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 534.0
WH2_k127_5130623_8 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 497.0
WH2_k127_5130623_9 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 478.0
WH2_k127_5158563_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 614.0
WH2_k127_5158563_1 MarR family - - - 0.00000000000000000004961 96.0
WH2_k127_5158563_2 EF-hand domain pair - - - 0.000000000000007534 83.0
WH2_k127_5158563_3 Heavy-metal resistance - - - 0.0001088 53.0
WH2_k127_5162736_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.0 1108.0
WH2_k127_5162736_1 N-methylhydantoinase B acetone carboxylase alpha subunit - - - 4.195e-294 911.0
WH2_k127_5162736_10 Ferritin-like domain K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001477 277.0
WH2_k127_5162736_11 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001882 278.0
WH2_k127_5162736_12 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005686 263.0
WH2_k127_5162736_13 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009459 265.0
WH2_k127_5162736_14 Abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000001586 223.0
WH2_k127_5162736_15 Cupin 2, conserved barrel domain protein K14670,K14673 - - 0.0000000000000000000000000000000000000000000000000000006075 195.0
WH2_k127_5162736_2 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 575.0
WH2_k127_5162736_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 477.0
WH2_k127_5162736_4 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 444.0
WH2_k127_5162736_5 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 362.0
WH2_k127_5162736_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 339.0
WH2_k127_5162736_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 347.0
WH2_k127_5162736_8 COG3264 Small-conductance mechanosensitive channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 348.0
WH2_k127_5162736_9 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001215 282.0
WH2_k127_5162744_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.126e-303 944.0
WH2_k127_5162744_1 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 7.157e-258 810.0
WH2_k127_5162744_10 TOBE domain K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 462.0
WH2_k127_5162744_11 transport system periplasmic component K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 460.0
WH2_k127_5162744_12 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 450.0
WH2_k127_5162744_13 Belongs to the binding-protein-dependent transport system permease family K05832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 445.0
WH2_k127_5162744_14 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 441.0
WH2_k127_5162744_15 Dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 433.0
WH2_k127_5162744_16 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 421.0
WH2_k127_5162744_17 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 426.0
WH2_k127_5162744_18 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 395.0
WH2_k127_5162744_19 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 381.0
WH2_k127_5162744_2 Bacterial extracellular solute-binding protein K02055 - - 1.336e-250 778.0
WH2_k127_5162744_20 ABC transporter K05833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 347.0
WH2_k127_5162744_21 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 362.0
WH2_k127_5162744_22 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 346.0
WH2_k127_5162744_23 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 334.0
WH2_k127_5162744_24 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 335.0
WH2_k127_5162744_25 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 312.0
WH2_k127_5162744_26 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 327.0
WH2_k127_5162744_27 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 296.0
WH2_k127_5162744_28 Bacterial transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000017 286.0
WH2_k127_5162744_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007195 268.0
WH2_k127_5162744_3 TIGRFAM type VI secretion ATPase, ClpV1 family K11907 - - 1.703e-241 764.0
WH2_k127_5162744_30 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002191 253.0
WH2_k127_5162744_31 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008906 238.0
WH2_k127_5162744_32 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000006069 231.0
WH2_k127_5162744_33 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000002046 226.0
WH2_k127_5162744_34 PFAM Asp Glu hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000001558 219.0
WH2_k127_5162744_35 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000001452 216.0
WH2_k127_5162744_36 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000001128 180.0
WH2_k127_5162744_37 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000003957 186.0
WH2_k127_5162744_38 Rhs element Vgr protein K11904 - - 0.0000000000000000000000000000000000000004708 169.0
WH2_k127_5162744_39 Domain of unknown function (DUF4150) - - - 0.000000000000000000000000000000000005987 141.0
WH2_k127_5162744_4 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 4.475e-225 703.0
WH2_k127_5162744_40 Protein of unknown function (DUF3540) - - - 0.00000000000000005213 91.0
WH2_k127_5162744_41 protein homooligomerization K21919 - - 0.000000000001332 82.0
WH2_k127_5162744_5 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 563.0
WH2_k127_5162744_6 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 565.0
WH2_k127_5162744_7 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 543.0
WH2_k127_5162744_8 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 521.0
WH2_k127_5162744_9 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 463.0
WH2_k127_5165113_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 508.0
WH2_k127_5165113_1 Formyl transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 507.0
WH2_k127_5165113_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 460.0
WH2_k127_5165113_3 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 439.0
WH2_k127_5165113_4 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 352.0
WH2_k127_5165113_5 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009322 282.0
WH2_k127_5165113_6 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000003141 267.0
WH2_k127_5165113_7 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000000000000000000513 166.0
WH2_k127_5165113_8 permeases of the major facilitator superfamily K07552 - - 0.000132 48.0
WH2_k127_5219766_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 381.0
WH2_k127_5219766_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 344.0
WH2_k127_5219766_2 COG0659 Sulfate permease and related transporters (MFS superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 328.0
WH2_k127_5219766_3 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 311.0
WH2_k127_5219766_4 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009668 244.0
WH2_k127_5219766_5 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000005887 237.0
WH2_k127_5219766_6 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000004913 155.0
WH2_k127_5219766_7 - - - - 0.0000000000000000007861 97.0
WH2_k127_5219766_8 Protein of unknown function (DUF1109) - - - 0.0000006155 51.0
WH2_k127_5235878_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.571e-238 767.0
WH2_k127_5235878_1 Acetylornithine deacetylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 554.0
WH2_k127_5235878_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 470.0
WH2_k127_5235878_3 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 376.0
WH2_k127_5235878_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 336.0
WH2_k127_5235878_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 326.0
WH2_k127_5235878_6 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000136 186.0
WH2_k127_5307500_0 drug resistance transporter, Bcr CflA K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 520.0
WH2_k127_5307500_1 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 471.0
WH2_k127_5307500_10 DoxX-like family - - - 0.000000000000000000000000000000000001001 159.0
WH2_k127_5307500_11 PFAM thioesterase superfamily - - - 0.0000000000000000000000000008457 118.0
WH2_k127_5307500_12 Cold shock K03704 - - 0.000000000000000000000001124 107.0
WH2_k127_5307500_2 Drug resistance transporter Bcr CflA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 343.0
WH2_k127_5307500_3 7TM diverse intracellular signalling - - - 0.000000000000000000000000000000000000000000000000000000000000000003463 247.0
WH2_k127_5307500_4 Belongs to the ArsC family - - - 0.0000000000000000000000000000000000000000000000000005518 187.0
WH2_k127_5307500_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000005265 190.0
WH2_k127_5307500_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000004563 167.0
WH2_k127_5307500_7 Cold shock protein domain K03704 - - 0.000000000000000000000000000000000000000002644 164.0
WH2_k127_5307500_8 PFAM Cupin 2 conserved barrel domain protein K11312 - - 0.000000000000000000000000000000000000005314 148.0
WH2_k127_5307500_9 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000008524 157.0
WH2_k127_5329688_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1239.0
WH2_k127_5329688_1 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 5.985e-307 957.0
WH2_k127_5329688_10 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 443.0
WH2_k127_5329688_11 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 439.0
WH2_k127_5329688_12 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 453.0
WH2_k127_5329688_13 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 338.0
WH2_k127_5329688_14 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 324.0
WH2_k127_5329688_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 316.0
WH2_k127_5329688_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 300.0
WH2_k127_5329688_17 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 294.0
WH2_k127_5329688_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005164 279.0
WH2_k127_5329688_19 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001242 270.0
WH2_k127_5329688_2 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.502e-279 872.0
WH2_k127_5329688_20 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001769 275.0
WH2_k127_5329688_21 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003612 265.0
WH2_k127_5329688_22 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003453 268.0
WH2_k127_5329688_23 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000008589 219.0
WH2_k127_5329688_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000489 192.0
WH2_k127_5329688_25 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000004407 187.0
WH2_k127_5329688_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000003722 170.0
WH2_k127_5329688_27 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000006097 143.0
WH2_k127_5329688_28 - - - - 0.00000005794 53.0
WH2_k127_5329688_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 2.158e-250 776.0
WH2_k127_5329688_30 - - - - 0.0002017 51.0
WH2_k127_5329688_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.044e-238 743.0
WH2_k127_5329688_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 4.553e-208 651.0
WH2_k127_5329688_6 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 621.0
WH2_k127_5329688_7 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 567.0
WH2_k127_5329688_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 512.0
WH2_k127_5329688_9 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 512.0
WH2_k127_5339069_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 499.0
WH2_k127_5339069_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000568 228.0
WH2_k127_5339069_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000001191 196.0
WH2_k127_537456_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1356.0
WH2_k127_537456_1 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 557.0
WH2_k127_537456_10 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.00000000000000000000001277 116.0
WH2_k127_537456_11 polysaccharide deacetylase - - - 0.0000000000000000001059 98.0
WH2_k127_537456_12 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000008635 67.0
WH2_k127_537456_2 mandelate racemase muconate lactonizing K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 549.0
WH2_k127_537456_3 His Kinase A (phospho-acceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 387.0
WH2_k127_537456_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 395.0
WH2_k127_537456_5 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 368.0
WH2_k127_537456_6 MgtC family K07507 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 364.0
WH2_k127_537456_7 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 318.0
WH2_k127_537456_8 Flagellar hook protein FlgE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 325.0
WH2_k127_537456_9 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006116 280.0
WH2_k127_538630_0 Aldose 1-epimerase K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 318.0
WH2_k127_538630_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K22185 - 1.1.1.175 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 309.0
WH2_k127_538630_2 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002344 263.0
WH2_k127_538630_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000002195 241.0
WH2_k127_538630_4 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000001958 221.0
WH2_k127_538630_5 Isochorismatase family - - - 0.000000000000000000002683 102.0
WH2_k127_538630_6 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.000000007603 59.0
WH2_k127_540005_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 7.179e-303 933.0
WH2_k127_540005_1 PFAM extracellular solute-binding protein family 5 K02035 - - 2.319e-297 918.0
WH2_k127_540005_10 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 487.0
WH2_k127_540005_11 Belongs to the binding-protein-dependent transport system permease family K02057,K10440,K17214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 480.0
WH2_k127_540005_12 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 447.0
WH2_k127_540005_13 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 430.0
WH2_k127_540005_14 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 403.0
WH2_k127_540005_15 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 392.0
WH2_k127_540005_16 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 386.0
WH2_k127_540005_17 Belongs to the D-glutamate cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 377.0
WH2_k127_540005_18 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 288.0
WH2_k127_540005_19 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000282 289.0
WH2_k127_540005_2 FAD dependent oxidoreductase K00303 - 1.5.3.1 5.149e-242 751.0
WH2_k127_540005_20 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002155 283.0
WH2_k127_540005_21 branched-chain amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001527 278.0
WH2_k127_540005_22 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009126 266.0
WH2_k127_540005_23 aminopeptidase activity K18028 - 1.13.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000002036 254.0
WH2_k127_540005_24 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000003829 215.0
WH2_k127_540005_25 low-complexity proteins - - - 0.0000000000000000000000000000000000000000000000000000000004175 218.0
WH2_k127_540005_26 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.0000000000000000000000000000000000000000000000000000002524 199.0
WH2_k127_540005_27 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000000002316 183.0
WH2_k127_540005_28 Asp/Glu/Hydantoin racemase - - - 0.00000000000000000000000000000000000000000000001032 182.0
WH2_k127_540005_29 Sarcosine oxidase, delta subunit K00304 - 1.5.3.1 0.00000000000000000000000000000000000000000000001696 172.0
WH2_k127_540005_3 ABC transporter K02056,K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 584.0
WH2_k127_540005_30 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00000000000000000000000000000000000000000000006157 173.0
WH2_k127_540005_31 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000004993 158.0
WH2_k127_540005_4 2Fe-2S iron-sulfur cluster binding domain K00302,K22086 - 1.5.3.1,1.5.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 562.0
WH2_k127_540005_5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate K00899 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 561.0
WH2_k127_540005_6 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 537.0
WH2_k127_540005_7 ABC-type sugar transport system periplasmic component K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 520.0
WH2_k127_540005_8 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 522.0
WH2_k127_540005_9 UDP-N-acetylglucosamine 2-epimerase K01791,K08068 - 3.2.1.183,5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 487.0
WH2_k127_5421603_0 ABC-type dipeptide transport system periplasmic component - - - 4.303e-282 874.0
WH2_k127_5421603_1 FAD binding domain K22270 - 1.14.13.24 1.27e-196 619.0
WH2_k127_5421603_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 451.0
WH2_k127_5421603_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 403.0
WH2_k127_5421603_4 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004098 258.0
WH2_k127_5421603_5 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001481 245.0
WH2_k127_5470832_0 Cytochrome C and Quinol oxidase polypeptide I K02274,K15408 - 1.9.3.1 0.0 1140.0
WH2_k127_5470832_1 Belongs to the heme-copper respiratory oxidase family K02298 - 1.10.3.10 6.62e-275 848.0
WH2_k127_5470832_10 Bacterial regulatory protein, Fis family K15012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007614 278.0
WH2_k127_5470832_11 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351 - - 0.000000000000000000000000000000000000000000000000000000000000000000003808 244.0
WH2_k127_5470832_12 cytochrome C oxidase subunit IV K02300 - - 0.00000000000000000000000000000000000000000000002448 181.0
WH2_k127_5470832_13 Uncharacterised protein family (UPF0093) - - - 0.0000000000000000000000000000000000003806 150.0
WH2_k127_5470832_14 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000009083 101.0
WH2_k127_5470832_15 Domain of unknown function (DUF1330) - - - 0.0000000627 59.0
WH2_k127_5470832_16 zinc-finger binding domain of transposase IS66 K07484 - - 0.000005658 49.0
WH2_k127_5470832_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.23e-250 781.0
WH2_k127_5470832_3 Histidine kinase-like ATPases K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 607.0
WH2_k127_5470832_4 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 584.0
WH2_k127_5470832_5 Polyphosphate kinase 2 (PPK2) K22468 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 565.0
WH2_k127_5470832_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 563.0
WH2_k127_5470832_7 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 362.0
WH2_k127_5470832_8 SURF1 family K14998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 306.0
WH2_k127_5470832_9 Cytochrome C oxidase subunit II, periplasmic domain K02275,K02826 - 1.10.3.12,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 307.0
WH2_k127_5481339_0 Protein of unknown function (DUF3376) - - - 6.928e-214 691.0
WH2_k127_5481339_1 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 2.933e-201 647.0
WH2_k127_5481339_10 PFAM Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000006328 205.0
WH2_k127_5481339_11 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000007268 146.0
WH2_k127_5481339_12 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000003304 76.0
WH2_k127_5481339_13 Sporulation related domain - - - 0.000000000424 67.0
WH2_k127_5481339_14 beta-lactamase activity K07126 - - 0.0003865 49.0
WH2_k127_5481339_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596 - 4.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 591.0
WH2_k127_5481339_3 Polysaccharide biosynthesis protein K13013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 583.0
WH2_k127_5481339_4 Polysaccharide biosynthesis protein K13013,K15894 - 4.2.1.115 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 496.0
WH2_k127_5481339_5 Glycosyl transferase family 41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 468.0
WH2_k127_5481339_6 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 444.0
WH2_k127_5481339_7 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005887 286.0
WH2_k127_5481339_8 Cytidylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002489 257.0
WH2_k127_5481339_9 COG3980 Spore coat polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001141 245.0
WH2_k127_549899_0 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 468.0
WH2_k127_549899_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 461.0
WH2_k127_549899_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 351.0
WH2_k127_549899_3 Fe-S protein K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000001751 248.0
WH2_k127_549899_4 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000001151 240.0
WH2_k127_549899_5 TIGRFAM Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000002394 171.0
WH2_k127_549899_6 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000001588 166.0
WH2_k127_549899_7 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000007457 129.0
WH2_k127_549899_8 - - - - 0.000000000002115 74.0
WH2_k127_549899_9 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000001619 61.0
WH2_k127_5502799_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 521.0
WH2_k127_5502799_1 - - - - 0.000000000000000000000000000000000000000000000000000000000004296 214.0
WH2_k127_5502799_2 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000005001 182.0
WH2_k127_5502799_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000004584 184.0
WH2_k127_556225_0 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 462.0
WH2_k127_556225_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006897 376.0
WH2_k127_556225_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 304.0
WH2_k127_556225_11 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 302.0
WH2_k127_556225_12 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006408 280.0
WH2_k127_556225_13 Sulfotransferase family K01014 - 2.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001768 280.0
WH2_k127_556225_14 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004889 258.0
WH2_k127_556225_15 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001252 252.0
WH2_k127_556225_16 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001136 258.0
WH2_k127_556225_17 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004684 229.0
WH2_k127_556225_18 Gram-negative porin K08720 - - 0.000000000000000000000000000000000000000000000000000000000000001439 236.0
WH2_k127_556225_19 diguanylate cyclase - - - 0.0000000000000000000000007013 118.0
WH2_k127_556225_2 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 374.0
WH2_k127_556225_20 - - - - 0.000000000000000001685 98.0
WH2_k127_556225_21 Gram-negative porin K08720 - - 0.0000000478 61.0
WH2_k127_556225_3 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 - 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 401.0
WH2_k127_556225_4 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 377.0
WH2_k127_556225_5 ABC-type Mn2 Zn2 transport systems permease components K02075,K11606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 349.0
WH2_k127_556225_6 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 347.0
WH2_k127_556225_7 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 338.0
WH2_k127_556225_8 ATPases associated with a variety of cellular activities K02074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 322.0
WH2_k127_556225_9 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 318.0
WH2_k127_5607020_0 KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 490.0
WH2_k127_5607020_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 374.0
WH2_k127_5607020_10 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000007114 188.0
WH2_k127_5607020_11 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000001533 179.0
WH2_k127_5607020_12 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000001538 179.0
WH2_k127_5607020_13 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000008615 134.0
WH2_k127_5607020_14 Uncharacterized protein conserved in bacteria (DUF2076) K09945 - - 0.000000000006848 71.0
WH2_k127_5607020_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 299.0
WH2_k127_5607020_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 289.0
WH2_k127_5607020_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 293.0
WH2_k127_5607020_5 isochorismatase, hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000001914 224.0
WH2_k127_5607020_6 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001868 218.0
WH2_k127_5607020_7 PFAM regulatory protein AsnC Lrp family K03719 - - 0.000000000000000000000000000000000000000000000000000000003028 205.0
WH2_k127_5607020_8 transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000007687 203.0
WH2_k127_5607020_9 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000002202 197.0
WH2_k127_5623992_0 protein involved in outer membrane biogenesis K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 355.0
WH2_k127_5623992_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000007811 211.0
WH2_k127_5633769_0 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 632.0
WH2_k127_5633769_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 449.0
WH2_k127_5633769_2 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003169 281.0
WH2_k127_5633769_3 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000004322 153.0
WH2_k127_5661433_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 574.0
WH2_k127_5661433_1 signal transduction histidine kinase K13587 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 552.0
WH2_k127_5685547_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.0 1192.0
WH2_k127_5685547_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.592e-250 781.0
WH2_k127_5685547_10 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 536.0
WH2_k127_5685547_11 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 525.0
WH2_k127_5685547_12 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 515.0
WH2_k127_5685547_13 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 472.0
WH2_k127_5685547_14 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 458.0
WH2_k127_5685547_15 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 385.0
WH2_k127_5685547_16 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 364.0
WH2_k127_5685547_17 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 364.0
WH2_k127_5685547_18 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 349.0
WH2_k127_5685547_19 helix_turn_helix, arabinose operon control protein K18954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 337.0
WH2_k127_5685547_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.455e-225 704.0
WH2_k127_5685547_20 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 337.0
WH2_k127_5685547_21 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 314.0
WH2_k127_5685547_22 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003799 276.0
WH2_k127_5685547_23 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003964 265.0
WH2_k127_5685547_24 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004734 250.0
WH2_k127_5685547_25 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004434 231.0
WH2_k127_5685547_26 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000002075 219.0
WH2_k127_5685547_27 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000014 231.0
WH2_k127_5685547_28 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000001406 214.0
WH2_k127_5685547_29 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000002081 203.0
WH2_k127_5685547_3 FAD dependent oxidoreductase - - - 4.745e-217 680.0
WH2_k127_5685547_30 cellulose 1,4-beta-cellobiosidase activity - - - 0.000000000000000000000000000000000000000001871 177.0
WH2_k127_5685547_31 Uncharacterized protein conserved in bacteria (DUF2076) K09945 - - 0.0000000000000000000000000000000000000001172 157.0
WH2_k127_5685547_32 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03433 - 3.4.25.1 0.00000000001941 66.0
WH2_k127_5685547_33 exo-alpha-(2->6)-sialidase activity - - - 0.000000005823 69.0
WH2_k127_5685547_4 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 1.747e-206 647.0
WH2_k127_5685547_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 8.261e-206 659.0
WH2_k127_5685547_6 Mate efflux family protein - - - 3.34e-198 631.0
WH2_k127_5685547_7 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 569.0
WH2_k127_5685547_8 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 539.0
WH2_k127_5685547_9 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 536.0
WH2_k127_5688014_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1020.0
WH2_k127_5688014_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.121e-304 945.0
WH2_k127_5688014_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 576.0
WH2_k127_5688014_3 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 486.0
WH2_k127_5688014_4 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000003414 259.0
WH2_k127_5688014_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000001312 199.0
WH2_k127_5688014_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000006398 182.0
WH2_k127_5692377_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 4.526e-301 929.0
WH2_k127_5692377_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 3.522e-290 902.0
WH2_k127_5692377_10 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 500.0
WH2_k127_5692377_11 Glycine cleavage system T protein K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 485.0
WH2_k127_5692377_12 COG1960 Acyl-CoA dehydrogenases K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 487.0
WH2_k127_5692377_13 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 466.0
WH2_k127_5692377_14 EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 440.0
WH2_k127_5692377_15 Major facilitator superfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 437.0
WH2_k127_5692377_16 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 436.0
WH2_k127_5692377_17 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 416.0
WH2_k127_5692377_18 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 428.0
WH2_k127_5692377_19 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 416.0
WH2_k127_5692377_2 acyl-CoA dehydrogenase K09456 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 7.273e-251 784.0
WH2_k127_5692377_20 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 415.0
WH2_k127_5692377_21 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 413.0
WH2_k127_5692377_22 cytochrome c oxidase subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 400.0
WH2_k127_5692377_23 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 393.0
WH2_k127_5692377_24 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 352.0
WH2_k127_5692377_25 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 359.0
WH2_k127_5692377_26 ATP synthase A chain K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 320.0
WH2_k127_5692377_27 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 314.0
WH2_k127_5692377_28 COG3327 Phenylacetic acid-responsive transcriptional repressor K02616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003661 284.0
WH2_k127_5692377_29 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003829 256.0
WH2_k127_5692377_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 2.508e-247 773.0
WH2_k127_5692377_30 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004802 248.0
WH2_k127_5692377_31 AsnC family K03719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008025 239.0
WH2_k127_5692377_32 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
WH2_k127_5692377_33 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000001265 235.0
WH2_k127_5692377_34 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000485 228.0
WH2_k127_5692377_35 Redoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001801 228.0
WH2_k127_5692377_36 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000003794 229.0
WH2_k127_5692377_37 Domain of unknown function (DUF3471) - - - 0.00000000000000000000000000000000000000000000000000000003755 214.0
WH2_k127_5692377_38 SURF1 family K14998 GO:0006996,GO:0007005,GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0033108,GO:0033617,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000001465 207.0
WH2_k127_5692377_39 Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - - 0.0000000000000000000000000000000000000000000000000000005538 198.0
WH2_k127_5692377_4 TonB-dependent Receptor Plug Domain K16092 - - 1.144e-231 740.0
WH2_k127_5692377_40 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000002118 199.0
WH2_k127_5692377_41 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000004744 188.0
WH2_k127_5692377_42 ATP-binding protein K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000007156 190.0
WH2_k127_5692377_43 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000000000000541 157.0
WH2_k127_5692377_44 Thiol disulfide interchange protein K04084,K08344 - 1.8.1.8 0.000000000000000000000000000000000000008113 156.0
WH2_k127_5692377_45 - - - - 0.00000000000000000000000000000000000266 154.0
WH2_k127_5692377_46 FR47-like protein - - - 0.00000000000000000000000000000000003095 141.0
WH2_k127_5692377_47 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000003053 125.0
WH2_k127_5692377_48 Plant ATP synthase F0 K02109 - - 0.0000000000000000000000000000148 123.0
WH2_k127_5692377_49 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000002261 113.0
WH2_k127_5692377_5 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 3.065e-227 713.0
WH2_k127_5692377_50 - - - - 0.000000000000000000000000003386 117.0
WH2_k127_5692377_51 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000001874 111.0
WH2_k127_5692377_52 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000000000000075 84.0
WH2_k127_5692377_53 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.000000000000001066 78.0
WH2_k127_5692377_54 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000000000003941 78.0
WH2_k127_5692377_55 RESPONSE REGULATOR receiver - - - 0.00000000001822 70.0
WH2_k127_5692377_56 - - - - 0.00000004069 65.0
WH2_k127_5692377_57 - - - - 0.00000008862 59.0
WH2_k127_5692377_6 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 602.0
WH2_k127_5692377_7 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 596.0
WH2_k127_5692377_8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 595.0
WH2_k127_5692377_9 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 553.0
WH2_k127_570290_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 2.168e-250 791.0
WH2_k127_570290_1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 588.0
WH2_k127_570290_2 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 462.0
WH2_k127_570290_3 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000003564 128.0
WH2_k127_570290_4 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00004266 50.0
WH2_k127_5717300_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid K00130 - 1.2.1.8 5.032e-200 631.0
WH2_k127_5717300_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 6.554e-194 614.0
WH2_k127_5717300_2 COG0076 Glutamate decarboxylase and related PLP-dependent proteins K01634 - 4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 327.0
WH2_k127_5717300_3 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000009743 173.0
WH2_k127_5732868_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1124.0
WH2_k127_5732868_1 This protein is involved in the repair of mismatches in DNA K03555 - - 3.817e-197 626.0
WH2_k127_5732868_10 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000276 247.0
WH2_k127_5732868_11 Phosphomethylpyrimidine kinase K00868 - 2.7.1.35 0.0000000000000000000000000000000000000000000000000000000000002656 221.0
WH2_k127_5732868_12 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000772 196.0
WH2_k127_5732868_13 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000000000006722 172.0
WH2_k127_5732868_14 2 iron, 2 sulfur cluster binding - - - 0.00000000000000000000000000000000000000004367 165.0
WH2_k127_5732868_15 Belongs to the UPF0145 family - - - 0.000000000000000000000000000004026 126.0
WH2_k127_5732868_16 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000002829 117.0
WH2_k127_5732868_17 Cupredoxin-like domain - - - 0.000000000000000000000002822 106.0
WH2_k127_5732868_18 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000002152 90.0
WH2_k127_5732868_19 Transglutaminase-like superfamily - - - 0.00000000000004248 79.0
WH2_k127_5732868_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 551.0
WH2_k127_5732868_21 SnoaL-like domain - - - 0.00001217 53.0
WH2_k127_5732868_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 390.0
WH2_k127_5732868_4 radical SAM domain protein K21551 - 2.1.1.106 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 389.0
WH2_k127_5732868_5 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 397.0
WH2_k127_5732868_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 353.0
WH2_k127_5732868_7 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001136 271.0
WH2_k127_5732868_8 transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001116 281.0
WH2_k127_5732868_9 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001859 259.0
WH2_k127_5736549_0 Chain length determinant protein K16554 - - 6.687e-257 814.0
WH2_k127_5736549_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 1.314e-214 676.0
WH2_k127_5736549_10 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 449.0
WH2_k127_5736549_11 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 442.0
WH2_k127_5736549_12 transferase activity, transferring glycosyl groups K16558 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 445.0
WH2_k127_5736549_13 TRAP-type C4-dicarboxylate transport system periplasmic component K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 406.0
WH2_k127_5736549_14 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377,K16554 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 398.0
WH2_k127_5736549_15 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 406.0
WH2_k127_5736549_16 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 390.0
WH2_k127_5736549_17 Histidine kinase-like ATPases K14980 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 387.0
WH2_k127_5736549_18 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 374.0
WH2_k127_5736549_19 Transcriptional regulator K13641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 372.0
WH2_k127_5736549_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 2.225e-200 634.0
WH2_k127_5736549_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 371.0
WH2_k127_5736549_21 Uncharacterized protein conserved in bacteria (DUF2325) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 376.0
