Overview

ID MAG04118
Name WH2_bin.28
Sample SMP0107
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Desulfobacteria
Order Desulfobacterales
Family Desulfosalsimonadaceae
Genus SURF-3
Species SURF-3 sp003599885
Assembly information
Completeness (%) 82.82
Contamination (%) 1.17
GC content (%) 50.0
N50 (bp) 4,039
Genome size (bp) 2,638,355

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2686

Gene name Description KEGG GOs EC E-value Score Sequence
WH2_k127_10038612_0 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 403.0
WH2_k127_10038612_1 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 353.0
WH2_k127_10038612_2 cyclic nucleotide binding K04739,K10914 - - 0.000000000000000000000000000000000000009791 151.0
WH2_k127_10046803_0 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 464.0
WH2_k127_10046803_1 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 331.0
WH2_k127_10046803_2 PFAM Cytochrome c, bacterial - - - 0.0000000000000000000000000000000002541 132.0
WH2_k127_100524_0 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 591.0
WH2_k127_100524_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 287.0
WH2_k127_100524_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003817 277.0
WH2_k127_100524_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000006763 258.0
WH2_k127_100524_4 TIGRFAM maf protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000001267 219.0
WH2_k127_100524_5 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000007358 168.0
WH2_k127_10059895_0 PFAM Acetyl-CoA hydrolase transferase - - - 1.586e-297 923.0
WH2_k127_10059895_1 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 506.0
WH2_k127_10059895_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 499.0
WH2_k127_10059895_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 450.0
WH2_k127_10059895_4 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 436.0
WH2_k127_10059895_5 Universal stress protein family - - - 0.00000000000000000000000000000000000007595 146.0
WH2_k127_10105666_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 546.0
WH2_k127_10105666_1 Single cache domain 3 K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001474 237.0
WH2_k127_10105666_2 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000001864 172.0
WH2_k127_10119823_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 624.0
WH2_k127_10119823_1 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 306.0
WH2_k127_10119823_2 Belongs to the bacterial histone-like protein family K05788 - - 0.00000000000000000000000000000000000000001073 155.0
WH2_k127_10119823_3 PFAM PSP1 domain protein - - - 0.000000000000168 71.0
WH2_k127_10131782_0 PFAM Hydantoinase oxoprolinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 299.0
WH2_k127_10131782_1 PFAM CMP dCMP deaminase zinc-binding K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000007233 203.0
WH2_k127_10131782_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0070566,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.0000000000000000232 87.0
WH2_k127_10142456_0 nitric oxide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 512.0
WH2_k127_10142456_1 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000472 215.0
WH2_k127_10142456_2 PFAM HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000004463 200.0
WH2_k127_10142456_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K05337 - - 0.000000000000000000000000005962 110.0
WH2_k127_10174304_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.767e-196 621.0
WH2_k127_10174304_1 Transglycosylase SLT domain K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 310.0
WH2_k127_10174304_2 TIGRFAM histidinol phosphate phosphatase HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 292.0
WH2_k127_10174304_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000001034 216.0
WH2_k127_10174304_4 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000001264 78.0
WH2_k127_10196016_0 PFAM malic K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 344.0
WH2_k127_10196016_1 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000006805 207.0
WH2_k127_10196016_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000003402 96.0
WH2_k127_10196016_3 Domain of unknown function (DUF4398) - - - 0.00000000000277 72.0
WH2_k127_10200546_0 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 314.0
WH2_k127_10200546_1 Pseudouridine synthase K06175 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 285.0
WH2_k127_10200546_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000007304 223.0
WH2_k127_10200546_3 TIGRFAM phosphonopyruvate decarboxylase-related protein K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000001272 217.0
WH2_k127_10200546_4 Protein conserved in bacteria K09954 - - 0.0000000000000000000000000005395 114.0
WH2_k127_10208407_0 PFAM Alpha amylase K00700 - 2.4.1.18 7.749e-292 907.0
WH2_k127_10208407_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000334 252.0
WH2_k127_10235303_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 574.0
WH2_k127_10235303_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 300.0
WH2_k127_10235303_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000006758 93.0
WH2_k127_10245676_0 COG0451 Nucleoside-diphosphate-sugar K01784 - 5.1.3.2 0.000000000000000000000000000000000000003032 166.0
WH2_k127_10245676_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000008582 148.0
WH2_k127_10245676_2 PFAM nickel-dependent hydrogenase, large subunit K00436 - 1.12.1.2 0.0000000000000000000000000007984 113.0
WH2_k127_10248271_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 8.125e-199 627.0
WH2_k127_10248271_1 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 576.0
WH2_k127_10248271_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 447.0
WH2_k127_10248271_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 394.0
WH2_k127_10248271_4 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 370.0
WH2_k127_10248271_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000538 258.0
WH2_k127_10248271_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004948 252.0
WH2_k127_10248271_7 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) K05967 - - 0.000000000000000000000000000000000000000000000000000000005684 204.0
WH2_k127_10248271_8 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000346 168.0
WH2_k127_10258371_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 406.0
WH2_k127_10258371_1 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 358.0
WH2_k127_10258371_2 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 321.0
WH2_k127_10258371_3 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000000000000000000000000000513 204.0
WH2_k127_10258371_4 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000366 156.0
WH2_k127_10258371_5 Two component signalling adaptor domain K03408 - - 0.0000000000000000002145 94.0
WH2_k127_10262618_0 Proton-conducting membrane transporter K12137 - - 5.819e-214 677.0
WH2_k127_10262618_1 cysteinyl-tRNA synthetase K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000005216 174.0
WH2_k127_10262618_2 - - - - 0.00000000000009037 82.0
WH2_k127_1027576_0 General secretory system II protein E domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 610.0
WH2_k127_10322182_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 420.0
WH2_k127_10322182_1 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001204 280.0
WH2_k127_10322182_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002683 250.0
WH2_k127_10322182_3 DDE superfamily endonuclease K07494 - - 0.0000000000000005903 78.0
WH2_k127_10341963_0 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 497.0
WH2_k127_10341963_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 420.0
WH2_k127_10341963_2 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000005919 153.0
WH2_k127_1034803_0 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 433.0
WH2_k127_1034803_1 Phage integrase family - - - 0.00000000000000002599 83.0
WH2_k127_10353258_0 ABC transporter transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 471.0
WH2_k127_10353258_1 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 455.0
WH2_k127_10353258_2 PFAM ribonuclease II K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000001048 145.0
WH2_k127_10377219_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.124e-299 929.0
WH2_k127_10377219_1 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000001004 143.0
WH2_k127_10433657_0 Dynamin family - - - 3.647e-209 674.0
WH2_k127_10433657_1 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 301.0
WH2_k127_10433657_2 HemY protein - - - 0.000000000000000000000000000000000000000000000001181 181.0
WH2_k127_10433657_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000003012 166.0
WH2_k127_10433657_4 - - - - 0.0000000000000001211 81.0
WH2_k127_10456647_0 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 430.0
WH2_k127_10456647_1 Transcriptional regulator K03603,K04043,K05799 - - 0.0000000000000000000000003442 113.0
WH2_k127_1046536_0 Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 572.0
WH2_k127_1046536_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009062 499.0
WH2_k127_1046536_2 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 453.0
WH2_k127_1046536_3 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004531 274.0
WH2_k127_1046536_4 WHG domain - - - 0.0000000000000000000000000000026 126.0
WH2_k127_10479606_0 UvrD/REP helicase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 605.0
WH2_k127_10479606_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 542.0
WH2_k127_10479606_2 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 294.0
WH2_k127_10479606_3 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001924 269.0
WH2_k127_10479606_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000003507 181.0
WH2_k127_10479606_5 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000003346 121.0
WH2_k127_10479606_6 - - - - 0.0000000000000000001107 95.0
WH2_k127_10479606_7 lyase activity - - - 0.000005314 59.0
WH2_k127_1048047_0 PFAM GAF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000006114 231.0
WH2_k127_1048047_1 CGGC - - - 0.00000000000000000000000000000000000000000000000000000000001797 208.0
WH2_k127_1048047_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000001044 113.0
WH2_k127_1048047_3 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000003011 114.0
WH2_k127_1048047_4 Multidrug transporter - - - 0.000000000864 64.0
WH2_k127_10496124_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 557.0
WH2_k127_10496124_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 341.0
WH2_k127_10496124_2 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 318.0
WH2_k127_10496124_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000001142 186.0
WH2_k127_10496124_4 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000004949 166.0
WH2_k127_10496124_5 Universal stress protein family - - - 0.00000000000000000001388 102.0
WH2_k127_10496124_6 - - - - 0.0000000000000959 74.0
WH2_k127_1051045_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.534e-202 637.0
WH2_k127_1051045_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 9.036e-195 615.0
WH2_k127_1051045_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 402.0
WH2_k127_1051045_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 371.0
WH2_k127_1051045_4 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 366.0
WH2_k127_1051045_5 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000007133 271.0
WH2_k127_1051045_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000074 258.0
WH2_k127_1051045_7 Essential cell division protein K03589 - - 0.00000000000000000000000000000000000000001323 164.0
WH2_k127_10523517_0 MFS/sugar transport protein K03292 - - 6.242e-198 626.0
WH2_k127_10523517_1 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 309.0
WH2_k127_10523517_2 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000000000003807 204.0
WH2_k127_10524677_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 565.0
WH2_k127_10524677_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000004826 192.0
WH2_k127_10524677_2 aconitate hydratase K01681 - 4.2.1.3 0.0000000000000000533 83.0
WH2_k127_1052970_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 385.0
WH2_k127_1052970_1 PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003418 231.0
WH2_k127_1052970_2 PFAM Radical SAM domain protein - - - 0.0000004986 51.0
WH2_k127_10542608_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 348.0
WH2_k127_10542608_1 - K20326 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 305.0
WH2_k127_10542608_2 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 298.0
WH2_k127_10542608_3 - - - - 0.000000000000000000000000000000000000000000000000000000000003813 219.0
WH2_k127_10568950_0 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 503.0
WH2_k127_10568950_1 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 347.0
WH2_k127_10568950_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 316.0
WH2_k127_10568950_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 297.0
WH2_k127_10568950_4 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000000000000000000000000000008244 161.0
WH2_k127_10628027_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 2.892e-265 837.0
WH2_k127_10628027_1 peptidyl-tyrosine sulfation - - - 0.0000000000000001463 86.0
WH2_k127_10638741_0 Psort location Cytoplasmic, score K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 586.0
WH2_k127_10638741_1 - - - - 0.0000000000000000000000000000000000000000000000000000001628 206.0
WH2_k127_10640948_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 386.0
WH2_k127_10640948_1 Anion-transporting ATPase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 290.0
WH2_k127_10640948_2 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001098 270.0
WH2_k127_10640948_3 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009518 248.0
WH2_k127_10640948_4 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000002765 97.0
WH2_k127_10661201_0 Macrocin-O-methyltransferase (TylF) K05303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009536 263.0
WH2_k127_10661201_1 Sulfotransferase family - - - 0.000000000000000000000000000000000000003128 155.0
WH2_k127_10661201_2 amine dehydrogenase activity K01219 - 3.2.1.81 0.000000000001219 81.0
WH2_k127_10661201_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000006821 64.0
WH2_k127_10664926_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 1.779e-198 624.0
WH2_k127_10664926_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 423.0
WH2_k127_10664926_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000005888 232.0
WH2_k127_10664926_3 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000000000000000000005782 147.0
WH2_k127_1066688_0 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 303.0
WH2_k127_1066688_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002562 225.0
WH2_k127_1066688_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000002 113.0
WH2_k127_10667597_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 591.0
WH2_k127_10667597_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 329.0
WH2_k127_10667597_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000001057 156.0
WH2_k127_10667597_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000006902 143.0
WH2_k127_1068769_0 amino acid carrier protein K03310 - - 3.268e-225 704.0
WH2_k127_10713941_0 FAD dependent oxidoreductase K00111 - 1.1.5.3 1.785e-195 623.0
WH2_k127_10713941_1 Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit K00112 - 1.1.5.3 0.000000000000000000000000000000000000000000000005886 176.0
WH2_k127_10778218_0 Bacterial conjugation TrbI-like protein K20533 - - 6.962e-257 794.0
WH2_k127_10778218_1 TrbL/VirB6 plasmid conjugal transfer protein K07344 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 568.0
WH2_k127_10778218_2 Conjugal transfer protein K20532 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 562.0
WH2_k127_10778218_3 VirB8 protein K20531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 449.0
WH2_k127_10778218_4 Conjugal transfer protein TrbH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002687 277.0
WH2_k127_1089920_0 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000002237 163.0
WH2_k127_1089920_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline - - - 0.0000000000000000000000000002589 117.0
WH2_k127_1098866_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.864e-295 914.0
WH2_k127_1120384_0 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 377.0
WH2_k127_1120384_1 VWA containing CoxE family protein K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 312.0
WH2_k127_1120384_2 SH3 domain - - - 0.0000000000000000000000000000000000000002203 154.0
WH2_k127_1120384_3 Tetratricopeptide repeat-like domain - - - 0.000000000005334 71.0
WH2_k127_1173614_0 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000002407 219.0
WH2_k127_1173614_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001419 183.0
WH2_k127_1173614_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000007241 161.0
WH2_k127_1182450_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 570.0
WH2_k127_1182450_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 501.0
WH2_k127_1182450_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 469.0
WH2_k127_1182450_3 Protein of unknown function (DUF933) K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 442.0
WH2_k127_1182450_4 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 342.0
WH2_k127_1182450_5 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000004128 235.0
WH2_k127_1182450_6 transcriptional regulator, AsnC family - - - 0.00000000000000000000000000000000000000000000000000000000000009019 216.0
WH2_k127_1182450_7 DoxX - - - 0.00000000000000000000000000000000008258 139.0
WH2_k127_1182450_8 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000001154 138.0
WH2_k127_1182450_9 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000009595 64.0
WH2_k127_1192043_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.11e-207 650.0
WH2_k127_1192043_1 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 388.0
WH2_k127_1192043_2 UV-endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 391.0
WH2_k127_1192043_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000008029 224.0
WH2_k127_1192043_4 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 0.00000000000000000000000000000000000000000000000000000001848 199.0
WH2_k127_1192043_5 E3 Ubiquitin ligase - - - 0.000000000000000000000000000000000000000000000001218 196.0
WH2_k127_1192043_6 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000006062 177.0
WH2_k127_1192043_7 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000003511 122.0
WH2_k127_1205455_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 1.299e-194 614.0
WH2_k127_1205455_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 465.0
WH2_k127_1205455_2 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000007258 263.0
WH2_k127_1205455_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000001619 259.0
WH2_k127_1205455_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000005824 89.0
WH2_k127_1205455_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000002005 63.0
WH2_k127_1225384_0 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 482.0
WH2_k127_1225384_1 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 429.0
WH2_k127_1225384_2 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000002046 154.0
WH2_k127_1225384_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000006867 115.0
WH2_k127_1225384_4 PilZ domain - - - 0.0000007169 56.0
WH2_k127_1249051_0 Sulfate permease family K03321 - - 2.254e-212 672.0
WH2_k127_1249051_1 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000004128 195.0
WH2_k127_1261992_0 GMC oxidoreductase K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 504.0
WH2_k127_1261992_1 - - - - 0.00000000000000000000000000000000000000000008929 167.0
WH2_k127_1261992_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000898 51.0
WH2_k127_1270411_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 4.155e-214 680.0
WH2_k127_1270411_1 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000009047 220.0
WH2_k127_1272618_0 AMP-binding enzyme C-terminal domain K00666,K20034 - 6.2.1.44 2.143e-263 820.0
WH2_k127_1272618_1 sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 524.0
WH2_k127_1272618_2 7TM diverse intracellular signalling - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 481.0
WH2_k127_1272618_3 Belongs to the peptidase S11 family K01286,K07258,K07262 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005061 284.0
WH2_k127_1272618_4 domain-containing protein K16726 GO:0000785,GO:0001568,GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0001817,GO:0001819,GO:0001944,GO:0001955,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002831,GO:0002833,GO:0003674,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0006275,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007346,GO:0007399,GO:0007423,GO:0007492,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010506,GO:0010507,GO:0010556,GO:0010564,GO:0010639,GO:0010646,GO:0010647,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0012505,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031329,GO:0031330,GO:0031347,GO:0031349,GO:0031430,GO:0031672,GO:0031674,GO:0031965,GO:0031967,GO:0031975,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0039531,GO:0039533,GO:0039535,GO:0040011,GO:0042692,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043122,GO:0043123,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043900,GO:0043902,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045214,GO:0045595,GO:0045596,GO:0045787,GO:0045931,GO:0046530,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050688,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051147,GO:0051148,GO:0051150,GO:0051151,GO:0051171,GO:0051239,GO:0051240,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055001,GO:0055002,GO:0060255,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071695,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090068,GO:0090596,GO:0097435,GO:0098542,GO:0099080,GO:0099081,GO:0099512,GO:1900087,GO:1900245,GO:1900246,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902531,GO:1902533,GO:1902806,GO:1902808,GO:1903146,GO:1903147,GO:2000045,GO:2000112 - 0.00000000000000000000000000001184 134.0
WH2_k127_1272618_5 PFAM Type IV pilus assembly PilZ - - - 0.0000000299 60.0
WH2_k127_1272618_6 Super-infection exclusion protein B - - - 0.000002965 58.0
WH2_k127_1300770_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1510.0
WH2_k127_1320022_0 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 1.937e-195 617.0
WH2_k127_1320022_1 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 319.0
WH2_k127_1320022_2 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001067 261.0
WH2_k127_1320022_3 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0000000000000000000000000000000000000000000009989 167.0
WH2_k127_1320022_4 - - - - 0.000000000000000000000000000005693 128.0
WH2_k127_1320022_5 Methylase involved in ubiquinone menaquinone biosynthesis K03183 - 2.1.1.163,2.1.1.201 0.0000000006944 63.0
WH2_k127_1324970_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 585.0
WH2_k127_1324970_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000008379 168.0
WH2_k127_1329539_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 503.0
WH2_k127_1329539_1 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 401.0
WH2_k127_1329539_2 Methylase involved in ubiquinone menaquinone biosynthesis K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000007883 179.0
WH2_k127_1329539_3 - - - - 0.000000000000003238 83.0
WH2_k127_1342791_0 acyl-CoA dehydrogenase K09456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 591.0
WH2_k127_1342791_1 pfam abc-1 K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 539.0
WH2_k127_1351615_0 Voltage gated chloride channel K03281 - - 6.27e-226 711.0
WH2_k127_1351615_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 366.0
WH2_k127_1351615_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 357.0
WH2_k127_1351615_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004496 259.0
WH2_k127_1351615_4 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000009825 177.0
WH2_k127_1351615_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000004646 142.0
WH2_k127_1369054_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1323.0
WH2_k127_1369054_1 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 492.0
WH2_k127_1369054_2 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 386.0
WH2_k127_1386002_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 1.74e-198 627.0
WH2_k127_1386002_1 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 351.0
WH2_k127_1386002_2 PFAM phosphotransferase KptA Tpt1 K07559 - - 0.00000000000000000000000000001398 123.0
WH2_k127_1386152_0 Transposase (IS116 IS110 IS902 family) - - - 1.467e-261 817.0
WH2_k127_1386152_1 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 377.0
WH2_k127_1393192_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 454.0
WH2_k127_1393192_1 SMART metal-dependent phosphohydrolase HD region K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 316.0
WH2_k127_1393192_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000001808 229.0
WH2_k127_1393192_3 - - - - 0.00000000000000000000006271 108.0
WH2_k127_140282_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 1.052e-202 651.0
WH2_k127_140282_1 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 523.0
WH2_k127_140282_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 427.0
WH2_k127_140282_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000001403 222.0
WH2_k127_140282_4 - - - - 0.000000000000000000000000001316 114.0
WH2_k127_1426462_0 AcrB/AcrD/AcrF family K03296 - - 2.281e-222 698.0
WH2_k127_1426462_1 PFAM Outer membrane efflux protein - - - 7.542e-202 641.0
WH2_k127_1426462_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 458.0
WH2_k127_1426462_3 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000001182 261.0
WH2_k127_1454793_0 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 1.613e-212 666.0
WH2_k127_1454793_1 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 467.0
WH2_k127_1454793_2 - - - - 0.0000000000182 64.0
WH2_k127_1454793_3 Cytochrome c7 and related cytochrome c - - - 0.000000004458 62.0
WH2_k127_1476133_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 428.0
WH2_k127_1476133_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006401 281.0
WH2_k127_1476133_2 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000000000000000000000000000000000000000000008958 244.0
WH2_k127_1476133_3 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000485 226.0
WH2_k127_1476133_4 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000003799 222.0
WH2_k127_1478482_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 467.0
WH2_k127_1478482_1 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 426.0
WH2_k127_1478482_2 nitric oxide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 361.0
WH2_k127_1478482_4 Belongs to the ArsC family - - - 0.000000000000000000003029 96.0
WH2_k127_149576_0 PFAM Starch synthase catalytic K00703,K01176 - 2.4.1.21,3.2.1.1 3.625e-215 679.0
WH2_k127_149576_1 phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000002683 193.0
WH2_k127_1502484_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 9.273e-279 866.0
WH2_k127_1502484_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000007782 193.0
WH2_k127_1502484_2 - - - - 0.0000000005694 61.0
WH2_k127_1509239_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 467.0
WH2_k127_1509239_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 425.0
WH2_k127_1509239_2 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000007866 138.0
WH2_k127_1520138_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 443.0
WH2_k127_1520138_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007148 267.0
WH2_k127_1520138_2 PFAM DoxX family protein - - - 0.0000000000000000000000000000000000000000006797 163.0
WH2_k127_1520138_3 to SP P29212 GB L02649 GB X70994 PID 581070 GB U00096 percent identity K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000037 129.0
WH2_k127_1520138_4 Redoxin domain protein - - - 0.00000000000000000000000000003141 124.0
WH2_k127_1520138_5 - - - - 0.00000000000000000004418 95.0
WH2_k127_1520138_6 integral membrane protein - - - 0.0000000000000004129 87.0
WH2_k127_1520138_7 Protein of unknown function (DUF2752) - - - 0.0002575 49.0
WH2_k127_1520701_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 404.0
WH2_k127_1520701_1 PFAM ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 378.0
WH2_k127_1520701_2 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 322.0
WH2_k127_1520701_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000134 243.0
WH2_k127_1520701_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000001916 237.0
WH2_k127_15218_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003823 267.0
WH2_k127_15218_1 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000004931 215.0
WH2_k127_15218_2 fatty acid responsive transcription factor FadR domain protein K03603 - - 0.000000000000000000000000000000000000000000000000000000000003959 216.0
WH2_k127_15218_3 Macrophage migration inhibitory factor (MIF) - - - 0.00000000000000000000000001675 113.0
WH2_k127_15218_4 Alpha/beta hydrolase family - - - 0.0002309 48.0
WH2_k127_1535508_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 357.0
WH2_k127_1538059_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000003618 171.0
