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Overview

ID MAG04111
Name WH2_bin.16
Sample SMP0107
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family GWC2-71-9
Genus SPDF01
Species
Assembly information
Completeness (%) 75.74
Contamination (%) 1.43
GC content (%) 70.0
N50 (bp) 6,443
Genome size (bp) 2,040,901

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1998

Gene name Description KEGG GOs EC E-value Score Sequence
WH2_k127_10032617_0 tRNA synthetases class I (M) K01874 - 6.1.1.10 3.665e-203 643.0
WH2_k127_10032617_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000004149 204.0
WH2_k127_10032617_2 PFAM peptidase - - - 0.0000000000000000000000000000000000000000003133 169.0
WH2_k127_10058078_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 512.0
WH2_k127_10093263_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 453.0
WH2_k127_10093263_1 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 399.0
WH2_k127_10093263_2 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 357.0
WH2_k127_10093263_3 PFAM glycosyl transferase group 1 K12995 - 2.4.1.348 0.00000000000000000000000000000000000000000000000000000004795 210.0
WH2_k127_10093263_4 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000003719 182.0
WH2_k127_10093263_5 DNA recombination-mediator protein A K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.0000000000000004419 85.0
WH2_k127_10093263_6 PFAM Glycosyl transferases group 1 - - - 0.00005243 51.0
WH2_k127_10119659_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 305.0
WH2_k127_10119659_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 289.0
WH2_k127_10119659_2 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000001472 55.0
WH2_k127_10121832_0 E1-E2 ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 418.0
WH2_k127_10121832_1 Heavy-metal-associated domain K07213 - - 0.0000000000004189 71.0
WH2_k127_10126300_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 310.0
WH2_k127_10134758_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 503.0
WH2_k127_10134758_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 370.0
WH2_k127_10134758_2 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000004966 214.0
WH2_k127_10134758_3 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000009985 140.0
WH2_k127_10174686_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.625e-202 654.0
WH2_k127_10174686_1 fructose 1,6-bisphosphate 1-phosphatase activity K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 419.0
WH2_k127_10174686_2 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000006774 101.0
WH2_k127_10186633_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 346.0
WH2_k127_10186633_1 peptidoglycan biosynthetic process K03980 GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 351.0
WH2_k127_10186633_2 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000005791 248.0
WH2_k127_10186633_3 methyltransferase activity - - - 0.00000000000000000000000000000000000000008813 164.0
WH2_k127_10186633_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000003037 119.0
WH2_k127_10195258_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000171 281.0
WH2_k127_10195258_1 O-acyltransferase activity - - - 0.00000000000000000000000000000000000004328 144.0
WH2_k127_10252964_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 490.0
WH2_k127_10252964_1 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 352.0
WH2_k127_10252964_2 peptide catabolic process - - - 0.0000000000006725 82.0
WH2_k127_10284203_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 542.0
WH2_k127_10284203_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 530.0
WH2_k127_10284203_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000006849 244.0
WH2_k127_10284203_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000868 86.0
WH2_k127_10329665_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 494.0
WH2_k127_10329665_1 Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 314.0
WH2_k127_10329665_2 Sugar nucleotidyl transferase - - - 0.000000000000000000000000000000003072 139.0
WH2_k127_10329665_3 - - - - 0.000000000000000001805 92.0
WH2_k127_10329665_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000005743 69.0
WH2_k127_10349332_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 359.0
WH2_k127_10349332_1 Domain of unknown function (DUF4397) - - - 0.00000000000000000000008111 100.0
WH2_k127_10349332_2 Recombinase zinc beta ribbon domain - - - 0.0003683 45.0
WH2_k127_10350841_0 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 300.0
WH2_k127_10350841_1 DbpA RNA binding domain K05592 - 3.6.4.13 0.000000000000000000000005663 116.0
WH2_k127_10428750_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 471.0
WH2_k127_10428750_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 358.0
WH2_k127_10428750_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 352.0
WH2_k127_10428750_3 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000267 277.0
WH2_k127_10428750_4 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000002321 242.0
WH2_k127_10428750_5 Part of the ABC transporter FtsEX involved in K09811 - - 0.00000000000000000000000006955 113.0
WH2_k127_10428750_6 - - - - 0.00000000000000000000003574 110.0
WH2_k127_10442556_0 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000002236 231.0
WH2_k127_10442556_1 AAA ATPase domain - - - 0.0000000001986 72.0
WH2_k127_10481369_0 phosphorelay signal transduction system K07713 - - 0.0000000000000000000000000000000000000000000000000000000000001046 222.0
WH2_k127_10481369_1 - - - - 0.000000000000000000000000000000000001151 153.0
WH2_k127_10481369_2 Stress-responsive transcriptional regulator K03973 - - 0.0000000000000002842 82.0
WH2_k127_10596122_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 402.0
WH2_k127_10627397_0 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 288.0
WH2_k127_10627397_1 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000003333 216.0
WH2_k127_10627397_2 - - - - 0.0000000000000000004764 95.0
WH2_k127_10655736_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 400.0
WH2_k127_10655736_1 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008179 286.0
WH2_k127_10655736_10 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000008213 93.0
WH2_k127_10655736_11 Outer membrane protein beta-barrel domain - - - 0.0000000000000003456 87.0
WH2_k127_10655736_12 Opacity protein - - - 0.00000000004504 71.0
WH2_k127_10655736_2 - - - - 0.0000000000000000000000000000000000000000000000000000000211 212.0
WH2_k127_10655736_3 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000002304 207.0
WH2_k127_10655736_4 Redoxin - - - 0.0000000000000000000000000000000000000000000000000008648 201.0
WH2_k127_10655736_5 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000007624 188.0
WH2_k127_10655736_6 Glycosyl transferase family 2 K08301 - - 0.00000000000000000000000000000000000000000000000003352 187.0
WH2_k127_10655736_7 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000002332 190.0
WH2_k127_10655736_8 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000002677 178.0
WH2_k127_10655736_9 Opacity protein - - - 0.00000000000000007864 89.0
WH2_k127_10712565_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 304.0
WH2_k127_10712565_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000186 215.0
WH2_k127_10712565_2 acetyltransferase - - - 0.00000000000000000000000000000003187 132.0
WH2_k127_10712565_3 - - - - 0.0000000004651 63.0
WH2_k127_10761365_0 Glycosyl transferase 4-like K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 322.0
WH2_k127_10761365_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 286.0
WH2_k127_10761365_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K04040,K20616 - 2.5.1.133,2.5.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000005727 275.0
WH2_k127_10761365_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000001443 218.0
WH2_k127_10761365_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000001596 119.0
WH2_k127_10761365_5 hydrolase K21471 - - 0.000000000000000000002204 108.0
WH2_k127_10776192_0 sulfatase K01130 - 3.1.6.1 5.545e-291 902.0
WH2_k127_10776192_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 364.0
WH2_k127_10776192_2 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 342.0
WH2_k127_10776192_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 296.0
WH2_k127_10776192_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000001108 162.0
WH2_k127_10776192_5 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.00000000000000000000000000000000000009188 150.0
WH2_k127_10776192_6 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000002636 128.0
WH2_k127_10776192_7 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 0.0000000000000000001617 91.0
WH2_k127_10776192_8 LytR cell envelope-related transcriptional attenuator - - - 0.000000000000002898 87.0
WH2_k127_10816420_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 343.0
WH2_k127_10816420_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000001332 223.0
WH2_k127_10816420_2 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000000000000001032 146.0
WH2_k127_10816420_3 TPM domain K06872 - - 0.00000000000000000000000000003776 134.0
WH2_k127_1084870_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000001209 244.0
WH2_k127_1084870_1 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000001607 177.0
WH2_k127_1084870_2 PFAM TPR repeat-containing protein - - - 0.00000002502 66.0
WH2_k127_1084870_3 Cytochrome c554 and c-prime - - - 0.00001977 57.0
WH2_k127_11080_0 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 364.0
WH2_k127_11080_1 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000003082 145.0
WH2_k127_11080_2 DinB superfamily - - - 0.00000000000006745 82.0
WH2_k127_1148424_0 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 458.0
WH2_k127_1148424_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 362.0
WH2_k127_1148424_2 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 309.0
WH2_k127_1148424_3 Transglycosylase associated protein - - - 0.000000000000000000000004499 104.0
WH2_k127_1148424_4 - - - - 0.000000000000000000313 97.0
WH2_k127_1148424_5 Predicted membrane protein (DUF2231) - - - 0.0000000000004611 78.0
WH2_k127_1180551_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 2.524e-251 792.0
WH2_k127_1180551_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 283.0
WH2_k127_1180551_2 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000002188 166.0
WH2_k127_1180551_3 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000001087 111.0
WH2_k127_1180551_4 VKc - - - 0.00000000000000000000001325 107.0
WH2_k127_1180551_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000002356 96.0
WH2_k127_1180551_6 - - - - 0.000000000000001237 81.0
WH2_k127_1218328_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 416.0
WH2_k127_1218328_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000003386 159.0
WH2_k127_1218328_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000004398 153.0
WH2_k127_1218328_3 O-acyltransferase activity - - - 0.000000000000000000000000000000003 133.0
WH2_k127_1218328_4 - - - - 0.000000000000005565 87.0
WH2_k127_1221204_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 336.0
WH2_k127_1221204_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 317.0
WH2_k127_123232_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 3.479e-231 725.0
WH2_k127_123232_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 347.0
WH2_k127_123232_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000002141 188.0
WH2_k127_123232_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000002538 192.0
WH2_k127_1237680_0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 440.0
WH2_k127_1237680_1 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000002592 160.0
WH2_k127_1237680_2 Rhodanese Homology Domain K01069 - 3.1.2.6 0.0000000000000000000000000000000000002209 151.0
WH2_k127_1245225_0 amino acid K03294 - - 0.000000000000000000000000000000000003077 139.0
WH2_k127_1245225_1 - - - - 0.00000000000000000000000000000000002291 139.0
WH2_k127_1245225_2 Glyoxalase-like domain - - - 0.00000000000000000000000609 106.0
WH2_k127_1245225_3 Glucose / Sorbosone dehydrogenase - - - 0.000002522 55.0
WH2_k127_1250501_0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 483.0
WH2_k127_1250501_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 310.0
WH2_k127_1250501_2 nucleotidyl transferase K01841,K03430,K07281,K07291,K09809,K22424 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0016780 2.6.1.37,2.7.3.13,2.7.7.74,2.7.8.12,2.7.8.34,5.4.2.9 0.000000000000000000000000000000000000000000000000000000004962 213.0
WH2_k127_1250501_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000007906 179.0
WH2_k127_1250501_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000002316 161.0
WH2_k127_1250501_5 PFAM glycosyl transferase family 9 K02843 - - 0.0000000000000000000000005708 109.0
WH2_k127_1355095_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 2.146e-264 835.0
WH2_k127_1355095_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 8.838e-240 747.0
WH2_k127_1355095_2 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 387.0
WH2_k127_1355095_3 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005603 274.0
WH2_k127_1355095_4 Serine dehydratase beta chain K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000002056 254.0
WH2_k127_1355095_5 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000002332 203.0
WH2_k127_1355095_6 - - - - 0.0000000000000000000000000000000001161 141.0
WH2_k127_1358400_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 3.045e-221 695.0
WH2_k127_1358400_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01761 - 4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 573.0
WH2_k127_1358400_10 Prokaryotic N-terminal methylation motif K02671 - - 0.0000000000001543 76.0
WH2_k127_1358400_2 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 488.0
WH2_k127_1358400_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 439.0
WH2_k127_1358400_4 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 417.0
WH2_k127_1358400_5 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000004294 204.0
WH2_k127_1358400_6 Tfp pilus assembly protein FimT - - - 0.0000000000000000000000000000000000002555 150.0
WH2_k127_1358400_7 amine dehydrogenase activity - - - 0.000000000000000000000000000000007385 146.0
WH2_k127_1358400_9 Zincin-like metallopeptidase - - - 0.00000000000000009862 89.0
WH2_k127_1432087_0 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000004019 156.0
WH2_k127_1432087_1 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000005829 124.0
WH2_k127_1432087_2 PFAM SpoVT AbrB like domain K07172 - - 0.000000000000000000000003718 104.0
WH2_k127_1432087_3 - - - - 0.000000000000000000000004822 114.0
WH2_k127_1432087_4 - - - - 0.000000000000000000000496 98.0
WH2_k127_1432087_5 PFAM GGDEF domain containing protein - - - 0.0000000000000000000009754 100.0
WH2_k127_1432087_6 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000004186 92.0
WH2_k127_1432087_7 - - - - 0.0000000004504 70.0
WH2_k127_1433825_0 Voltage gated chloride channel K03281 - - 6.455e-214 679.0
WH2_k127_1433825_1 Reductase C-terminal K05297 - 1.18.1.1 1.813e-207 658.0
WH2_k127_1433825_10 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000003019 216.0
WH2_k127_1433825_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000006104 217.0
WH2_k127_1433825_12 - - - - 0.0000000000000000000000000000000000000000000000001562 186.0
WH2_k127_1433825_13 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000000000000000000001035 181.0
WH2_k127_1433825_14 DinB superfamily - - - 0.0000000000000000000000000000000000000000005367 168.0
WH2_k127_1433825_15 - - - - 0.000000000000000000000000000000000000000006227 160.0
WH2_k127_1433825_16 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000002571 153.0
WH2_k127_1433825_17 - - - - 0.0000000000000000000000000000000000001949 147.0
WH2_k127_1433825_18 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000001084 146.0
WH2_k127_1433825_19 Transcriptional regulator - - - 0.000000000000000000000000000000006789 136.0
WH2_k127_1433825_2 PFAM cytochrome c oxidase subunit I K02274 - 1.9.3.1 2.335e-206 655.0
WH2_k127_1433825_20 Domain of unknown function (DUF1858) - - - 0.00000000000000000000000000000001316 138.0
WH2_k127_1433825_21 conserved protein (DUF2249) - - - 0.000000000000000000000000000004623 130.0
WH2_k127_1433825_22 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000001109 131.0
WH2_k127_1433825_23 response regulator - - - 0.000000000000000000000004162 111.0
WH2_k127_1433825_24 conserved protein (DUF2249) - - - 0.0000000000000000000434 99.0
WH2_k127_1433825_25 Iron-sulfur cluster assembly protein - - - 0.0000000000000004563 92.0
WH2_k127_1433825_27 Cupin domain - - - 0.000000003614 63.0
WH2_k127_1433825_28 - - - - 0.000006165 53.0
WH2_k127_1433825_29 - - - - 0.0004291 51.0
WH2_k127_1433825_3 MmgE PrpD family protein K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 552.0
WH2_k127_1433825_4 PFAM tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 364.0
WH2_k127_1433825_5 Uracil DNA glycosylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 309.0
WH2_k127_1433825_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 296.0
WH2_k127_1433825_7 Electron transporter SenC - - - 0.0000000000000000000000000000000000000000000000000000000000000000001396 236.0
WH2_k127_1433825_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
WH2_k127_1433825_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000009561 218.0
WH2_k127_1455690_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 571.0
WH2_k127_1455690_1 small subunit K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 406.0
WH2_k127_1502216_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 563.0
WH2_k127_1502216_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001036 290.0
WH2_k127_1502216_2 Thioesterase superfamily - - - 0.0000000000000000000000000000000000018 143.0
WH2_k127_1502216_3 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000002998 104.0
WH2_k127_1502216_4 FES K03575 - - 0.000000000000000002443 87.0
WH2_k127_1502216_5 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000001175 77.0
WH2_k127_1504579_0 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 410.0
WH2_k127_1504579_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000003118 236.0
WH2_k127_1504579_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000007062 126.0
WH2_k127_1504579_3 Transposase IS200 like - - - 0.0000000000000000000006567 100.0
WH2_k127_1504579_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000001161 73.0
WH2_k127_1504579_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000002573 71.0
WH2_k127_1504579_6 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0008684 44.0
WH2_k127_1545253_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000003193 236.0
WH2_k127_1545253_1 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000007164 203.0
WH2_k127_1545253_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000448 164.0
WH2_k127_1545253_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000009773 103.0
WH2_k127_1545253_4 Belongs to the UPF0754 family - - - 0.0000000000007584 81.0
WH2_k127_1584721_0 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 375.0
WH2_k127_1584721_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000006977 265.0
WH2_k127_1584721_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000965 86.0
WH2_k127_1596557_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 344.0
WH2_k127_1596557_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003549 275.0
WH2_k127_1596557_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.00000000000000000000000000000000655 136.0
WH2_k127_1679221_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.728e-233 756.0
WH2_k127_1679221_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 501.0
WH2_k127_1679221_2 neurotransmitter:sodium symporter activity K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008789 253.0
WH2_k127_1679221_3 - - - - 0.000000000000000002264 91.0
WH2_k127_171987_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 546.0
WH2_k127_171987_1 rod shape-determining protein MreD K03571 - - 0.000000000000000000000000002035 115.0
WH2_k127_1730312_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 484.0
WH2_k127_1730312_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 420.0
WH2_k127_1730312_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 300.0
WH2_k127_1730312_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000001081 203.0
WH2_k127_1730312_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000002183 202.0
WH2_k127_1730312_5 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000002575 157.0
WH2_k127_1730312_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000575 89.0
WH2_k127_1730312_7 Ribosomal protein L36 K02919 - - 0.000000000000001599 77.0
WH2_k127_1730312_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000001003 61.0
WH2_k127_1730312_9 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000002045 70.0
WH2_k127_1775673_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 621.0
WH2_k127_1775673_1 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 552.0
WH2_k127_1775673_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00007329 54.0
WH2_k127_1775673_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0009008 48.0
WH2_k127_1775673_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 516.0
WH2_k127_1775673_3 fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 479.0
