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Overview

ID MAG04109
Name WH2_bin.11
Sample SMP0107
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Desulfuromonadia
Order Geobacterales
Family DSM-12255
Genus
Species
Assembly information
Completeness (%) 68.37
Contamination (%) 0.83
GC content (%) 60.0
N50 (bp) 3,030
Genome size (bp) 1,486,020

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1670

Gene name Description KEGG GOs EC E-value Score Sequence
WH2_k127_10002079_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 1029.0
WH2_k127_10002079_1 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 406.0
WH2_k127_10020388_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1087.0
WH2_k127_10020388_1 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 432.0
WH2_k127_10020388_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 332.0
WH2_k127_10020388_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000219 284.0
WH2_k127_10020388_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000003157 159.0
WH2_k127_10020388_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000002158 158.0
WH2_k127_10049609_0 PFAM Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 512.0
WH2_k127_10049609_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000003689 212.0
WH2_k127_10049609_2 histidine kinase HAMP region domain protein - - - 0.00000000000000003856 96.0
WH2_k127_10063436_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 2.767e-310 962.0
WH2_k127_10063436_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 360.0
WH2_k127_10088255_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 484.0
WH2_k127_10088255_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 451.0
WH2_k127_10088255_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 379.0
WH2_k127_10088255_3 - - - - 0.00000000000000000000000001311 112.0
WH2_k127_10088255_4 - - - - 0.0000000000000000000001398 100.0
WH2_k127_10088255_5 Sporulation and spore germination - - - 0.000000005027 61.0
WH2_k127_10110323_0 PFAM Rh family protein ammonium transporter K03320 - - 1.428e-229 715.0
WH2_k127_10110323_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 490.0
WH2_k127_10110601_0 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000004654 171.0
WH2_k127_10110601_1 - - - - 0.0000000000000000000000000000000000006858 149.0
WH2_k127_10110601_2 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.000001304 58.0
WH2_k127_10120273_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 3.612e-243 754.0
WH2_k127_10120273_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 411.0
WH2_k127_10120273_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 301.0
WH2_k127_10120273_3 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000000000000000000000000000000000000004523 195.0
WH2_k127_10120273_4 HNH nucleases - - - 0.000000000000000000000000000000000000000002315 157.0
WH2_k127_10120273_5 cytochrome c - - - 0.000000000000000000000000000000006253 129.0
WH2_k127_10120273_6 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000000000000007869 109.0
WH2_k127_10128404_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 497.0
WH2_k127_10136262_0 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 323.0
WH2_k127_10136262_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002667 252.0
WH2_k127_10136262_2 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000004519 99.0
WH2_k127_10136262_3 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000007672 87.0
WH2_k127_10144850_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 2.147e-233 737.0
WH2_k127_10144850_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 464.0
WH2_k127_10144850_2 calcium, potassium:sodium antiporter activity K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 362.0
WH2_k127_10144850_3 Na+/Pi-cotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000001148 239.0
WH2_k127_10144850_4 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000000000000000000000000000001013 205.0
WH2_k127_10197417_0 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 452.0
WH2_k127_10197417_1 ABC-2 family transporter protein K09694 - - 0.0000000000000000000000000000000000000001583 153.0
WH2_k127_10197417_2 Protein of unknown function (DUF3300) - - - 0.00000000004805 64.0
WH2_k127_10200186_0 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002521 283.0
WH2_k127_10200186_1 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000000000000000000000000000001423 213.0
WH2_k127_10200186_2 Acyltransferase K12251 - 3.5.1.53 0.0000000000112 64.0
WH2_k127_10207434_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 468.0
WH2_k127_10207434_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000001074 190.0
WH2_k127_10207434_2 YtxH-like protein - - - 0.00000000000000006102 83.0
WH2_k127_10221525_0 SMART Elongator protein 3 MiaB NifB - - - 4.4e-278 865.0
WH2_k127_10221525_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 546.0
WH2_k127_10221525_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000004345 85.0
WH2_k127_10221525_4 Ribosomal protein S9/S16 K02996 - - 0.00000000000000003204 81.0
WH2_k127_10247609_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 405.0
WH2_k127_10247609_1 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 339.0
WH2_k127_10247609_2 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 301.0
WH2_k127_10247609_3 Major Facilitator Superfamily - - - 0.000000000000000008809 83.0
WH2_k127_10247609_4 Protein of unknown function (DUF3185) - - - 0.00000000000001256 75.0
WH2_k127_10257593_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 6.412e-309 953.0
WH2_k127_10257593_1 Acetyl-CoA hydrolase/transferase N-terminal domain K01067,K18118 - 2.8.3.18,3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000003141 217.0
WH2_k127_10257593_2 SprT-like family - - - 0.0000000000000000000000000000000000000001151 159.0
WH2_k127_10261708_0 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 485.0
WH2_k127_10261708_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 389.0
WH2_k127_10261708_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 347.0
WH2_k127_10261708_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 311.0
WH2_k127_10270455_0 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 402.0
WH2_k127_10280397_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 416.0
WH2_k127_10280397_1 histidine kinase, HAMP K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000001125 177.0
WH2_k127_10280397_2 PFAM Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000005376 159.0
WH2_k127_10283051_0 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000002022 246.0
WH2_k127_10283051_1 FecR protein - - - 0.0000000000000000009543 91.0
WH2_k127_10285069_0 Protein of unknown function, DUF480 K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 296.0
WH2_k127_10285069_1 Parallel beta-helix repeats - - - 0.00000000000000000000004205 113.0
WH2_k127_10308311_0 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 366.0
WH2_k127_10308311_1 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000018 143.0
WH2_k127_10308311_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000001861 77.0
WH2_k127_10329236_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000009884 224.0
WH2_k127_10336431_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 511.0
WH2_k127_10336431_1 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 434.0
WH2_k127_10379374_0 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 539.0
WH2_k127_10379374_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000004222 222.0
WH2_k127_10379374_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000373 128.0
WH2_k127_10379374_3 FecR protein - - - 0.00000000000000000000000000001032 124.0
WH2_k127_10386691_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 475.0
WH2_k127_10386691_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002814 253.0
WH2_k127_10386691_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000484 117.0
WH2_k127_10475047_0 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 484.0
WH2_k127_10478191_0 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 377.0
WH2_k127_10478191_1 Transcriptional regulatory protein, C terminal K07664 - - 0.000000000000000000000000000000000000000000000000000000000004296 214.0
WH2_k127_10478191_2 Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000001654 175.0
WH2_k127_10528493_0 belongs to the aldehyde dehydrogenase family - - - 2.214e-198 625.0
WH2_k127_10528493_1 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000001106 106.0
WH2_k127_10542068_0 Elongator protein 3, MiaB family, Radical SAM K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 464.0
WH2_k127_10542068_1 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 423.0
WH2_k127_10542068_2 - - - - 0.00000000000000000000000000000000000000000002287 162.0
WH2_k127_10542068_4 acetyltransferase - - - 0.0000000000000006694 80.0
WH2_k127_10542068_6 Transcriptional regulator - - - 0.000000000001523 69.0
WH2_k127_10542068_7 Transcriptional regulator - - - 0.000005384 49.0
WH2_k127_10559303_0 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 7.875e-207 644.0
WH2_k127_10559303_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000008398 239.0
WH2_k127_10559303_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000001046 77.0
WH2_k127_10568121_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 424.0
WH2_k127_10568121_1 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 416.0
WH2_k127_10568121_2 Guanylyl transferase CofC like K09931 - - 0.0000000000000000000000000000000000000000000000000000000003416 209.0
WH2_k127_10576480_1 HEPN domain - - - 0.00000000000000000001097 97.0
WH2_k127_10606847_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1155.0
WH2_k127_10636605_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 584.0
WH2_k127_10646136_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001856 290.0
WH2_k127_10646136_2 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000001992 219.0
WH2_k127_10646136_3 Histidine kinase K13040 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001759 207.0
WH2_k127_10646136_4 Protein of unknown function (DUF3106) - - - 0.0000001445 61.0
WH2_k127_10649713_0 General secretory system II, protein E domain protein K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 512.0
WH2_k127_10649713_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000001642 169.0
WH2_k127_10649713_2 PFAM Radical SAM domain protein - - - 0.00000000000000001338 83.0
WH2_k127_10696066_0 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 538.0
WH2_k127_10696066_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 512.0
WH2_k127_10696066_2 RNA-metabolising metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 337.0
WH2_k127_10696066_3 - - - - 0.0000000000000004447 92.0
WH2_k127_10795880_0 SMART Nucleotide binding protein, PINc K07175 - - 2.145e-233 727.0
WH2_k127_10795880_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 436.0
WH2_k127_10795880_2 TIGRFAM cysteine desulfurase family protein K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 338.0
WH2_k127_10795880_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 296.0
WH2_k127_10808969_0 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 606.0
WH2_k127_10808969_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000004338 192.0
WH2_k127_10808969_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000002135 162.0
WH2_k127_1112771_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 335.0
WH2_k127_1112771_1 PFAM DivIVA family protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000966 201.0
WH2_k127_1112771_2 YGGT family K02221 - - 0.0000000000000000000000000000000000000004609 151.0
WH2_k127_1112771_3 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000001121 102.0
WH2_k127_1112771_4 IMP dehydrogenase activity K07182 - - 0.00000000000008934 74.0
WH2_k127_1113221_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0 1030.0
WH2_k127_1113221_1 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 486.0
WH2_k127_1113221_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006796 263.0
WH2_k127_1113221_3 - - - - 0.000000000000000000002299 96.0
WH2_k127_1130823_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 597.0
WH2_k127_1130823_1 family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 315.0
WH2_k127_1130823_3 Rubrerythrin - - - 0.00001425 47.0
WH2_k127_1197760_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1291.0
WH2_k127_1197760_1 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 334.0
WH2_k127_1197760_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009377 257.0
WH2_k127_1218695_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 1.515e-217 683.0
WH2_k127_1218695_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000246 274.0
WH2_k127_122383_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 522.0
WH2_k127_122383_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 511.0
WH2_k127_122383_2 Protoglobin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 458.0
WH2_k127_122383_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000008409 256.0
WH2_k127_122383_4 6 heme-binding sites - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003803 248.0
WH2_k127_122383_5 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000000000006815 138.0
WH2_k127_122383_7 SlyX K03745 - - 0.0000000008365 66.0
WH2_k127_1225964_0 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 350.0
WH2_k127_1225964_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000001825 230.0
WH2_k127_1225964_2 Regulatory protein, FmdB family - - - 0.000000005857 58.0
WH2_k127_1227060_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 372.0
WH2_k127_1227060_1 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000001153 216.0
WH2_k127_1313658_0 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 457.0
WH2_k127_1313658_1 PFAM oxidoreductase nitrogenase, component 1 K02586 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 362.0
WH2_k127_1313658_2 Belongs to the P(II) protein family K02589 - - 0.000000000000000000000000000000000000000005939 164.0
WH2_k127_1313658_3 Belongs to the P(II) protein family K02590 - - 0.00000000000000000000000000000000000000003252 154.0
WH2_k127_1340605_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 375.0
WH2_k127_1340605_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 376.0
WH2_k127_1340605_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 351.0
WH2_k127_1340605_3 PFAM tRNA synthetase, class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005492 249.0
WH2_k127_1340605_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000489 132.0
WH2_k127_1365637_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1138.0
WH2_k127_1365637_1 HEAT repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 583.0
WH2_k127_1365637_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 481.0
WH2_k127_1365637_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 439.0
WH2_k127_1365637_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 370.0
WH2_k127_1365637_5 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000001132 214.0
WH2_k127_1365637_6 zinc-ribbon domain - - - 0.00000000000000000000000001552 114.0
WH2_k127_139740_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1012.0
WH2_k127_139740_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 332.0
WH2_k127_139740_2 Bacterial regulatory protein, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000372 216.0
WH2_k127_139740_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000005678 57.0
WH2_k127_1425294_0 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 299.0
WH2_k127_1425294_1 - - - - 0.00000000000000000000000000000000000000000000000000000001905 205.0
WH2_k127_1425294_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000001159 106.0
WH2_k127_1440962_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.0 1156.0
WH2_k127_1440962_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K05587 - 1.6.5.3 0.0 1128.0
WH2_k127_1440962_2 Aminotransferase class-III K01845 - 5.4.3.8 2.646e-236 737.0
WH2_k127_1440962_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 1.815e-217 678.0
WH2_k127_1440962_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 333.0
WH2_k127_1440962_5 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 314.0
WH2_k127_1440962_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001433 256.0
WH2_k127_1440962_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000000000000386 92.0
WH2_k127_1440962_8 ATP synthase I chain - - - 0.000002213 55.0
WH2_k127_1441312_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 398.0
WH2_k127_1441312_1 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 361.0
WH2_k127_1441312_2 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000007627 123.0
WH2_k127_1446526_0 Belongs to the GPI family K01810 - 5.3.1.9 4.976e-194 618.0
WH2_k127_1446526_1 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000000000000000000003788 239.0
WH2_k127_1446526_2 phosphorelay signal transduction system - - - 0.000000000006262 66.0
WH2_k127_1469932_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 432.0
WH2_k127_1469932_1 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 399.0
WH2_k127_1469932_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 293.0
WH2_k127_1469932_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000005054 160.0
WH2_k127_1469932_4 Protein of unknown function (DUF2723) - - - 0.00000000000000000000001067 111.0
WH2_k127_1471608_0 PFAM Sporulation stage II, protein E C-terminal K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 387.0
WH2_k127_1471608_1 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000007832 181.0
WH2_k127_1471608_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000176 88.0
WH2_k127_1516211_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 8.636e-224 698.0
WH2_k127_1516211_1 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002331 226.0
WH2_k127_1516211_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000002816 223.0
WH2_k127_1516211_3 Probable molybdopterin binding domain K03638,K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000001489 209.0