WH2_k127_5736549_22 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 370.0
WH2_k127_5736549_23 enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 349.0
WH2_k127_5736549_24 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 331.0
WH2_k127_5736549_25 TRAP-type C4-dicarboxylate transport system, large permease component K21393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 319.0
WH2_k127_5736549_26 Putative beta-barrel porin 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 308.0
WH2_k127_5736549_27 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K21393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 289.0
WH2_k127_5736549_28 enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 287.0
WH2_k127_5736549_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000362 269.0
WH2_k127_5736549_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 600.0
WH2_k127_5736549_30 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000006751 279.0
WH2_k127_5736549_31 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003166 242.0
WH2_k127_5736549_32 Transcriptional regulator, TetR, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000001656 236.0
WH2_k127_5736549_33 Tripartite ATP-independent periplasmic transporter dctq component K21394 - - 0.000000000000000000000000000000000000000000000000000000003246 205.0
WH2_k127_5736549_34 COG1596 Periplasmic protein involved in polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000000000001013 199.0
WH2_k127_5736549_35 TOBE domain - - - 0.000000000000000000000000000103 116.0
WH2_k127_5736549_36 ABC transporter K01995 - - 0.000000000000000000000000008187 109.0
WH2_k127_5736549_37 Periplasmic copper-binding protein (NosD) - - - 0.0002074 54.0
WH2_k127_5736549_4 COG2148 Sugar transferases involved in lipopolysaccharide synthesis K03606,K20997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 545.0
WH2_k127_5736549_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 514.0
WH2_k127_5736549_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 485.0
WH2_k127_5736549_7 Glycosyl transferase 4-like domain K03208 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 477.0
WH2_k127_5736549_8 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 461.0
WH2_k127_5736549_9 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 465.0
WH2_k127_5744434_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 6.775e-223 710.0
WH2_k127_5744434_1 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 597.0
WH2_k127_5744434_10 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 378.0
WH2_k127_5744434_11 Cell wall formation K00075,K01921 - 1.3.1.98,6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 376.0
WH2_k127_5744434_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 351.0
WH2_k127_5744434_13 Cell division protein FtsQ K03589 - - 0.0000000000000000000000000000000000000000425 169.0
WH2_k127_5744434_14 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000007722 113.0
WH2_k127_5744434_15 Bacterial protein of unknown function (DUF883) - - - 0.00000000002195 70.0
WH2_k127_5744434_16 secreted (Periplasmic) protein - - - 0.000000007812 67.0
WH2_k127_5744434_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 542.0
WH2_k127_5744434_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 505.0
WH2_k127_5744434_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 503.0
WH2_k127_5744434_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 495.0
WH2_k127_5744434_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 457.0
WH2_k127_5744434_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 436.0
WH2_k127_5744434_8 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 427.0
WH2_k127_5744434_9 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 399.0
WH2_k127_5766183_0 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000007617 147.0
WH2_k127_5766183_1 dNA-binding protein - - - 0.000000000000000000000000000000002942 135.0
WH2_k127_5766183_2 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000002633 136.0
WH2_k127_5766183_3 - - - - 0.000000000000000000000000001461 116.0
WH2_k127_5766183_4 Helix-turn-helix domain - - - 0.000000000000000236 83.0
WH2_k127_5766183_6 transcriptional - - - 0.0000004006 56.0
WH2_k127_5766183_8 Helix-turn-helix - - - 0.0001627 48.0
WH2_k127_5766183_9 Peptidase S24-like K01356 - 3.4.21.88 0.0008796 48.0
WH2_k127_5766413_0 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 489.0
WH2_k127_5766413_1 signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 364.0
WH2_k127_5766413_2 SprA-related family - - - 0.000000000000000000000000000000009574 136.0
WH2_k127_5766413_3 transport system permease component K02037 - - 0.0000000008955 64.0
WH2_k127_5769406_0 transport system, fused permease components - - - 2.594e-247 798.0
WH2_k127_5769406_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 477.0
WH2_k127_5769406_2 TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 432.0
WH2_k127_5769406_3 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 368.0
WH2_k127_5769406_4 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000007491 253.0
WH2_k127_5769406_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000001387 210.0
WH2_k127_5769406_6 MltA-interacting MipA family protein - - - 0.000000000000000000000000000000000000000000000002022 184.0
WH2_k127_5769406_7 Domain of unknown function (DUF1850) - - - 0.000000000000000000000000009265 128.0
WH2_k127_5769406_8 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0000000000000001438 86.0
WH2_k127_5777906_0 ABC transporter K06147,K11004 - - 2.174e-273 858.0
WH2_k127_5777906_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 372.0
WH2_k127_5777906_2 TIGRFAM type I secretion membrane fusion protein, HlyD family K11003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 360.0
WH2_k127_5777906_3 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002744 278.0
WH2_k127_5826684_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 546.0
WH2_k127_5826684_1 COG1609 Transcriptional regulators K06145 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 399.0
WH2_k127_5826684_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 340.0
WH2_k127_5826684_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002933 262.0
WH2_k127_5826684_4 Transcriptional regulator K19591 - - 0.000000000000000000000000000000000000000000000000000004849 193.0
WH2_k127_5826684_5 Shikimate kinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000001244 193.0
WH2_k127_5826684_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000001722 123.0
WH2_k127_5826684_7 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000228 50.0
WH2_k127_5827020_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 583.0
WH2_k127_5827020_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 477.0
WH2_k127_5827020_10 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000003834 124.0
WH2_k127_5827020_11 gamma-glutamylcyclotransferase activity - - - 0.00000000000000005507 94.0
WH2_k127_5827020_12 - - - - 0.0000000005318 65.0
WH2_k127_5827020_2 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 390.0
WH2_k127_5827020_3 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 364.0
WH2_k127_5827020_4 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004858 302.0
WH2_k127_5827020_5 LysR substrate binding domain K18297 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001892 269.0
WH2_k127_5827020_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000004041 198.0
WH2_k127_5827020_7 - - - - 0.000000000000000000000000000000000000000000000002642 183.0
WH2_k127_5827020_8 Dopa 4,5-dioxygenase family K10253 - - 0.0000000000000000000000000000000000000000000002344 172.0
WH2_k127_5827020_9 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000002993 127.0
WH2_k127_5842349_0 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 496.0
WH2_k127_5842349_1 NeuB family K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 427.0
WH2_k127_5842349_10 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000009126 137.0
WH2_k127_5842349_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06602 - - 0.00000000000000000000000000007225 120.0
WH2_k127_5842349_12 Transposase, Mutator family K07493 - - 0.00000000000000006401 85.0
WH2_k127_5842349_13 transposase activity - - - 0.0000000000000001005 82.0
WH2_k127_5842349_14 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000547 75.0
WH2_k127_5842349_2 Dihydrodipicolinate synthase N-acetylneuraminate lyase K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 393.0
WH2_k127_5842349_3 Transposase, Mutator family K07493 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 325.0
WH2_k127_5842349_4 Transcriptional regulator K13641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 294.0
WH2_k127_5842349_5 Protein of unknown function DUF115 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009585 289.0
WH2_k127_5842349_6 Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000005515 200.0
WH2_k127_5842349_7 Transposase, Mutator family K07493 - - 0.0000000000000000000000000000000000000000000000000004086 191.0
WH2_k127_5842349_8 Protein of unknown function DUF115 - - - 0.0000000000000000000000000000000000000000000000002141 198.0
WH2_k127_5842349_9 Flagellar protein FlbT K06601 - - 0.000000000000000000000000000002161 124.0
WH2_k127_5867913_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.482e-274 857.0
WH2_k127_5867913_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.41e-238 743.0
WH2_k127_5867913_10 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 291.0
WH2_k127_5867913_11 Cytidylate kinase K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000001343 251.0
WH2_k127_5867913_12 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000000000001875 231.0
WH2_k127_5867913_13 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000008879 200.0
WH2_k127_5867913_14 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000002937 198.0
WH2_k127_5867913_15 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000005006 195.0
WH2_k127_5867913_16 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000002473 193.0
WH2_k127_5867913_17 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000002628 171.0
WH2_k127_5867913_18 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000009093 172.0
WH2_k127_5867913_19 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000007643 171.0
WH2_k127_5867913_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.155e-199 632.0
WH2_k127_5867913_20 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000007687 154.0
WH2_k127_5867913_21 Putative zinc-finger - - - 0.0000000000000000000000000000000000000007964 152.0
WH2_k127_5867913_22 NUDIX domain - - - 0.00000000000000000000000000000001674 138.0
WH2_k127_5867913_23 HEAT repeats - - - 0.00000000000000000000000000000003259 133.0
WH2_k127_5867913_24 Transglutaminase-like superfamily - - - 0.000000000000000000000000000003326 125.0
WH2_k127_5867913_25 NUDIX hydrolase - - - 0.000000000000000000000000000004121 130.0
WH2_k127_5867913_26 Protein of unknown function (FYDLN_acid) - - - 0.0000000000000000000005335 99.0
WH2_k127_5867913_27 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000203 82.0
WH2_k127_5867913_3 chemotaxis K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 513.0
WH2_k127_5867913_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 466.0
WH2_k127_5867913_5 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 452.0
WH2_k127_5867913_6 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 397.0
WH2_k127_5867913_7 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 374.0
WH2_k127_5867913_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 359.0
WH2_k127_5867913_9 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 312.0
WH2_k127_5881926_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 1.117e-216 700.0
WH2_k127_5881926_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 391.0
WH2_k127_5881926_2 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 373.0
WH2_k127_5881926_3 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000009092 263.0
WH2_k127_5881926_4 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000212 194.0
WH2_k127_5891438_0 DNA helicase K03657 - 3.6.4.12 4.166e-298 932.0
WH2_k127_5891438_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.308e-245 781.0
WH2_k127_5891438_10 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 450.0
WH2_k127_5891438_11 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 443.0
WH2_k127_5891438_12 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 413.0
WH2_k127_5891438_13 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 411.0
WH2_k127_5891438_14 Binding-protein-dependent transport system inner membrane component K02029,K10002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 377.0
WH2_k127_5891438_15 FCD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 373.0
WH2_k127_5891438_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 358.0
WH2_k127_5891438_17 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 358.0
WH2_k127_5891438_18 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 361.0
WH2_k127_5891438_19 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 300.0
WH2_k127_5891438_2 aminopeptidase K01262 - 3.4.11.9 5.924e-245 773.0
WH2_k127_5891438_20 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 292.0
WH2_k127_5891438_21 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003561 280.0
WH2_k127_5891438_22 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003317 291.0
WH2_k127_5891438_23 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001753 254.0
WH2_k127_5891438_24 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000344 227.0
WH2_k127_5891438_25 Protein of unknown function (DUF3830) - - - 0.000000000000000000000000000000000000000000000000000000000000004942 218.0
WH2_k127_5891438_26 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000000004235 216.0
WH2_k127_5891438_27 COG0314 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000007375 215.0
WH2_k127_5891438_28 ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000003707 216.0
WH2_k127_5891438_29 AMP-binding enzyme C-terminal domain K15868 - 6.2.1.7 0.000000000000000000000000000000000000000000000003883 181.0
WH2_k127_5891438_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.198e-241 764.0
WH2_k127_5891438_31 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000000000007321 117.0
WH2_k127_5891438_32 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000346 110.0
WH2_k127_5891438_33 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000001793 104.0
WH2_k127_5891438_34 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000001949 100.0
WH2_k127_5891438_35 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00003313 52.0
WH2_k127_5891438_4 Permeases of the major facilitator superfamily - - - 1.469e-194 615.0
WH2_k127_5891438_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 638.0
WH2_k127_5891438_6 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 546.0
WH2_k127_5891438_7 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 535.0
WH2_k127_5891438_8 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 473.0
WH2_k127_5891438_9 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 468.0
WH2_k127_5914003_0 Type IV secretory system Conjugative DNA transfer K03205 - - 0.0 1295.0
WH2_k127_5914003_1 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03497 - - 0.0 1139.0
WH2_k127_5914003_10 Protein of unknown function (DUF2493) - - - 1.859e-194 608.0
WH2_k127_5914003_11 Alanine-glyoxylate amino-transferase - - - 2.879e-194 614.0
WH2_k127_5914003_12 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 582.0
WH2_k127_5914003_13 TRAP-type C4-dicarboxylate transport system periplasmic component K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 550.0
WH2_k127_5914003_14 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 548.0
WH2_k127_5914003_15 unfolded protein binding K04079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 534.0
WH2_k127_5914003_16 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 481.0
WH2_k127_5914003_17 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 458.0
WH2_k127_5914003_18 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 395.0
WH2_k127_5914003_19 LysR substrate binding domain K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 398.0
WH2_k127_5914003_2 Protein of unknown function (DUF3363) - - - 0.0 1093.0
WH2_k127_5914003_20 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 411.0
WH2_k127_5914003_21 lytic transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 377.0
WH2_k127_5914003_22 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 370.0
WH2_k127_5914003_23 Protein conserved in bacteria K09990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 364.0
WH2_k127_5914003_24 Signal peptidase, peptidase S26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 366.0
WH2_k127_5914003_25 Protein of unknown function (DUF2840) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 332.0
WH2_k127_5914003_26 unfolded protein binding K04079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 344.0
WH2_k127_5914003_28 PFAM 6-phosphogluconate dehydrogenase NAD-binding K08319 - 1.1.1.411 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 339.0
WH2_k127_5914003_29 chromosome segregation K12055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002191 281.0
WH2_k127_5914003_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 1.455e-308 957.0
WH2_k127_5914003_30 copG family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001557 253.0
WH2_k127_5914003_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000294 248.0
WH2_k127_5914003_32 Uncharacterized conserved protein (DUF2285) - - - 0.000000000000000000000000000000000000000000000000000000000000000007717 231.0
WH2_k127_5914003_33 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000009166 228.0
WH2_k127_5914003_34 Protein of unknown function (DUF736) - - - 0.000000000000000000000000000000000000000000000000000000000000002394 219.0
WH2_k127_5914003_35 Protein of unknown function (DUF736) - - - 0.000000000000000000000000000000000000000000000000000000000001439 220.0
WH2_k127_5914003_36 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000002728 203.0
WH2_k127_5914003_37 Helix-turn-helix K07726 - - 0.00000000000000000000000000000000000000000000000000000002026 198.0
WH2_k127_5914003_38 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000002043 185.0
WH2_k127_5914003_39 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.000000000000000000000000000000000000000000000002898 176.0
WH2_k127_5914003_4 radical SAM domain protein - - - 2.928e-284 880.0
WH2_k127_5914003_40 Uncharacterized conserved protein (DUF2285) - - - 0.000000000000000000000000000000000000001441 148.0
WH2_k127_5914003_41 - - - - 0.000000000000000000000000000000000000001972 154.0
WH2_k127_5914003_43 - - - - 0.00000000000000000000000002671 109.0
WH2_k127_5914003_44 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000009126 108.0
WH2_k127_5914003_46 - - - - 0.0000000000000000000004606 97.0
WH2_k127_5914003_47 - - - - 0.000000000000000001466 95.0
WH2_k127_5914003_48 DNA-sulfur modification-associated - - - 0.0000000000000002216 91.0
WH2_k127_5914003_49 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.000000000003081 69.0
WH2_k127_5914003_5 - - - - 4.101e-249 771.0
WH2_k127_5914003_6 Replication initiator protein A - - - 3.778e-222 693.0
WH2_k127_5914003_7 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 1.73e-220 710.0
WH2_k127_5914003_8 Thiamine pyrophosphate enzyme, central domain K00156,K00158 - 1.2.3.3,1.2.5.1 3.696e-219 697.0
WH2_k127_5914003_9 Toprim domain - - - 4.611e-207 646.0
WH2_k127_5924502_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.06e-248 774.0
WH2_k127_5924502_1 Amino acid permease - - - 4.955e-204 658.0
WH2_k127_5924502_10 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 383.0
WH2_k127_5924502_11 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 387.0
WH2_k127_5924502_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 379.0
WH2_k127_5924502_13 ATPases associated with a variety of cellular activities K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 332.0
WH2_k127_5924502_14 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 317.0
WH2_k127_5924502_15 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 323.0
WH2_k127_5924502_16 ABC transporter K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 305.0
WH2_k127_5924502_17 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002139 252.0
WH2_k127_5924502_18 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000003383 233.0
WH2_k127_5924502_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000004499 225.0
WH2_k127_5924502_2 Carboxymethylenebutenolidase K01061 - 3.1.1.45 2.774e-203 640.0
WH2_k127_5924502_20 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000008016 218.0
WH2_k127_5924502_21 Domain of unknown function (DUF4865) - - - 0.00000000000000000000000000000000000000000000000000000002184 207.0
WH2_k127_5924502_22 Tautomerase enzyme - - - 0.000000000000000000000000000000000000000000000000007211 184.0
WH2_k127_5924502_23 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000004129 137.0
WH2_k127_5924502_24 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000005817 131.0
WH2_k127_5924502_25 - - - - 0.00000000000000000000000005904 122.0
WH2_k127_5924502_26 phosphorelay signal transduction system - - - 0.0000000000002207 79.0
WH2_k127_5924502_27 ABC transporter C-terminal domain K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 0.00000000001052 66.0
WH2_k127_5924502_28 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.000000001461 68.0
WH2_k127_5924502_3 Aromatic amino acid lyase K01745 - 4.3.1.3 2.937e-195 620.0
WH2_k127_5924502_4 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 456.0
WH2_k127_5924502_5 ATPases associated with a variety of cellular activities K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 422.0
WH2_k127_5924502_6 response to pH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 425.0
WH2_k127_5924502_7 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 404.0
WH2_k127_5924502_8 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 394.0
WH2_k127_5924502_9 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 381.0
WH2_k127_5962897_0 Dehydratase family K22186 - 4.2.1.82 0.0 1003.0
WH2_k127_5962897_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - 3.556e-278 871.0
WH2_k127_5962897_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 501.0
WH2_k127_5962897_11 epimerase dehydratase K22025 - 1.1.1.410 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 487.0
WH2_k127_5962897_12 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 476.0
WH2_k127_5962897_13 ABC-type sugar transport systems permease components K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 462.0
WH2_k127_5962897_14 maleylacetate reductase K00217 - 1.3.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 462.0
WH2_k127_5962897_15 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 421.0
WH2_k127_5962897_16 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 395.0
WH2_k127_5962897_17 Catechol dioxygenase N terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 398.0
WH2_k127_5962897_18 amino acid transport K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 418.0
WH2_k127_5962897_19 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 385.0
WH2_k127_5962897_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.123e-270 842.0
WH2_k127_5962897_20 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 378.0
WH2_k127_5962897_21 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 370.0
WH2_k127_5962897_22 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 384.0
WH2_k127_5962897_23 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 343.0
WH2_k127_5962897_24 Carbon monoxide dehydrogenase operon C protein K21696 GO:0006355,GO:0006808,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 341.0
WH2_k127_5962897_25 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 333.0
WH2_k127_5962897_26 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 333.0
WH2_k127_5962897_27 Aldo/keto reductase family K06222 - 1.1.1.346 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 326.0
WH2_k127_5962897_28 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K18335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 323.0
WH2_k127_5962897_29 COG0410 ABC-type branched-chain amino acid transport systems ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 298.0
WH2_k127_5962897_3 belongs to the aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 1.327e-258 803.0
WH2_k127_5962897_30 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 303.0
WH2_k127_5962897_31 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003485 276.0
WH2_k127_5962897_32 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000229 260.0
WH2_k127_5962897_33 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000001047 261.0
WH2_k127_5962897_34 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004418 230.0
WH2_k127_5962897_35 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000004932 201.0
WH2_k127_5962897_36 Belongs to the UPF0311 family - - - 0.0000000000000000000000000000000000000000000006957 170.0
WH2_k127_5962897_37 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000002171 159.0
WH2_k127_5962897_38 - - - - 0.000000000000000000003181 99.0
WH2_k127_5962897_4 D-galactarate dehydratase Altronate hydrolase K01685 - 4.2.1.7 1.395e-246 770.0
WH2_k127_5962897_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 5.864e-225 703.0
WH2_k127_5962897_6 Fumarylacetoacetate (FAA) hydrolase family - - - 5.376e-201 631.0
WH2_k127_5962897_7 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 598.0
WH2_k127_5962897_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 582.0
WH2_k127_5962897_9 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 518.0
WH2_k127_5994898_0 Transglutaminase/protease-like homologues - - - 0.0 1495.0
WH2_k127_5994898_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 293.0
WH2_k127_5994898_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000004838 212.0
WH2_k127_5994898_3 Circularly permuted ATP-grasp type 2 - - - 0.0000000000000000000000000000000000000000000000001854 187.0
WH2_k127_6035930_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 512.0
WH2_k127_6035930_1 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000003087 138.0
WH2_k127_6035930_2 FCD - - - 0.000000000000000000000000000000009863 131.0
WH2_k127_6037367_0 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates K01637 - 4.1.3.1 6.854e-312 960.0
WH2_k127_6037367_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 7.72e-249 781.0
WH2_k127_6037367_10 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 391.0
WH2_k127_6037367_11 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 314.0
WH2_k127_6037367_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002895 246.0
WH2_k127_6037367_13 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000002249 138.0
WH2_k127_6037367_14 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000001045 123.0
WH2_k127_6037367_16 Antitoxin component of bacterial toxin-antitoxin system, MqsA K13655 - - 0.000000000235 75.0
WH2_k127_6037367_17 - - - - 0.0000001626 53.0
WH2_k127_6037367_18 oxidoreductase K06940 - - 0.0000001694 56.0
WH2_k127_6037367_19 - - - - 0.0000001938 63.0
WH2_k127_6037367_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 1.638e-207 656.0
WH2_k127_6037367_21 - - - - 0.0000002753 52.0
WH2_k127_6037367_23 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000006674 55.0
WH2_k127_6037367_24 Integrase core domain K07497 - - 0.0006291 42.0
WH2_k127_6037367_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 608.0
WH2_k127_6037367_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 568.0
WH2_k127_6037367_5 transcriptional regulator K07110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 563.0
WH2_k127_6037367_6 RNA polymerase sigma K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 456.0
WH2_k127_6037367_7 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 402.0
WH2_k127_6037367_8 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 393.0
WH2_k127_6037367_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 422.0
WH2_k127_6038718_0 TonB-dependent receptor K16090 - - 7.703e-228 725.0
WH2_k127_6038718_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 564.0
WH2_k127_6038718_2 2OG-Fe(II) oxygenase K07336 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 326.0
WH2_k127_6038718_3 Belongs to the GcvT family K00302 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003475 263.0
WH2_k127_6038718_4 Sarcosine oxidase delta subunit K00304 - 1.5.3.1 0.00000000000000000000000000000000003547 137.0
WH2_k127_6102489_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1351.0
WH2_k127_6102489_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.198e-237 763.0
WH2_k127_6102489_10 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000005498 230.0
WH2_k127_6102489_11 COG2030 Acyl dehydratase K17865 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016043,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0042620,GO:0042621,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901576 4.2.1.55 0.0000000000000000000000000000000000000000000000000001563 189.0
WH2_k127_6102489_12 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000001367 156.0
WH2_k127_6102489_13 Protein of unknown function (DUF3035) - - - 0.0000000000000000000000000000000000000001691 159.0
WH2_k127_6102489_14 Gram-negative porin K08720 - - 0.000000000000000000000000000000000000001168 167.0
WH2_k127_6102489_15 chemotaxis protein K03414 - - 0.000000000000000000000000000000000000002682 155.0
WH2_k127_6102489_16 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000004534 150.0
WH2_k127_6102489_17 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000001411 141.0
WH2_k127_6102489_18 transcriptional regulator - - - 0.00000000000000000000000000000009838 131.0
WH2_k127_6102489_2 sensor histidine kinase with multiple PAS PAC and a response regulator receiver domain K19694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 547.0
WH2_k127_6102489_3 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 525.0
WH2_k127_6102489_4 oxidase, subunit K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 437.0
WH2_k127_6102489_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009512 371.0
WH2_k127_6102489_6 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 352.0
WH2_k127_6102489_7 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 338.0
WH2_k127_6102489_8 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 310.0
WH2_k127_6102489_9 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000221 252.0
WH2_k127_6103434_0 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 7.15e-207 654.0
WH2_k127_6103434_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 561.0
WH2_k127_6103434_10 COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000003849 230.0
WH2_k127_6103434_11 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001196 194.0
WH2_k127_6103434_12 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000005509 192.0
WH2_k127_6103434_13 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000001451 200.0
WH2_k127_6103434_14 MarR family - - - 0.0000000000000000000000000000000000000000000135 167.0
WH2_k127_6103434_15 - - - - 0.00000000000000000000000000000000000005326 150.0
WH2_k127_6103434_16 Domain of unknown function (DUF1987) - - - 0.000000000000000000000000000000001709 133.0
WH2_k127_6103434_17 Acylphosphatase - - - 0.00000000000000000003491 98.0
WH2_k127_6103434_2 Belongs to the peptidase S1C family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 530.0
WH2_k127_6103434_3 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 480.0
WH2_k127_6103434_4 AraC family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 430.0
WH2_k127_6103434_5 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 381.0
WH2_k127_6103434_6 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 362.0
WH2_k127_6103434_7 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 286.0
WH2_k127_6103434_8 AsmA family K07289,K07290 - - 0.000000000000000000000000000000000000000000000000000000000000000000001056 266.0
WH2_k127_6103434_9 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000008277 239.0
WH2_k127_616503_0 Phosphopantetheine attachment site - - - 0.0 1454.0
WH2_k127_616503_1 Aldehyde dehydrogenase family K00128,K09472 - 1.2.1.3,1.2.1.99 7.214e-221 696.0
WH2_k127_616503_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 499.0
WH2_k127_616503_3 Taurine catabolism dioxygenase TauD TfdA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 394.0
WH2_k127_616503_4 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 357.0
WH2_k127_616503_5 thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003313 277.0
WH2_k127_616503_6 Fe2 -dicitrate sensor, membrane component K07165 - - 0.0000000000000000000000000000000000000000000000000000000000000000005683 241.0
WH2_k127_616503_7 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000001749 188.0
WH2_k127_616503_8 PFAM MbtH domain protein K05375 - - 0.000000000000000000000000006288 111.0
WH2_k127_61676_0 AcrB/AcrD/AcrF family - - - 0.0 1823.0
WH2_k127_61676_1 NADH:flavin oxidoreductase / NADH oxidase family K09461 - 1.14.13.40 2.069e-305 956.0
WH2_k127_61676_10 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 412.0
WH2_k127_61676_11 Binding-protein-dependent transport system inner membrane component K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 410.0
WH2_k127_61676_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 382.0
WH2_k127_61676_13 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 368.0
WH2_k127_61676_14 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 310.0
WH2_k127_61676_15 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 302.0
WH2_k127_61676_16 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 302.0
WH2_k127_61676_17 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 281.0
WH2_k127_61676_18 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003294 284.0
WH2_k127_61676_19 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001703 269.0
WH2_k127_61676_2 ABC-type sugar transport system periplasmic component K02027,K05813 - - 3.552e-210 660.0
WH2_k127_61676_20 Phytanoyl-CoA dioxygenase (PhyH) K00477 - 1.14.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000006015 271.0
WH2_k127_61676_21 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000785 265.0
WH2_k127_61676_22 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000016 244.0
WH2_k127_61676_23 RES - - - 0.000000000000000000000000000000000000000000000000000000000000000000471 234.0
WH2_k127_61676_24 Protein of unknown function (DUF2384) - - - 0.000000000000000000000000000000000000000000000000000000000000000007236 227.0
WH2_k127_61676_25 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000001348 162.0
WH2_k127_61676_26 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000001094 123.0
WH2_k127_61676_27 DNA-binding transcription factor activity - - - 0.0000000000000000000000009989 118.0
WH2_k127_61676_3 Amp-dependent synthetase and ligase K08295 - 6.2.1.32 4.095e-207 657.0
WH2_k127_61676_4 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 531.0
WH2_k127_61676_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 494.0
WH2_k127_61676_6 COG3839 ABC-type sugar transport systems, ATPase components K05816 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 447.0
WH2_k127_61676_7 Carbon-nitrogen hydrolase K01502 - 3.5.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 442.0
WH2_k127_61676_8 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 435.0
WH2_k127_61676_9 ABC-type sugar transport systems permease components K02025,K05814,K10118,K17242,K17245 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 426.0
WH2_k127_617040_0 Amino acid adenylation domain - - - 0.0 1242.0
WH2_k127_617040_1 amino acid adenylation domain protein K02364 - 6.3.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 447.0
WH2_k127_61870_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2153.0
WH2_k127_61870_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 3.957e-306 944.0
WH2_k127_61870_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 346.0
WH2_k127_61870_3 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 287.0
WH2_k127_61870_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000001286 223.0
WH2_k127_61870_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000009723 213.0
WH2_k127_61870_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000001223 188.0
WH2_k127_61870_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001941 78.0
WH2_k127_61870_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000002907 82.0
WH2_k127_61870_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00002182 49.0
WH2_k127_6210716_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1261.0
WH2_k127_6210716_1 Putative diguanylate phosphodiesterase - - - 0.0 1135.0
WH2_k127_6210716_10 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001292 261.0
WH2_k127_6210716_11 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000001985 247.0
WH2_k127_6210716_12 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000108 191.0
WH2_k127_6210716_13 COG3658 Cytochrome b - - - 0.000000000000000000000000000000000000000000001972 173.0
WH2_k127_6210716_14 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000006267 169.0
WH2_k127_6210716_15 Acetyltransferase K03829 - - 0.00000000000000000000000000000000000000494 151.0
WH2_k127_6210716_16 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.00000000000000000000000000000000000006129 148.0
WH2_k127_6210716_17 5-aminolevulinic acid synthase K00652 - 2.3.1.47 0.00000000000000000000000000000000009778 138.0
WH2_k127_6210716_18 Cytochrome C' - - - 0.0000000000000000000000007026 109.0
WH2_k127_6210716_2 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 6.924e-225 700.0
WH2_k127_6210716_3 ATP dependent DNA ligase C terminal region K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.222e-213 689.0
WH2_k127_6210716_4 Psort location Cytoplasmic, score 7.50 - - - 1.419e-210 670.0
WH2_k127_6210716_5 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 576.0
WH2_k127_6210716_6 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 488.0
WH2_k127_6210716_7 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 489.0
WH2_k127_6210716_8 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 365.0
WH2_k127_6210716_9 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 303.0
WH2_k127_6227309_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1111.0
WH2_k127_6227309_1 ABC transporter transmembrane region K02021 - - 1.631e-278 884.0
WH2_k127_6227309_10 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 518.0
WH2_k127_6227309_11 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 480.0