WH2_k127_1538059_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000015 165.0
WH2_k127_1538059_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000007227 152.0
WH2_k127_1538059_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000477 95.0
WH2_k127_1538059_4 Uncharacterized ACR, COG1993 - - - 0.000307 45.0
WH2_k127_155069_0 Protein tyrosine serine phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000523 173.0
WH2_k127_155069_1 Copper binding proteins, plastocyanin azurin family - - - 0.0004386 50.0
WH2_k127_1600163_0 oxidoreductase activity - - - 3.981e-241 764.0
WH2_k127_1600163_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.596e-223 704.0
WH2_k127_1600163_2 4Fe-4S single cluster domain K05337 - - 0.000000000000000004971 87.0
WH2_k127_1600163_3 VirC1 protein K03496 - - 0.00000000212 67.0
WH2_k127_1600163_4 Metallo-beta-lactamase superfamily - - - 0.00000002945 55.0
WH2_k127_1607395_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.366e-309 962.0
WH2_k127_1612030_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 4.639e-267 830.0
WH2_k127_1612030_1 FAD dependent oxidoreductase K16885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 366.0
WH2_k127_1656780_0 Neutral/alkaline non-lysosomal ceramidase, C-terminal K12349 - 3.5.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 462.0
WH2_k127_1656780_1 - K09986 - - 0.0000000000000000000000000000000000000000001084 165.0
WH2_k127_1656780_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000005519 71.0
WH2_k127_1656780_3 Protein of unknown function (DUF1499) - - - 0.000002895 52.0
WH2_k127_1656780_4 CAAX amino terminal protease family - - - 0.00007551 55.0
WH2_k127_1668664_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 358.0
WH2_k127_1668664_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000003217 198.0
WH2_k127_1672292_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 4.081e-195 639.0
WH2_k127_1672292_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 571.0
WH2_k127_1672292_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 309.0
WH2_k127_1672292_3 Protein of unknown function (DUF1499) - - - 0.00000000008473 64.0
WH2_k127_1674260_0 PFAM oxidoreductase domain protein K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 381.0
WH2_k127_1674260_1 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 344.0
WH2_k127_1674260_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000001259 160.0
WH2_k127_1674260_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0008731 44.0
WH2_k127_1678530_0 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 447.0
WH2_k127_1710401_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 530.0
WH2_k127_1710401_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 385.0
WH2_k127_1710401_2 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 355.0
WH2_k127_1711394_0 CheY-like receiver, AAA-type ATPase and DNA-binding domain-containing response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001485 261.0
WH2_k127_1711394_1 - - - - 0.0000000000000000000153 93.0
WH2_k127_1733079_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.148e-212 669.0
WH2_k127_1746956_0 PFAM DAHP synthetase I K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 483.0
WH2_k127_1746956_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000002222 90.0
WH2_k127_1746956_2 Phosphofructokinase K00895,K21071 - 2.7.1.11,2.7.1.90 0.00003284 48.0
WH2_k127_1760753_0 acyl-coa dehydrogenase K09456 - - 4.998e-240 751.0
WH2_k127_1803019_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 528.0
WH2_k127_1803019_1 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 288.0
WH2_k127_1803019_2 glutamine amidotransferase K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001895 284.0
WH2_k127_1803019_3 PFAM HPP family K07168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002186 259.0
WH2_k127_1807104_0 aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 572.0
WH2_k127_1807104_1 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 469.0
WH2_k127_1807104_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 422.0
WH2_k127_1807104_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003228 275.0
WH2_k127_1807104_4 metal-dependent phosphohydrolase 7TM intracellular region K07037 - - 0.000000000000000000000000000000000000000000000000000000000000008182 225.0
WH2_k127_1807104_5 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000005688 211.0
WH2_k127_1807104_6 Colicin V production protein K03558 - - 0.000000000000000000000000000000001509 136.0
WH2_k127_1815657_0 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 516.0
WH2_k127_1815657_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 422.0
WH2_k127_1841151_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.04e-232 721.0
WH2_k127_1841151_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 482.0
WH2_k127_1841151_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 295.0
WH2_k127_1841151_3 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000001653 124.0
WH2_k127_1858577_0 Gtr1/RagA G protein conserved region K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 319.0
WH2_k127_1858577_1 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009078 253.0
WH2_k127_1858577_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000001883 208.0
WH2_k127_1858577_3 belongs to the thioredoxin family - - - 0.0000000000000000000000000000000000000000000000000000001101 206.0
WH2_k127_1860333_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 363.0
WH2_k127_1860333_1 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000004617 177.0
WH2_k127_1860333_2 Nitroreductase family - - - 0.000000000000000000000000000000000002363 138.0
WH2_k127_1860333_3 PFAM Glutaredoxin K06191 - - 0.00000000000000000000000000000000000716 138.0
WH2_k127_1860333_4 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000001105 131.0
WH2_k127_1860967_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 556.0
WH2_k127_1860967_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 537.0
WH2_k127_1860967_10 PFAM peptidase - - - 0.000000000000007783 83.0
WH2_k127_1860967_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 517.0
WH2_k127_1860967_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 477.0
WH2_k127_1860967_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 443.0
WH2_k127_1860967_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 387.0
WH2_k127_1860967_6 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 352.0
WH2_k127_1860967_7 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 327.0
WH2_k127_1860967_8 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000008551 184.0
WH2_k127_1860967_9 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000703 170.0
WH2_k127_1864104_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 507.0
WH2_k127_1864104_1 Protein of unknown function (DUF1003) - - - 0.00000000000000001621 84.0
WH2_k127_1864810_0 Belongs to the OprB family K07267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001271 267.0
WH2_k127_1864810_1 Immunoglobulin-like domain of bacterial spore germination - - - 0.000000000000000000000000000000000000004509 158.0
WH2_k127_1864810_3 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000005882 114.0
WH2_k127_1864810_4 - - - - 0.000000000000000000001389 99.0
WH2_k127_1868552_0 Transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 539.0
WH2_k127_1871357_0 membrane K08978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 299.0
WH2_k127_1871357_1 regulatory protein, FmdB family - - - 0.00000000000000001258 86.0
WH2_k127_1871357_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000001378 67.0
WH2_k127_1871357_3 Protein of unknown function (DUF3108) - - - 0.00000000002165 74.0
WH2_k127_1871357_4 - - - - 0.000539 43.0
WH2_k127_1894216_0 PFAM CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 465.0
WH2_k127_1894216_1 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 362.0
WH2_k127_1894216_2 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 289.0
WH2_k127_190145_0 TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0 1076.0
WH2_k127_190145_1 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 556.0
WH2_k127_190145_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 410.0
WH2_k127_190145_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 298.0
WH2_k127_190145_4 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.000000000000000000000000000000000000000000000000001541 188.0
WH2_k127_190145_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000004442 146.0
WH2_k127_190145_6 Protein conserved in bacteria - - - 0.0001945 46.0
WH2_k127_1932410_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 567.0
WH2_k127_1937130_0 Proton-conducting membrane transporter K12141 - - 7.681e-218 685.0
WH2_k127_1937130_1 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 455.0
WH2_k127_1937130_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 318.0
WH2_k127_1937130_3 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002854 258.0
WH2_k127_1937130_4 Proton-conducting membrane transporter K12137 - - 0.000000000000000000000000002977 112.0
WH2_k127_1962821_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 3.059e-283 887.0
WH2_k127_1975242_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 558.0
WH2_k127_1975242_1 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 299.0
WH2_k127_1976999_0 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 441.0
WH2_k127_1976999_1 Carbon starvation protein K06200 - - 0.00000000000000000000000006134 110.0
WH2_k127_1987906_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.661e-226 737.0
WH2_k127_1987906_1 denitrification pathway - - - 3.655e-203 638.0
WH2_k127_1987906_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 449.0
WH2_k127_1987906_3 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.000001216 50.0
WH2_k127_2007779_0 PFAM Histone deacetylase K04768 - - 2.704e-210 661.0
WH2_k127_2007779_1 class II (D K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 350.0
WH2_k127_2007779_2 TIGRFAM arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 348.0
WH2_k127_2007779_3 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000000000000000000000000000000000000001335 213.0
WH2_k127_2007779_4 PFAM Lytic K08309 - - 0.0000000000000000000000000000000000000000000000000002673 192.0
WH2_k127_2007779_5 PFAM Hydantoinase oxoprolinase - - - 0.000000000000000007103 85.0
WH2_k127_2013822_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 494.0
WH2_k127_2013822_1 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000007681 235.0
WH2_k127_203767_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1105.0
WH2_k127_2075914_0 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 426.0
WH2_k127_2075914_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 335.0
WH2_k127_2075914_2 PFAM inositol monophosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
WH2_k127_2075914_3 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003427 241.0
WH2_k127_2075914_4 PFAM cytochrome c class III - - - 0.00001872 47.0
WH2_k127_2077207_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 506.0
WH2_k127_2077207_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001138 253.0
WH2_k127_2077207_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001493 232.0
WH2_k127_2077207_3 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000001545 215.0
WH2_k127_2077207_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000001045 199.0
WH2_k127_2077207_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000001231 177.0
WH2_k127_2077207_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000007139 181.0
WH2_k127_2115758_0 PFAM TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 408.0
WH2_k127_2115758_1 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 327.0
WH2_k127_2115758_2 Cold shock protein domain K03704 - - 0.0000000000000000000000000001982 115.0
WH2_k127_2115758_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00001425 47.0
WH2_k127_2164911_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905 - 6.2.1.13 4.505e-240 762.0
WH2_k127_2164911_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 403.0
WH2_k127_2164911_2 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 364.0
WH2_k127_218460_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000004413 207.0
WH2_k127_218460_1 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000001983 159.0
WH2_k127_218460_2 Domain of unknown function (DUF4398) - - - 0.0000000000000009321 82.0
WH2_k127_218460_3 PFAM EAL domain - - - 0.0000000000138 67.0
WH2_k127_218460_4 Diguanylate cyclase - - - 0.0000000005207 63.0
WH2_k127_2190575_0 Conserved region in glutamate synthase K22083 - 2.1.1.21 0.0 1366.0
WH2_k127_2190575_1 Glutamine amidotransferase domain K22081 - 2.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 533.0
WH2_k127_2190575_2 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003139 267.0
WH2_k127_2217005_0 glutamate synthase - - - 3.721e-201 630.0
WH2_k127_2217005_1 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 498.0
WH2_k127_2217005_2 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 450.0
WH2_k127_2217005_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 395.0
WH2_k127_2217005_4 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 368.0
WH2_k127_2217005_5 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 342.0
WH2_k127_2217005_6 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000008624 192.0
WH2_k127_2217005_7 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000008044 113.0
WH2_k127_2247342_0 PFAM Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 404.0
WH2_k127_2247342_1 - - - - 0.000008409 48.0
WH2_k127_2248265_0 His Kinase A (phosphoacceptor) domain - - - 1.98e-198 633.0
WH2_k127_2248265_1 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000000000000003757 87.0
WH2_k127_2265502_0 ATP-grasp domain K01955 - 6.3.5.5 0.0 1256.0
WH2_k127_2265502_1 - - - - 0.000000000000000000000000000000000000000000000000000000000004482 214.0
WH2_k127_2265502_2 Carbamoyl-phosphate synthetase large chain domain protein K01958 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000116 206.0
WH2_k127_2265502_3 CYTH K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000009552 192.0
WH2_k127_2265502_4 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.000000000000000000000000000000000000000000000001841 181.0
WH2_k127_2267684_0 Zn-dependent hydrolases of the beta-lactamase fold K13985 - 3.1.4.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 375.0
WH2_k127_2267684_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002328 273.0
WH2_k127_2267684_2 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000001409 98.0
WH2_k127_2272744_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 5.811e-213 676.0
WH2_k127_2272744_1 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.0000000000000000000000000000000000000000000006791 169.0
WH2_k127_2272744_2 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - 0.000000000000000000000000000002555 124.0
WH2_k127_2272744_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000006978 48.0
WH2_k127_2280179_0 CheY-like receiver, AAA-type ATPase, and DNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 566.0
WH2_k127_2280179_1 Adenosine/AMP deaminase K01488,K21053 - 3.5.4.2,3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 332.0
WH2_k127_2283523_0 Uncharacterised conserved protein (DUF2156) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000571 275.0
WH2_k127_2283523_1 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000001208 238.0
WH2_k127_2304084_0 Phosphate acyltransferases K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 433.0
WH2_k127_2304084_1 NIL - - - 0.00000000000000000000000000000000000000000000000000000000000001535 217.0
WH2_k127_2304084_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000007036 79.0
WH2_k127_2335095_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1052.0
WH2_k127_2335853_0 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 447.0
WH2_k127_2335853_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001495 238.0
WH2_k127_2335853_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000002624 231.0
WH2_k127_2335853_3 dihydromethanopterin reductase activity - - - 0.000000000000000000000000000000007199 129.0
WH2_k127_2335853_4 - - - - 0.000000000000000000000000001316 114.0
WH2_k127_2358310_0 nuclease activity K18828 - - 0.00000000000000000000000000000000001972 138.0
WH2_k127_2358310_1 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000001032 91.0
WH2_k127_2358310_2 Protein of unknown function DUF262 - - - 0.00000000000000003237 82.0
WH2_k127_2358310_4 Psort location Cytoplasmic, score 8.96 - - - 0.00001405 48.0
WH2_k127_2373988_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004475 269.0
WH2_k127_2373988_1 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000777 214.0
WH2_k127_2373988_2 histidine kinase A domain protein K02030 - - 0.000000000000000000000000000000000000000000008767 185.0
WH2_k127_2373988_3 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000003246 119.0
WH2_k127_2373988_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000009949 110.0
WH2_k127_2373988_5 Polysaccharide pyruvyl transferase - - - 0.000000007759 68.0
WH2_k127_2376365_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 368.0
WH2_k127_2376365_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006109 276.0
WH2_k127_2376365_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000008472 51.0
WH2_k127_2393294_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000001933 252.0
WH2_k127_2393294_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000001233 216.0
WH2_k127_2393294_2 protein conserved in bacteria K19158 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006379,GO:0006401,GO:0006402,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016458,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0017148,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0042710,GO:0043021,GO:0043024,GO:0043170,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044764,GO:0044877,GO:0045947,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0098795,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000001092 151.0
WH2_k127_2393294_3 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.00000000000000000002905 93.0
WH2_k127_2394990_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000006002 197.0
WH2_k127_2394990_1 PFAM von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000001218 199.0
WH2_k127_2395982_0 Adventurous gliding motility protein R - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009642 256.0
WH2_k127_2395982_1 COG0003 Oxyanion-translocating ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000006404 161.0
WH2_k127_2395982_2 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00000000000000000000000000009021 124.0
WH2_k127_2402999_0 TIGRFAM sulfate adenylyltransferase K00958,K13811 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 568.0
WH2_k127_2402999_1 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001694 266.0
WH2_k127_2402999_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002211 258.0
WH2_k127_2441_0 COG2366 Protein related to penicillin acylase K01434,K07116 - 3.5.1.11,3.5.1.97 4.989e-241 771.0
WH2_k127_2441_1 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000001378 147.0
WH2_k127_2441_2 - - - - 0.0000000000000000000000000001668 119.0
WH2_k127_2441_3 Protein tyrosine serine phosphatase K01104 - 3.1.3.48 0.000000000000004266 77.0
WH2_k127_2444626_0 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 290.0
WH2_k127_2444626_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01576,K01652 - 2.2.1.6,4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000003819 246.0
WH2_k127_2444626_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753,K13818 - 2.7.7.77 0.0000000000000000000000000000000000000000002646 164.0
WH2_k127_2444626_3 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000003558 116.0
WH2_k127_2444626_4 - - - - 0.00000000000000004441 83.0
WH2_k127_2444626_5 Domain of unknown function (DUF4010) - - - 0.000000001607 62.0
WH2_k127_2444626_6 Ferritin-like domain - - - 0.00000007288 61.0
WH2_k127_2466545_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1094.0
WH2_k127_2466545_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 392.0
WH2_k127_247709_0 BadF BadG BcrA BcrD - - - 0.0 1724.0
WH2_k127_2482037_0 formate C-acetyltransferase glycine radical - - - 0.0 1230.0
WH2_k127_2482037_1 transposition, DNA-mediated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 301.0
WH2_k127_2482037_2 Transcriptional regulator, GntR family K05799 - - 0.0000000000000000000000000000000002615 139.0
WH2_k127_248737_0 PFAM Sodium sulphate symporter K14445 - - 2.26e-236 740.0
WH2_k127_248737_1 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 317.0
WH2_k127_2493660_0 PFAM iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 300.0
WH2_k127_2493660_1 alcohol dehydrogenase - - - 0.000000000000000000000000006734 115.0
WH2_k127_2493660_2 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000002737 105.0
WH2_k127_2495987_0 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001291 253.0
WH2_k127_2495987_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000001845 227.0
WH2_k127_2495987_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000003684 115.0
WH2_k127_2495987_3 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K11444 - 2.7.7.65 0.0000000000001028 74.0
WH2_k127_2496815_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 436.0
WH2_k127_2496815_1 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 409.0
WH2_k127_2496815_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000003094 139.0
WH2_k127_2502201_0 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 394.0
WH2_k127_2502201_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 314.0
WH2_k127_2502201_2 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001312 251.0
WH2_k127_250332_0 Sh3 type 3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 331.0
WH2_k127_250332_1 Peptidase family M20/M25/M40 K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000009882 229.0
WH2_k127_250332_2 SEC-C domain protein K09858 - - 0.0000000000000000000000000000000000000000000000000000000003766 205.0
WH2_k127_2512241_0 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 383.0
WH2_k127_2512241_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 331.0
WH2_k127_2512241_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000001323 213.0
WH2_k127_2512241_3 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000004727 173.0
WH2_k127_2525767_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 2.111e-214 677.0
WH2_k127_2525767_1 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 563.0
WH2_k127_2525767_2 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000004894 177.0
WH2_k127_2546289_0 metal-dependent phosphohydrolase HD region - - - 1.597e-215 687.0
WH2_k127_2546289_1 radical SAM domain protein K03716 - 4.1.99.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 276.0
WH2_k127_2546289_2 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000004545 216.0
WH2_k127_2556642_0 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001583 285.0
WH2_k127_2556642_1 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001549 268.0
WH2_k127_2576360_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 411.0
WH2_k127_2576360_1 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 316.0
WH2_k127_2576360_2 lipopolysaccharide transmembrane transporter activity K07058 - - 0.00000000000000000000000000000003841 134.0
WH2_k127_2581431_0 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 310.0
WH2_k127_2581431_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000006045 76.0
WH2_k127_2603723_0 PFAM AMP-dependent synthetase and ligase - - - 1.53e-240 755.0
WH2_k127_2605358_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0 1271.0
WH2_k127_2605358_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.662e-257 804.0
WH2_k127_2634982_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 510.0
WH2_k127_2634982_1 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 431.0
WH2_k127_2634982_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000002459 217.0
WH2_k127_2634982_4 LTXXQ motif family protein - - - 0.0000001937 58.0
WH2_k127_2651527_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002073 250.0
WH2_k127_2651527_1 Aconitate B N-terminal domain K01682 - 4.2.1.3,4.2.1.99 0.0000000000000000000000000000001859 123.0
WH2_k127_2651527_2 Histidine kinase - - - 0.00000000000000000004489 96.0
WH2_k127_2651527_3 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000001004 63.0
WH2_k127_2660127_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 409.0
WH2_k127_2660127_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 346.0
WH2_k127_2660127_2 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000001043 227.0
WH2_k127_2660127_3 - - - - 0.000000000000000000000000000000239 134.0
WH2_k127_2660127_4 Transcriptional regulator - - - 0.0000000001188 67.0
WH2_k127_2669203_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.263e-281 872.0
WH2_k127_2669203_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.265e-277 862.0
WH2_k127_2669203_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000008992 241.0
WH2_k127_2669203_3 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000964 233.0
WH2_k127_2669203_4 Prolyl oligopeptidase family K06889,K07397 - - 0.00000000000005592 73.0
WH2_k127_2679175_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 516.0
WH2_k127_2679175_1 PFAM Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 472.0
WH2_k127_2679175_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 406.0
WH2_k127_2679175_3 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 353.0
WH2_k127_2679175_4 PFAM Silent information regulator protein Sir2 K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 327.0
WH2_k127_2679175_5 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 292.0
WH2_k127_2679175_6 L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 292.0
WH2_k127_2679175_7 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000005752 128.0
WH2_k127_2679175_8 - - - - 0.00000000000001899 75.0
WH2_k127_2683295_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.851e-204 640.0
WH2_k127_2683295_1 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 385.0
WH2_k127_2683295_2 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000202 188.0
WH2_k127_2683295_3 Nucleotidyltransferase domain - - - 0.000000000000000000000000000000000002906 139.0
WH2_k127_2689093_0 Adenine deaminase C-terminal domain K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 616.0
WH2_k127_2689093_1 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000169 275.0
WH2_k127_2689093_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.00000000000000000000000000000000000000000000000000000000000002859 221.0
WH2_k127_2689093_3 - - - - 0.00000000000000000000000000000513 119.0
WH2_k127_2689093_4 geranylgeranyl reductase K21401 - 1.3.99.38 0.00000003222 65.0
WH2_k127_2689093_5 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.00000006123 56.0
WH2_k127_2690854_0 histidine kinase A domain protein - - - 1.616e-214 700.0
WH2_k127_2690854_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 534.0
WH2_k127_2690854_2 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 527.0
WH2_k127_2690854_3 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K04488,K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 406.0
WH2_k127_2690854_4 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000009322 155.0
WH2_k127_2694639_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000003049 190.0
WH2_k127_2694639_1 Protein of unknown function (DUF1318) - - - 0.0000003037 53.0
WH2_k127_2695952_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000006172 207.0
WH2_k127_2695952_1 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000001951 173.0
WH2_k127_2697029_0 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 344.0
WH2_k127_2697029_1 PFAM dihydropteroate synthase DHPS K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000005965 192.0
WH2_k127_2697029_2 4Fe-4S single cluster domain K05337 - - 0.000000000000000000000000005867 110.0
WH2_k127_2702448_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 1.445e-269 841.0
WH2_k127_2702448_1 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 443.0
WH2_k127_2706105_0 PFAM peptidase K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 492.0
WH2_k127_2706105_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 397.0
WH2_k127_2706105_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 396.0
WH2_k127_2706105_3 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 351.0
WH2_k127_2706105_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000008473 143.0
WH2_k127_2706105_5 TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA - - - 0.000000000000000000000000000000000004447 140.0
WH2_k127_2706105_7 - - - - 0.000000000000000000006529 95.0
WH2_k127_2718333_0 Predicted membrane protein (DUF2232) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002141 259.0
WH2_k127_2718333_1 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000003549 151.0
WH2_k127_2718333_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000003884 57.0
WH2_k127_2722873_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1021.0
WH2_k127_2722873_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 472.0
WH2_k127_2722873_2 PFAM inner-membrane translocator K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 425.0
WH2_k127_2722873_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 421.0
WH2_k127_2722873_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000003314 126.0
WH2_k127_2737972_0 oxidoreductase activity - - - 8.006e-233 741.0