WH2_k127_1775673_4 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 322.0
WH2_k127_1775673_5 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003988 276.0
WH2_k127_1775673_6 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000001206 209.0
WH2_k127_1775673_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000001165 135.0
WH2_k127_1775673_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000001912 100.0
WH2_k127_1775673_9 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000006144 76.0
WH2_k127_1835013_0 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 535.0
WH2_k127_1835013_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000001004 222.0
WH2_k127_1835013_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000005296 191.0
WH2_k127_1840738_0 Nickel-dependent hydrogenase K05922,K06281 - 1.12.5.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 422.0
WH2_k127_1840738_1 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000004564 232.0
WH2_k127_1840738_2 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
WH2_k127_1840738_3 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000009727 175.0
WH2_k127_1840738_4 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000000001757 136.0
WH2_k127_1840738_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0002451 48.0
WH2_k127_1877836_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 597.0
WH2_k127_1877836_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 301.0
WH2_k127_188176_0 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 419.0
WH2_k127_188176_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 385.0
WH2_k127_188176_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000001605 249.0
WH2_k127_188176_3 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000000001149 185.0
WH2_k127_188176_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000007984 161.0
WH2_k127_1892276_0 Aldehyde dehydrogenase family K22187 - - 9.33e-218 679.0
WH2_k127_1892276_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 446.0
WH2_k127_1892276_2 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000009467 180.0
WH2_k127_1905005_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000008274 192.0
WH2_k127_1905005_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000005426 148.0
WH2_k127_1905005_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000363 132.0
WH2_k127_1905005_3 Cold shock protein K03704 - - 0.00000000000000000000000000007311 119.0
WH2_k127_1905005_4 LVIVD repeat - - - 0.0000004251 58.0
WH2_k127_1905005_5 Catalytic activity - GO:0000003,GO:0007276,GO:0007283,GO:0008150,GO:0019953,GO:0022414,GO:0032501,GO:0032504,GO:0044703,GO:0048232,GO:0048609,GO:0051704 - 0.000001619 54.0
WH2_k127_1940456_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 473.0
WH2_k127_1940456_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 342.0
WH2_k127_1940456_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000001036 89.0
WH2_k127_1961514_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 396.0
WH2_k127_1961514_1 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 363.0
WH2_k127_1961514_2 - - - - 0.00000000000000000000000000000000000000000000000004204 189.0
WH2_k127_1961514_3 Cold shock protein domain K03704 - - 0.0000000000000000000000000000003372 128.0
WH2_k127_1961514_4 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000003731 124.0
WH2_k127_1988888_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 592.0
WH2_k127_2096556_0 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 607.0
WH2_k127_2096556_1 Amidohydrolase K07045 - - 0.000000000000000000000000007313 112.0
WH2_k127_2106113_0 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.0000000000000000000001593 106.0
WH2_k127_2106113_2 peptidase S1 and S6, chymotrypsin Hap - - - 0.00006729 48.0
WH2_k127_2106113_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0005617 48.0
WH2_k127_2108654_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1237.0
WH2_k127_2108654_1 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000001096 230.0
WH2_k127_2112335_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 505.0
WH2_k127_2112335_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.000000000000000000000000000001558 121.0
WH2_k127_2115550_0 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 316.0
WH2_k127_2115550_1 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000005083 192.0
WH2_k127_2115550_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000005043 165.0
WH2_k127_2115550_3 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000000000001244 142.0
WH2_k127_2115550_4 TonB C terminal K03832 - - 0.00000000000000000000000000005844 134.0
WH2_k127_2125975_0 - - - - 0.00000000000000000000000000000000000000000000000000001743 196.0
WH2_k127_2125975_1 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000001643 118.0
WH2_k127_2125975_2 Transcriptional regulator antitoxin MazE K07172 - - 0.000000000000000000948 88.0
WH2_k127_2128721_0 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 437.0
WH2_k127_2128721_1 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 395.0
WH2_k127_2128721_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 324.0
WH2_k127_2128721_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001862 273.0
WH2_k127_2128721_4 Peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000001096 192.0
WH2_k127_2128721_5 lipase activity K15349 - - 0.0000000000000000000000000000000000000000000005996 185.0
WH2_k127_2128721_6 - - - - 0.0000000000000001481 90.0
WH2_k127_2155282_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 411.0
WH2_k127_2155282_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000001047 80.0
WH2_k127_2156444_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 551.0
WH2_k127_2156444_1 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000001147 114.0
WH2_k127_2157140_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1159.0
WH2_k127_2157140_1 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000001333 105.0
WH2_k127_2157140_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000002763 70.0
WH2_k127_2163525_0 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001172 280.0
WH2_k127_2163525_1 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000002818 143.0
WH2_k127_2193309_0 - - - - 5e-324 1028.0
WH2_k127_2193309_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000001818 162.0
WH2_k127_2193309_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000001699 167.0
WH2_k127_2193309_3 Tryptophan-rich sensory protein K05770 - - 0.0000000000000000000000000000000000000000362 169.0
WH2_k127_2193309_4 metal-binding protein - - - 0.000000000000000000000000000000000000001046 153.0
WH2_k127_2193309_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000002535 160.0
WH2_k127_2193309_6 Divergent 4Fe-4S mono-cluster - - - 0.0000000000000000009233 89.0
WH2_k127_2193309_7 bleomycin resistance protein K01759 - 4.4.1.5 0.00000000000000004771 82.0
WH2_k127_2193309_8 - - - - 0.00000000000504 70.0
WH2_k127_2193309_9 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000001548 65.0
WH2_k127_2205406_0 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 328.0
WH2_k127_2205406_1 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000003668 224.0
WH2_k127_2205406_2 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000003443 181.0
WH2_k127_2205406_3 WD domain, G-beta repeat K02180 - - 0.0000000000006958 70.0
WH2_k127_2226352_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 556.0
WH2_k127_2226352_1 4Fe-4S binding domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 357.0
WH2_k127_2226352_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000002583 196.0
WH2_k127_2226352_3 PFAM FAD binding domain K11472 - - 0.000000000000000000000000000000000001467 160.0
WH2_k127_2226352_4 ATP-dependent protease La (LON) substrate-binding domain K01338 - 3.4.21.53 0.0000000000000000000000000000000006206 139.0
WH2_k127_2226352_5 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.0001282 51.0
WH2_k127_2232637_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009879 242.0
WH2_k127_2232637_1 - - - - 0.00000000000000000000000000000000000282 151.0
WH2_k127_2264273_0 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 428.0
WH2_k127_2264273_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 399.0
WH2_k127_2264273_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 315.0
WH2_k127_2264273_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000002122 223.0
WH2_k127_2264273_5 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0001273 45.0
WH2_k127_2270268_0 Glutamate formimidoyltransferase K00603,K13990 - 2.1.2.5,4.3.1.4 3.8e-235 739.0
WH2_k127_2270268_1 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 304.0
WH2_k127_2270268_2 - - - - 0.000000000000000000000000000000000000000000001831 179.0
WH2_k127_2280443_0 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 352.0
WH2_k127_2280443_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000002386 262.0
WH2_k127_2280443_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000003571 110.0
WH2_k127_2326782_0 nitrous-oxide reductase activity K00376,K02275 GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 4.351e-308 957.0
WH2_k127_2326782_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000009084 235.0
WH2_k127_2326782_2 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000000000000000000000000000000000000000001925 206.0
WH2_k127_2326782_3 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000009832 158.0
WH2_k127_2326782_4 Cytochrome c - - - 0.0000000000000000000000000000000009349 136.0
WH2_k127_2326782_5 Transcriptional regulator - - - 0.0000000000000000000000000000209 121.0
WH2_k127_2328860_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 577.0
WH2_k127_2328860_1 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 517.0
WH2_k127_2328860_10 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000006193 182.0
WH2_k127_2328860_11 Cytochrome c - - - 0.0000000000000000000000000000000000000000000003562 184.0
WH2_k127_2328860_12 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000006587 166.0
WH2_k127_2328860_13 PTS system sorbose subfamily IIB component K19507 - - 0.00000000000000000000000000000000000000002064 163.0
WH2_k127_2328860_14 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000002173 136.0
WH2_k127_2328860_15 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000004364 150.0
WH2_k127_2328860_16 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.00000000000000000000000000000002249 139.0
WH2_k127_2328860_17 PTS system sorbose-specific iic component K02795 - - 0.000000000000000000000012 110.0
WH2_k127_2328860_18 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000003787 106.0
WH2_k127_2328860_19 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000002687 105.0
WH2_k127_2328860_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 475.0
WH2_k127_2328860_20 Regulatory protein, FmdB family - - - 0.00000000000000000002267 94.0
WH2_k127_2328860_21 phosphoenolpyruvate-dependent sugar phosphotransferase system K02793 - 2.7.1.191 0.00002668 51.0
WH2_k127_2328860_22 Sigma 54 modulation/S30EA ribosomal protein C terminus K05808 - - 0.0001622 48.0
WH2_k127_2328860_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 419.0
WH2_k127_2328860_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 374.0
WH2_k127_2328860_5 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 388.0
WH2_k127_2328860_6 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 356.0
WH2_k127_2328860_7 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 345.0
WH2_k127_2328860_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 314.0
WH2_k127_2328860_9 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000002429 202.0
WH2_k127_234761_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.771e-208 659.0
WH2_k127_234761_1 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 6.37e-207 656.0
WH2_k127_234761_10 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000001374 122.0
WH2_k127_234761_11 molybdopterin-guanine dinucleotide biosynthesis protein K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000001719 107.0
WH2_k127_234761_12 - - - - 0.000000000000000004466 93.0
WH2_k127_234761_13 CHAP domain - - - 0.00009947 54.0
WH2_k127_234761_2 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 473.0
WH2_k127_234761_3 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 327.0
WH2_k127_234761_4 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 336.0
WH2_k127_234761_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000842 180.0
WH2_k127_234761_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000001604 183.0
WH2_k127_234761_7 diguanylate cyclase - - - 0.0000000000000000000000000000000000001397 156.0
WH2_k127_234761_8 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000209 133.0
WH2_k127_234761_9 CoA binding domain K06929 - - 0.0000000000000000000000000000003762 136.0
WH2_k127_2357044_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 355.0
WH2_k127_2357044_1 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 294.0
WH2_k127_2357044_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008793 263.0
WH2_k127_2357044_3 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000001876 250.0
WH2_k127_2357044_4 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001359 246.0
WH2_k127_2357044_5 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000396 237.0
WH2_k127_2357044_6 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001377 233.0
WH2_k127_2357044_7 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000002669 165.0
WH2_k127_2357044_8 - - - - 0.0000000000000000000000000000000003521 137.0
WH2_k127_2357044_9 Cold shock K03704 - - 0.000000000000000000000000000000001362 132.0
WH2_k127_240145_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 6.943e-279 882.0
WH2_k127_240145_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000459 211.0
WH2_k127_240145_2 Protein of unknown function (DUF502) - - - 0.00000000001794 66.0
WH2_k127_240145_3 Selenoprotein, putative - - - 0.0000004386 55.0
WH2_k127_2411261_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 326.0
WH2_k127_2411261_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001879 278.0
WH2_k127_2411261_2 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000457 231.0
WH2_k127_2411261_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000004037 145.0
WH2_k127_2411261_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000002673 100.0
WH2_k127_2411261_5 Transcription factor zinc-finger K09981 - - 0.0000000001555 72.0
WH2_k127_2434142_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 1.79e-321 1024.0
WH2_k127_2434142_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 2.808e-256 808.0
WH2_k127_2434142_10 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 311.0
WH2_k127_2434142_11 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000517 216.0
WH2_k127_2434142_12 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000366 207.0
WH2_k127_2434142_13 - - - - 0.0000000000000000000000000000000008572 140.0
WH2_k127_2434142_14 endonuclease activity - - - 0.000000000000000000000000000000001096 134.0
WH2_k127_2434142_15 Predicted integral membrane protein (DUF2269) - - - 0.0000000000000000000000000000008392 127.0
WH2_k127_2434142_16 transcriptional regulator K22491 - - 0.0000000000000000000000000006707 128.0
WH2_k127_2434142_17 Tellurite resistance protein TehB - - - 0.00000000000000000000006319 106.0
WH2_k127_2434142_18 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000001225 104.0
WH2_k127_2434142_19 binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000002675 88.0
WH2_k127_2434142_2 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 9.168e-221 715.0
WH2_k127_2434142_20 Receptor family ligand binding region K01999 - - 0.00000000000000002337 96.0
WH2_k127_2434142_3 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 552.0
WH2_k127_2434142_4 Sodium:dicarboxylate symporter family K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 497.0
WH2_k127_2434142_5 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 457.0
WH2_k127_2434142_6 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 450.0
WH2_k127_2434142_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 369.0
WH2_k127_2434142_8 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 333.0
WH2_k127_2434142_9 tRNA synthetases class I (E and Q), catalytic domain K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 313.0
WH2_k127_2436969_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 548.0
WH2_k127_2436969_1 transcriptional regulator - - - 0.00000000000000000000001301 110.0
WH2_k127_2436969_2 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.000000000000000000007456 93.0
WH2_k127_2439512_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 542.0
WH2_k127_2439512_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 419.0
WH2_k127_2439512_2 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 323.0
WH2_k127_2450395_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 2.447e-279 871.0
WH2_k127_2450395_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.061e-201 634.0
WH2_k127_2450395_2 Belongs to the peptidase M50B family K06402 - - 0.0000000000000000000000000000000000000001871 156.0
WH2_k127_2450395_3 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000002955 70.0
WH2_k127_2494857_0 Methyltransferase small domain K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000003795 182.0
WH2_k127_2494857_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000001215 153.0
WH2_k127_2494857_2 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000000000000006364 84.0
WH2_k127_2521266_0 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 340.0
WH2_k127_2521266_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 324.0
WH2_k127_2521266_2 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000003387 272.0
WH2_k127_2521266_3 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000001568 188.0
WH2_k127_2521266_4 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000001041 109.0
WH2_k127_252223_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 532.0
WH2_k127_2533932_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.615e-300 937.0
WH2_k127_2533932_1 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 545.0
WH2_k127_2533932_2 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 422.0
WH2_k127_2533932_3 Hsp70 protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000005169 235.0
WH2_k127_2533932_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000003101 196.0
WH2_k127_2533932_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000005214 126.0
WH2_k127_2533932_6 Peptidase family M50 K11749 - - 0.0000000000000000000007396 97.0
WH2_k127_255021_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1169.0
WH2_k127_255021_1 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 379.0
WH2_k127_255021_2 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000006431 240.0
WH2_k127_255021_3 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000002918 220.0
WH2_k127_255021_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000001415 180.0
WH2_k127_255021_5 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000004716 173.0
WH2_k127_255021_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000001036 138.0
WH2_k127_255021_7 protein secretion K21449 - - 0.00000000000000000000001813 106.0
WH2_k127_255021_8 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000323 94.0
WH2_k127_255021_9 Periplasmic binding protein K02016 - - 0.000000000004038 72.0
WH2_k127_2560852_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 345.0
WH2_k127_2560852_1 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 340.0
WH2_k127_2560852_2 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 295.0
WH2_k127_2600494_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 330.0
WH2_k127_2600494_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000259 167.0
WH2_k127_2600494_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639,K20967 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0040007,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22,4.6.1.17 0.000000000000000000000000000000000000002548 148.0
WH2_k127_2605233_0 PFAM Bile acid sodium symporter K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 490.0
WH2_k127_2605233_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 397.0
WH2_k127_2605233_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000004564 179.0
WH2_k127_2605233_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000001151 115.0
WH2_k127_2648695_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 482.0
WH2_k127_2648695_1 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 416.0
WH2_k127_2648695_2 Outer membrane lipoprotein K05807 - - 0.0000000000000000000000000000000000000000711 162.0
WH2_k127_2648695_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000001226 144.0
WH2_k127_2648695_4 TPR repeat - - - 0.00004194 56.0
WH2_k127_2652027_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000003144 192.0
WH2_k127_2652027_1 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.0000000000000000000000000000001122 134.0
WH2_k127_2652027_2 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000008425 123.0
WH2_k127_2707105_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 8.421e-244 763.0
WH2_k127_2707105_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 591.0
WH2_k127_2707105_10 PQQ-like domain - - - 0.0000000000002336 75.0
WH2_k127_2707105_11 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.00000008995 64.0
