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Overview

ID MAG04122
Name WH2_bin.33
Sample SMP0107
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Sphingomonadales
Family Sphingomonadaceae
Genus Erythrobacter
Species
Assembly information
Completeness (%) 68.17
Contamination (%) 2.02
GC content (%) 65.0
N50 (bp) 4,835
Genome size (bp) 1,972,921

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2193

Gene name Description KEGG GOs EC E-value Score Sequence
WH2_k127_10007328_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.442e-247 768.0
WH2_k127_10007328_1 Glycosyl hydrolases family 25 K07273 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 341.0
WH2_k127_10007328_2 Belongs to the UPF0262 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 335.0
WH2_k127_10030632_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 3.987e-211 665.0
WH2_k127_10030632_1 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 550.0
WH2_k127_10030632_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 462.0
WH2_k127_10030632_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000000000000000000007285 218.0
WH2_k127_10030632_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000002413 160.0
WH2_k127_10043751_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1314.0
WH2_k127_10045356_0 cytochrome c biogenesis K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 468.0
WH2_k127_10045356_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 367.0
WH2_k127_10045356_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000004462 201.0
WH2_k127_10048197_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 598.0
WH2_k127_10048197_1 Prolyl oligopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 357.0
WH2_k127_10053190_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 7.202e-258 796.0
WH2_k127_10053190_1 Protein of unknown function (DUF2855) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 419.0
WH2_k127_1007337_0 Outer membrane receptor - - - 6.826e-244 774.0
WH2_k127_1007337_1 Fe2 -dicitrate sensor, membrane component K07165 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001978 252.0
WH2_k127_1007337_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000001314 141.0
WH2_k127_10085932_0 Toxic anion resistance - - - 2.412e-227 708.0
WH2_k127_10085932_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 388.0
WH2_k127_10085932_2 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.000000000000000000000000000000000000000000000003519 173.0
WH2_k127_10085932_4 Domain of unknown function (DUF389) - - - 0.00000000000000000000001431 106.0
WH2_k127_10098152_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1064.0
WH2_k127_10113264_0 TonB-dependent receptor - - - 2.217e-293 909.0
WH2_k127_10113264_1 Ring hydroxylating alpha subunit (catalytic domain) - - - 2.749e-273 846.0
WH2_k127_10113264_2 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 561.0
WH2_k127_10113264_3 Enoyl-(Acyl carrier protein) reductase K05296 - 1.1.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 481.0
WH2_k127_10119445_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 563.0
WH2_k127_10119445_1 COG1305 Transglutaminase-like enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009223 494.0
WH2_k127_10119445_2 proteasome-type protease K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 452.0
WH2_k127_10119445_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 390.0
WH2_k127_10123780_0 Histidine kinase - - - 2.93e-223 697.0
WH2_k127_10123780_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 443.0
WH2_k127_10123780_2 Response regulator of the LytR AlgR family K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 416.0
WH2_k127_10123780_4 - - - - 0.0000000000000000001496 95.0
WH2_k127_10145650_0 Histidine kinase - - - 7.723e-310 955.0
WH2_k127_10145650_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 7.004e-293 902.0
WH2_k127_10145650_2 Alkyl hydroperoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 304.0
WH2_k127_10145650_3 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000009429 208.0
WH2_k127_10145650_4 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000003699 164.0
WH2_k127_10145650_5 Cytochrome C' - - - 0.00000000009308 61.0
WH2_k127_10202027_0 Transcriptional regulator K02529 - - 5.886e-202 632.0
WH2_k127_10202027_1 Belongs to the glycosyl hydrolase 31 family K15922 - 3.2.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 572.0
WH2_k127_10202027_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 548.0
WH2_k127_10202027_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000003678 218.0
WH2_k127_10202327_0 coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 537.0
WH2_k127_10202327_1 ICC-like phosphoesterases K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 436.0
WH2_k127_10202327_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 316.0
WH2_k127_10202327_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000004881 258.0
WH2_k127_10257303_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 3.368e-271 842.0
WH2_k127_10257303_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 6.187e-243 753.0
WH2_k127_10257303_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 416.0
WH2_k127_10257303_3 Protein of unknown function (DUF418) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 310.0
WH2_k127_10257303_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002679 271.0
WH2_k127_10257303_5 Domain of unknown function (DUF4167) - - - 0.00000000000000000000000000000000000000000000000000000001384 207.0
WH2_k127_10259584_0 Glycosyl hydrolase family 3 C-terminal domain - - - 0.0 1262.0
WH2_k127_10259584_1 helix_turn _helix lactose operon repressor - - - 6.728e-196 617.0
WH2_k127_10259584_2 Major Facilitator Superfamily - - - 1.252e-195 617.0
WH2_k127_10259584_3 Glycosyl hydrolases family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 574.0
WH2_k127_10259584_4 receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 313.0
WH2_k127_10259584_5 protein conserved in bacteria - - - 0.000000005053 57.0
WH2_k127_10313979_0 acetyl-coa acetyltransferase K00626 - 2.3.1.9 4.999e-293 905.0
WH2_k127_10313979_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 2.4e-213 679.0
WH2_k127_10313979_2 Belongs to the thiolase family K00626 - 2.3.1.9 2.89e-211 670.0
WH2_k127_10313979_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 470.0
WH2_k127_10320324_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1239.0
WH2_k127_10320324_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 1.642e-306 942.0
WH2_k127_10320324_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 566.0
WH2_k127_10320324_3 Haloacid dehalogenase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 387.0
WH2_k127_1034091_0 Outer membrane efflux protein - - - 1.333e-237 743.0
WH2_k127_1034091_1 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 581.0
WH2_k127_1034091_2 ABC transporter, ATP-binding protein K02021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 532.0
WH2_k127_1034091_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 444.0
WH2_k127_1034091_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 306.0
WH2_k127_1034091_5 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000008409 68.0
WH2_k127_10368049_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1064.0
WH2_k127_10368049_1 peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 2.364e-295 918.0
WH2_k127_10368049_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 451.0
WH2_k127_10368049_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 434.0
WH2_k127_10368049_4 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 298.0
WH2_k127_10368049_5 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000001769 218.0
WH2_k127_10368049_6 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000000000000000000000000005864 155.0
WH2_k127_10368049_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000000003554 149.0
WH2_k127_10376650_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 4.267e-245 761.0
WH2_k127_10376650_1 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 315.0
WH2_k127_10376650_2 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000000000000000002254 219.0
WH2_k127_10376650_4 lyase activity - - - 0.00002705 49.0
WH2_k127_10448818_0 ABC transporter permease K05845,K05846 - - 3.303e-279 870.0
WH2_k127_10448818_1 Putative S-adenosyl-L-methionine-dependent methyltransferase K18164 - - 2.608e-216 679.0
WH2_k127_10448818_2 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 342.0
WH2_k127_10448818_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000533 207.0
WH2_k127_10454614_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 1.138e-214 670.0
WH2_k127_10454614_1 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 428.0
WH2_k127_10454614_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 389.0
WH2_k127_10454614_3 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004457 260.0
WH2_k127_10478654_0 Flotillin - - - 8.46e-292 904.0
WH2_k127_10478654_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 531.0
WH2_k127_10478654_2 Protein of unknown function (DUF1449) - - - 0.00000000000000000000000000000000000000000000000000178 183.0