WH2_k127_2737972_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 343.0
WH2_k127_2737972_2 transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000002137 237.0
WH2_k127_2780605_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1059.0
WH2_k127_2780605_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 6.453e-225 718.0
WH2_k127_2780605_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000243 214.0
WH2_k127_2780605_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000009273 158.0
WH2_k127_2804975_0 Serine Threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 548.0
WH2_k127_2812452_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 9.751e-199 633.0
WH2_k127_2812452_1 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000005595 135.0
WH2_k127_2829991_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.14e-241 756.0
WH2_k127_2829991_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000006149 195.0
WH2_k127_2849822_0 chondroitin AC lyase activity K00694,K01210,K03292 - 2.4.1.12,3.2.1.58 9.815e-306 952.0
WH2_k127_2849822_1 Pfam Glycosyl transferase family 2 - - - 0.00002569 47.0
WH2_k127_2865220_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 605.0
WH2_k127_2865220_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 457.0
WH2_k127_2865220_2 coenzyme F420-1:gamma-L-glutamate ligase activity K21785 GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 368.0
WH2_k127_2865220_3 TIGRFAM methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003918 280.0
WH2_k127_2865220_4 PFAM Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000002525 268.0
WH2_k127_2865220_5 o-acetylhomoserine K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000009885 208.0
WH2_k127_2865220_6 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000001991 199.0
WH2_k127_2865220_7 - - - - 0.0000000000000000000000000000000003646 135.0
WH2_k127_2865220_8 Protein of unknown function (DUF3313) - - - 0.00000000000001587 82.0
WH2_k127_2875174_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 3.425e-202 637.0
WH2_k127_2875174_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 295.0
WH2_k127_2875174_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 296.0
WH2_k127_2875174_3 Anthranilate synthase component I domain protein K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000001575 220.0
WH2_k127_2875703_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 577.0
WH2_k127_2875703_1 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 325.0
WH2_k127_2875703_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007774 261.0
WH2_k127_2894029_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000001887 264.0
WH2_k127_2894029_1 phosphohydrolase - - - 0.0000000000000000000005157 108.0
WH2_k127_2894029_2 Protein of unknown function (DUF3124) - - - 0.00000000000000000006856 91.0
WH2_k127_2904110_0 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000157 202.0
WH2_k127_2904110_1 metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000007238 131.0
WH2_k127_2922419_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 550.0
WH2_k127_2922419_1 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 419.0
WH2_k127_2922419_2 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003492 257.0
WH2_k127_2922419_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000177 223.0
WH2_k127_2993968_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.73e-276 861.0
WH2_k127_2993968_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 384.0
WH2_k127_2993968_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 349.0
WH2_k127_2993968_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000002115 112.0
WH2_k127_3006418_0 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 376.0
WH2_k127_3006418_1 TIGRFAM DNA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001033 209.0
WH2_k127_300657_0 MMPL family K07003 - - 1.71e-305 959.0
WH2_k127_300657_1 PFAM molybdopterin oxidoreductase K00123,K05299 - 1.17.1.10,1.17.1.9 4.245e-276 856.0
WH2_k127_300657_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 7.2e-224 702.0
WH2_k127_300657_3 PFAM TrkA-N domain K03499 - - 8.508e-197 623.0
WH2_k127_300657_4 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000006352 243.0
WH2_k127_300657_5 2Fe-2S iron-sulfur cluster binding domain K05299 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000002165 209.0
WH2_k127_300657_6 PFAM toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000000000000003632 200.0
WH2_k127_300657_7 Enzyme of the cupin superfamily K06995 - - 0.0000000000000000000000000000000000103 138.0
WH2_k127_3013111_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 520.0
WH2_k127_3013111_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 336.0
WH2_k127_3013111_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000001487 154.0
WH2_k127_3013111_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000344 96.0
WH2_k127_3018239_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 596.0
WH2_k127_3018239_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 572.0
WH2_k127_302057_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1142.0
WH2_k127_302057_1 Protein of unknown function (DUF401) K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 382.0
WH2_k127_302057_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 309.0
WH2_k127_302057_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000269 223.0
WH2_k127_302057_4 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003869 226.0
WH2_k127_302057_5 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000007052 184.0
WH2_k127_302057_6 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000001514 106.0
WH2_k127_302057_7 Belongs to the HesB IscA family - - - 0.000000000000009593 76.0
WH2_k127_3023873_0 arginine decarboxylase K01585 - 4.1.1.19 6.373e-272 844.0
WH2_k127_3023873_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 3.111e-227 707.0
WH2_k127_3023873_2 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 524.0
WH2_k127_3023873_3 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 354.0
WH2_k127_3023873_4 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003829 248.0
WH2_k127_3057910_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 4.677e-233 732.0
WH2_k127_3057910_1 PFAM response regulator receiver K02481,K07712 - - 1.794e-212 669.0
WH2_k127_3057910_2 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 504.0
WH2_k127_3057910_3 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.000000000000000000007915 98.0
WH2_k127_307843_0 oligopeptide transporter, OPT family - - - 3.311e-269 842.0
WH2_k127_307843_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000008568 264.0
WH2_k127_3105953_0 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006671 272.0
WH2_k127_3105953_1 MMPL family K07003 - - 0.0000001387 57.0
WH2_k127_3120864_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 400.0
WH2_k127_3120864_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000009698 197.0
WH2_k127_3120864_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0004604 43.0
WH2_k127_3127560_0 phosphatase 2C K20074 - 3.1.3.16 0.000000000000000000000000000000008194 137.0
WH2_k127_3132734_0 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000006104 217.0
WH2_k127_3138320_0 COG1070 Sugar (pentulose and hexulose) kinases K00854 - 2.7.1.17 2.064e-195 622.0
WH2_k127_3138320_1 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 499.0
WH2_k127_3138320_2 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 442.0
WH2_k127_3146822_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 7.126e-217 678.0
WH2_k127_3146822_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000414 249.0
WH2_k127_3146822_2 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000001666 111.0
WH2_k127_3163087_0 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 7.651e-201 629.0
WH2_k127_3163087_1 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001248 290.0
WH2_k127_3173543_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 2.745e-212 663.0
WH2_k127_3173543_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 447.0
WH2_k127_3173543_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 331.0
WH2_k127_3173543_3 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 311.0
WH2_k127_3173543_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001835 270.0
WH2_k127_3173543_5 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002941 251.0
WH2_k127_3178899_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 486.0
WH2_k127_3178899_1 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 289.0
WH2_k127_3184850_0 MreB/Mbl protein - - - 4.809e-246 771.0
WH2_k127_3184850_1 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 546.0
WH2_k127_3184850_2 GrpE - - - 0.0000000000000000000000007049 106.0
WH2_k127_3244563_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 374.0
WH2_k127_3244563_1 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000001487 269.0
WH2_k127_3244563_2 WHG domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 233.0
WH2_k127_3244563_3 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000000000000002547 184.0
WH2_k127_3244563_4 Cupin domain - - - 0.0000000000000000000000000000000000000002165 154.0
WH2_k127_3244563_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000001837 132.0
WH2_k127_3244563_6 long-chain fatty acid transporting porin activity - - - 0.00000000008703 74.0
WH2_k127_3249022_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004492 267.0
WH2_k127_3249022_1 Pyridine nucleotide-disulphide oxidoreductase domain 2 - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0044464,GO:0055114 - 0.0000000000114 72.0
WH2_k127_3265387_0 PFAM NAD dependent epimerase dehydratase family K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 506.0
WH2_k127_3265387_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000001452 216.0
WH2_k127_3265387_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000004786 78.0
WH2_k127_3265387_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000004919 76.0
WH2_k127_3309975_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1371.0
WH2_k127_3309975_1 TAT (twin-arginine translocation) pathway signal sequence K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000085 284.0
WH2_k127_3309975_2 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000001312 200.0
WH2_k127_3332119_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 5.043e-262 815.0
WH2_k127_3332119_1 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 327.0
WH2_k127_3332119_2 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000001074 205.0
WH2_k127_336495_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 505.0
WH2_k127_336495_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000003882 219.0
WH2_k127_336495_2 acyl-CoA dehydrogenase - - - 0.00009202 45.0
WH2_k127_338141_0 Sodium/hydrogen exchanger family - - - 1.167e-303 934.0
WH2_k127_338141_1 PFAM filamentation induced by cAMP protein Fic - - - 2.838e-234 726.0
WH2_k127_3394323_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 439.0
WH2_k127_3394323_2 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000000000000000000000000000000000007125 155.0
WH2_k127_3394323_3 COG1228 Imidazolonepropionase and related - - - 0.000000000003297 74.0
WH2_k127_3395890_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 3.831e-296 927.0
WH2_k127_3395890_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 310.0
WH2_k127_3395890_2 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000178 252.0
WH2_k127_3395890_3 protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000001217 195.0
WH2_k127_3403967_0 AMP-binding enzyme K01897 - 6.2.1.3 4.694e-275 858.0
WH2_k127_3403967_1 PFAM aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 563.0
WH2_k127_3403967_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 550.0
WH2_k127_3403967_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 430.0
WH2_k127_3403967_4 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 347.0
WH2_k127_3403967_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 303.0
WH2_k127_3403967_6 PFAM Acetyl-CoA hydrolase transferase - - - 0.000000000000000000000000000000000000000000000001347 177.0
WH2_k127_3403967_7 NifU-like domain - - - 0.000000000000000000000000002936 113.0
WH2_k127_3403967_8 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000000000000008065 87.0
WH2_k127_3437224_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.359e-293 907.0
WH2_k127_3437224_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002126 271.0
WH2_k127_3437224_2 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000001265 207.0
WH2_k127_3437224_3 - - - - 0.0000000000000000000000000000000000000000000000000001804 190.0
WH2_k127_3437224_4 PFAM CBS domain K03699 - - 0.000000000000000000000000000000000000000000000001176 177.0
WH2_k127_3437224_5 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000003238 162.0
WH2_k127_3437224_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000004022 148.0
WH2_k127_3437224_7 TonB C terminal K03646,K03832 - - 0.00000000000000000000000002054 120.0
WH2_k127_3437224_8 regulatory protein, FmdB family - - - 0.00000000000000000000000002602 111.0
WH2_k127_3437224_9 Mitochondrial domain of unknown function (DUF1713) - - - 0.000001373 50.0
WH2_k127_343755_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 586.0
WH2_k127_343755_1 AMMECR1 K06990 - - 0.00000000000000000000000000000000000000000000000000000000000002437 218.0
WH2_k127_3439795_0 PFAM peptidase K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 504.0
WH2_k127_3439795_1 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 385.0
WH2_k127_3445146_0 TIGRFAM ATP-dependent helicase HrpA K03578,K03579 - 3.6.4.13 2.692e-248 792.0
WH2_k127_3445146_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000007028 154.0
WH2_k127_3457433_0 COG0332 3-oxoacyl- acyl-carrier-protein synthase III K16872 - 2.3.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 348.0
WH2_k127_3457433_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000004825 115.0
WH2_k127_3476824_0 peptide transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 531.0
WH2_k127_3476824_1 COG1360 Flagellar motor protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 298.0
WH2_k127_3476824_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 294.0
WH2_k127_3476824_3 Protein of unknown function (DUF3348) - - - 0.000000000000000000000000000003208 130.0
WH2_k127_3481036_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 445.0
WH2_k127_3481036_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000002139 134.0
WH2_k127_3481036_2 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000004796 135.0
WH2_k127_3481036_3 Binds directly to 16S ribosomal RNA K02968 - - 0.000000001336 62.0
WH2_k127_3512124_0 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 309.0
WH2_k127_3512124_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 299.0
WH2_k127_3512124_2 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000659 271.0
WH2_k127_3512124_3 - - - - 0.0000000000003817 69.0
WH2_k127_3517549_0 AMP-binding enzyme K01897 - 6.2.1.3 1.302e-194 620.0
WH2_k127_3517549_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000001493 74.0
WH2_k127_3517549_2 Glycosyl transferase family 2 - - - 0.0000005155 55.0
WH2_k127_3538084_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 550.0
WH2_k127_3538084_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 458.0
WH2_k127_3538084_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 358.0
WH2_k127_3538084_3 Glucose inhibited division protein A K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000001241 154.0
WH2_k127_3539668_0 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 339.0
WH2_k127_3539668_1 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 349.0
WH2_k127_3539668_2 FAD dependent oxidoreductase - - - 0.0000000000000000000007173 108.0
WH2_k127_3548309_0 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 599.0
WH2_k127_3548309_1 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 583.0
WH2_k127_3548309_2 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 387.0
WH2_k127_3548309_3 lyase activity - - - 0.0000000000000000000000000000000000000000000000000009529 191.0
WH2_k127_3548309_4 Protein of unknown function (DUF3373) - - - 0.000000000000000000000000000000000002997 156.0
WH2_k127_3548309_5 - - - - 0.00000000000000000000000000001021 122.0
WH2_k127_3548309_6 4Fe-4S single cluster domain K05337 - - 0.000000000000000000001481 94.0
WH2_k127_3550517_0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 8.993e-265 826.0
WH2_k127_3550517_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 392.0
WH2_k127_3567215_0 surface antigen K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 309.0
WH2_k127_3594504_0 Thiolase, C-terminal domain - - - 8.207e-203 637.0
WH2_k127_3594504_1 Transcriptional regulator, TetR family - - - 0.00000000000000000000000000000000000000000000001115 175.0
WH2_k127_3594504_2 Tricorn protease homolog K08676 - - 0.000000000000000001799 85.0
WH2_k127_3594504_3 phenylacetate-CoA ligase Coenzyme F390 synthetase-like protein K01912 - 6.2.1.30 0.00000000000000001773 82.0
WH2_k127_3594504_4 phenylacetate-CoA ligase Coenzyme F390 synthetase-like protein K01912 - 6.2.1.30 0.00000000000005072 72.0
WH2_k127_3604_0 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 6.372e-211 667.0
WH2_k127_3604_1 Isocitrate dehydrogenase K00031 - 1.1.1.42 1.293e-199 629.0
WH2_k127_3604_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 304.0
WH2_k127_3604_3 TIGRFAM Protein of - - - 0.0000000000000000000000000000002149 125.0
WH2_k127_3604_4 phosphoribosylaminoimidazole carboxylase activity K01587 GO:0000082,GO:0000278,GO:0003674,GO:0003824,GO:0004638,GO:0004639,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022402,GO:0034641,GO:0034654,GO:0042440,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0046040,GO:0046112,GO:0046148,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903047 4.1.1.21,6.3.2.6 0.0000000000000003374 85.0
WH2_k127_3604_5 PilZ domain - - - 0.000000004435 63.0
WH2_k127_3604453_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.143e-247 777.0
WH2_k127_3604453_1 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002798 239.0
WH2_k127_3604453_2 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000001236 141.0
WH2_k127_3606713_0 sigma-54 factor interaction domain-containing protein K02667 - - 1.84e-209 659.0
WH2_k127_3606713_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000005354 157.0
WH2_k127_3646940_0 Belongs to the peptidase M16 family K07263 - - 4.609e-219 702.0
WH2_k127_3646940_1 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 354.0
WH2_k127_3646940_2 Protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000299 246.0
WH2_k127_3646940_3 Peptidoglycan-synthase activator LpoB K07337 - - 0.000000000000000000000000000000000000000000000000000000001317 206.0
WH2_k127_3671538_0 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 437.0
WH2_k127_3671538_1 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 347.0
WH2_k127_3671538_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005569 277.0
WH2_k127_3671538_3 Helix-turn-helix domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000501 276.0
WH2_k127_3671538_4 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001094 255.0
WH2_k127_3671538_5 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.0000000000000000000000000000000000000000000000003327 179.0
WH2_k127_3671538_6 Belongs to the UPF0213 family K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.0000000000008957 71.0
WH2_k127_3671538_7 TonB dependent receptor - - - 0.0003721 53.0
WH2_k127_368788_0 PFAM Binding-protein-dependent transport system inner membrane component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 582.0
WH2_k127_368788_1 PFAM Binding-protein-dependent transport system inner membrane component K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 548.0
WH2_k127_368788_2 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 416.0
WH2_k127_368788_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000005555 197.0
WH2_k127_368788_4 Histidine kinase A domain protein - - - 0.00000000001137 76.0
WH2_k127_370742_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.004e-221 698.0
WH2_k127_370742_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 363.0
WH2_k127_370742_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 339.0
WH2_k127_3722110_0 VWA containing CoxE family protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 602.0
WH2_k127_3722110_1 BadF BadG BcrA BcrD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001695 282.0
WH2_k127_3722110_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000002178 237.0
WH2_k127_3722110_3 AAA domain (Cdc48 subfamily) - - - 0.000000000001977 67.0
WH2_k127_3748629_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 524.0
WH2_k127_3748629_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 411.0
WH2_k127_3748629_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 316.0
WH2_k127_3748629_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 295.0
WH2_k127_3748629_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000002627 226.0
WH2_k127_3749738_0 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 514.0
WH2_k127_3749738_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 375.0
WH2_k127_3749738_2 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 293.0
WH2_k127_3749738_3 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000000000000000000002092 220.0
WH2_k127_3749738_4 Belongs to the UPF0296 family K09777 - - 0.0000000000000000000000000001425 117.0
WH2_k127_3749738_5 Belongs to the UPF0434 family K09791 - - 0.00000000000000000000000209 103.0
WH2_k127_3749738_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000007624 93.0
WH2_k127_3749738_7 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000001032 72.0
WH2_k127_3775120_0 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 553.0
WH2_k127_3775120_1 L,D-transpeptidase catalytic domain K21470 - - 0.00000000000000000000000000000000000000000000000193 176.0
WH2_k127_3775120_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.000002057 49.0
WH2_k127_3791949_0 CBS domain K00974 - 2.7.7.72 5.4e-323 1011.0
WH2_k127_3791949_1 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 523.0
WH2_k127_3791949_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000007676 232.0
WH2_k127_3791949_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000007059 221.0
WH2_k127_3791949_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000001124 187.0
WH2_k127_3793638_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000008455 236.0
WH2_k127_3793638_1 PFAM carboxyl transferase K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.0000000000000000000000000234 110.0
WH2_k127_3793638_2 - - - - 0.0000000000000000005242 89.0
WH2_k127_3805685_0 Conserved region in glutamate synthase - - - 9.668e-258 797.0
WH2_k127_3805685_1 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000006778 177.0
WH2_k127_3805685_2 NADH dehydrogenase K00335 - 1.6.5.3 0.00000000000000000000000000000000004707 135.0
WH2_k127_3840185_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.884e-222 706.0
WH2_k127_3840185_1 Bacterial regulatory protein, Fis family - - - 2.076e-194 624.0
WH2_k127_3840185_2 phosphoenolpyruvate-dependent sugar phosphotransferase system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 529.0
WH2_k127_3840185_3 NGG1p interacting factor 3 K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000007186 260.0
WH2_k127_3840185_4 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002658 242.0
WH2_k127_3840185_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000001152 241.0
WH2_k127_3840185_6 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000001214 156.0
WH2_k127_3840185_7 - - - - 0.0000000000000007663 79.0
WH2_k127_3856730_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 558.0
WH2_k127_3856730_1 TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 362.0
WH2_k127_3875593_0 TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 496.0
WH2_k127_3875593_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 394.0
WH2_k127_3875593_2 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 338.0
WH2_k127_3875593_3 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000000000000000000001896 184.0
WH2_k127_3881430_0 PFAM AMP-dependent synthetase and ligase - - - 2.548e-229 723.0
WH2_k127_3881430_1 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 555.0
WH2_k127_3881430_2 Acyl-ACP thioesterase - - - 0.00000000000000000000000000000000000000000000000002139 188.0
WH2_k127_3881850_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 2.185e-271 857.0
WH2_k127_3881850_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 539.0
WH2_k127_3881850_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 308.0
WH2_k127_3881850_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000005958 181.0
WH2_k127_3881850_4 Regulatory protein - - - 0.0000000000000000000000000000000003226 135.0
WH2_k127_3881850_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000001016 109.0
WH2_k127_3942352_0 alpha amylase catalytic - - - 7.945e-254 796.0
WH2_k127_3942352_1 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000003336 119.0
WH2_k127_3942352_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000005111 113.0
WH2_k127_3945395_0 Iron-containing alcohol dehydrogenase K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 441.0
WH2_k127_3945395_1 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001176 259.0
WH2_k127_3945395_2 ankyrin repeat K21440 - - 0.00000000000000000000001367 113.0
WH2_k127_3947688_0 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 8.694e-263 829.0
WH2_k127_3947688_1 response regulator receiver K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 565.0
WH2_k127_3947688_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 385.0
WH2_k127_3947688_3 Domain of unknown function (DUF368) K08974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 373.0
WH2_k127_3947688_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 323.0
WH2_k127_3947688_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000003948 237.0
WH2_k127_3947688_6 PFAM conserved K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000473 201.0
WH2_k127_3947688_7 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000000005226 169.0
WH2_k127_3961811_0 MjaI restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000001741 203.0
WH2_k127_3961811_1 PhoQ Sensor - - - 0.000000003902 68.0
WH2_k127_3961811_2 Cro/C1-type HTH DNA-binding domain - - - 0.000001183 53.0
WH2_k127_3977176_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 545.0
WH2_k127_3977176_1 TIGRFAM histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 477.0
WH2_k127_3977176_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 351.0
WH2_k127_3977176_3 Catalyzes the formation hydroxymethylpyrimidine phosphate from hydroxymethylpyrimidine and the formation of of 4-amino-2-methyl-5-diphosphomethylpyrimidine from hydroxymethylpyrimidine phosphate K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000005642 164.0
WH2_k127_3996396_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 569.0
WH2_k127_3996396_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 398.0
WH2_k127_3996396_2 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 323.0
WH2_k127_3999550_0 PFAM sigma-54 factor interaction domain-containing protein - - - 1.425e-300 948.0
WH2_k127_3999550_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000007664 199.0
WH2_k127_3999550_2 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000001286 94.0
WH2_k127_4025385_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 547.0
WH2_k127_4025385_1 PFAM Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 344.0
WH2_k127_4025385_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 342.0
WH2_k127_4025385_3 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000008993 199.0
WH2_k127_4025385_4 Pas domain - - - 0.000000000000000000006394 100.0
WH2_k127_4025385_5 aspartic-type endopeptidase activity K06985 - - 0.000000009231 68.0
WH2_k127_404740_0 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 403.0
WH2_k127_4052625_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 511.0
WH2_k127_4052625_1 Psort location Cytoplasmic, score 8.87 K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000004774 228.0
WH2_k127_4089788_0 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 367.0
WH2_k127_4089788_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000005514 222.0
WH2_k127_4111249_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 553.0
WH2_k127_4111249_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 299.0
WH2_k127_4126772_0 Glycosyltransferase like family 2 K21349 - 2.4.1.268 1.45e-215 675.0
WH2_k127_4126772_1 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 583.0
WH2_k127_4126772_2 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 497.0
WH2_k127_4126772_3 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 315.0
WH2_k127_4126772_4 mannosylglycerate metabolic process K05947,K07026,K15918 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,2.7.1.31,3.1.3.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 300.0
WH2_k127_4126772_5 PFAM penicillin-binding protein transpeptidase K17838 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001694 266.0
WH2_k127_4134482_0 Flotillin K07192 - - 3.683e-257 800.0
WH2_k127_4134482_1 - - - - 0.000000000000000000000000000000000000000000000000000000000003054 214.0
WH2_k127_4134482_2 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000007062 174.0
WH2_k127_4134482_3 - - - - 0.000000000000000000000000000000000000000005514 156.0
WH2_k127_4134482_4 - - - - 0.00000000000000002221 87.0