WH2_k127_2707105_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 506.0
WH2_k127_2707105_3 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 420.0
WH2_k127_2707105_4 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 366.0
WH2_k127_2707105_5 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 340.0
WH2_k127_2707105_6 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000002111 239.0
WH2_k127_2707105_7 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000002287 233.0
WH2_k127_2707105_8 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000003986 179.0
WH2_k127_2707105_9 Zinc finger domain - - - 0.000000000000000005467 95.0
WH2_k127_2713264_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 6.221e-233 762.0
WH2_k127_2713264_1 Sodium/calcium exchanger protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 527.0
WH2_k127_2713264_10 Cytochrome c - - - 0.000000000000000000000000000000000000000000001864 177.0
WH2_k127_2713264_11 - - - - 0.00000000000000000000000000000000000000005323 158.0
WH2_k127_2713264_12 - - - - 0.0000000000000000000000000000000001575 148.0
WH2_k127_2713264_13 DUF218 domain - - - 0.000000000000000000000000000000002907 136.0
WH2_k127_2713264_14 - - - - 0.000000000000000000000000002341 116.0
WH2_k127_2713264_15 - - - - 0.00000000000000000007001 103.0
WH2_k127_2713264_16 META domain K09914 - - 0.000000000000001997 82.0
WH2_k127_2713264_17 - - - - 0.0000000000001313 78.0
WH2_k127_2713264_19 - - - - 0.000001933 52.0
WH2_k127_2713264_2 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 489.0
WH2_k127_2713264_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 466.0
WH2_k127_2713264_4 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 410.0
WH2_k127_2713264_5 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 325.0
WH2_k127_2713264_6 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005306 270.0
WH2_k127_2713264_7 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000009654 236.0
WH2_k127_2713264_8 VIT family - - - 0.0000000000000000000000000000000000000000000000000000005089 200.0
WH2_k127_2713264_9 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000006045 186.0
WH2_k127_2732944_0 COG0493 NADPH-dependent glutamate synthase beta chain and related K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 492.0
WH2_k127_2732944_1 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000006707 272.0
WH2_k127_2732944_2 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000003364 229.0
WH2_k127_2799452_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 352.0
WH2_k127_2815992_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 465.0
WH2_k127_2815992_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 445.0
WH2_k127_2815992_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 411.0
WH2_k127_2815992_3 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 362.0
WH2_k127_2815992_4 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000003899 165.0
WH2_k127_2815992_5 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000001289 147.0
WH2_k127_2815992_6 4 iron, 4 sulfur cluster binding K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000001649 142.0
WH2_k127_2815992_7 Protein of unknown function (DUF2490) - - - 0.0000002951 60.0
WH2_k127_2815992_8 Peptidase family M1 domain K01256 - 3.4.11.2 0.0001312 53.0
WH2_k127_2821074_0 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 542.0
WH2_k127_2821074_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 375.0
WH2_k127_2821074_2 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000002135 185.0
WH2_k127_2821074_3 Aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 0.00000000000029 69.0
WH2_k127_2845327_0 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 410.0
WH2_k127_2845327_1 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 325.0
WH2_k127_2845327_2 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000003328 222.0
WH2_k127_2845327_3 ABC transporter K02003 - - 0.000000000000005421 75.0
WH2_k127_2908701_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 6.766e-210 687.0
WH2_k127_2908701_1 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 2.402e-207 652.0
WH2_k127_2908701_2 Malate synthase K01638 - 2.3.3.9 4.306e-207 657.0
WH2_k127_2908701_3 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 418.0
WH2_k127_2908701_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 383.0
WH2_k127_2908701_5 - - - - 0.000000000000000000000000000000000000000000000000000003088 203.0
WH2_k127_2908701_6 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000001107 190.0
WH2_k127_2908701_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000001784 119.0
WH2_k127_2931477_0 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 365.0
WH2_k127_2931477_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 334.0
WH2_k127_2931477_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000001995 174.0
WH2_k127_2931477_3 Domain of unknown function (DUF4321) - - - 0.000000000000000000000002111 108.0
WH2_k127_2931477_4 Tetratricopeptide repeat - - - 0.000000000000003155 89.0
WH2_k127_2931477_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000001036 78.0
WH2_k127_2931477_6 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0003189 45.0
WH2_k127_297581_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.533e-257 814.0
WH2_k127_297581_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 307.0
WH2_k127_297581_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000008472 192.0
WH2_k127_297581_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000001268 159.0
WH2_k127_297581_4 Domain of unknown function (DUF4403) - - - 0.0000000000000000000002637 103.0
WH2_k127_297581_5 Domain of unknown function (DUF4136) - - - 0.0000691 53.0
WH2_k127_2989093_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 422.0
WH2_k127_2989093_1 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000005236 136.0
WH2_k127_2989093_2 Domain of unknown function (DUF4440) - - - 0.0000009386 59.0
WH2_k127_3018015_0 DNA restriction-modification system - - - 0.000000000000000000000000000000000000000000000000000000000000001947 237.0
WH2_k127_3018015_1 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000002038 166.0
WH2_k127_3018015_2 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.0000000000000006585 82.0
WH2_k127_3042370_0 Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 414.0
WH2_k127_3042370_1 DinB family - - - 0.000000000000000000000000000000709 133.0
WH2_k127_3042370_2 TfoX N-terminal domain - - - 0.00000000000000000000000000002587 119.0
WH2_k127_3042370_3 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000003117 81.0
WH2_k127_3042370_4 COG1226 Kef-type K transport systems K10716 - - 0.000000000001102 75.0
WH2_k127_3046975_0 AcrB/AcrD/AcrF family K03296 - - 7.867e-292 919.0
WH2_k127_3093405_0 deoxyribose-phosphate aldolase activity K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 471.0
WH2_k127_3093405_1 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000009649 265.0
WH2_k127_3093405_2 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00138 - 1.2.1.3,1.2.1.8 0.000000000000000000001403 96.0
WH2_k127_3116877_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 560.0
WH2_k127_3116877_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 549.0
WH2_k127_3116877_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006,K22424 - 2.7.3.13,2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 443.0
WH2_k127_3125703_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 299.0
WH2_k127_3125703_1 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000006766 179.0
WH2_k127_3125703_2 PAS domain - - - 0.000000000000000000000005465 117.0
WH2_k127_3125703_3 Amylo-alpha-1,6-glucosidase - - - 0.00000001957 68.0
WH2_k127_3142502_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000071 213.0
WH2_k127_3142502_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000001849 67.0
WH2_k127_3183838_0 Multicopper oxidase K00368,K22348 - 1.16.3.3,1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 423.0
WH2_k127_3183838_1 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 327.0
WH2_k127_3183838_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 315.0
WH2_k127_3183838_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 302.0
WH2_k127_3216683_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 342.0
WH2_k127_3216683_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 330.0
WH2_k127_3216683_2 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 306.0
WH2_k127_3216683_3 negative regulation of phosphate transmembrane transport K02039 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000001129 246.0
WH2_k127_3216683_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000008427 202.0
WH2_k127_3216683_5 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000009668 168.0
WH2_k127_3245482_0 Elongation factor G, domain IV K02355 - - 1.278e-197 631.0
WH2_k127_3245482_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000000000000000000000000003743 158.0
WH2_k127_3245482_2 BFD-like [2Fe-2S] binding domain - - - 0.000000063 60.0
WH2_k127_3248718_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 551.0
WH2_k127_3248718_1 Phage terminase large subunit (GpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 503.0
WH2_k127_3248718_10 Psort location Cytoplasmic, score - - - 0.0003843 49.0
WH2_k127_3248718_2 Formyl transferase K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000002295 226.0
WH2_k127_3248718_3 Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0) K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000003707 185.0
WH2_k127_3248718_4 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000002811 167.0
WH2_k127_3248718_5 MerR, DNA binding K19591 - - 0.000000000000000000000000000000002791 132.0
WH2_k127_3248718_6 MerT mercuric transport protein K08363 - - 0.0000000000003333 74.0
WH2_k127_3248718_7 - - - - 0.000002973 55.0
WH2_k127_3248718_8 mercury ion transmembrane transporter activity K08364 - - 0.000008726 53.0
WH2_k127_325706_0 - - - - 0.000000000000000000000000000000000000000000004535 171.0
WH2_k127_325706_1 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000002511 169.0
WH2_k127_325706_2 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000002785 151.0
WH2_k127_327648_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.52e-241 759.0
WH2_k127_3293438_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 382.0
WH2_k127_3293438_1 secondary active sulfate transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 332.0
WH2_k127_3293438_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K00950,K01633 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003161 261.0
WH2_k127_3293438_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000505 197.0
WH2_k127_3293438_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000008654 119.0
WH2_k127_3300216_0 PFAM Glycosyl transferase family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 351.0
WH2_k127_3300216_1 metal-dependent phosphohydrolase, HD sub domain K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000002178 236.0
WH2_k127_3300216_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000003586 197.0
WH2_k127_3300216_3 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000003451 197.0
WH2_k127_3300216_4 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000005617 140.0
WH2_k127_3300216_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000162 80.0
WH2_k127_3300216_6 Histidine kinase - - - 0.0000000000001174 83.0
WH2_k127_3300216_7 Bacterial regulatory protein, Fis family K07713 - - 0.00001114 53.0
WH2_k127_3300216_8 Type II transport protein GspH K02457 - - 0.0005002 48.0
WH2_k127_3306053_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 623.0
WH2_k127_3306053_1 Bacterial Ig-like domain 2 - - - 0.0000000002508 72.0
WH2_k127_3310872_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.173e-254 794.0
WH2_k127_3310872_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 304.0
WH2_k127_3310872_2 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001121 252.0
WH2_k127_3310872_3 CcmB protein K02194 - - 0.0000000000000000000000000000000000000000000000000000000002097 212.0
WH2_k127_3310872_4 water channel activity K02440,K06188,K09874 - - 0.000000000000000000000000000000000000000000000000000000001356 208.0
WH2_k127_3310872_5 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000002877 187.0
WH2_k127_3310872_6 Member of the two-component regulatory system AtoS AtoC. In the presence of acetoacetate, AtoS AtoC stimulates the expression of the atoDAEB operon, leading to short chain fatty acid catabolism and activation of the poly-(R)-3-hydroxybutyrate (cPHB) biosynthetic pathway. Also induces the operon in response to spermidine. Involved in the regulation of motility and chemotaxis, via transcriptional induction of the flagellar regulon. AtoC acts by binding directly to the promoter region of the target genes. In addition to its role as a transcriptional regulator, functions as a post- translational regulator that inhibits polyamine biosynthesis via regulation of ornithine decarboxylase (ODC) K02481,K07714 GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000001624 93.0
WH2_k127_3310872_7 STAS domain K04749 - - 0.000004518 54.0
WH2_k127_3354380_0 PFAM ABC transporter transmembrane region K06147,K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004552 274.0
WH2_k127_3354380_1 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002016 273.0
WH2_k127_3354380_2 Arylsulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000001716 160.0
WH2_k127_3373014_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 383.0
WH2_k127_3373014_1 Sporulation related domain - - - 0.0000000000000000000000000000000000003606 157.0
WH2_k127_3373014_2 Involved in the tonB-independent uptake of proteins - - - 0.0003504 44.0
WH2_k127_3382921_0 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 577.0
WH2_k127_3382921_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 384.0
WH2_k127_3382921_2 Zn-dependent protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 355.0
WH2_k127_3382921_3 Rhomboid family - - - 0.0000000000000000000000000000000000002028 153.0
WH2_k127_3385849_0 Beta-eliminating lyase K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 487.0
WH2_k127_3385849_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000735 202.0
WH2_k127_3385849_2 TIGRFAM M6 family metalloprotease domain - - - 0.00000000000000000000000000000000501 147.0
WH2_k127_3452828_0 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 407.0
WH2_k127_3452828_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 334.0
WH2_k127_3452828_10 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000601 43.0
WH2_k127_3452828_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005959 290.0
WH2_k127_3452828_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000002225 175.0
WH2_k127_3452828_4 Chemotaxis signal transduction protein K03408 - - 0.000000000000000000000000000000005251 133.0
WH2_k127_3452828_5 - - - - 0.00000000000000000000000000000003737 139.0
WH2_k127_3452828_6 Two component signalling adaptor domain K03408 - - 0.000000009632 63.0
WH2_k127_3483469_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 7.947e-307 955.0
WH2_k127_3490115_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 616.0
WH2_k127_3490115_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 351.0
WH2_k127_3490115_10 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000007971 145.0
WH2_k127_3490115_11 Electron transport protein SCO1 SenC K07152 - - 0.00000000000001912 88.0
WH2_k127_3490115_12 - - - - 0.00000000000004565 78.0
WH2_k127_3490115_13 - - - - 0.00000000004933 71.0
WH2_k127_3490115_14 - - - - 0.0002323 46.0
WH2_k127_3490115_2 Phospholipase D. Active site motifs. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 342.0
WH2_k127_3490115_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 311.0
WH2_k127_3490115_4 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 313.0
WH2_k127_3490115_5 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002178 279.0
WH2_k127_3490115_6 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000008135 252.0
WH2_k127_3490115_7 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000006295 224.0
WH2_k127_3490115_8 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000007061 201.0
WH2_k127_3490115_9 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000001463 188.0
WH2_k127_3532951_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.269e-264 824.0
WH2_k127_3532951_1 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 367.0
WH2_k127_3532951_2 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 332.0
WH2_k127_3532951_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000199 240.0
WH2_k127_3532951_4 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000009697 177.0
WH2_k127_3532951_5 - - - - 0.0000000000000000000000000000000000000000008892 173.0
WH2_k127_3532951_6 Lipopolysaccharide-assembly, LptC-related - - - 0.000000000000004294 84.0
WH2_k127_3532951_7 Multicopper oxidase K22348 - 1.16.3.3 0.00000001061 59.0
WH2_k127_3540144_0 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 416.0
WH2_k127_3540144_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 312.0
WH2_k127_3540144_2 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001511 279.0
WH2_k127_3540144_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000003767 268.0
WH2_k127_3540144_4 - - - - 0.0000000009324 70.0
WH2_k127_3540144_5 - - - - 0.0000003782 60.0
WH2_k127_3570499_0 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002735 281.0
WH2_k127_3570499_1 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000007013 221.0
WH2_k127_3570499_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000162 149.0
WH2_k127_363125_0 Bacterial dnaA protein K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 412.0
WH2_k127_363125_1 Small GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002486 277.0
WH2_k127_363125_2 PFAM Roadblock LC7 family protein - - - 0.0000006146 59.0
WH2_k127_3634847_0 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 313.0
WH2_k127_3634847_1 pilus organization - - - 0.000000000000000000000000000000000000000005709 165.0
WH2_k127_3634847_2 usher protein - - - 0.000000000000000000000000000000003225 150.0
WH2_k127_3634847_4 Virulence factor BrkB K07058 - - 0.000000000000000000000001882 117.0
WH2_k127_3634847_5 YtxH-like protein - - - 0.0000000007439 66.0
WH2_k127_3664762_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 448.0
WH2_k127_3664762_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000006496 226.0
WH2_k127_3664762_2 Bacterial transcriptional repressor C-terminal K09017 - - 0.00000000000000000000000000000000000000000001861 169.0
WH2_k127_3664762_3 Biotin-lipoyl like K03543 - - 0.00000000000000000000005964 104.0
WH2_k127_3691380_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000005524 216.0
WH2_k127_3691380_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000001261 192.0
WH2_k127_3691380_2 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000005773 120.0
WH2_k127_3698229_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1566.0
WH2_k127_3698229_1 UDP binding domain K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 575.0
WH2_k127_3698229_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 454.0
WH2_k127_3698229_3 O-acyltransferase activity K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 267.0
WH2_k127_3698229_4 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000005616 256.0
WH2_k127_3698229_5 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000002958 233.0
WH2_k127_3698229_6 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000128 156.0
WH2_k127_3779732_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 364.0
WH2_k127_3779732_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002686 244.0
WH2_k127_3779732_2 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000118 184.0
WH2_k127_3779732_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000005524 140.0
WH2_k127_3779732_4 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000005319 131.0
WH2_k127_3779732_5 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000003605 83.0
WH2_k127_3779732_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0001189 50.0
WH2_k127_3841862_0 LVIVD repeat - - - 6.193e-271 858.0
WH2_k127_3841862_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 466.0
WH2_k127_3841862_2 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 357.0
WH2_k127_3841862_3 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000006797 239.0
WH2_k127_3841862_4 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000000000000000000000000000003252 200.0
WH2_k127_3841862_5 Ketosteroid K06893 - - 0.0000000000000000000000000000000000000000000000000000008162 197.0
WH2_k127_3841862_6 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000002039 186.0
WH2_k127_3841862_7 NmrA-like family - - - 0.0000000000000000000000000000000000000003685 161.0
WH2_k127_3851406_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 383.0
WH2_k127_3851406_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000009415 271.0
WH2_k127_3851406_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000004255 55.0
WH2_k127_3851406_3 peptidyl-tyrosine sulfation - - - 0.00007101 55.0
WH2_k127_3863092_0 Natural resistance-associated macrophage protein K03322 - - 6.42e-200 632.0
WH2_k127_3863092_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 602.0
WH2_k127_3863092_2 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008217 287.0