WH2_k127_10490591_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 2.323e-303 966.0
WH2_k127_10490591_1 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 385.0
WH2_k127_10490591_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008042 264.0
WH2_k127_10490591_3 Belongs to the Nudix hydrolase family K03426 - 3.6.1.22 0.000000000000000000000000832 103.0
WH2_k127_10494386_0 Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine K01761 - 4.4.1.11 1.515e-267 826.0
WH2_k127_10494386_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 527.0
WH2_k127_10494386_2 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 342.0
WH2_k127_10494386_3 molecular chaperone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 327.0
WH2_k127_10494386_4 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002036 266.0
WH2_k127_10499264_0 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.492e-289 897.0
WH2_k127_10499264_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 599.0
WH2_k127_10499264_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002474 254.0
WH2_k127_10499266_0 acyl-CoA dehydrogenase K20035 - - 1.352e-282 871.0
WH2_k127_10499266_1 ATPase (AAA superfamily) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000295 278.0
WH2_k127_1050659_0 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 602.0
WH2_k127_1050659_1 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 411.0
WH2_k127_1050659_2 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.00000000000000000000000000000000000000000001358 164.0
WH2_k127_10508280_0 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 404.0
WH2_k127_10508280_1 thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 298.0
WH2_k127_10508280_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008393 247.0
WH2_k127_10508280_3 Biopolymer transport protein K03560 - - 0.0000000000000000000000000000000000000000000000000000000000000002821 224.0
WH2_k127_10508280_4 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.00000000000000000000000000000000000000000001382 166.0
WH2_k127_10508280_5 membrane - - - 0.000000000000000000000000000001307 123.0
WH2_k127_10508280_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000002876 93.0
WH2_k127_10511234_0 chromate transporter K07240 - - 2.887e-207 651.0
WH2_k127_10511234_1 Mo-co oxidoreductase dimerisation domain - - - 7.638e-205 642.0
WH2_k127_10511234_2 Cytochrome c - - - 0.00000000000000000000000000000000000003717 146.0
WH2_k127_10511234_3 3,4-dihydroxy-2-butanone 4-phosphate synthase - - - 0.00002287 46.0
WH2_k127_10535905_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0 1000.0
WH2_k127_10535905_1 beta-N-acetylhexosaminidase K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 603.0
WH2_k127_10535905_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 467.0
WH2_k127_10535905_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 348.0
WH2_k127_10535905_4 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 326.0
WH2_k127_10535905_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000000000001886 123.0
WH2_k127_10535905_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000001363 88.0
WH2_k127_1055171_0 aminopeptidase K01262 - 3.4.11.9 1.769e-238 741.0
WH2_k127_1055171_1 peptidase S9 K01354 - 3.4.21.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 559.0
WH2_k127_10575231_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 335.0
WH2_k127_10575231_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 290.0
WH2_k127_10575231_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001954 274.0
WH2_k127_10575231_3 - - - - 0.000000000000000000000000000007886 122.0
WH2_k127_10575231_4 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000002261 74.0
WH2_k127_10577236_0 Prolyl oligopeptidase - - - 6.092e-239 746.0
WH2_k127_10577236_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 436.0
WH2_k127_10577236_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 396.0
WH2_k127_10577236_3 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 336.0
WH2_k127_10577236_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 301.0
WH2_k127_10577236_5 chorismate mutase K04782 - 4.2.99.21 0.0000000000000000000000000000000000000000000001837 171.0
WH2_k127_10577236_6 - - - - 0.00000002891 54.0
WH2_k127_10577474_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 2.976e-296 910.0
WH2_k127_10577474_1 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 396.0
WH2_k127_10577474_2 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 358.0
WH2_k127_10580627_0 Histidine kinase K13587 - 2.7.13.3 0.0 1368.0
WH2_k127_10580627_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004151 262.0
WH2_k127_10581158_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 1.849e-230 716.0
WH2_k127_10581158_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 490.0
WH2_k127_10605436_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 6.954e-306 938.0
WH2_k127_10605436_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 535.0
WH2_k127_10605436_2 acetolactate synthase K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 325.0
WH2_k127_10627978_0 Ring hydroxylating alpha subunit (catalytic domain) - - - 4.939e-227 711.0
WH2_k127_10627978_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 504.0
WH2_k127_10627978_2 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000001665 217.0
WH2_k127_10627978_3 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000008072 168.0
WH2_k127_10655210_0 COG0729 Outer membrane protein K07278 - - 0.0 1099.0
WH2_k127_10655210_1 protein conserved in bacteria K09800 - - 1.039e-303 940.0
WH2_k127_10655210_2 Threonine dehydratase K01754 - 4.3.1.19 4.044e-196 612.0
WH2_k127_10655210_3 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 527.0
WH2_k127_10684530_0 molecular chaperone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 557.0
WH2_k127_10684530_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 450.0
WH2_k127_10684530_2 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 409.0
WH2_k127_10687784_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.259e-276 852.0
WH2_k127_10687784_1 COG1226 Kef-type K transport systems K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 601.0
WH2_k127_10687784_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 370.0
WH2_k127_10687784_3 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 319.0
WH2_k127_10687784_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007931 248.0
WH2_k127_10687784_5 Protein of unknown function (DUF1761) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001839 240.0
WH2_k127_10687784_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000001821 212.0
WH2_k127_10687784_7 - - - - 0.000000000000000000000000000000000000001399 149.0
WH2_k127_10698004_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1153.0
WH2_k127_10698004_1 Peptidase, M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 370.0
WH2_k127_10699507_0 Belongs to the ClpA ClpB family K03694 - - 1.859e-311 956.0
WH2_k127_10699507_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000251 216.0
WH2_k127_10714651_0 Copper-binding protein - - - 5.792e-317 976.0
WH2_k127_10714651_1 amidohydrolase - - - 9.016e-233 725.0
WH2_k127_10714651_2 amidohydrolase - - - 5.031e-205 646.0
WH2_k127_10714651_3 LacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 519.0
WH2_k127_10727604_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 5.105e-235 731.0
WH2_k127_10727604_1 Steryl acetyl hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 534.0
WH2_k127_10727604_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 369.0
WH2_k127_10727604_3 Thioredoxin-like - - - 0.000000000000000000000000000003225 123.0
WH2_k127_1083852_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1633.0
WH2_k127_1083852_1 Acetoacetyl-CoA reductase K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 460.0
WH2_k127_1083852_2 Belongs to the RNase T2 family K01166 - 3.1.27.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 414.0
WH2_k127_1083852_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 373.0
WH2_k127_1083852_4 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 303.0
WH2_k127_1083852_5 Domain of unknown function (DUF3576) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007899 251.0
WH2_k127_1083852_6 protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis - - - 0.000000000000000000000000000000001043 131.0
WH2_k127_1083852_7 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000005473 120.0
WH2_k127_1083852_8 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000001949 72.0
WH2_k127_1083852_9 Lipopolysaccharide-assembly K03643 - - 0.0000004588 55.0
WH2_k127_1091408_0 nuclear chromosome segregation - - - 1.323e-288 896.0
WH2_k127_1091408_1 metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000001775 192.0
WH2_k127_1091408_2 Protein of unknown function (DUF1467) - - - 0.000000000000000000000000000000000000000000005464 164.0
WH2_k127_1103310_0 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 556.0
WH2_k127_1103310_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 316.0