WH2_k127_4134482_5 - - - - 0.000000000000001891 80.0
WH2_k127_4146219_0 Acyl transferase domain - - - 0.0 1235.0
WH2_k127_4180274_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 471.0
WH2_k127_4180274_1 - - - - 0.000000000000000000000000114 112.0
WH2_k127_4232176_0 type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 358.0
WH2_k127_4232176_1 General secretion pathway protein C K02452 - - 0.00000000000000000000000000000000000000000000000001342 191.0
WH2_k127_4232176_2 - - - - 0.00000008391 59.0
WH2_k127_4257062_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.313e-281 877.0
WH2_k127_4257062_1 Elongation factor Tu domain 2 K02355 - - 8.327e-272 852.0
WH2_k127_4257062_2 PFAM ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 322.0
WH2_k127_4257062_3 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 291.0
WH2_k127_4257062_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000003834 225.0
WH2_k127_4257062_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000133 91.0
WH2_k127_4271787_0 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 387.0
WH2_k127_4271787_1 Shikimate kinase K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000005204 221.0
WH2_k127_4271787_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000001367 136.0
WH2_k127_4281290_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000448 277.0
WH2_k127_4281290_1 nitrate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000002506 205.0
WH2_k127_4281290_2 PFAM cytochrome c class III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000004114 58.0
WH2_k127_4310295_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 417.0
WH2_k127_4310295_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 339.0
WH2_k127_4320973_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.04e-266 829.0
WH2_k127_4320973_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0003674,GO:0003824,GO:0003882,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.8 0.000000000000002534 89.0
WH2_k127_4320973_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000007142 81.0
WH2_k127_4349806_0 aconitate hydratase K01681 - 4.2.1.3 1.333e-319 996.0
WH2_k127_4349806_1 PFAM isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 387.0
WH2_k127_4349806_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 304.0
WH2_k127_4349806_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000001493 214.0
WH2_k127_4349806_4 Hydrolases of the alpha beta superfamily K06889,K07397 - - 0.00000000000000000000000000000000000000000000001934 180.0
WH2_k127_4355680_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 361.0
WH2_k127_4355680_1 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 348.0
WH2_k127_4355680_2 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 324.0
WH2_k127_4355680_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000002655 235.0
WH2_k127_4371566_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 554.0
WH2_k127_4371566_1 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003087 254.0
WH2_k127_4371566_2 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000001172 216.0
WH2_k127_4371566_3 - - - - 0.000000000000000000000000000000000000000000000006229 175.0
WH2_k127_4373231_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 421.0
WH2_k127_4373231_1 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002415 274.0
WH2_k127_4373725_0 Ammonium Transporter Family K03320 - - 2.849e-211 664.0
WH2_k127_4439892_0 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000922 247.0
WH2_k127_4439892_1 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000009375 154.0
WH2_k127_4439892_2 spectrin binding K15502,K19947 - 1.14.13.225 0.0000000000000000006232 97.0
WH2_k127_4451487_0 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 391.0
WH2_k127_4451487_1 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 313.0
WH2_k127_4451487_2 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000007304 226.0
WH2_k127_4489012_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 371.0
WH2_k127_4508657_0 TIGRFAM PfaD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 358.0
WH2_k127_4508657_1 General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 352.0
WH2_k127_4508657_2 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000004977 211.0
WH2_k127_4508657_3 Prokaryotic N-terminal methylation motif K02459 - - 0.0000000000000000000000000000000000000000000000002368 185.0
WH2_k127_4508657_4 Prokaryotic N-terminal methylation motif K02457 - - 0.00000000000000000000000000000007091 134.0
WH2_k127_4508657_5 Fimbrial assembly family protein K02461 - - 0.0000000000000000000000000000007814 129.0
WH2_k127_4508657_6 Prokaryotic N-terminal methylation motif K02458 - - 0.000000000000000000002399 99.0
WH2_k127_4522012_0 Alanine dehydrogenase/PNT, C-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 561.0
WH2_k127_4522012_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 425.0
WH2_k127_4522012_2 PFAM Aldehyde ferredoxin oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 301.0
WH2_k127_4522695_0 PFAM lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 380.0
WH2_k127_4522695_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 348.0
WH2_k127_4522695_2 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005323 255.0
WH2_k127_4528163_0 Heat shock 70 kDa protein K04043 - - 4.4e-323 998.0
WH2_k127_4528163_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.183e-269 835.0
WH2_k127_4528163_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 440.0
WH2_k127_4528163_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000238 183.0
WH2_k127_4529095_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 426.0
WH2_k127_4529095_1 helix_turn_helix, Lux Regulon K02479 - - 0.00000000000000000000000000000000000000001653 156.0
WH2_k127_4529095_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000002057 77.0
WH2_k127_4623414_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 483.0
WH2_k127_4623414_1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000000000000000000000000000000000000000000000001185 188.0
WH2_k127_4623414_2 - - - - 0.000000000000000000000175 100.0
WH2_k127_4623414_3 - - - - 0.0000001456 57.0
WH2_k127_4640649_0 Belongs to the thiolase family K00626 - 2.3.1.9 9.242e-211 661.0
WH2_k127_4640649_1 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000001003 207.0
WH2_k127_4640649_2 May be involved in recombination - - - 0.000000000000000000000000000000000000000000000000003628 186.0
WH2_k127_4661600_0 Cytochrome c554 and c-prime - - - 2.618e-236 735.0
WH2_k127_4661600_1 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 411.0
WH2_k127_4661600_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 312.0
WH2_k127_4671339_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 583.0
WH2_k127_4671339_1 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 416.0
WH2_k127_4700504_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 316.0
WH2_k127_4700504_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000703 170.0
WH2_k127_4713967_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.00000000000000000000000000000000000000000000008636 170.0
WH2_k127_4713967_1 glyoxalase III activity - - - 0.000000000000000000000000000003844 123.0
WH2_k127_4713967_2 chaperone-mediated protein folding - - - 0.000000000000002693 88.0
WH2_k127_471729_0 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 385.0
WH2_k127_471729_1 PFAM transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000321 219.0
WH2_k127_471729_2 PFAM IS66 Orf2 family protein K07484 - - 0.0000000000000000000000000000000000000000000000001865 183.0
WH2_k127_471729_3 - - - - 0.00000000000000001499 87.0
WH2_k127_471729_4 PFAM Integrase catalytic region - - - 0.00000000004471 68.0
WH2_k127_471729_5 PFAM IstB domain protein ATP-binding protein - - - 0.00000000004487 66.0
WH2_k127_4721547_0 Pfam:DUF377 - - - 1.369e-217 684.0
WH2_k127_4721547_1 beta-1,4-mannooligosaccharide phosphorylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 349.0
WH2_k127_4751275_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 543.0
WH2_k127_4751275_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 454.0
WH2_k127_4751275_10 - - - - 0.00000000001645 68.0
WH2_k127_4751275_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 459.0
WH2_k127_4751275_3 RNA-metabolising metallo-beta-lactamase K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 377.0
WH2_k127_4751275_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 362.0
WH2_k127_4751275_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003444 265.0
WH2_k127_4751275_6 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001683 226.0
WH2_k127_4751275_7 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000001515 155.0
WH2_k127_4751275_8 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000006982 112.0
WH2_k127_4751275_9 Glycosyl hydrolases family 17 - - - 0.000000000000000000001664 94.0
WH2_k127_4751889_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 583.0
WH2_k127_4751889_1 PFAM sodium neurotransmitter symporter K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 470.0
WH2_k127_4751889_2 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000006642 239.0
WH2_k127_4751889_3 - - - - 0.000000000000000001549 88.0
WH2_k127_475512_0 Peptidase M16C associated K06972 - - 0.0 1129.0
WH2_k127_475512_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001199 280.0
WH2_k127_475512_2 Transposase and inactivated derivatives - - - 0.000007517 48.0
WH2_k127_475512_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0004566 43.0
WH2_k127_475533_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 492.0
WH2_k127_475533_2 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000002418 220.0
WH2_k127_4764249_0 serine threonine protein kinase K11912 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001064 280.0
WH2_k127_4764249_1 phosphatase K01090,K20074 - 3.1.3.16 0.0005285 46.0
WH2_k127_4810410_0 PFAM peptidase M29 aminopeptidase II K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 536.0
WH2_k127_4810410_1 Phosphomannose isomerase type I K01809,K01840 - 5.3.1.8,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 410.0
WH2_k127_4810410_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 341.0
WH2_k127_4810410_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001638 262.0
WH2_k127_4810410_4 - - - - 0.000000000000000000000002838 104.0
WH2_k127_4812268_0 Molecular chaperone. Has ATPase activity K04079 - - 1.672e-236 743.0
WH2_k127_4812268_1 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000003187 214.0
WH2_k127_4831471_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0 1194.0
WH2_k127_4831471_1 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 4.369e-194 616.0
WH2_k127_4840_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 458.0
WH2_k127_4840_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 438.0
WH2_k127_4840_2 Cytochrome c-type protein K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000001516 230.0
WH2_k127_484184_0 type IV pilus assembly PilZ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 563.0
WH2_k127_484184_1 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003636 276.0
WH2_k127_484184_2 PFAM CBS domain containing protein - - - 0.00000007674 53.0
WH2_k127_4851043_0 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009612 460.0
WH2_k127_4851043_1 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007025 280.0
WH2_k127_4851043_2 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008045 255.0
WH2_k127_4864275_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000001768 189.0
WH2_k127_488896_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 379.0
WH2_k127_488896_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000008797 209.0
WH2_k127_488896_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000008131 179.0
WH2_k127_494925_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 2.129e-198 624.0
WH2_k127_494925_1 PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 366.0
WH2_k127_494925_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 330.0
WH2_k127_494925_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 301.0
WH2_k127_494925_4 PFAM Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000000000000003957 207.0
WH2_k127_494925_5 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000009648 202.0
WH2_k127_494925_6 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000002985 158.0
WH2_k127_494925_7 Ferritin-like domain - - - 0.00000000000000000000000001197 109.0
WH2_k127_494925_8 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000001372 110.0
WH2_k127_494925_9 - - - - 0.00000000000000007971 87.0
WH2_k127_4961515_0 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 438.0
WH2_k127_4961515_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001879 267.0
WH2_k127_4961515_2 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000000000000000000000000000000000000000056 224.0
WH2_k127_4961515_3 Na+/H+ ion antiporter subunit K05569 - - 0.00000000000000000000000000000000000000000000000000000000006621 209.0
WH2_k127_4961515_4 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.000000000000000000000000000000000000000001012 160.0
WH2_k127_4961515_5 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.000000000000000000000000000000000000000006647 156.0
WH2_k127_4961515_6 Domain of unknown function (DUF4040) - - - 0.000000000000000000000000000000000000002258 149.0
WH2_k127_4961515_7 Universal stress protein family - - - 0.000000000000000000001163 94.0
WH2_k127_4961515_8 Proton-conducting membrane transporter K05568 - - 0.000000000000000000353 88.0
WH2_k127_4961883_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 5.893e-287 881.0
WH2_k127_4961883_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 556.0
WH2_k127_4961883_2 Rhodanese Homology Domain - - - 0.00000000000457 68.0
WH2_k127_4988007_0 GMC oxidoreductase K03333 - 1.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 579.0
WH2_k127_4988007_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001698 270.0
WH2_k127_4988007_2 - - - - 0.0000000006086 64.0
WH2_k127_4989554_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 317.0
WH2_k127_4989554_1 transcriptional regulator - - - 0.0000000000000000000000000000000000002111 147.0
WH2_k127_4989554_2 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000000000000000000173 116.0
WH2_k127_4991841_0 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004552 280.0
WH2_k127_4991841_1 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000005997 139.0
WH2_k127_5000809_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000001799 165.0
WH2_k127_5000809_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000001828 145.0
WH2_k127_5000809_2 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.0000000000000000000153 93.0
WH2_k127_5000809_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000002248 98.0
WH2_k127_5000809_4 SCP-2 sterol transfer family - - - 0.000007858 57.0
WH2_k127_5005068_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 460.0
WH2_k127_5005068_1 Histidine kinase K01769,K11959 - 4.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009006 276.0
WH2_k127_5054287_0 PFAM nucleoside H symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 416.0
WH2_k127_5054287_1 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000001543 229.0
WH2_k127_5054287_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000781 135.0
WH2_k127_5054287_3 Protein of unknown function (DUF1573) - - - 0.000000000000000000211 95.0
WH2_k127_5061671_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 570.0
WH2_k127_5061671_1 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 391.0
WH2_k127_5061671_2 Belongs to the TtcA family K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 306.0
WH2_k127_5061671_3 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 306.0
WH2_k127_5061671_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002661 276.0
WH2_k127_5061671_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 240.0
WH2_k127_5061671_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000001418 191.0
WH2_k127_5061671_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000142 86.0
WH2_k127_5086583_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 344.0
WH2_k127_5086583_1 PFAM MltA K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 292.0
WH2_k127_5086583_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000006608 233.0
WH2_k127_5086583_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000001393 228.0
WH2_k127_5086583_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000002013 213.0
WH2_k127_5086583_5 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000009244 208.0
WH2_k127_5086583_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000001804 149.0
WH2_k127_5086583_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.0000000000000000000004403 100.0
WH2_k127_5089285_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 439.0
WH2_k127_5089285_1 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 355.0
WH2_k127_5089285_2 - - - - 0.0000000000000000000000000000000003372 134.0
WH2_k127_5089285_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00004851 46.0
WH2_k127_5096524_0 Putative Fe-S cluster - - - 3.503e-248 784.0
WH2_k127_5096524_1 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 627.0
WH2_k127_5096524_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 582.0
WH2_k127_5096524_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 333.0
WH2_k127_5108475_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 610.0
WH2_k127_5108475_1 Sh3 type 3 domain protein K01448 - 3.5.1.28 0.0001369 51.0
WH2_k127_5115338_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 452.0
WH2_k127_5115338_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 322.0
WH2_k127_5115338_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000001269 241.0
WH2_k127_5115338_3 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
WH2_k127_5115338_4 Phospholipid methyltransferase - - - 0.000001171 54.0
WH2_k127_5116721_0 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009281 248.0
WH2_k127_5116721_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000002665 98.0
WH2_k127_5120480_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005081 276.0
WH2_k127_5120480_2 dehydrogenase, E1 component K00164 - 1.2.4.2 0.00000000000002618 78.0
WH2_k127_5131183_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 3.4e-235 755.0
WH2_k127_5135194_0 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 377.0
WH2_k127_5135194_1 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008595 246.0
WH2_k127_5135194_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000002641 127.0
WH2_k127_515815_0 cysteine-tRNA ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 324.0
WH2_k127_515815_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000004115 202.0
WH2_k127_515815_2 Peptidase family S51 - - - 0.0007461 50.0
WH2_k127_5169310_0 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 310.0
WH2_k127_5169310_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 261.0
WH2_k127_5169310_2 UPF0210 protein K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000003773 222.0
WH2_k127_5169310_3 PFAM translation initiation factor SUI1 K03113 - - 0.00000000000000000000000000000000000000000005858 162.0
WH2_k127_5169310_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000001653 102.0
WH2_k127_5169310_6 lactoylglutathione lyase activity K08234 - - 0.00000000000001051 79.0
WH2_k127_5173596_0 metal-dependent phosphohydrolase 7TM intracellular region K07037 - - 6.959e-194 619.0
WH2_k127_5173596_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000007087 237.0
WH2_k127_5173596_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000663 133.0
WH2_k127_5184256_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 597.0
WH2_k127_5184256_1 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001824 259.0
WH2_k127_5184256_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000215 224.0
WH2_k127_5184256_3 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000000000000004773 211.0
WH2_k127_5184256_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000006974 167.0
WH2_k127_5197525_0 S1 domain K00243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 338.0
WH2_k127_5197525_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002653 265.0
WH2_k127_5197525_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000004904 177.0
WH2_k127_5197525_3 WHG domain - - - 0.00000000000000000000000000000000000001432 152.0
WH2_k127_5205073_0 PFAM ABC transporter related K15738 - - 1.221e-203 649.0
WH2_k127_5205073_1 PFAM MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005036 225.0
WH2_k127_5205073_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000001741 228.0
WH2_k127_5205073_3 - - - - 0.0000003484 56.0
WH2_k127_5207463_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 378.0
WH2_k127_5207463_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000006867 194.0
WH2_k127_5207463_2 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000001072 94.0
WH2_k127_5208865_0 AAA domain, putative AbiEii toxin, Type IV TA system K20459 - - 0.0000000000000000000000000000000000000000000000000000009224 201.0
WH2_k127_5208865_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000001142 126.0
WH2_k127_522395_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 372.0
WH2_k127_522395_1 competence protein COMEC K02238 - - 0.0000000000000000000005641 106.0
WH2_k127_522395_2 lipopolysaccharide core region biosynthetic process - - - 0.00000000007709 66.0
WH2_k127_522395_3 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000001068 64.0
WH2_k127_522395_4 PilZ domain K02676 - - 0.0000002583 58.0
WH2_k127_5238420_0 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 4.551e-210 663.0
WH2_k127_5238420_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 375.0
WH2_k127_5238420_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000003914 236.0
WH2_k127_5238420_3 Protein kinase domain - - - 0.000000000000000000000000000000000111 143.0
WH2_k127_5246387_0 TIGRFAM TIGR00268 family protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009727 251.0
WH2_k127_5246387_1 PFAM Methyltransferase - - - 0.000000000000000000000005183 108.0
WH2_k127_5246387_2 Membrane - - - 0.000006015 58.0
WH2_k127_5251139_0 cysteinyl-tRNA synthetase K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 1.448e-271 846.0
WH2_k127_5251139_1 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 405.0
WH2_k127_5251139_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000001597 247.0
WH2_k127_5260326_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000004468 233.0
WH2_k127_5260326_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000001542 107.0
WH2_k127_5262951_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003762 274.0
WH2_k127_5262951_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - - 0.0000000000000000000000000000009957 124.0
WH2_k127_5262951_2 Methyltransferase K16868 - 2.1.1.265 0.000003958 59.0
WH2_k127_527070_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006363 271.0
WH2_k127_5293841_0 Domain of unknown function (DUF1848) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 366.0
WH2_k127_5293841_1 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001024 284.0
WH2_k127_5293841_2 - - - - 0.00000000000000000000000000000002614 130.0
WH2_k127_5307797_0 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 318.0
WH2_k127_5307797_1 PFAM ThiJ PfpI domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 301.0
WH2_k127_5307797_2 - - - - 0.0000000000000000000000003117 107.0
WH2_k127_5307797_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000001128 61.0
WH2_k127_5320827_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 595.0
WH2_k127_5320827_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005547 273.0
WH2_k127_5366455_0 Amino acid kinase family K00928 - 2.7.2.4 1.295e-220 693.0
WH2_k127_5366455_1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 333.0
WH2_k127_5366455_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 295.0
WH2_k127_5366455_3 Cytochrome c K00406,K03889,K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006048 280.0
WH2_k127_5366455_4 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.000000000000000000000000000000000000000000000000000000000001653 211.0
WH2_k127_5366455_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.00000000003867 63.0
WH2_k127_5370142_0 Acyl-CoA synthetase AMP-acid ligase K01895 - 6.2.1.1 5.104e-207 659.0
WH2_k127_5370142_1 PFAM HypF finger K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 461.0
WH2_k127_5370142_2 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 327.0
WH2_k127_5374987_0 Bacterial flagellin N-terminal helical region K02397 - - 2.251e-273 856.0
WH2_k127_5374987_1 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000000000000000000000000000000000000000009079 222.0
WH2_k127_5374987_2 A translational regulator that binds mRNA to regulate translation initiation and or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome- binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW K03563 - - 0.00000000000000000000000003161 109.0
WH2_k127_5374987_3 FlaG protein - - - 0.0000000000000000000000002607 108.0
WH2_k127_5384527_0 PFAM Bile acid sodium symporter K03325 - - 6.205e-207 648.0
WH2_k127_5384527_1 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000122 244.0
WH2_k127_5384527_2 Cytochrome C biogenesis protein - - - 0.000000000000000000000000000000000000000000000000000000008026 206.0
WH2_k127_5384527_3 Thioredoxin domain - - - 0.000000000000000000000000000005988 125.0
WH2_k127_5384527_4 - - - - 0.000000000000000000000000003995 117.0
WH2_k127_5415286_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 541.0
WH2_k127_5415286_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 498.0
WH2_k127_5415286_2 signal peptide peptidase SppA K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 327.0
WH2_k127_5415286_3 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 322.0
WH2_k127_5429561_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 462.0
WH2_k127_5429561_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 450.0
WH2_k127_5429561_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000007684 73.0
WH2_k127_5429561_3 HDIG domain protein K06950 - - 0.000000000001055 69.0
WH2_k127_5433887_0 Histidine kinase K02482 - 2.7.13.3 2.252e-246 772.0
WH2_k127_5433887_1 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 578.0
WH2_k127_5433887_2 PFAM sulfate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000005862 208.0
WH2_k127_5433887_3 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000006626 188.0
WH2_k127_5433887_4 PFAM histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000001155 159.0
WH2_k127_5448813_0 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 452.0
WH2_k127_5448813_1 ParB domain protein nuclease K03497 - - 0.0000000000000000000000000000000000000126 153.0
WH2_k127_5448813_2 PilZ domain - - - 0.000000000000000000000000004225 114.0
WH2_k127_5448813_3 PFAM Cyclic nucleotide-binding - - - 0.00000000000001208 78.0
WH2_k127_546302_0 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000601 228.0
WH2_k127_546302_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.000000000000000000000000000000000000000000000000000104 189.0
WH2_k127_546302_2 Domain of unknown function (DUF3332) - - - 0.0000000000000000000000001953 112.0
WH2_k127_546302_3 - - - - 0.000000000000000000000001855 107.0
WH2_k127_546302_4 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000002733 85.0
WH2_k127_547033_0 PFAM aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 599.0
WH2_k127_547033_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 387.0
WH2_k127_547033_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004854 271.0
WH2_k127_547033_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000003338 129.0
WH2_k127_547033_4 O-Antigen ligase K02847 - - 0.0000000000000000000000000004184 128.0
WH2_k127_5488809_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 546.0
WH2_k127_5488809_1 - - - - 0.0000000000000000000000000000001404 128.0
WH2_k127_5488809_2 Sulfotransferase domain - - - 0.0000000000000000000000000007214 121.0
WH2_k127_5492248_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 2.552e-219 691.0
WH2_k127_5492248_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 464.0
WH2_k127_5492248_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000005184 257.0
WH2_k127_5492248_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000003626 138.0
WH2_k127_5492248_4 Domain of unknown function (DUF1844) - - - 0.000000000000000000000005006 105.0
WH2_k127_5510228_0 Thioredoxin-like domain K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000007677 239.0
WH2_k127_5510228_1 Heat shock 70 kDa protein - - - 0.0000000000000000000000000000000000000000000000000000009687 205.0
WH2_k127_5510228_2 PFAM Lytic transglycosylase catalytic - - - 0.0000000000000000000000000000000000000000008407 160.0
WH2_k127_5510228_3 IstB-like ATP binding protein K02315 - - 0.00000000000000000000001058 112.0
WH2_k127_5510228_4 DNA binding - - - 0.00000000001363 73.0
WH2_k127_5510228_5 Replication initiator protein - - - 0.0000000001015 74.0
WH2_k127_5528212_0 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 3.685e-194 611.0
WH2_k127_5528212_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 595.0
WH2_k127_5528212_2 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000001404 128.0
WH2_k127_5539096_0 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 406.0
WH2_k127_5539096_1 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 390.0
WH2_k127_5539096_2 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000001794 237.0