WH2_k127_3863092_3 peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000004587 261.0
WH2_k127_3863092_4 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000001524 240.0
WH2_k127_3863092_5 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000000000002951 194.0
WH2_k127_3863092_6 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000004742 166.0
WH2_k127_3863092_7 NUDIX domain - - - 0.00000000000000000000000000000000000002971 150.0
WH2_k127_3863092_8 ketosteroid isomerase - - - 0.00000000000000004417 88.0
WH2_k127_3863092_9 repeat-containing protein - - - 0.0000339 57.0
WH2_k127_3869750_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 379.0
WH2_k127_3869750_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000009561 142.0
WH2_k127_3869750_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0002622 49.0
WH2_k127_3885482_0 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000007476 201.0
WH2_k127_3885482_1 Peptidase M56 - - - 0.00000000000000000000000002681 124.0
WH2_k127_3885482_2 PFAM Uncharacterised protein family (UPF0164) - - - 0.00000000000000000000002267 113.0
WH2_k127_3888750_0 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 419.0
WH2_k127_3888750_1 C-terminus of AA_permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 334.0
WH2_k127_3888750_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006263 292.0
WH2_k127_3888750_3 Iron-sulphur cluster biosynthesis - - - 0.000000000000000000000000000000000000003362 156.0
WH2_k127_3888750_4 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.00000000000000000000000000000001015 147.0
WH2_k127_3888750_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00001815 49.0
WH2_k127_3939579_0 Atp-dependent helicase - - - 4.068e-255 807.0
WH2_k127_3939579_1 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 422.0
WH2_k127_3939579_2 - - - - 0.000000000000000000000000000000004872 148.0
WH2_k127_3939579_3 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000002361 129.0
WH2_k127_3939579_4 Thioesterase superfamily K07107 - - 0.000000000000000000000616 108.0
WH2_k127_3939579_5 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0000007867 57.0
WH2_k127_3939579_6 Bacterial regulatory proteins, tetR family - - - 0.0002859 50.0
WH2_k127_4010025_0 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 471.0
WH2_k127_4010025_1 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 455.0
WH2_k127_4010025_2 - - - - 0.0000000000000000000000000000000000000000000000000004013 198.0
WH2_k127_4010025_3 - - - - 0.0000000000000000000000008602 121.0
WH2_k127_4010025_4 Belongs to the ABC transporter superfamily K02032 - - 0.00000002256 63.0
WH2_k127_4030134_0 Belongs to the DapA family K21062 - 3.5.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 355.0
WH2_k127_4030134_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 299.0
WH2_k127_4030134_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 291.0
WH2_k127_4066288_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000006269 198.0
WH2_k127_4066288_1 - - - - 0.0000000000000000000000000001153 126.0
WH2_k127_4066288_2 Bacterial transcriptional activator domain - - - 0.00000000000000000000005113 113.0
WH2_k127_4082662_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.64e-229 723.0
WH2_k127_4082662_1 ketosteroid isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003502 291.0
WH2_k127_4082662_2 tungstate binding K15495 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005142 263.0
WH2_k127_4082662_3 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000005625 136.0
WH2_k127_4082662_4 Yip1 domain - - - 0.00000000000000000000000000009344 125.0
WH2_k127_4082662_5 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000007215 98.0
WH2_k127_4082662_6 Amidohydrolase family - - - 0.000000000001381 69.0
WH2_k127_4082662_7 Terminase RNAseH like domain K06909 - - 0.00002591 50.0
WH2_k127_4093105_0 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 492.0
WH2_k127_4093105_1 PFAM peptidase M18 aminopeptidase I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 411.0
WH2_k127_4093105_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005758 278.0
WH2_k127_4093105_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000041 245.0
WH2_k127_4093105_4 - - - - 0.000000000000000000000000000000000000000002898 161.0
WH2_k127_4093105_5 - - - - 0.0000000000000000000000000000000000000002837 152.0
WH2_k127_4093105_6 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000001802 120.0
WH2_k127_4111044_0 Pfam Sulfatase K01130 - 3.1.6.1 0.0 1423.0
WH2_k127_4111044_1 Sulfatase K01130 - 3.1.6.1 0.0 1186.0
WH2_k127_4111044_10 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 306.0
WH2_k127_4111044_11 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003536 274.0
WH2_k127_4111044_12 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002054 261.0
WH2_k127_4111044_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000002947 249.0
WH2_k127_4111044_14 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000009766 178.0
WH2_k127_4111044_15 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000001729 139.0
WH2_k127_4111044_16 Diguanylate cyclase - - - 0.000000000000000000000000003158 130.0
WH2_k127_4111044_17 - - - - 0.00000000000000000001897 100.0
WH2_k127_4111044_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.92e-246 769.0
WH2_k127_4111044_3 Protein of unknown function (DUF1214) - - - 4.827e-224 702.0
WH2_k127_4111044_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 9.052e-213 679.0
WH2_k127_4111044_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 433.0
WH2_k127_4111044_6 Cell cycle protein K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 436.0
WH2_k127_4111044_7 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 420.0
WH2_k127_4111044_8 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 384.0
WH2_k127_4111044_9 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 381.0
WH2_k127_4143481_0 domain, Protein - - - 8.345e-195 614.0
WH2_k127_4143481_1 - - - - 0.000000000000000000000002829 108.0
WH2_k127_4177245_0 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 299.0
WH2_k127_4177245_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008265 275.0
WH2_k127_4177245_2 methylamine metabolic process K15977 - - 0.000000000000000000000000000000000000000000369 162.0
WH2_k127_4177245_3 PFAM Conserved TM helix - - - 0.000000000000000000000000000000000000000842 156.0
WH2_k127_4177245_4 Multicopper oxidase K04753 - - 0.000000000000000000000000000001259 135.0
WH2_k127_4177245_5 phosphinothricin N-acetyltransferase activity K03823,K06718 - 2.3.1.178,2.3.1.183 0.00000000002712 73.0
WH2_k127_4182656_0 GNAT family acetyltransferase K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 566.0
WH2_k127_4182656_1 Mur ligase family, glutamate ligase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 425.0
WH2_k127_4204607_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 609.0
WH2_k127_4214963_0 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 344.0
WH2_k127_4214963_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000505 134.0
WH2_k127_4214963_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000003105 117.0
WH2_k127_4214963_3 Protein of unknown function, DUF481 K07283 - - 0.0000000001104 74.0
WH2_k127_4265889_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 520.0
WH2_k127_4265889_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 374.0
WH2_k127_4265889_2 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 339.0
WH2_k127_4265889_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009519 263.0
WH2_k127_4265889_4 Domain of unknown function (DUF4321) - - - 0.00000000000000004311 93.0
WH2_k127_4265889_5 cellulase activity K06882 - - 0.000000000000001078 89.0
WH2_k127_4296241_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 437.0
WH2_k127_4296241_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000005118 211.0
WH2_k127_4296241_2 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000000001128 188.0
WH2_k127_4296241_3 Binds the 23S rRNA K02909 - - 0.00000000000000000000002393 102.0
WH2_k127_4296241_4 Peptidoglycan-synthase activator LpoB - - - 0.00000002517 64.0
WH2_k127_430540_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 327.0
WH2_k127_430540_1 Oxygen tolerance - - - 0.000003798 58.0
WH2_k127_4305452_0 Protein export membrane protein - - - 0.0 1084.0
WH2_k127_4305452_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000001322 184.0
WH2_k127_4305452_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000002264 117.0
WH2_k127_4305452_3 Protein of unknown function (DUF2892) - - - 0.0000000000000000000006186 96.0
WH2_k127_4305463_0 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 481.0
WH2_k127_4305463_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 452.0
WH2_k127_4305463_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 297.0
WH2_k127_4305463_3 - K02450 - - 0.000000000000000000000000000000000000000000000000000001421 199.0
WH2_k127_4305463_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000007345 166.0
WH2_k127_4305463_5 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000001348 103.0
WH2_k127_4318719_0 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 514.0
WH2_k127_4318719_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 306.0
WH2_k127_4412493_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.694e-320 1009.0
WH2_k127_4412493_1 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 395.0
WH2_k127_4412493_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001309 306.0
WH2_k127_4412493_3 - - - - 0.0000000000000000000000000000000000000000000000000000000005718 231.0
WH2_k127_4412493_4 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000003238 205.0
WH2_k127_4412493_5 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000002185 197.0
WH2_k127_4412493_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000002298 175.0
WH2_k127_4428390_0 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 307.0
WH2_k127_4428390_1 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000005479 132.0
WH2_k127_4428390_2 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000001179 94.0
WH2_k127_4428390_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0003108 48.0
WH2_k127_4454802_0 with chaperone activity ATP-binding K03696 - - 1.488e-306 962.0
WH2_k127_4454802_1 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 402.0
WH2_k127_4454802_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000004237 153.0
WH2_k127_4454802_3 UvrB/uvrC motif K19411 - - 0.0000000000000000000000000000000005153 138.0
WH2_k127_4454802_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000008583 73.0
WH2_k127_44667_0 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 347.0
WH2_k127_44667_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000001465 142.0
WH2_k127_44667_2 peptidyl-tyrosine sulfation - - - 0.000000005732 69.0
WH2_k127_4517597_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 427.0
WH2_k127_4517597_1 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000003089 227.0
WH2_k127_4517597_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000002745 203.0
WH2_k127_4517597_3 Acetyltransferase (GNAT) domain K22479 - - 0.0000000000000000000000000000000000000000272 155.0
WH2_k127_4517597_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000001714 130.0
WH2_k127_4517597_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.000000000000000005302 87.0
WH2_k127_4517597_6 TonB-dependent Receptor Plug Domain - - - 0.0000000000000632 86.0
WH2_k127_4594758_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.406e-225 738.0
WH2_k127_4594758_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 405.0
WH2_k127_4594758_2 acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000001327 223.0
WH2_k127_4594758_3 Belongs to the glycosyl hydrolase 18 family - - - 0.000000000000000000000000000000000000000000002637 184.0
WH2_k127_4594758_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000006507 126.0
WH2_k127_4594758_5 - - - - 0.000000000000001647 85.0
WH2_k127_4594758_6 - - - - 0.00000122 57.0
WH2_k127_4632919_0 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 626.0
WH2_k127_4632919_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 509.0
WH2_k127_4632919_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 342.0
WH2_k127_4632919_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 292.0
WH2_k127_4632919_4 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000006099 86.0
WH2_k127_4632919_5 Oxidoreductase domain protein - - - 0.0003229 52.0
WH2_k127_4659295_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 2.566e-266 835.0
WH2_k127_4659295_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000003499 112.0
WH2_k127_4659295_2 Domain of unknown function (DUF5117) - - - 0.000000000000000000000000004755 116.0
WH2_k127_4659295_3 subunit of a heme lyase K02200 - - 0.00000000000000000000003824 108.0
WH2_k127_4659295_4 - - - - 0.00000000000000004064 93.0
WH2_k127_4685593_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000001997 218.0
WH2_k127_4685593_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - 0.00000000000000000000000009604 120.0
WH2_k127_4707915_0 - - - - 0.0000000000003115 82.0
WH2_k127_4707915_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000002889 53.0
WH2_k127_4710339_0 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 317.0
WH2_k127_4710339_1 PFAM Sodium calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 309.0
WH2_k127_4710339_2 - - - - 0.0000000001082 65.0
WH2_k127_4719858_0 Fibronectin type 3 domain - - - 0.0000000381 61.0
WH2_k127_4719858_1 PFAM outer membrane efflux protein K15725 - - 0.00000006927 63.0
WH2_k127_4725380_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 530.0
WH2_k127_4725380_1 - - - - 0.0000000000002614 74.0
WH2_k127_4734745_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 592.0
WH2_k127_4734745_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000007103 220.0
WH2_k127_4734745_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000005939 195.0
WH2_k127_4734745_3 Two component regulator propeller - - - 0.0000000000000000000000000000000000002094 160.0
WH2_k127_4734745_4 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000001537 80.0
WH2_k127_4734745_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000002312 73.0
WH2_k127_4734745_6 Septum formation initiator K05589 - - 0.00003797 55.0
WH2_k127_4785514_0 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 389.0
WH2_k127_4785514_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000008748 232.0
WH2_k127_4785514_2 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000002684 192.0
WH2_k127_4785514_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000006018 169.0
WH2_k127_4785514_4 Competence-damaged protein K03742 - 3.5.1.42 0.000000000000001454 79.0
WH2_k127_4785514_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000504 70.0
WH2_k127_4785514_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000002621 68.0
WH2_k127_4785514_7 - - - - 0.000000002042 68.0
WH2_k127_4800541_0 Sulfatase - - - 1.04e-288 899.0
WH2_k127_4800541_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 427.0
WH2_k127_4800541_2 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000002792 220.0
WH2_k127_4800541_3 DoxX K15977 - - 0.000000000000000000000000001047 115.0
WH2_k127_4840812_0 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 508.0
WH2_k127_4840812_1 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002632 285.0
WH2_k127_4840812_2 depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000004737 221.0
WH2_k127_4840812_3 cytochrome c oxidase K02351,K02862 - - 0.0000000000000000000000000000000000000000000000000000000004618 212.0
WH2_k127_4840812_4 Copper chaperone PCu(A)C K03619,K07152,K09796 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.0000000000000000000000000000000000000000000003149 174.0
WH2_k127_4840812_5 membrane transporter protein K07090 - - 0.0000000000000000000008627 109.0
WH2_k127_4840812_6 - - - - 0.00000000000000001766 90.0
WH2_k127_4840812_7 Copper chaperone PCu(A)C K07152,K09796 - - 0.0000000000003465 80.0
WH2_k127_4840812_8 TonB-dependent receptor - - - 0.0000001369 60.0
WH2_k127_4840812_9 Peptidase C26 K07010 - - 0.00000196 59.0
WH2_k127_4857518_0 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 2.234e-245 782.0
WH2_k127_4857518_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 449.0
WH2_k127_4857518_10 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000008263 123.0
WH2_k127_4857518_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000001372 105.0
WH2_k127_4857518_12 Predicted membrane protein (DUF2232) - - - 0.00000009705 64.0
WH2_k127_4857518_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 450.0
WH2_k127_4857518_3 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 432.0
WH2_k127_4857518_4 glycerone kinase activity K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 338.0
WH2_k127_4857518_5 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000009722 231.0
WH2_k127_4857518_6 Inhibitor of apoptosis-promoting Bax1 K06890 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000003421 227.0
WH2_k127_4857518_7 3-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000001073 219.0
WH2_k127_4857518_8 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002303 152.0
WH2_k127_4857518_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000003004 132.0
WH2_k127_4919312_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000619 258.0
WH2_k127_4919312_1 ABC transporter K02017,K15497 - 3.6.3.29,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000008772 216.0
WH2_k127_4919312_2 SMP-30/Gluconolaconase/LRE-like region - - - 0.0002358 53.0
WH2_k127_4952717_0 Phage major capsid protein E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 334.0
WH2_k127_4952717_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008968 287.0
WH2_k127_4952717_2 COG0616 periplasmic serine proteases (ClpP class) - - - 0.0000000000000000000000000000000000000000000008078 181.0
WH2_k127_4952717_3 - - - - 0.0000000000000000000000000000000000000003797 160.0
WH2_k127_4952717_4 Bacteriophage lambda head decoration protein D - - - 0.0000000000000000000000001772 114.0
WH2_k127_4952717_5 - - - - 0.0000005787 59.0
WH2_k127_5028431_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 557.0
WH2_k127_5028431_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 368.0
WH2_k127_5028431_2 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 368.0
WH2_k127_5028431_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007358 280.0
WH2_k127_5028431_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000003556 249.0
WH2_k127_5028431_5 HEAT repeats - - - 0.000000000000000000000000000000000005148 151.0
WH2_k127_5038398_0 GMC oxidoreductase - - - 3.578e-238 761.0
WH2_k127_5038398_1 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 381.0
WH2_k127_5038398_2 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000000000000000000229 164.0
WH2_k127_5038398_3 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000000000005747 112.0
WH2_k127_5038398_4 Xylose isomerase-like TIM barrel - - - 0.0001065 48.0
WH2_k127_5044560_0 HELICc2 K03722 - 3.6.4.12 2.028e-273 870.0
WH2_k127_5044560_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 508.0
WH2_k127_5044560_10 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division K20543 - - 0.000000000000000000000000000000000002928 156.0
WH2_k127_5044560_11 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000001527 139.0
WH2_k127_5044560_12 Helix-turn-helix domain - - - 0.0000000000000000000000000004107 123.0
WH2_k127_5044560_13 Protein of unknown function (DUF1569) - - - 0.000000000000000000000000008859 114.0
WH2_k127_5044560_14 - - - - 0.0000000000000000000001529 102.0
WH2_k127_5044560_15 COG NOG26965 non supervised orthologous group - - - 0.000000000000000001063 96.0
WH2_k127_5044560_16 acetyltransferase - - - 0.0000000003873 72.0
WH2_k127_5044560_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 507.0
WH2_k127_5044560_3 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 437.0
WH2_k127_5044560_4 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 411.0
WH2_k127_5044560_5 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 367.0
WH2_k127_5044560_6 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 295.0
WH2_k127_5044560_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003138 264.0
WH2_k127_5044560_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000002222 245.0
WH2_k127_5044560_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003681 237.0
WH2_k127_505403_0 protease with the C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009396 244.0
WH2_k127_505403_2 - K21449 - - 0.00000000005505 75.0
WH2_k127_5075407_0 RHS Repeat - - - 0.00000000000000000000000000001832 136.0
WH2_k127_5087048_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 547.0
WH2_k127_5087048_1 - - - - 0.00000000000000000000000000000007997 134.0
WH2_k127_5087048_2 Putative lumazine-binding - - - 0.000000000000000000000000000002619 125.0
WH2_k127_5087048_3 helix_turn_helix, Lux Regulon - - - 0.000000145 54.0
WH2_k127_510510_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 603.0
WH2_k127_510510_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000001607 259.0
WH2_k127_510510_2 Mazg nucleotide pyrophosphohydrolase K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000001831 168.0
WH2_k127_510510_3 - - - - 0.000000000000003276 79.0
WH2_k127_510510_4 - - - - 0.0000000002838 66.0
WH2_k127_5108724_0 Hsp70 protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 429.0