WH2_k127_1103310_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 300.0
WH2_k127_1103310_3 MerC mercury resistance protein - - - 0.0000000000000000000000000000000000000000000000000000008269 194.0
WH2_k127_1103310_5 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000000000007525 152.0
WH2_k127_1103310_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000002572 88.0
WH2_k127_1116966_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 523.0
WH2_k127_1116966_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 512.0
WH2_k127_1116966_2 ABC transporter, ATP-binding protein K02021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 389.0
WH2_k127_1133335_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0 1592.0
WH2_k127_1133335_1 Alpha-amylase domain K01187 - 3.2.1.20 4.838e-305 939.0
WH2_k127_1133335_2 Tryptophan halogenase - - - 5.111e-295 912.0
WH2_k127_1133335_3 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 605.0
WH2_k127_1139115_0 Heparinase - - - 0.0 1080.0
WH2_k127_1139115_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.048e-303 938.0
WH2_k127_1139115_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 413.0
WH2_k127_1139115_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 385.0
WH2_k127_1139115_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000001045 151.0
WH2_k127_1171190_0 DNA polymerase K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 488.0
WH2_k127_1171190_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 374.0
WH2_k127_1171190_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009287 302.0
WH2_k127_1171190_3 - - - - 0.000000000000000000000000002673 113.0
WH2_k127_1171190_4 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.000003319 56.0
WH2_k127_1179871_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.079e-286 881.0
WH2_k127_1179871_1 Phosphotransferase enzyme family - - - 2.829e-215 676.0
WH2_k127_1179871_2 Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 518.0
WH2_k127_1179871_3 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 409.0
WH2_k127_1179871_4 Periplasmic component of the Tol biopolymer transport system - - - 0.000007783 52.0
WH2_k127_1217160_0 Nitrogenase component 1 type Oxidoreductase K11334 - 1.3.7.14,1.3.7.15 1.199e-234 727.0
WH2_k127_1217160_1 Proto-chlorophyllide reductase 57 kD subunit K11335 - 1.3.7.14,1.3.7.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 436.0
WH2_k127_1256186_0 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) K01484 - 3.5.3.23 2.425e-212 661.0
WH2_k127_1256186_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 520.0
WH2_k127_1256186_2 arginine N-succinyltransferase K00673 - 2.3.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 434.0
WH2_k127_1262346_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 2.278e-194 608.0
WH2_k127_1262346_1 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 538.0
WH2_k127_1262346_2 Oxidoreductase K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 513.0
WH2_k127_1262346_3 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 379.0
WH2_k127_1262346_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 351.0
WH2_k127_1262346_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000006427 244.0
WH2_k127_1262346_6 Domain of unknown function (DUF1508) K09946 - - 0.000000000000000000000000006404 112.0
WH2_k127_1262431_0 LVIVD repeat - - - 0.0 1318.0
WH2_k127_1262431_1 - - - - 8.308e-301 923.0
WH2_k127_1270255_0 sugar transferase K20997 - - 1.983e-254 789.0
WH2_k127_1270255_1 DNA polymerase III K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 586.0
WH2_k127_1270255_2 Lipopolysaccharide-assembly K03643 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000332 243.0
WH2_k127_1283770_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.0 1405.0
WH2_k127_1283770_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 622.0
WH2_k127_1283770_2 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 461.0
WH2_k127_1283770_3 - - - - 0.00000000001054 78.0
WH2_k127_1297547_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.268e-319 980.0
WH2_k127_1297547_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 3.53e-263 814.0
WH2_k127_1297547_2 amidohydrolase - - - 2.166e-208 650.0
WH2_k127_1297547_3 2-nitropropane dioxygenase K00459 - 1.13.12.16 3.089e-204 637.0
WH2_k127_1297547_4 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 424.0
WH2_k127_1297547_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 378.0
WH2_k127_1297547_6 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002895 273.0
WH2_k127_1297547_7 COG0655 Multimeric flavodoxin WrbA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000865 255.0
WH2_k127_1312196_0 DNA mediated transformation - - - 0.0 1004.0
WH2_k127_1312196_1 TIR domain - - - 1.188e-314 974.0
WH2_k127_1312196_2 Proton-conducting membrane transporter K05561 - - 2.727e-236 739.0
WH2_k127_1312196_3 Domain related to MnhB subunit of Na+/H+ antiporter K05559 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 567.0
WH2_k127_1312196_4 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 553.0
WH2_k127_1312196_5 Na+/H+ ion antiporter subunit K05562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009735 265.0
WH2_k127_1312196_6 Na+/H+ antiporter subunit K05564 - - 0.000000000000000000000000000000000000000000000000000000000008761 214.0
WH2_k127_1312196_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560 - - 0.00000000000000000000000000000000000000000000000000001063 196.0
WH2_k127_1312196_9 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05563 - - 0.0000000000000000000000000000000005958 139.0
WH2_k127_1345781_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0 1032.0
WH2_k127_1345781_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 9.822e-248 768.0
WH2_k127_1345781_2 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 513.0
WH2_k127_1345781_3 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 502.0
WH2_k127_1345781_4 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 374.0
WH2_k127_1345781_5 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 304.0
WH2_k127_1345781_6 Bacteriochlorophyll 4-vinyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000002162 212.0
WH2_k127_1345781_7 - - - - 0.000000000000000000000001205 105.0
WH2_k127_1346223_0 amino acid K03294 - - 1.048e-271 843.0
WH2_k127_1346223_1 SOS response K14160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 322.0
WH2_k127_1346223_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000001959 248.0
WH2_k127_1396760_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 532.0
WH2_k127_1396760_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01502 - 3.5.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 459.0
WH2_k127_1396760_2 phenylacetate-CoA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 289.0
WH2_k127_1396760_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 288.0
WH2_k127_1396760_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004168 285.0
WH2_k127_1396760_5 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001444 254.0
WH2_k127_1400457_0 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 3.675e-245 770.0
WH2_k127_1400457_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.933e-239 741.0
WH2_k127_1400457_2 Metal binding domain of Ada K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 559.0
WH2_k127_1400457_3 dioxygenase K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 524.0
WH2_k127_1400457_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 293.0
WH2_k127_1400457_5 - - - - 0.000000000000000000000000000000003985 136.0
WH2_k127_1401929_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0 1163.0
WH2_k127_1401929_1 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009065 266.0
WH2_k127_1401929_2 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000399 219.0
WH2_k127_1537535_0 glycosyl transferase group 1 - - - 7.896e-215 670.0
WH2_k127_1537535_1 NADPH quinone - - - 3.861e-198 619.0
WH2_k127_1537535_2 Belongs to the ClpA ClpB family K03694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 603.0
WH2_k127_1537535_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 602.0
WH2_k127_1537535_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 593.0
WH2_k127_1537535_5 protein conserved in bacteria K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 449.0
WH2_k127_1537535_6 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 302.0
WH2_k127_1537535_7 Protein of unknown function (DUF1192) - - - 0.00000000000000000000000000003067 119.0
WH2_k127_1550193_0 Phage shock protein A K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 507.0
WH2_k127_1550193_1 PspC domain K03973 - - 0.00000000000000000000000000000000000000000000000000000000000000000001297 235.0
WH2_k127_1550193_2 Phage shock protein B K03970 - - 0.00000000000000000000000000000000000000000005629 161.0
WH2_k127_1550193_3 - - - - 0.000000000000000000000000000000000000000001119 158.0
WH2_k127_1550193_4 - - - - 0.0000000000000000000000000000000001718 133.0
WH2_k127_1570761_0 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 501.0
WH2_k127_1570761_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 431.0