WH2_k127_1516211_4 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000000000000000000000001876 178.0
WH2_k127_1516211_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.00000000000001068 76.0
WH2_k127_1547880_0 Diguanylate cyclase - - - 4.994e-264 827.0
WH2_k127_1547880_1 PFAM transglutaminase family protein cysteine peptidase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 299.0
WH2_k127_1565050_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 487.0
WH2_k127_1565050_1 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000006359 260.0
WH2_k127_1565050_2 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000003355 126.0
WH2_k127_1575406_0 phosphorelay signal transduction system - - - 4.167e-197 633.0
WH2_k127_1575406_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 342.0
WH2_k127_1575406_2 PFAM Rubrerythrin - - - 0.0000002875 54.0
WH2_k127_1602262_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 3.625e-261 809.0
WH2_k127_1602262_1 PFAM Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000003812 222.0
WH2_k127_1613641_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 494.0
WH2_k127_1613641_1 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 321.0
WH2_k127_1625628_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 542.0
WH2_k127_1625628_1 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000005236 198.0
WH2_k127_1643895_0 argininosuccinate synthase activity K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 3.934e-243 754.0
WH2_k127_1643895_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000002719 161.0
WH2_k127_1651923_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 360.0
WH2_k127_1651923_1 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 303.0
WH2_k127_1651923_2 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000000000006209 208.0
WH2_k127_1651923_3 Protein of unknown function (DUF1475) - - - 0.000000000000000000000000000000000204 133.0
WH2_k127_1652674_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 433.0
WH2_k127_1652674_1 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000724 224.0
WH2_k127_1652674_2 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000005769 141.0
WH2_k127_1653000_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 516.0
WH2_k127_1653000_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 347.0
WH2_k127_1653000_2 PFAM Colicin V production protein K03558 - - 0.0000000000000000000000000000000000000000000000000000005908 199.0
WH2_k127_1653000_3 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000001663 184.0
WH2_k127_1653000_4 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000000000006542 156.0
WH2_k127_1653000_5 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000004131 116.0
WH2_k127_1702935_0 Isocitrate dehydrogenase NADP-dependent, monomeric type K00031 - 1.1.1.42 0.0 1286.0
WH2_k127_1706954_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 414.0
WH2_k127_1706954_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000232 265.0
WH2_k127_1706954_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000003583 265.0
WH2_k127_1707546_0 PFAM peptidase M29, aminopeptidase II K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 585.0
WH2_k127_1707546_1 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 317.0
WH2_k127_1707546_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000008191 115.0
WH2_k127_1718597_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 476.0
WH2_k127_1718597_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 351.0
WH2_k127_1792746_0 TIGRFAM ammonium transporter K03320 - - 1.098e-241 756.0
WH2_k127_1792746_1 Belongs to the P(II) protein family K04751 - - 0.000000000271 60.0
WH2_k127_1802613_0 manually curated K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 556.0
WH2_k127_1802613_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000002599 155.0
WH2_k127_1833991_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 334.0
WH2_k127_1833991_1 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000033 209.0
WH2_k127_1833991_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000001306 199.0
WH2_k127_1833991_3 cheY-homologous receiver domain - - - 0.0000000001776 68.0
WH2_k127_1866874_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.593e-235 736.0
WH2_k127_1866874_1 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 368.0
WH2_k127_1867458_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 462.0
WH2_k127_1867458_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 391.0
WH2_k127_1867458_2 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000000000000000000000000000000000000000001864 222.0
WH2_k127_1922775_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1690.0
WH2_k127_1922775_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.7.99.1 0.0 1022.0
WH2_k127_1922775_2 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 453.0
WH2_k127_1922775_3 cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 364.0
WH2_k127_1922775_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004245 257.0
WH2_k127_1922775_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003269 232.0
WH2_k127_1922775_6 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000004866 225.0
WH2_k127_1922775_7 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000001131 220.0
WH2_k127_1922775_8 Transcriptional regulator K02019,K05772 - - 0.000000000000000000000000000000000007913 140.0
WH2_k127_1939015_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 363.0
WH2_k127_1939015_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001862 211.0
WH2_k127_1939015_2 Na+/Pi-cotransporter K03324 - - 0.00000000000000000000000000000000000000000001074 167.0
WH2_k127_1939015_3 Belongs to the bacterial histone-like protein family K05788 - - 0.0000000000000000000000000000000000000001263 151.0
WH2_k127_1939015_4 - - - - 0.0000000000000002558 83.0
WH2_k127_1947485_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.886e-253 784.0
WH2_k127_1947485_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 481.0
WH2_k127_1977801_0 Belongs to the glutamate synthase family K22083 - 2.1.1.21 1.528e-308 948.0
WH2_k127_1977801_1 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 356.0
WH2_k127_1977801_2 4Fe-4S dicluster domain K00196,K05796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 295.0
WH2_k127_1984490_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004267 260.0
WH2_k127_1984490_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000004825 229.0
WH2_k127_2008627_0 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 1.528e-196 622.0
WH2_k127_2008627_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 356.0
WH2_k127_2008627_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003164 261.0
WH2_k127_2020924_0 Peptidase U62 modulator of DNA gyrase K03568 - - 3.155e-196 621.0
WH2_k127_2020924_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000001149 215.0
WH2_k127_202352_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 540.0
WH2_k127_202352_1 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005884 268.0
WH2_k127_202352_2 Acyl-ACP thioesterase - - - 0.0000000000000000000000000000000000000000000000000000000002093 211.0
WH2_k127_2074387_0 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 542.0
WH2_k127_2074387_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 487.0
WH2_k127_2074387_2 Heavy-metal-associated domain K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 313.0
WH2_k127_2088384_0 histidine kinase, HAMP K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 421.0
WH2_k127_2088384_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 385.0
WH2_k127_2088384_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 327.0
WH2_k127_2137472_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 528.0
WH2_k127_2137472_1 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009392 272.0
WH2_k127_2137472_2 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000001345 160.0
WH2_k127_2191715_0 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 7.014e-215 681.0
WH2_k127_2191715_1 PFAM CHAD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000009595 212.0
WH2_k127_2200769_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 561.0
WH2_k127_2200769_1 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000495 149.0
WH2_k127_2202790_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 542.0
WH2_k127_2202790_1 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 355.0
WH2_k127_2202790_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 354.0
WH2_k127_2214749_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 3.619e-227 711.0
WH2_k127_2214749_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 342.0
WH2_k127_2214749_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003402 272.0
WH2_k127_2214749_3 SAM-dependent RNA methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000003969 228.0
WH2_k127_2214749_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000005173 209.0
WH2_k127_2214749_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000182 167.0
WH2_k127_2214749_6 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000004005 151.0
WH2_k127_2214749_7 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000000007918 145.0
WH2_k127_2214749_8 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000004441 128.0
WH2_k127_2214749_9 Protein of unknown function (DUF3343) - - - 0.0000000000000000000000000000001348 125.0
WH2_k127_2254987_0 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 414.0
WH2_k127_2254987_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 302.0
WH2_k127_2254987_2 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000009695 100.0
WH2_k127_2286576_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.515e-263 824.0
WH2_k127_2286576_1 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 424.0
WH2_k127_2286576_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 306.0
WH2_k127_2287506_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 599.0
WH2_k127_2287506_1 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000809 212.0
WH2_k127_2345926_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007828 580.0
WH2_k127_2345926_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 406.0
WH2_k127_2345926_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001688 253.0
WH2_k127_2345926_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000007452 65.0
WH2_k127_2382224_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 2.164e-239 745.0
WH2_k127_2382224_1 Belongs to the CarA family K01956 - 6.3.5.5 3.132e-231 720.0
WH2_k127_2382224_2 PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 568.0
WH2_k127_2382224_3 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 503.0
WH2_k127_2382224_4 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 328.0
WH2_k127_2382224_5 Bifunctional protein PyrR K02825 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001732 278.0
WH2_k127_2382224_6 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000009989 254.0
WH2_k127_2382224_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000001719 173.0
WH2_k127_2395534_0 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 501.0
WH2_k127_2395534_1 4Fe-4S dicluster domain K08358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 314.0
WH2_k127_2395534_2 Molybdopterin oxidoreductase Fe4S4 domain K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000003655 192.0
WH2_k127_2395534_3 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000000000000000009934 169.0
WH2_k127_2395534_4 Psort location CytoplasmicMembrane, score - - - 0.000000000002365 68.0
WH2_k127_2472420_0 electron transfer flavoprotein, alpha subunit K03522 - - 2.569e-206 650.0
WH2_k127_2472420_1 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000001193 208.0
WH2_k127_2472420_2 4Fe-4S dicluster domain - - - 0.00000000000000844 76.0
WH2_k127_2490247_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K15022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.17.1.10 0.0 1162.0
WH2_k127_2490247_1 2Fe-2S iron-sulfur cluster binding domain K05299 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.17.1.10 2.192e-302 944.0
WH2_k127_2490247_2 Thermophilic metalloprotease (M29) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 492.0
WH2_k127_2490247_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000006657 241.0
WH2_k127_2498784_0 PFAM magnesium chelatase ChlI subunit K07391 - - 1.347e-255 795.0
WH2_k127_2498784_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000002225 209.0
WH2_k127_2513171_0 PFAM ParB domain protein nuclease K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 368.0
WH2_k127_2513171_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000003091 192.0
WH2_k127_2513171_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000001806 156.0
WH2_k127_2513171_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000001661 102.0
WH2_k127_2539548_0 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 417.0
WH2_k127_2539548_1 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 351.0
WH2_k127_2539548_3 Cytochrome c - - - 0.00000000002726 66.0
WH2_k127_2562898_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 369.0
WH2_k127_2562898_1 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 342.0
WH2_k127_25769_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 7.467e-222 693.0
WH2_k127_25769_1 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 407.0
WH2_k127_25769_2 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000001381 164.0
WH2_k127_25769_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000001786 111.0
WH2_k127_2634287_0 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 376.0
WH2_k127_2634287_1 PFAM ATP-binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009486 253.0
WH2_k127_2642756_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 340.0
WH2_k127_2642756_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 336.0
WH2_k127_2642756_2 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.0000000000000000000000000004825 115.0
WH2_k127_2660013_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 501.0
WH2_k127_2660013_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 314.0
WH2_k127_2660013_2 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 311.0
WH2_k127_2660013_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000005041 220.0
WH2_k127_2678479_0 DbpA RNA binding domain K05591 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000003298 233.0
WH2_k127_2678479_1 Protein of unknown function (DUF3185) - - - 0.000000000000543 70.0
WH2_k127_2678479_2 Bacterial protein of unknown function (DUF937) - - - 0.00002207 51.0
WH2_k127_2719567_0 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 346.0
WH2_k127_2719567_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003498 283.0
WH2_k127_2719999_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.819e-262 819.0
WH2_k127_2719999_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 612.0
WH2_k127_2719999_10 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 294.0
WH2_k127_2719999_11 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000958 283.0
WH2_k127_2719999_12 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000002198 228.0
WH2_k127_2719999_13 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000000000000000000000000000000000002866 224.0
WH2_k127_2719999_14 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000000000000000927 149.0
WH2_k127_2719999_15 Copper-exporting ATPase K17686 - 3.6.3.54 0.000000001507 63.0
WH2_k127_2719999_2 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 607.0
WH2_k127_2719999_3 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 582.0
WH2_k127_2719999_4 GTP-binding GTPase Middle Region K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 587.0
WH2_k127_2719999_5 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 460.0
WH2_k127_2719999_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 451.0
WH2_k127_2719999_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 441.0
WH2_k127_2719999_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 429.0
WH2_k127_2719999_9 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 392.0
WH2_k127_2725408_0 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 493.0
WH2_k127_2725408_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 493.0
WH2_k127_2725408_2 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009108 244.0
WH2_k127_2725408_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000003658 161.0
WH2_k127_2765028_0 response regulator K07712 - - 3.096e-195 613.0
WH2_k127_2765028_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003175 252.0
WH2_k127_2765028_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000002123 197.0
WH2_k127_2787999_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 379.0
WH2_k127_2787999_1 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 358.0
WH2_k127_2828586_0 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 513.0
WH2_k127_2828586_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 409.0
WH2_k127_2828586_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00006547 45.0
WH2_k127_2841410_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 7.731e-273 846.0
WH2_k127_2841410_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000002919 59.0
WH2_k127_2842895_0 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 574.0
WH2_k127_2842895_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000002239 263.0
WH2_k127_2842895_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000002252 185.0
WH2_k127_2842895_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000001199 154.0
WH2_k127_2853620_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 539.0
WH2_k127_2853620_1 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001024 276.0
WH2_k127_2853620_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000001764 177.0
WH2_k127_2860870_0 Putative RNA methylase family UPF0020 K15460 - 2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000000001772 243.0