WH2_k127_5108724_1 rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000001958 178.0
WH2_k127_5108724_2 rod shape-determining protein MreD K03571 - - 0.00000001037 63.0
WH2_k127_5140090_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 1.426e-234 756.0
WH2_k127_5140090_1 Ftsk_gamma K03466 - - 4.852e-209 680.0
WH2_k127_5140090_10 regulation of DNA repair K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000001234 83.0
WH2_k127_5140090_2 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008589 591.0
WH2_k127_5140090_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 546.0
WH2_k127_5140090_4 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 499.0
WH2_k127_5140090_5 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000435 288.0
WH2_k127_5140090_6 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000000000004391 189.0
WH2_k127_5140090_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000002761 123.0
WH2_k127_5140090_8 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000003043 115.0
WH2_k127_5140090_9 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000004548 113.0
WH2_k127_5163705_0 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 535.0
WH2_k127_5163705_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 398.0
WH2_k127_5163705_2 - - - - 0.000000000000000000000001276 113.0
WH2_k127_5163705_3 Tetratricopeptide repeat - - - 0.00000003371 59.0
WH2_k127_5195205_0 DALR_2 K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 518.0
WH2_k127_5195205_1 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 360.0
WH2_k127_5195205_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000003008 180.0
WH2_k127_5195205_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00001727 55.0
WH2_k127_5207389_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1572.0
WH2_k127_5207389_1 AcrB/AcrD/AcrF family K15726 - - 3.733e-287 914.0
WH2_k127_5207389_10 Membrane - - - 0.00000000001711 73.0
WH2_k127_5207389_11 efflux transmembrane transporter activity K15725 - - 0.0004737 49.0
WH2_k127_5207389_2 Heavy metal translocating P-type atpase K01533 - 3.6.3.4 3.821e-222 708.0
WH2_k127_5207389_3 type ii restriction enzyme K01155 - 3.1.21.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 613.0
WH2_k127_5207389_4 COG2217 Cation transport ATPase K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 463.0
WH2_k127_5207389_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.0000000000000000000000000000000000000000000000000000000000007699 225.0
WH2_k127_5207389_6 Transcriptional regulator with HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000009447 219.0
WH2_k127_5207389_7 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000009378 167.0
WH2_k127_5207389_8 Copper amine oxidase - - - 0.000000000000000000000000000000004857 135.0
WH2_k127_5207389_9 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000003255 88.0
WH2_k127_5235443_0 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000005739 180.0
WH2_k127_5235443_1 PFAM regulatory protein TetR K09017 - - 0.0000000000000006015 86.0
WH2_k127_5235443_2 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000002177 68.0
WH2_k127_5235443_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0002596 52.0
WH2_k127_5321943_0 protein secretion by the type I secretion system K11085 - - 6.3e-235 739.0
WH2_k127_5321943_1 Thioredoxin - - - 0.000000000000000000000000000000000000000000004367 169.0
WH2_k127_5321943_2 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000001012 106.0
WH2_k127_533839_0 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 451.0
WH2_k127_533839_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 368.0
WH2_k127_533839_10 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000002815 120.0
WH2_k127_533839_2 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 327.0
WH2_k127_533839_3 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 317.0
WH2_k127_533839_4 CarboxypepD_reg-like domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003228 271.0
WH2_k127_533839_5 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000001457 239.0
WH2_k127_533839_6 PaaX-like protein K02616 - - 0.00000000000000000000000000000000000000000000000000000000000001652 226.0
WH2_k127_533839_7 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000001361 190.0
WH2_k127_533839_8 - - - - 0.0000000000000000000000000000000000000000000000004856 185.0
WH2_k127_533839_9 MaoC like domain - - - 0.0000000000000000000000000000000001121 138.0
WH2_k127_5347327_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001619 275.0
WH2_k127_5347327_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000006446 160.0
WH2_k127_5347327_2 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000000000000001377 157.0
WH2_k127_5347327_3 - - - - 0.000000000000000000007847 97.0
WH2_k127_5347327_4 - - - - 0.0002404 53.0
WH2_k127_5354166_0 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000001836 223.0
WH2_k127_5354166_1 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000001058 177.0
WH2_k127_5354166_2 PFAM Rhomboid family - - - 0.0000000000000000000000000000005663 133.0
WH2_k127_5354166_3 SnoaL-like domain - - - 0.0000002391 60.0
WH2_k127_5357181_0 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 377.0
WH2_k127_5357181_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005012 259.0
WH2_k127_5357181_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000002028 192.0
WH2_k127_5452665_0 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 477.0
WH2_k127_5452665_1 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000001407 222.0
WH2_k127_5452665_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000001894 140.0
WH2_k127_5452665_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000009902 120.0
WH2_k127_5471905_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 380.0
WH2_k127_5471905_1 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000002133 94.0
WH2_k127_5471921_0 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000003253 156.0
WH2_k127_5529442_0 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 355.0
WH2_k127_5529442_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 328.0
WH2_k127_5529442_2 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003824 282.0
WH2_k127_5529442_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000001421 207.0
WH2_k127_5529442_4 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000006799 150.0
WH2_k127_5529442_5 Transglycosylase associated protein - - - 0.000000000000000000000004499 104.0
WH2_k127_5529442_6 - - - - 0.0000000000000000008229 98.0
WH2_k127_5529442_7 - K07215 - 1.14.99.58 0.00000000000000001502 94.0
WH2_k127_5529442_8 - - - - 0.0000000118 59.0
WH2_k127_5529442_9 SnoaL-like domain - - - 0.00000003602 65.0
WH2_k127_5531250_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0000000000000000000000000000003265 139.0
WH2_k127_5531250_1 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000001908 124.0
WH2_k127_5531250_2 Putative bacterial sensory transduction regulator - - - 0.0000000000001241 75.0
WH2_k127_5531250_3 - - - - 0.00004129 50.0
WH2_k127_5544834_0 choline dehydrogenase activity K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 363.0
WH2_k127_5544834_1 Belongs to the glycosyl hydrolase 18 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004908 259.0
WH2_k127_5634466_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 368.0
WH2_k127_5634466_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 304.0
WH2_k127_5634466_10 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.00000000000335 76.0
WH2_k127_5634466_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001168 301.0
WH2_k127_5634466_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000001703 254.0
WH2_k127_5634466_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000001674 233.0
WH2_k127_5634466_5 Iron permease FTR1 K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000003418 231.0
WH2_k127_5634466_6 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000714 163.0
WH2_k127_5634466_7 Iron permease K07243 - - 0.00000000000000000000000000004687 130.0
WH2_k127_5634466_8 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000000000000001434 105.0
WH2_k127_5634466_9 ThiS family - - - 0.0000000000000002334 80.0
WH2_k127_5692616_0 B12 binding domain K00548 - 2.1.1.13 0.0 1612.0
WH2_k127_5692616_1 C4-dicarboxylate anaerobic carrier - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 495.0
WH2_k127_5692616_2 Fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 451.0
WH2_k127_5692616_3 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000006438 231.0
WH2_k127_5692616_4 YGGT family K02221 - - 0.00000000000000000000000000002693 125.0
WH2_k127_5692616_5 Belongs to the UPF0235 family K09131 - - 0.000000000000000000004861 103.0
WH2_k127_5724627_0 GMC oxidoreductase - - - 3.041e-280 878.0
WH2_k127_5724627_1 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 2.57e-196 634.0
WH2_k127_5724627_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 356.0
WH2_k127_5724627_3 Gluconate 2-dehydrogenase subunit 3 - - - 0.00000000000000000000000000000000000000000001337 183.0
WH2_k127_5760975_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 505.0
WH2_k127_5760975_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 426.0
WH2_k127_5760975_2 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000006083 88.0
WH2_k127_5810612_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 438.0
WH2_k127_5810612_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001111 261.0
WH2_k127_5810612_2 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006678 256.0
WH2_k127_5810612_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000119 226.0
WH2_k127_5810612_4 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000006489 192.0
WH2_k127_5810612_5 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000005207 184.0
WH2_k127_5810612_6 Acyltransferase - - - 0.00000000000000000000000000000000000005372 152.0
WH2_k127_5810612_7 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000001393 117.0
WH2_k127_5810612_8 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000008825 94.0
WH2_k127_5810612_9 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000005931 67.0
WH2_k127_5824603_0 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 383.0
WH2_k127_5824603_1 AAA domain K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 310.0
WH2_k127_5824603_2 COG0433 Predicted ATPase K06915 - - 0.000000000000000000002239 97.0
WH2_k127_5824935_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 355.0
WH2_k127_5824935_1 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000002684 173.0
WH2_k127_5825368_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 575.0
WH2_k127_5825368_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 576.0
WH2_k127_5825368_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 304.0
WH2_k127_5825368_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000001306 191.0
WH2_k127_5825368_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001634 151.0
WH2_k127_5825368_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000000001849 107.0
WH2_k127_5825368_6 Ribosomal protein S16 K02959 - - 0.000000000000000000006238 94.0
WH2_k127_5825368_7 - - - - 0.00000000000000000002174 103.0
WH2_k127_5825368_8 23S rRNA-intervening sequence protein - - - 0.00000000000000000005409 97.0
WH2_k127_5840956_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001195 278.0
WH2_k127_5840956_1 Trm112p-like protein K09791 - - 0.0000000000000001367 80.0
WH2_k127_5840956_2 COG NOG14600 non supervised orthologous group - - - 0.0000000000000001538 80.0
WH2_k127_5840956_3 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000003322 85.0
WH2_k127_5848680_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 4.628e-256 814.0
WH2_k127_5848680_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000006478 226.0
WH2_k127_5848680_2 outer membrane efflux protein - - - 0.0000000253 67.0
WH2_k127_5874911_0 Mechanosensitive ion channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 359.0
WH2_k127_5874911_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000001728 102.0
WH2_k127_5893004_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.067e-194 623.0
WH2_k127_5893004_1 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 494.0
WH2_k127_5893004_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 335.0
WH2_k127_5893004_3 Transglutaminase/protease-like homologues - - - 0.0000000000000009794 91.0
WH2_k127_5893004_4 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000005564 75.0
WH2_k127_5893004_5 Tetratricopeptide repeat - - - 0.0000001495 63.0
WH2_k127_5893004_6 Protein of unknown function (DUF3103) - - - 0.0000929 55.0
WH2_k127_5893177_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 600.0
WH2_k127_5893442_0 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 311.0
WH2_k127_5893442_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000126 198.0
WH2_k127_5893442_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000005152 168.0
WH2_k127_5901915_0 NAD(P) transhydrogenase beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 559.0
WH2_k127_5901915_1 ABC transporter K06020 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 528.0
WH2_k127_5901915_2 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 523.0
WH2_k127_5901915_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 437.0
WH2_k127_5901915_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000001788 143.0
WH2_k127_5901915_5 SWI complex, BAF60b domains - - - 0.00000000000000000000000001183 125.0
WH2_k127_5901915_6 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000003921 113.0
WH2_k127_5901915_7 PFAM flavin reductase domain protein, FMN-binding K13786 - 1.16.8.1 0.00000000001307 72.0
WH2_k127_5943204_0 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 316.0
WH2_k127_5965112_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 478.0
WH2_k127_5965112_1 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 293.0
WH2_k127_5965112_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000002318 72.0
WH2_k127_5965112_11 Damage-inducible protein DinB - - - 0.0002886 50.0
WH2_k127_5965112_2 N-terminal domain of galactosyltransferase K13500 - 2.4.1.175,2.4.1.226 0.000000000000000000000000000000000000000000000000000000000000000005162 235.0
WH2_k127_5965112_3 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000001502 172.0
WH2_k127_5965112_4 - - - - 0.000000000000000000000000000000000000000000000296 173.0
WH2_k127_5965112_5 Polysaccharide pyruvyl transferase - - - 0.0000000000000000000000000000000000000002347 163.0
WH2_k127_5965112_6 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000001942 154.0
WH2_k127_5965112_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000002358 143.0
WH2_k127_5965112_8 Glycosyl transferases group 1 - - - 0.000000000000000000007625 106.0
WH2_k127_5965112_9 protein conserved in bacteria K09796 - - 0.00000000000000002153 93.0
WH2_k127_5970338_0 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 418.0
WH2_k127_5970338_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000002568 240.0
WH2_k127_5970338_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K00982,K03564 - 1.11.1.15,2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000002642 190.0
WH2_k127_5970338_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000261 117.0
WH2_k127_5987202_0 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 331.0
WH2_k127_5987202_1 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 289.0
WH2_k127_5987202_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000861 275.0
WH2_k127_5987202_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000002259 236.0
WH2_k127_5987202_4 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.000000000000000000000000000000000000000000000000000253 191.0
WH2_k127_5987202_5 Export-related chaperone CsaA K06878 - - 0.00000000000000000000000000000000000000000001011 165.0
WH2_k127_5987202_6 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000154 140.0
WH2_k127_5987202_7 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000004252 132.0
WH2_k127_5987202_8 Endoribonuclease L-PSP - - - 0.000000000000000000000005414 102.0
WH2_k127_6021082_0 MacB-like periplasmic core domain - - - 5.133e-273 858.0
WH2_k127_6021082_1 efflux transmembrane transporter activity - - - 0.00000000000000000002646 93.0
WH2_k127_6080353_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 2.029e-320 989.0
WH2_k127_6080353_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000002008 210.0
WH2_k127_6080353_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000004871 199.0
WH2_k127_6080353_3 protein conserved in bacteria K09922 - - 0.0000000000000000000000000000000000000000000000005384 177.0
WH2_k127_6080353_4 - - - - 0.000000000000000000000000000001371 130.0
WH2_k127_6080353_6 - - - - 0.000000000006308 70.0
WH2_k127_6138727_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 602.0
WH2_k127_6138727_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 397.0
WH2_k127_6138727_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 291.0
WH2_k127_6138727_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000001105 118.0
WH2_k127_6138727_4 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000006336 105.0
WH2_k127_614388_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 8.98e-224 704.0
WH2_k127_614388_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 447.0
WH2_k127_614388_2 Phosphate acetyl/butaryl transferase K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 332.0
WH2_k127_614388_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006924 287.0
WH2_k127_614388_4 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000001116 119.0
WH2_k127_6147437_2 luxR family - - - 0.0000000000000002536 89.0
WH2_k127_6147437_3 - - - - 0.0000000003459 68.0
WH2_k127_6147437_4 PFAM AFG1-family ATPase K06916 - - 0.000000002592 67.0
WH2_k127_616074_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1139.0
WH2_k127_616074_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 506.0
WH2_k127_616074_2 AMIN domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 418.0
WH2_k127_616074_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000004304 126.0
WH2_k127_616074_4 - - - - 0.0000000000000000000007818 99.0
WH2_k127_616176_0 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 445.0
WH2_k127_616176_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000008912 161.0
WH2_k127_616176_2 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.000000000000000000000000000001071 129.0
WH2_k127_616176_3 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000002757 88.0
WH2_k127_618622_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000002225 226.0
WH2_k127_618622_1 diguanylate cyclase - - - 0.0000000000000000000000000000001268 142.0
WH2_k127_618622_2 HD domain - - - 0.0000000000000000000000000001574 122.0
WH2_k127_618622_3 Putative stress-induced transcription regulator - - - 0.000000000000001174 88.0
WH2_k127_618622_4 protein kinase activity - - - 0.000000003125 65.0
WH2_k127_6240533_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 420.0
WH2_k127_6240533_1 diguanylate cyclase - - - 0.000000000000000000000000000000000005278 143.0
WH2_k127_6247338_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 480.0
WH2_k127_6247338_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000001806 150.0
WH2_k127_6247338_2 PFAM Uncharacterised conserved protein UCP016719 - - - 0.000000000008022 70.0
WH2_k127_6255548_0 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 1.06e-197 652.0
WH2_k127_6255548_1 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 422.0
WH2_k127_6255548_2 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 327.0
WH2_k127_6255548_3 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 326.0
WH2_k127_6255548_4 HAMP domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 338.0
WH2_k127_6255548_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001979 281.0
WH2_k127_6255548_6 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009746 296.0
WH2_k127_6255548_7 DNA-binding transcription factor activity K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000008218 64.0
WH2_k127_6270466_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 324.0
WH2_k127_6270466_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000004326 169.0
WH2_k127_6276110_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 333.0
WH2_k127_6276110_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001233 287.0
WH2_k127_6276110_2 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000004031 266.0
WH2_k127_6276110_3 Part of the ABC transporter FtsEX involved in K09811 - - 0.000000000000000000000000000000000000000000000000007108 187.0
WH2_k127_6276110_4 Zn-dependent protease - - - 0.000009336 58.0
WH2_k127_6281617_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 4.463e-228 726.0
WH2_k127_6281617_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 548.0
WH2_k127_6283707_0 PFAM phosphoribulokinase uridine kinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000003301 261.0
WH2_k127_6283707_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000715 233.0
WH2_k127_6283707_2 - - - - 0.00000000000000000000008403 104.0
WH2_k127_6313430_0 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000000000000003186 214.0
WH2_k127_6346075_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000792 286.0
WH2_k127_6346075_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003733 260.0
WH2_k127_6346075_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000005396 234.0
WH2_k127_6346075_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000005968 179.0