WH2_k127_1570761_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 423.0
WH2_k127_1570761_3 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 395.0
WH2_k127_1570761_4 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 302.0
WH2_k127_157369_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 8.967e-235 729.0
WH2_k127_157369_1 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 1.522e-226 709.0
WH2_k127_157369_2 COG0463 Glycosyltransferases involved in cell wall biogenesis K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000004796 256.0
WH2_k127_157369_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 244.0
WH2_k127_157369_4 - - - - 0.0000000000000000000000000000000000000000007642 161.0
WH2_k127_1598231_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 7.874e-287 882.0
WH2_k127_1598231_1 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 2.701e-212 662.0
WH2_k127_1598844_0 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 2.5e-249 775.0
WH2_k127_1598844_1 - - - - 9.329e-199 627.0
WH2_k127_1598844_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 591.0
WH2_k127_1598844_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 585.0
WH2_k127_1598844_4 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 480.0
WH2_k127_1598844_5 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 462.0
WH2_k127_1598844_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 355.0
WH2_k127_1598844_7 cytochrome C K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 343.0
WH2_k127_1607583_0 DNA polymerase K02337 - 2.7.7.7 0.0 1251.0
WH2_k127_1620207_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 8.065e-266 819.0
WH2_k127_1620207_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 410.0
WH2_k127_1620207_2 Predicted membrane protein (DUF2177) - - - 0.000000000000000000000000000000000000001001 148.0
WH2_k127_1641191_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0 1595.0
WH2_k127_1641191_1 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 2.631e-301 929.0
WH2_k127_1641191_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 2.394e-198 621.0
WH2_k127_1641191_3 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 469.0
WH2_k127_1641191_4 ubiE/COQ5 methyltransferase family K13623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 281.0
WH2_k127_1641191_5 MAPEG family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003608 267.0
WH2_k127_1641191_6 MAPEG family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008786 245.0
WH2_k127_1641191_7 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006971 233.0
WH2_k127_165278_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 7.47e-318 976.0
WH2_k127_165278_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000003769 234.0
WH2_k127_165278_2 Thioesterase superfamily - - - 0.0000000006665 59.0
WH2_k127_1657472_0 Ring hydroxylating alpha subunit (catalytic domain) - - - 2.619e-221 693.0
WH2_k127_1657472_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 454.0
WH2_k127_1657472_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 399.0
WH2_k127_1657472_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 394.0
WH2_k127_1657472_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 384.0
WH2_k127_1657472_5 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 332.0
WH2_k127_1657472_6 protein conserved in bacteria K09985 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 291.0
WH2_k127_1657472_7 - - - - 0.00000000000000000000000000000000007114 138.0
WH2_k127_1657472_8 YCII-related domain - - - 0.000000000000000000000001541 108.0
WH2_k127_1657472_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0001651 44.0
WH2_k127_1658933_0 cystathionine beta-lyase K01760 - 4.4.1.8 6.607e-221 694.0
WH2_k127_1658933_1 Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 396.0
WH2_k127_1658933_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005297 269.0
WH2_k127_1658933_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000005723 161.0
WH2_k127_1658933_4 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.00002618 48.0
WH2_k127_1663336_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.534e-260 804.0
WH2_k127_1663336_1 synthase K00574 - 2.1.1.79 1.084e-237 742.0
WH2_k127_1663336_2 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 443.0
WH2_k127_1663336_3 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000000000000183 225.0
WH2_k127_1710359_0 cytochrome C K02198 - - 0.0 1026.0
WH2_k127_1710359_1 Alkyl hydroperoxide reductase K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 329.0
WH2_k127_1710359_2 subunit of a heme lyase K02200 - - 0.0000000000000000000006496 96.0
WH2_k127_1713887_0 sulfate adenylyltransferase K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 558.0
WH2_k127_1713887_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 346.0
WH2_k127_1713887_2 L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 318.0
WH2_k127_1720396_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 6.475e-212 660.0
WH2_k127_1720396_1 COG0659 Sulfate permease and related transporters (MFS superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 340.0
WH2_k127_1720743_0 TonB dependent receptor - - - 0.0 1155.0
WH2_k127_1720743_1 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 540.0
WH2_k127_1720743_2 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 507.0
WH2_k127_1720743_4 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 420.0
WH2_k127_1720743_5 GDYXXLXY protein - - - 0.00000000000000000000000000000000000000000000000000000000000001362 224.0
WH2_k127_1727593_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 396.0
WH2_k127_1727593_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
WH2_k127_1727593_2 Belongs to the Fur family K09823 - - 0.0000000000000000000000000000000000000000000000002244 176.0
WH2_k127_1760817_0 Heat shock 70 kDa protein K04043 - - 0.0 1139.0
WH2_k127_1760817_1 Protein of unknown function (DUF3376) - - - 0.0 1016.0
WH2_k127_1760817_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 7.141e-220 685.0
WH2_k127_1760817_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 389.0
WH2_k127_1760817_4 Pfam:DUF461 K09796 - - 0.00000000000000000000000000000000000000000000000000000000000000000787 232.0
WH2_k127_1760817_5 - - - - 0.0000000000000000000000003058 106.0
WH2_k127_1768699_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 439.0
WH2_k127_1768699_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000005847 244.0
WH2_k127_1768699_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000007668 76.0
WH2_k127_1892982_0 Glycogen debranching enzyme, glucanotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 536.0
WH2_k127_1892982_1 COG0477 Permeases of the major facilitator superfamily K16211 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 434.0
WH2_k127_1904324_0 RpsU-divergently transcribed K18587 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 394.0
WH2_k127_1904324_1 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 333.0
WH2_k127_1904324_2 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 330.0
WH2_k127_1904324_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000176 267.0
WH2_k127_1912095_0 - - - - 5.432e-199 623.0
WH2_k127_1912095_1 Ecdysteroid kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 561.0
WH2_k127_1912095_2 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 404.0
WH2_k127_1912095_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000000000000004505 217.0
WH2_k127_1912095_4 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000001134 206.0
WH2_k127_1912095_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000000000000001254 135.0
WH2_k127_1942194_0 hydroxyneurosporene synthase K09844 - 4.2.1.131 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 482.0
WH2_k127_1942194_1 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 290.0
WH2_k127_1942194_2 Alpha/beta hydrolase family K06049 - - 0.0000000000000000000000000000000001313 133.0
WH2_k127_1942194_4 Flavin containing amine oxidoreductase K09845 - 1.3.99.27 0.00000000004777 63.0
WH2_k127_1955_0 5-aminolevulinic acid synthase - - - 1.836e-263 814.0
WH2_k127_1955_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K04035 - 1.14.13.81 1.192e-211 666.0
WH2_k127_1955_2 Photosynthetic reaction centre, H-chain N-terminal region K13991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 501.0
WH2_k127_1955_3 Protein of unknown function (DUF3623) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 438.0
WH2_k127_1955_4 Bacterial PH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 377.0
WH2_k127_1955_5 Photosynthetic complex assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001191 256.0
WH2_k127_1955_6 - - - - 0.0000000000000000000000000000000000000000000003593 169.0
WH2_k127_1962753_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1430.0
WH2_k127_1962753_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000008722 205.0
WH2_k127_1962753_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000000000000007369 201.0
WH2_k127_1962753_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000000000001993 165.0