WH2_k127_2860870_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000005998 233.0
WH2_k127_2860870_2 - - - - 0.0000000000000000000000000000000002402 133.0
WH2_k127_2860870_3 Protein of unknown function (DUF3343) - - - 0.0000000000000000000000000000000147 128.0
WH2_k127_2860870_4 Protein of unknown function (DUF721) - - - 0.00000000000000000000000006087 113.0
WH2_k127_2872752_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 604.0
WH2_k127_2874067_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.967e-205 648.0
WH2_k127_2888654_0 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 5.626e-246 763.0
WH2_k127_2888654_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 507.0
WH2_k127_2888654_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 449.0
WH2_k127_2888654_3 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 342.0
WH2_k127_2888654_5 Putative regulatory protein - - - 0.0000000000000000000000000000001481 125.0
WH2_k127_2888654_6 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000002832 49.0
WH2_k127_2929113_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.622e-226 706.0
WH2_k127_2929113_1 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000006184 134.0
WH2_k127_2929113_2 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.0000000000002344 70.0
WH2_k127_2947958_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 502.0
WH2_k127_2999098_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 592.0
WH2_k127_2999098_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 524.0
WH2_k127_2999098_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 423.0
WH2_k127_2999098_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000001868 188.0
WH2_k127_2999098_4 cheY-homologous receiver domain K02485 - - 0.000000000000000000000000000000000000000000000000002911 186.0
WH2_k127_2999098_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000002393 102.0
WH2_k127_2999098_6 Protein of unknown function (DUF1722) - - - 0.00002197 50.0
WH2_k127_3011697_0 TIGRFAM branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 595.0
WH2_k127_3011697_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000003327 138.0
WH2_k127_3026905_0 Sodium:solute symporter family K14393 - - 4.617e-227 713.0
WH2_k127_3026905_1 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 304.0
WH2_k127_3026905_2 Domain of unknown function (DUF4212) - - - 0.000000000000000000000116 100.0
WH2_k127_3056889_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1144.0
WH2_k127_3134166_0 DHHA2 K15986 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644 342.0
WH2_k127_3134166_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000002665 151.0
WH2_k127_3137701_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 8.48e-236 734.0
WH2_k127_3137701_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 280.0
WH2_k127_3137701_2 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003258 230.0
WH2_k127_3171550_0 Elongator protein 3, MiaB family, Radical SAM - - - 3.768e-245 762.0
WH2_k127_3171550_1 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000001042 218.0
WH2_k127_3175510_0 Protein of unknown function (DUF401) K09133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 545.0
WH2_k127_3175510_1 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 339.0
WH2_k127_3175510_2 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001105 256.0
WH2_k127_3175510_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000128 254.0
WH2_k127_3175510_4 Smr domain - - - 0.000000000000000000000000000000000000000000000000000000000001222 217.0
WH2_k127_3175510_5 Belongs to the UPF0260 family K09160 - - 0.000000000000000000000000000000000000002944 154.0
WH2_k127_3183996_0 sensor histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 298.0
WH2_k127_3188438_0 ABC transporter C-terminal domain K15738 - - 5.453e-285 890.0
WH2_k127_3188438_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003508 285.0
WH2_k127_3188438_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005477 284.0
WH2_k127_3228967_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.0 1238.0
WH2_k127_3228967_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K19516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 296.0
WH2_k127_3228967_2 Cysteine-rich domain - - - 0.000000000002409 68.0
WH2_k127_3236067_0 DHHA2 K15986 - 3.6.1.1 1.21e-210 661.0
WH2_k127_3236067_1 Threonyl and Alanyl tRNA synthetase second additional domain K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 504.0
WH2_k127_3266549_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 3.553e-197 617.0
WH2_k127_3266549_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 420.0
WH2_k127_3266549_2 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 374.0
WH2_k127_3266549_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0001859 46.0
WH2_k127_3267985_0 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 476.0
WH2_k127_3267985_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 445.0
WH2_k127_3317398_0 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 396.0
WH2_k127_3317398_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 373.0
WH2_k127_3317398_2 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000009124 257.0
WH2_k127_3362802_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 4.773e-196 621.0
WH2_k127_3362802_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000002223 60.0
WH2_k127_3391191_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 595.0
WH2_k127_3391191_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 481.0
WH2_k127_3391191_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 423.0
WH2_k127_3411388_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 474.0
WH2_k127_3411388_1 NUDIX domain - - - 0.00001094 49.0
WH2_k127_3422825_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 564.0
WH2_k127_3422825_1 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 411.0
WH2_k127_3422825_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 330.0
WH2_k127_3422825_3 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004267 267.0
WH2_k127_3422825_4 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000017 84.0
WH2_k127_343293_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 465.0
WH2_k127_343293_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001546 273.0
WH2_k127_343293_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000002256 256.0
WH2_k127_343293_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000197 241.0
WH2_k127_3490970_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 602.0
WH2_k127_3490970_1 - - - - 0.00000000000000000000000000000000003362 138.0
WH2_k127_3490970_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000004594 71.0
WH2_k127_3490970_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000002066 54.0
WH2_k127_3510021_0 PFAM Glycoside hydrolase 15-related - - - 0.0 1060.0
WH2_k127_3510021_1 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000000000000000000000001988 167.0
WH2_k127_3510021_2 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000005273 148.0
WH2_k127_3510021_3 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.00000000000000000004369 92.0
WH2_k127_3516036_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 552.0
WH2_k127_3516036_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 385.0
WH2_k127_3516036_2 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 338.0
WH2_k127_3516036_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003506 282.0
WH2_k127_3516036_4 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000000468 207.0
WH2_k127_3516036_5 TonB C terminal K03646,K03832 - - 0.000000000000000000000000000000000000000000000007501 186.0
WH2_k127_3516036_6 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000000000000007487 171.0
WH2_k127_3516036_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.00000000000000000002015 94.0
WH2_k127_3516036_8 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.000009069 47.0
WH2_k127_3519995_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 2.883e-287 889.0
WH2_k127_3519995_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 511.0
WH2_k127_3519995_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000009517 254.0
WH2_k127_3519995_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000005641 250.0
WH2_k127_3519995_4 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000001535 193.0
WH2_k127_3519995_5 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000003648 130.0
WH2_k127_3519995_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000002791 82.0
WH2_k127_3530639_0 FtsX-like permease family K02004 - - 2.754e-267 839.0
WH2_k127_3541975_0 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 415.0
WH2_k127_3541975_1 PFAM import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 361.0
WH2_k127_3541975_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000001035 203.0
WH2_k127_3545878_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 522.0
WH2_k127_3545878_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000008666 215.0
WH2_k127_3552593_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0 1027.0
WH2_k127_3571397_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 1.063e-230 732.0
WH2_k127_3571397_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 531.0
WH2_k127_3571397_2 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 517.0
WH2_k127_3571397_3 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003376 285.0
WH2_k127_3571397_4 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000007283 233.0
WH2_k127_3582092_0 Na H antiporter - - - 1.24e-203 640.0
WH2_k127_3582092_1 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 344.0
WH2_k127_3602031_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 423.0
WH2_k127_3602031_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 306.0
WH2_k127_3602031_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003022 265.0
WH2_k127_3602031_3 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001806 228.0
WH2_k127_3602031_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000004733 179.0
WH2_k127_3633301_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 342.0
WH2_k127_3633301_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 329.0
WH2_k127_3647136_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 499.0
WH2_k127_3647136_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002491 244.0
WH2_k127_3647136_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000399 213.0
WH2_k127_3659191_0 SMART Elongator protein 3 MiaB NifB K22227 - - 3.541e-228 709.0
WH2_k127_3659191_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008926 573.0
WH2_k127_3659191_2 Sensor histidine kinase, HAMP and PAS domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 540.0
WH2_k127_3663479_0 Pyridoxal-dependent decarboxylase conserved domain K01580 - 4.1.1.15 3.678e-252 788.0
WH2_k127_3663479_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 5.721e-218 689.0
WH2_k127_3663479_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000001867 185.0
WH2_k127_3678814_0 PFAM alpha amylase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 319.0
WH2_k127_3678814_1 permease K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 313.0
WH2_k127_3678814_2 Pfam:UPF0118 K03548 - - 0.0000000114 57.0
WH2_k127_3701438_0 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 598.0
WH2_k127_3701438_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 366.0
WH2_k127_3701438_2 response regulator K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 339.0
WH2_k127_3701438_4 formate transmembrane transporter activity K03459,K06212,K21993 GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015318,GO:0015499,GO:0015711,GO:0015718,GO:0015724,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.00009277 45.0
WH2_k127_3760242_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 539.0
WH2_k127_3760242_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 398.0
WH2_k127_3777468_0 Domain of Unknown Function (DUF748) - - - 8.447e-228 725.0
WH2_k127_3777468_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 573.0
WH2_k127_3777468_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 529.0
WH2_k127_3777468_3 - - - - 0.00000002971 64.0
WH2_k127_3778857_0 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 535.0
WH2_k127_3778857_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000005696 148.0
WH2_k127_3857015_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000002604 246.0
WH2_k127_3857015_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000001033 201.0
WH2_k127_3857015_2 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.0000000000000000000000001686 110.0
WH2_k127_386634_0 Putative rRNA methylase - - - 0.00000000000000000000000000000000000000000000000001608 184.0
WH2_k127_386634_1 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000001266 170.0
WH2_k127_386634_2 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000002627 169.0
WH2_k127_386634_3 PFAM ABC transporter related K06861 - - 0.000000000000000000000000000000000000000005619 157.0
WH2_k127_386634_4 Lipopolysaccharide-assembly, LptC-related - - - 0.000000000000000000000000007163 117.0
WH2_k127_3888990_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 1810.0
WH2_k127_3912509_0 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 418.0
WH2_k127_3912509_1 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 354.0
WH2_k127_3912509_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000009836 59.0
WH2_k127_3919723_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 9.247e-216 676.0
WH2_k127_3919723_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000000000000001979 256.0
WH2_k127_3919723_2 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000000000000000000000000000000004529 208.0
WH2_k127_3922231_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 601.0
WH2_k127_3922231_1 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000001135 167.0
WH2_k127_3922231_2 - - - - 0.000000000000000000000000000000000006185 143.0
WH2_k127_3935607_0 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 286.0
WH2_k127_3935607_1 Sensor histidine kinase, HAMP and PAS domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000193 228.0
WH2_k127_3956913_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 3.139e-266 834.0
WH2_k127_3956913_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000001958 191.0
WH2_k127_3956913_2 Essential cell division protein - - - 0.0000000000000000000000000000000000003731 145.0
WH2_k127_396200_0 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 526.0
WH2_k127_396200_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009557 294.0
WH2_k127_396200_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000004869 119.0
WH2_k127_3965814_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 370.0
WH2_k127_3965814_1 protein maturation K07400,K13628 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - 0.0000000001027 63.0
WH2_k127_3965814_3 protein maturation K07400,K13628 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - 0.000002057 49.0
WH2_k127_3968068_0 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005692 282.0
WH2_k127_3968068_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000236 257.0
WH2_k127_3968068_2 - - - - 0.000000000000000000000000000000000000000000003389 175.0
WH2_k127_3976065_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 336.0
WH2_k127_3976065_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 310.0
WH2_k127_3976065_2 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000004005 179.0
WH2_k127_3985618_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005492 250.0
WH2_k127_3985618_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000001283 173.0
WH2_k127_3985618_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000009921 88.0
WH2_k127_3985618_3 - - - - 0.00000000004985 75.0
WH2_k127_3992085_0 PFAM glutamate synthase alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 426.0
WH2_k127_3992085_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000538 258.0
WH2_k127_3992085_2 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000001949 222.0
WH2_k127_3992085_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000004722 128.0
WH2_k127_3992606_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 509.0
WH2_k127_3992606_1 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 357.0
WH2_k127_3992606_2 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 347.0
WH2_k127_3992606_3 LysR substrate binding domain - - - 0.0000000000000000000000000000008587 123.0
WH2_k127_4003092_0 response regulator K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 572.0
WH2_k127_4003092_1 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 440.0
WH2_k127_4003092_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 311.0
WH2_k127_4011707_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 3.098e-214 676.0
WH2_k127_4011707_1 Radical SAM domain protein K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 606.0
WH2_k127_4075559_0 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 304.0
WH2_k127_4075559_1 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000004882 258.0
WH2_k127_4075559_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000002291 138.0
WH2_k127_4101265_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 476.0
WH2_k127_4101265_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 377.0
WH2_k127_4103836_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009469 404.0
WH2_k127_4103836_1 cysteine-tRNA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 338.0
WH2_k127_4118842_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1255.0
WH2_k127_4118842_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 346.0
WH2_k127_4118842_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000002122 82.0
WH2_k127_4121919_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 1.044e-244 759.0
WH2_k127_4121919_1 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 341.0
WH2_k127_4121919_2 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 307.0
WH2_k127_4121919_3 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000589 217.0