WH2_k127_6353397_0 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 390.0
WH2_k127_6353397_1 Protein of unknown function DUF72 - - - 0.000000000000000000002036 100.0
WH2_k127_6353397_2 PFAM Mechanosensitive ion channel - - - 0.0001561 44.0
WH2_k127_6360431_0 Surface antigen - - - 0.00000000000000000000000000000000000000000001001 187.0
WH2_k127_6360431_1 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00001098 48.0
WH2_k127_6399029_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 437.0
WH2_k127_6399029_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000009946 174.0
WH2_k127_6399029_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000001851 170.0
WH2_k127_6399029_3 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000002889 148.0
WH2_k127_6399029_4 Glucose inhibited division protein A K21401 - 1.3.99.38 0.0000000000000000000000000001438 118.0
WH2_k127_6408394_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 376.0
WH2_k127_6408394_1 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002039 259.0
WH2_k127_6408394_2 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000003449 231.0
WH2_k127_6408394_3 CarboxypepD_reg-like domain K02014 - - 0.00000000000000000000000000000000000000000000006611 182.0
WH2_k127_6408394_4 Transcription elongation factor, N-terminal K03624 - - 0.00000000000000000000000000000000000000000004564 165.0
WH2_k127_6408394_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - 0.000000000000000000000000000000000000271 143.0
WH2_k127_6408394_6 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000009375 123.0
WH2_k127_6436525_0 AAA domain K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 357.0
WH2_k127_6436525_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 321.0
WH2_k127_6436525_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000002049 161.0
WH2_k127_6464306_0 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 351.0
WH2_k127_6464306_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000006964 167.0
WH2_k127_6464306_2 Dolichol kinase - - - 0.000000000000000000000000000000000006879 150.0
WH2_k127_6464306_3 - - - - 0.00000000000000000000000000001255 126.0
WH2_k127_6464306_4 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.000000000003384 70.0
WH2_k127_6464306_5 Putative zinc-finger - GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000006539 57.0
WH2_k127_6470347_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 477.0
WH2_k127_6470347_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 449.0
WH2_k127_6486783_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 436.0
WH2_k127_6486783_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 307.0
WH2_k127_6486783_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000005311 248.0
WH2_k127_6486783_3 HEAT repeats - - - 0.00000000000000000000000000000000000000000000004418 180.0
WH2_k127_6486783_4 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.00000000000000000000000000000000008295 137.0
WH2_k127_6486783_5 Chemotaxis sensory transducer K03406 - - 0.0000000000000000000000005013 122.0
WH2_k127_650030_0 LVIVD repeat - - - 1.107e-207 663.0
WH2_k127_650030_1 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000001665 102.0
WH2_k127_6505644_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 414.0
WH2_k127_6505644_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 354.0
WH2_k127_6505644_2 - - - - 0.0003044 52.0
WH2_k127_6519304_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 477.0
WH2_k127_6519304_1 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007272 282.0
WH2_k127_6519304_2 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004639 256.0
WH2_k127_6519304_3 Tfp pilus assembly protein FimV K00694 - 2.4.1.12 0.000000000000000000000000000000000000003635 163.0
WH2_k127_6519304_5 signal transduction histidine kinase - - - 0.00008696 53.0
WH2_k127_6521226_0 Sodium:solute symporter family - - - 2.629e-280 871.0
WH2_k127_6521226_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 609.0
WH2_k127_6521226_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000001182 210.0
WH2_k127_6521226_11 Transposase - - - 0.000001199 62.0
WH2_k127_6521226_2 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 348.0
WH2_k127_6521226_3 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 318.0
WH2_k127_6521226_4 sulfurtransferase K01011 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016782,GO:0016783,GO:0016784,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 311.0
WH2_k127_6521226_5 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008411 281.0
WH2_k127_6521226_6 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000003634 273.0
WH2_k127_6521226_7 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000959 249.0
WH2_k127_6521226_8 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000004667 253.0
WH2_k127_6521226_9 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000001131 224.0
WH2_k127_6531598_0 Putative aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005062 255.0
WH2_k127_6531598_1 domain, Protein - - - 0.00000001503 62.0
WH2_k127_657774_0 Rhodanese Homology Domain K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 549.0
WH2_k127_6585064_0 Thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001185 270.0
WH2_k127_6585064_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000003764 178.0
WH2_k127_6585064_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0000000000000000000000000000000000000000007715 160.0
WH2_k127_6585064_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000007834 164.0
WH2_k127_6585064_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000006309 88.0
WH2_k127_6585064_5 DbpA RNA binding domain K05592 - 3.6.4.13 0.00000000062 64.0
WH2_k127_660156_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 608.0
WH2_k127_660156_1 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 323.0
WH2_k127_660156_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000111 247.0
WH2_k127_660156_3 SprT-like family - - - 0.00000000000000000000000000000000000000002813 162.0
WH2_k127_660156_4 Domain of unknown function (DUF4139) - - - 0.0000000000000000000008614 99.0
WH2_k127_660156_5 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000005846 96.0
WH2_k127_6607817_0 Tetratricopeptide repeat K08884,K12132 - 2.7.11.1 1.033e-283 899.0
WH2_k127_6607817_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 598.0
WH2_k127_6607817_10 - - - - 0.00000000000000000000000000002857 124.0
WH2_k127_6607817_11 lyase activity - - - 0.000000000000000000000000003091 129.0
WH2_k127_6607817_12 - - - - 0.00000000000000000000000007831 114.0
WH2_k127_6607817_13 Protein of unknown function (DUF3995) - - - 0.0000000000000000000002537 112.0
WH2_k127_6607817_14 Protein of unknown function (DUF1761) - - - 0.0000000000004863 74.0
WH2_k127_6607817_16 - - - - 0.0001136 52.0
WH2_k127_6607817_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 506.0
WH2_k127_6607817_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001964 284.0
WH2_k127_6607817_4 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001603 270.0
WH2_k127_6607817_5 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000001306 224.0
WH2_k127_6607817_6 PFAM GCN5-related N-acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000002663 218.0
WH2_k127_6607817_7 YjbR - - - 0.0000000000000000000000000000000000000000000000006045 181.0
WH2_k127_6607817_8 DinB family - - - 0.000000000000000000000000000001122 134.0
WH2_k127_6607817_9 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000002808 129.0
WH2_k127_6624453_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 417.0
WH2_k127_6624453_1 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 426.0
WH2_k127_6624453_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 379.0
WH2_k127_6624453_3 Domain of unknown function (DUF1611_C) P-loop domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 334.0
WH2_k127_6624453_4 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 311.0
WH2_k127_6624453_5 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002196 285.0
WH2_k127_6624453_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000137 252.0
WH2_k127_6624453_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000002912 221.0
WH2_k127_6624453_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000001698 224.0
WH2_k127_6624453_9 Uncharacterized conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000559 194.0
WH2_k127_6629836_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 315.0
WH2_k127_6629836_1 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000004365 244.0
WH2_k127_6629836_2 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000002202 180.0
WH2_k127_6631633_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 8.436e-257 813.0
WH2_k127_6631633_1 ABC transporter transmembrane region K18890 - - 4.393e-199 637.0
WH2_k127_6631633_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 288.0
WH2_k127_6631633_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000006868 116.0
WH2_k127_6631633_4 integral membrane protein K07027 - - 0.00000000000000000000004412 112.0
WH2_k127_6650666_0 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 449.0
WH2_k127_6650666_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 428.0
WH2_k127_6650666_2 Belongs to the arginase family K01479,K12255 - 3.5.3.7,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001877 282.0
WH2_k127_6669954_0 ThiF family K03148,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 449.0
WH2_k127_6669954_1 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000002754 259.0
WH2_k127_6669954_2 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000005177 196.0
WH2_k127_6669954_3 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000005226 184.0
WH2_k127_6669954_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000004559 187.0
WH2_k127_6669954_5 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000747 175.0
WH2_k127_671694_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 481.0
WH2_k127_671694_1 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 302.0
WH2_k127_671694_2 - - - - 0.0000000000000000000000002472 109.0
WH2_k127_671694_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000004338 58.0
WH2_k127_6727753_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 329.0
WH2_k127_6727753_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 302.0
WH2_k127_6727753_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000003678 136.0
WH2_k127_6727753_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000002954 95.0
WH2_k127_6727753_4 Transferrin receptor-like dimerisation domain - - - 0.000007308 50.0
WH2_k127_6730728_0 FtsX-like permease family K02004 - - 1.906e-197 650.0
WH2_k127_6730728_1 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 411.0
WH2_k127_6730728_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003549 258.0
WH2_k127_6730728_3 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000004313 227.0
WH2_k127_6730728_4 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000000000000003024 173.0
WH2_k127_6730728_5 - - - - 0.00000000000000000000000000000000000000000001791 181.0
WH2_k127_6730728_6 Putative zinc- or iron-chelating domain - - - 0.000000000000000008743 94.0
WH2_k127_6733135_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000004538 205.0
WH2_k127_6763610_0 PglZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 607.0
WH2_k127_6763610_1 PFAM glycosyl transferase family 9 K02843 - - 0.0000000000000000000000000000001723 134.0
WH2_k127_6775904_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1189.0
WH2_k127_6775904_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000002863 160.0
WH2_k127_6787604_0 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 421.0
WH2_k127_6787604_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005942 280.0
WH2_k127_6787604_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000001279 174.0
WH2_k127_6796039_0 Tricorn protease homolog K08676 - - 0.000002833 58.0
WH2_k127_6830123_0 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 313.0
WH2_k127_6830123_1 4Fe-4S single cluster domain K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005467 292.0
WH2_k127_6830123_2 Glycosyl transferase family 2 K12984 - - 0.000000000000000000000000000000000000000000000000000000000000005486 226.0
WH2_k127_6830123_3 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000003137 201.0
WH2_k127_6830123_4 Aminotransferase class-V - - - 0.0000000000000000000000000000002195 132.0
WH2_k127_6830123_5 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.00000000000000000000000000001071 130.0
WH2_k127_6851854_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001203 245.0
WH2_k127_6853147_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 580.0
WH2_k127_6853147_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 547.0
WH2_k127_6853147_10 - - - - 0.00000002691 66.0
WH2_k127_6853147_11 Domain of unknown function (DUF1844) - - - 0.0001064 53.0
WH2_k127_6853147_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 530.0
WH2_k127_6853147_3 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 487.0
WH2_k127_6853147_4 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000008215 268.0
WH2_k127_6853147_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000002175 252.0
WH2_k127_6853147_6 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000009527 130.0
WH2_k127_6853147_7 - - - - 0.0000000000000000000000001825 119.0
WH2_k127_6853147_8 competence protein ComEC Rec2 K02238 - - 0.00000000000002704 85.0
WH2_k127_6874281_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 531.0
WH2_k127_6874281_1 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008307 373.0
WH2_k127_6874281_2 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000000000000000000005348 177.0
WH2_k127_6874281_3 Disulphide isomerase - - - 0.0000000000002428 81.0
WH2_k127_6891102_0 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 8.832e-272 908.0
WH2_k127_6891102_1 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 1.639e-238 751.0
WH2_k127_6891102_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 585.0
WH2_k127_6891102_3 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 576.0
WH2_k127_6891102_4 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 320.0
WH2_k127_6891102_5 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000001708 255.0
WH2_k127_6891102_6 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000006087 221.0
WH2_k127_6891102_7 PFAM amino acid permease-associated region K03294 - - 0.0000000000000000000000000000000000000000000006206 169.0
WH2_k127_6891102_8 ComEA protein K02237 - - 0.000000000000003184 84.0
WH2_k127_6909136_0 Conserved TM helix - - - 0.0000000000000000000000000000000000000000000000000000001518 202.0
WH2_k127_6909136_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000006703 138.0
WH2_k127_6920320_0 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 559.0
WH2_k127_6920320_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 394.0
WH2_k127_6920320_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 328.0
WH2_k127_6920320_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000007436 167.0
WH2_k127_6920320_4 ThiS family - - - 0.00000000000000000000000000000007745 126.0
WH2_k127_6920320_5 - - - - 0.00000000004337 74.0
WH2_k127_6920320_6 protein related to plant photosystem II stability assembly factor - - - 0.00000000005362 76.0
WH2_k127_6940919_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 408.0
WH2_k127_6940919_1 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 344.0
WH2_k127_6940919_2 Disulphide isomerase - - - 0.00000000000000000000000000000000000000001048 156.0
WH2_k127_6940919_3 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000004347 63.0
WH2_k127_6940919_4 Protein MTO1 homolog, mitochondrial K03495 GO:0000166,GO:0000959,GO:0000963,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0070525,GO:0070899,GO:0070900,GO:0071704,GO:0090304,GO:0090646,GO:0097159,GO:0140053,GO:1900864,GO:1901265,GO:1901360,GO:1901363 - 0.00000002262 55.0
WH2_k127_6951608_0 Belongs to the peptidase M16 family K07263 - - 3.416e-271 863.0
WH2_k127_6951608_1 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 616.0
WH2_k127_6951608_2 TonB dependent receptor - - - 0.00000000000000000000000001363 127.0
WH2_k127_6951608_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000007817 93.0
WH2_k127_6969820_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 4.825e-250 788.0
WH2_k127_6969820_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000001884 237.0
WH2_k127_6969820_2 - K00241 - - 0.0000000000000000000000000000000000000000000000000000000614 205.0
WH2_k127_7007748_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 313.0
WH2_k127_7007748_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 293.0
WH2_k127_7007748_2 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000005943 211.0
WH2_k127_7007748_3 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000000000000000000000000528 197.0
WH2_k127_7007748_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000209 169.0
WH2_k127_7007748_5 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000003463 108.0
WH2_k127_7007748_6 chemotaxis protein CheV K03408,K03415 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.0000000001415 69.0
WH2_k127_7016111_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 490.0
WH2_k127_7016111_1 Phosphoglucose isomerase K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 431.0
WH2_k127_7016111_2 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 323.0
WH2_k127_7016111_3 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 314.0
WH2_k127_7016111_4 Thioredoxin-like - - - 0.00000000000000000000000000000000004125 138.0
WH2_k127_7016111_5 PFAM AhpC TSA family K03564 - 1.11.1.15 0.00000000000000000005593 102.0
WH2_k127_7065122_0 CoA-substrate-specific enzyme activase - - - 0.000000006811 60.0
WH2_k127_7065122_1 PFAM Transposase DDE domain - - - 0.00000142 60.0
WH2_k127_7079480_0 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000000009661 227.0
WH2_k127_7079480_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000015 160.0
WH2_k127_7079480_2 protein kinase activity K12132 - 2.7.11.1 0.000000000000001111 89.0
WH2_k127_7079480_3 Large extracellular alpha-helical protein K12548,K13735 - - 0.0000000000007688 79.0
WH2_k127_7131528_0 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 418.0
WH2_k127_7131528_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 352.0
WH2_k127_7131528_2 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 329.0
WH2_k127_7131528_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000000001675 156.0
WH2_k127_7219375_0 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 504.0
WH2_k127_7219375_1 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000000000000000003576 240.0
WH2_k127_7219375_2 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000002806 153.0
WH2_k127_7219375_3 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.0003229 52.0
WH2_k127_7238018_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 391.0
WH2_k127_7238018_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 375.0
WH2_k127_7238018_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000001717 118.0
WH2_k127_7238018_3 Ribosomal protein L34 K02914 - - 0.00000000000000000362 84.0
WH2_k127_7238018_4 Zn-dependent protease - - - 0.00000000000000533 76.0
WH2_k127_7238018_5 Iron-binding zinc finger CDGSH type K05710 - - 0.000000001757 61.0
WH2_k127_7238018_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000007266 57.0
WH2_k127_7283139_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 347.0
WH2_k127_7283139_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 289.0
WH2_k127_7283139_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.00000000000000000000000000000000000000000007948 177.0
WH2_k127_7283139_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000008173 123.0
WH2_k127_7283139_4 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000438 73.0
WH2_k127_7283139_5 Prokaryotic N-terminal methylation motif - - - 0.00003211 55.0
WH2_k127_7305757_0 MMPL family K18138 - - 0.0 1205.0
WH2_k127_7305757_1 xanthine dehydrogenase activity K04108 - 1.3.7.9 2.413e-223 706.0
WH2_k127_7305757_2 doubled CXXCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 627.0
WH2_k127_7305757_3 membrane organization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 401.0
WH2_k127_7305757_4 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 329.0
WH2_k127_7305757_5 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 312.0
WH2_k127_7305757_6 Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 330.0
WH2_k127_7305757_7 - - - - 0.000000000000000000000000000000006777 142.0
WH2_k127_7376106_0 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 400.0
WH2_k127_7376106_1 hydrolase activity, acting on ester bonds K07017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 350.0
WH2_k127_7376106_2 amine dehydrogenase activity K17285 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003112 298.0
WH2_k127_7376106_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000005886 194.0
WH2_k127_7436240_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 458.0
WH2_k127_7453849_0 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007038 246.0
WH2_k127_7453849_1 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000001547 185.0
WH2_k127_7453849_2 - - - - 0.000000000000000000000000003473 117.0
WH2_k127_7453849_3 - - - - 0.0000000000000000000000001127 115.0