WH2_k127_1971723_0 Alkaline phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 603.0
WH2_k127_1971723_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 430.0
WH2_k127_1971723_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 309.0
WH2_k127_2004605_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 461.0
WH2_k127_2004605_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 311.0
WH2_k127_2004605_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000385 271.0
WH2_k127_2004605_3 cytochrome C K02198 - - 0.00000000000000000000000006648 109.0
WH2_k127_201262_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0 1397.0
WH2_k127_201262_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 539.0
WH2_k127_201262_2 Protein of unknown function (DUF1465) K13592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000134 279.0
WH2_k127_201262_3 Protein of unknown function (DUF465) - - - 0.000000000000000000000000001433 113.0
WH2_k127_201262_4 Protein of unknown function (DUF465) - - - 0.0000000000000000577 82.0
WH2_k127_2059141_0 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 483.0
WH2_k127_2059141_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 378.0
WH2_k127_2059141_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 332.0
WH2_k127_2059141_3 N-carbamoylputrescine amidase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 324.0
WH2_k127_206830_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 1.514e-205 645.0
WH2_k127_206830_1 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 561.0
WH2_k127_206830_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 468.0
WH2_k127_206830_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006149 279.0
WH2_k127_209121_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1402.0
WH2_k127_209121_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 2.852e-201 631.0
WH2_k127_209121_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 578.0
WH2_k127_209121_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000006918 230.0
WH2_k127_209121_4 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000001845 228.0
WH2_k127_209121_5 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.00000000000000000000000000000000000000000000000000000000001203 211.0
WH2_k127_209121_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000000004581 191.0
WH2_k127_209121_7 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000006692 115.0
WH2_k127_209266_0 receptor - - - 0.0 1184.0
WH2_k127_209266_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.809e-232 721.0
WH2_k127_2095272_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 3.894e-263 812.0
WH2_k127_2095272_1 Belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 586.0
WH2_k127_2095272_2 ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 524.0
WH2_k127_2095272_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 417.0
WH2_k127_2095272_4 Belongs to the CinA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009685 244.0
WH2_k127_2095272_5 succinate dehydrogenase K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000001639 222.0
WH2_k127_2095272_6 succinate dehydrogenase K00242 - - 0.00000000000000000000000000000000000000000000000000000000000000109 220.0
WH2_k127_2095272_7 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000001814 213.0
WH2_k127_2095272_8 GIY-YIG catalytic domain - - - 0.0000000000000000000000000000000000000000007627 158.0
WH2_k127_2111285_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 529.0
WH2_k127_2111285_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 497.0
WH2_k127_2111285_2 hydrolase of the alpha beta superfamily K07017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 308.0
WH2_k127_2138215_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002412 262.0
WH2_k127_2138215_1 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001008 259.0
WH2_k127_2138215_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001793 258.0
WH2_k127_2153535_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 6.736e-274 846.0
WH2_k127_2153535_1 Peptidase dimerisation domain - - - 2.914e-265 823.0
WH2_k127_2153535_2 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 315.0
WH2_k127_2179038_0 Response regulator of the LytR AlgR family K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 511.0
WH2_k127_2179038_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002829 263.0
WH2_k127_2179038_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000004962 248.0
WH2_k127_2244315_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.867e-244 754.0
WH2_k127_2244315_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.331e-198 619.0
WH2_k127_2244315_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 424.0
WH2_k127_2244315_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 375.0
WH2_k127_2244315_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002996 280.0
WH2_k127_2244315_5 bleomycin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001761 228.0
WH2_k127_2244315_6 Lipopolysaccharide assembly protein A domain K08992 - - 0.0000000000000000000000000000000000000000000000001616 179.0
WH2_k127_2334496_0 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 9.883e-206 643.0
WH2_k127_2334496_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 312.0
WH2_k127_2334496_2 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 300.0
WH2_k127_2334496_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 285.0
WH2_k127_2334496_4 Histidine kinase K13587 - 2.7.13.3 0.000000000000000002529 89.0
WH2_k127_2372675_0 Cupin superfamily protein K18850 - 1.14.11.47 8.175e-198 623.0
WH2_k127_2372675_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 488.0
WH2_k127_2372675_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 341.0
WH2_k127_2372675_3 - - - - 0.00000000000000000000000000000001087 130.0
WH2_k127_2372675_4 CcdB protein K19163 - - 0.0000000000000000000000001385 109.0
WH2_k127_2372675_5 Post-segregation antitoxin CcdA K19164 - - 0.0000000000001883 74.0
WH2_k127_240940_0 peptidase S9 - - - 7.529e-307 948.0
WH2_k127_240940_1 membrane K12340 - - 8.903e-253 789.0
WH2_k127_240940_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.226e-238 741.0
WH2_k127_240940_3 Protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 299.0
WH2_k127_240940_4 Protein of unknown function (DUF2497) K09991 - - 0.0000000000000000000000000000000000000000000000000000000000000000008443 231.0
WH2_k127_241831_0 Major Facilitator Superfamily - - - 1.069e-240 750.0
WH2_k127_241831_1 NADH flavin - - - 3.216e-233 723.0
WH2_k127_241831_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 518.0
WH2_k127_241831_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 423.0
WH2_k127_241831_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 400.0
WH2_k127_241831_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 385.0
WH2_k127_241831_6 arsenate reductase K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000002962 213.0
WH2_k127_241831_8 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000001958 66.0
WH2_k127_2433446_0 TonB dependent receptor - - - 4.84e-304 937.0
WH2_k127_2433446_1 CoA-transferase family III - - - 3.451e-229 712.0
WH2_k127_2433446_2 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 605.0
WH2_k127_2433446_3 Citrate synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 480.0
WH2_k127_2433446_4 Chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 437.0
WH2_k127_2433446_5 helix_turn_helix isocitrate lyase regulation K02624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 341.0
WH2_k127_2433446_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000008181 208.0
WH2_k127_2433446_7 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000000387 119.0
WH2_k127_2447999_0 Belongs to the AAA ATPase family K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 554.0
WH2_k127_2447999_1 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 461.0
WH2_k127_2447999_2 - - - - 0.0000001465 53.0
WH2_k127_2485636_0 synthetase K01897 - 6.2.1.3 0.0 1140.0
WH2_k127_2489528_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1035.0
WH2_k127_2489528_1 Alkaline phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002265 248.0
WH2_k127_2489528_2 - - - - 0.00000000000000000000000000000000000000002483 158.0
WH2_k127_2489528_3 Transcriptional regulator K07729 - - 0.000000000000000000000000000004968 119.0
WH2_k127_2505972_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 5.923e-252 781.0
WH2_k127_2505972_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 3.322e-222 695.0
WH2_k127_2505972_10 Belongs to the ArsC family - - - 0.0000000000000000000000000000000000000000000000306 179.0
WH2_k127_2505972_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 565.0
WH2_k127_2505972_3 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 563.0
WH2_k127_2505972_4 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 474.0
WH2_k127_2505972_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 461.0
WH2_k127_2505972_6 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 447.0
WH2_k127_2505972_7 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007062 282.0