WH2_k127_4121919_4 SprT-like family - - - 0.000000000000000006309 88.0
WH2_k127_4137335_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 340.0
WH2_k127_4137335_1 PFAM ATP-binding region, ATPase domain protein K04757 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000001936 223.0
WH2_k127_4137335_2 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000002143 221.0
WH2_k127_4137335_3 PFAM histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000003107 166.0
WH2_k127_4137335_4 Domain of unknown function (DUF4124) - - - 0.000000000000000003955 91.0
WH2_k127_4142587_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 326.0
WH2_k127_4142587_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000005484 172.0
WH2_k127_4142587_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000003462 50.0
WH2_k127_4154891_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.39e-216 679.0
WH2_k127_4154891_1 CBS domain containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 584.0
WH2_k127_4154891_2 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 450.0
WH2_k127_4154891_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 357.0
WH2_k127_4154891_4 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 344.0
WH2_k127_4154891_5 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 273.0
WH2_k127_4154891_6 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000002253 224.0
WH2_k127_4154891_7 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000000318 186.0
WH2_k127_4154891_8 Membrane protein, UPF0016 and UPF0016 domain-containing - - - 0.000000000000000000000000000000000000000000000001455 176.0
WH2_k127_416031_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 496.0
WH2_k127_416031_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 314.0
WH2_k127_416031_2 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000003109 152.0
WH2_k127_416031_3 - - - - 0.0000000000000000000000000000000005403 136.0
WH2_k127_4175010_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 294.0
WH2_k127_4175010_1 CBS domain containing protein K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002024 276.0
WH2_k127_4180850_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 442.0
WH2_k127_4180850_1 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000126 56.0
WH2_k127_4184539_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 409.0
WH2_k127_4184539_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000004492 177.0
WH2_k127_4184539_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000021 64.0
WH2_k127_4195787_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 450.0
WH2_k127_4195787_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000001686 250.0
WH2_k127_4195787_2 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000001685 98.0
WH2_k127_419907_0 elongation factor G domain IV K02355 - - 0.0 1227.0
WH2_k127_419907_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 404.0
WH2_k127_419907_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000002288 78.0
WH2_k127_4200651_0 beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003078 271.0
WH2_k127_4200651_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000002191 167.0
WH2_k127_4200651_2 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000000000005829 124.0
WH2_k127_4208301_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.099e-221 693.0
WH2_k127_4208301_1 Amidohydrolase family K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 476.0
WH2_k127_4208301_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 426.0
WH2_k127_4208301_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 374.0
WH2_k127_4208301_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 346.0
WH2_k127_4208301_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000005438 226.0
WH2_k127_4208301_6 Gaf domain K03406 - - 0.00000000000000000000000000000002152 131.0
WH2_k127_4208301_7 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000003324 87.0
WH2_k127_4208301_8 response regulator - - - 0.00000000000005198 73.0
WH2_k127_4233131_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 1.028e-241 752.0
WH2_k127_4233131_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000019 275.0
WH2_k127_4258536_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.08e-322 991.0
WH2_k127_4262370_0 Sodium/hydrogen exchanger family K03455,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001334 260.0
WH2_k127_4262370_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000245 193.0
WH2_k127_4262370_2 - - - - 0.00000000000000000000000000000000001153 141.0
WH2_k127_4265923_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 2.82e-231 732.0
WH2_k127_4274983_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 3.592e-314 968.0
WH2_k127_4274983_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 385.0
WH2_k127_4274983_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000002945 55.0
WH2_k127_4318054_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 326.0
WH2_k127_4318054_1 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 286.0
WH2_k127_4318054_2 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000001923 171.0
WH2_k127_4359107_0 CBS domain containing protein K00974 - 2.7.7.72 2.062e-287 903.0
WH2_k127_441614_0 FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 617.0
WH2_k127_441614_1 histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001568 252.0
WH2_k127_441614_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000002149 196.0
WH2_k127_441614_3 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00007774 45.0
WH2_k127_4420864_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 366.0
WH2_k127_4420864_1 Nickel-dependent hydrogenase large subunit - - - 0.00000000000000000000000000000000000000000000726 170.0
WH2_k127_4443339_0 belongs to the CobB CobQ family K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 496.0
WH2_k127_4443339_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 344.0
WH2_k127_4443339_2 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000003896 158.0
WH2_k127_4443339_3 - - - - 0.000000006811 60.0
WH2_k127_4451850_0 Belongs to the pseudouridine synthase RluA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 391.0
WH2_k127_4451850_1 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000001357 246.0
WH2_k127_4451850_2 CHASE3 domain - - - 0.0000000007993 60.0
WH2_k127_4455772_0 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 402.0
WH2_k127_4455772_1 Transcriptional regulatory protein, C terminal K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003875 273.0
WH2_k127_4531219_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 515.0
WH2_k127_4531219_1 Nucleotidyltransferase domain - - - 0.000000000000000000000000000002953 123.0
WH2_k127_4531219_2 HEPN domain - - - 0.000000000000000000000000000077 120.0
WH2_k127_4601913_0 Fatty acid cis/trans isomerase (CTI) - - - 0.0 1242.0
WH2_k127_4601913_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002955 238.0
WH2_k127_4601913_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000007899 157.0
WH2_k127_4601913_3 diguanylate cyclase K21088 - 2.7.7.65 0.00000000009075 69.0
WH2_k127_462080_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 370.0
WH2_k127_462080_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005185 272.0
WH2_k127_4642114_0 Transport of potassium into the cell K03549 - - 0.0 1015.0
WH2_k127_4642114_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 601.0
WH2_k127_4655006_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 301.0
WH2_k127_4655006_1 3' exoribonuclease, RNase T-like K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 287.0
WH2_k127_4657639_0 General secretory system II protein E domain protein - - - 6.496e-196 630.0
WH2_k127_4657639_1 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000002844 154.0
WH2_k127_4705340_0 PFAM Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 382.0
WH2_k127_4705340_1 YtxH-like protein - - - 0.0000001493 54.0
WH2_k127_4705340_2 metal-dependent phosphohydrolase HD sub domain K07814 - - 0.0002896 45.0
WH2_k127_4727288_0 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000122 252.0
WH2_k127_4727288_1 - - - - 0.000000000000000000000000000000008455 133.0
WH2_k127_4727288_2 MlaD protein K06192 - - 0.00000000000000000000000000000003027 133.0
WH2_k127_4727288_3 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000002964 121.0
WH2_k127_4738032_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.094e-234 730.0
WH2_k127_4738032_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 369.0
WH2_k127_4738032_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000001004 190.0
WH2_k127_4769059_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000002159 246.0
WH2_k127_4769059_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000003507 225.0
WH2_k127_4769059_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000007594 200.0
WH2_k127_4781778_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 2.273e-236 739.0
WH2_k127_4781778_1 NADH dehydrogenase - - - 0.0000000000000000000000000000001395 124.0
WH2_k127_4859508_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 8.314e-240 745.0
WH2_k127_4859508_1 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 365.0
WH2_k127_4859508_2 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000174 266.0
WH2_k127_4859508_3 PFAM Rieske 2Fe-2S K00363 - 1.7.1.15 0.000000000000000000000000000000000002677 139.0
WH2_k127_4867156_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986,K15342 - 2.7.7.49 7.252e-211 663.0
WH2_k127_4867156_1 - - - - 0.0000000000000000000000000001637 115.0
WH2_k127_4867156_2 PFAM ThiJ PfpI domain protein - - - 0.000000000001872 67.0
WH2_k127_4872222_0 Transposase domain (DUF772) - - - 3.096e-204 646.0
WH2_k127_4872222_1 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 462.0
WH2_k127_4872222_2 Protein of unknown function (DUF1847) - - - 0.00000000001881 66.0
WH2_k127_4886118_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 398.0
WH2_k127_4886118_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006407 274.0
WH2_k127_4886118_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000002142 74.0
WH2_k127_4893014_0 S1 domain K00243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 446.0
WH2_k127_4893014_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 429.0
WH2_k127_4893014_2 DbpA RNA binding domain K05591 - 3.6.4.13 0.0000000000000000000000000000003113 123.0
WH2_k127_489327_0 4Fe-4S dicluster domain - - - 6.392e-225 702.0
WH2_k127_489327_1 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 546.0
WH2_k127_489327_2 4fe-4S ferredoxin, iron-sulfur binding domain protein K19516 - - 0.000000000000000000000000000000000000000000000000000000000000000000007781 238.0
WH2_k127_489327_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000002773 146.0
WH2_k127_4904250_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1239.0
WH2_k127_4904250_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1070.0
WH2_k127_4904250_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005568 271.0
WH2_k127_4904250_3 With S4 and S5 plays an important role in translational accuracy K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001242 242.0
WH2_k127_4938813_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003394 285.0
WH2_k127_4938813_1 response regulator - - - 0.0000000000000000000000000000000000000000000000001309 182.0
WH2_k127_4940777_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.628e-310 956.0
WH2_k127_4940777_1 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 298.0
WH2_k127_4940777_2 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000004881 206.0
WH2_k127_4940777_3 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000000000000000000000005773 187.0
WH2_k127_4940777_4 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000002696 165.0
WH2_k127_4945212_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 450.0
WH2_k127_4945212_1 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 302.0
WH2_k127_4945212_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002489 257.0
WH2_k127_4945212_3 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000001046 209.0
WH2_k127_4945212_4 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000002961 111.0
WH2_k127_4973579_0 PFAM ABC transporter related - - - 5e-324 996.0
WH2_k127_4973579_1 DTW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 291.0
WH2_k127_4973579_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000003032 176.0
WH2_k127_4973579_3 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000000003212 141.0
WH2_k127_4977582_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007814 279.0
WH2_k127_4977582_1 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000002446 118.0
WH2_k127_4977582_2 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000001723 109.0
WH2_k127_4980757_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 3.098e-214 676.0
WH2_k127_5007108_0 Cobalamin (Vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 407.0
WH2_k127_5007108_1 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001121 289.0
WH2_k127_5007108_2 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001665 280.0
WH2_k127_5015292_0 Belongs to the GARS family K01945 - 6.3.4.13 3.029e-217 681.0
WH2_k127_5015292_1 PFAM ResB family protein K07399 - - 1.635e-194 616.0
WH2_k127_5015292_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000004642 259.0
WH2_k127_5015292_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000003155 238.0
WH2_k127_5015292_5 PFAM cytochrome c assembly protein - - - 0.00000000000006231 74.0
WH2_k127_5042739_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 353.0
WH2_k127_5042739_1 - - - - 0.00000000000000000000000000000000000000000000000601 172.0
WH2_k127_5042739_2 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.0000000000000000000000000006621 115.0
WH2_k127_5042739_4 Uncharacterised protein family (UPF0270) K07019,K09898 - - 0.00000000000000000007672 94.0
WH2_k127_5050865_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1124.0
WH2_k127_5050865_1 TIGRFAM MATE efflux family protein K03327 - - 7.88e-199 626.0
WH2_k127_5050865_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000002377 151.0
WH2_k127_5050865_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000001255 112.0
WH2_k127_513732_0 Isocitrate dehydrogenase NADP-dependent, monomeric type K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 475.0
WH2_k127_513732_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 424.0
WH2_k127_513732_2 LysM domain - - - 0.00000000000000000000000000000000000000005927 159.0
WH2_k127_5144689_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002729 278.0
WH2_k127_5144689_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000004745 205.0
WH2_k127_5144689_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000004971 202.0
WH2_k127_5153672_0 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 408.0
WH2_k127_5153672_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002062 251.0
WH2_k127_5153672_2 Pfam:Methyltransf_26 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000001737 156.0
WH2_k127_5156982_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 5.938e-227 703.0
WH2_k127_5156982_1 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000146 274.0
WH2_k127_5156982_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000005932 79.0
WH2_k127_5166733_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 1.105e-197 630.0
WH2_k127_5170841_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 6.396e-201 627.0
WH2_k127_5170841_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 332.0
WH2_k127_5170841_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000006646 147.0
WH2_k127_5170841_3 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.0000000000000000000000000002685 113.0
WH2_k127_5178207_0 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 579.0
WH2_k127_5178207_1 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 339.0
WH2_k127_5178207_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 296.0
WH2_k127_5178207_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007971 280.0
WH2_k127_5178207_5 ABC transporter K02065 - - 0.0000000000000000000005891 98.0
WH2_k127_5178207_7 domain protein - - - 0.0008386 48.0
WH2_k127_5201654_0 Domain of unknown function (DUF4105) - - - 1.669e-231 733.0
WH2_k127_5201654_1 Protein of unknown function (DUF3015) - - - 0.0000000000000000000000000000000000000000000000000000000000001291 215.0
WH2_k127_5201654_2 PFAM alpha amylase catalytic region - - - 0.000000000000000000000001053 111.0
WH2_k127_5201654_3 Glutaredoxin - - - 0.00000000008988 68.0
WH2_k127_5206844_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008951 267.0
WH2_k127_5206844_1 TIGRFAM addiction module antidote protein - - - 0.000000000000000000000000000000000000000000000001905 175.0
WH2_k127_5206844_2 TIGRFAM Addiction module killer protein - - - 0.000000000000000000000000000000000000000003275 156.0
WH2_k127_5206844_3 ATPases associated with a variety of cellular activities - - - 0.000000000000000000002595 95.0
WH2_k127_5209965_0 COG NOG09493 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 465.0
WH2_k127_5209965_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 428.0
WH2_k127_52114_0 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 387.0
WH2_k127_52114_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 348.0
WH2_k127_52114_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000006365 201.0
WH2_k127_5223610_0 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 589.0
WH2_k127_5223610_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000002256 217.0
WH2_k127_5223610_2 BRO family, N-terminal domain - - - 0.0000000000000000002199 95.0
WH2_k127_5223610_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000006489 53.0
WH2_k127_5307856_0 PFAM peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 420.0
WH2_k127_5307856_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000002298 190.0
WH2_k127_530853_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 511.0