WH2_k127_5539096_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000004975 218.0
WH2_k127_5539096_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000009774 211.0
WH2_k127_5539096_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000000009031 184.0
WH2_k127_5539096_6 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000005251 100.0
WH2_k127_5539096_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000001448 76.0
WH2_k127_5624487_0 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 391.0
WH2_k127_5624487_1 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 375.0
WH2_k127_5624487_2 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004 267.0
WH2_k127_5624487_3 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001027 256.0
WH2_k127_5624487_4 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000001295 244.0
WH2_k127_5624487_5 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000003757 213.0
WH2_k127_5624487_6 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.000000000000000000000001262 105.0
WH2_k127_5624487_7 pfam abc-1 K03688 - - 0.0000000000000009667 78.0
WH2_k127_5631303_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 514.0
WH2_k127_5631303_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 508.0
WH2_k127_5631303_2 dihydromethanopterin reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 466.0
WH2_k127_5631303_3 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000004615 231.0
WH2_k127_5642085_0 HlyD family secretion protein K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 342.0
WH2_k127_5642085_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 329.0
WH2_k127_5642085_2 CRS1_YhbY K07574 - - 0.000000000000000000000000000000000007308 139.0
WH2_k127_5642085_3 outer membrane efflux protein - - - 0.00000000000000000000000000000895 134.0
WH2_k127_5642085_4 Protein of unknown function (DUF3347) K07798 - - 0.0000000000005757 76.0
WH2_k127_5642085_5 AAA ATPase domain - - - 0.0000000904 54.0
WH2_k127_5650774_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 5.65e-320 989.0
WH2_k127_5650774_1 Alcohol dehydrogenase class IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008296 428.0
WH2_k127_5670141_0 DEAD DEAH box helicase - - - 1.37e-274 861.0
WH2_k127_5670141_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 507.0
WH2_k127_5670141_2 PHP-associated - - - 0.0000000000000000000000000000003333 134.0
WH2_k127_5670141_3 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000005158 108.0
WH2_k127_5700158_0 type II secretion system protein E K02454 - - 9.962e-231 723.0
WH2_k127_5700158_1 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 441.0
WH2_k127_5700158_2 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000001156 201.0
WH2_k127_5700158_3 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000003505 115.0
WH2_k127_5700158_4 type IV pilus modification protein PilV K02458 - - 0.000000000000000001436 92.0
WH2_k127_5747171_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 432.0
WH2_k127_5747171_1 PFAM Peptidoglycan-binding domain 1 protein K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 355.0
WH2_k127_5747171_2 Type II secretion system protein B K02451 - - 0.00002261 55.0
WH2_k127_5750449_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 529.0
WH2_k127_5750449_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 300.0
WH2_k127_5764271_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 416.0
WH2_k127_5764271_1 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.000000000000000000000000000000000000000000000000000000000003882 210.0
WH2_k127_57653_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.064e-272 850.0
WH2_k127_57653_1 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 301.0
WH2_k127_57653_2 thiolester hydrolase activity K01990,K06889 GO:0008150,GO:0009987,GO:0051301 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000669 261.0
WH2_k127_577249_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.12e-205 642.0
WH2_k127_577249_1 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 518.0
WH2_k127_5792782_0 glutamate synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001996 274.0
WH2_k127_5792782_1 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000009917 214.0
WH2_k127_5795874_0 Acyl-CoA dehydrogenase type 2 domain - - - 2.431e-227 710.0
WH2_k127_5795874_1 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 537.0
WH2_k127_5795874_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 474.0
WH2_k127_5795874_3 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000865 223.0
WH2_k127_5795874_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000005729 126.0
WH2_k127_5795874_5 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.000000000000000000000000000000388 125.0
WH2_k127_5795874_6 Transcription factor zinc-finger K09981 - - 0.00000000000000000000003736 102.0
WH2_k127_58060_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 554.0
WH2_k127_58060_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 306.0
WH2_k127_58060_2 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000001465 217.0
WH2_k127_58060_3 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.00000000000000000000000000000000000253 143.0
WH2_k127_58060_4 Phosphopantetheine attachment site K02078 - - 0.00000000000000000002646 93.0
WH2_k127_5807269_0 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000021 270.0
WH2_k127_5807269_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000004434 155.0
WH2_k127_5807269_2 - - - - 0.0000001529 59.0
WH2_k127_5808664_0 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000004653 177.0
WH2_k127_5808664_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000002379 98.0
WH2_k127_5808664_2 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000000000000003194 96.0
WH2_k127_5816285_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 535.0
WH2_k127_5816285_1 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 456.0
WH2_k127_5816285_2 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000001645 235.0
WH2_k127_5816285_3 PFAM Abortive infection protein K07052 - - 0.000000000000000739 78.0
WH2_k127_5825504_0 Sigma-54 interaction domain - - - 2.458e-219 687.0
WH2_k127_5825504_1 DsrE/DsrF-like family K06039 - - 0.0000000000000000002328 87.0
WH2_k127_5825504_2 thiosulfate sulfurtransferase activity - - - 0.000001289 52.0
WH2_k127_5849691_0 GXGXG motif - - - 2.119e-203 647.0
WH2_k127_5849691_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 379.0
WH2_k127_5849691_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 329.0
WH2_k127_5849691_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004668 265.0
WH2_k127_5849691_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000001913 137.0
WH2_k127_5868480_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 559.0
WH2_k127_5868480_1 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000009113 254.0
WH2_k127_5868480_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000001198 196.0
WH2_k127_5869710_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0 1289.0
WH2_k127_5869710_1 TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0 1115.0
WH2_k127_5869710_2 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 436.0
WH2_k127_5876434_0 TIGRFAM potassium uptake protein, TrkH family K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 537.0
WH2_k127_5876434_1 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 355.0
WH2_k127_5876434_2 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K15327,K15329,K15469 - 2.3.1.39 0.00000000000000000000000000000000000002192 145.0
WH2_k127_589078_0 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 350.0
WH2_k127_589078_1 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000467 135.0
WH2_k127_5912105_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 399.0
WH2_k127_5912105_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 332.0
WH2_k127_5912105_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000006647 229.0
WH2_k127_5912105_3 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000002377 111.0
WH2_k127_593118_0 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003331 273.0
WH2_k127_593118_1 protein kinase activity K11211 - 2.7.1.166 0.000000000000000000000000000002216 128.0
WH2_k127_5933369_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 310.0
WH2_k127_5933369_1 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 299.0
WH2_k127_5933369_2 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 284.0
WH2_k127_5933369_3 PFAM ABC transporter related K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000005986 237.0
WH2_k127_5934463_0 Belongs to the Orn Lys Arg decarboxylase class-II family K01581,K01586 - 4.1.1.17,4.1.1.20 7.511e-199 627.0
WH2_k127_5934463_1 Transglycosylase - - - 0.000000000000007306 78.0
WH2_k127_5954508_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 5.363e-201 637.0
WH2_k127_5954508_1 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 296.0
WH2_k127_5954508_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000008797 203.0
WH2_k127_5954508_3 Domain of unknown function (DUF4412) - - - 0.0000000001082 72.0
WH2_k127_5957741_0 PFAM 2-nitropropane dioxygenase NPD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 585.0
WH2_k127_5957741_1 PFAM Lipocalin-like K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000001892 234.0
WH2_k127_5957741_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000007098 213.0
WH2_k127_5958245_0 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 509.0
WH2_k127_5958245_1 PFAM NADH ubiquinone oxidoreductase, 20 kDa subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 503.0
WH2_k127_5958245_2 PFAM nickel-dependent hydrogenase, large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.00000000000000000006047 90.0
WH2_k127_5976975_0 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000001872 162.0
WH2_k127_5976975_1 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000213 139.0
WH2_k127_5976975_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000003221 116.0
WH2_k127_5982329_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.0 1178.0
WH2_k127_5982329_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 8.366e-275 870.0
WH2_k127_5982329_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 4.133e-271 837.0
WH2_k127_5982329_3 TIGRFAM ammonium transporter K03320 - - 1.683e-203 641.0
WH2_k127_5982329_4 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 284.0
WH2_k127_5982329_5 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000003232 183.0
WH2_k127_5982329_6 Regulatory protein GntR HTH K05799 - - 0.0000000000000000000000002092 115.0
WH2_k127_5984247_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1439.0
WH2_k127_602659_0 His Kinase A (phosphoacceptor) domain - - - 1.344e-199 653.0
WH2_k127_602659_1 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 309.0
WH2_k127_602659_2 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000005958 195.0
WH2_k127_602659_3 Salt-induced outer membrane protein K07283 - - 0.00000000000000003737 90.0
WH2_k127_6050096_0 PFAM formate nitrite transporter K06212,K21993 - - 2.022e-217 681.0
WH2_k127_6050096_1 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 418.0
WH2_k127_6050096_2 Catalyzes the synthesis of activated sulfate K00860,K00958 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006739 279.0
WH2_k127_6050096_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002966 278.0
WH2_k127_6050096_4 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000006778 227.0
WH2_k127_6050096_5 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000009596 145.0
WH2_k127_6059045_0 TIGRFAM thiamine biosynthesis protein ThiC K22466 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.23 1.32e-229 717.0
WH2_k127_6059045_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 455.0
WH2_k127_6059045_2 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000000000004674 209.0
WH2_k127_6059045_3 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000233 190.0
WH2_k127_6061658_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 595.0
WH2_k127_6061658_1 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005635 271.0
WH2_k127_6061658_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000002785 151.0
WH2_k127_606513_0 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 441.0
WH2_k127_606513_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000008455 182.0
WH2_k127_6068444_0 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 546.0
WH2_k127_6068444_1 TOBE domain K02019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 434.0
WH2_k127_6068444_2 L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000005072 167.0
WH2_k127_6068444_3 - - - - 0.000000000000000000000000000000001488 146.0
WH2_k127_6068444_4 Tim44 - - - 0.0000000000000000001358 92.0
WH2_k127_6072071_0 AcrB/AcrD/AcrF family - - - 0.0 1054.0
WH2_k127_6072071_1 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 611.0
WH2_k127_6072071_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00007058 50.0
WH2_k127_608897_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 493.0
WH2_k127_608897_1 TOBE domain K02019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001796 254.0
WH2_k127_608897_2 Molybdate transporter of MFS superfamily K03321 - - 0.0000000000000000000007736 98.0
WH2_k127_6095346_0 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 493.0
WH2_k127_6095346_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 284.0
WH2_k127_6095346_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000001786 87.0
WH2_k127_6105302_0 TIGRFAM cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 446.0
WH2_k127_6105302_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 423.0
WH2_k127_6105302_2 PFAM GAF domain protein - - - 0.000000000000000000000003261 103.0
WH2_k127_6105302_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000007973 53.0
WH2_k127_6107316_0 PFAM short-chain dehydrogenase reductase SDR - - - 0.0 1304.0
WH2_k127_6107316_1 Belongs to the thiolase family K00626 - 2.3.1.9 1.068e-237 738.0
WH2_k127_6107316_2 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000048 219.0
WH2_k127_6107316_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000001451 173.0
WH2_k127_6107316_4 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000000000007512 131.0
WH2_k127_6107316_5 FabA-like domain K02372 - 4.2.1.59 0.000000000000000002486 88.0
WH2_k127_6124815_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 323.0
WH2_k127_6124815_1 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006065 267.0
WH2_k127_6124815_2 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000005276 246.0
WH2_k127_6124815_3 nuclease activity K06218 - - 0.000000000000000000000000000000000004796 138.0
WH2_k127_6124815_4 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000009392 83.0
WH2_k127_6124815_5 - - - - 0.0000000000000001869 81.0
WH2_k127_6124815_6 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000159 67.0
WH2_k127_6136750_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000001713 149.0
WH2_k127_6136750_1 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000004942 141.0
WH2_k127_6136750_2 ACT domain K01079 - 3.1.3.3 0.00000000000000000000000000000000002389 144.0
WH2_k127_6136750_3 Belongs to the UPF0178 family K09768 - - 0.000000000000002283 78.0
WH2_k127_6152792_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 476.0
WH2_k127_6152792_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 471.0
WH2_k127_6152792_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 446.0
WH2_k127_6152792_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003478 279.0
WH2_k127_6152792_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000007951 252.0
WH2_k127_6152792_5 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000003847 139.0
WH2_k127_6163757_0 glycyl-tRNA synthetase, beta K01879 - 6.1.1.14 2.622e-237 752.0
WH2_k127_6163757_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 6.142e-234 742.0
WH2_k127_6163757_10 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000007041 104.0
WH2_k127_6163757_11 Helix-turn-helix domain K15539 - - 0.000000000041 67.0
WH2_k127_6163757_2 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 530.0
WH2_k127_6163757_3 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 509.0
WH2_k127_6163757_4 PFAM GHMP kinase K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 401.0
WH2_k127_6163757_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 394.0
WH2_k127_6163757_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000008455 236.0
WH2_k127_6163757_7 PFAM purine or other phosphorylase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000003709 222.0
WH2_k127_6163757_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000000148 152.0
WH2_k127_6163757_9 - - - - 0.00000000000000000000000000000000001097 139.0
WH2_k127_6169793_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.874e-257 803.0
WH2_k127_6169793_1 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 2.652e-209 654.0
WH2_k127_6169793_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 490.0
WH2_k127_6169793_3 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004741 261.0
WH2_k127_6169793_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000002504 139.0
WH2_k127_6169793_5 Bacterial SH3 domain K07184 - - 0.000000000001611 74.0
WH2_k127_6173564_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 7.11e-218 684.0
WH2_k127_6182419_0 Carbamoyl-phosphate synthetase large chain oligomerisation K01955 - 6.3.5.5 0.0 1617.0
WH2_k127_6182419_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 548.0
WH2_k127_6182419_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000002425 157.0
WH2_k127_6192159_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 488.0
WH2_k127_6192159_1 Uncharacterised conserved protein (DUF2156) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 359.0
WH2_k127_6192159_2 TRANSCRIPTIONal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005484 248.0
WH2_k127_6192159_3 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000000005593 162.0
WH2_k127_6192159_4 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000001916 156.0
WH2_k127_6192159_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000011 147.0
WH2_k127_6192159_6 Condensation domain K15653 - - 0.00001188 57.0
WH2_k127_6205051_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.342e-198 626.0
WH2_k127_6205051_1 Outer membrane protease K01355,K08477,K08566,K13520 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009279,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0043170,GO:0044238,GO:0044425,GO:0044462,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.23.48,3.4.23.49 0.000000000000003859 79.0
WH2_k127_6209047_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 612.0
WH2_k127_6209047_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 443.0
WH2_k127_6209047_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 435.0
WH2_k127_6209047_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 302.0
WH2_k127_6209047_4 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000003065 221.0
WH2_k127_627393_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1280.0
WH2_k127_627393_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000008771 229.0
WH2_k127_6274254_0 A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 405.0
WH2_k127_6274254_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 386.0
WH2_k127_6274254_2 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000005384 177.0
WH2_k127_6275183_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 306.0
WH2_k127_6275183_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000003736 202.0
WH2_k127_6275183_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000001369 142.0
WH2_k127_6275183_3 HEAT repeats - - - 0.00000000000000000000000000000000001376 150.0
WH2_k127_6277829_0 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 335.0
WH2_k127_6277829_1 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 309.0
WH2_k127_6277829_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000009296 222.0
WH2_k127_6277829_3 - - - - 0.0000000000000000000000000000000000000003004 156.0
WH2_k127_6277829_4 - - - - 0.00000000001788 72.0
WH2_k127_6341451_0 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 567.0
WH2_k127_6341451_1 - - - - 0.00000000000000000000000000000000000000000000002307 173.0
WH2_k127_6341451_2 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000111 162.0
WH2_k127_6341451_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000001072 140.0
WH2_k127_6341451_4 Domain of unknown function (DUF4911) - - - 0.00000000000000218 78.0
WH2_k127_6346225_0 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 511.0
WH2_k127_6346225_1 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0000000000000001643 81.0
WH2_k127_634684_0 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 460.0
WH2_k127_634684_1 PFAM response regulator receiver K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 291.0
WH2_k127_634684_2 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000001049 233.0
WH2_k127_634684_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000002764 129.0
WH2_k127_6363184_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 538.0
WH2_k127_6363184_1 oxidoreductase activity K07114 - - 0.0000000000000005166 90.0
WH2_k127_6365764_0 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 360.0
WH2_k127_6365764_1 Uncharacterised protein family (UPF0227) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 339.0
WH2_k127_6377692_0 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 8.067e-197 623.0
WH2_k127_6377692_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 504.0
WH2_k127_6377692_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 358.0
WH2_k127_6377692_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000399 214.0
WH2_k127_6377692_4 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000001825 176.0
WH2_k127_6377692_5 cellulase activity - - - 0.00000000000001208 80.0
WH2_k127_637866_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 6.612e-233 726.0
WH2_k127_637866_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 538.0
WH2_k127_637866_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 393.0
WH2_k127_637866_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 362.0
WH2_k127_637866_4 KR domain K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 357.0
WH2_k127_637866_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005976 265.0
WH2_k127_637866_6 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004843 260.0
WH2_k127_637866_7 ACT domain - - - 0.0000000000000000000000000000000000000000000000000000001807 197.0
WH2_k127_63928_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 372.0
WH2_k127_63928_1 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000008162 235.0
WH2_k127_63928_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000002895 96.0
WH2_k127_63928_3 Putative DNA-binding domain - - - 0.0008562 43.0
WH2_k127_640300_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 413.0
WH2_k127_640300_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 295.0
WH2_k127_640300_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000008772 190.0
WH2_k127_6405185_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.35e-275 864.0
WH2_k127_6405185_1 epimerase dehydratase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000005975 213.0
WH2_k127_6405185_2 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000003235 143.0
WH2_k127_6405185_3 Protein of unknown function (DUF2892) - - - 0.000000000000000000000002618 103.0
WH2_k127_6405185_4 Heavy-metal-associated domain - - - 0.00000000000000000006252 91.0
WH2_k127_6405345_0 Major royal jelly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 342.0
WH2_k127_6405345_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000001205 265.0
WH2_k127_6419216_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 580.0
WH2_k127_6419216_1 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 380.0
WH2_k127_6419216_2 Dissimilatory sulfite reductase - - - 0.0000000000000000000000000000003596 124.0
WH2_k127_6440667_0 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 364.0
WH2_k127_6440667_1 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001039 263.0
WH2_k127_6440667_2 response regulator, receiver - - - 0.0000000000000000000000000000000003446 136.0
WH2_k127_6440667_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000002331 130.0
WH2_k127_6440667_4 ATP synthase B/B' CF(0) K02109 - - 0.00000000000000000000000000000003674 136.0
WH2_k127_6440667_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000005531 126.0
WH2_k127_6440667_6 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.000000000000000000000000001879 113.0
WH2_k127_6440667_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000008043 106.0
WH2_k127_6440667_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000002088 76.0
WH2_k127_6455523_0 GAF domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 362.0
WH2_k127_6455523_1 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000008789 203.0
WH2_k127_647567_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1121.0
WH2_k127_647567_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000004693 107.0
WH2_k127_6535919_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.88e-284 885.0
WH2_k127_6535919_1 heat shock protein DnaJ domain protein K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 409.0
WH2_k127_6535919_2 PFAM Radical SAM domain protein K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 398.0
WH2_k127_6535919_3 Acetyl-CoA hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 334.0
WH2_k127_6536066_0 sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 555.0
WH2_k127_6536066_1 Proteobacterial lipase chaperone protein - - - 0.00000002452 60.0
WH2_k127_6538931_0 cellulase activity - - - 0.000000000000000000000000000000000000000000000001388 185.0
WH2_k127_6538931_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000006793 171.0
WH2_k127_6538931_2 zinc ion binding - - - 0.00000000000103 73.0
WH2_k127_6561767_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000003292 229.0
WH2_k127_6561767_1 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.000000000000000000000000000000000002895 151.0
WH2_k127_6579278_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 537.0
WH2_k127_6579278_1 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 522.0
WH2_k127_6579278_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 441.0
WH2_k127_6579278_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 373.0
WH2_k127_6579278_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 340.0
WH2_k127_659151_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 489.0
WH2_k127_659151_1 NADH flavin oxidoreductase NADH oxidase K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 462.0
WH2_k127_659151_2 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 382.0
WH2_k127_659151_3 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000002025 163.0
WH2_k127_659151_4 Putative regulatory protein - - - 0.000000000005743 69.0
WH2_k127_659151_5 Belongs to the 'phage' integrase family - - - 0.00001003 50.0
WH2_k127_6600493_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.859e-231 724.0
WH2_k127_6600493_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 410.0
WH2_k127_6600493_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000003431 104.0
WH2_k127_6600493_3 TIGRFAM arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000007073 80.0
WH2_k127_6600493_4 - - - - 0.0000000007791 61.0
WH2_k127_6600493_5 PFAM Sporulation K03749 - - 0.000000009228 66.0
WH2_k127_6628323_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 526.0
WH2_k127_6628323_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 462.0
WH2_k127_6628323_2 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 317.0
WH2_k127_6628323_3 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009405 271.0
WH2_k127_6628323_4 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000002361 228.0
WH2_k127_6628323_5 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000008592 211.0
WH2_k127_6628323_6 - - - - 0.0000000000000000000002297 99.0
WH2_k127_6641177_0 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000086 250.0
WH2_k127_6641177_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000001098 83.0
WH2_k127_6644460_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1057.0
WH2_k127_6644460_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 593.0
WH2_k127_6644460_2 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 528.0
WH2_k127_6644460_3 Gtr1/RagA G protein conserved region K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 327.0
WH2_k127_6644460_4 SMART metal-dependent phosphohydrolase HD region K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003324 273.0
WH2_k127_6644460_5 PFAM ApbE family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002719 266.0
WH2_k127_6644460_6 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000002207 196.0
WH2_k127_6644460_7 - K08086 - - 0.0000000000000000000000000004394 123.0
WH2_k127_6644460_8 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.000000000000000000001141 99.0
WH2_k127_6670714_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.537e-208 657.0
WH2_k127_6670714_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 587.0
WH2_k127_6670714_2 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 396.0
WH2_k127_6670714_3 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 348.0
WH2_k127_6670714_4 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 325.0
WH2_k127_6670714_5 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000000004791 186.0
WH2_k127_6670714_6 YacP-like NYN domain K06962 - - 0.00000000000000000000000000000000000000000000000005087 183.0