WH2_k127_2505972_8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000005016 259.0
WH2_k127_2505972_9 - - - - 0.00000000000000000000000000000000000000000000000006834 180.0
WH2_k127_2545018_0 COG0477 Permeases of the major facilitator superfamily - - - 3.522e-257 800.0
WH2_k127_2545018_1 Copper resistance K07233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 476.0
WH2_k127_2545018_2 MAPEG family - - - 0.00000000000000000000000000000000000000000000000000000245 193.0
WH2_k127_2548903_0 Protein conserved in bacteria - - - 2.018e-267 833.0
WH2_k127_2548903_1 involved in chromosome partitioning - - - 0.000000000000000000000000000000002434 129.0
WH2_k127_2576972_0 amine dehydrogenase activity K01406 - 3.4.24.40 3.047e-282 882.0
WH2_k127_2576972_1 RND efflux system, outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 404.0
WH2_k127_2579800_0 Tryptophan halogenase K14266 - 1.14.19.9 6.447e-202 632.0
WH2_k127_2579800_1 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 397.0
WH2_k127_2579800_2 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 319.0
WH2_k127_2579800_3 Tryptophan halogenase K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000126 278.0
WH2_k127_2579800_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001577 264.0
WH2_k127_2579800_5 Cytochrome c K08738 - - 0.000000000000000000000000000000000000000000000000000000000000004656 230.0
WH2_k127_2586425_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 467.0
WH2_k127_2586425_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 445.0
WH2_k127_2605929_0 Peptidase, M28 - - - 1.487e-247 772.0
WH2_k127_2605929_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 593.0
WH2_k127_2605929_2 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 286.0
WH2_k127_2610523_0 protein conserved in bacteria - - - 6.613e-312 962.0
WH2_k127_2610523_1 Retinal pigment epithelial membrane protein K11159,K21822 - 1.13.11.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 572.0
WH2_k127_2659868_0 Acyl-CoA dehydrogenase, middle domain - - - 8.532e-253 781.0
WH2_k127_2659868_1 COG2211 Na melibiose symporter and related transporters - - - 2.612e-202 640.0
WH2_k127_2659868_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000001226 194.0
WH2_k127_2659868_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000003598 73.0
WH2_k127_2697088_0 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 5.34e-213 664.0
WH2_k127_2697088_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 473.0
WH2_k127_2710571_0 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 2.701e-277 861.0
WH2_k127_2710571_1 SOS response K14160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006648 271.0
WH2_k127_2710571_2 PilZ domain - - - 0.000000000000000000000000000000000000000000003062 171.0
WH2_k127_2710571_3 - - - - 0.00000000000000000000000000000007938 132.0
WH2_k127_2722288_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 573.0
WH2_k127_2722288_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 290.0
WH2_k127_2722288_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 253.0
WH2_k127_2727472_0 Penicillin amidase - - - 0.0 1264.0
WH2_k127_2727472_1 alcohol dehydrogenase K13979 - - 1.32e-221 688.0
WH2_k127_2727472_2 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 455.0
WH2_k127_2727472_3 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 359.0
WH2_k127_2727472_4 YHS domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000249 230.0
WH2_k127_2727472_5 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000118 180.0
WH2_k127_2727472_6 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000001042 155.0
WH2_k127_2727472_7 integral membrane protein - - - 0.0000000000000000000000000000000000001608 143.0
WH2_k127_2747554_0 Trypsin-like serine protease - - - 0.0 1195.0
WH2_k127_2747554_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 289.0
WH2_k127_2751126_0 PAS fold - - - 3.061e-240 752.0
WH2_k127_2773750_0 Allophanate hydrolase subunit 2 K01941 - 6.3.4.6 0.0 1044.0
WH2_k127_2773750_1 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 496.0
WH2_k127_2773750_2 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 449.0
WH2_k127_2773750_3 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 407.0
WH2_k127_2773750_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001577 264.0
WH2_k127_2773750_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000001905 203.0
WH2_k127_2778261_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 531.0
WH2_k127_2778261_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 499.0
WH2_k127_2778261_2 Sulfotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 482.0
WH2_k127_2778261_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 379.0
WH2_k127_2778261_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 283.0
WH2_k127_2778261_5 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000005041 162.0
WH2_k127_2778261_6 UPF0056 membrane protein K05595 - - 0.0000000000000000000000000000000000002352 144.0
WH2_k127_2778261_7 Protein of unknown function (DUF1294) - - - 0.0000000000000000000000000000000007285 133.0
WH2_k127_2778261_8 Protein of unknown function (DUF465) K09794 - - 0.00000000000000000000000000000004846 127.0
WH2_k127_2781954_0 Anticodon-binding domain of tRNA - - - 7.079e-287 887.0
WH2_k127_2781954_1 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 608.0
WH2_k127_2781954_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 473.0
WH2_k127_2788011_0 acyl-CoA dehydrogenase K06446 - - 1.057e-231 721.0
WH2_k127_2788011_1 carnitine dehydratase K14470 - 5.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 512.0
WH2_k127_2788011_3 - - - - 0.000000000000006748 76.0
WH2_k127_280221_0 Autotransporter beta-domain - - - 4.164e-292 908.0
WH2_k127_280221_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 1.715e-204 641.0
WH2_k127_280221_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 436.0
WH2_k127_280221_3 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000002099 218.0
WH2_k127_280221_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000001118 212.0
WH2_k127_280221_5 OmpA-like transmembrane domain K16079 - - 0.00000000000000000000000000000000000000000000000000006619 193.0
WH2_k127_2846187_0 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 559.0
WH2_k127_2846187_1 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000828 519.0
WH2_k127_2846187_2 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 517.0
WH2_k127_2846187_3 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 280.0
WH2_k127_2846187_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000239 261.0
WH2_k127_2846187_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004059 257.0
WH2_k127_2846187_6 Acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000009501 157.0
WH2_k127_2846187_7 Acetyl-coenzyme A transporter 1 - - - 0.00000000000000000000000000000000000000000197 162.0
WH2_k127_2899565_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.685e-306 945.0
WH2_k127_2899565_1 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000003803 90.0
WH2_k127_2901370_0 PFAM Aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 509.0
WH2_k127_2901370_1 conserved protein UCP033924 precursor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 402.0
WH2_k127_2901370_2 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.0002336 46.0
WH2_k127_2924976_0 glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1418.0
WH2_k127_2924976_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 506.0
WH2_k127_2925734_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 2.113e-212 666.0
WH2_k127_2925734_1 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 480.0
WH2_k127_2925734_2 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000001489 186.0
WH2_k127_2925734_3 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.00000000000000000000000000284 114.0
WH2_k127_296905_0 GTP-binding protein TypA K06207 - - 2.083e-277 855.0
WH2_k127_296905_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 3.815e-251 782.0
WH2_k127_296905_2 Extensin-like protein C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 387.0
WH2_k127_296905_3 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001522 234.0
WH2_k127_296905_4 helix_turn_helix, Lux Regulon - - - 0.00000000005508 62.0
WH2_k127_2993823_0 HI0933-like protein K07007 - - 2.812e-230 716.0
WH2_k127_2993823_1 Outer membrane receptor proteins, mostly Fe transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 574.0
WH2_k127_2993823_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000003043 49.0
WH2_k127_3034252_0 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 7.386e-240 747.0
WH2_k127_3034252_1 Domain of unknown function (DUF4403) - - - 1.31e-212 672.0
WH2_k127_3034252_2 conserved secreted or membrane protein precursor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 359.0
WH2_k127_3034252_3 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 363.0
WH2_k127_3034252_4 - - - - 0.00000000000000000003779 92.0
WH2_k127_3034252_5 - - - - 0.00000001171 61.0
WH2_k127_3063966_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1558.0
WH2_k127_3063966_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 544.0