WH2_k127_530853_1 Domains LysM, LysM, NLPC_P60 K19223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 387.0
WH2_k127_530853_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000003387 64.0
WH2_k127_5316505_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 462.0
WH2_k127_5316505_1 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 359.0
WH2_k127_5316505_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 341.0
WH2_k127_5358312_0 malic protein domain protein K00029 - 1.1.1.40 3.74e-309 953.0
WH2_k127_5358312_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 325.0
WH2_k127_5358312_2 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000009305 207.0
WH2_k127_5358312_3 energy transducer activity K03646,K03832 - - 0.00000000000000000000000000009767 126.0
WH2_k127_5366851_0 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 413.0
WH2_k127_5366851_1 PFAM ThiJ PfpI domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 314.0
WH2_k127_5366851_2 - - - - 0.0000000000000000000000000000000000000000000000000002485 191.0
WH2_k127_5366851_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000001466 53.0
WH2_k127_5377419_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 4.091e-314 967.0
WH2_k127_5377419_1 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000008273 192.0
WH2_k127_5388547_0 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001392 281.0
WH2_k127_5388547_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001339 237.0
WH2_k127_5388547_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000003878 194.0
WH2_k127_5388547_3 - - - - 0.000000000000000000000000000009833 120.0
WH2_k127_5388547_4 Sulphur transport K07112 - - 0.000000000001361 67.0
WH2_k127_5441022_0 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 4.86e-226 704.0
WH2_k127_5441022_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 522.0
WH2_k127_5441022_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000284 246.0
WH2_k127_5441022_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000009627 188.0
WH2_k127_5441022_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000003847 141.0
WH2_k127_5450160_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 429.0
WH2_k127_5450160_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000008236 229.0
WH2_k127_5450160_2 tRNA processing K06864 - - 0.0000000000000000000000003577 108.0
WH2_k127_5478685_0 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 437.0
WH2_k127_5478685_1 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 298.0
WH2_k127_5478685_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000003158 234.0
WH2_k127_5478685_3 Peptidase dimerisation domain K12941 - - 0.0000000000000000000000000000000000000000007314 161.0
WH2_k127_5478685_4 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000005796 131.0
WH2_k127_5482928_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 523.0
WH2_k127_5482928_1 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000003497 248.0
WH2_k127_5491054_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 588.0
WH2_k127_5491054_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 569.0
WH2_k127_5491054_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 396.0
WH2_k127_5491054_3 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000001257 205.0
WH2_k127_5491054_4 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.00000000000000000000000000000000000000000000000002606 185.0
WH2_k127_5491054_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000001013 175.0
WH2_k127_5526690_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 8.402e-279 873.0
WH2_k127_5526690_1 regulator, PATAN and FRGAF domain-containing - - - 7.609e-214 680.0
WH2_k127_5526690_2 Ferrous iron transport protein B K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 541.0
WH2_k127_5526690_3 Pfam:Arch_ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 424.0
WH2_k127_5526690_4 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000001714 223.0
WH2_k127_5526690_5 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000001062 208.0
WH2_k127_5526690_6 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000001815 207.0
WH2_k127_5526690_7 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000000000003539 203.0
WH2_k127_5526690_8 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000000000000000006226 168.0
WH2_k127_5526690_9 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000008467 110.0
WH2_k127_5527567_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.095e-280 874.0
WH2_k127_5527567_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 389.0
WH2_k127_5527567_2 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001791 244.0
WH2_k127_5527567_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000001916 203.0
WH2_k127_5527567_4 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000000000000481 160.0
WH2_k127_5547316_0 heat shock protein DnaJ domain protein K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 444.0
WH2_k127_5547316_1 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 353.0
WH2_k127_5547316_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 320.0
WH2_k127_5547316_3 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000008786 191.0
WH2_k127_5547316_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000002664 118.0
WH2_k127_5558832_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 472.0
WH2_k127_5558832_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 316.0
WH2_k127_5558832_2 CRS1_YhbY K07574 - - 0.0000000000000000000000000000000000003174 142.0
WH2_k127_5558832_3 electron transfer activity K05337 - - 0.0000000000000002287 80.0
WH2_k127_5581383_0 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 1.424e-257 802.0
WH2_k127_5581383_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 606.0
WH2_k127_5581383_2 PFAM transport-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 371.0
WH2_k127_5581383_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 323.0
WH2_k127_5581383_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000001522 238.0
WH2_k127_5581383_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000003174 174.0
WH2_k127_5581383_6 MgtC family K07507 - - 0.000000000000000000000000000000003545 131.0
WH2_k127_5588271_0 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 2.166e-260 805.0
WH2_k127_5588271_1 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 413.0
WH2_k127_5588271_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000007336 198.0
WH2_k127_5588271_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000001053 198.0
WH2_k127_5588271_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000008721 195.0
WH2_k127_5588271_5 PFAM outer membrane efflux protein - - - 0.000000000000000000000000000000000000001859 157.0
WH2_k127_5588271_6 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000008374 145.0
WH2_k127_5588271_7 Tetratricopeptide repeat - - - 0.000000000000002667 82.0
WH2_k127_5588949_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 338.0
WH2_k127_5588949_1 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002694 286.0
WH2_k127_5588949_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000004432 136.0
WH2_k127_5594459_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 507.0
WH2_k127_5594459_1 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 322.0
WH2_k127_5603113_0 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 529.0
WH2_k127_5603113_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 365.0
WH2_k127_5603113_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000002312 177.0
WH2_k127_5603113_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000002938 138.0
WH2_k127_5611173_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 9.544e-216 673.0
WH2_k127_5611173_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 489.0
WH2_k127_5611173_2 PFAM ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 395.0
WH2_k127_5611173_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003046 244.0
WH2_k127_5611173_4 Bacterial protein of unknown function (DUF948) - - - 0.00000000000000000000000000000001153 131.0
WH2_k127_5611173_5 YtxH-like protein - - - 0.0000000000000000000000000000008722 124.0
WH2_k127_5625596_0 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 330.0
WH2_k127_5625596_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000009252 243.0
WH2_k127_5625596_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000001001 172.0
WH2_k127_5625596_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000000000000000000006227 167.0
WH2_k127_5625596_4 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000002823 68.0
WH2_k127_5663910_0 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 535.0
WH2_k127_5663910_1 Transcription elongation factor, GreA/GreB, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000004589 217.0
WH2_k127_5663910_2 - - - - 0.00000000000004339 75.0
WH2_k127_5663910_3 Acetyltransferase (GNAT) domain K03824 - - 0.000000000000201 70.0
WH2_k127_5672179_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000002142 195.0
WH2_k127_5672179_1 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000001391 173.0
WH2_k127_5709670_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 3.293e-289 891.0
WH2_k127_5709670_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 587.0
WH2_k127_5709670_2 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 554.0
WH2_k127_5709670_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 439.0
WH2_k127_5709670_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 383.0
WH2_k127_5709670_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 314.0
WH2_k127_5709670_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007169 283.0
WH2_k127_5750937_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.964e-254 795.0
WH2_k127_5750937_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 334.0
WH2_k127_5768245_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 9.161e-230 716.0
WH2_k127_5777635_0 PFAM Dinitrogenase reductase ADP-ribosyltransferase K05951 - 2.4.2.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 381.0
WH2_k127_5777635_1 PIN domain - - - 0.000000000000000000000000000000000000000000000000000000003545 201.0
WH2_k127_5777635_3 Transcriptional regulator - - - 0.000000000000000001025 87.0
WH2_k127_5786153_0 PFAM peptidase M16 domain protein - - - 1.137e-208 661.0
WH2_k127_5786153_1 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002036 273.0
WH2_k127_5786153_2 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000009109 176.0
WH2_k127_5793024_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 1.26e-206 650.0
WH2_k127_5793024_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 301.0
WH2_k127_5793024_2 PFAM Class I peptide chain release factor - - - 0.0000000000000000000000000000000000004194 144.0
WH2_k127_5813401_0 Motility response receiver histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 458.0
WH2_k127_5813401_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000001131 138.0
WH2_k127_5813401_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000002262 55.0
WH2_k127_5854589_0 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 416.0
WH2_k127_5872197_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 460.0
WH2_k127_5872197_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 389.0
WH2_k127_5872197_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000008215 101.0
WH2_k127_5872197_3 Methyltransferase domain - - - 0.000000000000000000001705 103.0
WH2_k127_5901763_0 TIGRFAM ammonium transporter K03320 - - 9.434e-226 702.0
WH2_k127_5901763_1 Nitrogen fixation transcript antitermination sensor histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001244 273.0
WH2_k127_5901763_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000001471 190.0
WH2_k127_5905424_0 Pfam:UPF0118 K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 379.0
WH2_k127_5905424_1 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 296.0
WH2_k127_5905424_2 PFAM penicillin-binding protein transpeptidase - - - 0.00000000000000000000000000000000000000000000000000000000005134 207.0
WH2_k127_5905424_3 Uncharacterised protein family (UPF0158) - - - 0.000000000000000000000000000000000000000000005796 168.0
WH2_k127_5905424_4 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000001584 109.0
WH2_k127_5905424_5 permease K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000121 76.0
WH2_k127_599129_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 1.965e-251 786.0
WH2_k127_599129_1 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 324.0
WH2_k127_5992297_0 sensor histidine kinase response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 429.0
WH2_k127_5994292_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 556.0
WH2_k127_5994292_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 500.0
WH2_k127_5994292_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000008888 122.0
WH2_k127_5996129_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 438.0
WH2_k127_5996129_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006495 261.0
WH2_k127_6002390_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 3.083e-228 709.0
WH2_k127_6002390_1 PFAM thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 526.0
WH2_k127_6002390_2 Glycine zipper - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 325.0
WH2_k127_6002390_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 308.0
WH2_k127_6002390_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004962 276.0
WH2_k127_6002390_5 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000000000000000005234 125.0
WH2_k127_6017412_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 409.0
WH2_k127_6017412_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002005 246.0
WH2_k127_6029921_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 4.217e-199 625.0
WH2_k127_6029921_1 GGDEF domain K03413 - - 0.000000000000000000000000000000000000000000000004201 178.0
WH2_k127_6051552_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 6.12e-226 713.0
WH2_k127_6051552_1 PFAM Class II aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 480.0
WH2_k127_6051552_2 Protein of unknown function, DUF481 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 413.0
WH2_k127_6051552_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000003471 216.0
WH2_k127_6051552_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000001992 168.0
WH2_k127_6078228_0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 326.0
WH2_k127_6078228_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 291.0
WH2_k127_6078228_2 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000006907 135.0
WH2_k127_6118031_0 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 2.619e-292 906.0
WH2_k127_6118031_1 Domains REC, sigma54 interaction, HTH8 - - - 8.398e-233 732.0
WH2_k127_6118031_3 PFAM diacylglycerol kinase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002071 271.0
WH2_k127_6118031_6 Cytidylate kinase-like family - - - 0.00000462 48.0
WH2_k127_6118133_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.7.99.1 1.309e-219 683.0
WH2_k127_6118133_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 550.0
WH2_k127_6121793_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 1.096e-200 636.0
WH2_k127_6121793_1 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.000000000000000000000000001267 113.0
WH2_k127_6121793_3 CRISPR-associated endoribonuclease Cas6 - - - 0.000000000000007002 81.0
WH2_k127_6140224_0 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 371.0
WH2_k127_6140224_1 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 327.0
WH2_k127_6140224_2 Sodium:sulfate symporter transmembrane region K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007346 255.0
WH2_k127_6152314_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 1.012e-264 839.0
WH2_k127_6152314_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 531.0
WH2_k127_6152314_10 Cytochrome oxidase maturation protein - - - 0.0000000000007549 70.0
WH2_k127_6152314_2 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 512.0
WH2_k127_6152314_3 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 458.0
WH2_k127_6152314_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 385.0
WH2_k127_6152314_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000001367 217.0
WH2_k127_6152314_6 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000009496 203.0
WH2_k127_6152314_7 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.0000000000000000000000003116 108.0
WH2_k127_6152314_8 PAS domain - - - 0.000000000000000000000269 102.0
WH2_k127_6152314_9 - - - - 0.000000000000000009535 85.0
WH2_k127_6178163_0 Baseplate assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 526.0
WH2_k127_6178163_1 homolog of phage Mu protein gp47 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 396.0
WH2_k127_6178163_2 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009165 248.0
WH2_k127_6178163_3 Late control gene D protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004625 228.0
WH2_k127_6192536_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.694e-239 749.0
WH2_k127_6192536_1 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000236 204.0
WH2_k127_619321_0 ABC transporter transmembrane region K06147,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 395.0
WH2_k127_619321_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 375.0
WH2_k127_619321_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001713 267.0
WH2_k127_6204563_0 Domain of unknown function (DUF2088) - - - 3.201e-206 650.0
WH2_k127_6204563_1 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000005796 190.0
WH2_k127_6204563_2 Ferric uptake regulator family K03711,K09825 - - 0.0000000000000000000000000001977 120.0
WH2_k127_6204563_3 Rubrerythrin - - - 0.000000000000000157 79.0
WH2_k127_6228446_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 527.0
WH2_k127_6228446_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 458.0
WH2_k127_6228446_2 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 422.0
WH2_k127_6228446_3 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000000000000000000479 201.0