WH2_k127_6670714_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000007157 184.0
WH2_k127_6670714_8 Predicted RNA-binding protein - - - 0.0000000000000000009365 91.0
WH2_k127_6677639_0 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 308.0
WH2_k127_6677639_1 Fimbrial assembly protein (PilN) K02461 - - 0.000000000000000000000000000000003766 137.0
WH2_k127_6677639_2 Fimbrial assembly protein (PilN) K02461 - - 0.00000000000000000000000000002145 126.0
WH2_k127_6684167_1 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000001597 218.0
WH2_k127_6684167_2 PFAM YebG family protein K09918 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010165,GO:0010212,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.000000000006376 71.0
WH2_k127_6684167_3 YebG protein K09918 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010165,GO:0010212,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000009289 61.0
WH2_k127_6686657_0 Evidence 5 No homology to any previously reported sequences K08303 - - 1.646e-214 684.0
WH2_k127_6686657_1 prephenate dehydrogenase K04517,K14187 - 1.3.1.12,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 469.0
WH2_k127_6686657_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 332.0
WH2_k127_6686657_3 - - - - 0.00000000000000000000000000000000000000000000000000000000002088 210.0
WH2_k127_6686657_4 PFAM Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000000007332 173.0
WH2_k127_6686657_5 belongs to the Fur family K09825 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141 - 0.000000000000000000000000000000000000000000006598 168.0
WH2_k127_6686657_6 Rubrerythrin - - - 0.0000000000000000000000000000000004018 131.0
WH2_k127_670662_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 472.0
WH2_k127_670662_1 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 385.0
WH2_k127_670662_2 PFAM Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 283.0
WH2_k127_670662_3 Putative zinc- or iron-chelating domain K06940 - - 0.000000308 53.0
WH2_k127_6727354_0 RmuC family K09760 - - 9.283e-224 702.0
WH2_k127_6727354_1 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 595.0
WH2_k127_6727354_2 Acyl-CoA dehydrogenase type 2 domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 521.0
WH2_k127_6727354_3 Belongs to the methyltransferase superfamily K06969,K12297 - 2.1.1.173,2.1.1.191,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 476.0
WH2_k127_6727354_4 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 432.0
WH2_k127_6727354_5 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 420.0
WH2_k127_6727354_6 PFAM NAD dependent epimerase dehydratase family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 413.0
WH2_k127_6740419_0 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003799 256.0
WH2_k127_6740419_1 Hsp33 protein K04083 - - 0.000000000000000000000000000000000000000000000000000000000001288 220.0
WH2_k127_6740419_2 Rubrerythrin - - - 0.000000000000000000000000000000000007069 141.0
WH2_k127_6740419_3 HEAT repeat - - - 0.00002776 57.0
WH2_k127_6746314_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 484.0
WH2_k127_6746314_1 Methylase involved in ubiquinone menaquinone biosynthesis K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000003209 207.0
WH2_k127_6746314_2 - - - - 0.00000000000000000000000000001236 119.0
WH2_k127_6746314_3 PFAM EAL domain - - - 0.0000000005847 61.0
WH2_k127_6754725_0 PFAM acyl-CoA dehydrogenase domain protein - - - 1.881e-219 691.0
WH2_k127_6754725_1 Acyl-CoA dehydrogenase type 2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 408.0
WH2_k127_677127_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 533.0
WH2_k127_677127_1 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 459.0
WH2_k127_677127_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 373.0
WH2_k127_678553_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 5.734e-254 793.0
WH2_k127_678553_1 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 482.0
WH2_k127_678553_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 335.0
WH2_k127_678553_3 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008662 252.0
WH2_k127_678553_4 Belongs to the Fur family K03711 - - 0.00000000000000000000002342 101.0
WH2_k127_6791821_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 426.0
WH2_k127_6791821_1 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000001628 206.0
WH2_k127_6796696_0 Tellurite resistance protein TerB K05801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 273.0
WH2_k127_6796696_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000001142 231.0
WH2_k127_6796696_2 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000004878 214.0
WH2_k127_6825841_0 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 402.0
WH2_k127_6825841_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 388.0
WH2_k127_6825841_2 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 376.0
WH2_k127_6825841_3 ATPase-coupled phosphate ion transmembrane transporter activity K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 368.0
WH2_k127_6825841_4 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 312.0
WH2_k127_6825841_5 negative regulation of phosphate transmembrane transport K01104,K02039,K03741 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 0.00000000000000000000000000000001489 140.0
WH2_k127_6825841_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000001517 94.0
WH2_k127_684472_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 1.039e-200 639.0
WH2_k127_684472_1 TIGRFAM cytochrome c-type biogenesis protein CcsB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 355.0
WH2_k127_684472_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003129 265.0
WH2_k127_684472_3 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000001558 130.0
WH2_k127_6856948_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1042.0
WH2_k127_6856948_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 471.0
WH2_k127_6856948_2 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 417.0
WH2_k127_6856948_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 351.0
WH2_k127_6856948_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 316.0
WH2_k127_6856948_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 282.0
WH2_k127_6856948_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003982 265.0
WH2_k127_6856948_7 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000003881 250.0
WH2_k127_6858942_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847 - 5.4.99.2 0.0 1120.0
WH2_k127_6858942_1 PFAM carboxyl transferase K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 9.916e-209 654.0
WH2_k127_6858942_2 LAO AO transport system K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 423.0
WH2_k127_6858942_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000003631 230.0
WH2_k127_6858942_4 Bacterial regulatory proteins TetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000008018 228.0
WH2_k127_6877658_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.071e-202 638.0
WH2_k127_6877658_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 584.0
WH2_k127_6877658_2 AAA ATPase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 536.0
WH2_k127_6877658_3 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000001384 220.0
WH2_k127_6877658_4 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000002358 153.0
WH2_k127_688589_0 anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1107.0
WH2_k127_688589_1 PFAM Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007883 281.0
WH2_k127_688589_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000003418 269.0
WH2_k127_688589_3 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000006427 244.0
WH2_k127_688589_4 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000002637 191.0
WH2_k127_688589_5 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000000004264 138.0
WH2_k127_688589_6 YGGT family K02221 - - 0.00000000000000000000000000000006092 127.0
WH2_k127_688589_7 - - - - 0.000000000005811 68.0
WH2_k127_6901936_0 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 488.0
WH2_k127_6901936_1 Periplasmic binding protein K07121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 492.0
WH2_k127_6905650_0 4Fe-4S dicluster domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.714e-274 847.0
WH2_k127_6905650_1 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 540.0
WH2_k127_6905650_2 nitrate reductase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001252 280.0
WH2_k127_6905650_3 - - - - 0.000000000000001237 81.0
WH2_k127_6905650_4 - - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000001835 61.0
WH2_k127_6908332_0 von Willebrand factor, type A K07114 - - 2.849e-211 671.0
WH2_k127_6908332_1 Sugar transferase K19428 - - 0.00000000000000000000000001623 117.0
WH2_k127_6916991_0 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 428.0
WH2_k127_6916991_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 294.0
WH2_k127_6916991_2 AsnC-type helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000375 203.0
WH2_k127_6916991_3 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000001602 195.0
WH2_k127_6916991_4 transcriptional regulator - - - 0.000000000000000000000000000000000000000002924 162.0
WH2_k127_6916991_5 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.000000000000000000001346 101.0
WH2_k127_6916991_6 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.0001171 48.0
WH2_k127_6945367_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 501.0
WH2_k127_6945367_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000005339 76.0
WH2_k127_696158_0 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 449.0
WH2_k127_696158_1 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000389 218.0
WH2_k127_696158_2 Belongs to the NqrDE RnfAE family K03613 - - 0.00000000000000000000000000005242 120.0
WH2_k127_696158_3 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 - - 0.00000000002045 64.0
WH2_k127_6967634_0 COG0464 ATPases of the AAA class - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 535.0
WH2_k127_6967634_1 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 411.0
WH2_k127_6967634_10 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000003381 69.0
WH2_k127_6967634_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 344.0
WH2_k127_6967634_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 303.0
WH2_k127_6967634_4 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001266 278.0
WH2_k127_6967634_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003036 255.0
WH2_k127_6967634_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000003522 236.0
WH2_k127_6967634_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000002563 169.0
WH2_k127_6967634_8 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000003885 140.0
WH2_k127_6967634_9 SnoaL-like polyketide cyclase - - - 0.000000000000001979 81.0
WH2_k127_6970536_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 610.0
WH2_k127_6970536_1 Carbamoyl-phosphate synthetase large chain domain protein K01958 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 555.0
WH2_k127_6970536_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 308.0
WH2_k127_6970536_3 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000008771 233.0
WH2_k127_6975787_0 Peptidase family M48 - - - 6.337e-195 615.0
WH2_k127_6975787_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 407.0
WH2_k127_6978334_0 DNA polymerase III, delta' K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 346.0
WH2_k127_6978334_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 306.0
WH2_k127_6978334_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 283.0
WH2_k127_6978334_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 285.0
WH2_k127_6978334_4 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000005344 251.0
WH2_k127_6978334_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000001989 175.0
WH2_k127_6978539_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 507.0
WH2_k127_6978539_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000001752 243.0
WH2_k127_6978539_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000003614 98.0
WH2_k127_6998165_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 461.0
WH2_k127_6998165_1 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000001806 122.0
WH2_k127_6998165_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000005189 53.0
WH2_k127_7021370_0 TIGRFAM branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 519.0
WH2_k127_7021370_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000297 230.0
WH2_k127_7021370_2 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000000001388 173.0
WH2_k127_7021370_3 4Fe-4S binding domain K00171 - 1.2.7.1 0.0000000000000000000000000000000000000002053 152.0
WH2_k127_7021370_4 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000002564 150.0
WH2_k127_7034582_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 463.0
WH2_k127_7034582_1 Pfam:AHS2 - - - 0.0000000000000000000000000000000966 125.0
WH2_k127_7043940_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 392.0
WH2_k127_7043940_1 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.0000000000000000000000007349 106.0
WH2_k127_7053449_0 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 292.0
WH2_k127_7053449_1 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001168 252.0
WH2_k127_7057602_0 AIR synthase related protein, N-terminal domain K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 445.0
WH2_k127_7057602_1 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001424 269.0
WH2_k127_7057602_2 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000000000000000000000002735 203.0
WH2_k127_7069693_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 569.0
WH2_k127_7069693_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 327.0
WH2_k127_7069693_2 transposition, DNA-mediated - - - 0.000006727 48.0
WH2_k127_7085319_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 391.0
WH2_k127_7085319_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 330.0
WH2_k127_7085319_2 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002568 256.0
WH2_k127_7087540_0 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001031 251.0
WH2_k127_7087540_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000001503 193.0
WH2_k127_711302_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002835 258.0
WH2_k127_711302_1 NUBPL iron-transfer P-loop NTPase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001237 258.0
WH2_k127_711302_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003432 243.0
WH2_k127_711302_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000005251 147.0
WH2_k127_711302_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000001717 67.0
WH2_k127_711302_5 Belongs to the 5'-nucleotidase family K08693,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000007461 69.0
WH2_k127_7115105_0 Protein tyrosine kinase K12132 - 2.7.11.1 1.447e-196 626.0
WH2_k127_7115105_1 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 364.0
WH2_k127_7115105_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000007978 176.0
WH2_k127_7115105_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000006828 67.0
WH2_k127_7132230_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 507.0
WH2_k127_7132230_1 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006995 276.0
WH2_k127_7132230_2 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000008388 156.0
WH2_k127_7132230_3 chain release factor K15034 - - 0.0000000000006563 70.0
WH2_k127_713805_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 470.0
WH2_k127_713805_1 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 372.0
WH2_k127_713805_2 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000009335 210.0
WH2_k127_713805_3 - - - - 0.000000000000000000000000000000000000000000000001519 189.0
WH2_k127_713805_4 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000002828 124.0
WH2_k127_713805_5 Glycogen recognition site of AMP-activated protein kinase - - - 0.000000000000000000001171 97.0
WH2_k127_7150180_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 1.334e-251 791.0
WH2_k127_7150180_1 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001265 268.0
WH2_k127_7150180_2 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000001461 122.0
WH2_k127_7206082_0 PFAM ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 314.0
WH2_k127_7206082_1 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007135 282.0
WH2_k127_7206082_2 pfam abc-3 K09816,K09819 - - 0.00000000000000000001721 91.0
WH2_k127_7206082_3 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000106 76.0
WH2_k127_7213036_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.727e-299 926.0
WH2_k127_7213036_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 327.0
WH2_k127_7216136_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 549.0
WH2_k127_7225657_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 537.0
WH2_k127_7225657_1 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 415.0
WH2_k127_7225657_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 364.0
WH2_k127_7225657_3 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 348.0
WH2_k127_7225657_4 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000007592 235.0
WH2_k127_7225657_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000000000000005382 218.0
WH2_k127_7225657_6 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000005806 197.0
WH2_k127_7225657_7 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000003505 185.0
WH2_k127_7225657_8 lipopolysaccharide binding K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.000000000000000000249 95.0
WH2_k127_7225657_9 Lipopolysaccharide-assembly, LptC-related - - - 0.00000000000002319 81.0
WH2_k127_7226333_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 403.0
WH2_k127_7226333_1 - - - - 0.00000000000000000000000000000000000000000000000000228 184.0
WH2_k127_7226333_2 Domain of unknown function (DUF3786) - - - 0.0000000000000000007523 87.0
WH2_k127_7226333_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000007392 66.0
WH2_k127_7247173_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 465.0
WH2_k127_7247173_1 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 426.0
WH2_k127_7247173_2 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 331.0
WH2_k127_7247173_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 307.0
WH2_k127_7247173_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 306.0
WH2_k127_7247173_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000006337 128.0
WH2_k127_7247173_7 - K01865 - 5.4.4.1 0.0002677 46.0
WH2_k127_7254940_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 609.0
WH2_k127_7254940_1 overlaps another CDS with the same product name K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 303.0
WH2_k127_7254940_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 293.0
WH2_k127_7254940_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003225 228.0
WH2_k127_7254940_5 universal stress protein - - - 0.0000000000000000000000000000003443 130.0
WH2_k127_7257546_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 608.0
WH2_k127_7257546_1 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 582.0
WH2_k127_7257546_10 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000111 256.0
WH2_k127_7257546_11 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000002174 172.0
WH2_k127_7257546_12 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000009527 81.0
WH2_k127_7257546_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 511.0
WH2_k127_7257546_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 483.0
WH2_k127_7257546_4 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 441.0
WH2_k127_7257546_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 343.0
WH2_k127_7257546_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002592 279.0
WH2_k127_7257546_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002519 280.0
WH2_k127_7257546_8 PFAM peptidase K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009163 272.0
WH2_k127_7257546_9 PFAM ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001226 259.0
WH2_k127_726396_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000004602 220.0
WH2_k127_726396_1 Domain of unknown function (DUF4404) - - - 0.0000000000000000000000002375 108.0
WH2_k127_726396_2 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.00000331 54.0
WH2_k127_7292022_0 PFAM regulatory protein MerR - - - 0.0000000000000000000000000000000000000000000000000000000000000000007326 235.0
WH2_k127_7292022_1 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000009265 181.0
WH2_k127_7292022_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000001599 110.0
WH2_k127_7311287_0 COGs COG1033 exporter of the RND superfamily protein K07003 - - 0.0000000000000000000000000000000000000007726 167.0
WH2_k127_731506_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 1.316e-314 976.0
WH2_k127_731506_1 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 535.0
WH2_k127_731506_2 4Fe-4S ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 343.0
WH2_k127_731506_3 PFAM Formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000009345 178.0
WH2_k127_7338218_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 408.0
WH2_k127_7338218_1 Protein of unknown function (DUF2804) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 327.0
WH2_k127_7338218_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007679 269.0
WH2_k127_7338218_3 PFAM thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000000000000000007865 181.0
WH2_k127_733873_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.249e-243 757.0
WH2_k127_733873_1 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000001251 136.0
WH2_k127_7352759_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002098 251.0
WH2_k127_7352759_1 molybdopterin-guanine dinucleotide biosynthesis protein K03753,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000005655 235.0
WH2_k127_7352759_2 bacterial (prokaryotic) histone like domain K04764 - - 0.0000000000000000000000000000000000002754 142.0
WH2_k127_7352759_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000001737 55.0
WH2_k127_7355459_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 561.0
WH2_k127_7355459_1 Iron-containing alcohol dehydrogenase K00001,K04072 - 1.1.1.1,1.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007682 289.0
WH2_k127_7355459_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000023 186.0
WH2_k127_7355459_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000006728 170.0
WH2_k127_7358258_0 PFAM NADH-ubiquinone oxidoreductase chain 49kDa K00333,K14090 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001813 264.0
WH2_k127_7358258_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000004846 161.0
WH2_k127_7358258_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding K14091 - - 0.000000000000000000000000000000000008266 140.0
WH2_k127_7371250_0 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 597.0
WH2_k127_7391637_0 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000003501 175.0
WH2_k127_7391637_1 - - - - 0.00000000000000000000000001911 119.0
WH2_k127_7395420_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 528.0
WH2_k127_7395420_1 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 354.0
WH2_k127_7415998_0 chitinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001173 286.0
WH2_k127_7415998_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000002392 192.0
WH2_k127_7415998_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000001137 134.0
WH2_k127_7415998_3 Thioredoxin domain - - - 0.0000000000000003299 79.0
WH2_k127_7458211_0 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 541.0
WH2_k127_7458211_1 PFAM Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 434.0
WH2_k127_7458211_2 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000005012 181.0
WH2_k127_7458211_3 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000001449 136.0
WH2_k127_7458211_4 PFAM Cold-shock K03704 - - 0.000000000000000000000000000003482 120.0
WH2_k127_7458211_5 - - - - 0.00000000000000007075 81.0
WH2_k127_7458211_6 - - - - 0.00000000000006977 73.0
WH2_k127_7473126_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 546.0
WH2_k127_7473126_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 435.0
WH2_k127_7473126_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000005984 221.0
WH2_k127_7473126_3 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000002339 207.0
WH2_k127_7491868_0 Putative RNA methylase family UPF0020 K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 369.0
WH2_k127_7491868_1 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003029 271.0
WH2_k127_7491868_2 Dihydroneopterin aldolase - - - 0.000000009546 57.0
WH2_k127_7491868_3 Membrane - - - 0.000002242 58.0
WH2_k127_7500847_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 1.403e-202 637.0
WH2_k127_7500847_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 543.0
WH2_k127_7500847_2 Dehydrogenase E1 component K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 443.0
WH2_k127_7500847_3 Sterol carrier protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 289.0
WH2_k127_7511171_0 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000000000004487 224.0
WH2_k127_7511171_1 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000387 194.0
WH2_k127_7511171_2 - - - - 0.000000000000000000000000000005269 120.0
WH2_k127_7511171_3 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000505 116.0
WH2_k127_7511171_4 Rubrerythrin - - - 0.000000000000000000004151 94.0
WH2_k127_7511171_5 - - - - 0.00000000000000002358 84.0
WH2_k127_7521603_0 Receptor family ligand binding region K01999 - - 1.301e-248 771.0
WH2_k127_7521603_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 390.0
WH2_k127_7521603_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001471 279.0
WH2_k127_7521603_3 Planctomycete cytochrome C - - - 0.0000004037 55.0
WH2_k127_7522711_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 1.171e-217 685.0
WH2_k127_7522711_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 254.0
WH2_k127_7522711_2 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000009131 192.0
WH2_k127_7522711_3 MASE2 domain - - - 0.0000000000000000000000000000000000000002659 172.0
WH2_k127_7522711_4 PilZ domain - - - 0.0000000000000000000000000000000008349 136.0
WH2_k127_7524495_0 4Fe-4S dicluster domain K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 364.0
WH2_k127_7524495_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000007043 238.0
WH2_k127_7524495_2 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000001749 206.0
WH2_k127_7524495_3 Class III cytochrome C family - - - 0.0000000000000000000000000000009261 129.0
WH2_k127_7530796_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.691e-251 785.0
WH2_k127_7530796_1 Protein of unknown function (DUF3124) - - - 0.0000000000000000000000000000000000000000000000001461 181.0
WH2_k127_7530796_2 DDE_Tnp_1-associated - - - 0.00000462 48.0
WH2_k127_7533530_0 permease YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 398.0
WH2_k127_7533530_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 336.0
WH2_k127_7533530_2 permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 323.0
WH2_k127_7533530_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 303.0
WH2_k127_7533530_4 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000003651 166.0
WH2_k127_7533530_5 Phospholipid methyltransferase - - - 0.00000000000000000000001593 104.0
WH2_k127_7546573_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 492.0
WH2_k127_7546573_1 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009768 415.0
WH2_k127_7553168_0 SMART Chromosomal replication initiator DnaA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 571.0
WH2_k127_7553168_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 292.0
WH2_k127_7553168_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000009881 222.0
WH2_k127_7556652_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 442.0
WH2_k127_7556652_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000007979 160.0
WH2_k127_7563764_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 339.0
WH2_k127_7563764_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000005296 190.0
WH2_k127_7563764_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000000003803 178.0
WH2_k127_7563764_3 Protein of unknown function (DUF3024) - - - 0.000000000000000000000000003081 114.0
WH2_k127_7563764_4 PFAM peptidase M55 D-aminopeptidase K16203 - - 0.0000000000000000000004165 108.0
WH2_k127_7573016_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1144.0
WH2_k127_7573016_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 606.0
WH2_k127_7573016_2 unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 417.0
WH2_k127_7573016_3 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 393.0
WH2_k127_7573016_4 Hydrogenase maturation protease K00442 - - 0.00000000000000000000000000000000000000000000000002485 184.0
WH2_k127_7573016_5 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000008688 116.0
WH2_k127_7573016_6 FAD binding domain - - - 0.0000000000000000000005846 100.0
WH2_k127_7585073_0 Alginate O-acetylation protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 491.0
WH2_k127_7585073_1 Sulfotransferase domain - - - 0.000000000001847 69.0
WH2_k127_7612031_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 437.0
WH2_k127_7612031_1 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001107 280.0
WH2_k127_7615917_0 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 1.007e-205 649.0