WH2_k127_6227309_12 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 481.0
WH2_k127_6227309_13 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 465.0
WH2_k127_6227309_14 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 421.0
WH2_k127_6227309_15 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 417.0
WH2_k127_6227309_16 pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 404.0
WH2_k127_6227309_17 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 383.0
WH2_k127_6227309_18 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 361.0
WH2_k127_6227309_19 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 349.0
WH2_k127_6227309_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 5.987e-253 789.0
WH2_k127_6227309_20 COG0708 Exonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 343.0
WH2_k127_6227309_21 Ring hydroxylating alpha subunit (catalytic domain) K00479,K16319 - 1.14.12.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 330.0
WH2_k127_6227309_22 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 329.0
WH2_k127_6227309_23 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 327.0
WH2_k127_6227309_24 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 324.0
WH2_k127_6227309_25 Steryl acetyl hydrolase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 309.0
WH2_k127_6227309_26 PFAM D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 327.0
WH2_k127_6227309_27 KR domain K00059,K07535 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001132 278.0
WH2_k127_6227309_28 PFAM Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000001414 254.0
WH2_k127_6227309_29 Ring hydroxylating beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000005132 223.0
WH2_k127_6227309_3 AMP-binding enzyme K01897 - 6.2.1.3 1.037e-239 756.0
WH2_k127_6227309_30 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000001658 237.0
WH2_k127_6227309_31 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000455 192.0
WH2_k127_6227309_32 S-adenosyl-L-methionine methyltransferase - - - 0.00000000000000000000000000000000000000000000000003712 191.0
WH2_k127_6227309_33 Enoyl-CoA hydratase/isomerase K01692,K15866 - 4.2.1.17,5.3.3.18 0.000000000000000000000000000000000000000000002179 174.0
WH2_k127_6227309_34 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000002032 152.0
WH2_k127_6227309_35 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000003388 142.0
WH2_k127_6227309_36 flavin adenine dinucleotide binding - - - 0.000000000000000000000000000000000108 141.0
WH2_k127_6227309_37 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000006914 133.0
WH2_k127_6227309_38 Acetyltransferase (GNAT) family - - - 0.000000000000000000002081 109.0
WH2_k127_6227309_39 - - - - 0.00000000000000000001847 100.0
WH2_k127_6227309_4 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 6.621e-224 706.0
WH2_k127_6227309_40 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.00000000000000123 88.0
WH2_k127_6227309_5 Thiolase, N-terminal domain K00626 - 2.3.1.9 6.892e-200 630.0
WH2_k127_6227309_6 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 541.0
WH2_k127_6227309_7 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 544.0
WH2_k127_6227309_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 517.0
WH2_k127_6227309_9 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 526.0
WH2_k127_6384776_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.075e-229 722.0
WH2_k127_6384776_1 FAD dependent oxidoreductase K00303,K22084 - 1.5.3.1,1.5.99.5 1.213e-227 716.0
WH2_k127_6384776_10 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 385.0
WH2_k127_6384776_11 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 338.0
WH2_k127_6384776_12 Thioesterase superfamily - - - 0.0000000000000000000000000000000000001016 147.0
WH2_k127_6384776_13 Sarcosine oxidase, delta subunit family K22085 - 1.5.99.5 0.00000000000000000000000000007505 119.0
WH2_k127_6384776_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 602.0
WH2_k127_6384776_3 Periplasmic binding proteins and sugar binding domain of LacI family K02058,K10439,K17213 GO:0003674,GO:0005215,GO:0005488,GO:0005534,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015749,GO:0015757,GO:0016020,GO:0016021,GO:0022857,GO:0030246,GO:0030288,GO:0030313,GO:0031224,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0044425,GO:0044464,GO:0048029,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 565.0
WH2_k127_6384776_4 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 542.0
WH2_k127_6384776_5 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 541.0
WH2_k127_6384776_6 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 508.0
WH2_k127_6384776_7 Belongs to the GcvT family K00302,K22086 - 1.5.3.1,1.5.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 489.0
WH2_k127_6384776_8 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 487.0
WH2_k127_6384776_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 394.0
WH2_k127_6431447_0 Homospermidine synthase K00808 - 2.5.1.44 2.236e-242 754.0
WH2_k127_6431447_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 559.0
WH2_k127_6431447_2 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 421.0
WH2_k127_6431447_3 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 312.0
WH2_k127_6431447_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 305.0
WH2_k127_6431447_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003333 250.0
WH2_k127_6431447_6 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000004546 160.0
WH2_k127_6432134_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 9.258e-292 917.0
WH2_k127_6432134_1 AMP-binding enzyme K01897 - 6.2.1.3 9.14e-286 897.0
WH2_k127_6432134_10 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 3.263e-211 666.0
WH2_k127_6432134_11 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.115e-205 660.0
WH2_k127_6432134_12 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.05e-203 643.0
WH2_k127_6432134_13 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 557.0
WH2_k127_6432134_14 Enolase C-terminal domain-like K22209 - 4.2.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 541.0
WH2_k127_6432134_15 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 548.0
WH2_k127_6432134_16 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 536.0
WH2_k127_6432134_17 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 524.0
WH2_k127_6432134_18 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 497.0
WH2_k127_6432134_19 Transcriptional regulator sugar kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 501.0
WH2_k127_6432134_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 9.846e-270 837.0
WH2_k127_6432134_20 carnitine dehydratase K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 487.0
WH2_k127_6432134_21 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 459.0
WH2_k127_6432134_22 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 466.0
WH2_k127_6432134_23 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 462.0
WH2_k127_6432134_24 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 429.0
WH2_k127_6432134_25 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 437.0
WH2_k127_6432134_26 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 422.0
WH2_k127_6432134_27 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 426.0
WH2_k127_6432134_28 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 408.0
WH2_k127_6432134_29 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 406.0
WH2_k127_6432134_3 Acyclic terpene utilisation family protein AtuA - - - 4.219e-252 791.0
WH2_k127_6432134_30 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 404.0
WH2_k127_6432134_31 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 379.0
WH2_k127_6432134_32 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 376.0
WH2_k127_6432134_33 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 375.0
WH2_k127_6432134_34 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 368.0
WH2_k127_6432134_35 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 335.0
WH2_k127_6432134_36 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 330.0
WH2_k127_6432134_37 N-terminal TM domain of oligopeptide transport permease C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 347.0
WH2_k127_6432134_38 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 344.0
WH2_k127_6432134_39 C-C_Bond_Lyase of the TIM-Barrel fold K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 326.0
WH2_k127_6432134_4 Sulfatase - - - 8.944e-249 777.0
WH2_k127_6432134_40 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 338.0
WH2_k127_6432134_41 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 318.0
WH2_k127_6432134_42 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 306.0
WH2_k127_6432134_43 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 296.0
WH2_k127_6432134_44 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 294.0
WH2_k127_6432134_45 Bacterial transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001661 275.0
WH2_k127_6432134_46 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007742 267.0
WH2_k127_6432134_47 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000001495 262.0
WH2_k127_6432134_48 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000003475 261.0
WH2_k127_6432134_49 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000003024 246.0
WH2_k127_6432134_5 Pfam:DUF1446 - - - 4.275e-233 736.0
WH2_k127_6432134_50 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001866 254.0
WH2_k127_6432134_51 PFAM binding-protein-dependent transport systems inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004408 246.0
WH2_k127_6432134_52 PFAM regulatory protein TetR K13770 - - 0.000000000000000000000000000000000000000000000000000000000000000000005803 241.0
WH2_k127_6432134_53 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000003883 239.0
WH2_k127_6432134_54 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000006621 249.0
WH2_k127_6432134_55 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000001444 243.0
WH2_k127_6432134_56 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000186 231.0
WH2_k127_6432134_57 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000001228 239.0
WH2_k127_6432134_58 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000000000000000000163 221.0
WH2_k127_6432134_59 Domain of unknown function (DUF4365) - - - 0.00000000000000000000000000000000000000000000000000000000000001683 226.0
WH2_k127_6432134_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.627e-229 719.0
WH2_k127_6432134_60 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000001998 228.0
WH2_k127_6432134_61 PFAM binding-protein-dependent transport systems inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000005912 232.0
WH2_k127_6432134_62 PFAM ABC transporter related K11963 - - 0.00000000000000000000000000000000000000000000000000000000001284 225.0
WH2_k127_6432134_63 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.00000000000000000000000000000000000000000000000000000000007436 214.0
WH2_k127_6432134_64 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000003881 212.0
WH2_k127_6432134_65 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000427 222.0
WH2_k127_6432134_66 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000165 210.0
WH2_k127_6432134_67 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000724 177.0
WH2_k127_6432134_68 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000002226 168.0
WH2_k127_6432134_69 of the double-stranded beta helix - - - 0.0000000000000000000000000000000000004456 147.0
WH2_k127_6432134_7 Belongs to the ABC transporter superfamily K02031,K02032 - - 1.152e-226 723.0
WH2_k127_6432134_70 Transcriptional regulator - - - 0.000000000000000000000000000000000001495 145.0
WH2_k127_6432134_71 Pyrroline-5-carboxylate reductase K00286 - 1.5.1.2 0.00000000000000000000000000000272 129.0
WH2_k127_6432134_72 Rnk N-terminus K06140 - - 0.00000000000000000000000316 108.0
WH2_k127_6432134_73 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000003465 104.0
WH2_k127_6432134_8 Aldehyde dehydrogenase family K00128 - 1.2.1.3 5.688e-213 676.0
WH2_k127_6432134_9 AMP-binding enzyme C-terminal domain - - - 3.009e-211 678.0
WH2_k127_6443567_0 Belongs to the enoyl-CoA hydratase isomerase family K00022,K07514 - 1.1.1.35,4.2.1.17,5.3.3.8 0.0 1038.0
WH2_k127_6443567_1 PFAM acyl-CoA dehydrogenase domain protein - - - 8.976e-218 680.0
WH2_k127_6443567_10 Glycerol dehydrogenase and related enzymes K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 426.0
WH2_k127_6443567_11 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 434.0
WH2_k127_6443567_12 Alkaline phosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 418.0
WH2_k127_6443567_13 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 399.0
WH2_k127_6443567_14 Binding-protein-dependent transport system inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 394.0
WH2_k127_6443567_15 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 417.0
WH2_k127_6443567_16 Putative sugar-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 376.0
WH2_k127_6443567_17 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 352.0
WH2_k127_6443567_18 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 341.0
WH2_k127_6443567_19 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 331.0
WH2_k127_6443567_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 5.706e-217 686.0
WH2_k127_6443567_20 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000002815 267.0
WH2_k127_6443567_21 PFAM Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000003647 243.0
WH2_k127_6443567_22 acetylesterase activity K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000431 229.0
WH2_k127_6443567_23 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000187 155.0
WH2_k127_6443567_24 - - - - 0.000000001545 69.0
WH2_k127_6443567_25 Belongs to the UPF0337 (CsbD) family - - - 0.00000002429 57.0
WH2_k127_6443567_3 Bacterial extracellular solute-binding protein - - - 6.46e-216 685.0
WH2_k127_6443567_4 Acyl-CoA dehydrogenase type 2 domain K00249 - 1.3.8.7 9.459e-216 693.0
WH2_k127_6443567_5 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 1.277e-202 656.0
WH2_k127_6443567_6 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 532.0
WH2_k127_6443567_7 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 521.0
WH2_k127_6443567_8 PFAM aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 493.0
WH2_k127_6443567_9 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 477.0
WH2_k127_6467558_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 586.0
WH2_k127_6467558_1 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 483.0
WH2_k127_6467558_2 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 424.0
WH2_k127_6467558_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 383.0
WH2_k127_6467558_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 314.0
WH2_k127_6467558_5 Class II aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 319.0
WH2_k127_6467558_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 289.0
WH2_k127_6467558_7 regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000003113 231.0
WH2_k127_6467558_8 ThiJ PfpI - - - 0.0000000000000000000000000000000000000000000000000000000000000004313 227.0
WH2_k127_6473873_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 327.0
WH2_k127_6473873_1 TIGRFAM general secretion pathway protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 304.0
WH2_k127_6473873_10 - K02456 - - 0.0000000000002715 77.0
WH2_k127_6473873_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001031 271.0
WH2_k127_6473873_3 AraC Family K13652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008708 260.0
WH2_k127_6473873_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009759 263.0
WH2_k127_6473873_5 Protein of unknown function (DUF1194) - - - 0.0000000000000000000000000000000000000000000000000000000002786 220.0
WH2_k127_6473873_6 Type II secretion system (T2SS), protein G - - - 0.000000000000000000000000000000000000000000000004379 178.0
WH2_k127_6473873_7 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000003983 150.0
WH2_k127_6473873_8 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000004037 150.0
WH2_k127_6473873_9 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000002147 85.0
WH2_k127_6492362_0 Major Facilitator Superfamily - - - 1.715e-198 632.0
WH2_k127_6492362_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 617.0
WH2_k127_6492362_10 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 304.0
WH2_k127_6492362_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005823 287.0
WH2_k127_6492362_12 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
WH2_k127_6492362_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000001066 209.0
WH2_k127_6492362_14 UTRA K05836 - - 0.00000000000000000000000000000000001131 138.0
WH2_k127_6492362_15 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000001024 129.0
WH2_k127_6492362_16 Dicarboxylate transport - - - 0.0000000000000000000000000000007377 141.0
WH2_k127_6492362_17 Protein of unknown function (DUF535) K09824 - - 0.00000000000000000000000000004932 131.0
WH2_k127_6492362_18 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000001066 116.0
WH2_k127_6492362_19 Rhodanese Homology Domain - - - 0.000000000000000000003235 101.0
WH2_k127_6492362_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 616.0
WH2_k127_6492362_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 576.0
WH2_k127_6492362_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 463.0
WH2_k127_6492362_5 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 433.0
WH2_k127_6492362_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 362.0
WH2_k127_6492362_7 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 364.0
WH2_k127_6492362_8 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 350.0
WH2_k127_6492362_9 Biotin-lipoyl like K03543,K15549 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 318.0
WH2_k127_6496698_0 PFAM Rieske 2Fe-2S domain protein K00479 - - 2.625e-202 637.0
WH2_k127_6496698_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 6.126e-201 632.0
WH2_k127_6496698_10 PFAM binding-protein-dependent transport systems inner membrane component K02001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 388.0
WH2_k127_6496698_11 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 383.0
WH2_k127_6496698_12 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 314.0
WH2_k127_6496698_13 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.00000000000000000000000000000000000000005117 154.0
WH2_k127_6496698_14 addiction module antidote protein - - - 0.0000000000000000000005502 109.0
WH2_k127_6496698_15 protein conserved in bacteria - - - 0.000008867 58.0
WH2_k127_6496698_2 Serine dehydratase beta chain K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 591.0
WH2_k127_6496698_3 ATPases associated with a variety of cellular activities K02000 GO:0000166,GO:0003674,GO:0004888,GO:0005034,GO:0005215,GO:0005275,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015837,GO:0015838,GO:0016020,GO:0016021,GO:0017076,GO:0022857,GO:0023052,GO:0030554,GO:0031224,GO:0031460,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0038023,GO:0043167,GO:0043168,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0060089,GO:0065007,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 577.0
WH2_k127_6496698_4 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 496.0
WH2_k127_6496698_5 ATPases associated with a variety of cellular activities K02000 - 3.6.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 496.0
WH2_k127_6496698_6 Oxidoreductase FAD-binding domain K00523,K21832 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 488.0
WH2_k127_6496698_7 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 477.0
WH2_k127_6496698_8 Binding-protein-dependent transport system inner membrane component K02001 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0008150,GO:0015695,GO:0015696,GO:0015871,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 450.0
WH2_k127_6496698_9 PFAM Substrate-binding region of ABC-type glycine betaine transport system K02002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 441.0
WH2_k127_6547581_0 ABC transporter transmembrane region - - - 0.0 1672.0
WH2_k127_6547581_1 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 388.0
WH2_k127_6547581_2 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 290.0
WH2_k127_6547581_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000005063 61.0
WH2_k127_6596984_0 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 458.0
WH2_k127_6596984_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 459.0
WH2_k127_6596984_2 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 374.0
WH2_k127_6596984_3 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 368.0
WH2_k127_6596984_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000000000006346 203.0
WH2_k127_6596984_5 Belongs to the Fur family K09823 - - 0.0000000000000000000000000000000000000000000000001692 182.0
WH2_k127_6596984_6 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000009639 180.0
WH2_k127_6596984_7 transporter K07238 - - 0.000000000000000000000000000000000000002713 155.0
WH2_k127_6622562_0 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 436.0
WH2_k127_6622562_1 Sugar (and other) transporter K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 351.0
WH2_k127_6622562_2 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 314.0
WH2_k127_6622562_3 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003915 288.0
WH2_k127_6622562_4 low-complexity proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006725 274.0
WH2_k127_6622562_5 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004444 254.0
WH2_k127_6622562_6 Branched-chain amino acid transport - - - 0.0000000000000000000000000000000009817 132.0
WH2_k127_6622562_7 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000009976 113.0
WH2_k127_6629583_0 type II secretion system protein E - - - 0.0000000000000000000000000000000000000000000000000000002343 214.0
WH2_k127_6629583_1 Type II secretory pathway, component PulD - - - 0.00000000000000000000000000000000000002179 163.0
WH2_k127_6629583_2 Type II secretion system (T2SS), protein F K10934 - - 0.0000000000000000000000000000000313 139.0
WH2_k127_6629583_3 Bacterial shufflon protein, N-terminal constant region - - - 0.00000000001851 75.0
WH2_k127_6629583_4 PFAM Type II secretion system protein E K07332 - - 0.00000000002552 76.0
WH2_k127_6629583_5 Pilin accessory protein (PilO) - - - 0.000000007381 68.0
WH2_k127_6629583_6 Bacterial conjugation TrbI-like protein K03195 - - 0.000005885 57.0
WH2_k127_6629583_7 Toxin co-regulated pilus biosynthesis protein Q - - - 0.0001312 54.0
WH2_k127_6632821_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 459.0
WH2_k127_6632821_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 407.0
WH2_k127_6632821_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000001545 70.0
WH2_k127_6655748_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 337.0
WH2_k127_6655748_1 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 338.0
WH2_k127_6655748_10 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000009855 125.0
WH2_k127_6655748_11 FR47-like protein - - - 0.0000000000006622 77.0
WH2_k127_6655748_12 Lysylphosphatidylglycerol synthase TM region - - - 0.000000002783 60.0
WH2_k127_6655748_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 329.0
WH2_k127_6655748_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 327.0
WH2_k127_6655748_4 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 323.0
WH2_k127_6655748_5 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 299.0
WH2_k127_6655748_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000129 255.0
WH2_k127_6655748_7 PFAM Methyltransferase type - - - 0.000000000000000000000000000000000000000000000000000000009793 203.0
WH2_k127_6655748_8 Phosphoglycerate mutase family K15640 - - 0.000000000000000000000000000000000000000008752 160.0
WH2_k127_6655748_9 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000000002675 147.0
WH2_k127_6662030_0 Biotin carboxylase C-terminal domain - - - 6.511e-259 819.0
WH2_k127_6662030_1 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 1.132e-207 660.0
WH2_k127_6662030_2 Biotin carboxylase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 398.0
WH2_k127_6662030_3 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 388.0
WH2_k127_6662030_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000004619 57.0
WH2_k127_6666862_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009438 469.0
WH2_k127_6666862_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 357.0
WH2_k127_6666862_2 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000005025 184.0
WH2_k127_6717677_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0 1127.0
WH2_k127_6717677_1 Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - 0.00000000000000000000000000000000000000000001294 167.0
WH2_k127_6717677_2 Protein of unknown function (DUF1465) K13592 - - 0.00000000001801 70.0
WH2_k127_6737598_0 Domain of unknown function (DUF3362) - - - 0.0 1144.0
WH2_k127_6737598_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.996e-259 804.0
WH2_k127_6737598_10 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 374.0
WH2_k127_6737598_11 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 348.0
WH2_k127_6737598_12 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 343.0
WH2_k127_6737598_13 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 339.0
WH2_k127_6737598_14 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 336.0
WH2_k127_6737598_15 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 331.0
WH2_k127_6737598_16 GntR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 321.0
WH2_k127_6737598_17 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006581 247.0
WH2_k127_6737598_18 Dehydroquinase class II K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000009379 218.0
WH2_k127_6737598_19 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000000000000000004586 233.0
WH2_k127_6737598_2 DNA polymerase IV K02346 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 538.0
WH2_k127_6737598_20 glycerophosphoryl diester phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000006517 209.0
WH2_k127_6737598_21 Domain of unknown function (DUF1849) - - - 0.0000000000000000000000000000000000000000000000000006161 194.0
WH2_k127_6737598_22 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000001054 175.0
WH2_k127_6737598_23 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000002492 123.0
WH2_k127_6737598_24 spore germination - - - 0.000000000000002828 89.0
WH2_k127_6737598_25 Fusaric acid resistance protein-like - - - 0.0000000002555 72.0
WH2_k127_6737598_3 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 489.0
WH2_k127_6737598_4 ABC-type polar amino acid transport system, ATPase component K02028,K02029,K09972 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 403.0
WH2_k127_6737598_5 ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 395.0
WH2_k127_6737598_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 398.0
WH2_k127_6737598_7 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 391.0
WH2_k127_6737598_8 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 386.0
WH2_k127_6737598_9 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 382.0
WH2_k127_6749648_0 Sigma-54 interaction domain - - - 2.379e-287 899.0
WH2_k127_6749648_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 2.258e-285 883.0
WH2_k127_6749648_10 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 492.0
WH2_k127_6749648_11 nitrate ABC transporter K02050,K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 451.0
WH2_k127_6749648_12 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 451.0
WH2_k127_6749648_13 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 437.0
WH2_k127_6749648_14 Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 417.0
WH2_k127_6749648_15 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 413.0
WH2_k127_6749648_16 Glycosyl hydrolases family 15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 413.0
WH2_k127_6749648_17 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 407.0
WH2_k127_6749648_18 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 395.0
WH2_k127_6749648_19 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 393.0
WH2_k127_6749648_2 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 4.241e-272 856.0
WH2_k127_6749648_20 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 391.0
WH2_k127_6749648_21 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 385.0
WH2_k127_6749648_22 diguanylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 391.0
WH2_k127_6749648_23 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 374.0
WH2_k127_6749648_24 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 348.0
WH2_k127_6749648_25 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 347.0
WH2_k127_6749648_26 Siderophore-interacting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 342.0
WH2_k127_6749648_27 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 338.0
WH2_k127_6749648_28 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 345.0
WH2_k127_6749648_29 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 323.0
WH2_k127_6749648_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.112e-267 850.0
WH2_k127_6749648_30 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 316.0
WH2_k127_6749648_31 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 307.0
WH2_k127_6749648_32 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002887 276.0
WH2_k127_6749648_33 Enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005848 274.0
WH2_k127_6749648_34 protein conserved in bacteria K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006738 277.0
WH2_k127_6749648_35 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004094 256.0
WH2_k127_6749648_36 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000002159 261.0
WH2_k127_6749648_37 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000007579 227.0
WH2_k127_6749648_38 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001296 229.0
WH2_k127_6749648_39 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000003628 198.0
WH2_k127_6749648_4 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 2.168e-244 771.0
WH2_k127_6749648_40 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000003843 184.0
WH2_k127_6749648_41 Serine hydrolase K07002 - - 0.0000000000000000000000000000000000000000000001331 185.0
WH2_k127_6749648_42 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000008689 164.0
WH2_k127_6749648_43 Scavenger mRNA decapping enzyme C-term binding - - - 0.000000000000000000000000000000000000000001587 159.0
WH2_k127_6749648_44 Protein of unknown function (DUF1489) - - - 0.000000000000000000000000000000000000000001983 159.0
WH2_k127_6749648_45 COG2825 Outer membrane protein - - - 0.0000000000000000000000001314 114.0
WH2_k127_6749648_46 GDYXXLXY protein - - - 0.000000000000000008974 97.0
WH2_k127_6749648_47 Protein of unknown function DUF126 - - - 0.000000000000009541 81.0
WH2_k127_6749648_48 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0000000000007919 78.0
WH2_k127_6749648_49 PFAM response regulator receiver - - - 0.00000000007374 64.0
WH2_k127_6749648_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051,K15576 - - 2.624e-240 749.0
WH2_k127_6749648_50 Predicted membrane protein (DUF2157) - - - 0.000000002153 70.0
WH2_k127_6749648_51 Belongs to the peptidase S8 family - - - 0.0003277 52.0
WH2_k127_6749648_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 566.0
WH2_k127_6749648_7 Protein of unknown function (DUF521) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 524.0
WH2_k127_6749648_8 COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 526.0
WH2_k127_6749648_9 COG0471 Di- and tricarboxylate transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 487.0
WH2_k127_6785664_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 556.0
WH2_k127_6785664_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 552.0
WH2_k127_6785664_10 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000001003 237.0
WH2_k127_6785664_11 KR domain K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000977 231.0
WH2_k127_6785664_12 DNA-binding transcription factor activity K03710 - - 0.00000000000000000000000000000000000000000000007536 178.0
WH2_k127_6785664_13 Small Multidrug Resistance protein K03297 GO:0003674,GO:0005215,GO:0005326,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006805,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006855,GO:0006950,GO:0006970,GO:0006974,GO:0008150,GO:0008152,GO:0008324,GO:0008519,GO:0009410,GO:0009628,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015101,GO:0015199,GO:0015220,GO:0015238,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015307,GO:0015318,GO:0015651,GO:0015672,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0015871,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0031460,GO:0033554,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071466,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072349,GO:0072488,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - 0.00000000000000000000000000000000000000004888 154.0
WH2_k127_6785664_14 Cold shock K03704 - - 0.000000000000000000000000000000001241 132.0
WH2_k127_6785664_15 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000385 142.0
WH2_k127_6785664_16 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000006277 127.0
WH2_k127_6785664_17 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000009095 117.0
WH2_k127_6785664_18 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000005644 95.0
WH2_k127_6785664_2 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 436.0
WH2_k127_6785664_3 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 400.0
WH2_k127_6785664_4 TIM-barrel enzyme K06971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 355.0
WH2_k127_6785664_5 Branched-chain amino acid transport system / permease component K02057,K10440,K17214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 366.0
WH2_k127_6785664_6 Calcineurin-like phosphoesterase superfamily domain K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 333.0
WH2_k127_6785664_7 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 322.0
WH2_k127_6785664_8 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004573 308.0
WH2_k127_6785664_9 belongs to the thioredoxin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005464 248.0
WH2_k127_6822804_0 PFAM binding-protein-dependent transport systems inner membrane component K02053,K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 531.0
WH2_k127_6822804_1 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 425.0
WH2_k127_6822804_2 chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 419.0
WH2_k127_6822804_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 395.0
WH2_k127_6822804_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004261 296.0
WH2_k127_6822804_5 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003471 263.0
WH2_k127_6822804_6 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000002896 220.0
WH2_k127_6822804_7 Cupin domain - - - 0.00000000000000000000000000000000000008349 151.0
WH2_k127_6822804_8 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000001573 135.0
WH2_k127_6837060_0 GMC oxidoreductase K00108 - 1.1.99.1 1.187e-302 934.0
WH2_k127_6837060_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid K00130 - 1.2.1.8 5.669e-222 692.0
WH2_k127_6837060_2 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 524.0
WH2_k127_6837060_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 444.0
WH2_k127_6837060_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 332.0
WH2_k127_6837060_5 HAD-superfamily hydrolase subfamily IA, variant K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004104 280.0
WH2_k127_6837060_6 DeoR C terminal sensor domain K02444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000069 260.0
WH2_k127_6837060_7 - - - - 0.00000002145 64.0
WH2_k127_6879468_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.564e-289 895.0
WH2_k127_6879468_1 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 423.0
WH2_k127_6879468_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 387.0
WH2_k127_6879468_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 333.0
WH2_k127_6879468_4 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 332.0
WH2_k127_6879468_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 303.0
WH2_k127_6879468_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 298.0
WH2_k127_6879468_7 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000007177 254.0
WH2_k127_6879468_8 MarC family integral membrane protein - - - 0.00000000000000000000000000000000000000000000000198 180.0
WH2_k127_6879468_9 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000000000002637 187.0
WH2_k127_6887096_0 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 501.0
WH2_k127_6887096_1 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 457.0
WH2_k127_6887096_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000001442 127.0
WH2_k127_6887096_11 SnoaL-like polyketide cyclase K15945 - - 0.00000000000008796 77.0
WH2_k127_6887096_2 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 340.0
WH2_k127_6887096_3 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002913 268.0
WH2_k127_6887096_4 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006477 238.0
WH2_k127_6887096_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000001568 228.0
WH2_k127_6887096_6 - - - - 0.00000000000000000000000000000000000000000000000000000000006639 214.0
WH2_k127_6887096_7 chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000006989 188.0
WH2_k127_6887096_8 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000001202 178.0
WH2_k127_6887096_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000001674 163.0
WH2_k127_6908225_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 7.6e-322 993.0
WH2_k127_6908225_1 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 1.189e-264 839.0
WH2_k127_6908225_10 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 330.0
WH2_k127_6908225_11 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001728 274.0
WH2_k127_6908225_12 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000006148 252.0
WH2_k127_6908225_13 transcriptional regulator K07736 - - 0.00000000000000000000000000000000000000000000000000000000000001033 233.0
WH2_k127_6908225_14 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000000102 215.0
WH2_k127_6908225_15 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000127 224.0
WH2_k127_6908225_16 transcriptional K03719 - - 0.00000000000000000000000000000000000000004182 164.0
WH2_k127_6908225_17 DNA repair protein MmcB-like - - - 0.0000000000000000000000000000000000000001737 156.0