WH2_k127_6228446_4 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000002551 103.0
WH2_k127_626305_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 8.695e-309 951.0
WH2_k127_626305_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000001978 111.0
WH2_k127_6271552_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 484.0
WH2_k127_6271552_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001884 251.0
WH2_k127_6271552_2 Pfam:DUF162 - - - 0.00007901 46.0
WH2_k127_6271613_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 4.608e-272 841.0
WH2_k127_6271613_1 cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 460.0
WH2_k127_6271613_2 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000000000000000000000000004428 204.0
WH2_k127_6271613_3 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000008864 134.0
WH2_k127_6271613_4 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.000000000000000000000000000002837 125.0
WH2_k127_6271613_5 - - - - 0.00000000000000009952 87.0
WH2_k127_6289167_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 406.0
WH2_k127_6289167_1 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000002784 195.0
WH2_k127_6289167_2 Rubrerythrin - - - 0.000000000000000000000000000000000000000000001047 167.0
WH2_k127_6314297_0 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 503.0
WH2_k127_6314297_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 434.0
WH2_k127_6314297_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000007532 243.0
WH2_k127_6314297_3 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000001385 230.0
WH2_k127_6314297_4 PFAM asparagine synthase K06864 - - 0.000000000000000000000000000000000000000237 153.0
WH2_k127_6314297_5 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000006063 81.0
WH2_k127_6317968_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 539.0
WH2_k127_6317968_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 313.0
WH2_k127_6318998_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 6.242e-199 641.0
WH2_k127_6318998_1 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001733 235.0
WH2_k127_6327654_0 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000001019 212.0
WH2_k127_6327654_1 - - - - 0.00000000009358 66.0
WH2_k127_6327654_2 - - - - 0.000008595 55.0
WH2_k127_6327654_3 Heavy-metal resistance K07803 - - 0.00004878 52.0
WH2_k127_6345382_0 Uncharacterised protein family (UPF0182) K09118 - - 1.904e-306 943.0
WH2_k127_635947_0 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 414.0
WH2_k127_635947_1 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001513 250.0
WH2_k127_6375114_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 472.0
WH2_k127_6375114_1 Ferritin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 319.0
WH2_k127_6375114_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000133 283.0
WH2_k127_6375114_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0008703 43.0
WH2_k127_6414820_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 577.0
WH2_k127_6414820_1 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000002503 267.0
WH2_k127_6414820_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000001215 214.0
WH2_k127_6458881_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 519.0
WH2_k127_6458881_1 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000001744 145.0
WH2_k127_6495740_0 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 389.0
WH2_k127_6495740_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739,K01760 - 2.5.1.48,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 359.0
WH2_k127_6495740_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 326.0
WH2_k127_6495740_3 Uncharacterized small protein (DUF2292) - - - 0.0000004439 56.0
WH2_k127_651265_0 PFAM transposase, IS4 family protein - - - 3.066e-217 676.0
WH2_k127_651265_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 511.0
WH2_k127_651265_2 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000001623 194.0
WH2_k127_6524228_0 TRAP dicarboxylate transporter, DctM subunit K11690 - - 1.771e-201 636.0
WH2_k127_6524228_1 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 463.0
WH2_k127_6524228_2 CBS domain containing protein K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 455.0
WH2_k127_6524228_3 Two component transcriptional regulator, winged helix family K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 317.0
WH2_k127_6524228_4 Transcriptional regulator IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 287.0
WH2_k127_6524228_5 PFAM Tripartite ATP-independent periplasmic transporter DctQ component K11689 GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015556,GO:0015711,GO:0015740,GO:0015849,GO:0022857,GO:0034220,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000001245 147.0
WH2_k127_6524228_6 membrane - - - 0.00000000000000000000000000002454 119.0
WH2_k127_6524228_7 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000007341 54.0
WH2_k127_6541124_0 AcrB/AcrD/AcrF family K03296 - - 1.452e-319 988.0
WH2_k127_6541124_1 Protein of unknown function (DUF2860) - - - 0.0000000004463 62.0
WH2_k127_6543044_0 PFAM alpha amylase, catalytic region K01176 - 3.2.1.1 1.329e-216 679.0
WH2_k127_6543044_1 cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 500.0
WH2_k127_6543044_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 455.0
WH2_k127_6543044_3 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000943 259.0
WH2_k127_6566439_0 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 596.0
WH2_k127_6566439_1 PFAM aminotransferase, class I and II K11358 - 2.6.1.1 0.00000000000000000000000000000000000000003828 152.0
WH2_k127_6586398_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009751 305.0
WH2_k127_6586398_1 Prokaryotic N-terminal methylation motif K08084 - - 0.0000000000000000000000000003399 119.0
WH2_k127_6586398_2 transposition, RNA-mediated - - - 0.00001255 58.0
WH2_k127_6602303_0 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 1.158e-223 706.0
WH2_k127_6602303_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 502.0
WH2_k127_6602303_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 496.0
WH2_k127_6602303_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 328.0
WH2_k127_6602303_4 TIGRFAM D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000001314 239.0
WH2_k127_6602303_5 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000004646 226.0
WH2_k127_6602303_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000008406 108.0
WH2_k127_6602303_7 rod shape-determining protein MreD K03571 - - 0.000000000000000000002405 101.0
WH2_k127_6605672_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 507.0
WH2_k127_6605672_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 417.0
WH2_k127_6605672_2 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006166 281.0
WH2_k127_6612233_0 Bacterial protein of unknown function (DUF853) K06915 - - 6.872e-256 795.0
WH2_k127_6629703_0 phosphoenolpyruvate-protein phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 374.0
WH2_k127_6629703_1 histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 376.0
WH2_k127_6629703_2 Universal stress protein K06149 - - 0.00000000000000000000000000000000000000000000000000000000000001359 219.0
WH2_k127_6629703_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000002267 211.0
WH2_k127_6629703_4 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000000000000000000000001243 181.0
WH2_k127_6643476_0 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 358.0
WH2_k127_6643476_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 315.0
WH2_k127_6643476_2 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 294.0
WH2_k127_6643476_3 - K02009 - - 0.000000000000000000000000000000001572 132.0
WH2_k127_6647701_0 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007174 238.0
WH2_k127_6647701_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000001255 132.0
WH2_k127_66522_0 4Fe-4S ferredoxin iron-sulfur binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003775 284.0
WH2_k127_6679820_0 Metal-dependent phosphohydrolase K07037 - - 1.346e-283 892.0
WH2_k127_6679820_1 Oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 354.0
WH2_k127_6679820_2 - - - - 0.0000000000000000000000000000000000000000000000000005461 186.0
WH2_k127_6679820_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000001618 82.0
WH2_k127_6685724_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001194 273.0
WH2_k127_6685724_1 SMART Elongator protein 3 MiaB NifB K07139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001649 258.0
WH2_k127_6685724_2 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000001339 188.0
WH2_k127_6700480_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 590.0
WH2_k127_6700480_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000001158 192.0
WH2_k127_6700480_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000001439 157.0
WH2_k127_6762501_0 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 329.0
WH2_k127_6762501_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000002135 243.0
WH2_k127_6762501_2 beta-lactamase activity K07126 - - 0.000000000000000000000000000000000000117 149.0
WH2_k127_678231_0 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 336.0
WH2_k127_678231_1 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 332.0
WH2_k127_678231_2 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007604 273.0
WH2_k127_678231_4 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000002943 53.0
WH2_k127_678231_5 PFAM CMP dCMP deaminase zinc-binding K01485 - 3.5.4.1 0.0000184 48.0
WH2_k127_678231_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00004968 51.0
WH2_k127_6785327_0 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 544.0
WH2_k127_6785327_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 342.0
WH2_k127_6785327_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 292.0
WH2_k127_6785327_3 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004596 261.0
WH2_k127_6785327_4 DNA recombination K09760 - - 0.0000000000000000000000000000000000000000000000001021 179.0
WH2_k127_6832230_0 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001963 208.0
WH2_k127_6832230_1 protein conserved in bacteria - - - 0.000000000000000001165 97.0
WH2_k127_6894722_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 9.469e-224 701.0
WH2_k127_6894722_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 538.0
WH2_k127_6894722_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 396.0
WH2_k127_6894722_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 389.0
WH2_k127_6898632_0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000001192 199.0
WH2_k127_6898632_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000173 190.0
WH2_k127_6898632_2 YHS domain - - - 0.00000000000000000000511 100.0
WH2_k127_6898632_3 peptidyl-tyrosine sulfation - - - 0.000000001268 64.0
WH2_k127_6911198_0 Cytochrome c bacterial - - - 2.233e-256 797.0
WH2_k127_6911198_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 587.0
WH2_k127_6911198_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 497.0
WH2_k127_6911198_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 324.0
WH2_k127_6911198_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000004414 156.0
WH2_k127_6911198_5 Ion transport 2 domain protein K10716 - - 0.0000000000000000001648 89.0
WH2_k127_6918156_0 PFAM biotin lipoyl attachment domain-containing protein - - - 0.0 1653.0
WH2_k127_693865_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1175.0
WH2_k127_693865_1 beta-lactamase activity K07126 - - 0.000000000000000000000000000000000000000000000000945 183.0
WH2_k127_6989279_0 PFAM UvrD REP helicase K03656,K03657 - 3.6.4.12 2.015e-229 721.0
WH2_k127_6989279_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003572 281.0
WH2_k127_7015905_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 376.0
WH2_k127_7015905_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 299.0
WH2_k127_7029643_0 denitrification pathway - - - 3.834e-284 879.0
WH2_k127_7029643_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 516.0
WH2_k127_7029643_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000008695 107.0
WH2_k127_7042295_0 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007815 259.0
WH2_k127_7042295_1 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002154 224.0
WH2_k127_7054732_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.5e-323 998.0
WH2_k127_7054732_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000003914 158.0
WH2_k127_7067101_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 590.0
WH2_k127_7067101_1 PFAM type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 574.0
WH2_k127_7067101_2 Sensor histidine kinase, PAS and GAF domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 544.0
WH2_k127_7067101_3 Competence-damaged protein K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000006371 128.0
WH2_k127_7067101_4 Modulates RecA activity K03565 - - 0.0001112 51.0
WH2_k127_7098486_0 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 7.995e-205 643.0
WH2_k127_7098486_1 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 344.0
WH2_k127_7098486_2 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 334.0
WH2_k127_7100088_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 329.0
WH2_k127_7100088_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001455 233.0
WH2_k127_7100088_2 Plasmid maintenance system killer K07334 - - 0.0000000000001105 72.0
WH2_k127_7126010_0 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 597.0
WH2_k127_7126010_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739,K01760 - 2.5.1.48,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 338.0
WH2_k127_7126010_2 Nitrogen fixation transcript antitermination response regulator, ANTAR domain-containing K22010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009277 267.0
WH2_k127_71487_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 494.0
WH2_k127_71487_1 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.000000000000000000000000000000000000000000000003294 175.0
WH2_k127_71487_2 PFAM ATP-binding region, ATPase domain protein K04757 - 2.7.11.1 0.000000000000000000000000000000000000000000004898 166.0
WH2_k127_7202668_0 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 442.0
WH2_k127_7202668_1 PFAM periplasmic solute binding protein K09815 - - 0.000000003532 62.0
WH2_k127_7219847_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1765.0
WH2_k127_726453_0 histidine kinase, HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 405.0
WH2_k127_726453_1 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 393.0
WH2_k127_726453_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000002613 203.0
WH2_k127_7266398_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.424e-219 682.0
WH2_k127_7266398_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000007115 141.0
WH2_k127_7266398_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000005131 113.0
WH2_k127_7284795_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1125.0
WH2_k127_7284795_1 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 530.0
WH2_k127_7292563_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 516.0
WH2_k127_7292563_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 394.0
WH2_k127_7306300_0 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 426.0
WH2_k127_7306300_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000007358 259.0
WH2_k127_7306300_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000000000000000000001871 152.0
WH2_k127_7306300_3 Protein of unknown function (DUF2905) - - - 0.00000000000000000000000004206 109.0
WH2_k127_7306300_4 Protein conserved in bacteria - - - 0.000000000000000000000000204 109.0
WH2_k127_7306300_5 - - - - 0.00000000000000000000007767 100.0
WH2_k127_7306300_6 ABC1 family K03688 - - 0.0000000000000001509 80.0
WH2_k127_7310713_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 431.0
WH2_k127_7310713_1 TrkA-N domain K03499 - - 0.00000000000000000000000000001852 119.0
WH2_k127_732654_0 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000005382 218.0
WH2_k127_732654_1 Predicted membrane protein (DUF2232) - - - 0.000000000000000000000000000000000000000000000000002377 194.0
WH2_k127_732654_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000002366 181.0
WH2_k127_732654_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001306 158.0
WH2_k127_732654_4 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000004401 149.0
WH2_k127_732654_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000006853 133.0
WH2_k127_7342432_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 359.0
WH2_k127_7353572_0 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 395.0
WH2_k127_7353572_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000128 246.0
WH2_k127_7353572_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000000000000000000000001525 201.0
WH2_k127_7353572_3 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.0000000000000000000000000000000000000000000000007166 178.0
WH2_k127_7379885_0 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 344.0
WH2_k127_7379885_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000001325 114.0
WH2_k127_7388745_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 6.775e-263 812.0
WH2_k127_7388745_1 Sensor histidine kinase, HAMP and PAS domain-containing - - - 3.828e-220 703.0
WH2_k127_7388745_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 507.0
WH2_k127_7388745_3 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 354.0
WH2_k127_7388745_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000438 267.0
WH2_k127_7399279_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 389.0
WH2_k127_7399279_1 HMGL-like K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000001224 214.0
WH2_k127_7399279_2 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 0.00000000000001089 74.0
WH2_k127_7406668_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 579.0
WH2_k127_7406668_1 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 443.0