WH2_k127_7615917_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 445.0
WH2_k127_7636283_0 Amidohydrolase family K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000006793 269.0
WH2_k127_7636283_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000002802 261.0
WH2_k127_7636283_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005484 248.0
WH2_k127_7640621_0 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000000000000000003396 143.0
WH2_k127_7640621_1 methyltransferase activity - - - 0.00000000000000000000000000000005825 134.0
WH2_k127_7640621_2 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000001291 113.0
WH2_k127_7640621_3 Phage integrase family - - - 0.000000000000000000002139 94.0
WH2_k127_7640621_4 Phage integrase family - - - 0.00000000004749 64.0
WH2_k127_7640621_5 - - - - 0.0005311 42.0
WH2_k127_7671585_0 PFAM Polysulphide reductase, NrfD K00185 - - 6.616e-204 640.0
WH2_k127_7671585_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 431.0
WH2_k127_7671585_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 412.0
WH2_k127_7671585_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.000000000000000000000000000000000000000000000000000000000000003037 225.0
WH2_k127_7671585_4 - - - - 0.000000000000002312 76.0
WH2_k127_7674329_0 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 552.0
WH2_k127_7674329_1 chondroitin AC lyase activity K00694,K01210,K03292 - 2.4.1.12,3.2.1.58 0.000000000000000000000000000000000000000000000002388 177.0
WH2_k127_7678220_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 5.949e-208 654.0
WH2_k127_7678220_1 o-acetylhomoserine K01740 - 2.5.1.49 1.247e-204 644.0
WH2_k127_7678220_2 Transfers the fatty acyl group on membrane lipoproteins - - - 0.000000000000000000000000000000008353 136.0
WH2_k127_7696938_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.693e-210 666.0
WH2_k127_7696938_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 443.0
WH2_k127_7696938_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 396.0
WH2_k127_7696938_3 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 361.0
WH2_k127_7696938_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000004338 206.0
WH2_k127_7696938_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000002271 153.0
WH2_k127_7696938_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000002932 148.0
WH2_k127_7696938_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000001292 145.0
WH2_k127_7696938_8 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0000000000000000000000000000000337 129.0
WH2_k127_7704906_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 601.0
WH2_k127_7706666_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1517.0
WH2_k127_7728856_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 336.0
WH2_k127_7728856_1 - - - - 0.0000000000000000000000000000000000000000000298 170.0
WH2_k127_7737169_0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 475.0
WH2_k127_7737169_1 PFAM Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000004166 267.0
WH2_k127_7737169_2 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.000000000002306 68.0
WH2_k127_7750668_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 9.8e-322 1057.0
WH2_k127_7750668_2 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 333.0
WH2_k127_7750668_3 S4 domain K14761 - - 0.000000000000000000005131 94.0
WH2_k127_7757848_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 1.062e-220 686.0
WH2_k127_7757848_1 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 429.0
WH2_k127_7774397_0 Anthranilate synthase component I domain protein K01665 - 2.6.1.85 2.855e-203 649.0
WH2_k127_7774397_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 519.0
WH2_k127_7774397_2 PFAM phosphoesterase RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 389.0
WH2_k127_7774397_3 Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 329.0
WH2_k127_7774397_4 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003366 256.0
WH2_k127_7774397_5 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000003235 250.0
WH2_k127_7774397_6 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000008496 179.0
WH2_k127_779575_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 366.0
WH2_k127_779575_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 312.0
WH2_k127_779575_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007041 262.0
WH2_k127_78068_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 593.0
WH2_k127_78068_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 447.0
WH2_k127_78068_2 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000000000000000000000000000000000000000000000000000000000002928 231.0
WH2_k127_78068_3 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00000000000000000000000000000000000000001896 158.0
WH2_k127_782871_0 type II secretion system K02454 - - 3.674e-251 787.0
WH2_k127_7851029_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.589e-225 718.0
WH2_k127_7851967_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 381.0
WH2_k127_7851967_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 337.0
WH2_k127_7851967_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000003398 267.0
WH2_k127_7851967_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000001193 244.0
WH2_k127_7851967_4 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000000000000000000000000000001013 185.0
WH2_k127_7851967_5 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000002054 121.0
WH2_k127_7851975_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 7.704e-250 779.0
WH2_k127_7851975_1 TIGRFAM histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000003297 183.0
WH2_k127_7890534_1 tigr02147 - - - 0.00000000000000000000000000000000009645 144.0
WH2_k127_7890534_3 Beta propeller domain - - - 0.00002123 55.0
WH2_k127_7895746_0 Type II IV secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 415.0
WH2_k127_7895746_1 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000000000000867 148.0
WH2_k127_7920210_0 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000001543 166.0
WH2_k127_7920210_1 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000002715 111.0
WH2_k127_7920210_2 Membrane - - - 0.000000000000002028 87.0
WH2_k127_793731_0 DEAD-like helicases superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 446.0
WH2_k127_793731_1 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000005273 110.0
WH2_k127_7941350_0 - - - - 0.00000000000000000000000000001656 126.0
WH2_k127_7949785_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.097e-262 825.0
WH2_k127_7949785_1 Fe-S cluster domain protein - - - 2.496e-255 796.0
WH2_k127_7949785_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001831 277.0
WH2_k127_7949785_3 PFAM transcription factor CarD K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008115 241.0
WH2_k127_7949785_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000001172 212.0
WH2_k127_7949785_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000005368 186.0
WH2_k127_7949785_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002155 74.0
WH2_k127_7955679_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 399.0
WH2_k127_7955679_1 shikimate 3-dehydrogenase (NADP+) activity K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000007544 248.0
WH2_k127_7955679_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000002683 201.0
WH2_k127_7974862_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.396e-206 647.0
WH2_k127_7974862_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 445.0
WH2_k127_7974862_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 324.0
WH2_k127_7974862_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000004081 233.0
WH2_k127_7974862_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000002701 114.0
WH2_k127_7974862_6 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000003439 52.0
WH2_k127_7974862_7 - - - - 0.00005684 46.0
WH2_k127_7977919_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 353.0
WH2_k127_7977919_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - 0.000000000000000000000000000000000000000195 155.0
WH2_k127_7977919_2 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000000000000000000000146 119.0
WH2_k127_7977919_3 PFAM ATP synthase I chain - - - 0.00000000000000000000000000001716 123.0
WH2_k127_7977919_4 cheY-homologous receiver domain - - - 0.0008268 51.0
WH2_k127_7980497_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 359.0
WH2_k127_7980497_1 PFAM phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 341.0
WH2_k127_7980497_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002298 269.0
WH2_k127_7980497_3 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000000004278 135.0
WH2_k127_7980497_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000008996 110.0
WH2_k127_7992427_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 515.0
WH2_k127_7992427_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000002132 143.0
WH2_k127_7992427_2 TPR repeat - - - 0.000000000000004924 82.0
WH2_k127_7992427_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00005303 47.0
WH2_k127_7999545_0 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000001614 244.0
WH2_k127_7999545_1 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000007315 235.0
WH2_k127_7999545_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000002964 207.0
WH2_k127_7999545_3 - - - - 0.00000000000000000000000000000002249 139.0
WH2_k127_7999545_4 Tetratricopeptide repeat K07114 - - 0.0000000000002695 80.0
WH2_k127_800914_0 PFAM formate C-acetyltransferase glycine radical K00656,K20038 - 2.3.1.54,4.3.99.4 9.729e-311 968.0
WH2_k127_800914_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000005699 178.0
WH2_k127_8010263_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 507.0
WH2_k127_8010263_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 436.0
WH2_k127_8010263_2 MarC family integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000111 225.0
WH2_k127_8010263_3 Gram-negative-bacterium-type cell outer membrane assembly - - - 0.0000000000000000000000000000005818 125.0
WH2_k127_8010263_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000001803 62.0
WH2_k127_8013111_0 PFAM Radical SAM domain protein K22226 - - 2.373e-216 675.0
WH2_k127_8013111_1 Belongs to the ClpX chaperone family - - - 2.719e-212 676.0
WH2_k127_8013111_2 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 582.0
WH2_k127_8013111_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 531.0
WH2_k127_8013111_4 Dodecin K09165 - - 0.000000000000000000000473 96.0
WH2_k127_8013111_5 Metallo-beta-lactamase superfamily - - - 0.00000000000001608 74.0
WH2_k127_8032333_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 463.0
WH2_k127_8032333_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 462.0
WH2_k127_8032333_2 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 454.0
WH2_k127_8032333_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000006835 124.0
WH2_k127_8032333_4 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000006708 121.0
WH2_k127_8032333_5 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000001518 121.0
WH2_k127_8061905_0 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 391.0
WH2_k127_8061905_1 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 358.0
WH2_k127_8061905_2 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000004355 134.0
WH2_k127_8061905_3 Radical SAM superfamily - - - 0.000000000000007866 78.0
WH2_k127_8078006_0 Elongation factor SelB winged helix K03833 - - 3.239e-249 786.0
WH2_k127_8078006_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 517.0
WH2_k127_8078006_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 405.0
WH2_k127_8078006_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 373.0
WH2_k127_8078006_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 355.0
WH2_k127_8078006_5 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 304.0
WH2_k127_8078006_6 - - - - 0.000000000661 61.0
WH2_k127_810013_0 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 335.0
WH2_k127_810013_1 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 323.0
WH2_k127_810942_0 PFAM Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 570.0
WH2_k127_810942_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 392.0
WH2_k127_810942_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 315.0
WH2_k127_810942_3 Modulates RecA activity K03565 - - 0.00003364 50.0
WH2_k127_8111839_0 Pfam:DUF1446 - - - 1.515e-262 819.0
WH2_k127_8111839_1 PFAM Carbamoyl-phosphate synthase L chain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 374.0
WH2_k127_8111839_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 335.0
WH2_k127_8111839_3 Enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 291.0
WH2_k127_8111839_4 PFAM acyl-CoA dehydrogenase domain protein K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001178 276.0
WH2_k127_8111839_5 Biotin-requiring enzyme - - - 0.0000000000000000000000000000005669 128.0
WH2_k127_8114051_0 PFAM metal-dependent phosphohydrolase HD sub - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 363.0
WH2_k127_8114051_1 cyclic nucleotide-binding K01420,K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006778 264.0
WH2_k127_8114051_2 PFAM Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000005218 155.0
WH2_k127_8114051_3 PFAM 4Fe-4S - - - 0.0000000000000000000000000001314 116.0
WH2_k127_8128913_0 PFAM Protein kinase domain K05385,K12132,K13590 - 2.7.11.1,2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 578.0
WH2_k127_8128913_1 WYL domain - - - 0.00000000000000000000000000003777 118.0
WH2_k127_8129018_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 362.0
WH2_k127_8129018_1 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001034 287.0
WH2_k127_8129018_2 - - - - 0.000000000000000000004668 96.0
WH2_k127_8129018_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000003503 60.0
WH2_k127_8137161_0 Voltage gated chloride channel K03281 - - 6.487e-286 889.0
WH2_k127_8137161_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 474.0
WH2_k127_8137161_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 394.0
WH2_k127_8137161_3 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002706 243.0
WH2_k127_8137161_4 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000001557 239.0
WH2_k127_8137161_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000254 203.0
WH2_k127_8137161_6 cheY-homologous receiver domain - - - 0.0000000000000002992 79.0
WH2_k127_8137161_7 Histidine Phosphotransfer domain - - - 0.0000000000001119 76.0
WH2_k127_8137161_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000001722 53.0
WH2_k127_8155904_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 321.0
WH2_k127_8155904_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001652 282.0
WH2_k127_8155904_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000001222 59.0
WH2_k127_8160195_0 PFAM Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1102.0
WH2_k127_81676_0 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 552.0
WH2_k127_81676_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 426.0
WH2_k127_81676_2 Glucose inhibited division protein A K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 308.0
WH2_k127_8168132_0 Pyridine nucleotide-disulphide oxidoreductase - - - 5.805e-220 690.0
WH2_k127_8168132_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 325.0
WH2_k127_8168132_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000008455 182.0
WH2_k127_8169590_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 524.0
WH2_k127_8182350_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.228e-308 959.0
WH2_k127_8182350_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001448 278.0
WH2_k127_8182350_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000006484 208.0
WH2_k127_8182350_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000001314 134.0
WH2_k127_8182350_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0005346 44.0
WH2_k127_8190856_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1037.0
WH2_k127_8191868_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 524.0
WH2_k127_8191868_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 342.0
WH2_k127_8191868_2 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 285.0
WH2_k127_8191868_3 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000006464 147.0
WH2_k127_8191868_4 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.00000000000000000008997 94.0
WH2_k127_8193760_0 AMP-binding enzyme - - - 6.347e-263 824.0
WH2_k127_8193760_1 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 308.0
WH2_k127_8193760_2 Sigma-54 interaction domain K00575 - 2.1.1.80 0.000000000000000001698 87.0
WH2_k127_8200144_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 422.0
WH2_k127_8200144_1 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000004919 155.0
WH2_k127_8251209_0 PFAM acyl-CoA dehydrogenase domain protein - - - 5.817e-283 879.0
WH2_k127_8251209_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009998 251.0
WH2_k127_8252381_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.557e-284 887.0
WH2_k127_8252381_1 Carbohydrate phosphorylase K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 295.0
WH2_k127_8268577_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 604.0
WH2_k127_8268577_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 327.0
WH2_k127_8268577_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - 0.000000000000000007137 96.0
WH2_k127_8271735_0 8-amino-7-oxononanoate synthase activity K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 427.0
WH2_k127_8271735_1 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.00000000000000000000000000005874 117.0
WH2_k127_8277364_0 General secretory system II protein E domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 372.0
WH2_k127_8277364_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000001814 85.0
WH2_k127_8277364_2 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000001712 65.0
WH2_k127_8285216_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000005532 239.0
WH2_k127_8285216_1 membrane-fusion protein - - - 0.000000000000000000000000000001838 128.0
WH2_k127_8286015_0 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 308.0
WH2_k127_8286015_1 alpha/beta hydrolase fold K22318 - - 0.000000000000000000000000000000000000000000000000000000000000000002174 230.0
WH2_k127_8303688_0 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 2.294e-199 629.0
WH2_k127_8303688_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000000002846 158.0
WH2_k127_8303688_2 - - - - 0.00000000000000000000000000002696 118.0
WH2_k127_8315307_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 351.0
WH2_k127_8315307_1 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000006458 157.0
WH2_k127_8317274_0 AAA-like domain K20530 - - 1.546e-309 949.0
WH2_k127_8317274_1 PFAM Phage regulatory protein Rha (Phage_pRha) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 567.0
WH2_k127_8317274_2 PFAM CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 490.0
WH2_k127_8317274_3 Type IV secretory pathway, VirB2 component (Pilin) K20528 - - 0.000000000000000000000000000000000000000000000000000000000009345 207.0
WH2_k127_8325520_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.235e-304 943.0
WH2_k127_8325520_1 PFAM Pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 4.033e-225 709.0
WH2_k127_8325520_2 Belongs to the aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 476.0
WH2_k127_8325520_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 306.0
WH2_k127_8325520_4 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001032 267.0
WH2_k127_8325520_5 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001887 255.0
WH2_k127_8330443_0 Phosphofructokinase K00895,K21071 - 2.7.1.11,2.7.1.90 2.94e-239 748.0
WH2_k127_8330443_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 558.0
WH2_k127_8330443_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 352.0
WH2_k127_8330443_3 Protein of unknown function DUF134 - - - 0.000000000000000000000000000000000000000000000000000001364 194.0
WH2_k127_834356_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.934e-237 745.0
WH2_k127_834356_1 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 1.561e-224 704.0
WH2_k127_834356_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 5.281e-214 669.0
WH2_k127_834356_3 DNA segregation ATPase, FtsK SpoIIIE family K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 579.0
WH2_k127_834356_4 binding domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 445.0
WH2_k127_834356_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 370.0
WH2_k127_834356_6 flavin adenine dinucleotide binding K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000001219 189.0
WH2_k127_834356_7 - - - - 0.00000000000000000000000000000000009088 135.0
WH2_k127_834356_8 4Fe-4S binding domain - - - 0.00000000000000000000000000001494 118.0
WH2_k127_834356_9 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000003133 120.0
WH2_k127_8355952_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 393.0
WH2_k127_8355952_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 289.0
WH2_k127_8355952_2 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000001846 231.0
WH2_k127_8355952_3 Fis family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002905 179.0
WH2_k127_8355952_4 polysaccharide biosynthetic process - - - 0.0000000000000000000000005066 119.0
WH2_k127_8358630_0 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001979 281.0
WH2_k127_8358630_1 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000002585 254.0
WH2_k127_8358630_3 Putative small multi-drug export protein - - - 0.000000000000000000000000000000000002051 148.0
WH2_k127_8358630_4 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000001893 121.0
WH2_k127_8358630_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000003523 111.0
WH2_k127_8363143_0 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 335.0
WH2_k127_8363143_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000001437 191.0
WH2_k127_8363143_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000001653 81.0
WH2_k127_8363143_3 Sulfatase - - - 0.00000000001161 66.0
WH2_k127_8370624_0 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000001547 213.0
WH2_k127_8370624_1 KR domain - - - 0.0000000000000000000000000000000000000006013 154.0
WH2_k127_8370624_2 KR domain - - - 0.000000000000000000000001805 106.0
WH2_k127_8370624_3 - - - - 0.000000000000000000009395 98.0
WH2_k127_8370624_4 - - - - 0.00000000000005152 77.0
WH2_k127_8370624_5 - - - - 0.00008661 46.0
WH2_k127_8380012_0 Bacterial periplasmic substrate-binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 620.0
WH2_k127_8383130_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 2.412e-217 681.0
WH2_k127_8383130_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 362.0
WH2_k127_8383130_2 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000164 251.0
WH2_k127_8392010_0 Acetyl-CoA hydrolase transferase N-terminal domain - - - 7.269e-260 812.0
WH2_k127_8392010_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007849 268.0
WH2_k127_840413_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 611.0
WH2_k127_840413_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 399.0
WH2_k127_840413_2 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 358.0
WH2_k127_841461_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 8.279e-296 931.0
WH2_k127_841461_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000002068 235.0
WH2_k127_841461_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000001623 216.0
WH2_k127_841461_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001999 76.0
WH2_k127_8415273_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 399.0
WH2_k127_8415273_1 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000008225 218.0
WH2_k127_8415273_2 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000002411 222.0
WH2_k127_8415273_3 protein tyrosine kinase activity K08252 - 2.7.10.1 0.000000000000003879 78.0
WH2_k127_8421325_0 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 419.0
WH2_k127_8421325_1 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000000000003934 99.0
WH2_k127_8421325_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.0003462 48.0
WH2_k127_8423049_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 310.0
WH2_k127_8423049_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006942 273.0
WH2_k127_8423049_2 - - - - 0.000000000000000000000000001803 115.0
WH2_k127_8490296_0 Acyl-CoA dehydrogenase type 2 domain - - - 4.011e-218 683.0
WH2_k127_8490296_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 301.0
WH2_k127_8490296_2 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001151 260.0
WH2_k127_8490296_3 - - - - 0.000000000000000000000000000000000000000001434 158.0
WH2_k127_852608_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000227 279.0
WH2_k127_852608_1 Cobalamin synthesis G C-terminus K02189 - 3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000003508 258.0
WH2_k127_852608_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000000008244 244.0
WH2_k127_852608_3 Tetrapyrrole (Corrin/Porphyrin) Methylases K05934 - 2.1.1.131 0.0000000000000000000000000000000000000000000000000000000000000007774 228.0
WH2_k127_852608_4 Precorrin-6x reductase CbiJ/CobK K05895 - 1.3.1.106,1.3.1.54 0.000000000000000000000000000000000000000000000000000000434 202.0
WH2_k127_852608_5 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000003374 191.0
WH2_k127_8531262_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 388.0
WH2_k127_8531262_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000002705 250.0
WH2_k127_8531262_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000007498 191.0
WH2_k127_8531262_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000009122 116.0
WH2_k127_8569011_0 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 8.962e-222 724.0
WH2_k127_8569011_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 586.0
WH2_k127_8569011_2 methyl-accepting chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000388 292.0
WH2_k127_8569011_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000005756 228.0
WH2_k127_8569011_4 Cache domain - - - 0.000000000000000000000000000000000000000000000000000006414 207.0
WH2_k127_8569011_5 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000002267 136.0
WH2_k127_8572079_0 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 1.446e-202 642.0
WH2_k127_8572079_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 364.0
WH2_k127_8572079_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000001087 246.0
WH2_k127_8572079_3 PFAM single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000000000000000000000000000000000000000000002387 212.0
WH2_k127_8572079_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000001985 169.0
WH2_k127_8572079_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000002146 109.0
WH2_k127_8572079_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000213 94.0
WH2_k127_8572079_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000002865 67.0
WH2_k127_8572079_8 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.000001301 51.0
WH2_k127_8600869_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 1.373e-256 803.0
WH2_k127_8600869_1 CoA binding domain K01905,K22224 - 6.2.1.13 0.0000000002108 62.0
WH2_k127_8601140_0 Homeodomain-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 488.0
WH2_k127_8601140_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 289.0
WH2_k127_8601140_2 transposition K07497 - - 0.000000000000000000000000000000000000000001011 159.0
WH2_k127_8601140_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000126 54.0
WH2_k127_8601140_5 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.00000519 49.0
WH2_k127_8615553_0 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 374.0
WH2_k127_8615553_1 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 351.0
WH2_k127_8615553_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K00972 - 2.7.7.23,2.7.7.83 0.0000000000000000000000000000000000000000000000000000000000000001611 226.0
WH2_k127_8620403_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 546.0
WH2_k127_8620403_1 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000002447 121.0
WH2_k127_862948_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1197.0
WH2_k127_862948_1 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 556.0
WH2_k127_862948_2 PFAM peptidase - - - 0.000000000000000000000000000000000000000005148 160.0
WH2_k127_862948_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000306 130.0
WH2_k127_8673709_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 7.063e-243 779.0
WH2_k127_8673709_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 437.0
WH2_k127_8673709_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000009265 246.0
WH2_k127_8673709_3 Catalyzes the insertion of Co(2 ) into sirohydrochlorin K02190 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0016829,GO:0016852,GO:0020037,GO:0022607,GO:0042597,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050897,GO:0051259,GO:0051262,GO:0051266,GO:0065003,GO:0071840,GO:0097159,GO:1901363 4.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000002935 239.0
WH2_k127_8690974_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 493.0
WH2_k127_8690974_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 479.0
WH2_k127_8690974_2 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 287.0
WH2_k127_8690974_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 282.0
WH2_k127_8690974_4 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000001179 242.0