WH2_k127_7453849_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01476,K01480 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1,3.5.3.11 0.0000000000000004405 79.0
WH2_k127_7503824_0 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 385.0
WH2_k127_7503824_1 Glyoxalase-like domain K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001024 267.0
WH2_k127_7503824_10 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000003605 67.0
WH2_k127_7503824_11 - - - - 0.00000000005728 68.0
WH2_k127_7503824_12 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.000000003546 71.0
WH2_k127_7503824_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000002126 241.0
WH2_k127_7503824_3 nitrous oxide K19341 - - 0.0000000000000000000000000000000000000000000000000000000000001292 231.0
WH2_k127_7503824_4 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000001443 152.0
WH2_k127_7503824_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000006974 149.0
WH2_k127_7503824_6 - - - - 0.0000000000000000000000000000000154 130.0
WH2_k127_7503824_7 enzyme binding K00567,K07443 - 2.1.1.63 0.00000000000000000000000004252 111.0
WH2_k127_7503824_8 Pathogenicity locus - - - 0.0000000000000000000001286 106.0
WH2_k127_7503824_9 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000001018 79.0
WH2_k127_750908_0 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 589.0
WH2_k127_750908_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 381.0
WH2_k127_750908_2 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 339.0
WH2_k127_750908_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000161 286.0
WH2_k127_750908_4 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000005326 196.0
WH2_k127_750908_5 Leishmanolysin - - - 0.000000000003178 79.0
WH2_k127_7545799_0 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000001007 137.0
WH2_k127_7545799_1 heat shock protein binding - - - 0.0000000000000000000001132 107.0
WH2_k127_7546072_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000003577 255.0
WH2_k127_7546072_1 GIY-YIG type nucleases (URI domain) K03703 - - 0.000000000000000000000000000000000000000000000000000000000006371 224.0
WH2_k127_7546072_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000004847 125.0
WH2_k127_7546072_3 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000006848 82.0
WH2_k127_7559039_0 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 539.0
WH2_k127_7559039_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 443.0
WH2_k127_7559039_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 312.0
WH2_k127_7559039_3 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004068 281.0
WH2_k127_7559039_4 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000006256 156.0
WH2_k127_7559039_5 PFAM NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000008337 145.0
WH2_k127_7559039_6 YCII-related domain K09780 - - 0.0000000000000000000000000000001285 125.0
WH2_k127_7559039_7 Belongs to the GcvT family K06980 - - 0.00000000000000000000000005729 114.0
WH2_k127_7559039_8 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.0000000000000000001562 104.0
WH2_k127_7623047_0 CheC-like family K03410 - - 0.00000000000000000000000000000000000000000000000000000000000000001007 230.0
WH2_k127_7623047_1 P2 response regulator binding domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000005626 212.0
WH2_k127_7623047_2 Tetratricopeptide repeat - - - 0.00000000000000002673 85.0
WH2_k127_7662605_0 Carboxyl transferase domain - - - 8.084e-248 775.0
WH2_k127_7662605_1 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 3.674e-194 612.0
WH2_k127_7662605_2 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 400.0
WH2_k127_7662605_3 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 360.0
WH2_k127_7662605_4 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001594 293.0
WH2_k127_7662605_5 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000007716 231.0
WH2_k127_7662605_6 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000002124 223.0
WH2_k127_7662605_7 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000003136 193.0
WH2_k127_7662605_8 PFAM CBS domain containing protein K03699 - - 0.0000000000000000000000000000000000006611 160.0
WH2_k127_7662605_9 translation release factor activity - - - 0.00000000002714 76.0
WH2_k127_7664784_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 302.0
WH2_k127_7664784_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000126 179.0
WH2_k127_7664784_2 Bacterial Ig-like domain - - - 0.000000000000000000000000000000000000000002331 175.0
WH2_k127_7762802_0 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000005583 210.0
WH2_k127_7762802_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000001042 155.0
WH2_k127_7762802_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000001512 147.0
WH2_k127_7762802_3 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000001541 149.0
WH2_k127_7762802_4 Phosphoribosyl transferase domain - - - 0.000003476 55.0
WH2_k127_7770941_0 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 469.0
WH2_k127_7770941_1 Rossmann-like domain - - - 0.00000000000000000000000000003663 128.0
WH2_k127_7770941_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000001497 80.0
WH2_k127_7770941_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000004731 65.0
WH2_k127_7808685_0 Peptidase family M1 domain - - - 1.436e-261 822.0
WH2_k127_7808685_1 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 319.0
WH2_k127_7808685_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 315.0
WH2_k127_7808685_3 - - - - 0.00000000000000000000000000000000000000000000000000000000003843 216.0
WH2_k127_7808685_4 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000000000000000005468 187.0
WH2_k127_7808685_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000001477 138.0
WH2_k127_7821167_0 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 371.0
WH2_k127_7821167_1 COGs COG2409 drug exporter of the RND superfamily K06994 - - 0.000000000000000000000000000000000001577 158.0
WH2_k127_7821167_2 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000007629 127.0
WH2_k127_7821167_3 Alpha beta hydrolase fold K01055 - 3.1.1.24 0.00000000000000000000002393 108.0
WH2_k127_7821167_4 Matrixin - - - 0.0000000000000000000003414 106.0
WH2_k127_7821167_5 Thioesterase K07107,K12500 - - 0.00000000000000000116 94.0
WH2_k127_7821167_6 Lipase maturation factor - - - 0.000000000002235 73.0
WH2_k127_7821167_7 NHL repeat - - - 0.00006439 55.0
WH2_k127_7823802_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 460.0
WH2_k127_7823802_1 Fimbrial assembly protein (PilN) - - - 0.000000000000000000000000000000000002344 147.0
WH2_k127_7823802_2 Pilus assembly protein, PilO K02664 - - 0.00003299 53.0
WH2_k127_7841370_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 394.0
WH2_k127_7841370_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 396.0
WH2_k127_7841370_2 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000003253 231.0
WH2_k127_7841370_3 Outer membrane protein beta-barrel domain - - - 0.000000000000000003103 94.0
WH2_k127_7841370_4 Opacity protein - - - 0.0000000000005231 78.0
WH2_k127_784353_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000002734 195.0
WH2_k127_784353_1 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000009065 148.0
WH2_k127_784353_2 OmpA family K03640 - - 0.00000000000000000000000000000002787 130.0
WH2_k127_7875125_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 345.0
WH2_k127_7875125_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000001324 280.0
WH2_k127_7875125_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.0000000000000000000000000000000000006837 143.0
WH2_k127_7909145_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 477.0
WH2_k127_7909145_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000003402 170.0
WH2_k127_7909145_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000003581 161.0
WH2_k127_7909145_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000004061 139.0
WH2_k127_7909145_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000006183 141.0
WH2_k127_7912474_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 574.0
WH2_k127_7912474_1 Glycosyl hydrolase family 3 N terminal domain K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007245 294.0
WH2_k127_7912474_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000002183 207.0
WH2_k127_7912474_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000004286 63.0
WH2_k127_7912474_4 Forkhead associated domain - - - 0.00000000005461 76.0
WH2_k127_7993164_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 497.0
WH2_k127_7993164_1 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 404.0
WH2_k127_7993164_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 359.0
WH2_k127_7993164_3 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001913 262.0
WH2_k127_7993164_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000006276 108.0
WH2_k127_7993164_5 Lactonase, 7-bladed beta-propeller - - - 0.0003549 54.0
WH2_k127_8012639_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1309.0
WH2_k127_8012639_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000006794 252.0
WH2_k127_8012639_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000001222 224.0
WH2_k127_8012639_3 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000002026 161.0
WH2_k127_8014047_0 RecQ zinc-binding K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001494 285.0
WH2_k127_8014047_1 enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.00000000000000000000000000000000837 132.0
WH2_k127_8017026_0 E1-E2 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 556.0
WH2_k127_8017026_1 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001557 253.0
WH2_k127_8017026_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000008865 235.0
WH2_k127_8017026_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000001139 181.0
WH2_k127_8028938_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.108e-199 638.0
WH2_k127_8028938_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001167 252.0
WH2_k127_8028938_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000001687 129.0
WH2_k127_8062969_0 lysine biosynthetic process via aminoadipic acid - - - 3.015e-236 761.0
WH2_k127_8062969_1 Prokaryotic glutathione synthetase, ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001233 242.0
WH2_k127_8062969_2 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000007523 230.0
WH2_k127_8062969_3 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000345 202.0
WH2_k127_8062969_4 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000245 194.0
WH2_k127_8062969_5 - - - - 0.0000000000000000000000000000000000000009611 160.0
WH2_k127_8062969_6 Putative adhesin - - - 0.0000000000000000000001415 110.0
WH2_k127_8062969_7 Domain of unknown function (DUF4349) - - - 0.0008887 51.0
WH2_k127_8114816_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 574.0
WH2_k127_8114816_1 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 506.0
WH2_k127_8114816_2 - - - - 0.0000000000000000000001489 108.0
WH2_k127_8114816_3 Domain of unknown function (DUF4136) - - - 0.00000000000000000008156 98.0
WH2_k127_8155535_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.193e-289 901.0
WH2_k127_8155535_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.228e-204 652.0
WH2_k127_8155535_10 phosphorelay signal transduction system - - - 0.0000000000000003387 92.0
WH2_k127_8155535_11 BON domain - - - 0.00005674 51.0
WH2_k127_8155535_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 567.0
WH2_k127_8155535_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 525.0
WH2_k127_8155535_4 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 472.0
WH2_k127_8155535_5 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 409.0
WH2_k127_8155535_6 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000002989 207.0
WH2_k127_8155535_7 PFAM BioY protein K03523 - - 0.00000000000000000000000000001753 127.0
WH2_k127_8155535_8 CAAX protease self-immunity K07052 - - 0.000000000000000000000000001054 128.0
WH2_k127_8155535_9 - - - - 0.0000000000000000000000001273 115.0
WH2_k127_816178_0 response regulator K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 415.0
WH2_k127_816178_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000006592 147.0
WH2_k127_8233764_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002142 282.0
WH2_k127_8233764_1 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000001663 203.0
WH2_k127_8233764_2 Cytochrome oxidase maturation protein - - - 0.0000002338 61.0
WH2_k127_8248493_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.357e-197 624.0
WH2_k127_8248493_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 456.0
WH2_k127_8248493_2 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 336.0
WH2_k127_8248493_3 EVE domain - - - 0.00000000000000000000000000000001791 132.0
WH2_k127_8257107_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 428.0
WH2_k127_8257107_1 - - - - 0.000000000000000000000000000000006323 130.0
WH2_k127_8325302_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001525 287.0
WH2_k127_8325302_1 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001352 267.0
WH2_k127_832652_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 436.0
WH2_k127_8344561_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 315.0
WH2_k127_8344561_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000001227 269.0
WH2_k127_8344561_2 bacterial-type flagellum-dependent cell motility - - - 0.000006591 53.0
WH2_k127_8370556_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 490.0
WH2_k127_8370556_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 468.0
WH2_k127_8370556_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 423.0
WH2_k127_8370556_3 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 373.0
WH2_k127_8370556_4 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 345.0
WH2_k127_8370556_5 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000009878 217.0
WH2_k127_8370556_6 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.000000000000000000000000000000000000000000000005555 186.0
WH2_k127_8370556_7 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000531 85.0
WH2_k127_8374533_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 518.0
WH2_k127_8374533_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 429.0
WH2_k127_8374533_2 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 340.0
WH2_k127_8388309_0 Elongator protein 3, MiaB family, Radical SAM K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 530.0
WH2_k127_8388309_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 511.0
WH2_k127_8388309_10 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000001736 98.0
WH2_k127_8388309_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 497.0
WH2_k127_8388309_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 366.0
WH2_k127_8388309_4 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 318.0
WH2_k127_8388309_5 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 312.0
WH2_k127_8388309_6 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003232 284.0
WH2_k127_8388309_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000006514 246.0
WH2_k127_8388309_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000002406 197.0
WH2_k127_8388309_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000116 116.0
WH2_k127_8438304_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 473.0
WH2_k127_8438304_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000007117 261.0
WH2_k127_8438304_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000002649 165.0
WH2_k127_8438304_3 pfkB family carbohydrate kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000003643 118.0
WH2_k127_8438304_4 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000004719 79.0
WH2_k127_846499_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 5.515e-253 806.0
WH2_k127_846499_1 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 580.0
WH2_k127_846499_10 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000005792 149.0
WH2_k127_846499_11 SnoaL-like domain - - - 0.0000000000000000000000000000001725 128.0
WH2_k127_846499_12 - - - - 0.0000000000000003578 88.0
WH2_k127_846499_13 - - - - 0.000000000000009292 86.0
WH2_k127_846499_14 - - - - 0.00000000000213 69.0
WH2_k127_846499_16 - - - - 0.00000006498 63.0
WH2_k127_846499_17 - - - - 0.0001746 48.0
WH2_k127_846499_2 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 341.0
WH2_k127_846499_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 346.0
WH2_k127_846499_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 308.0
WH2_k127_846499_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001188 287.0
WH2_k127_846499_6 protein, Hemolysin III K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002377 271.0
WH2_k127_846499_7 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001387 257.0
WH2_k127_846499_8 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001633 251.0
WH2_k127_846499_9 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000001692 189.0
WH2_k127_8473125_0 Arylsulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 600.0
WH2_k127_8473125_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 477.0
WH2_k127_8473125_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 288.0
WH2_k127_8473125_3 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000000106 152.0
WH2_k127_8497890_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 441.0
WH2_k127_8497890_1 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 401.0
WH2_k127_8497890_2 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 332.0
WH2_k127_8497890_3 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000002122 189.0
WH2_k127_8497890_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000005592 177.0
WH2_k127_8497890_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000001655 122.0
WH2_k127_8497890_6 Protein of unknown function DUF116 K09729 - - 0.0000000000000000002959 99.0
WH2_k127_8499087_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 509.0
WH2_k127_8499087_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009978 274.0
WH2_k127_8499087_2 impB/mucB/samB family K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000002411 188.0
WH2_k127_8499087_3 YhhN family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000007303 158.0
WH2_k127_8499087_4 - - - - 0.000000000000000000000000000002462 128.0
WH2_k127_8499087_5 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0001022 49.0
WH2_k127_8529384_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 358.0
WH2_k127_8529384_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 319.0
WH2_k127_8541297_0 Cupin 2, conserved barrel domain protein K06720 - 4.2.1.108 0.00000000000000000000000000000000000000000000000000000005153 201.0
WH2_k127_8541297_1 peptidase - - - 0.00000000000000000000000000000000000000000004411 168.0
WH2_k127_8541297_2 - - - - 0.00000000000000000000000000000000000000004032 170.0
WH2_k127_8541297_3 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000000001164 132.0
WH2_k127_8561821_0 DNA polymerase alpha chain like domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000018 250.0
WH2_k127_8563831_0 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 391.0
WH2_k127_8563831_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 339.0
WH2_k127_8564710_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 556.0
WH2_k127_8564710_1 tRNA processing K06864 - - 0.0000000000000000000000000000116 122.0
WH2_k127_857405_0 xaa-pro dipeptidase K01271 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009062 442.0
WH2_k127_857405_1 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 401.0
WH2_k127_857405_2 TfoX N-terminal domain - - - 0.00000000002265 64.0
WH2_k127_858145_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 435.0
WH2_k127_858145_1 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000001103 157.0
WH2_k127_858941_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 4.775e-257 801.0
WH2_k127_8609319_0 Peptidase family M3 K08602 - - 6.183e-220 716.0
WH2_k127_8609319_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 460.0
WH2_k127_8609319_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 408.0
WH2_k127_8609319_3 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 344.0
WH2_k127_8609319_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 313.0
WH2_k127_8609319_5 TOBE domain K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000149 286.0
WH2_k127_8609319_6 Cold shock K03704 - - 0.000000000000000000000000000003046 121.0
WH2_k127_8609319_7 serine threonine protein kinase - - - 0.00000000000000000000000000009357 121.0
WH2_k127_8609319_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000005376 107.0
WH2_k127_8635198_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K22110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 312.0
WH2_k127_8635198_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000001638 248.0
WH2_k127_8635198_2 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.00000000000000000000000000000000000000000000000000000001741 203.0
WH2_k127_8635198_3 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000000000000000000000000000002719 201.0
WH2_k127_8635198_4 Permease - - - 0.00000000000000000000000000000000000002734 165.0
WH2_k127_8635198_5 Aldo Keto reductase - - - 0.00000000000000000001361 96.0
WH2_k127_8635198_6 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000004025 89.0
WH2_k127_8635198_7 ATPases associated with a variety of cellular activities K01990 - - 0.0000004909 56.0