WH2_k127_3063966_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 421.0
WH2_k127_3063966_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 325.0
WH2_k127_3063966_4 phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 295.0
WH2_k127_3063966_6 - - - - 0.00000002049 61.0
WH2_k127_3083455_0 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 550.0
WH2_k127_3083455_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 334.0
WH2_k127_3083455_2 PTS fructose transporter subunit IIA K02793 - 2.7.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000001044 254.0
WH2_k127_3083455_3 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.00000000000000000000000000000000002438 141.0
WH2_k127_3095699_0 Helicase K03722 - 3.6.4.12 0.0 1000.0
WH2_k127_3095699_1 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 329.0
WH2_k127_3095699_2 transcriptional K13639 - - 0.0000000000000000000000000000000000000000000000000345 179.0
WH2_k127_3095699_3 Peptidase family M3 K01284 - 3.4.15.5 0.0001651 44.0
WH2_k127_3137259_0 protein conserved in bacteria - - - 2.415e-292 903.0
WH2_k127_3137259_1 Helix-turn-helix domain - - - 0.00000000000000000005605 93.0
WH2_k127_3162491_0 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 516.0
WH2_k127_3162491_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 404.0
WH2_k127_3162491_10 - - - - 0.00000000000000000000000000000000000000000000002741 172.0
WH2_k127_3162491_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 335.0
WH2_k127_3162491_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 312.0
WH2_k127_3162491_4 COG3773 Cell wall hydrolyses involved in spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
WH2_k127_3162491_5 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002088 275.0
WH2_k127_3162491_6 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001954 257.0
WH2_k127_3162491_7 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001841 239.0
WH2_k127_3162491_8 Belongs to the HesB IscA family - - - 0.0000000000000000000000000000000000000000000000000000000984 196.0
WH2_k127_3162491_9 Protein of unknown function (DUF1491) - - - 0.0000000000000000000000000000000000000000000000006041 176.0
WH2_k127_317632_0 overlaps another CDS with the same product name K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 506.0
WH2_k127_317632_1 overlaps another CDS with the same product name K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 452.0
WH2_k127_317632_2 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 359.0
WH2_k127_317632_3 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.000000000000000000000000000000000000000000000000000000000000005766 216.0
WH2_k127_317632_4 Ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000000000001598 198.0
WH2_k127_3180536_0 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane K11103 - - 2.619e-240 750.0
WH2_k127_3180536_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 538.0
WH2_k127_3180536_2 receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000406 281.0
WH2_k127_3201483_0 Dehydrogenase K00101,K15054 - 1.1.2.3,1.1.99.31 3.637e-229 713.0
WH2_k127_3201483_1 - - - - 0.00000000000000000000000000000000000000000000000000000008403 199.0
WH2_k127_3201483_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000001044 113.0
WH2_k127_3201483_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00002848 47.0
WH2_k127_3207988_0 diguanylate cyclase K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 591.0
WH2_k127_3207988_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 565.0
WH2_k127_3207988_10 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000000000002725 233.0
WH2_k127_3207988_11 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000000000000000000006406 209.0
WH2_k127_3207988_12 - - - - 0.000000000000000000000000000000000000000000000000000000000194 212.0
WH2_k127_3207988_13 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000000000000222 154.0
WH2_k127_3207988_14 - - - - 0.0000000000000000000000000000000000000004264 151.0
WH2_k127_3207988_2 Flagellar basal body rod FlgEFG protein C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 480.0
WH2_k127_3207988_3 flagellar basal-body rod protein FlgG K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 462.0
WH2_k127_3207988_4 transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 457.0
WH2_k127_3207988_5 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 417.0
WH2_k127_3207988_6 flagellar basal body K02391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 412.0
WH2_k127_3207988_7 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 342.0
WH2_k127_3207988_8 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 342.0
WH2_k127_3207988_9 Chaperone for flagella basal body P-ring formation K02386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 286.0
WH2_k127_3221948_0 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 396.0
WH2_k127_3221948_1 Bacterial type II/III secretion system short domain K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 305.0
WH2_k127_3221948_10 general secretion pathway protein K K02460 - - 0.0000000000000000000007205 106.0
WH2_k127_3221948_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 287.0
WH2_k127_3221948_3 Protein of unknown function (DUF1109) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004887 260.0
WH2_k127_3221948_4 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009917 246.0
WH2_k127_3221948_5 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000002073 226.0
WH2_k127_3221948_6 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000000000000000009029 218.0
WH2_k127_3221948_7 - - - - 0.0000000000000000000000000000000000000000004001 159.0
WH2_k127_3221948_8 Cell Wall Hydrolase - - - 0.0000000000000000000000000000000000000003282 166.0
WH2_k127_3221948_9 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000000000000000000000609 133.0
WH2_k127_3228536_0 enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 467.0
WH2_k127_3228536_1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 399.0
WH2_k127_3228536_2 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 375.0
WH2_k127_3228536_3 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000004182 140.0
WH2_k127_3261567_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 604.0
WH2_k127_3261567_1 Cell Wall - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 502.0
WH2_k127_3261567_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 355.0
WH2_k127_3261567_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 304.0
WH2_k127_3261567_4 - - - - 0.000000000000000000000000000000000000006391 149.0
WH2_k127_328585_0 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes K00639,K00652 - 2.3.1.29,2.3.1.47 4.222e-253 782.0
WH2_k127_328585_1 Terminase RNaseH-like domain - - - 0.0000000000000000000000000000000000000000000000000000000003255 213.0
WH2_k127_328585_2 - - - - 0.000000000000000000000000000000000000000000000000000005642 195.0
WH2_k127_328585_3 acyl carrier protein - - - 0.000000000000000000000000000000000001436 138.0
WH2_k127_3300066_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 5.746e-200 631.0
WH2_k127_3300066_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 532.0
WH2_k127_3331233_0 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 427.0
WH2_k127_3331233_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 354.0
WH2_k127_3331233_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 347.0
WH2_k127_3331233_3 Male sterility protein K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003836 270.0
WH2_k127_3354763_0 Acetyl-coenzyme A transporter 1 - - - 1.942e-223 700.0
WH2_k127_3354763_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 438.0
WH2_k127_3354763_2 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 322.0
WH2_k127_3354763_3 EamA-like transporter family K15268 - - 0.000000000000000000000202 96.0
WH2_k127_3372346_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 299.0
WH2_k127_3372346_1 Oligoketide cyclase lipid transport protein K18588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 294.0
WH2_k127_3372346_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000594 276.0
WH2_k127_3372346_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000001612 192.0
WH2_k127_3372346_4 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000008798 131.0
WH2_k127_3379683_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 1.435e-237 737.0
WH2_k127_3379683_1 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 571.0
WH2_k127_3379683_2 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 478.0
WH2_k127_3379683_3 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 304.0
WH2_k127_3379683_4 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000456 248.0
WH2_k127_3379683_5 small integral membrane protein - - - 0.0000000000000000000000000000000000000000000002372 174.0
WH2_k127_3379683_6 beta-lactamase activity K07126 - - 0.00000000414 64.0
WH2_k127_3383090_0 Domain of unknown function (DUF305) - - - 0.0 1248.0
WH2_k127_3383090_1 beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 563.0
WH2_k127_3383090_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 554.0