WH2_k127_8690974_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000005225 219.0
WH2_k127_871032_0 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 500.0
WH2_k127_871032_1 Type II secretion system (T2SS), protein M subtype b - - - 0.00000000000000000000000001337 117.0
WH2_k127_871032_2 Fimbrial assembly protein (PilN) K02461 - - 0.000000000000000000006971 97.0
WH2_k127_871032_3 - - - - 0.000293 51.0
WH2_k127_8724378_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 4.095e-230 719.0
WH2_k127_8724378_1 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000249 280.0
WH2_k127_8724378_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000002447 83.0
WH2_k127_8724378_3 4Fe-4S dicluster domain - - - 0.0000000001828 72.0
WH2_k127_8741766_0 PFAM Type II IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 535.0
WH2_k127_8741766_1 Acyl-CoA dehydrogenase type 2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 346.0
WH2_k127_8741766_2 PFAM Type II IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 341.0
WH2_k127_8741766_3 - K09143 - - 0.00000000000000000000000000000000000000000001088 164.0
WH2_k127_8741766_4 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000007041 93.0
WH2_k127_8741766_5 - - - - 0.0000001059 57.0
WH2_k127_8744971_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 433.0
WH2_k127_8744971_1 transport system permease K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 409.0
WH2_k127_8744971_2 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008786 356.0
WH2_k127_8744971_3 branched-chain amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 312.0
WH2_k127_8744971_4 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000005115 149.0
WH2_k127_8746357_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 575.0
WH2_k127_8746357_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 374.0
WH2_k127_8746357_2 PFAM Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 345.0
WH2_k127_8746357_3 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 313.0
WH2_k127_8746452_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000002542 209.0
WH2_k127_8746452_1 Domain of unknown function (DUF4301) - - - 0.00003284 48.0
WH2_k127_8746452_2 Histidine kinase K20976 - - 0.00005674 51.0
WH2_k127_875877_0 TIGRFAM acetylornithine and succinylornithine aminotransferase K00821,K05830,K09251 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575 2.6.1.11,2.6.1.17,2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 334.0
WH2_k127_875877_1 - - - - 0.00000000000000000000000000000000000000000000000000000002601 205.0
WH2_k127_8784132_0 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 5.298e-290 899.0
WH2_k127_8784132_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 601.0
WH2_k127_8784132_2 Domain of unknown function (DUF362) K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 569.0
WH2_k127_8784132_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 429.0
WH2_k127_8784132_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000000005078 230.0
WH2_k127_8784132_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000006773 184.0
WH2_k127_8784132_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000002241 132.0
WH2_k127_8784132_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000004214 66.0
WH2_k127_878455_0 8-amino-7-oxononanoate synthase activity K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 434.0
WH2_k127_878455_1 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000002926 221.0
WH2_k127_878455_2 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000000001393 89.0
WH2_k127_8785484_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 7.636e-210 657.0
WH2_k127_8785484_1 4Fe-4S binding domain K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000003176 211.0
WH2_k127_8785484_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000301 159.0
WH2_k127_879099_0 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 351.0
WH2_k127_879099_1 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000001172 212.0
WH2_k127_879099_2 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.000000000000000000000000000000000000000001621 175.0
WH2_k127_879099_3 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000002178 49.0
WH2_k127_8791161_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 449.0
WH2_k127_8791161_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000003696 167.0
WH2_k127_8791161_2 Pfam Adenylate and Guanylate cyclase catalytic domain K08884 - 2.7.11.1 0.00000000000001779 85.0
WH2_k127_8792169_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000001307 136.0
WH2_k127_8792169_1 metallopeptidase activity K01173,K14645 - - 0.000000000000003616 87.0
WH2_k127_8792169_2 Peptidase family C25 - - - 0.000000000000004841 87.0
WH2_k127_884066_0 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 463.0
WH2_k127_884066_1 ABC transporter, ATP-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000009231 222.0
WH2_k127_884066_3 - - - - 0.00000000000000000000000000000000006673 136.0
WH2_k127_885867_0 PFAM ferredoxin - - - 2.06e-294 915.0
WH2_k127_885867_1 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000001825 130.0
WH2_k127_885867_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000001503 59.0
WH2_k127_8858959_0 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 396.0
WH2_k127_8858959_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000001625 131.0
WH2_k127_8858959_2 toluene tolerance protein - - - 0.000005992 53.0
WH2_k127_8876376_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 492.0
WH2_k127_8876376_1 Histidine kinase A domain protein K02030 - - 0.000000000000000000000000000000000000000000000004773 188.0
WH2_k127_8876376_2 response regulator, receiver - - - 0.00009953 54.0
WH2_k127_8888686_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 334.0
WH2_k127_8888686_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 286.0
WH2_k127_8888686_2 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000006992 213.0
WH2_k127_8888686_3 Domain of unknown function (DUF4445) - - - 0.0000000000000000005435 88.0
WH2_k127_8908202_0 Amino acid permease - - - 1.686e-208 665.0
WH2_k127_9004814_0 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 584.0
WH2_k127_9004814_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 340.0
WH2_k127_9004814_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 338.0
WH2_k127_9004814_3 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003893 226.0
WH2_k127_9004814_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000008659 189.0
WH2_k127_9004814_5 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000008971 160.0
WH2_k127_9004814_6 - - - - 0.00000005062 56.0
WH2_k127_9015053_0 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 326.0
WH2_k127_9015053_1 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000000000000001279 224.0
WH2_k127_9015053_2 - - - - 0.000000000000000001778 91.0
WH2_k127_9015053_3 deoxyhypusine monooxygenase activity - - - 0.0000000001636 71.0
WH2_k127_9030326_0 PHP domain protein - - - 2.336e-233 739.0
WH2_k127_9047685_0 UPF0210 protein K09157 - - 0.00000000000000000000000000000000000000000000000001053 185.0
WH2_k127_9047685_1 Belongs to the UPF0237 family K07166 - - 0.0000000000000000003659 90.0
WH2_k127_9049744_0 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002096 276.0
WH2_k127_9049744_1 von Willebrand factor (vWF) type A domain K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005053 259.0
WH2_k127_9049744_2 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645 - 4.1.2.13 0.00000000000000000000000001417 109.0
WH2_k127_9049744_3 - - - - 0.0000000000000000001827 98.0
WH2_k127_9051269_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 2.179e-254 789.0
WH2_k127_9051269_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 338.0
WH2_k127_9051269_2 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000002517 141.0
WH2_k127_9057651_0 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 1.309e-265 831.0
WH2_k127_9057651_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 454.0
WH2_k127_9057651_2 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 351.0
WH2_k127_9057651_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000004583 176.0
WH2_k127_9057651_4 metallopeptidase activity K01387 - 3.4.24.3 0.000000000006915 79.0
WH2_k127_9057651_5 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.0000000002556 74.0
WH2_k127_910992_0 Bacterial periplasmic substrate-binding proteins - - - 0.0 1141.0
WH2_k127_910992_1 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000005184 71.0
WH2_k127_912045_0 Mechanosensitive ion channel K05802,K22051 GO:0005575,GO:0005623,GO:0005886,GO:0006884,GO:0008150,GO:0008361,GO:0009987,GO:0009992,GO:0016020,GO:0016043,GO:0019725,GO:0030104,GO:0032535,GO:0042592,GO:0044464,GO:0048878,GO:0055082,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 501.0
WH2_k127_912045_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 368.0
WH2_k127_9138280_0 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 388.0
WH2_k127_9139122_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.772e-295 919.0
WH2_k127_9139122_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000006823 175.0
WH2_k127_9144065_0 - - - - 5.63e-236 742.0
WH2_k127_9144065_1 Protein of unknown function (DUF3141) - - - 0.0000000000000000000000000000000000000003898 154.0
WH2_k127_9144775_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 337.0
WH2_k127_9144775_1 - K01992 - - 0.0000000000000000000000000000000000000000000000000000001858 201.0
WH2_k127_9144775_2 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000001716 201.0
WH2_k127_9162810_0 PFAM aminotransferase class I and II K10206,K14261 - 2.6.1.83 3.666e-209 654.0
WH2_k127_9162810_1 PFAM homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 527.0
WH2_k127_9162810_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 511.0
WH2_k127_9162810_3 phosphoserine phosphatase homoserine phosphotransferase bifunctional protein K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000198 278.0
WH2_k127_9162810_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000001027 111.0
WH2_k127_9162810_5 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000001678 107.0
WH2_k127_9162810_6 - - - - 0.00000000002503 63.0
WH2_k127_9191751_0 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 482.0
WH2_k127_9191751_1 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000009434 123.0
WH2_k127_9191751_2 - - - - 0.0000000000000000000003795 101.0
WH2_k127_9200603_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 445.0
WH2_k127_9200603_1 PFAM cytochrome c class III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 413.0
WH2_k127_9200603_2 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000003358 132.0
WH2_k127_9206699_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.022e-296 918.0
WH2_k127_9206699_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000006929 195.0
WH2_k127_9206699_2 Putative regulatory protein - - - 0.000000000000000000000000000000000000000000000000002106 188.0
WH2_k127_9206699_3 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000001608 180.0
WH2_k127_9206699_4 - - - - 0.00000000000000000000000000000000000000000000004387 174.0
WH2_k127_9211028_0 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0 1095.0
WH2_k127_9211028_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 519.0
WH2_k127_9224865_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 9.298e-308 956.0
WH2_k127_9224865_1 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 482.0
WH2_k127_9224865_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000002056 84.0
WH2_k127_9269435_0 PFAM sulfate transporter K03321 - - 2.155e-284 884.0
WH2_k127_9269435_1 Glutamine amidotransferase domain K00764 - 2.4.2.14 2.667e-211 665.0
WH2_k127_9269435_2 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 300.0
WH2_k127_9276190_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 351.0
WH2_k127_9276190_1 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000008241 188.0
WH2_k127_9280540_0 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 560.0
WH2_k127_9280540_1 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000000000006518 213.0
WH2_k127_9303358_0 PFAM iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 340.0
WH2_k127_9303358_1 alcohol dehydrogenase - - - 0.000000000000000000000000005716 115.0
WH2_k127_9312481_0 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 350.0
WH2_k127_9312481_1 PFAM Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001651 255.0
WH2_k127_9312481_2 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000003791 179.0
WH2_k127_9312481_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000005156 171.0
WH2_k127_9326546_0 short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 457.0
WH2_k127_9326546_1 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 301.0
WH2_k127_9326546_2 transcriptional regulators - - - 0.00000000000000000000000000000000005177 135.0
WH2_k127_9326546_3 4 iron, 4 sulfur cluster binding K12527 - 1.97.1.9 0.000000000000000003344 96.0
WH2_k127_9326546_4 amino acid carrier protein K03310 - - 0.000000000000000005023 83.0
WH2_k127_9326546_5 General secretion pathway protein C K02452 - - 0.00000000001828 75.0
WH2_k127_9331312_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.37e-205 645.0
WH2_k127_9331312_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000001068 174.0
WH2_k127_9331312_2 - - - - 0.0000000000000000009024 91.0
WH2_k127_9342136_0 AMMECR1 K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 389.0
WH2_k127_9344778_0 UvrD REP helicase K03657 - 3.6.4.12 2.307e-256 803.0
WH2_k127_9344778_1 Transfers the fatty acyl group on membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 291.0
WH2_k127_9344778_2 Proteobacterial lipase chaperone protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002109 244.0
WH2_k127_9344778_3 - - - - 0.000000003527 61.0
WH2_k127_9354330_0 Nucleoside recognition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 586.0
WH2_k127_9354330_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002426 273.0
WH2_k127_9354330_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000000000000001856 147.0
WH2_k127_9356978_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000001722 207.0
WH2_k127_9356978_1 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.00000000000000000000000000000000000000000000000149 180.0
WH2_k127_9398573_0 PFAM CDP-glycerol poly(glycerophosphate) glycerophosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 398.0
WH2_k127_9398573_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 334.0
WH2_k127_9398573_2 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000003743 136.0
WH2_k127_9401395_0 Belongs to the GSP D family K02280 - - 0.0000000000000000003335 97.0
WH2_k127_9401395_1 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000004853 76.0
WH2_k127_9404563_0 4Fe-4S dicluster domain - - - 1.351e-302 933.0
WH2_k127_9404563_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 360.0
WH2_k127_9404563_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 352.0
WH2_k127_9404563_3 - - - - 0.000000000000000000000000000000000000000000000001834 176.0
WH2_k127_9404563_4 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0000000000002744 69.0
WH2_k127_9435916_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 9.521e-277 865.0
WH2_k127_9435916_1 Protein of unknown function (DUF3467) - - - 0.00000003294 55.0
WH2_k127_9441172_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 338.0
WH2_k127_9444405_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 526.0
WH2_k127_9444405_1 PGAP1-like protein - - - 0.00000000000000000000000000002756 124.0
WH2_k127_950039_0 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 307.0
WH2_k127_950039_1 Transposase zinc-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007191 266.0
WH2_k127_950039_2 Transposase zinc-binding domain - - - 0.00000000000000000000000000000000000000000000000000000003306 201.0
WH2_k127_950039_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000002478 147.0
WH2_k127_9501294_0 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 579.0
WH2_k127_9501294_1 PFAM dihydropteroate synthase DHPS K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 364.0
WH2_k127_9501294_2 - - - - 0.0000000000005176 70.0
WH2_k127_9501294_5 - - - - 0.0009165 42.0
WH2_k127_9502245_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 3.68e-201 636.0
WH2_k127_9502245_1 PFAM Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 341.0
WH2_k127_9502245_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 304.0
WH2_k127_9502245_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000005951 175.0
WH2_k127_9502245_4 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000001896 153.0
WH2_k127_9502245_5 membrane transporter protein K07090 - - 0.000171 44.0
WH2_k127_951848_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.891e-248 773.0
WH2_k127_951848_1 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000003238 128.0
WH2_k127_9520235_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000503 254.0
WH2_k127_9520235_1 - - - - 0.00000000000000000002289 100.0
WH2_k127_9520235_2 Mechanosensitive ion channel - - - 0.00000000000000002086 91.0
WH2_k127_9528348_0 TraE protein K12067 - - 0.00000000000000000000000000000000000000000000000000000000000007849 221.0
WH2_k127_9528348_1 TraL protein - - - 0.000000000000000000009382 94.0
WH2_k127_9528348_2 - - - - 0.00000000000000000002545 95.0
WH2_k127_9528348_3 TraK protein K12066 - - 0.000000000000002276 85.0
WH2_k127_9528348_4 OmpA family - - - 0.000000000004501 71.0
WH2_k127_9556680_0 Protein of unknown function (DUF3373) - - - 7.159e-212 673.0
WH2_k127_9556680_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 590.0
WH2_k127_9556680_10 - - - - 0.00000001164 57.0
WH2_k127_9556680_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 498.0
WH2_k127_9556680_3 - - - - 0.000000000000000000000000000000000000004508 147.0
WH2_k127_9556680_4 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000001911 139.0
WH2_k127_9556680_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000788 128.0
WH2_k127_9556680_6 Molybdopterin oxidoreductase Fe4S4 domain K08352 - 1.8.5.5 0.00000000000000000000000000000003541 128.0
WH2_k127_9556680_7 - - - - 0.00000000000000000000000000002581 121.0
WH2_k127_9556680_8 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000003293 120.0
WH2_k127_9556680_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000004391 111.0
WH2_k127_9560027_0 MMPL family K07003 - - 1.11e-214 682.0
WH2_k127_9560027_1 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000006298 171.0
WH2_k127_9560027_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000008577 120.0
WH2_k127_9564032_0 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 565.0
WH2_k127_9564032_1 Belongs to the FGGY kinase family K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0006066,GO:0006071,GO:0006072,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046167,GO:0046486,GO:0052646,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576,GO:1901615 2.7.1.30 0.00001595 48.0
WH2_k127_9564827_0 CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 481.0
WH2_k127_9564827_1 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 421.0
WH2_k127_9564827_2 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 334.0
WH2_k127_9564827_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 329.0
WH2_k127_9564827_4 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001826 281.0
WH2_k127_9564827_5 NIL - - - 0.00000000000000000000000000000000000000000000000000000003117 199.0
WH2_k127_9564827_6 MerR, DNA binding - - - 0.00000000000000000000000000000000000009536 145.0
WH2_k127_957840_0 Serine dehydratase alpha chain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 457.0
WH2_k127_957840_1 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 301.0
WH2_k127_9631870_0 histone deacetylase - - - 2.271e-220 698.0
WH2_k127_9631870_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 544.0
WH2_k127_9631870_2 FtsJ-like methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000535 256.0
WH2_k127_9631870_3 - - - - 0.000004933 49.0
WH2_k127_9641237_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 392.0
WH2_k127_9641237_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000151 198.0
WH2_k127_9644095_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 518.0
WH2_k127_9644095_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 352.0
WH2_k127_9644095_2 L-2,4-diaminobutyric acid acetyltransferase K06718 - 2.3.1.178 0.000000000000000000000000000000000000000008812 161.0
WH2_k127_9662895_0 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000009246 173.0
WH2_k127_9662895_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000005247 168.0
WH2_k127_9662895_2 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000005309 83.0
WH2_k127_9662895_3 ORF6N domain - - - 0.000000001159 59.0
WH2_k127_9662895_4 - - - - 0.0005579 50.0
WH2_k127_9673959_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 2.369e-268 841.0
WH2_k127_9673959_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 540.0
WH2_k127_9673959_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 454.0
WH2_k127_9673959_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000001387 247.0
WH2_k127_9683066_0 TIGRFAM threonine synthase K01733 - 4.2.3.1 5.901e-240 748.0
WH2_k127_9683066_1 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 313.0
WH2_k127_9683066_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000119 206.0
WH2_k127_9684133_0 Protein of unknown function, DUF255 K06888 - - 0.0 1008.0
WH2_k127_9684133_1 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001032 236.0
WH2_k127_9686688_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 343.0
WH2_k127_9686688_1 MaoC like domain K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000000002687 196.0
WH2_k127_9686688_2 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000008327 193.0
WH2_k127_9686688_3 Putative metal-binding motif - - - 0.0000000000000005789 91.0
WH2_k127_9686688_4 cell wall organization K18197 - 4.2.2.23 0.0000000000349 76.0
WH2_k127_9693041_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 586.0
WH2_k127_9693041_1 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000004188 165.0
WH2_k127_9693041_2 Psort location Cytoplasmic, score - - - 0.00001614 53.0
WH2_k127_9694380_0 PFAM Nucleoside recognition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002969 267.0
WH2_k127_9694380_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K03394 - 2.1.1.130,2.1.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000002884 254.0
WH2_k127_9694380_2 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000009527 130.0
WH2_k127_9694380_3 CbiD K02188 - 2.1.1.195 0.000000000000000000000000000002526 126.0
WH2_k127_9696538_0 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 518.0
WH2_k127_9705159_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 550.0
WH2_k127_9705159_1 Rhodopirellula transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 461.0
WH2_k127_9705159_3 - - - - 0.0002045 45.0
WH2_k127_9713994_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1213.0
WH2_k127_9713994_1 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 4.574e-285 885.0
WH2_k127_9713994_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 549.0
WH2_k127_9713994_3 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 550.0
WH2_k127_9713994_4 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 357.0
WH2_k127_9713994_5 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 290.0
WH2_k127_9713994_6 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000002729 158.0
WH2_k127_9713994_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000007065 164.0
WH2_k127_9713994_8 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000149 137.0
WH2_k127_9729731_0 PFAM Electron transfer flavoprotein alpha K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 464.0
WH2_k127_9729731_1 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 447.0
WH2_k127_9729731_2 4Fe-4S dicluster domain - - - 0.00000000217 58.0
WH2_k127_973329_0 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000005196 220.0
WH2_k127_973329_1 - - - - 0.00000000000000000000000000000000008363 136.0
WH2_k127_973329_2 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000000000000002673 85.0
WH2_k127_9736288_0 DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 5e-324 1006.0
WH2_k127_9736288_1 impB/mucB/samB family K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000003155 212.0
WH2_k127_9792779_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.000000000000000000000000000000000000000000003928 183.0
WH2_k127_9800959_0 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 353.0
WH2_k127_9800959_1 Inner membrane component domain - - - 0.0000000000000000000000000000000000000000000000000000008986 194.0
WH2_k127_9800959_2 Cupin - - - 0.000000000001609 71.0
WH2_k127_9813416_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1070.0
WH2_k127_9813416_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000002319 65.0
WH2_k127_9813416_2 Psort location Cytoplasmic, score 8.87 - - - 0.0007619 44.0
WH2_k127_9821446_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 545.0
WH2_k127_9821446_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 509.0
WH2_k127_9821446_2 TIGRFAM tyrosine recombinase XerD K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 409.0
WH2_k127_9821446_3 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 393.0
WH2_k127_9821446_4 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 291.0
WH2_k127_9821446_5 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000007124 172.0
WH2_k127_9821446_6 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000483 141.0
WH2_k127_9821446_7 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000005247 128.0
WH2_k127_9821446_8 - - - - 0.0000001097 58.0
WH2_k127_9821446_9 Amidohydrolase family K20810 - 3.5.4.40 0.000006736 51.0
WH2_k127_9856327_0 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007021 334.0
WH2_k127_9856327_1 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000008403 190.0
WH2_k127_9856327_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000001831 168.0
WH2_k127_9856327_3 nitrate reductase activity - - - 0.00000000000000000000000000000000000000001267 162.0
WH2_k127_9856327_4 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000009884 83.0
WH2_k127_986000_0 Pyridoxamine 5'-phosphate oxidase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 319.0
WH2_k127_986000_1 Fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 314.0
WH2_k127_986000_2 TIGRFAM phosphodiesterase, MJ0936 family K07095 - - 0.0000000000000000000000000000000000000000000000000002235 191.0
WH2_k127_986000_3 Domain of unknown function (DUF4412) - - - 0.000000000000000000000000000000000000000000001107 176.0
WH2_k127_986000_4 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.0000000000000000000193 93.0
WH2_k127_9890929_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 6.333e-308 949.0
WH2_k127_9890929_1 PFAM molybdopterin oxidoreductase K00336,K05299 - 1.17.1.10,1.6.5.3 8.24e-259 824.0
WH2_k127_9890929_2 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003367 255.0
WH2_k127_9890929_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001906 233.0
WH2_k127_9895425_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.007e-215 674.0
WH2_k127_9895425_1 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000001795 200.0
WH2_k127_9895425_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000001265 196.0
WH2_k127_9895425_3 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000003611 149.0
WH2_k127_9904565_0 Fimbrial assembly family protein K02461 - - 0.000000000000000000000000000000000000000000000000001089 196.0
WH2_k127_9904565_1 Type II secretion system (T2SS), protein M K02462 - - 0.000000000000000000000000000000000000000000001594 170.0
WH2_k127_9904565_2 - - - - 0.00000000001065 71.0
WH2_k127_9909585_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 299.0
WH2_k127_9909585_1 type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007987 279.0
WH2_k127_9909585_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.0000000000000000000000000000000000000000000000008009 180.0
WH2_k127_9910587_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 487.0
WH2_k127_9910587_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 314.0
WH2_k127_9910587_2 O-acyltransferase activity K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000002722 219.0
WH2_k127_9910587_3 Acetyltransferase (GNAT) domain - - - 0.00000001204 62.0
WH2_k127_9916494_0 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 468.0
WH2_k127_9916494_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 426.0
WH2_k127_9916494_2 VWA containing CoxE family protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 364.0
WH2_k127_9916494_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000008876 179.0
WH2_k127_9916494_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000007603 85.0
WH2_k127_9917609_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 440.0
WH2_k127_9917609_1 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 305.0
WH2_k127_9917609_2 Rhomboid family - - - 0.000000000000000000000000000000000000000000001678 173.0
WH2_k127_9968694_0 General secretory system II protein E domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 612.0
WH2_k127_9968694_1 PFAM ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 576.0
WH2_k127_9968694_2 - - - - 0.00000000000003306 78.0
WH2_k127_9975351_0 Protein of unknown function (DUF3999) - - - 0.000000000000000000000000000000000000000000000000000002856 206.0
WH2_k127_9975351_1 - - - - 0.00000000000000000000000000000000000000000005894 164.0