WH2_k127_8662651_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 512.0
WH2_k127_8662651_1 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 358.0
WH2_k127_8674898_0 ABC transporter transmembrane region - - - 1.509e-217 712.0
WH2_k127_8674898_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 334.0
WH2_k127_8674898_2 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000008799 140.0
WH2_k127_8674898_3 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.0000000000000000000000000000000003662 150.0
WH2_k127_8699452_0 LVIVD repeat - - - 1.653e-273 867.0
WH2_k127_8699452_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 392.0
WH2_k127_8699452_2 Threonine/Serine exporter, ThrE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 358.0
WH2_k127_8699452_3 - - - - 0.00000000000000000000000000000000113 132.0
WH2_k127_8699452_4 - - - - 0.000000000000000000000000001314 115.0
WH2_k127_8699452_6 SNARE associated Golgi protein - - - 0.0005593 49.0
WH2_k127_8721033_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 358.0
WH2_k127_8721033_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 325.0
WH2_k127_8721033_10 - - - - 0.00000006412 64.0
WH2_k127_8721033_2 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor - - - 0.00000000000000000000000000000000000000000000000000000000000001831 233.0
WH2_k127_8721033_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000001032 194.0
WH2_k127_8721033_4 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000003816 168.0
WH2_k127_8721033_5 - - - - 0.000000000000000000000000000000000002663 146.0
WH2_k127_8721033_6 RESPONSE REGULATOR receiver K02658 - - 0.00000000000000000000000000000438 123.0
WH2_k127_8721033_7 - - - - 0.000000000000000000001557 108.0
WH2_k127_8721033_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000423 102.0
WH2_k127_8721033_9 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000239 89.0
WH2_k127_8774118_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000008557 175.0
WH2_k127_8774118_1 acr, cog1993 K09137 - - 0.000000000000000000000000000000000000000000000128 171.0
WH2_k127_8774118_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000004353 114.0
WH2_k127_8774118_3 Putative phosphatase (DUF442) - - - 0.0000000000000003358 88.0
WH2_k127_878202_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 592.0
WH2_k127_878202_1 acetyltransferase - - - 0.000000000000000000000000000000000000000001036 161.0
WH2_k127_878202_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000003313 89.0
WH2_k127_8814136_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 478.0
WH2_k127_8814136_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 321.0
WH2_k127_8814136_10 - - - - 0.0007487 45.0
WH2_k127_8814136_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000878 270.0
WH2_k127_8814136_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000005371 204.0
WH2_k127_8814136_4 Belongs to the ClpA ClpB family K03695 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009628,GO:0009657,GO:0009658,GO:0009987,GO:0016043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0071840 - 0.0000000000000000000000000000000000000000000000003877 192.0
WH2_k127_8814136_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000293 153.0
WH2_k127_8814136_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000008815 163.0
WH2_k127_8814136_7 Ribosomal protein L33 K02913 - - 0.00000000000000000000007855 97.0
WH2_k127_8814136_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000003689 56.0
WH2_k127_8899318_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 330.0
WH2_k127_8899318_1 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001898 248.0
WH2_k127_8925357_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.444e-227 707.0
WH2_k127_8925357_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 510.0
WH2_k127_8925357_10 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000004956 234.0
WH2_k127_8925357_11 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000003488 244.0
WH2_k127_8925357_12 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000002061 213.0
WH2_k127_8925357_13 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000008535 213.0
WH2_k127_8925357_14 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000001115 187.0
WH2_k127_8925357_15 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000003447 178.0
WH2_k127_8925357_16 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000001812 160.0
WH2_k127_8925357_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000007351 154.0
WH2_k127_8925357_18 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002309 141.0
WH2_k127_8925357_19 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000003927 115.0
WH2_k127_8925357_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 414.0
WH2_k127_8925357_20 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000005767 111.0
WH2_k127_8925357_21 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000002693 117.0
WH2_k127_8925357_22 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000001518 102.0
WH2_k127_8925357_23 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000002755 99.0
WH2_k127_8925357_24 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000008118 97.0
WH2_k127_8925357_25 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000128 76.0
WH2_k127_8925357_26 Ribosomal L29 protein K02904 - - 0.000000000004931 67.0
WH2_k127_8925357_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 398.0
WH2_k127_8925357_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 366.0
WH2_k127_8925357_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 350.0
WH2_k127_8925357_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003295 273.0
WH2_k127_8925357_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000172 253.0
WH2_k127_8925357_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007567 250.0
WH2_k127_8925357_9 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000005579 245.0
WH2_k127_8934834_0 COG0433 Predicted ATPase K06915 - - 7.34e-229 721.0
WH2_k127_8971346_0 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000006942 190.0
WH2_k127_8971346_1 Lytic transglycosylase catalytic - - - 0.00000000000000000000007463 113.0
WH2_k127_8971346_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000937 73.0
WH2_k127_8995622_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.385e-229 721.0
WH2_k127_8995622_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000003587 115.0
WH2_k127_9011822_0 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002935 282.0
WH2_k127_9011822_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002323 262.0
WH2_k127_9011822_2 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000006991 209.0
WH2_k127_9011822_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000003731 205.0
WH2_k127_9011822_4 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000002104 166.0
WH2_k127_9011822_5 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000001952 93.0
WH2_k127_9013770_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 507.0
WH2_k127_9013770_1 E1-E2 ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 318.0
WH2_k127_9013770_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003332 276.0
WH2_k127_9013770_3 of the major facilitator superfamily - - - 0.00000000000000000000000000000000000248 156.0
WH2_k127_9013770_4 negative regulation of transcription, DNA-templated K21600 - - 0.000000000000000000000000000000005398 138.0
WH2_k127_9017878_0 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000414 233.0
WH2_k127_9017878_1 - - - - 0.00000000000006993 79.0
WH2_k127_9023635_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 534.0
WH2_k127_9023635_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 450.0
WH2_k127_9023635_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 394.0
WH2_k127_9023635_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 379.0
WH2_k127_9023635_4 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 300.0
WH2_k127_9023635_5 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000004974 153.0
WH2_k127_9023635_6 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000003002 111.0
WH2_k127_9028310_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000406 226.0
WH2_k127_9028310_1 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000002724 181.0
WH2_k127_9035782_0 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 309.0
WH2_k127_9035782_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 292.0
WH2_k127_9084341_0 Domain of unknown function DUF87 K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 531.0
WH2_k127_9084341_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000002116 243.0
WH2_k127_910814_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.262e-270 856.0
WH2_k127_910814_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 401.0
WH2_k127_910814_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000002581 209.0
WH2_k127_910814_3 Melibiase K07407 GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0009056,GO:0015925,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0042802,GO:0042803,GO:0046983,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 3.2.1.22 0.0000000000002885 77.0
WH2_k127_910814_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000001106 66.0
WH2_k127_9182109_0 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 385.0
WH2_k127_9182109_1 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000001042 251.0
WH2_k127_9182109_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000002288 243.0
WH2_k127_9182109_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001739 253.0
WH2_k127_9182109_4 creatininase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000000000003861 206.0
WH2_k127_9182109_5 - - - - 0.000000002708 69.0
WH2_k127_9188859_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 586.0
WH2_k127_9188859_1 Zinc dependent phospholipase C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 325.0
WH2_k127_9188859_2 long-chain fatty acid transport protein - - - 0.000000000000004429 81.0
WH2_k127_9236757_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.082e-237 754.0
WH2_k127_9236757_1 peptidase S9 prolyl oligopeptidase active site K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 521.0
WH2_k127_9236757_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 412.0
WH2_k127_9236757_3 Competence-damaged protein K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 362.0
WH2_k127_9236757_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004926 273.0
WH2_k127_9236757_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000005361 135.0
WH2_k127_9236757_6 PFAM membrane protein of K08972 - - 0.00000000000000000000000000005965 120.0
WH2_k127_9243634_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 358.0
WH2_k127_9243634_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 348.0
WH2_k127_9244747_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 424.0
WH2_k127_9244747_1 Erythromycin esterase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000001329 249.0
WH2_k127_9244747_10 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000004189 86.0
WH2_k127_9244747_2 Dienelactone hydrolase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000003363 242.0
WH2_k127_9244747_3 HAD-hyrolase-like K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
WH2_k127_9244747_4 ABC1 family K03688 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000002075 219.0
WH2_k127_9244747_5 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000007498 180.0
WH2_k127_9244747_6 'Molybdopterin - - - 0.0000000000000000000000000000000000000001766 169.0
WH2_k127_9244747_7 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000001861 147.0
WH2_k127_9244747_8 DNA restriction-modification system - - - 0.00000000000000000000000005665 117.0
WH2_k127_9274533_0 TrkA-C domain K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 616.0
WH2_k127_9274533_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K00567,K01247 - 2.1.1.63,3.2.2.21 0.000000000000000000000000000000000000000001318 158.0
WH2_k127_9274533_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000002218 98.0
WH2_k127_9301226_0 esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000005739 242.0
WH2_k127_9301226_1 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000005482 216.0
WH2_k127_9306637_0 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 579.0
WH2_k127_9306637_1 Domain of unknown function (DUF4403) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006642 269.0
WH2_k127_9306637_2 protein conserved in bacteria K21470 - - 0.000000000000003391 85.0
WH2_k127_9322725_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 580.0
WH2_k127_9322725_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001409 248.0
WH2_k127_9322725_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000574 117.0
WH2_k127_9323009_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 472.0
WH2_k127_9323009_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 431.0
WH2_k127_9323009_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 446.0
WH2_k127_9323009_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 427.0
WH2_k127_9323009_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 409.0
WH2_k127_9323009_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 394.0
WH2_k127_9323009_6 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 322.0
WH2_k127_9323009_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 319.0
WH2_k127_9323009_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000082 288.0
WH2_k127_9365305_0 - - - - 0.0000000004191 71.0
WH2_k127_9365305_1 SnoaL-like domain - - - 0.0000003719 61.0
WH2_k127_937348_0 High confidence in function and specificity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 568.0
WH2_k127_937348_1 PFAM Integrase, catalytic core - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 546.0
WH2_k127_937348_2 SMART AAA ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 334.0
WH2_k127_937348_3 - - - - 0.00000000000000000000000000000000000917 144.0
WH2_k127_9390506_0 PA14 domain K05349 - 3.2.1.21 5.874e-265 832.0
WH2_k127_9390506_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000004873 107.0
WH2_k127_9414489_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 341.0
WH2_k127_9414489_1 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000009012 149.0
WH2_k127_9414489_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000003506 149.0
WH2_k127_9443941_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 425.0
WH2_k127_9443941_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 318.0
WH2_k127_9443941_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000002247 280.0
WH2_k127_9471283_0 Histidine kinase - - - 1.919e-200 645.0
WH2_k127_9471283_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 338.0
WH2_k127_9471283_2 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007465 301.0
WH2_k127_9471283_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000005956 238.0
WH2_k127_9471283_4 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.0009222 42.0
WH2_k127_947260_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 3.056e-228 719.0
WH2_k127_947260_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000005974 188.0
WH2_k127_9496483_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002322 269.0
WH2_k127_9496483_1 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000002845 193.0
WH2_k127_9496483_2 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000001867 98.0
WH2_k127_952093_0 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003547 272.0
WH2_k127_952093_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000002836 186.0
WH2_k127_952093_2 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000005597 172.0
WH2_k127_952093_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000001095 139.0
WH2_k127_9521357_0 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000005043 243.0
WH2_k127_9521357_1 deoxyhypusine monooxygenase activity - - - 0.00000189 61.0
WH2_k127_9739514_0 DNA-directed DNA polymerase K02337,K14162 - 2.7.7.7 7.296e-224 724.0
WH2_k127_9739514_1 Mechanosensitive ion channel K05802 - - 0.00000005129 64.0
WH2_k127_9755297_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 527.0
WH2_k127_9755297_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 510.0
WH2_k127_9755297_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 492.0
WH2_k127_9755297_3 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 486.0
WH2_k127_9755297_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002742 257.0
WH2_k127_9755297_5 Phosphoribosyl transferase domain - - - 0.00000000000000000000000001804 113.0
WH2_k127_9755297_6 Preprotein translocase SecG subunit K03075 - - 0.0000000000000001156 85.0
WH2_k127_9755830_0 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 546.0
WH2_k127_9755830_1 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000003034 219.0
WH2_k127_9755830_2 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000005557 152.0
WH2_k127_9755830_3 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000758 132.0
WH2_k127_9755830_4 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000003878 130.0
WH2_k127_9755830_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000003798 100.0
WH2_k127_9759193_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 624.0
WH2_k127_9759193_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 560.0
WH2_k127_9759193_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000004517 222.0
WH2_k127_9759193_3 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000002657 187.0
WH2_k127_9759193_4 Participates in the control of copper homeostasis K06201 - - 0.00000000000000000000000000000000000000000000002081 180.0
WH2_k127_9759193_5 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000001646 121.0
WH2_k127_9759193_6 Peptidase family M23 - - - 0.000005708 55.0
WH2_k127_9782240_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 430.0
WH2_k127_9782240_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 377.0
WH2_k127_9782240_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000003725 171.0
WH2_k127_9786741_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 415.0
WH2_k127_9786741_1 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000009559 82.0
WH2_k127_9786741_2 Endoribonuclease L-PSP - - - 0.0000000002291 71.0
WH2_k127_9786741_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00005332 52.0
WH2_k127_9809621_0 Uncharacterized protein family (UPF0051) K09014 - - 3.034e-254 796.0
WH2_k127_9809621_1 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 325.0
WH2_k127_9809621_2 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001774 268.0
WH2_k127_9809621_3 Ndr family - - - 0.000000000000000000000000000000000000000000004897 170.0
WH2_k127_9809621_4 HTH domain - - - 0.00000000000000000000000000000000000000000008813 169.0
WH2_k127_9809621_5 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000001965 161.0
WH2_k127_9809621_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000001305 142.0
WH2_k127_9823924_0 protein kinase activity - - - 8.495e-213 690.0
WH2_k127_9823924_1 protein kinase activity - - - 4.669e-203 662.0
WH2_k127_9823924_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 623.0
WH2_k127_9823924_3 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 602.0
WH2_k127_9823924_4 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 559.0
WH2_k127_9823924_5 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 333.0
WH2_k127_9823924_6 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000001306 264.0
WH2_k127_9844746_0 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 428.0
WH2_k127_9844746_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001699 255.0
WH2_k127_9844746_2 heat shock protein binding - - - 0.0000000000000000000000000000001884 132.0
WH2_k127_9857094_0 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005626 272.0
WH2_k127_9857094_1 pilus organization K07004 - - 0.0000000000000000000000000000000000000000000000004209 191.0
WH2_k127_9857094_2 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 0.0000000000000000000000001209 113.0
WH2_k127_9896527_0 ABC transporter transmembrane region K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 306.0
WH2_k127_9896527_1 - - - - 0.000000000000000001305 95.0
WH2_k127_9926623_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 564.0
WH2_k127_9926623_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 518.0
WH2_k127_9926623_2 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000002341 86.0
WH2_k127_9926623_3 Protein of unknown function (DUF2892) - - - 0.0000000004712 67.0
WH2_k127_9945737_0 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000001233 199.0
WH2_k127_9945737_1 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000001814 92.0
WH2_k127_9945737_2 LysM domain - - - 0.0000000000000003562 91.0
WH2_k127_9985961_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 614.0
WH2_k127_9985961_1 PAS domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 387.0
WH2_k127_9985961_2 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000225 165.0
WH2_k127_9985961_3 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000001554 120.0
WH2_k127_9985961_4 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000007398 104.0
WH2_k127_9985961_5 Histidine kinase - - - 0.000000000007606 72.0
WH2_k127_999654_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001856 287.0
WH2_k127_999654_2 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000002851 122.0
WH2_k127_999654_3 peptidyl-tyrosine sulfation - - - 0.000000007473 65.0