WH2_k127_7406668_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000003006 183.0
WH2_k127_7406668_3 Dihydrofolate reductase K00287,K18589 - 1.5.1.3 0.0000000000000000000000000000000000000000000000004268 181.0
WH2_k127_7406668_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000001009 100.0
WH2_k127_7428538_0 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 304.0
WH2_k127_7428538_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003102 254.0
WH2_k127_7428538_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000001589 240.0
WH2_k127_7435905_0 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 511.0
WH2_k127_7435905_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 492.0
WH2_k127_7442081_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 1.082e-310 952.0
WH2_k127_7442081_1 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000002954 262.0
WH2_k127_7442081_2 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000000006857 205.0
WH2_k127_746823_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1194.0
WH2_k127_746823_1 PFAM AAA ATPase central domain protein K07478 - - 4.64e-207 652.0
WH2_k127_746823_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 535.0
WH2_k127_746823_3 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 293.0
WH2_k127_746823_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000008666 179.0
WH2_k127_7475204_0 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 556.0
WH2_k127_7475204_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000001931 241.0
WH2_k127_7475204_2 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000007528 227.0
WH2_k127_7475204_3 PFAM HNH endonuclease K07451 - - 0.0000000000000000000000000000000000000000009087 158.0
WH2_k127_7489561_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 596.0
WH2_k127_7499812_0 LUD domain - - - 9.068e-195 611.0
WH2_k127_7499812_1 LUD domain - - - 0.000000000000000000000000000000000000000007686 159.0
WH2_k127_7525773_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 404.0
WH2_k127_7525773_1 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.00000000000000000000000000000000000000000000000000001136 195.0
WH2_k127_7527329_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 3.297e-226 707.0
WH2_k127_7527329_1 response regulator - - - 1.206e-206 650.0
WH2_k127_7527329_2 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 410.0
WH2_k127_7529923_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009474 269.0
WH2_k127_7529923_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009782 267.0
WH2_k127_7551041_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 593.0
WH2_k127_7556620_0 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 455.0
WH2_k127_7556620_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006448 241.0
WH2_k127_7556620_2 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000000494 181.0
WH2_k127_7556620_3 - - - - 0.00000000002573 71.0
WH2_k127_7606230_0 General secretory system II, protein E domain protein K02652 - - 2.072e-267 830.0
WH2_k127_7606230_1 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004029 248.0
WH2_k127_7606230_2 Tetratricopeptide repeats - - - 0.0002532 48.0
WH2_k127_760747_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 592.0
WH2_k127_760747_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000000000000000000000006916 153.0
WH2_k127_7628839_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1157.0
WH2_k127_7628839_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 567.0
WH2_k127_7628839_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002658 269.0
WH2_k127_7628839_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001134 194.0
WH2_k127_7628839_4 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000002964 143.0
WH2_k127_7628839_5 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000003802 106.0
WH2_k127_7628839_6 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000001161 53.0
WH2_k127_7685995_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 9.264e-197 617.0
WH2_k127_7685995_1 Domain of unknown function (DUF4442) K02614 - - 0.000000000000000000000000000000000000000000000000000000003271 202.0
WH2_k127_7685995_3 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.0000004005 51.0
WH2_k127_7690446_0 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002575 267.0
WH2_k127_7690446_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000008748 189.0
WH2_k127_7690446_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000008343 157.0
WH2_k127_7690539_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1138.0
WH2_k127_7690539_1 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 323.0
WH2_k127_7700132_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 417.0
WH2_k127_7700132_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 357.0
WH2_k127_771757_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1809.0
WH2_k127_771757_1 cytochrome c - - - 0.00000000000000000000000000000000008913 134.0
WH2_k127_7722844_0 Histidine kinase K07716,K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 417.0
WH2_k127_7733912_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823,K12372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 338.0
WH2_k127_7733912_1 PFAM regulatory protein, ArsR - - - 0.0000000000000000000000000000000000000000000008598 166.0
WH2_k127_7733912_2 - - - - 0.000000000118 62.0
WH2_k127_7741713_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.505e-240 748.0
WH2_k127_7741713_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 589.0
WH2_k127_7759552_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 350.0
WH2_k127_7759552_1 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000557 284.0
WH2_k127_7771114_0 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005361 270.0
WH2_k127_7771114_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001985 247.0
WH2_k127_7771114_2 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000000002346 128.0
WH2_k127_779649_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 395.0
WH2_k127_779649_1 EVE domain - - - 0.0000000000000000000000000001341 116.0
WH2_k127_779649_2 nuclear chromosome segregation - - - 0.000000000000000000003157 109.0
WH2_k127_779649_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000001289 68.0
WH2_k127_7803238_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 325.0
WH2_k127_7803238_1 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000000000000000000000000001112 236.0
WH2_k127_7803238_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000003571 166.0
WH2_k127_7803238_3 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000001536 158.0
WH2_k127_7803238_4 - - - - 0.00000000000000000000000000000000004188 139.0
WH2_k127_7803238_5 - - - - 0.0000000000000000000000000000000001846 141.0
WH2_k127_7803238_6 LppC putative lipoprotein - - - 0.00000000000004164 79.0
WH2_k127_7815420_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 561.0
WH2_k127_7815420_1 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 332.0
WH2_k127_7850111_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 424.0
WH2_k127_7850111_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 406.0
WH2_k127_7850111_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 388.0
WH2_k127_7850111_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004269 279.0
WH2_k127_7850111_4 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000005538 198.0
WH2_k127_7850111_5 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000007597 131.0
WH2_k127_7850111_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000001469 85.0
WH2_k127_7889406_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.793e-275 848.0
WH2_k127_7889406_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 600.0
WH2_k127_7957213_0 TIGRFAM phosphonopyruvate decarboxylase-related protein K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 595.0
WH2_k127_7957213_1 cytidyltransferase-related domain K00952 - 2.7.7.1 0.00000000000000000000000000000007551 128.0
WH2_k127_7957213_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000005189 98.0
WH2_k127_7996660_0 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 571.0
WH2_k127_7996660_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 486.0
WH2_k127_7996660_2 PFAM Stage II sporulation K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 462.0
WH2_k127_8007240_0 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000001182 181.0
WH2_k127_8007240_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000004343 171.0
WH2_k127_8007240_2 Putative bacterial lipoprotein (DUF799) K21008 - - 0.00000000000001588 81.0
WH2_k127_8007240_3 Peptidoglycan-synthase activator LpoB - - - 0.0000000003156 68.0
WH2_k127_801134_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 588.0
WH2_k127_801134_1 cytidyltransferase-related domain K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001958 279.0
WH2_k127_8040681_0 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 439.0
WH2_k127_8040681_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000003605 250.0
WH2_k127_8040681_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000003823 126.0
WH2_k127_8040681_3 chemotaxis K03408,K03415 - - 0.0000000003312 67.0
WH2_k127_8040681_4 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000006455 60.0
WH2_k127_8044906_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000108 267.0
WH2_k127_8044906_1 - - - - 0.00000000000000000000000000000000000000000000001989 175.0
WH2_k127_8093779_0 L-lactate permease K03303 - - 2.467e-219 687.0
WH2_k127_8093779_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001623 271.0
WH2_k127_8109919_0 DbpA RNA binding domain K05591 - 3.6.4.13 3.692e-238 742.0
WH2_k127_8109919_1 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000000000000000002899 176.0
WH2_k127_8132192_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 4.228e-214 671.0
WH2_k127_8132192_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 390.0
WH2_k127_8154171_0 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 572.0
WH2_k127_8154171_1 regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 343.0
WH2_k127_8154171_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000009271 244.0
WH2_k127_8154171_3 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000002703 104.0
WH2_k127_8154521_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 391.0
WH2_k127_8154521_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000005346 152.0
WH2_k127_8154521_2 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000003557 92.0
WH2_k127_8163646_0 manually curated K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 521.0
WH2_k127_8178706_0 PFAM outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005315 285.0
WH2_k127_8178706_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000004013 249.0
WH2_k127_8178706_2 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000005004 218.0
WH2_k127_8187576_0 Domains REC, HisKA, HATPase_c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 384.0
WH2_k127_8187576_1 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 305.0
WH2_k127_8198271_0 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 387.0
WH2_k127_8198271_1 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 331.0
WH2_k127_8221184_0 PFAM NHL repeat containing protein - - - 0.00000000000002042 84.0
WH2_k127_8221184_1 SMART Fibronectin type III domain protein - - - 0.000000000004342 77.0
WH2_k127_8221184_2 NHL repeat containing protein - - - 0.000000000007323 76.0
WH2_k127_8221184_3 WD40-like Beta Propeller Repeat K03641,K08676 - - 0.00000001388 67.0
WH2_k127_8221184_4 Fibronectin type III domain protein - - - 0.00001129 53.0
WH2_k127_8224052_0 type IV pilus modification protein PilV K02671,K02681 - - 0.000000000000000000000000000000000000633 144.0
WH2_k127_8224052_1 pilus assembly protein PilW K02672 - - 0.000000000000000000000000000000000001764 148.0
WH2_k127_8224052_2 - - - - 0.00000000000000000000000000006526 124.0
WH2_k127_8287021_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 600.0
WH2_k127_8287021_1 NAD(P)H dehydrogenase (quinone) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 349.0
WH2_k127_8289861_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 6.896e-247 768.0
WH2_k127_8289861_1 Cytochrome c bacterial - - - 1.915e-229 720.0
WH2_k127_8289861_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.133e-204 640.0
WH2_k127_8311019_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 409.0
WH2_k127_8311019_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003449 274.0
WH2_k127_8363028_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K00595 - 2.1.1.132 5.573e-210 657.0
WH2_k127_8363028_1 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000000000000001276 168.0
WH2_k127_8363028_2 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000002987 108.0
WH2_k127_8411034_0 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 437.0
WH2_k127_8411034_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000003293 141.0
WH2_k127_8411034_2 PFAM PKD domain containing protein - - - 0.00000000000000000000000000001179 137.0
WH2_k127_8411034_3 fibronectin type III domain protein - - - 0.000000000131 68.0
WH2_k127_8412461_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 325.0
WH2_k127_8412461_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000009269 165.0
WH2_k127_8412461_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000872 132.0
WH2_k127_8431085_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 507.0
WH2_k127_8431085_1 Protein of unknown function (DUF2860) - - - 0.0000000000000000000000000000000000000000000000000000000000000002604 228.0
WH2_k127_8431085_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000001274 175.0
WH2_k127_8431085_3 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.7.99.1 0.00000000000000000000000005918 111.0
WH2_k127_8432862_0 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 430.0
WH2_k127_8432862_1 Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L- methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by K22466 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009152 276.0
WH2_k127_8432862_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000005028 193.0
WH2_k127_8444699_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 598.0
WH2_k127_8444699_1 FCD K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 342.0
WH2_k127_8444699_2 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000001066 226.0
WH2_k127_8467925_0 RNA-DNA hybrid ribonuclease activity K02335,K03469 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7,3.1.26.4 2.326e-237 741.0
WH2_k127_8478734_0 4Fe-4S binding domain - - - 1.361e-227 715.0
WH2_k127_8478734_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 443.0
WH2_k127_8478734_2 Domain of unknown function (DUF2019) - - - 0.00000000000000000005573 94.0
WH2_k127_8478734_3 PFAM multi antimicrobial extrusion protein MatE - - - 0.00000000000004975 76.0
WH2_k127_8478734_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313,K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.0000000255 57.0
WH2_k127_8511874_0 SMART Elongator protein 3 MiaB NifB - - - 3.289e-232 729.0
WH2_k127_8542532_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 7.964e-201 633.0
WH2_k127_8542532_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.589e-195 614.0
WH2_k127_8542532_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 505.0
WH2_k127_8542532_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 321.0
WH2_k127_8542532_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000005632 105.0
WH2_k127_8542532_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000006911 108.0
WH2_k127_8542532_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000001034 100.0
WH2_k127_8542532_7 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000007758 90.0
WH2_k127_8548622_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 8.699e-206 648.0
WH2_k127_8548622_1 CBS domain containing protein K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 364.0
WH2_k127_8548622_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000002486 56.0
WH2_k127_856270_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 385.0
WH2_k127_856270_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000003829 174.0
WH2_k127_8578058_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 345.0
WH2_k127_8578058_1 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000118 205.0
WH2_k127_8581070_0 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 1.388e-221 697.0
WH2_k127_8581070_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000002219 75.0
WH2_k127_861576_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
WH2_k127_861576_1 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000001443 112.0
WH2_k127_8656099_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 2.07e-199 630.0
WH2_k127_8656099_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 422.0
WH2_k127_8656099_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 396.0
WH2_k127_8658859_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 326.0
WH2_k127_8658859_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000001047 207.0
WH2_k127_8658859_2 Putative zinc-finger - - - 0.0000000000000000000000000000000001827 146.0
WH2_k127_865999_0 Domain of unknown function (DUF2341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 398.0
WH2_k127_865999_1 Alpha-1,2-mannosidase - - - 0.000000000000000000000000002058 115.0
WH2_k127_865999_2 Transposase IS200 like - - - 0.00002639 50.0
WH2_k127_8682050_0 PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 308.0
WH2_k127_8682050_1 SNARE associated Golgi protein - - - 0.0000000000000000000000002938 114.0
WH2_k127_8682050_2 SlyX K03745 - - 0.0000001544 53.0
WH2_k127_8744676_0 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 3.544e-244 758.0
WH2_k127_8744676_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 453.0
WH2_k127_8744676_2 PFAM type IV pilus assembly PilZ - - - 0.0000000000000000000001391 101.0
WH2_k127_8772033_0 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 524.0