WH2_k127_6908225_18 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.0000000000000000000000000000000000001257 145.0
WH2_k127_6908225_19 Domain of unknown function (DUF4214) - - - 0.00000000000000000000000000000000001037 159.0
WH2_k127_6908225_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 9.597e-212 672.0
WH2_k127_6908225_20 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000007052 130.0
WH2_k127_6908225_21 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.0000000000000000000000000000004601 126.0
WH2_k127_6908225_22 TM2 domain - - - 0.00000000000000000000001014 103.0
WH2_k127_6908225_23 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.00000000000000000000001588 110.0
WH2_k127_6908225_24 lactoylglutathione lyase activity - - - 0.000000000000000000001821 99.0
WH2_k127_6908225_25 - - - - 0.0000133 58.0
WH2_k127_6908225_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 7.436e-205 646.0
WH2_k127_6908225_4 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 466.0
WH2_k127_6908225_5 Bacterial periplasmic substrate-binding proteins K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 467.0
WH2_k127_6908225_6 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 457.0
WH2_k127_6908225_7 AFG1-like ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 453.0
WH2_k127_6908225_8 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 442.0
WH2_k127_6908225_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 351.0
WH2_k127_6910776_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 4.841e-276 864.0
WH2_k127_6910776_1 Uncharacterized protein family (UPF0051) K09014 - - 4.793e-256 795.0
WH2_k127_6910776_10 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 356.0
WH2_k127_6910776_11 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 332.0
WH2_k127_6910776_12 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 302.0
WH2_k127_6910776_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005924 278.0
WH2_k127_6910776_14 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005195 278.0
WH2_k127_6910776_15 2-hydroxychromene-2-carboxylate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000335 261.0
WH2_k127_6910776_16 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007062 252.0
WH2_k127_6910776_17 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000002842 226.0
WH2_k127_6910776_18 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030,K10036 - - 0.000000000000000000000000000000000000000000000000000000000000003945 233.0
WH2_k127_6910776_19 Ligand-gated ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000004285 228.0
WH2_k127_6910776_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 4.165e-224 711.0
WH2_k127_6910776_20 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000000000000000005087 207.0
WH2_k127_6910776_21 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488,K13819 - - 0.000000000000000000000000000000000000000000000000000000105 199.0
WH2_k127_6910776_22 Related to arylsulfate sulfotransferase involved in siderophore - - - 0.000000000000000000000000000000000000000000002239 166.0
WH2_k127_6910776_23 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000005858 162.0
WH2_k127_6910776_24 FeS assembly SUF system protein - - - 0.0000000000000000000000000000000000156 143.0
WH2_k127_6910776_25 Transcriptional regulator - - - 0.0000000000000000000000000000000006351 135.0
WH2_k127_6910776_26 Belongs to the ompA family - - - 0.00000000000000000000000000000006966 128.0
WH2_k127_6910776_27 - - - - 0.000000000000000000000000000000449 130.0
WH2_k127_6910776_28 Acetyltransferase (GNAT) domain K03824 - - 0.000000000000000000000000000002928 135.0
WH2_k127_6910776_29 Alpha beta hydrolase - - - 0.000000000000000000000001618 113.0
WH2_k127_6910776_3 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 559.0
WH2_k127_6910776_30 EamA-like transporter family - - - 0.0000000000000000000001391 110.0
WH2_k127_6910776_31 Histidine K01745 - 4.3.1.3 0.0000000000000000000007301 103.0
WH2_k127_6910776_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 543.0
WH2_k127_6910776_5 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 470.0
WH2_k127_6910776_6 Glycosyl transferase family 2 K00721,K10012 - 2.4.1.83,2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 452.0
WH2_k127_6910776_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 447.0
WH2_k127_6910776_8 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 394.0
WH2_k127_6910776_9 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 374.0
WH2_k127_6934768_0 - K06909 - - 2.535e-200 636.0
WH2_k127_6934768_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 390.0
WH2_k127_6934768_2 Family of unknown function (DUF5309) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001022 241.0
WH2_k127_6934768_3 - - - - 0.000000000000000000000000000000000000000000000000000000000001445 234.0
WH2_k127_6934768_4 - - - - 0.0000000000000000000000000000007905 135.0
WH2_k127_6934768_5 - - - - 0.00000000000000000000002371 107.0
WH2_k127_6934768_6 - - - - 0.00000000000000000000008444 112.0
WH2_k127_6934768_7 tail collar domain protein - - - 0.0000000000002135 84.0
WH2_k127_6934768_9 Phage-related protein, tail component - - - 0.0000001181 65.0
WH2_k127_7014060_0 PFAM Orn Lys Arg decarboxylase major region K01582,K01584 - 4.1.1.18,4.1.1.19 0.0 1151.0
WH2_k127_7014060_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.18e-278 865.0
WH2_k127_7014060_10 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000002958 218.0
WH2_k127_7014060_11 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000003817 208.0
WH2_k127_7014060_12 Gram-negative porin K08720 - - 0.00000000000000000000000000000000000000000000003306 186.0
WH2_k127_7014060_13 Methyl-accepting chemotaxis K03406 - - 0.000000000000000000000000000000000002815 149.0
WH2_k127_7014060_14 - - - - 0.000000000000000000000000000499 115.0
WH2_k127_7014060_15 N-formylglutamate amidohydrolase - - - 0.000000000000000000002948 101.0
WH2_k127_7014060_17 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0003961 46.0
WH2_k127_7014060_2 Amino acid permease K03756,K03759 - - 7.153e-239 751.0
WH2_k127_7014060_3 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 509.0
WH2_k127_7014060_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 417.0
WH2_k127_7014060_5 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 424.0
WH2_k127_7014060_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 295.0
WH2_k127_7014060_7 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 287.0
WH2_k127_7014060_8 EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 287.0
WH2_k127_7014060_9 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004534 273.0
WH2_k127_703153_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 3.468e-218 685.0
WH2_k127_703153_1 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 533.0
WH2_k127_703153_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 508.0
WH2_k127_703153_3 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 376.0
WH2_k127_703153_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 347.0
WH2_k127_703153_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 299.0
WH2_k127_703153_6 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004347 243.0
WH2_k127_703153_7 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001753 239.0
WH2_k127_703153_8 COG2867 Oligoketide cyclase lipid transport protein K18588 - - 0.0000000000000000000000000000002005 127.0
WH2_k127_7048625_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.095e-226 713.0
WH2_k127_7048625_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 5.365e-198 625.0
WH2_k127_7048625_10 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 393.0
WH2_k127_7048625_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 377.0
WH2_k127_7048625_12 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 370.0
WH2_k127_7048625_13 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 340.0
WH2_k127_7048625_14 Transcriptional regulator, LysR family K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 317.0
WH2_k127_7048625_15 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 306.0
WH2_k127_7048625_16 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 294.0
WH2_k127_7048625_17 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 310.0
WH2_k127_7048625_18 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 292.0
WH2_k127_7048625_19 KR domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000048 276.0
WH2_k127_7048625_2 Cytochrome p450 - - - 1.002e-194 618.0
WH2_k127_7048625_20 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005134 250.0
WH2_k127_7048625_21 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000507 260.0
WH2_k127_7048625_22 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000004215 229.0
WH2_k127_7048625_23 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000001335 231.0
WH2_k127_7048625_24 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000228 218.0
WH2_k127_7048625_25 Lysine transporter LysE - - - 0.000000000000000000000000000000000000000000000000000000000000486 217.0
WH2_k127_7048625_26 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000236 207.0
WH2_k127_7048625_27 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000006471 200.0
WH2_k127_7048625_28 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.000000000000000000000000000000000000000000000000006837 196.0
WH2_k127_7048625_29 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000001186 188.0
WH2_k127_7048625_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 593.0
WH2_k127_7048625_30 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000008977 186.0
WH2_k127_7048625_31 chromate transport protein K07240 - - 0.00000000000000000000000000000000000000000000001191 177.0
WH2_k127_7048625_32 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000003932 177.0
WH2_k127_7048625_33 Protein of unknown function (DUF4239) - - - 0.00000000000000000000000000000000000000000000006051 178.0
WH2_k127_7048625_34 TspO/MBR family K05770 - - 0.00000000000000000000000000000000000000000000738 168.0
WH2_k127_7048625_35 membrane protein, required for colicin V production K03558 - - 0.000000000000000000000000000000000000000005112 166.0
WH2_k127_7048625_36 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000002272 136.0
WH2_k127_7048625_37 membrane - - - 0.00000000000000000000000000000000005892 146.0
WH2_k127_7048625_38 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000006459 135.0
WH2_k127_7048625_39 marr family - - - 0.000000000000000000000000000003805 124.0
WH2_k127_7048625_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 548.0
WH2_k127_7048625_40 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000004294 104.0
WH2_k127_7048625_41 YXWGXW repeat (2 copies) - - - 0.000000000000000006517 87.0
WH2_k127_7048625_42 Protein conserved in bacteria K09956 - - 0.00000000000000002943 93.0
WH2_k127_7048625_43 YXWGXW repeat (2 copies) - - - 0.0000000000009099 74.0
WH2_k127_7048625_5 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 524.0
WH2_k127_7048625_6 Mycolic acid cyclopropane synthetase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0008825,GO:0009987,GO:0016740,GO:0016741,GO:0030258,GO:0032259,GO:0044237,GO:0044238,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 483.0
WH2_k127_7048625_7 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 470.0
WH2_k127_7048625_8 malonyl CoA-acyl carrier protein transacylase K00645,K15327 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 438.0
WH2_k127_7048625_9 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 414.0
WH2_k127_7155248_0 Tripartite tricarboxylate transporter TctA family - - - 1.155e-201 646.0
WH2_k127_7155248_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 4.523e-196 635.0
WH2_k127_7155248_10 monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 393.0
WH2_k127_7155248_11 TOBE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 366.0
WH2_k127_7155248_12 Binding-protein-dependent transport system inner membrane component K15554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 361.0
WH2_k127_7155248_13 monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 379.0
WH2_k127_7155248_14 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 357.0
WH2_k127_7155248_15 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 340.0
WH2_k127_7155248_16 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 332.0
WH2_k127_7155248_17 PFAM ABC transporter K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 317.0
WH2_k127_7155248_18 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 328.0
WH2_k127_7155248_19 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 303.0
WH2_k127_7155248_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 559.0
WH2_k127_7155248_20 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003038 293.0
WH2_k127_7155248_21 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001415 303.0
WH2_k127_7155248_22 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007773 270.0
WH2_k127_7155248_23 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007415 259.0
WH2_k127_7155248_24 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001512 246.0
WH2_k127_7155248_25 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000006914 245.0
WH2_k127_7155248_26 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000005244 232.0
WH2_k127_7155248_27 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050,K15554 - - 0.0000000000000000000000000000000000000000000000000000002252 202.0
WH2_k127_7155248_28 FCD - - - 0.0000000000000000000000000000000000000000000000002113 185.0
WH2_k127_7155248_29 transcriptional regulator K17737 - - 0.00000000000000000000000000000000000000000000001451 184.0
WH2_k127_7155248_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 552.0
WH2_k127_7155248_30 N-terminal TM domain of oligopeptide transport permease C - - - 0.00000000000000000000000000000000000000000000009055 170.0
WH2_k127_7155248_31 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000001223 171.0
WH2_k127_7155248_32 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000001531 96.0
WH2_k127_7155248_33 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000004626 77.0
WH2_k127_7155248_4 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 544.0
WH2_k127_7155248_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 505.0
WH2_k127_7155248_6 Luciferase-like monooxygenase K09018,K17228 - 1.14.14.35,1.14.99.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 491.0
WH2_k127_7155248_7 FAD-NAD(P)-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 468.0
WH2_k127_7155248_8 ABC transporter, phosphonate, periplasmic substrate-binding protein K15553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 421.0
WH2_k127_7155248_9 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 394.0
WH2_k127_7166152_0 Belongs to the GcvT family K00302 - 1.5.3.1 2.917e-209 674.0
WH2_k127_7166152_1 Aminotransferase class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 611.0
WH2_k127_7166152_10 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000001906 64.0
WH2_k127_7166152_2 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 518.0
WH2_k127_7166152_3 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 404.0
WH2_k127_7166152_4 hydrolases of the HAD superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 336.0
WH2_k127_7166152_5 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001328 261.0
WH2_k127_7166152_6 COG0558 Phosphatidylglycerophosphate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006222 238.0
WH2_k127_7166152_7 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000004022 225.0
WH2_k127_7166152_8 Sarcosine oxidase, gamma subunit K00305 - 1.5.3.1 0.0000000000000000005727 94.0
WH2_k127_7166152_9 heavy metal transport detoxification protein K07213 - - 0.0000000000107 69.0
WH2_k127_7181062_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1059.0
WH2_k127_7181062_1 AMP-binding enzyme C-terminal domain - - - 8.835e-230 723.0
WH2_k127_7181062_2 Belongs to the FGGY kinase family K00854 - 2.7.1.17 5.441e-212 684.0
WH2_k127_7181062_3 Alcohol dehydrogenase GroES-like domain - - - 9.031e-194 609.0
WH2_k127_7181062_4 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 540.0
WH2_k127_7181062_5 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 334.0
WH2_k127_7181062_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000006795 211.0
WH2_k127_7181062_7 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000127 150.0
WH2_k127_722169_0 Heat shock 70 kDa protein K04043 - - 0.0 1009.0
WH2_k127_722169_1 Belongs to the glutamate synthase family - - - 1.979e-278 869.0
WH2_k127_722169_10 3-dehydroquinate synthase K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 548.0
WH2_k127_722169_11 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 533.0
WH2_k127_722169_12 Belongs to the binding-protein-dependent transport system permease family K10547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 550.0
WH2_k127_722169_13 PepSY-associated TM region K00380 - 1.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 537.0
WH2_k127_722169_14 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 538.0
WH2_k127_722169_15 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 532.0
WH2_k127_722169_16 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 530.0
WH2_k127_722169_17 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 483.0
WH2_k127_722169_18 Transporter associated domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 475.0
WH2_k127_722169_19 Phytoene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 471.0
WH2_k127_722169_2 ATPases associated with a variety of cellular activities K10548 - 3.6.3.17 7.374e-237 741.0
WH2_k127_722169_20 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 466.0
WH2_k127_722169_21 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 426.0
WH2_k127_722169_22 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 453.0
WH2_k127_722169_23 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 428.0
WH2_k127_722169_24 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 433.0
WH2_k127_722169_25 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 428.0
WH2_k127_722169_26 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 410.0
WH2_k127_722169_27 sulfate adenylyltransferase (ATP) activity K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 393.0
WH2_k127_722169_28 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 394.0
WH2_k127_722169_29 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 389.0
WH2_k127_722169_3 DegT/DnrJ/EryC1/StrS aminotransferase family K01740 - 2.5.1.49 1.073e-231 724.0
WH2_k127_722169_30 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 379.0
WH2_k127_722169_31 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 386.0
WH2_k127_722169_32 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 385.0
WH2_k127_722169_33 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 367.0
WH2_k127_722169_34 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 367.0
WH2_k127_722169_35 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 362.0
WH2_k127_722169_36 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 362.0
WH2_k127_722169_37 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 364.0
WH2_k127_722169_38 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 334.0
WH2_k127_722169_39 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 342.0
WH2_k127_722169_4 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 9.426e-214 681.0
WH2_k127_722169_40 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 347.0
WH2_k127_722169_41 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 323.0
WH2_k127_722169_42 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 336.0
WH2_k127_722169_43 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 321.0
WH2_k127_722169_44 DNA methylase K00571,K07319 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 326.0
WH2_k127_722169_45 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 317.0
WH2_k127_722169_46 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 310.0
WH2_k127_722169_47 Oxidoreductase family, NAD-binding Rossmann fold K00035 - 1.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 323.0
WH2_k127_722169_48 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 326.0
WH2_k127_722169_49 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 291.0
WH2_k127_722169_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.184e-213 679.0
WH2_k127_722169_50 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 300.0
WH2_k127_722169_51 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005877 284.0
WH2_k127_722169_52 RarD protein K05786 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007028 282.0
WH2_k127_722169_53 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001317 279.0
WH2_k127_722169_54 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002016 276.0
WH2_k127_722169_55 Transcriptional regulator K02529,K05499 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008204 276.0
WH2_k127_722169_56 COG2202 FOG PAS PAC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009029 271.0
WH2_k127_722169_57 Lysine methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001011 273.0
WH2_k127_722169_58 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000005936 259.0
WH2_k127_722169_59 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009534 261.0
WH2_k127_722169_6 Cobalamin synthesis protein cobW C-terminal domain - - - 2.842e-205 644.0
WH2_k127_722169_60 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003235 256.0
WH2_k127_722169_61 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000004938 245.0
WH2_k127_722169_62 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000001307 257.0
WH2_k127_722169_63 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000153 237.0
WH2_k127_722169_64 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000401 216.0
WH2_k127_722169_65 CreA protein K05805 - - 0.00000000000000000000000000000000000000000000000000000000007777 207.0
WH2_k127_722169_66 COG0784 FOG CheY-like receiver - - - 0.00000000000000000000000000000000000000000000000000008563 196.0
WH2_k127_722169_67 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.00000000000000000000000000000000000000000000000003936 187.0
WH2_k127_722169_68 Pyrimidine 5'-nucleotidase K07025 - - 0.0000000000000000000000000000000000000000000001725 190.0
WH2_k127_722169_69 Esterase-like activity of phytase - - - 0.000000000000000000000000000000000000000000008386 184.0
WH2_k127_722169_7 Anticodon binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 559.0
WH2_k127_722169_70 Protein of unknown function (DUF1826) - - - 0.00000000000000000000000000000000000000000003208 181.0
WH2_k127_722169_71 - - - - 0.000000000000000000000000000000000000003924 166.0
WH2_k127_722169_72 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000002172 157.0
WH2_k127_722169_73 - - - - 0.0000000000000000000000000000000000003162 156.0
WH2_k127_722169_74 - - - - 0.000000000000000000000000000000000003313 152.0
WH2_k127_722169_75 Gram-negative porin K08720 - - 0.00000000000000000000000000000000001075 152.0
WH2_k127_722169_76 Integral membrane protein (DUF2244) - - - 0.00000000000000000000000000000002349 145.0
WH2_k127_722169_77 Belongs to the BolA IbaG family K05527,K22066 - - 0.00000000000000000000000000000004523 126.0
WH2_k127_722169_78 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000002117 122.0
WH2_k127_722169_79 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000003493 118.0
WH2_k127_722169_8 transport system, periplasmic component K10543,K10546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 570.0
WH2_k127_722169_80 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000001663 103.0
WH2_k127_722169_81 Antidote-toxin recognition MazE, bacterial antitoxin - - - 0.0000000000000000000002882 96.0
WH2_k127_722169_82 - - - - 0.0000000000000000001148 92.0
WH2_k127_722169_83 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000006006 89.0
WH2_k127_722169_84 phosphorelay signal transduction system - - - 0.000000000000007891 81.0
WH2_k127_722169_85 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000002891 74.0
WH2_k127_722169_9 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 548.0
WH2_k127_7245914_0 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 458.0
WH2_k127_7245914_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 343.0
WH2_k127_7245914_2 Succinylglutamate desuccinylase aspartoacylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 295.0
WH2_k127_7343170_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.389e-211 664.0
WH2_k127_7343170_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 472.0
WH2_k127_7343170_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 384.0
WH2_k127_7343170_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 355.0
WH2_k127_7343170_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000001925 265.0
WH2_k127_7343170_5 Protein of unknown function (DUF5131) - - - 0.000000000000000000000000000000000000000615 161.0
WH2_k127_737216_0 Amidohydrolase family - - - 0.0 1097.0
WH2_k127_737216_1 Major facilitator superfamily MFS_1 - - - 1.024e-197 633.0
WH2_k127_737216_10 Protein of unknown function (DUF1427) - - - 0.000000000000000000000000000000002619 130.0
WH2_k127_737216_11 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000002741 145.0
WH2_k127_737216_12 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000008026 119.0
WH2_k127_737216_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 614.0
WH2_k127_737216_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 389.0
WH2_k127_737216_4 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 379.0
WH2_k127_737216_5 Uncharacterized protein conserved in bacteria (DUF2239) K09965 - - 0.00000000000000000000000000000000000000000000000000000000000000000008862 235.0
WH2_k127_737216_6 Peptide methionine sulfoxide reductase B1, chloroplastic-like K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000016 242.0
WH2_k127_737216_7 PFAM DoxX family protein - - - 0.000000000000000000000000000000000000000000004114 167.0
WH2_k127_737216_8 periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000005345 158.0
WH2_k127_737216_9 Transcriptional regulator - - - 0.000000000000000000000000000000000002705 141.0
WH2_k127_7421340_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1184.0
WH2_k127_7421340_1 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.49e-252 799.0
WH2_k127_7421340_10 Belongs to the HpcH HpaI aldolase family K08691 - 4.1.3.24,4.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 539.0
WH2_k127_7421340_11 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 550.0
WH2_k127_7421340_12 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 473.0
WH2_k127_7421340_13 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 435.0
WH2_k127_7421340_14 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 426.0
WH2_k127_7421340_15 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 424.0
WH2_k127_7421340_16 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 421.0
WH2_k127_7421340_17 KR domain K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 396.0
WH2_k127_7421340_18 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 417.0
WH2_k127_7421340_19 Epoxide hydrolase N terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 377.0
WH2_k127_7421340_2 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 3.45e-210 662.0
WH2_k127_7421340_20 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 363.0
WH2_k127_7421340_21 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 358.0
WH2_k127_7421340_22 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 340.0
WH2_k127_7421340_23 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 313.0
WH2_k127_7421340_24 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 308.0
WH2_k127_7421340_25 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000175 274.0
WH2_k127_7421340_26 PFAM Mo-dependent nitrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006079 272.0
WH2_k127_7421340_27 TOBE domain K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000225 267.0
WH2_k127_7421340_28 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000001925 234.0
WH2_k127_7421340_29 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000001647 225.0
WH2_k127_7421340_3 Belongs to the thiolase family K00626 - 2.3.1.9 2.791e-208 653.0
WH2_k127_7421340_30 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000001664 207.0
WH2_k127_7421340_31 Thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000002263 193.0
WH2_k127_7421340_32 - - - - 0.00000000000000000000000000000000000000000000000007253 192.0
WH2_k127_7421340_33 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000109 184.0
WH2_k127_7421340_34 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000002237 198.0
WH2_k127_7421340_35 - - - - 0.000000000000000000000000000000000000000000005183 176.0
WH2_k127_7421340_36 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000009926 179.0
WH2_k127_7421340_37 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000002574 147.0
WH2_k127_7421340_38 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000001972 141.0
WH2_k127_7421340_39 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000004394 141.0
WH2_k127_7421340_4 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 1.375e-199 650.0
WH2_k127_7421340_40 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000533 122.0
WH2_k127_7421340_41 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000008005 120.0
WH2_k127_7421340_42 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000106 118.0
WH2_k127_7421340_43 Outer membrane protein beta-barrel domain - - - 0.00000000000000000002129 100.0
WH2_k127_7421340_44 PAS domain - - - 0.000000000000000000158 104.0
WH2_k127_7421340_45 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000002291 92.0
WH2_k127_7421340_46 Beta-1,3-glucanase - - - 0.000000001907 72.0
WH2_k127_7421340_5 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 8.98e-198 622.0
WH2_k127_7421340_6 AP endonuclease family 2 C terminus - - - 2.485e-196 616.0
WH2_k127_7421340_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 9.621e-196 615.0
WH2_k127_7421340_8 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 583.0
WH2_k127_7421340_9 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 581.0
WH2_k127_744842_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.647e-273 846.0
WH2_k127_744842_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 547.0
WH2_k127_744842_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 388.0
WH2_k127_744842_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000001405 204.0
WH2_k127_744842_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000009112 96.0
WH2_k127_7504038_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 588.0
WH2_k127_7504038_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 519.0
WH2_k127_7504038_10 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000008875 215.0
WH2_k127_7504038_11 FlgJ-related protein K03796 - - 0.00000000000000000000000000000000000000000000000000000005846 210.0
WH2_k127_7504038_12 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000000000000000000000000000000003387 190.0
WH2_k127_7504038_13 universal stress protein UspA and related nucleotide-binding - - - 0.00000000000000000000000000000000000000004363 156.0
WH2_k127_7504038_14 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000007137 132.0
WH2_k127_7504038_15 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000009858 116.0
WH2_k127_7504038_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 488.0
WH2_k127_7504038_3 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 406.0
WH2_k127_7504038_4 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 355.0
WH2_k127_7504038_5 xylanase chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 310.0
WH2_k127_7504038_6 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 302.0
WH2_k127_7504038_7 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002456 271.0
WH2_k127_7504038_8 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006897 271.0
WH2_k127_7504038_9 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000001633 251.0
WH2_k127_7514748_0 TIGRFAM ATP-dependent DNA helicase, RecQ K03654 - 3.6.4.12 1.846e-266 832.0
WH2_k127_7514748_1 belongs to the aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 6.795e-212 681.0
WH2_k127_7514748_10 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 331.0
WH2_k127_7514748_11 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 314.0
WH2_k127_7514748_12 NMT1-like family K02051,K15553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 317.0
WH2_k127_7514748_13 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 308.0
WH2_k127_7514748_14 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005074 290.0
WH2_k127_7514748_15 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006861 267.0
WH2_k127_7514748_16 Domain of unknown function DUF108 K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000004289 244.0
WH2_k127_7514748_17 Bacterial transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000002598 229.0
WH2_k127_7514748_18 Rifampin ADP-ribosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000099 221.0
WH2_k127_7514748_19 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000005979 209.0
WH2_k127_7514748_2 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 6.264e-209 657.0
WH2_k127_7514748_20 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000006198 179.0
WH2_k127_7514748_21 - - - - 0.000000000000000000000000000000000000000000000001945 175.0
WH2_k127_7514748_22 Translation initiation inhibitor - - - 0.0000000000000000000000000000000004388 135.0
WH2_k127_7514748_23 - - - - 0.00000000000000001164 89.0
WH2_k127_7514748_3 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 572.0
WH2_k127_7514748_4 NADH flavin oxidoreductase NADH oxidase K10680 GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 529.0
WH2_k127_7514748_5 PFAM Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 523.0
WH2_k127_7514748_6 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 451.0
WH2_k127_7514748_7 2Fe-2S iron-sulfur cluster binding domain K21607 - 1.1.1.404 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 347.0
WH2_k127_7514748_8 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 341.0
WH2_k127_7514748_9 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 326.0
WH2_k127_7570141_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15584 - - 3.939e-287 889.0
WH2_k127_7570141_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15584 - - 4.455e-281 871.0
WH2_k127_7570141_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 324.0
WH2_k127_7570141_11 amino acid transport K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001698 289.0
WH2_k127_7570141_12 PFAM ABC transporter K10008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000905 279.0
WH2_k127_7570141_13 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001252 252.0
WH2_k127_7570141_14 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002418 259.0
WH2_k127_7570141_15 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000001392 213.0
WH2_k127_7570141_16 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000003392 199.0
WH2_k127_7570141_17 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.00000000000000000000000000000000000017 158.0
WH2_k127_7570141_18 Glutamine ABC transporter permease K10040 - - 0.0000000000000000000000000000001576 133.0
WH2_k127_7570141_19 Elongation factor SelB, winged helix K03833 - - 0.0000004604 56.0
WH2_k127_7570141_2 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13892,K13896,K15583 - - 7.453e-251 794.0
WH2_k127_7570141_20 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0007745 42.0
WH2_k127_7570141_3 Luciferase-like monooxygenase - - - 1.376e-229 721.0
WH2_k127_7570141_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 3.461e-224 706.0
WH2_k127_7570141_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 492.0
WH2_k127_7570141_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 464.0
WH2_k127_7570141_7 Monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 470.0
WH2_k127_7570141_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 423.0
WH2_k127_7570141_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 364.0
WH2_k127_7575050_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 2.672e-237 744.0
WH2_k127_7575050_1 Amidohydrolase family - - - 2.213e-220 696.0
WH2_k127_7575050_10 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 475.0
WH2_k127_7575050_11 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 486.0
WH2_k127_7575050_12 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 464.0
WH2_k127_7575050_13 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 439.0
WH2_k127_7575050_14 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 415.0
WH2_k127_7575050_15 Branched-chain amino acid transport system / permease component K02057,K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 423.0
WH2_k127_7575050_16 Belongs to the binding-protein-dependent transport system permease family K01998,K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 380.0
WH2_k127_7575050_17 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 373.0
WH2_k127_7575050_18 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 378.0
WH2_k127_7575050_19 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 352.0
WH2_k127_7575050_2 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 4.067e-210 671.0
WH2_k127_7575050_20 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 334.0
WH2_k127_7575050_21 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 334.0
WH2_k127_7575050_22 Periplasmic binding protein domain K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 327.0
WH2_k127_7575050_23 ABC transporter K01995,K11962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 309.0
WH2_k127_7575050_24 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 297.0
WH2_k127_7575050_25 Transcriptional regulator family protein 33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001178 271.0
WH2_k127_7575050_26 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006418 253.0
WH2_k127_7575050_27 KDPG and KHG aldolase K01631 - 4.1.2.21 0.0000000000000000000000000000000000000000000000000000000000000000002116 243.0
WH2_k127_7575050_28 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002387 246.0
WH2_k127_7575050_29 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001041 242.0
WH2_k127_7575050_3 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 604.0
WH2_k127_7575050_30 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.00000000000000000000000000000000000000000000000000000000000002234 225.0
WH2_k127_7575050_31 histidine kinase HAMP region domain protein K05962,K07675 - 2.7.13.1,2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000663 225.0
WH2_k127_7575050_32 Putative stress-induced transcription regulator - - - 0.0000000000000000000000000000000000000000000000000000000003445 213.0
WH2_k127_7575050_33 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000008163 207.0
WH2_k127_7575050_34 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000001114 169.0
WH2_k127_7575050_35 Protein conserved in bacteria K09938 - - 0.00000000000000000000000000000000000000000001086 173.0
WH2_k127_7575050_36 PFAM BFD domain protein 2Fe-2S -binding domain protein K10815 - 1.4.99.5 0.0000000000000000000000000000000000002825 144.0
WH2_k127_7575050_37 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000003905 121.0
WH2_k127_7575050_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 529.0
WH2_k127_7575050_5 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 533.0
WH2_k127_7575050_6 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 511.0
WH2_k127_7575050_7 Flotillin K07192 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 514.0
WH2_k127_7575050_8 PFAM SMP-30 Gluconolaconase LRE domain protein K01053,K14274 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 494.0
WH2_k127_7575050_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 473.0
WH2_k127_7576653_0 Catalase K03781 - 1.11.1.6 3.764e-284 890.0
WH2_k127_7576653_1 Alanine-glyoxylate amino-transferase K00375,K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 526.0
WH2_k127_7576653_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 444.0
WH2_k127_7576653_3 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 421.0
WH2_k127_7576653_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 368.0
WH2_k127_7576653_5 rRNA methylase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 325.0
WH2_k127_7576653_6 Pfam:Methyltransf_6 K02553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000132 276.0
WH2_k127_7576653_7 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000000001898 215.0
WH2_k127_7578349_0 AMP-binding enzyme C-terminal domain K00666,K12507 - - 2.5e-258 807.0
WH2_k127_7578349_1 Amidase K01426 - 3.5.1.4 1.734e-251 785.0
WH2_k127_7578349_2 PFAM AMP-dependent synthetase and ligase K01911,K12508 - 6.2.1.26,6.2.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 565.0
WH2_k127_7578349_3 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 401.0
WH2_k127_7578349_4 Cephalosporin hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 369.0
WH2_k127_7578349_5 Class II aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 345.0
WH2_k127_7578349_6 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 340.0
WH2_k127_7578349_7 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000004123 220.0
WH2_k127_7594255_0 Adenylate cyclase - - - 3.652e-203 649.0
WH2_k127_7594255_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 574.0
WH2_k127_7594255_10 Integral membrane protein TerC family - - - 0.00000000028 73.0
WH2_k127_7594255_11 helix_turn_helix, Lux Regulon - - - 0.0000004049 60.0
WH2_k127_7594255_12 Resolvase - - - 0.00000302 52.0
WH2_k127_7594255_2 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 557.0
WH2_k127_7594255_3 Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 357.0
WH2_k127_7594255_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 362.0
WH2_k127_7594255_5 Belongs to the UPF0753 family K09822 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 309.0
WH2_k127_7594255_6 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002245 291.0
WH2_k127_7594255_7 VirC1 protein K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000002277 241.0
WH2_k127_7594255_8 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000007108 136.0
WH2_k127_7594255_9 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000003775 126.0
WH2_k127_7620038_0 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 512.0
WH2_k127_7620038_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000004556 199.0
WH2_k127_7620038_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000001852 134.0
WH2_k127_7621668_0 Belongs to the DapA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 568.0
WH2_k127_7621668_1 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 577.0
WH2_k127_7621668_10 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000006278 147.0
WH2_k127_7621668_11 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000009878 102.0
WH2_k127_7621668_12 histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000001645 98.0
WH2_k127_7621668_13 EamA-like transporter family - - - 0.000000002142 59.0
WH2_k127_7621668_14 EamA-like transporter family - - - 0.0001075 47.0
WH2_k127_7621668_2 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 516.0
WH2_k127_7621668_3 PFAM ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 434.0
WH2_k127_7621668_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 401.0
WH2_k127_7621668_5 Transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 313.0
WH2_k127_7621668_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 292.0
WH2_k127_7621668_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001539 260.0
WH2_k127_7621668_8 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000001051 173.0
WH2_k127_7621668_9 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.000000000000000000000000000000000000000004146 167.0
WH2_k127_7656642_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 565.0
WH2_k127_7656642_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 441.0
WH2_k127_7656642_2 ATPase (AAA K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 428.0
WH2_k127_7656642_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 381.0
WH2_k127_7656642_4 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000002288 174.0
WH2_k127_7656642_5 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000000004051 139.0
WH2_k127_7656642_6 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000001195 138.0
WH2_k127_7674729_0 Ftsk_gamma K03466 - - 6.321e-257 811.0
WH2_k127_7674729_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.492e-203 638.0
WH2_k127_7674729_10 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 428.0
WH2_k127_7674729_11 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 392.0
WH2_k127_7674729_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 372.0
WH2_k127_7674729_13 Signal transduction histidine kinase K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 378.0
WH2_k127_7674729_14 Putative S-adenosyl-L-methionine-dependent methyltransferase K00574,K18164 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 380.0
WH2_k127_7674729_15 poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 319.0
WH2_k127_7674729_16 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 310.0
WH2_k127_7674729_17 Cytochrome C1 family K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 320.0
WH2_k127_7674729_18 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 298.0
WH2_k127_7674729_19 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 297.0
WH2_k127_7674729_2 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate K11103 - - 4.134e-197 632.0
WH2_k127_7674729_20 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255 285.0
WH2_k127_7674729_21 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002456 271.0
WH2_k127_7674729_22 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006648 271.0
WH2_k127_7674729_23 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000242 254.0
WH2_k127_7674729_24 Helix-turn-helix domain, rpiR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004169 253.0
WH2_k127_7674729_25 Protein of unknown function (DUF1285) K09986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001694 246.0
WH2_k127_7674729_26 Homocysteine S-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000427 253.0
WH2_k127_7674729_27 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal K00411 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000007422 236.0
WH2_k127_7674729_28 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004983 237.0
WH2_k127_7674729_29 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000000000000000001144 230.0
WH2_k127_7674729_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 558.0
WH2_k127_7674729_30 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000002543 224.0
WH2_k127_7674729_31 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000586 224.0
WH2_k127_7674729_32 Putative bacterial sensory transduction regulator - - - 0.0000000000000000000000000000000000000000000000000000000000008484 214.0
WH2_k127_7674729_33 protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000008869 229.0
WH2_k127_7674729_34 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000669 206.0
WH2_k127_7674729_35 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000001796 204.0
WH2_k127_7674729_36 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000002219 201.0
WH2_k127_7674729_37 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000000000000009073 199.0
WH2_k127_7674729_38 YjbR - - - 0.000000000000000000000000000000000000000000004712 180.0
WH2_k127_7674729_39 PAS domain - - - 0.0000000000000000000000000000000000000000000424 165.0
WH2_k127_7674729_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 549.0
WH2_k127_7674729_40 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000006566 157.0
WH2_k127_7674729_41 - - - - 0.00000000000000000000000000000002139 137.0
WH2_k127_7674729_42 Membrane fusogenic activity K09806 - - 0.0000000000000000002917 93.0
WH2_k127_7674729_43 Ribbon-helix-helix domain - - - 0.00000000000000001359 85.0
WH2_k127_7674729_44 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000005317 77.0
WH2_k127_7674729_45 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00001271 50.0
WH2_k127_7674729_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 503.0
WH2_k127_7674729_6 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 475.0
WH2_k127_7674729_7 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 - 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 453.0
WH2_k127_7674729_8 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 454.0
WH2_k127_7674729_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 428.0
WH2_k127_768103_0 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 448.0
WH2_k127_768103_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19743 - 1.5.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 344.0
WH2_k127_768103_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 356.0
WH2_k127_768103_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 355.0
WH2_k127_768103_4 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 266.0
WH2_k127_768103_5 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000009118 237.0
WH2_k127_768103_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000001205 160.0
WH2_k127_768103_7 Zinc-finger domain - - - 0.00000000000001318 75.0
WH2_k127_768103_8 Lipopolysaccharide assembly protein A domain - - - 0.00001306 51.0
WH2_k127_7732813_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.85e-279 876.0
WH2_k127_7732813_1 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 1.683e-218 688.0
WH2_k127_7732813_2 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 587.0
WH2_k127_7732813_3 GTPase subunit of restriction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 487.0
WH2_k127_7732813_4 Male sterility protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 305.0
WH2_k127_7732813_5 May nick specific sequences that contain T G mispairs resulting from m5C-deamination K07458 - - 0.0000000000000000000000000000000000000000000000009688 179.0
WH2_k127_7734432_0 type VI secretion protein K11900 - - 2.921e-218 687.0
WH2_k127_7734432_1 ImcF-related N-terminal domain K11891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009358 310.0
WH2_k127_7734432_2 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007681 254.0
WH2_k127_7734432_3 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000000002465 207.0
WH2_k127_7734432_4 ImpA, N-terminal, type VI secretion system K11902 - - 0.00000000000000000000000000000000000000000000000000000267 211.0
WH2_k127_7734432_5 Type VI secretion system protein DotU K11892 - - 0.000000000000000000000000359 115.0
WH2_k127_7734432_6 - K11918 - - 0.00000000000000000001082 98.0
WH2_k127_7734432_7 Type VI secretion system effector, Hcp K11903 - - 0.00000001066 61.0
WH2_k127_7748860_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07303 - 1.3.99.16 0.0 1126.0
WH2_k127_7748860_1 Belongs to the GcvT family K00302 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.3.1 6.178e-260 837.0
WH2_k127_7748860_10 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 510.0
WH2_k127_7748860_11 Nitrilotriacetate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 491.0
WH2_k127_7748860_12 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 454.0
WH2_k127_7748860_13 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 430.0
WH2_k127_7748860_14 Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 410.0
WH2_k127_7748860_15 Belongs to the short-chain dehydrogenases reductases (SDR) family K14189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 396.0
WH2_k127_7748860_16 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 398.0
WH2_k127_7748860_17 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 393.0
WH2_k127_7748860_18 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 389.0
WH2_k127_7748860_19 ABC-type dipeptide oligopeptide nickel transport systems, permease K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 322.0
WH2_k127_7748860_2 Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.744e-221 691.0
WH2_k127_7748860_20 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 301.0
WH2_k127_7748860_21 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000006231 263.0
WH2_k127_7748860_22 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002687 255.0
WH2_k127_7748860_23 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000008137 252.0
WH2_k127_7748860_24 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000002067 220.0
WH2_k127_7748860_25 transcriptional regulator K02624 - - 0.0000000000000000000000000000000000000000000000000000000000001586 223.0
WH2_k127_7748860_26 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000001971 199.0
WH2_k127_7748860_27 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000005922 203.0
WH2_k127_7748860_28 Glutathione S-transferase, C-terminal domain K11209 - - 0.0000000000000000000000000000000000000000000705 168.0
WH2_k127_7748860_29 Transcriptional regulator - - - 0.000000000000000000000000000000000000000002244 172.0
WH2_k127_7748860_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 1.253e-210 670.0
WH2_k127_7748860_30 Sarcosine oxidase, delta subunit family K00304 - 1.5.3.1 0.000000000000000001799 98.0
WH2_k127_7748860_31 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000001198 79.0
WH2_k127_7748860_32 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.0004737 49.0
WH2_k127_7748860_4 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 587.0
WH2_k127_7748860_5 FAD dependent oxidoreductase K22084 - 1.5.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 597.0
WH2_k127_7748860_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 560.0
WH2_k127_7748860_7 COG0625 Glutathione S-transferase K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 541.0
WH2_k127_7748860_8 helix-turn-helix- domain containing protein AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 519.0
WH2_k127_7748860_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 519.0
WH2_k127_775469_0 PAS fold - - - 1.498e-261 822.0
WH2_k127_775469_1 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 5.205e-246 767.0
WH2_k127_775469_10 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 392.0
WH2_k127_775469_11 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 377.0
WH2_k127_775469_12 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 375.0
WH2_k127_775469_13 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 390.0
WH2_k127_775469_14 Ring hydroxylating alpha subunit (catalytic domain) K00479,K16319 - 1.14.12.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 351.0
WH2_k127_775469_15 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406,K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 355.0
WH2_k127_775469_16 Ferritin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 330.0
WH2_k127_775469_17 Flavodoxin-like fold K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 309.0
WH2_k127_775469_18 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 304.0
WH2_k127_775469_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003834 254.0
WH2_k127_775469_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 7.414e-222 695.0
WH2_k127_775469_20 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000469 233.0
WH2_k127_775469_21 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000009733 249.0
WH2_k127_775469_22 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000001334 181.0
WH2_k127_775469_23 gaf domain - - - 0.000000000000000000000000000000000000000000002972 177.0
WH2_k127_775469_24 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000001118 149.0
WH2_k127_775469_25 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000004061 125.0
WH2_k127_775469_3 Glycine D-amino acid oxidases (deaminating) K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 626.0
WH2_k127_775469_4 Belongs to the proline racemase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 556.0
WH2_k127_775469_5 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 492.0
WH2_k127_775469_6 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 477.0
WH2_k127_775469_7 TatD related DNase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 484.0
WH2_k127_775469_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 454.0
WH2_k127_775469_9 Ferritin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 417.0
WH2_k127_7757866_0 SIS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 409.0
WH2_k127_7757866_1 Phosphorylase superfamily K00757 - 2.4.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 378.0
WH2_k127_7757866_2 pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 343.0
WH2_k127_7757866_3 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 302.0
WH2_k127_7757866_4 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000001616 190.0
WH2_k127_7757866_5 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000004328 61.0
WH2_k127_7780516_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 440.0
WH2_k127_7780516_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 396.0
WH2_k127_7780516_10 clavaminate synthase activity K00471 - 1.14.11.1 0.000000000000000000000000000001634 131.0
WH2_k127_7780516_11 - - - - 0.00000000000000000000000005171 113.0
WH2_k127_7780516_12 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000002441 58.0
WH2_k127_7780516_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 396.0
WH2_k127_7780516_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 321.0
WH2_k127_7780516_4 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 301.0
WH2_k127_7780516_5 ABC transporter ATP-binding protein K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 293.0
WH2_k127_7780516_6 COG2199 FOG GGDEF domain K13590 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 296.0
WH2_k127_7780516_7 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000744 287.0
WH2_k127_7780516_8 Ferredoxin K04755 - - 0.0000000000000000000000000000000000000000000000000004275 186.0
WH2_k127_7780516_9 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.00000000000000000000000000000003096 128.0
WH2_k127_7791741_0 homoserine dehydrogenase - - - 1.594e-198 629.0
WH2_k127_7791741_1 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 1.729e-197 623.0
WH2_k127_7791741_2 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 485.0
WH2_k127_7791741_3 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 461.0
WH2_k127_7791741_4 Copper resistance protein D K07245 - - 0.0000000000000000000000000000000000000000000000000000001085 214.0
WH2_k127_7791741_5 Domain of unkown function (DUF1775) K09796 - - 0.000000000000000000000000000000000000000000000000002344 188.0
WH2_k127_7791741_6 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000004493 156.0
WH2_k127_7791741_7 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000001094 155.0
WH2_k127_7791741_8 FCD - - - 0.0000000000000000000000000001823 119.0
WH2_k127_7805739_0 Cysteine synthase K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 505.0
WH2_k127_7805739_1 cobalamin biosynthesis protein CobW K02234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 478.0
WH2_k127_7805739_2 CobN/Magnesium Chelatase K02230 - 6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 361.0
WH2_k127_7805739_3 cobalt transporter subunit CbtA - - - 0.000000000000000000000000000000000000000000000000000002186 199.0
WH2_k127_7805739_4 Cobalt transporter subunit CbtB - - - 0.0000000000005744 72.0
WH2_k127_7805739_5 Fusaric acid resistance protein-like - - - 0.0009897 48.0
WH2_k127_7806540_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.947e-275 855.0
WH2_k127_7806540_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 515.0
WH2_k127_7806540_10 Endoribonuclease L-PSP - - - 0.00000000000000000000000000008908 119.0
WH2_k127_7806540_2 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 464.0
WH2_k127_7806540_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 456.0
WH2_k127_7806540_4 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 456.0
WH2_k127_7806540_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 435.0
WH2_k127_7806540_6 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 421.0
WH2_k127_7806540_7 Transposase and inactivated K07494 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 327.0
WH2_k127_7806540_8 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000523 312.0
WH2_k127_7806540_9 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000005364 231.0
WH2_k127_7830734_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1195.0
WH2_k127_7830734_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1113.0
WH2_k127_7830734_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005095 296.0
WH2_k127_7830734_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000142 258.0
WH2_k127_7830734_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002427 242.0
WH2_k127_7830734_5 Elongation factor Tu C-terminal domain K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000295 90.0
WH2_k127_7831817_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1359.0
WH2_k127_7831817_1 FAD FMN-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 498.0
WH2_k127_7831817_10 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000006582 248.0
WH2_k127_7831817_11 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000005918 226.0
WH2_k127_7831817_12 - - - - 0.0000000000000000000000000000000008357 137.0
WH2_k127_7831817_13 - - - - 0.000000000000000000008461 99.0
WH2_k127_7831817_14 Elongation factor Tu C-terminal domain K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000006787 89.0
WH2_k127_7831817_15 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000002063 93.0
WH2_k127_7831817_16 - - - - 0.000006013 48.0
WH2_k127_7831817_17 - - - - 0.00001542 50.0
WH2_k127_7831817_18 - - - - 0.00009515 50.0
WH2_k127_7831817_19 RNA polymerase sigma K03089 - - 0.0009687 42.0
WH2_k127_7831817_2 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 418.0
WH2_k127_7831817_3 4Fe-4S dicluster domain K00184,K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 400.0
WH2_k127_7831817_4 cytosine deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 387.0
WH2_k127_7831817_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 366.0
WH2_k127_7831817_6 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 343.0
WH2_k127_7831817_7 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 342.0
WH2_k127_7831817_8 DMSO reductase anchor subunit K21309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001358 289.0
WH2_k127_7831817_9 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006006 261.0
WH2_k127_7850057_0 Histidine kinase K07648 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 427.0
WH2_k127_7850057_1 Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 361.0
WH2_k127_7850057_10 oxidoreductase K06940 - - 0.0000002099 53.0
WH2_k127_7850057_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000001551 221.0
WH2_k127_7850057_3 LysM domain K08307 - - 0.00000000000000000000000000000000000000000000001747 199.0
WH2_k127_7850057_4 Transposase K07497 - - 0.000000000000000000000000000000000000000002576 156.0
WH2_k127_7850057_5 Phosphate starvation-inducible protein, PSIF - - - 0.0000000000000000006263 89.0
WH2_k127_7850057_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000006051 79.0
WH2_k127_7850057_7 Transposase DDE domain - - - 0.00000000000003082 82.0
WH2_k127_7850057_8 - - - - 0.000000000005566 67.0
WH2_k127_7850057_9 - - - - 0.000000003423 71.0
WH2_k127_7852659_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1249.0
WH2_k127_7852659_1 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 611.0
WH2_k127_7852659_2 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 464.0
WH2_k127_7852659_3 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 309.0
WH2_k127_7852659_4 Prokaryotic cytochrome b561 K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 297.0
WH2_k127_7852659_5 Necessary for formate dehydrogenase activity K02380 - - 0.000000003353 60.0
WH2_k127_7860495_0 COG1840 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 454.0
WH2_k127_7860495_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 446.0
WH2_k127_7860495_2 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 413.0
WH2_k127_7860495_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 389.0
WH2_k127_7860495_4 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 404.0
WH2_k127_7860495_5 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000001485 225.0
WH2_k127_7860495_6 DedA family - - - 0.0000000000000000000000000000000000000000000000000000000000001532 219.0
WH2_k127_7860495_7 bond formation protein, DsbB - - - 0.0000000000000000000000000000000002846 142.0
WH2_k127_7860495_8 Protein of unknown function (DUF2794) - - - 0.00000000000000000000000000115 117.0
WH2_k127_7860495_9 bond formation protein DsbB - - - 0.00000000000000000001 99.0
WH2_k127_7887148_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.0 1092.0
WH2_k127_7887148_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 1.121e-318 989.0
WH2_k127_7887148_10 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002249 268.0
WH2_k127_7887148_11 enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000002479 240.0
WH2_k127_7887148_12 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000004302 210.0
WH2_k127_7887148_13 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000001092 207.0
WH2_k127_7887148_14 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000001379 152.0
WH2_k127_7887148_2 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01965 - 6.4.1.3 9.485e-273 855.0
WH2_k127_7887148_3 amp-dependent synthetase and ligase K01897 - 6.2.1.3 1.83e-215 680.0
WH2_k127_7887148_4 Thiolase, C-terminal domain - - - 3.123e-206 648.0
WH2_k127_7887148_5 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 583.0
WH2_k127_7887148_6 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 427.0
WH2_k127_7887148_7 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 415.0
WH2_k127_7887148_8 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 353.0
WH2_k127_7887148_9 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 316.0
WH2_k127_7924079_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000001255 185.0
WH2_k127_7959409_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 581.0
WH2_k127_7959409_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 368.0
WH2_k127_7959409_2 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 283.0
WH2_k127_7959409_3 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000006976 130.0
WH2_k127_7959409_4 helicase superfamily c-terminal domain K03732,K11927 - 3.6.4.13 0.0001616 46.0
WH2_k127_8004294_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1037.0
WH2_k127_8004294_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.984e-245 785.0
WH2_k127_8004294_10 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000826 152.0
WH2_k127_8004294_11 - - - - 0.000000000000000000000008365 106.0
WH2_k127_8004294_12 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000002636 96.0
WH2_k127_8004294_13 Response regulator receiver domain K11443 - - 0.000000000003503 66.0
WH2_k127_8004294_2 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 515.0
WH2_k127_8004294_3 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 397.0
WH2_k127_8004294_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 375.0
WH2_k127_8004294_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 329.0
WH2_k127_8004294_6 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 315.0
WH2_k127_8004294_7 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 286.0
WH2_k127_8004294_9 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000002055 170.0
WH2_k127_8069935_0 Amidohydrolase family K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 533.0
WH2_k127_8069935_1 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 516.0
WH2_k127_8069935_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 351.0
WH2_k127_8069935_11 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 337.0
WH2_k127_8069935_12 taurine ABC transporter K15551 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 354.0
WH2_k127_8069935_13 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 299.0
WH2_k127_8069935_14 ABC-type nitrate sulfonate bicarbonate transport system permease component K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 314.0
WH2_k127_8069935_15 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003385 274.0
WH2_k127_8069935_16 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002862 271.0
WH2_k127_8069935_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001187 268.0
WH2_k127_8069935_18 Thiamine monophosphate synthase - - - 0.00000000000000000000000000000000000000000000000000000000009328 211.0
WH2_k127_8069935_19 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000002441 215.0
WH2_k127_8069935_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 497.0
WH2_k127_8069935_20 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000004856 196.0
WH2_k127_8069935_21 Bacterial regulatory proteins, tetR family K18939 - - 0.0000000000000000000000000000000000000000000000000006237 190.0
WH2_k127_8069935_22 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000003829 174.0
WH2_k127_8069935_23 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000007352 171.0
WH2_k127_8069935_24 WHG domain - - - 0.00000000000000000000000000000000000000000005643 166.0
WH2_k127_8069935_25 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.00000000000000000000000002718 120.0
WH2_k127_8069935_26 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000491 104.0
WH2_k127_8069935_27 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000001545 90.0
WH2_k127_8069935_28 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.000000000000001559 80.0
WH2_k127_8069935_29 ThiS family K03154 - - 0.000000003385 67.0
WH2_k127_8069935_3 3-hydroxyacyl-coa dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 454.0
WH2_k127_8069935_4 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 415.0
WH2_k127_8069935_5 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 394.0
WH2_k127_8069935_6 dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 392.0
WH2_k127_8069935_7 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 391.0
WH2_k127_8069935_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 368.0
WH2_k127_8069935_9 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 361.0
WH2_k127_8122666_0 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 506.0
WH2_k127_8122666_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 441.0
WH2_k127_8122666_10 Protein conserved in bacteria K09780 - - 0.000000000000000000000000001136 124.0
WH2_k127_8122666_2 gntR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 420.0
WH2_k127_8122666_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 349.0
WH2_k127_8122666_4 Glycosyl transferase WecB/TagA/CpsF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 334.0
WH2_k127_8122666_5 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K01872,K07050 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 328.0
WH2_k127_8122666_6 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 296.0
WH2_k127_8122666_7 Transcriptional regulator, AraC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
WH2_k127_8122666_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000192 275.0
WH2_k127_8122666_9 Polysaccharide biosynthesis/export protein - - - 0.000000000000000000000000000000000000000000000000005027 184.0
WH2_k127_8133838_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 3.873e-249 799.0
WH2_k127_8133838_1 PFAM AMP-dependent synthetase and ligase K18661 - - 9.154e-229 718.0
WH2_k127_8133838_10 COG1126 ABC-type polar amino acid transport system, ATPase component K02028,K02029,K09972,K10038 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 346.0
WH2_k127_8133838_11 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 307.0
WH2_k127_8133838_12 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 299.0
WH2_k127_8133838_13 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000001717 244.0
WH2_k127_8133838_14 Belongs to the UPF0310 family - - - 0.00000000000000000000000000000000000000000000000000000000009801 215.0
WH2_k127_8133838_15 Required for resistance to the phenazine antibiotic - - - 0.000000000000000000000000000000000000000000000000000193 190.0
WH2_k127_8133838_16 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000002049 168.0
WH2_k127_8133838_17 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000007437 126.0
WH2_k127_8133838_18 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000004059 115.0
WH2_k127_8133838_19 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000002741 71.0
WH2_k127_8133838_2 Sugar (and other) transporter - - - 7.391e-221 691.0
WH2_k127_8133838_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 559.0
WH2_k127_8133838_4 amino acid transport K09969 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 469.0
WH2_k127_8133838_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 461.0
WH2_k127_8133838_6 amino acid ABC transporter K09970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 411.0
WH2_k127_8133838_7 amino acid ABC transporter K02029,K09971,K10002,K10037 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 406.0
WH2_k127_8133838_8 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 334.0
WH2_k127_8133838_9 PFAM BFD domain protein 2Fe-2S -binding domain protein K10815 - 1.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 346.0
WH2_k127_8136659_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 2.084e-318 987.0
WH2_k127_8136659_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K14446 - 1.3.1.85 1.206e-248 773.0
WH2_k127_8136659_10 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 539.0
WH2_k127_8136659_11 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 529.0
WH2_k127_8136659_12 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 512.0
WH2_k127_8136659_13 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 508.0
WH2_k127_8136659_14 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 479.0
WH2_k127_8136659_15 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 478.0
WH2_k127_8136659_16 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 422.0
WH2_k127_8136659_17 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 433.0
WH2_k127_8136659_18 Extracellular liganD-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 396.0
WH2_k127_8136659_19 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 404.0
WH2_k127_8136659_2 E1-E2 ATPase K01534 - 3.6.3.3,3.6.3.5 3.48e-247 782.0
WH2_k127_8136659_20 abc transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 394.0
WH2_k127_8136659_21 Amidohydrolase K10220 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 349.0
WH2_k127_8136659_22 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 340.0
WH2_k127_8136659_23 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 345.0
WH2_k127_8136659_24 helix_turn_helix isocitrate lyase regulation K13641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 322.0
WH2_k127_8136659_25 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 295.0
WH2_k127_8136659_26 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004614 301.0
WH2_k127_8136659_27 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009732 286.0
WH2_k127_8136659_28 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001027 271.0
WH2_k127_8136659_29 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007653 272.0
WH2_k127_8136659_3 COG1960 Acyl-CoA dehydrogenases K14448 - 1.3.8.12 2.716e-231 728.0
WH2_k127_8136659_30 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003539 272.0
WH2_k127_8136659_31 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005367 261.0
WH2_k127_8136659_32 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000001286 252.0
WH2_k127_8136659_33 PFAM Dimethylmenaquinone methyltransferase K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000000000000000009195 239.0
WH2_k127_8136659_34 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000001242 237.0
WH2_k127_8136659_35 Protein of unknown function (DUF429) - - - 0.00000000000000000000000000000000000000000000000000000000000002254 234.0
WH2_k127_8136659_36 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000001022 216.0
WH2_k127_8136659_37 - - - - 0.000000000000000000000000000000000000000000000000002194 188.0
WH2_k127_8136659_38 helix_turn_helix, mercury resistance K13639 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000004759 185.0
WH2_k127_8136659_39 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000003263 169.0
WH2_k127_8136659_4 FAD binding domain K00104,K05797 - 1.1.3.15,1.17.99.1 3.144e-217 696.0
WH2_k127_8136659_40 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000001327 159.0
WH2_k127_8136659_41 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000005674 168.0
WH2_k127_8136659_42 AraC-binding-like domain - - - 0.000000000000000000000000000000000000001438 160.0
WH2_k127_8136659_43 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000002813 117.0
WH2_k127_8136659_44 - - - - 0.00000000000000000000000002411 116.0
WH2_k127_8136659_45 transcriptional - - - 0.0000000000000000000000008172 109.0
WH2_k127_8136659_46 transcriptional - - - 0.00000000000000000005874 96.0
WH2_k127_8136659_47 Phospholipase_D-nuclease N-terminal - - - 0.0000000000000000007161 87.0
WH2_k127_8136659_48 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000001388 71.0
WH2_k127_8136659_5 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.615e-210 668.0
WH2_k127_8136659_50 PFAM Hypoxia induced protein conserved region - - - 0.00000000002801 65.0
WH2_k127_8136659_51 - - - - 0.000003566 55.0