WH2_k127_8772033_1 sensor histidine kinase - - - 0.0000000000000000000000000000002503 123.0
WH2_k127_8803645_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 458.0
WH2_k127_8803645_1 positive regulation of growth rate - - - 0.000003529 51.0
WH2_k127_8829366_0 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002034 268.0
WH2_k127_8829366_1 Peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008591 274.0
WH2_k127_8829366_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000005918 153.0
WH2_k127_8894092_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1279.0
WH2_k127_8894092_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 5.071e-248 771.0
WH2_k127_8969115_0 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 356.0
WH2_k127_8969115_1 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 321.0
WH2_k127_8969115_2 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 306.0
WH2_k127_8969115_3 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 294.0
WH2_k127_8969115_4 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004011 275.0
WH2_k127_8969115_5 Pfam:TPM K08988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004369 275.0
WH2_k127_8969115_6 PQ loop repeat K15383 - - 0.00000000000000000000000000004788 118.0
WH2_k127_8969115_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 0.00000002394 56.0
WH2_k127_8980383_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 532.0
WH2_k127_8980383_1 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 478.0
WH2_k127_8980383_2 CRISPR-associated endoribonuclease Cas6 - - - 0.000394 49.0
WH2_k127_8981006_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 444.0
WH2_k127_8981006_1 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 401.0
WH2_k127_8981006_2 - - - - 0.00000000000000000000000002543 109.0
WH2_k127_8983859_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 528.0
WH2_k127_8983859_1 PFAM type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 362.0
WH2_k127_8983859_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000009777 87.0
WH2_k127_8985162_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 535.0
WH2_k127_8985162_1 NUBPL iron-transfer P-loop NTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003964 269.0
WH2_k127_8985162_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000004906 97.0
WH2_k127_8985162_3 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000001104 68.0
WH2_k127_8987399_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 604.0
WH2_k127_8987399_1 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 529.0
WH2_k127_8987399_2 Putative exonuclease, RdgC K03554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 337.0
WH2_k127_8997725_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 571.0
WH2_k127_8997725_1 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 541.0
WH2_k127_8997725_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 320.0
WH2_k127_8997725_3 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000001717 141.0
WH2_k127_899821_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 413.0
WH2_k127_899821_1 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 376.0
WH2_k127_899821_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004943 235.0
WH2_k127_899821_3 signal-transduction protein containing cAMP-binding and CBS domains K02342,K07182 - 2.7.7.7 0.0000000000000000000000000000000000000000000000001717 192.0
WH2_k127_902302_0 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 492.0
WH2_k127_902302_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 398.0
WH2_k127_902302_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003893 258.0
WH2_k127_9026966_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.217e-197 619.0
WH2_k127_9026966_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 297.0
WH2_k127_9026966_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000148 152.0
WH2_k127_9026966_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00002795 50.0
WH2_k127_9030683_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.759e-281 872.0
WH2_k127_9030683_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 549.0
WH2_k127_9030683_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 510.0
WH2_k127_9030683_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 495.0
WH2_k127_9030683_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 428.0
WH2_k127_9030683_5 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 392.0
WH2_k127_9030683_6 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 283.0
WH2_k127_9030683_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009808 276.0
WH2_k127_9030683_8 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000000001437 129.0
WH2_k127_9048646_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 417.0
WH2_k127_9077154_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.811e-225 706.0
WH2_k127_9077154_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 453.0
WH2_k127_9077154_2 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000003444 172.0
WH2_k127_9078584_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 2.022e-210 662.0
WH2_k127_9078584_1 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008958 264.0
WH2_k127_9084973_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 354.0
WH2_k127_9084973_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 296.0
WH2_k127_9084973_2 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000005948 208.0
WH2_k127_9093636_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 6.29e-250 781.0
WH2_k127_9160577_0 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000091 224.0
WH2_k127_9160577_1 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000166 220.0
WH2_k127_9160577_2 General secretory system II, protein E domain protein K02652 - - 0.000000000000001388 79.0
WH2_k127_9186864_0 PFAM phosphate acetyl butaryl transferase K00625,K13788 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 346.0
WH2_k127_9186864_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 302.0
WH2_k127_9186864_2 - - - - 0.0000000008034 69.0
WH2_k127_9282436_0 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 453.0
WH2_k127_9282436_1 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000121 116.0
WH2_k127_929494_0 4Fe-4S dicluster domain K11473 - - 4.545e-259 801.0
WH2_k127_929494_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000003923 205.0
WH2_k127_929494_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000001648 205.0
WH2_k127_9340435_0 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 410.0
WH2_k127_9340435_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 318.0
WH2_k127_9350960_0 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 461.0
WH2_k127_9350960_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 323.0
WH2_k127_9350960_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000001214 74.0
WH2_k127_9356557_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 526.0
WH2_k127_9356557_1 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000001406 203.0
WH2_k127_9357224_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 610.0
WH2_k127_9357224_1 Tetracycline repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 303.0
WH2_k127_9357224_2 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.000000000000000000000000000000000000000008682 154.0
WH2_k127_937232_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 327.0
WH2_k127_937232_1 Na+/Pi-cotransporter K03324 - - 0.00000000000000000000000000000000000000000002505 174.0
WH2_k127_9378303_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 7.142e-201 628.0
WH2_k127_9378303_1 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 546.0
WH2_k127_9378303_2 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 537.0
WH2_k127_9378303_3 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000003701 170.0
WH2_k127_9388803_0 Chain length determinant protein K16554 - - 1.74e-213 681.0
WH2_k127_9391312_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 8.452e-220 701.0
WH2_k127_9391312_1 Elongation factor P K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 325.0
WH2_k127_9391312_2 PFAM MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001697 244.0
WH2_k127_9391312_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000001198 185.0
WH2_k127_9391312_4 PFAM RNA-binding S4 domain protein K14761 - - 0.0000000000000000000001396 98.0
WH2_k127_9391312_5 - - - - 0.00000000000000096 80.0
WH2_k127_9391312_6 - - - - 0.0000001912 53.0
WH2_k127_941078_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 420.0
WH2_k127_941078_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 387.0
WH2_k127_9456090_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.516e-299 921.0
WH2_k127_9456090_1 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 606.0
WH2_k127_9465021_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 6.918e-276 853.0
WH2_k127_9465021_1 Protein of unknown function (DUF1015) - - - 7.676e-201 632.0
WH2_k127_9465021_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 460.0
WH2_k127_9465021_3 PFAM NLP P60 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 315.0
WH2_k127_9465021_4 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000001264 235.0
WH2_k127_9473166_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 402.0
WH2_k127_9473166_1 PFAM histidine triad (HIT) protein - - - 0.0000000000000000000000000000000000000000000000000000000000004303 213.0
WH2_k127_9473166_2 AMP binding - - - 0.00000000000000000000000000000000000001599 149.0
WH2_k127_9492406_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 564.0
WH2_k127_9492406_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 412.0
WH2_k127_9495563_0 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 293.0
WH2_k127_9495563_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000003229 253.0
WH2_k127_9495563_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000001967 209.0
WH2_k127_9495563_3 Water Stress and Hypersensitive response - - - 0.000000000000000000000000002809 120.0
WH2_k127_949776_0 PFAM major facilitator superfamily MFS_1 - - - 1.554e-203 638.0
WH2_k127_949776_1 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006729 244.0
WH2_k127_949776_2 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005738 244.0
WH2_k127_949776_3 - - - - 0.0000000000000000000002188 102.0
WH2_k127_9505488_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1257.0
WH2_k127_9531097_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 310.0
WH2_k127_9531097_1 SOS response associated peptidase (SRAP) - - - 0.0003507 45.0
WH2_k127_9533998_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 504.0
WH2_k127_9533998_1 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 416.0
WH2_k127_9533998_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 409.0
WH2_k127_9533998_3 PTS system fructose IIA component K02793 - 2.7.1.191 0.000000000000000000000000000000000000000000001066 168.0
WH2_k127_9533998_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000001213 73.0
WH2_k127_9575711_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.191e-278 871.0
WH2_k127_9575711_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 525.0
WH2_k127_9575711_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 356.0
WH2_k127_9575711_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000002902 127.0
WH2_k127_9575711_4 General secretory system II, protein E domain protein K02652 - - 0.00000000000000000000000000000002951 129.0
WH2_k127_9579341_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 475.0
WH2_k127_9579341_1 family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 332.0
WH2_k127_9579341_2 RNA pseudouridylate synthase K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008437 276.0
WH2_k127_9579341_3 SEC-C motif K09858 - - 0.00000000000000000000000000000000000000000000000000000000000209 213.0
WH2_k127_9579341_4 Stress responsive A/B Barrel Domain - - - 0.0000000000000000000000000000000001403 134.0
WH2_k127_9586342_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.887e-251 776.0
WH2_k127_9586342_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 441.0
WH2_k127_9586342_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 370.0
WH2_k127_9586342_3 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000003599 183.0
WH2_k127_9586342_4 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000000674 137.0
WH2_k127_9599371_0 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 317.0
WH2_k127_9599371_1 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 299.0
WH2_k127_9613894_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 333.0
WH2_k127_9613894_1 Collagenase K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005215 244.0
WH2_k127_9613894_2 sensor histidine kinase response - - - 0.000000000000000000000000000000000000000000000009421 184.0
WH2_k127_9654654_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 533.0
WH2_k127_9654654_1 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000001221 190.0
WH2_k127_9654654_2 Recombinase zinc beta ribbon domain - - - 0.0000001593 55.0
WH2_k127_9708047_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.441e-194 610.0
WH2_k127_9708047_1 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009453 250.0
WH2_k127_9708047_2 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000004491 161.0
WH2_k127_9708047_3 structural constituent of ribosome K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000005185 109.0
WH2_k127_9715789_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 1.754e-212 667.0
WH2_k127_9715789_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 570.0
WH2_k127_9715789_2 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000000000007979 149.0
WH2_k127_9733970_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.223e-290 905.0
WH2_k127_9733970_1 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 345.0
WH2_k127_9733970_2 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000003048 220.0
WH2_k127_9733970_3 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000003903 174.0
WH2_k127_9733970_4 - - - - 0.0000000000000002649 83.0
WH2_k127_9741145_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 509.0
WH2_k127_9741145_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 459.0
WH2_k127_9779675_0 PFAM Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 392.0
WH2_k127_9779675_1 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 344.0
WH2_k127_9779675_2 Dodecin K09165 - - 0.00000000000001845 72.0
WH2_k127_9779675_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000009707 66.0
WH2_k127_9793323_0 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 458.0
WH2_k127_9793323_1 Sir2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 372.0
WH2_k127_9793323_2 Aminoacyl-tRNA editing domain K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000001994 233.0
WH2_k127_9793323_3 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000001258 158.0
WH2_k127_9793323_4 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000003646 95.0
WH2_k127_9814505_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 607.0
WH2_k127_9814505_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 421.0
WH2_k127_9814505_2 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 321.0
WH2_k127_9837695_0 Formate/nitrite transporter K06212,K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 422.0
WH2_k127_9837695_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 338.0
WH2_k127_9857921_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 364.0
WH2_k127_9857921_1 PFAM Maf family protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001684 263.0
WH2_k127_9890413_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 555.0
WH2_k127_9890413_1 PFAM 4Fe-4S dicluster domain K04014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 430.0
WH2_k127_9890413_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000001402 209.0
WH2_k127_9890413_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000002601 159.0
WH2_k127_9898691_0 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 389.0
WH2_k127_9898691_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000001001 209.0
WH2_k127_9898691_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000003012 132.0
WH2_k127_9898691_3 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00001756 47.0
WH2_k127_9930630_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 4.887e-297 921.0
WH2_k127_9930630_1 PFAM amino acid-binding ACT domain protein K03567 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 287.0
WH2_k127_9930630_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003222 273.0
WH2_k127_9930630_3 Cation efflux family - - - 0.0000000000008448 68.0
WH2_k127_9939054_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 602.0
WH2_k127_9939054_1 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 423.0
WH2_k127_9939054_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 398.0
WH2_k127_9939054_3 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 410.0
WH2_k127_9939054_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000003505 211.0
WH2_k127_9939054_5 HEAT repeat - - - 0.00000000000000000000000000000000000000000000000000000002335 203.0
WH2_k127_9939054_6 - - - - 0.0000000000000000000001102 102.0
WH2_k127_9939054_7 response regulator, receiver - - - 0.00001112 54.0
WH2_k127_99683_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 4.254e-226 709.0
WH2_k127_9971792_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 385.0
WH2_k127_9971792_1 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002923 276.0
WH2_k127_9983177_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 443.0
WH2_k127_9983177_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 426.0
WH2_k127_9999547_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 460.0
WH2_k127_9999547_1 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 403.0
WH2_k127_9999547_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 351.0
WH2_k127_9999547_3 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 314.0
WH2_k127_9999547_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000002595 254.0