WH2_k127_8136659_6 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 5.478e-199 632.0
WH2_k127_8136659_7 Rieske (2Fe-2S) domain-containing protein K15060 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 614.0
WH2_k127_8136659_8 Cupin domain K00450 - 1.13.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 546.0
WH2_k127_8136659_9 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 534.0
WH2_k127_8175411_0 FAD linked oxidases, C-terminal domain K00102 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 567.0
WH2_k127_8175411_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 368.0
WH2_k127_8175411_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 366.0
WH2_k127_8175411_3 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 349.0
WH2_k127_8175411_4 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000757 87.0
WH2_k127_8194357_0 synthetase K01907 - 6.2.1.16 3.072e-272 852.0
WH2_k127_8194357_1 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 2.698e-269 839.0
WH2_k127_8194357_10 Belongs to the DapA family K01707 - 4.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 411.0
WH2_k127_8194357_11 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 411.0
WH2_k127_8194357_12 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 387.0
WH2_k127_8194357_13 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 381.0
WH2_k127_8194357_14 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 390.0
WH2_k127_8194357_15 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 378.0
WH2_k127_8194357_16 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 359.0
WH2_k127_8194357_17 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 359.0
WH2_k127_8194357_18 Proteasome-type protease K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 362.0
WH2_k127_8194357_19 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 341.0
WH2_k127_8194357_2 A circularly permuted ATPgrasp - - - 1.458e-214 675.0
WH2_k127_8194357_20 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 335.0
WH2_k127_8194357_21 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008804 323.0
WH2_k127_8194357_22 Dihydrodipicolinate synthetase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 319.0
WH2_k127_8194357_23 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 331.0
WH2_k127_8194357_24 3-beta hydroxysteroid dehydrogenase/isomerase family K18981 - 1.1.1.203 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 329.0
WH2_k127_8194357_25 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 317.0
WH2_k127_8194357_26 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004927 278.0
WH2_k127_8194357_27 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001207 282.0
WH2_k127_8194357_28 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006023 265.0
WH2_k127_8194357_29 GntR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007767 252.0
WH2_k127_8194357_3 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 5.675e-207 650.0
WH2_k127_8194357_30 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006164 244.0
WH2_k127_8194357_31 ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000123 255.0
WH2_k127_8194357_32 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000645 237.0
WH2_k127_8194357_33 helix_turn_helix, arabinose operon control protein K18954 - - 0.0000000000000000000000000000000000000000000000000000000001562 214.0
WH2_k127_8194357_34 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000187 198.0
WH2_k127_8194357_35 PFAM Nickel transport complex, NikM subunit, transmembrane - - - 0.00000000000000000000000000000000000000000000000005189 185.0
WH2_k127_8194357_36 Belongs to the globin family - - - 0.00000000000000000000000000000000000000000002927 166.0
WH2_k127_8194357_37 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000006408 124.0
WH2_k127_8194357_38 amino acid K02030 - - 0.000000000000000000000000004721 120.0
WH2_k127_8194357_4 peptidase dimerisation domain protein - - - 1.221e-199 655.0
WH2_k127_8194357_40 subunits C and D K02049,K15578 - - 0.000000004107 57.0
WH2_k127_8194357_41 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.0004547 51.0
WH2_k127_8194357_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 619.0
WH2_k127_8194357_6 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 582.0
WH2_k127_8194357_7 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 452.0
WH2_k127_8194357_8 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K21395 GO:0003674,GO:0005488,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0030246,GO:0033554,GO:0034219,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 437.0
WH2_k127_8194357_9 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 417.0
WH2_k127_8195058_0 ABC transporter K02027 - - 7.319e-215 673.0
WH2_k127_8195058_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 514.0
WH2_k127_8195058_10 LysR substrate binding domain K11921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 357.0
WH2_k127_8195058_11 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 343.0
WH2_k127_8195058_12 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002405 277.0
WH2_k127_8195058_13 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 272.0
WH2_k127_8195058_14 Tyrosine phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000003867 272.0
WH2_k127_8195058_15 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000153 250.0
WH2_k127_8195058_16 AzlC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006237 248.0
WH2_k127_8195058_17 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000001772 251.0
WH2_k127_8195058_18 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000003619 211.0
WH2_k127_8195058_19 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001502 204.0
WH2_k127_8195058_2 ABC-type sugar transport systems permease components K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 489.0
WH2_k127_8195058_20 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000007738 203.0
WH2_k127_8195058_21 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000005778 171.0
WH2_k127_8195058_22 Cupin domain - - - 0.0000000000000000000000000000000000002804 144.0
WH2_k127_8195058_23 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000000000003123 103.0
WH2_k127_8195058_24 DNA polymerase K02337 - 2.7.7.7 0.0000006251 57.0
WH2_k127_8195058_3 Belongs to the ABC transporter superfamily K05816 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 471.0
WH2_k127_8195058_4 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 451.0
WH2_k127_8195058_5 ABC-type sugar transport system, permease component K02026,K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 449.0
WH2_k127_8195058_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 447.0
WH2_k127_8195058_7 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 406.0
WH2_k127_8195058_8 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 394.0
WH2_k127_8195058_9 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 394.0
WH2_k127_8198013_0 Protein export membrane protein K03296,K18138 - - 0.0 1243.0
WH2_k127_8198013_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 603.0
WH2_k127_8198013_10 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001846 261.0
WH2_k127_8198013_11 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000435 175.0
WH2_k127_8198013_12 Belongs to the peptidase S1 family K01310,K09615,K09628 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.1 0.000000000000000000000000000000000000000000000006446 191.0
WH2_k127_8198013_13 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000009327 172.0
WH2_k127_8198013_14 Predicted membrane protein (DUF2142) - - - 0.00000000000000000000001048 117.0
WH2_k127_8198013_15 PFAM GtrA family protein - - - 0.00000000000000000000002687 104.0
WH2_k127_8198013_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000001998 104.0
WH2_k127_8198013_17 chemotaxis protein K03406 - - 0.00000000003299 71.0
WH2_k127_8198013_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 464.0
WH2_k127_8198013_3 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 434.0
WH2_k127_8198013_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 376.0
WH2_k127_8198013_5 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 339.0
WH2_k127_8198013_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 325.0
WH2_k127_8198013_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 323.0
WH2_k127_8198013_8 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 329.0
WH2_k127_8198013_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000008416 251.0
WH2_k127_8246799_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 4.437e-308 951.0
WH2_k127_8246799_1 Sulfite reductase K00381 - 1.8.1.2 1.035e-246 775.0
WH2_k127_8246799_10 ATPases associated with a variety of cellular activities K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 327.0
WH2_k127_8246799_11 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 295.0
WH2_k127_8246799_12 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000004782 262.0
WH2_k127_8246799_13 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 266.0
WH2_k127_8246799_14 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005853 239.0
WH2_k127_8246799_15 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000000000000000000000000000003065 227.0
WH2_k127_8246799_16 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000007202 186.0
WH2_k127_8246799_17 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000000000000000000002588 194.0
WH2_k127_8246799_18 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000003986 179.0
WH2_k127_8246799_19 Urease beta subunit K01429 - 3.5.1.5 0.00000000000000000000000000000000000000000000002629 174.0
WH2_k127_8246799_2 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 4.855e-197 632.0
WH2_k127_8246799_20 Haem-degrading K11477 - - 0.0000000000000000000000000000000000000005416 155.0
WH2_k127_8246799_21 Bacterial protein of unknown function (DUF934) - - - 0.0000000000000000000000000000000007121 142.0
WH2_k127_8246799_22 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - - 0.0000000000000363 75.0
WH2_k127_8246799_3 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 422.0
WH2_k127_8246799_4 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 422.0
WH2_k127_8246799_5 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 421.0
WH2_k127_8246799_6 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 412.0
WH2_k127_8246799_7 ABC transporter K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 361.0
WH2_k127_8246799_8 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 361.0
WH2_k127_8246799_9 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 360.0
WH2_k127_8256706_0 TonB dependent receptor K02014 - - 1.828e-206 675.0
WH2_k127_8256706_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 572.0
WH2_k127_8256706_10 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 382.0
WH2_k127_8256706_11 PFAM Glutathione S-transferase domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008876 281.0
WH2_k127_8256706_12 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001135 250.0
WH2_k127_8256706_13 FecR protein K07165 - - 0.000000000000000000000000000000000000000000000000000000000000006379 229.0
WH2_k127_8256706_14 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000232 203.0
WH2_k127_8256706_15 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000001602 189.0
WH2_k127_8256706_16 transcriptional regulator K06075 - - 0.0000000000000000000000000000000000000000000000009812 178.0
WH2_k127_8256706_17 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000006363 173.0
WH2_k127_8256706_18 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000009888 181.0
WH2_k127_8256706_19 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000005001 111.0
WH2_k127_8256706_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 516.0
WH2_k127_8256706_20 Protein of unknown function (DUF3325) - - - 0.0000000000000005403 91.0
WH2_k127_8256706_22 PAS domain - - - 0.00000000000003183 79.0
WH2_k127_8256706_24 - - - - 0.00000006042 63.0
WH2_k127_8256706_25 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0007619 44.0
WH2_k127_8256706_3 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 514.0
WH2_k127_8256706_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 518.0
WH2_k127_8256706_5 Fusaric acid resistance protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 521.0
WH2_k127_8256706_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 464.0
WH2_k127_8256706_7 PFAM aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 455.0
WH2_k127_8256706_8 Oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 452.0
WH2_k127_8256706_9 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 456.0
WH2_k127_8277422_0 Aminotransferase class-III K15372 - 2.6.1.55 9.098e-215 691.0
WH2_k127_8277422_1 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 489.0
WH2_k127_8277422_2 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K07536 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 401.0
WH2_k127_8277422_3 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001781 292.0
WH2_k127_8277422_4 response regulator K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003446 267.0
WH2_k127_8277422_5 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000003382 76.0
WH2_k127_829947_0 Cation transporter/ATPase, N-terminus K01531,K01537 - 3.6.3.2,3.6.3.8 0.0 1158.0
WH2_k127_829947_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 471.0
WH2_k127_829947_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 437.0
WH2_k127_829947_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 433.0
WH2_k127_829947_4 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 400.0
WH2_k127_829947_5 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 396.0
WH2_k127_829947_6 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 382.0
WH2_k127_829947_7 Biotin carboxylase C-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006672 291.0
WH2_k127_829947_8 LysR substrate binding domain K03566,K17850 - - 0.0000000000000000000000000000000000000000000000000000002045 201.0
WH2_k127_829947_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA - - - 0.000000000000000000000001486 104.0
WH2_k127_831928_0 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000003029 245.0
WH2_k127_831928_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000003497 209.0
WH2_k127_831928_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000002676 208.0
WH2_k127_831928_3 endopeptidase activity - - - 0.000000000007684 78.0
WH2_k127_8329166_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.072e-212 668.0
WH2_k127_8329166_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 445.0
WH2_k127_8329166_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002624 221.0
WH2_k127_8329166_11 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000004826 215.0
WH2_k127_8329166_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001193 208.0
WH2_k127_8329166_13 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000005614 194.0
WH2_k127_8329166_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000832 192.0
WH2_k127_8329166_15 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000007533 184.0
WH2_k127_8329166_16 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000008488 182.0
WH2_k127_8329166_17 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000003432 173.0
WH2_k127_8329166_18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000001152 173.0
WH2_k127_8329166_19 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000004393 157.0
WH2_k127_8329166_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 396.0
WH2_k127_8329166_20 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000006578 140.0
WH2_k127_8329166_21 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000001883 135.0
WH2_k127_8329166_22 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000002695 124.0
WH2_k127_8329166_23 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000003645 91.0
WH2_k127_8329166_24 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001941 78.0
WH2_k127_8329166_25 Ribosomal protein L30 K02907 - - 0.00000000000244 76.0
WH2_k127_8329166_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 351.0
WH2_k127_8329166_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 319.0
WH2_k127_8329166_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 285.0
WH2_k127_8329166_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 282.0
WH2_k127_8329166_7 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001271 259.0
WH2_k127_8329166_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005289 250.0
WH2_k127_8329166_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000007131 235.0
WH2_k127_8344658_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 495.0
WH2_k127_8344658_1 PFAM chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 428.0
WH2_k127_8344658_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 383.0
WH2_k127_8344658_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 348.0
WH2_k127_8344658_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001349 295.0
WH2_k127_8344658_5 - - - - 0.0000000000000000000000000000000000000000000001811 187.0
WH2_k127_8344658_6 PFAM Auxin Efflux Carrier K07088 - - 0.00000000000002518 75.0
WH2_k127_8367079_0 Belongs to the GPI family K01810 - 5.3.1.9 1.779e-219 692.0
WH2_k127_8367079_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 598.0
WH2_k127_8367079_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000001593 209.0
WH2_k127_8367079_11 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000009901 188.0
WH2_k127_8367079_12 - - - - 0.000000000000000000000000000000000000000000005085 177.0
WH2_k127_8367079_13 NUDIX domain - - - 0.00000000000000000000000000000000000001253 151.0
WH2_k127_8367079_14 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000001 138.0
WH2_k127_8367079_15 COG1530 Ribonucleases G and E K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000002043 147.0
WH2_k127_8367079_16 Protein of unknown function (DUF2948) - - - 0.00000000000000000000000004308 113.0
WH2_k127_8367079_17 Belongs to the ABC transporter superfamily K02031 - - 0.0000151 51.0
WH2_k127_8367079_18 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00005964 49.0
WH2_k127_8367079_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 584.0
WH2_k127_8367079_3 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 438.0
WH2_k127_8367079_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 332.0
WH2_k127_8367079_5 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 341.0
WH2_k127_8367079_6 Uncharacterised protein family (UPF0262) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009256 233.0
WH2_k127_8367079_7 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000000000003413 229.0
WH2_k127_8367079_8 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000008121 230.0
WH2_k127_8367079_9 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000826 244.0
WH2_k127_8382142_0 Putative Na+/H+ antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 608.0
WH2_k127_8382142_1 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 598.0
WH2_k127_8382142_2 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 522.0
WH2_k127_8382142_3 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00380 - 1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 413.0
WH2_k127_8382142_4 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 384.0
WH2_k127_8382142_5 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 383.0
WH2_k127_8382142_6 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 375.0
WH2_k127_8382142_7 Tat pathway signal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001212 233.0
WH2_k127_8382142_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000007798 214.0
WH2_k127_8382142_9 Peptidase propeptide and YPEB domain - - - 0.000000000000000000000000000000005286 134.0
WH2_k127_8400068_0 Glucose inhibited division protein A - - - 2.609e-249 775.0
WH2_k127_8400068_1 monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 617.0
WH2_k127_8400068_10 monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 417.0
WH2_k127_8400068_11 monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 415.0
WH2_k127_8400068_12 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 385.0
WH2_k127_8400068_13 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 368.0
WH2_k127_8400068_14 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 364.0
WH2_k127_8400068_15 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 339.0
WH2_k127_8400068_16 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04098 - 1.13.11.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 331.0
WH2_k127_8400068_17 PFAM SMP-30 Gluconolaconase LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 333.0
WH2_k127_8400068_18 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 321.0
WH2_k127_8400068_19 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 323.0
WH2_k127_8400068_2 Binding-protein-dependent transport system inner membrane component K15554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 591.0
WH2_k127_8400068_20 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 328.0
WH2_k127_8400068_21 TOBE domain K02052,K11080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 314.0
WH2_k127_8400068_22 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 316.0
WH2_k127_8400068_23 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 304.0
WH2_k127_8400068_24 (ABC) transporter K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 321.0
WH2_k127_8400068_25 Bacterial transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 294.0
WH2_k127_8400068_26 ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 293.0
WH2_k127_8400068_27 alpha/beta hydrolase fold K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006964 287.0
WH2_k127_8400068_28 LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002009 275.0
WH2_k127_8400068_29 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002753 264.0
WH2_k127_8400068_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 559.0
WH2_k127_8400068_30 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001314 257.0
WH2_k127_8400068_31 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000003353 239.0
WH2_k127_8400068_32 - - - - 0.00000000000000000000000000000000000000000000000000000002176 204.0
WH2_k127_8400068_33 Belongs to the peptidase S33 family - - - 0.0000000000000000000000000000000000000000000000000000003553 213.0
WH2_k127_8400068_34 N-terminal TM domain of oligopeptide transport permease C - - - 0.00000000000000000000000000000000000000000000001467 187.0
WH2_k127_8400068_35 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000002135 163.0
WH2_k127_8400068_4 FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family K20938 - 1.14.14.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 541.0
WH2_k127_8400068_5 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 527.0
WH2_k127_8400068_6 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 466.0
WH2_k127_8400068_7 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 460.0
WH2_k127_8400068_8 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 439.0
WH2_k127_8400068_9 NMT1/THI5 like K15553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 438.0
WH2_k127_8476954_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 434.0
WH2_k127_8476954_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 396.0
WH2_k127_8476954_2 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008349 307.0
WH2_k127_8476954_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000004263 181.0
WH2_k127_8476954_4 Polysaccharide biosynthesis protein K03328 - - 0.0000000000009786 81.0
WH2_k127_8476954_5 protein methyltransferase activity - - - 0.000003165 58.0
WH2_k127_8511046_0 COG1138 Cytochrome c biogenesis factor K02198 - - 2.439e-280 883.0
WH2_k127_8511046_1 Sugar (and other) transporter K03762 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 447.0
WH2_k127_8511046_10 Protein of unknown function (DUF1275) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007372 235.0
WH2_k127_8511046_11 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000009817 224.0
WH2_k127_8511046_12 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000005919 207.0
WH2_k127_8511046_13 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000002166 197.0
WH2_k127_8511046_14 AhpC/TSA family K02199 - - 0.000000000000000000000000000000000000000000000000000008438 201.0
WH2_k127_8511046_15 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000005041 201.0
WH2_k127_8511046_16 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000238 162.0
WH2_k127_8511046_17 Cytochrome C biogenesis protein K02200 - - 0.00000000000000000000000000000000000003036 156.0
WH2_k127_8511046_18 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000002245 57.0
WH2_k127_8511046_2 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 436.0
WH2_k127_8511046_3 Sugar (and other) transporter K03762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 427.0
WH2_k127_8511046_4 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 421.0
WH2_k127_8511046_5 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 370.0
WH2_k127_8511046_6 Histidine kinase K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 348.0
WH2_k127_8511046_7 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 332.0
WH2_k127_8511046_8 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000005838 263.0
WH2_k127_8511046_9 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002375 269.0
WH2_k127_8548868_0 DNA polymerase K02337 - 2.7.7.7 0.0 1092.0
WH2_k127_8548868_1 Receptor family ligand binding region K01999 - - 2.214e-198 625.0
WH2_k127_8548868_2 Histidine kinase K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 626.0
WH2_k127_8548868_3 Glycosyl hydrolases family 15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 432.0
WH2_k127_8548868_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 285.0
WH2_k127_8548868_5 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000007527 137.0
WH2_k127_8548868_6 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000006729 142.0
WH2_k127_8548868_7 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000002146 97.0
WH2_k127_8548868_8 STAS domain K04749 - - 0.000000000000001137 81.0
WH2_k127_8615506_0 glutamine synthetase K01915 - 6.3.1.2 2.69e-238 751.0
WH2_k127_8615506_1 Aspartate tyrosine aromatic aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 550.0
WH2_k127_8615506_2 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001622 281.0
WH2_k127_8615506_3 Glycosyl transferase family, a/b domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005271 263.0
WH2_k127_8615506_4 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000001087 204.0
WH2_k127_8615506_5 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0000000000000000000000000000000000000000000001752 179.0
WH2_k127_8615506_6 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000004635 140.0
WH2_k127_8615506_7 OmpA family - - - 0.00000003319 61.0
WH2_k127_8615506_8 - - - - 0.0000009867 61.0
WH2_k127_8615861_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 6.559e-257 807.0
WH2_k127_8615861_1 Sodium proton antiporter K03316 - - 2.023e-194 619.0
WH2_k127_8615861_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 301.0
WH2_k127_8615861_3 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000002489 210.0
WH2_k127_8615861_4 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000002513 191.0
WH2_k127_8615861_5 serine-type endopeptidase activity K20276 - - 0.000000000000000000000000000000000000000000000000194 195.0
WH2_k127_8615861_6 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000002478 147.0
WH2_k127_8615861_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000686 66.0
WH2_k127_8638718_0 ABC transporter C-terminal domain K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 1.041e-231 726.0
WH2_k127_8638718_1 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 401.0
WH2_k127_8638718_2 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 346.0
WH2_k127_8638718_3 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K02049 - - 0.0000000000000000000000000000000000000000000000000000000000004676 230.0
WH2_k127_8638718_4 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000002468 171.0
WH2_k127_8638718_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000107 169.0
WH2_k127_8638718_6 Ring hydroxylating subunit beta family protein 1 - - - 0.000000000000000000000000000000009313 134.0
WH2_k127_8638718_7 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000001628 91.0
WH2_k127_8643916_0 Binding-protein-dependent transport system inner membrane component K02011 - - 5.349e-222 699.0
WH2_k127_8643916_1 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 483.0
WH2_k127_8643916_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 426.0
WH2_k127_8643916_3 Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 440.0
WH2_k127_8643916_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000003137 145.0
WH2_k127_8673488_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 1.312e-309 983.0
WH2_k127_8673488_1 Acetyl-CoA dehydrogenase C-terminal like K00248,K00249 - 1.3.8.1,1.3.8.7 2.078e-261 817.0
WH2_k127_8673488_10 Protein tyrosine serine phosphatase K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000001087 225.0
WH2_k127_8673488_11 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000000000000000000000000000000000002098 209.0
WH2_k127_8673488_12 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000007784 199.0
WH2_k127_8673488_13 membrane - - - 0.00000000000000000000000000000000000000004888 154.0
WH2_k127_8673488_14 Peptidase family M23 - - - 0.000000000000000000000000000000000000002363 164.0
WH2_k127_8673488_15 Transcriptional regulator - - - 0.0000000000000000000000000000000000001451 147.0
WH2_k127_8673488_16 diguanylate cyclase - - - 0.000000000000000000000000000000002398 143.0
WH2_k127_8673488_17 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000001617 55.0
WH2_k127_8673488_2 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 494.0
WH2_k127_8673488_3 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 492.0
WH2_k127_8673488_4 ATP-dependent helicase K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 449.0
WH2_k127_8673488_5 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 385.0
WH2_k127_8673488_6 Binding-protein-dependent transport system inner membrane component K02026,K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 366.0
WH2_k127_8673488_7 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 357.0
WH2_k127_8673488_8 ABC transporter K05816,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 349.0
WH2_k127_8673488_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000001596 229.0
WH2_k127_8686809_0 Fumarase C-terminus K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 1.545e-266 829.0
WH2_k127_8686809_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038,K21977 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 542.0
WH2_k127_8686809_10 Transcriptional regulatory protein, C terminal K07666 - - 0.0000000000000000000000000000000000000000000000000000001885 201.0
WH2_k127_8686809_11 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000001646 181.0
WH2_k127_8686809_12 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000002069 179.0
WH2_k127_8686809_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000001322 166.0
WH2_k127_8686809_14 Stringent starvation protein B K09985 - - 0.000000000000000000000000000000000000000003658 161.0
WH2_k127_8686809_15 Cysteine synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000005323 134.0
WH2_k127_8686809_16 Rieske 2Fe-2S - - - 0.000000000000000000000000000129 128.0
WH2_k127_8686809_17 Histidine Phosphotransfer domain - - - 0.0000000000000000000001949 107.0
WH2_k127_8686809_18 phosphorelay signal transduction system K03413,K07720 - - 0.00000000000000000002214 98.0
WH2_k127_8686809_19 PAS domain - - - 0.00000000000000000005769 97.0
WH2_k127_8686809_2 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 547.0
WH2_k127_8686809_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 448.0
WH2_k127_8686809_4 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 397.0
WH2_k127_8686809_5 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 355.0
WH2_k127_8686809_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 309.0
WH2_k127_8686809_7 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002264 239.0
WH2_k127_8686809_8 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000002962 213.0
WH2_k127_8686809_9 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000001331 206.0
WH2_k127_868756_0 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 3.09e-243 758.0
WH2_k127_868756_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 558.0
WH2_k127_868756_2 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 534.0
WH2_k127_868756_3 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003154 243.0
WH2_k127_868756_4 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000001464 171.0
WH2_k127_868756_5 - - - - 0.00000000000000002221 87.0
WH2_k127_8735807_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 4.335e-241 752.0
WH2_k127_8735807_1 Binding-protein-dependent transport system inner membrane component K02050 - - 2.649e-237 746.0
WH2_k127_8735807_10 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 294.0
WH2_k127_8735807_11 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001326 266.0
WH2_k127_8735807_12 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001947 245.0
WH2_k127_8735807_13 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009931 242.0
WH2_k127_8735807_14 diguanylate cyclase - - - 0.0000000000000000000000000000000000000003633 164.0
WH2_k127_8735807_15 - - - - 0.00000000000000000000000000000000001334 154.0
WH2_k127_8735807_16 PA14 domain - - - 0.000000000000006113 83.0
WH2_k127_8735807_2 PAS PAC domain-containing protein - - - 5.573e-197 636.0
WH2_k127_8735807_3 C-terminal AAA-associated domain K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 575.0
WH2_k127_8735807_4 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 473.0
WH2_k127_8735807_5 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 414.0
WH2_k127_8735807_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 398.0
WH2_k127_8735807_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 344.0
WH2_k127_8735807_8 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 306.0
WH2_k127_8735807_9 CYTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 313.0
WH2_k127_8808085_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 2.638e-278 874.0
WH2_k127_8808085_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 600.0
WH2_k127_8808085_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 508.0
WH2_k127_8808085_3 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 301.0
WH2_k127_8808085_4 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000002126 183.0
WH2_k127_8808085_5 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000001846 181.0
WH2_k127_8808085_6 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000009725 114.0
WH2_k127_8828865_0 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00380 - 1.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 460.0
WH2_k127_8828865_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 359.0
WH2_k127_8828865_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K00380,K03734 - 1.8.1.2,2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 363.0
WH2_k127_8828865_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 310.0
WH2_k127_8828865_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000002374 86.0
WH2_k127_8933997_0 Cache domain - - - 1.126e-298 938.0
WH2_k127_8933997_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.973e-249 779.0
WH2_k127_8933997_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000002255 212.0
WH2_k127_8933997_11 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000007813 207.0
WH2_k127_8933997_12 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000002517 197.0
WH2_k127_8933997_13 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000005784 174.0
WH2_k127_8933997_14 spore germination - - - 0.00000000000000000000000000000000000000000005174 176.0
WH2_k127_8933997_15 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000152 164.0
WH2_k127_8933997_16 Major Facilitator Superfamily - - - 0.00000000000000000000000000000001056 135.0
WH2_k127_8933997_17 Protein of unknown function (DUF721) - - - 0.000000000000000000000000000105 121.0
WH2_k127_8933997_18 Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding - - - 0.0000000000000000000000116 108.0
WH2_k127_8933997_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 574.0
WH2_k127_8933997_3 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 549.0
WH2_k127_8933997_4 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 468.0
WH2_k127_8933997_5 COG1194 A G-specific DNA glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 445.0
WH2_k127_8933997_6 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 430.0
WH2_k127_8933997_7 PFAM Enoyl-CoA hydratase isomerase K18383 - 4.1.2.41,4.2.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 296.0
WH2_k127_8933997_8 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000008711 239.0
WH2_k127_8933997_9 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000007594 219.0
WH2_k127_8935873_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 524.0
WH2_k127_8935873_1 tRNA synthetases class II core domain (F) K01880 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 377.0
WH2_k127_8935873_10 Domain of unknown function (DUF1127) - - - 0.0000006938 56.0
WH2_k127_8935873_11 TIGRFAM protein TolA - - - 0.000005261 52.0
WH2_k127_8935873_2 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 351.0
WH2_k127_8935873_3 COG0811 Biopolymer transport proteins K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 322.0
WH2_k127_8935873_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000006917 220.0
WH2_k127_8935873_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000002896 220.0
WH2_k127_8935873_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000004826 197.0
WH2_k127_8935873_7 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000000000000000000000000000000003633 176.0
WH2_k127_8935873_8 NUDIX domain - - - 0.0000000000000000000000000000000000000000000008523 186.0
WH2_k127_8935873_9 thioesterase K07107 - - 0.0000000000000000000000000000000000002213 146.0
WH2_k127_8945229_0 Psort location Cytoplasmic, score 7.50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 586.0
WH2_k127_8945229_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 356.0
WH2_k127_8945229_2 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 290.0
WH2_k127_8945229_3 Protein of unknown function (DUF1194) - - - 0.000000000000000000000000000000000000000000000000000000000000001134 225.0
WH2_k127_8945229_4 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000002114 106.0
WH2_k127_8945229_5 Uncharacterized BCR, YaiI/YqxD family COG1671 K09768 - - 0.000000000000000000008899 95.0
WH2_k127_8986637_0 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 421.0
WH2_k127_8986637_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 374.0
WH2_k127_8986637_10 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000002116 164.0
WH2_k127_8986637_11 - - - - 0.000000000000000000000000000000000002035 147.0
WH2_k127_8986637_12 PAS domain - - - 0.000000000000000000004121 98.0
WH2_k127_8986637_13 Subtilase family - - - 0.0000003605 63.0
WH2_k127_8986637_2 COG0859 ADP-heptose LPS heptosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 352.0
WH2_k127_8986637_3 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 333.0
WH2_k127_8986637_4 Glycosyl hydrolases family 8 K20542 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 329.0
WH2_k127_8986637_5 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 310.0
WH2_k127_8986637_6 Alpha beta hydrolase K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 289.0
WH2_k127_8986637_7 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001003 284.0
WH2_k127_8986637_8 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000005347 199.0
WH2_k127_8986637_9 transporter K08978 - - 0.000000000000000000000000000000000000000000000000000001722 195.0
WH2_k127_8993455_0 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 550.0
WH2_k127_8993455_1 PFAM FAD binding domain of DNA photolyase K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 549.0
WH2_k127_8993455_10 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 363.0
WH2_k127_8993455_11 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 368.0
WH2_k127_8993455_12 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 345.0
WH2_k127_8993455_13 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 300.0
WH2_k127_8993455_14 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008168 259.0
WH2_k127_8993455_15 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002452 248.0
WH2_k127_8993455_16 helix-turn-helix- domain containing protein, AraC type K13653 - - 0.000000000000000000000000000000000000000000000000000000000000000002579 250.0
WH2_k127_8993455_17 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000002468 233.0
WH2_k127_8993455_18 -acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000009255 212.0
WH2_k127_8993455_19 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000001813 189.0
WH2_k127_8993455_2 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 500.0
WH2_k127_8993455_20 bleomycin resistance protein K06996 - - 0.0000000000000000000000000000000000000000001316 169.0
WH2_k127_8993455_22 PspC domain K03973 - - 0.00000000000000000000000000001839 121.0
WH2_k127_8993455_23 transcriptional - - - 0.00000000000000000000000000004098 121.0
WH2_k127_8993455_24 Protein of unknown function (DUF535) K09824 - - 0.00000000000000000000000000005077 128.0
WH2_k127_8993455_25 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000000000000000002222 114.0
WH2_k127_8993455_26 Peptidase S24-like - - - 0.00000000000000007266 89.0
WH2_k127_8993455_27 Phage shock protein B K03970 - - 0.00000000000000015 82.0
WH2_k127_8993455_28 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000002734 83.0
WH2_k127_8993455_29 response regulator - - - 0.0000000000001791 78.0
WH2_k127_8993455_3 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 489.0
WH2_k127_8993455_30 PFAM Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.0002845 44.0
WH2_k127_8993455_31 Belongs to the flagella basal body rod proteins family K02388 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.0006993 48.0
WH2_k127_8993455_4 COG4597 ABC-type amino acid transport system, permease component K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 468.0
WH2_k127_8993455_5 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 462.0
WH2_k127_8993455_6 ATPases associated with a variety of cellular activities K02028,K09972 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 425.0
WH2_k127_8993455_7 Sigma-54 interaction domain K03974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 408.0
WH2_k127_8993455_8 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 406.0
WH2_k127_8993455_9 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 381.0
WH2_k127_9009180_0 Di-haem oxidoreductase, putative peroxidase - - - 4.428e-194 616.0
WH2_k127_9009180_1 Imelysin K07231 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 533.0
WH2_k127_9009180_2 impB/mucB/samB family K14161 - - 0.000000000000000000000000000000000003466 142.0
WH2_k127_9009180_3 - - - - 0.00000000000000000000000000006383 118.0
WH2_k127_9009180_4 SOS response K14160 - - 0.000000000000000000000001139 113.0
WH2_k127_9014992_0 Cobalamin biosynthesis protein CobT K09883 - 6.6.1.2 3.803e-240 758.0
WH2_k127_9014992_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 586.0
WH2_k127_9014992_10 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 357.0
WH2_k127_9014992_11 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000953 221.0
WH2_k127_9014992_12 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000009883 209.0
WH2_k127_9014992_13 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000003883 181.0
WH2_k127_9014992_14 membrane - - - 0.000000000000000000000000000000000000000000000007533 177.0
WH2_k127_9014992_15 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000006138 160.0
WH2_k127_9014992_16 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000003098 156.0
WH2_k127_9014992_17 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.00000000000000000000000000006261 129.0
WH2_k127_9014992_18 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000003883 97.0
WH2_k127_9014992_19 cheY-homologous receiver domain - - - 0.00000000000000007644 91.0
WH2_k127_9014992_2 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 582.0
WH2_k127_9014992_20 - - - - 0.0000000000000001004 88.0
WH2_k127_9014992_21 Domain of unknown function (DUF4437) - - - 0.000000001026 64.0
WH2_k127_9014992_3 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 573.0
WH2_k127_9014992_4 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 558.0
WH2_k127_9014992_5 Cache 3/Cache 2 fusion domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 526.0
WH2_k127_9014992_6 ABC transporter substrate-binding protein PnrA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 469.0
WH2_k127_9014992_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 404.0
WH2_k127_9014992_8 Histidine kinase K07648 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 424.0
WH2_k127_9014992_9 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 375.0
WH2_k127_9028743_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.062e-295 922.0
WH2_k127_9028743_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 593.0
WH2_k127_9028743_10 COG1317 Flagellar biosynthesis type III secretory pathway protein K02411 - - 0.00000000000000000000000003811 120.0
WH2_k127_9028743_11 Flagellar hook-length control protein FliK - - - 0.00000000000000000000002769 115.0
WH2_k127_9028743_12 Flagellar GTP-binding protein K02404 - - 0.00001132 51.0
WH2_k127_9028743_2 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 505.0
WH2_k127_9028743_3 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 508.0
WH2_k127_9028743_4 mitochondrial tRNA-specific 2-thiouridylase K21027 - 2.8.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 491.0
WH2_k127_9028743_5 Flagellar hook protein FlgE K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 342.0
WH2_k127_9028743_6 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000000000000000000002596 183.0
WH2_k127_9028743_7 Arabinose efflux permease family protein K19577 - - 0.000000000000000000000000000000000000000000001096 172.0
WH2_k127_9028743_8 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.0000000000000000000000000000000000000002267 152.0
WH2_k127_9028743_9 Protein of unknown function (DUF1153) - - - 0.0000000000000000000000000000000000001942 143.0
WH2_k127_9028829_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 6.025e-279 868.0
WH2_k127_9028829_1 Sodium Bile acid symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 349.0
WH2_k127_9028829_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 340.0
WH2_k127_9028829_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002198 245.0
WH2_k127_9028829_4 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000000000003758 225.0
WH2_k127_9028829_5 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.000000000004484 74.0
WH2_k127_9029144_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1080.0
WH2_k127_9029144_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 7.16e-303 953.0
WH2_k127_9029144_10 RimK-like ATPgrasp N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 474.0
WH2_k127_9029144_11 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 433.0
WH2_k127_9029144_12 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 359.0
WH2_k127_9029144_13 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 338.0
WH2_k127_9029144_14 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 337.0
WH2_k127_9029144_15 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 336.0
WH2_k127_9029144_16 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 328.0
WH2_k127_9029144_17 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 321.0
WH2_k127_9029144_18 Pfam:DUF4102 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 328.0
WH2_k127_9029144_19 enzyme of poly-gamma-glutamate biosynthesis (capsule formation) K01929,K07282 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 321.0
WH2_k127_9029144_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 3.686e-285 884.0
WH2_k127_9029144_20 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007329 297.0
WH2_k127_9029144_21 Belongs to the UPF0758 family K03630 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 289.0
WH2_k127_9029144_22 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 289.0
WH2_k127_9029144_23 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008386 282.0
WH2_k127_9029144_24 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008475 262.0
WH2_k127_9029144_25 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 266.0
WH2_k127_9029144_26 Ornithine cyclodeaminase/mu-crystallin family K01750,K19743 - 1.5.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000008946 259.0
WH2_k127_9029144_27 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000001974 205.0
WH2_k127_9029144_29 Glutaredoxin K07390 - - 0.000000000000000000000000000000000000000000000000000002479 192.0
WH2_k127_9029144_3 response to antibiotic - - - 2.338e-225 732.0
WH2_k127_9029144_30 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000006339 164.0
WH2_k127_9029144_31 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000001398 175.0
WH2_k127_9029144_32 DSBA-like thioredoxin domain K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000377 173.0
WH2_k127_9029144_33 integral membrane protein - - - 0.00000000000000000000000000000000000001071 149.0
WH2_k127_9029144_34 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000002336 153.0
WH2_k127_9029144_35 BolA-like protein - - - 0.000000000000000000000000000000501 124.0
WH2_k127_9029144_36 Domain of unknown function (DUF1476) - - - 0.00000000000000000000000000000533 122.0
WH2_k127_9029144_37 TfoX N-terminal domain - - - 0.0000000000000000000000000003399 119.0
WH2_k127_9029144_38 PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - 0.000000000000000000000000004543 114.0
WH2_k127_9029144_39 Cytochrome P460 - - - 0.00000000000000000000001898 111.0
WH2_k127_9029144_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 2.458e-219 687.0
WH2_k127_9029144_40 Phosphotransferase enzyme family - - - 0.00000000000000003814 93.0
WH2_k127_9029144_41 chemotaxis K03406 - - 0.00000000000006836 74.0
WH2_k127_9029144_43 - - - - 0.0000000009616 64.0
WH2_k127_9029144_45 ParB-like nuclease domain K03497 - - 0.0000005483 56.0
WH2_k127_9029144_46 - - - - 0.00007285 51.0
WH2_k127_9029144_47 F subunit of K+-transporting ATPase (Potass_KdpF) - - - 0.0001442 49.0
WH2_k127_9029144_48 Pfam Prophage CP4-57 regulatory K07733 - - 0.0008695 50.0
WH2_k127_9029144_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 600.0
WH2_k127_9029144_6 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 546.0
WH2_k127_9029144_7 PFAM beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 505.0
WH2_k127_9029144_8 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 481.0
WH2_k127_9029144_9 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 457.0
WH2_k127_9030147_0 ABC-type Fe3 transport system permease component K02011 - - 1.397e-210 668.0
WH2_k127_9030147_1 Na+/Pi-cotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 600.0
WH2_k127_9030147_2 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 345.0
WH2_k127_9030147_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000000000000000008918 210.0
WH2_k127_9030147_4 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.000000000000000000000000000000000009509 141.0
WH2_k127_9030147_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000002554 85.0
WH2_k127_9048036_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.067e-276 861.0
WH2_k127_9048036_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.698e-261 814.0
WH2_k127_9048036_10 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000007081 227.0
WH2_k127_9048036_11 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000004971 210.0
WH2_k127_9048036_12 LysE type translocator - - - 0.000000000000000000000000000000000000000004349 162.0
WH2_k127_9048036_13 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000001106 156.0
WH2_k127_9048036_14 shape-determining protein K03571 - - 0.000000000000000000000000000000000000768 145.0
WH2_k127_9048036_15 MaoC like domain - - - 0.0000000000000000000000000000000000842 138.0
WH2_k127_9048036_16 dehydratase - - - 0.000000000000000000000000000000001675 139.0
WH2_k127_9048036_17 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000002281 128.0
WH2_k127_9048036_18 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000003627 96.0
WH2_k127_9048036_19 Putative sugar-binding domain - - - 0.0000000000000000007394 97.0
WH2_k127_9048036_2 belongs to the aldehyde dehydrogenase family - - - 4.498e-249 779.0
WH2_k127_9048036_20 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000008095 76.0
WH2_k127_9048036_21 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.000000000002561 70.0
WH2_k127_9048036_22 - - - - 0.0000000002287 63.0
WH2_k127_9048036_3 COG0768 cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 1.273e-205 657.0
WH2_k127_9048036_4 AMP-binding enzyme C-terminal domain K00666 - - 3.783e-195 623.0
WH2_k127_9048036_5 Rod shape-determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 602.0
WH2_k127_9048036_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 493.0
WH2_k127_9048036_7 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 453.0
WH2_k127_9048036_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 383.0
WH2_k127_9048036_9 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000003261 244.0
WH2_k127_9076_0 Strictosidine synthase K10440 - - 6.675e-286 894.0
WH2_k127_9076_1 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 5.774e-214 671.0
WH2_k127_9076_10 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 319.0
WH2_k127_9076_11 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 308.0
WH2_k127_9076_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 306.0
WH2_k127_9076_13 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002125 303.0
WH2_k127_9076_14 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000425 258.0
WH2_k127_9076_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000002349 228.0
WH2_k127_9076_2 ABC transporter - - - 1.127e-209 668.0
WH2_k127_9076_3 AMP-binding enzyme C-terminal domain K01895,K08295 - 6.2.1.1,6.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 497.0
WH2_k127_9076_4 PFAM aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 427.0
WH2_k127_9076_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 391.0
WH2_k127_9076_6 CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 370.0
WH2_k127_9076_7 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 355.0
WH2_k127_9076_8 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 323.0
WH2_k127_9076_9 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 314.0
WH2_k127_9091758_0 DNA topoisomerase type IA central domain protein K03169 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 447.0
WH2_k127_9091758_1 2OG-Fe dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 308.0
WH2_k127_9091758_2 Protein of unknown function (DUF2937) - - - 0.000000000000000000000000005753 116.0
WH2_k127_9091758_3 NUDIX domain - - - 0.0000002157 54.0
WH2_k127_9095336_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1195.0
WH2_k127_9095336_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 1.652e-281 873.0
WH2_k127_9095336_10 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 415.0
WH2_k127_9095336_11 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 410.0
WH2_k127_9095336_12 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 419.0
WH2_k127_9095336_13 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 418.0
WH2_k127_9095336_14 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 402.0
WH2_k127_9095336_15 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 395.0
WH2_k127_9095336_16 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 382.0
WH2_k127_9095336_17 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 386.0
WH2_k127_9095336_18 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 366.0
WH2_k127_9095336_19 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 351.0
WH2_k127_9095336_2 Sugar (and other) transporter - - - 5.924e-257 807.0
WH2_k127_9095336_20 Helix-turn-helix domain, rpiR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 337.0
WH2_k127_9095336_21 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 321.0
WH2_k127_9095336_22 Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 317.0
WH2_k127_9095336_23 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 289.0
WH2_k127_9095336_24 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000002834 274.0
WH2_k127_9095336_25 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000006664 276.0
WH2_k127_9095336_26 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000832 276.0
WH2_k127_9095336_27 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002077 259.0
WH2_k127_9095336_28 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001797 262.0
WH2_k127_9095336_29 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000004974 212.0
WH2_k127_9095336_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.909e-251 795.0
WH2_k127_9095336_30 PFAM regulatory protein TetR K09017 - - 0.00000000000000000000000000000000000000000000000002256 190.0
WH2_k127_9095336_31 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002098 176.0
WH2_k127_9095336_32 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000001018 134.0
WH2_k127_9095336_4 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 5.314e-227 717.0
WH2_k127_9095336_5 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 604.0
WH2_k127_9095336_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 511.0
WH2_k127_9095336_7 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 478.0
WH2_k127_9095336_8 PFAM binding-protein-dependent transport systems inner membrane component K13890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 436.0
WH2_k127_9095336_9 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 426.0
WH2_k127_9125259_0 de-polymerase K05973 - 3.1.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 539.0
WH2_k127_9125259_1 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K10021,K10025 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 381.0
WH2_k127_9125259_2 Bacterial periplasmic substrate-binding proteins K10018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 323.0
WH2_k127_9125259_3 ABC transporter (Permease K10019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 316.0
WH2_k127_9125259_4 ABC transporter K10020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 299.0
WH2_k127_9125259_5 Belongs to the UPF0260 family K09160 - - 0.000000000000000000000000000000000000000000000000000000000000001608 220.0
WH2_k127_9125259_6 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000003686 207.0
WH2_k127_9125259_7 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000164 190.0
WH2_k127_9131815_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 1.7e-234 740.0
WH2_k127_9131815_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 411.0
WH2_k127_9131815_2 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 378.0
WH2_k127_9131815_3 Permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 380.0
WH2_k127_9131815_4 branched-chain amino acid transport K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 377.0
WH2_k127_9131815_5 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001353 293.0
WH2_k127_9134994_0 FMN-dependent dehydrogenase K00101,K15054 - 1.1.2.3,1.1.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 600.0
WH2_k127_9134994_1 Transposase zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 465.0
WH2_k127_9134994_10 methyl-accepting chemotaxis K03406 - - 0.0000000000000003616 90.0
WH2_k127_9134994_2 ATPase with chaperone activity K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 388.0
WH2_k127_9134994_3 ATPase with chaperone activity K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 357.0
WH2_k127_9134994_4 - - - - 0.000000000000000000000000000000000000000000000000000000000004292 216.0
WH2_k127_9134994_5 2-oxohepta-3-ene-1,7-dioic acid hydratase K02509,K02554 - 4.2.1.80 0.00000000000000000000000000000000000000000000000000000001542 210.0
WH2_k127_9134994_6 - - - - 0.0000000000000000000000000000000000000000000007768 169.0
WH2_k127_9134994_7 GNaT family - - - 0.00000000000000000000000000000000000000009258 162.0
WH2_k127_9134994_8 - - - - 0.000000000000000000000000001658 113.0
WH2_k127_9134994_9 - - - - 0.00000000000000000002344 98.0
WH2_k127_915639_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 6.961e-288 894.0
WH2_k127_915639_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 345.0
WH2_k127_915639_10 PFAM Cell Wall Hydrolase K01449 - 3.5.1.28 0.0003759 47.0
WH2_k127_915639_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 357.0
WH2_k127_915639_3 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001367 301.0
WH2_k127_915639_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002059 265.0
WH2_k127_915639_5 Outer membrane protein W K07275 - - 0.0000000000000000000000000000000000000000000000000000000009783 208.0
WH2_k127_915639_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000003203 202.0
WH2_k127_915639_7 MaoC like domain - - - 0.0000000000000000000000000000000000000000000003262 178.0
WH2_k127_915639_8 TRAP-type C4-dicarboxylate transport system periplasmic component K21395 - - 0.00000000000000000000004873 111.0
WH2_k127_915639_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000002845 98.0
WH2_k127_9171501_0 methyl-accepting chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 536.0
WH2_k127_9171501_1 Phosphoribosylglycinamide synthetase, C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 512.0
WH2_k127_9171501_10 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016491,GO:0016614,GO:0018130,GO:0019438,GO:0019748,GO:0042469,GO:0043385,GO:0043386,GO:0044237,GO:0044249,GO:0044550,GO:0045460,GO:0045461,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901376,GO:1901378,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001512 250.0
WH2_k127_9171501_11 PFAM regulatory protein ArsR - - - 0.0000000000000000000000000000000000000000000000008104 177.0
WH2_k127_9171501_12 BON domain - - - 0.000000000000000000004197 100.0
WH2_k127_9171501_13 Aminotransferase class I and II K00813,K00832 - 2.6.1.1,2.6.1.57 0.00000000000001078 74.0
WH2_k127_9171501_14 PRC-barrel domain - - - 0.00000004696 64.0
WH2_k127_9171501_15 Protein of unknown function (DUF2934) - - - 0.0002 53.0
WH2_k127_9171501_2 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 459.0
WH2_k127_9171501_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 417.0
WH2_k127_9171501_4 Major facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 345.0
WH2_k127_9171501_5 Iron-containing redox enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 340.0
WH2_k127_9171501_6 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001244 292.0
WH2_k127_9171501_7 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002548 278.0
WH2_k127_9171501_8 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002158 280.0
WH2_k127_9171501_9 PFAM Aldose 1-epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007835 273.0
WH2_k127_9196175_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 8.3e-268 833.0
WH2_k127_9196175_1 glucuronate isomerase K01812 - 5.3.1.12 1.241e-241 775.0
WH2_k127_9196175_10 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 383.0
WH2_k127_9196175_11 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 375.0
WH2_k127_9196175_12 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 351.0
WH2_k127_9196175_13 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 347.0
WH2_k127_9196175_14 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 328.0
WH2_k127_9196175_15 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 296.0
WH2_k127_9196175_16 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005235 261.0
WH2_k127_9196175_17 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002121 245.0
WH2_k127_9196175_18 Permeases of the drug metabolite transporter (DMT) superfamily K15268 - - 0.00000000000000000000000000000000000000000000000000000000000000001485 237.0
WH2_k127_9196175_19 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000001881 233.0
WH2_k127_9196175_2 monooxygenase - - - 1.069e-221 694.0
WH2_k127_9196175_20 Protein of unknown function (DUF523) - - - 0.00000000000000000000000000000000000000000000000000001632 192.0
WH2_k127_9196175_21 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000003783 184.0
WH2_k127_9196175_22 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.000000000000000000000000000000000000000000002251 169.0
WH2_k127_9196175_23 Protein of unknown function (DUF3303) - - - 0.000000000000000000000000000000000000003382 147.0
WH2_k127_9196175_24 COG3293 Transposase and inactivated derivatives K07492 - - 0.0000000000000000000000000000007981 124.0
WH2_k127_9196175_25 Transposase DDE domain - - - 0.000004807 51.0
WH2_k127_9196175_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04091 - 1.14.14.5 6.715e-201 632.0
WH2_k127_9196175_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.37e-200 630.0
WH2_k127_9196175_5 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 600.0
WH2_k127_9196175_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 516.0
WH2_k127_9196175_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 465.0
WH2_k127_9196175_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 437.0
WH2_k127_9196175_9 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 439.0
WH2_k127_9203452_0 Dehydratase family K01690 - 4.2.1.12 3.631e-245 791.0
WH2_k127_9203452_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.019e-210 666.0
WH2_k127_9203452_10 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000002006 218.0
WH2_k127_9203452_11 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000002583 188.0
WH2_k127_9203452_2 PFAM Branched-chain amino acid transport system permease component K10544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 502.0
WH2_k127_9203452_3 ABC transporter substrate binding protein K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 447.0
WH2_k127_9203452_4 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 386.0
WH2_k127_9203452_5 Transporter K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 338.0
WH2_k127_9203452_6 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002632 278.0
WH2_k127_9203452_7 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003755 272.0
WH2_k127_9203452_8 transcriptional regulator K19337 - - 0.0000000000000000000000000000000000000000000000000000000000000000000033 248.0
WH2_k127_9203452_9 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000007529 235.0
WH2_k127_9247408_0 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 572.0
WH2_k127_9247408_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 516.0
WH2_k127_9247408_2 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 439.0
WH2_k127_9247408_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 412.0
WH2_k127_9247408_4 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 414.0
WH2_k127_9247408_5 RNA ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 318.0
WH2_k127_9247408_6 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002471 278.0
WH2_k127_9247408_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003241 238.0
WH2_k127_9247408_8 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00002116 50.0
WH2_k127_9247473_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 466.0
WH2_k127_9247473_1 GGDEF domain K01768,K02488,K07676,K10715,K20976 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3,2.7.7.65,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006876 278.0
WH2_k127_9247473_2 Ami_2 K00788,K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 2.5.1.3,3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000001125 268.0
WH2_k127_9247473_3 of the drug metabolite transporter (DMT) superfamily K15268 - - 0.0000000000000000000000000000000000000000000000000000000000001295 224.0
WH2_k127_9247473_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000001093 91.0
WH2_k127_9247473_5 - - - - 0.0000000008459 68.0
WH2_k127_9247473_6 Alpha beta hydrolase - - - 0.0001846 53.0
WH2_k127_9250727_0 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 566.0
WH2_k127_9250727_1 Ornithine cyclodeaminase/mu-crystallin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 555.0
WH2_k127_9250727_10 histidine utilization repressor K05836 - - 0.000000000000000000000000000000000000000000000000000000006925 203.0
WH2_k127_9250727_11 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000008909 120.0
WH2_k127_9250727_2 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 495.0
WH2_k127_9250727_3 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 451.0
WH2_k127_9250727_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 347.0
WH2_k127_9250727_5 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 332.0
WH2_k127_9250727_6 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 338.0
WH2_k127_9250727_7 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 322.0
WH2_k127_9250727_8 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002972 283.0
WH2_k127_9250727_9 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001799 250.0
WH2_k127_9279638_0 Virulence factor SrfB - - - 3.816e-287 913.0
WH2_k127_9279638_1 Putative bacterial virulence factor - - - 3.206e-200 663.0
WH2_k127_9279638_2 Virulence effector protein - - - 0.0000000000000000000000000000001365 130.0
WH2_k127_9279638_3 Major Facilitator Superfamily - - - 0.000002684 61.0
WH2_k127_931820_0 Bacterial protein of unknown function (DUF839) K07093 - - 4.582e-319 988.0
WH2_k127_931820_1 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 1.767e-241 768.0
WH2_k127_931820_10 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 309.0
WH2_k127_931820_11 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 291.0
WH2_k127_931820_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000557 281.0
WH2_k127_931820_13 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000004073 243.0
WH2_k127_931820_14 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000001165 213.0
WH2_k127_931820_15 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000001757 220.0
WH2_k127_931820_16 Fe-S protein - - - 0.0000000000000000000000000000000000000000000000000000000002011 211.0
WH2_k127_931820_17 Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source K01483 - 4.3.2.3 0.00000000000000000000000000000000000000000000000000000001464 204.0
WH2_k127_931820_18 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000002362 199.0
WH2_k127_931820_19 Transcriptional regulator, GntR family - - - 0.00000000000000000000000000000000000000000000000000002667 197.0
WH2_k127_931820_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 551.0
WH2_k127_931820_20 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000232 122.0
WH2_k127_931820_21 Transcriptional regulator PadR-like family - - - 0.0007856 46.0
WH2_k127_931820_3 Belongs to the allantoicase family K01477 - 3.5.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 466.0
WH2_k127_931820_4 Belongs to the ABC transporter superfamily K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 400.0
WH2_k127_931820_5 transporter, permease K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 390.0
WH2_k127_931820_6 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 372.0
WH2_k127_931820_7 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 340.0
WH2_k127_931820_8 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 333.0
WH2_k127_931820_9 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 321.0
WH2_k127_9323899_0 AMP-binding enzyme K00666,K20034 - 6.2.1.44 2.278e-254 801.0
WH2_k127_9323899_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 585.0
WH2_k127_9323899_10 Sporulation related domain - - - 0.000000000002644 72.0
WH2_k127_9323899_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 430.0
WH2_k127_9323899_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 294.0
WH2_k127_9323899_4 PFAM flavin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004873 257.0
WH2_k127_9323899_5 glycosyl - - - 0.00000000000000000000000000000000000000000000000000000000000000000001069 248.0
WH2_k127_9323899_6 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000001993 165.0
WH2_k127_9323899_7 - - - - 0.0000000000000000000000000000000000217 146.0
WH2_k127_9323899_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596 - 4.1.1.64 0.00000000000000000000000000005466 117.0
WH2_k127_9323899_9 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000004554 114.0
WH2_k127_9360285_0 Histidine kinase K07646 - 2.7.13.3 0.0 1095.0
WH2_k127_9360285_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.33e-226 712.0
WH2_k127_9360285_10 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000001395 211.0
WH2_k127_9360285_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000001578 194.0
WH2_k127_9360285_13 Protein of unknown function (DUF1244) K09948 - - 0.00000000000000000000000000000000000000000000004284 171.0
WH2_k127_9360285_14 cheY-homologous receiver domain - - - 0.00000000000000000000000000000002219 141.0
WH2_k127_9360285_15 PAS domain - - - 0.00000000001156 74.0
WH2_k127_9360285_2 Aspartate tyrosine aromatic aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 592.0
WH2_k127_9360285_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 419.0
WH2_k127_9360285_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 327.0
WH2_k127_9360285_5 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 327.0
WH2_k127_9360285_6 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004596 280.0
WH2_k127_9360285_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003367 271.0
WH2_k127_9360285_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000214 242.0
WH2_k127_9360285_9 FCD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001352 234.0
WH2_k127_9402509_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.023e-302 942.0
WH2_k127_9402509_1 Belongs to the UbiD family K03182 - 4.1.1.98 8.095e-289 897.0
WH2_k127_9402509_10 - - - - 0.0000000000000000000000000000000000000000000000000000000008165 216.0
WH2_k127_9402509_11 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000003641 207.0
WH2_k127_9402509_12 diguanylate cyclase activity - - - 0.0000000000000000000000000000000000000000005247 178.0
WH2_k127_9402509_13 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000009708 139.0
WH2_k127_9402509_14 PAS fold - - - 0.00000000000000000000000000000008459 143.0
WH2_k127_9402509_15 beta-lactamase activity K07126 - - 0.000000002911 70.0
WH2_k127_9402509_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 628.0
WH2_k127_9402509_3 Zn-dependent proteases and their inactivated homologs K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 537.0
WH2_k127_9402509_4 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 334.0
WH2_k127_9402509_5 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002018 284.0
WH2_k127_9402509_6 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000001286 258.0
WH2_k127_9402509_7 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001613 249.0
WH2_k127_9402509_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002161 254.0
WH2_k127_9402509_9 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000002259 229.0
WH2_k127_9467626_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1581.0
WH2_k127_9467626_1 Belongs to the CarA family K01956 - 6.3.5.5 1.603e-197 636.0
WH2_k127_9467626_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000676 235.0
WH2_k127_9467626_11 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000001977 158.0
WH2_k127_9467626_13 Methyltransferase domain - - - 0.00000000000000000000000000000000007539 147.0
WH2_k127_9467626_14 - - - - 0.00000000000000000000000000000005808 130.0
WH2_k127_9467626_15 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000002461 117.0
WH2_k127_9467626_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 484.0
WH2_k127_9467626_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 485.0
WH2_k127_9467626_4 Oxidoreductase FAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 403.0
WH2_k127_9467626_5 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 398.0
WH2_k127_9467626_6 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 363.0
WH2_k127_9467626_7 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 330.0
WH2_k127_9467626_8 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 300.0
WH2_k127_9467626_9 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 253.0
WH2_k127_9467930_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 2.135e-281 874.0
WH2_k127_9467930_1 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 3.494e-264 827.0
WH2_k127_9467930_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20971 - - 0.0000000000000000000000000000000000000000000000000000000000000001803 245.0
WH2_k127_9467930_11 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000982 192.0
WH2_k127_9467930_12 COG0835 Chemotaxis signal transduction protein K03408 - - 0.000000000000000000000000000000000000000000005026 185.0
WH2_k127_9467930_13 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000001049 141.0
WH2_k127_9467930_14 transcriptional regulator - - - 0.000000000000000000000000000000003168 138.0
WH2_k127_9467930_15 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000003726 113.0
WH2_k127_9467930_16 - - - - 0.00000000000003201 76.0
WH2_k127_9467930_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 6.728e-222 708.0
WH2_k127_9467930_3 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 526.0
WH2_k127_9467930_4 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 497.0
WH2_k127_9467930_5 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 498.0
WH2_k127_9467930_6 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 407.0
WH2_k127_9467930_7 COG1126 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 407.0
WH2_k127_9467930_8 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 343.0
WH2_k127_9467930_9 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 301.0
WH2_k127_9468366_0 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 9.01e-282 878.0
WH2_k127_9468366_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K13584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 406.0
WH2_k127_9468366_10 TIGRFAM Diguanylate cyclase - - - 0.00000000000000001388 96.0
WH2_k127_9468366_11 - - - - 0.00000000000000002039 87.0
WH2_k127_9468366_2 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 399.0
WH2_k127_9468366_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 405.0
WH2_k127_9468366_4 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 383.0
WH2_k127_9468366_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 356.0
WH2_k127_9468366_6 COG0784 FOG CheY-like receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000005091 204.0
WH2_k127_9468366_7 COG0835 Chemotaxis signal transduction protein K03408 - - 0.000000000000000000000000000000000000000000000000000000002291 209.0
WH2_k127_9468366_8 Exopolysaccharide synthesis, ExoD - - - 0.0000000000000000000000000000000004372 141.0
WH2_k127_9468366_9 - - - - 0.000000000000000000001435 100.0
WH2_k127_9493121_0 Oxidoreductase NAD-binding domain K02613,K07006 - - 1.785e-307 956.0
WH2_k127_9493121_1 peptidase - - - 1.815e-203 644.0
WH2_k127_9493121_10 DNA-binding response regulator K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002305 261.0
WH2_k127_9493121_11 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006271 257.0
WH2_k127_9493121_12 transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000008288 218.0
WH2_k127_9493121_13 Export-related chaperone CsaA K06878 - - 0.000000000000000000000000000000000000000000000000007882 183.0
WH2_k127_9493121_14 - - - - 0.00000000000000000000000000000000000000000005118 173.0
WH2_k127_9493121_15 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000000000000000006182 162.0
WH2_k127_9493121_16 transcriptional regulator - - - 0.0000000000000000000000000000000000000001222 157.0
WH2_k127_9493121_17 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000002548 148.0
WH2_k127_9493121_18 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.00000000000000000000000000000000000000474 151.0
WH2_k127_9493121_19 Phasin protein - - - 0.00000000000000000003285 97.0
WH2_k127_9493121_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 485.0
WH2_k127_9493121_20 Las17-binding protein actin regulator - - - 0.00000000000000000006707 98.0
WH2_k127_9493121_21 PAS domain - - - 0.0000000000000004256 89.0
WH2_k127_9493121_3 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 475.0
WH2_k127_9493121_4 Histidine kinase K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 392.0
WH2_k127_9493121_5 Glutathione S-transferase K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0006950,GO:0008150,GO:0009635,GO:0009636,GO:0016740,GO:0016765,GO:0032991,GO:0042221,GO:0042802,GO:0042803,GO:0046983,GO:0050896 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 345.0
WH2_k127_9493121_6 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 342.0
WH2_k127_9493121_7 Protein of unknown function (DUF1348) K09958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 299.0
WH2_k127_9493121_8 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 297.0
WH2_k127_9493121_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003355 283.0
WH2_k127_9495197_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 0.0 1502.0
WH2_k127_9495197_1 Extracellular solute-binding protein, family 5 K02035 - - 3.16e-218 691.0
WH2_k127_9495197_10 nlpA lipoprotein K02073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 331.0
WH2_k127_9495197_11 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 309.0
WH2_k127_9495197_12 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 287.0
WH2_k127_9495197_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001746 284.0
WH2_k127_9495197_14 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000009285 234.0
WH2_k127_9495197_15 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.000000000000000000000000000000000000000000000000000000000000001148 224.0
WH2_k127_9495197_16 Bacterial transcriptional repressor C-terminal K16137 - - 0.000000000000000000000000000000000000000000000000000000002098 209.0
WH2_k127_9495197_2 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 501.0
WH2_k127_9495197_3 iron ascorbate-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 468.0
WH2_k127_9495197_4 VWA domain containing CoxE-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 473.0
WH2_k127_9495197_5 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 461.0
WH2_k127_9495197_6 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 407.0
WH2_k127_9495197_7 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 402.0
WH2_k127_9495197_8 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 390.0
WH2_k127_9495197_9 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 366.0
WH2_k127_9515670_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 9.083e-304 947.0
WH2_k127_9515670_1 Belongs to the DEAD box helicase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 541.0
WH2_k127_9515670_10 17 kDa outer membrane surface antigen - - - 0.00000000000000000000000000000000000000000000000000002361 193.0
WH2_k127_9515670_11 Isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000000000901 183.0
WH2_k127_9515670_12 Transposase - - - 0.000000000000000000000000000000000000000001663 156.0
WH2_k127_9515670_13 Secreted repeat of unknown function - - - 0.000000000000000000000000000000000000000002366 159.0
WH2_k127_9515670_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000001318 152.0
WH2_k127_9515670_15 Acyl-CoA hydrolase K10806 - - 0.000000000000000000000000000000000000003498 150.0
WH2_k127_9515670_16 Response regulator receiver - - - 0.00000000000000000000000000001584 125.0
WH2_k127_9515670_17 Transposase - - - 0.0000000000000000006789 88.0
WH2_k127_9515670_18 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000000000004605 73.0
WH2_k127_9515670_19 - - - - 0.00000001816 65.0
WH2_k127_9515670_2 Alkaline phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 536.0
WH2_k127_9515670_20 COG0643 Chemotaxis protein histidine kinase and related kinases - - - 0.0000001511 60.0
WH2_k127_9515670_21 AraC-like ligand binding domain - - - 0.000002578 49.0
WH2_k127_9515670_22 Transposase DDE domain - - - 0.000005754 49.0
WH2_k127_9515670_23 - - - - 0.0002688 47.0
WH2_k127_9515670_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 526.0
WH2_k127_9515670_4 Bacterial extracellular solute-binding protein K02064 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 465.0
WH2_k127_9515670_5 COG1178 ABC-type Fe3 transport system permease component K02063 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 428.0
WH2_k127_9515670_6 ATPases associated with a variety of cellular activities K02062 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 284.0
WH2_k127_9515670_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000009005 227.0
WH2_k127_9515670_8 tRNA 3'-terminal CCA addition - - - 0.0000000000000000000000000000000000000000000000000000000007359 210.0
WH2_k127_9515670_9 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000000001177 198.0
WH2_k127_9557819_0 4Fe-4S dicluster domain K17723 - 1.3.1.1 2.41e-232 723.0
WH2_k127_9557819_1 belongs to the aldehyde dehydrogenase family K10217 - 1.2.1.32,1.2.1.85 8.797e-220 691.0
WH2_k127_9557819_10 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 375.0
WH2_k127_9557819_11 acetylesterase activity K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 362.0
WH2_k127_9557819_12 acetylesterase activity K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 347.0
WH2_k127_9557819_13 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 331.0
WH2_k127_9557819_14 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 303.0
WH2_k127_9557819_15 PFAM Allophanate hydrolase subunit 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001783 296.0
WH2_k127_9557819_16 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009919 286.0
WH2_k127_9557819_17 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002911 278.0
WH2_k127_9557819_18 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000001283 256.0
WH2_k127_9557819_19 ABC transporter substrate-binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000001228 251.0
WH2_k127_9557819_2 Phosphohydrolase-associated domain K01129 - 3.1.5.1 5.431e-199 628.0
WH2_k127_9557819_20 Allophanate hydrolase subunit 1 K01457 - 3.5.1.54 0.000000000000000000000000000000000000000000000000000000000000008442 224.0
WH2_k127_9557819_21 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000008854 225.0
WH2_k127_9557819_22 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000000000009193 224.0
WH2_k127_9557819_23 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000328 220.0
WH2_k127_9557819_24 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000006163 205.0
WH2_k127_9557819_25 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000004189 187.0
WH2_k127_9557819_26 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.0000000000000000000000000000000000000000001771 175.0
WH2_k127_9557819_27 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000002056 138.0
WH2_k127_9557819_28 transcriptional regulator K02624 - - 0.00000000000000000000000000000003239 141.0
WH2_k127_9557819_29 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.0000000000000000000000000005094 115.0
WH2_k127_9557819_3 Peptidase family M20/M25/M40 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 591.0
WH2_k127_9557819_30 Domain of unknown function (DUF4142) K08995 - - 0.00000000002074 73.0
WH2_k127_9557819_4 3-carboxyethylcatechol 2,3-dioxygenase activity K00455,K15058,K15059 - 1.13.11.15,1.13.11.74,1.13.11.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 527.0
WH2_k127_9557819_5 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 512.0
WH2_k127_9557819_6 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 496.0
WH2_k127_9557819_7 TonB dependent receptor K16087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 479.0
WH2_k127_9557819_8 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 413.0
WH2_k127_9557819_9 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 403.0
WH2_k127_9643485_0 Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism K00372,K02567 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 - 0.0 1579.0
WH2_k127_9643485_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.662e-303 948.0
WH2_k127_9643485_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 378.0
WH2_k127_9643485_11 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 361.0
WH2_k127_9643485_12 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 350.0
WH2_k127_9643485_13 Siderophore-interacting FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 344.0
WH2_k127_9643485_14 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 312.0
WH2_k127_9643485_15 Adenylate guanylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 319.0
WH2_k127_9643485_16 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 301.0
WH2_k127_9643485_17 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.0000000000000000000000000000000000000000000000000000000000000002336 228.0
WH2_k127_9643485_18 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000001093 192.0
WH2_k127_9643485_19 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000000000007266 178.0
WH2_k127_9643485_2 receptor K02014 - - 2.162e-294 919.0
WH2_k127_9643485_20 COG3143 Chemotaxis protein K03414 - - 0.00000000000000000000000000000000000000000002848 171.0
WH2_k127_9643485_21 Extensin-like protein C-terminus - - - 0.000000000000000000000000000000000000000001834 163.0
WH2_k127_9643485_22 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000000001461 158.0
WH2_k127_9643485_23 - - - - 0.00000000000000000000000001168 118.0
WH2_k127_9643485_24 Uncharacterized protein conserved in bacteria (DUF2312) - - - 0.000000000000000000000009985 104.0
WH2_k127_9643485_25 NapD protein - - - 0.0000000000000001013 83.0
WH2_k127_9643485_26 Nitrate reductase K02571 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000005129 81.0
WH2_k127_9643485_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 1.362e-213 696.0
WH2_k127_9643485_4 ATP-dependent helicase K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 523.0
WH2_k127_9643485_5 III protein, CoA-transferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 496.0
WH2_k127_9643485_6 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 463.0
WH2_k127_9643485_7 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 421.0
WH2_k127_9643485_8 NapC/NirT cytochrome c family, N-terminal region K02569 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 412.0
WH2_k127_9643485_9 Bacterial regulatory helix-turn-helix proteins, AraC family K07506 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 412.0
WH2_k127_9644042_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.127e-199 635.0
WH2_k127_9644042_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 527.0
WH2_k127_9644042_10 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009175 275.0
WH2_k127_9644042_11 cysteine dioxygenase type I - - - 0.000000000000000000000000000000000000000000000000000000000000000000002838 254.0
WH2_k127_9644042_12 enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000002135 214.0
WH2_k127_9644042_2 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 479.0
WH2_k127_9644042_3 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 470.0
WH2_k127_9644042_4 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 456.0
WH2_k127_9644042_5 Binding-protein-dependent transport system inner membrane component K02033 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 447.0
WH2_k127_9644042_6 membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 410.0
WH2_k127_9644042_7 ATPases associated with a variety of cellular activities K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 401.0
WH2_k127_9644042_8 PFAM ABC transporter K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 335.0
WH2_k127_9644042_9 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001286 278.0
WH2_k127_9648985_0 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 6.157e-204 643.0
WH2_k127_9648985_1 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 477.0
WH2_k127_9648985_2 Binding-protein-dependent transport system inner membrane component K02050,K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 427.0
WH2_k127_9648985_3 ATPases associated with a variety of cellular activities K02049,K15578 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 398.0
WH2_k127_9648985_4 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 383.0
WH2_k127_9648985_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576,K22067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 323.0
WH2_k127_9648985_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 309.0
WH2_k127_9648985_7 response regulator K07183 - - 0.0000000000000000000000000000000000000000000001089 188.0
WH2_k127_9652354_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1430.0
WH2_k127_9652354_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.137e-250 844.0
WH2_k127_9652354_10 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 596.0
WH2_k127_9652354_11 Catalyzes the hydrolysis of short-chain aliphatic amides to their K01426,K01455 - 3.5.1.4,3.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 584.0
WH2_k127_9652354_12 RimK-like ATPgrasp N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 592.0
WH2_k127_9652354_13 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 577.0
WH2_k127_9652354_14 Bacterial regulatory protein, Fis family K10912 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 572.0
WH2_k127_9652354_15 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 558.0
WH2_k127_9652354_16 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 557.0
WH2_k127_9652354_17 Transport of potassium into the cell K03549 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 549.0
WH2_k127_9652354_18 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 519.0
WH2_k127_9652354_19 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 497.0
WH2_k127_9652354_2 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 1.217e-237 756.0
WH2_k127_9652354_20 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 485.0
WH2_k127_9652354_21 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 490.0
WH2_k127_9652354_22 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 464.0
WH2_k127_9652354_23 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 467.0
WH2_k127_9652354_24 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 450.0
WH2_k127_9652354_25 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 439.0
WH2_k127_9652354_26 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 422.0
WH2_k127_9652354_27 NMT1/THI5 like K15598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 404.0
WH2_k127_9652354_28 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 417.0
WH2_k127_9652354_29 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 391.0
WH2_k127_9652354_3 Sigma-54 interaction domain K07712 - - 1.853e-232 726.0
WH2_k127_9652354_30 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 380.0
WH2_k127_9652354_31 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 384.0
WH2_k127_9652354_32 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 384.0
WH2_k127_9652354_33 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 392.0
WH2_k127_9652354_34 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 355.0
WH2_k127_9652354_35 Catalyzes the transamination of D-amino acids and their alpha-keto acids K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 341.0
WH2_k127_9652354_36 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 332.0
WH2_k127_9652354_37 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 329.0
WH2_k127_9652354_38 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 317.0
WH2_k127_9652354_39 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 302.0
WH2_k127_9652354_4 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 4.539e-223 730.0
WH2_k127_9652354_40 Glucosamine-6-phosphate K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 312.0
WH2_k127_9652354_41 transcriptional regulator K03566 GO:0001130,GO:0001131,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005709 280.0
WH2_k127_9652354_42 Siderophore-interacting FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008755 275.0
WH2_k127_9652354_43 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001446 254.0
WH2_k127_9652354_44 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006779 251.0
WH2_k127_9652354_45 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002259 249.0
WH2_k127_9652354_46 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000005866 222.0
WH2_k127_9652354_47 cephalosporin hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000002149 224.0
WH2_k127_9652354_48 FCD - - - 0.000000000000000000000000000000000000000000000000000000000008761 214.0
WH2_k127_9652354_49 Histidine kinase K20975 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000004189 225.0
WH2_k127_9652354_5 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 9.639e-212 679.0
WH2_k127_9652354_50 Protein of unknown function (DUF3225) - - - 0.0000000000000000000000000000000000000000000000000003513 188.0
WH2_k127_9652354_51 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000002345 188.0
WH2_k127_9652354_52 Disulfide bond formation protein - - - 0.00000000000000000000000000000000000000000000002649 177.0
WH2_k127_9652354_53 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000000004142 172.0
WH2_k127_9652354_54 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000005081 181.0
WH2_k127_9652354_55 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000003418 174.0
WH2_k127_9652354_56 Hemerythrin - - - 0.0000000000000000000000000000000000000001648 160.0
WH2_k127_9652354_57 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000002176 148.0
WH2_k127_9652354_58 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000001408 164.0
WH2_k127_9652354_59 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000004321 144.0
WH2_k127_9652354_6 H( )-stimulated, divalent metal cation uptake system K03322 - - 4.78e-209 657.0
WH2_k127_9652354_60 Amidohydrolase family - - - 0.000000000000000000000000000000000001325 147.0
WH2_k127_9652354_61 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 - 2.7.7.65 0.000000000000000000000000000000000001845 154.0
WH2_k127_9652354_62 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000007418 139.0
WH2_k127_9652354_63 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000006203 125.0
WH2_k127_9652354_64 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000001319 115.0
WH2_k127_9652354_65 LTXXQ motif family protein - - - 0.000000000000000000000000002619 119.0
WH2_k127_9652354_66 Trypsin-like serine protease - - - 0.00000000000000000000006943 113.0
WH2_k127_9652354_68 An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH K00240,K09159 GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 1.3.5.1,1.3.5.4 0.00000000000000001964 98.0
WH2_k127_9652354_69 Protein of unknown function (DUF4089) - - - 0.0000000001016 70.0
WH2_k127_9652354_7 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 6.234e-209 657.0
WH2_k127_9652354_70 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K15599 - - 0.00000001568 56.0
WH2_k127_9652354_71 - - - - 0.0000001034 55.0
WH2_k127_9652354_72 RES - - - 0.0003443 44.0
WH2_k127_9652354_8 Amidase K01457 - 3.5.1.54 1.384e-202 646.0
WH2_k127_9652354_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.438e-202 643.0
WH2_k127_9691823_0 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 2.684e-305 959.0
WH2_k127_9691823_1 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 1.198e-204 642.0
WH2_k127_9691823_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 473.0
WH2_k127_9691823_3 Metallopeptidase family M24 K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 441.0
WH2_k127_9691823_4 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 368.0
WH2_k127_9691823_5 Protein of unknown function (DUF1513) K09947 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001933 286.0
WH2_k127_9691823_6 Imelysin K07338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004613 260.0
WH2_k127_9691823_7 Thiol oxidoreductase - - - 0.00000000000000000000000000000000000000007059 151.0
WH2_k127_9712947_0 gamma-aminobutyric acid catabolic process - - - 8.062e-259 803.0
WH2_k127_9712947_1 Transcriptional regulatory protein, C terminal K08282 - 2.7.11.1 7.245e-224 732.0
WH2_k127_9712947_10 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 369.0
WH2_k127_9712947_11 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 356.0
WH2_k127_9712947_12 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 346.0
WH2_k127_9712947_13 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005113 263.0
WH2_k127_9712947_14 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000003406 152.0
WH2_k127_9712947_15 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000000000009484 151.0
WH2_k127_9712947_16 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000002561 147.0
WH2_k127_9712947_17 - - - - 0.000000000000000002261 89.0
WH2_k127_9712947_18 Transposase K07493 - - 0.00000000000000006382 83.0
WH2_k127_9712947_19 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000002334 80.0
WH2_k127_9712947_2 Zn-dependent alcohol dehydrogenases K13953,K18382 - 1.1.1.1 6.003e-205 641.0
WH2_k127_9712947_20 Haem-degrading - - - 0.0000000007082 61.0
WH2_k127_9712947_22 - - - - 0.000000002082 67.0
WH2_k127_9712947_23 - - - - 0.00000005405 59.0
WH2_k127_9712947_24 PFAM helix-turn-helix domain protein - - - 0.000001474 57.0
WH2_k127_9712947_3 Carbon-nitrogen hydrolase K01502 - 3.5.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 581.0
WH2_k127_9712947_4 Major Facilitator Superfamily K13021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 555.0
WH2_k127_9712947_5 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 520.0
WH2_k127_9712947_6 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 458.0
WH2_k127_9712947_7 restriction endonuclease K07454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 455.0
WH2_k127_9712947_8 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 425.0
WH2_k127_9712947_9 AraC-binding-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 370.0
WH2_k127_9721232_0 Flavin-binding monooxygenase-like - - - 1.339e-292 906.0
WH2_k127_9721232_1 CoA-binding domain protein - - - 3.445e-233 743.0
WH2_k127_9721232_10 COG4335 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003416 246.0
WH2_k127_9721232_11 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000001024 240.0
WH2_k127_9721232_12 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000006721 230.0
WH2_k127_9721232_13 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000005896 170.0
WH2_k127_9721232_14 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000004583 157.0
WH2_k127_9721232_15 Domain of unknown function (DUF1127) - - - 0.0000007522 57.0
WH2_k127_9721232_16 Belongs to the short-chain dehydrogenases reductases (SDR) family K05783 - 1.3.1.25 0.0003437 49.0
WH2_k127_9721232_2 PFAM AMP-dependent synthetase and ligase K00666,K20034 - 6.2.1.44 1.438e-218 704.0
WH2_k127_9721232_3 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 454.0
WH2_k127_9721232_4 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 355.0
WH2_k127_9721232_5 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 361.0
WH2_k127_9721232_6 SMP-30/Gluconolaconase/LRE-like region K13874 - 3.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 311.0
WH2_k127_9721232_7 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 301.0
WH2_k127_9721232_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 291.0
WH2_k127_9721232_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002181 259.0
WH2_k127_9744687_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.466e-283 909.0
WH2_k127_9744687_1 symbiont process K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 574.0
WH2_k127_9744687_10 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000001513 173.0
WH2_k127_9744687_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000001341 126.0
WH2_k127_9744687_12 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000007735 104.0
WH2_k127_9744687_13 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000008113 77.0
WH2_k127_9744687_2 Amidohydrolase family K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 555.0
WH2_k127_9744687_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 514.0
WH2_k127_9744687_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 370.0
WH2_k127_9744687_5 C-terminal domain of 1-Cys peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 340.0
WH2_k127_9744687_6 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008689 248.0
WH2_k127_9744687_7 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001283 217.0
WH2_k127_9744687_8 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000002989 207.0
WH2_k127_9744687_9 serine-type endopeptidase activity K01312 - 3.4.21.4 0.000000000000000000000000000000000000000000000000006932 203.0
WH2_k127_9764388_0 ABC-type dipeptide transport system periplasmic component K02035 - - 8.456e-273 846.0
WH2_k127_9764388_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 9.024e-266 826.0
WH2_k127_9764388_10 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 580.0
WH2_k127_9764388_11 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 563.0
WH2_k127_9764388_12 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 518.0
WH2_k127_9764388_13 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 510.0
WH2_k127_9764388_14 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 496.0
WH2_k127_9764388_15 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 490.0
WH2_k127_9764388_16 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009781 470.0
WH2_k127_9764388_17 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 456.0
WH2_k127_9764388_18 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 421.0
WH2_k127_9764388_19 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 414.0
WH2_k127_9764388_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.672e-260 811.0
WH2_k127_9764388_20 acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 364.0
WH2_k127_9764388_21 Binding-protein-dependent transport system inner membrane component K02053,K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 309.0
WH2_k127_9764388_22 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006893 279.0
WH2_k127_9764388_23 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009508 259.0
WH2_k127_9764388_24 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000001227 221.0
WH2_k127_9764388_25 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000187 192.0
WH2_k127_9764388_26 Belongs to the ABC transporter superfamily K02052 - - 0.00002208 49.0
WH2_k127_9764388_3 ABC-type dipeptide transport system, periplasmic component K02035 - - 2.566e-241 755.0
WH2_k127_9764388_4 Luciferase-like monooxygenase - - - 4.077e-230 720.0
WH2_k127_9764388_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 6.605e-226 717.0
WH2_k127_9764388_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K17228 - 1.14.14.35 1.947e-208 654.0
WH2_k127_9764388_7 ABC-type dipeptide transport system, periplasmic component K02035 - - 6.019e-198 631.0
WH2_k127_9764388_8 ABC-type dipeptide transport system, periplasmic component K02035 - - 4.566e-197 627.0
WH2_k127_9764388_9 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 573.0
WH2_k127_9801145_0 PrkA AAA domain K07180 - - 0.0 1043.0
WH2_k127_9801145_1 FAD dependent oxidoreductase - - - 8.916e-241 749.0
WH2_k127_9801145_10 COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 412.0
WH2_k127_9801145_11 Belongs to the enoyl-CoA hydratase isomerase family K08299,K16426 - 4.2.1.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 381.0
WH2_k127_9801145_12 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 359.0
WH2_k127_9801145_13 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 351.0
WH2_k127_9801145_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001596 277.0
WH2_k127_9801145_15 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000002004 174.0
WH2_k127_9801145_16 UPF0126 domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000008598 142.0
WH2_k127_9801145_17 Aspartyl asparaginyl beta-hydroxylase K12979 - - 0.000000000000000000000000001112 123.0
WH2_k127_9801145_18 peroxiredoxin activity K03386 - 1.11.1.15 0.00000000000000000000000002285 114.0
WH2_k127_9801145_19 Nitrile hydratase - - - 0.000003341 55.0
WH2_k127_9801145_2 SpoVR like protein K06415 - - 2.198e-218 689.0
WH2_k127_9801145_3 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 4.462e-204 644.0
WH2_k127_9801145_4 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 567.0
WH2_k127_9801145_5 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 550.0
WH2_k127_9801145_6 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 452.0
WH2_k127_9801145_7 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 440.0
WH2_k127_9801145_8 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 410.0
WH2_k127_9801145_9 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 411.0
WH2_k127_9809666_0 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 2.019e-271 847.0
WH2_k127_9809666_1 Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source K01505 - 3.5.99.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 486.0
WH2_k127_9809666_2 Circularly permuted ATP-grasp type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 480.0
WH2_k127_9809666_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000001828 213.0
WH2_k127_9809666_4 type VI secretion protein K11903 - - 0.0009424 46.0
WH2_k127_9820935_0 Biotin carboxylase C-terminal domain K01968,K13777 - 6.4.1.4,6.4.1.5 3.726e-269 847.0
WH2_k127_9820935_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.249e-253 809.0
WH2_k127_9820935_10 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 425.0
WH2_k127_9820935_11 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 411.0
WH2_k127_9820935_12 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 298.0
WH2_k127_9820935_13 Carboxylesterase family K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000075 241.0
WH2_k127_9820935_14 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000004775 231.0
WH2_k127_9820935_15 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000006505 232.0
WH2_k127_9820935_16 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000002882 220.0
WH2_k127_9820935_17 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000232 186.0
WH2_k127_9820935_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000007132 145.0
WH2_k127_9820935_19 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000001057 134.0
WH2_k127_9820935_2 enoyl-CoA hydratase K15513 - 4.1.2.44 2.718e-248 777.0
WH2_k127_9820935_20 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000308 132.0
WH2_k127_9820935_21 ChrR Cupin-like domain - - - 0.00000000000002803 81.0
WH2_k127_9820935_3 Carboxyl transferase domain K13778 - 6.4.1.5 2.036e-244 764.0
WH2_k127_9820935_4 synthetase - - - 4.733e-214 675.0
WH2_k127_9820935_5 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 7.988e-201 638.0
WH2_k127_9820935_6 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 577.0
WH2_k127_9820935_7 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 501.0
WH2_k127_9820935_8 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 508.0
WH2_k127_9820935_9 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 488.0
WH2_k127_9871590_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.689e-315 978.0
WH2_k127_9871590_1 PFAM extracellular solute-binding protein family 5 K02035 - - 4.109e-296 914.0
WH2_k127_9871590_10 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 383.0
WH2_k127_9871590_11 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 383.0
WH2_k127_9871590_12 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 331.0
WH2_k127_9871590_13 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 296.0
WH2_k127_9871590_14 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 287.0
WH2_k127_9871590_15 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008362 275.0
WH2_k127_9871590_16 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000004336 276.0
WH2_k127_9871590_17 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000254 241.0
WH2_k127_9871590_18 - - - - 0.000000000000000000000000000000000000000000000000000000000003559 220.0
WH2_k127_9871590_19 transcriptional K03719 - - 0.0000000000000000000000000000000000000004907 153.0
WH2_k127_9871590_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.739e-239 767.0
WH2_k127_9871590_20 Domain of unknown function (DUF3817) - - - 0.00000000000000000000000001311 112.0
WH2_k127_9871590_21 Uncharacterised protein family (UPF0093) - - - 0.00000000000000000000005565 107.0
WH2_k127_9871590_22 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000005996 99.0
WH2_k127_9871590_23 Lipocalin-like domain - - - 0.0000003009 57.0
WH2_k127_9871590_3 Belongs to the ABC transporter superfamily K02031,K02032 - - 2.538e-235 745.0
WH2_k127_9871590_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 522.0
WH2_k127_9871590_5 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 482.0
WH2_k127_9871590_6 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 486.0
WH2_k127_9871590_7 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 476.0
WH2_k127_9871590_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 437.0
WH2_k127_9871590_9 helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 386.0
WH2_k127_9895060_0 formate dehydrogenase K00123 - 1.17.1.9 0.0 1626.0
WH2_k127_9895060_1 Major facilitator superfamily - - - 2.204e-301 930.0
WH2_k127_9895060_10 - - - - 0.00000000000000000000000000000002472 133.0
WH2_k127_9895060_11 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.0000000000000000000007719 102.0
WH2_k127_9895060_12 Subtilase family - - - 0.00001377 57.0
WH2_k127_9895060_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 7.057e-263 826.0
WH2_k127_9895060_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.011e-227 749.0
WH2_k127_9895060_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 582.0
WH2_k127_9895060_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 466.0
WH2_k127_9895060_6 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 317.0
WH2_k127_9895060_7 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000002178 230.0
WH2_k127_9895060_8 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000007526 204.0
WH2_k127_9895060_9 - - - - 0.00000000000000000000000000000000000001307 153.0
WH2_k127_9945582_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.209e-226 710.0
WH2_k127_9945582_1 belongs to the aldehyde dehydrogenase family - - - 4.04e-211 664.0
WH2_k127_9945582_2 Iron-containing alcohol dehydrogenase K00001,K00043 - 1.1.1.1,1.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 584.0
WH2_k127_9945582_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 384.0
WH2_k127_9945582_4 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 328.0
WH2_k127_9945582_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 322.0
WH2_k127_9945582_6 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001499 252.0
WH2_k127_9945582_7 Glycine D-amino acid oxidases (deaminating) K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000528 247.0
WH2_k127_9945582_8 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000002044 205.0
WH2_k127_999067_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 3.513e-267 834.0
WH2_k127_999067_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 422.0
WH2_k127_999067_2 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 388.0
WH2_k127_999067_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 410.0
WH2_k127_999067_4 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 352.0
WH2_k127_999067_5 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000194 289.0
WH2_k127_999067_6 transcriptional K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000007895 190.0
WH2_k127_999067_7 uracil DNA glycosylase K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000005366 173.0
WH2_k127_999067_8 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000003682 82.0