WH2_k127_3383090_3 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 543.0
WH2_k127_3383090_4 - - - - 0.0000000000000000000000009243 106.0
WH2_k127_3443019_0 Outer membrane efflux protein - - - 7.148e-222 698.0
WH2_k127_3443019_1 FtsX-like permease family - - - 2.925e-210 657.0
WH2_k127_3443019_2 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 506.0
WH2_k127_3443019_3 ABC transporter, ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 459.0
WH2_k127_3443019_4 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 284.0
WH2_k127_3520643_0 Riboflavin synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 373.0
WH2_k127_3520643_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 340.0
WH2_k127_3520643_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 303.0
WH2_k127_3520643_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000566 200.0
WH2_k127_3520643_4 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000146 146.0
WH2_k127_3520643_5 PFAM Aminotransferase class I and II K00832 - 2.6.1.57 0.000000001085 59.0
WH2_k127_3534309_0 FMN-dependent dehydrogenase K00467 - 1.13.12.4 6.251e-248 766.0
WH2_k127_3534309_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 353.0
WH2_k127_3534309_2 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000000000000000000000000000000003569 202.0
WH2_k127_3544206_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 1.114e-245 763.0
WH2_k127_3544206_1 glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 578.0
WH2_k127_3544206_2 Belongs to the Nudix hydrolase family K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 546.0
WH2_k127_3544206_3 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 331.0
WH2_k127_3544206_4 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 300.0
WH2_k127_3544206_5 membrane - - - 0.000000000000000000000000002862 117.0
WH2_k127_354617_0 Cysteine synthase K01738 - 2.5.1.47 1.122e-208 652.0
WH2_k127_354617_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 541.0
WH2_k127_354617_2 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 492.0
WH2_k127_354617_3 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 312.0
WH2_k127_354617_4 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 287.0
WH2_k127_354617_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 295.0
WH2_k127_354617_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 282.0
WH2_k127_354617_7 ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000000000000000004136 209.0
WH2_k127_354617_8 Domain of unknown function (DUF1905) - - - 0.000000000000000000000000000000000000000000000000000002014 193.0
WH2_k127_354617_9 - - - - 0.0000000000000000000000000000000000001854 145.0
WH2_k127_3560018_0 Phosphatidylethanolamine-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 340.0
WH2_k127_3560018_1 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003653 249.0
WH2_k127_3560018_2 DoxX-like family - - - 0.00000000000000000000000000000000000000000000000000000000000765 209.0
WH2_k127_3560018_3 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000001959 166.0
WH2_k127_3560018_4 COG5531 SWIB-domain-containing proteins implicated in chromatin remodeling - - - 0.00000000000000000000000000000000000000000002125 161.0
WH2_k127_3560018_5 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.000000000002557 74.0
WH2_k127_3567529_0 Belongs to the GMC oxidoreductase family - - - 0.0 998.0
WH2_k127_3567529_1 sterol desaturase - - - 3.657e-194 607.0
WH2_k127_3567529_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000008731 229.0
WH2_k127_3567529_3 - - - - 0.00000000000000000000000000000005361 130.0
WH2_k127_3567529_4 Cold shock protein domain K03704 - - 0.000000000000000000000000006658 111.0
WH2_k127_3574743_0 nucleoside K03317 - - 1.563e-261 812.0
WH2_k127_3574743_1 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 586.0
WH2_k127_3574743_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 376.0
WH2_k127_3574743_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002003 264.0
WH2_k127_3574743_4 - - - - 0.000000000000000000000000000000000000000000000000003127 183.0
WH2_k127_3610023_0 acetyltransferase - - - 9.76e-224 696.0
WH2_k127_3610023_1 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 613.0
WH2_k127_3610023_2 In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 394.0
WH2_k127_3610023_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 351.0
WH2_k127_3623411_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 511.0
WH2_k127_3623411_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 363.0
WH2_k127_3623411_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000004317 111.0
WH2_k127_3635977_0 Bacterial type II/III secretion system short domain K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001172 280.0
WH2_k127_3635977_1 PFAM Fimbrial assembly family protein K02461,K02662,K02663 - - 0.0000000000000000000000000000009111 135.0
WH2_k127_3635977_2 General Secretion Pathway protein K02459 - - 0.00000000000000000000000002819 115.0
WH2_k127_3647757_0 Major facilitator superfamily K03446 - - 7.351e-291 899.0
WH2_k127_3647757_1 Secretion protein, HlyD K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 445.0
WH2_k127_3647757_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 373.0
WH2_k127_3647757_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 284.0
WH2_k127_3670962_0 CobN/Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.0 2179.0
WH2_k127_3670962_1 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04039 - 1.3.7.7 2.532e-314 965.0
WH2_k127_3670962_2 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04038 - 1.3.7.7 1.843e-209 652.0
WH2_k127_3670962_3 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP K02588,K04037 - 1.18.6.1,1.3.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 588.0
WH2_k127_3670962_4 Magnesium-protoporphyrin IX methyltransferase C-terminus K03428 - 2.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 425.0
WH2_k127_3670962_5 PUCC protein K08226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 286.0
WH2_k127_3673321_0 UDP binding domain K00066 - 1.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 542.0
WH2_k127_3673321_1 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 419.0
WH2_k127_3673321_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 395.0
WH2_k127_3780633_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 560.0
WH2_k127_3780633_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 475.0
WH2_k127_3780633_2 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 397.0
WH2_k127_3780633_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 391.0
WH2_k127_3780633_4 - - - - 0.00000000000000000000000000000004464 137.0
WH2_k127_3787422_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1124.0
WH2_k127_3787422_1 LppC putative lipoprotein - - - 6.798e-202 634.0
WH2_k127_3787422_2 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 581.0
WH2_k127_3787422_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 360.0
WH2_k127_3788201_0 Peptidase, M16 K07263 - - 1.197e-233 729.0
WH2_k127_3788201_1 Nitroreductase family K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 370.0
WH2_k127_3788201_2 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 359.0
WH2_k127_3788201_3 peptidase M22 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 284.0
WH2_k127_3788201_4 Acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000003327 165.0
WH2_k127_3791375_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 4.94e-322 989.0
WH2_k127_3791375_1 tRNA synthetase, class II K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008848 450.0
WH2_k127_3791375_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 293.0
WH2_k127_3828427_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1137.0
WH2_k127_3828427_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 1.418e-246 763.0
WH2_k127_3828427_2 Transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 557.0
WH2_k127_3828427_3 energy transducer activity K03646,K03832 - - 0.00000000000000000000000128 109.0
WH2_k127_3828427_5 Homocysteine S-methyltransferase - - - 0.00000006489 53.0
WH2_k127_3835903_0 acyl-CoA dehydrogenase - - - 0.0 1165.0
WH2_k127_3835903_1 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 367.0
WH2_k127_3835903_2 Competence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 287.0
WH2_k127_3835903_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000514 279.0
WH2_k127_3835903_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000000000000001386 206.0
WH2_k127_3835903_5 depolymerase - - - 0.00000000000000000000000000000000001629 141.0
WH2_k127_386004_0 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 609.0
WH2_k127_386004_1 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000000000000000000000003103 227.0
WH2_k127_3877774_0 Peptidase family S41 - - - 3.699e-229 717.0
WH2_k127_3877774_1 FAD binding domain of DNA photolyase - - - 1.514e-205 645.0
WH2_k127_3877774_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003613 269.0
WH2_k127_3877774_3 membrane - - - 0.00000000000000000000000000000000000000000000000001848 183.0
WH2_k127_3878646_0 Belongs to the peptidase M16 family K07263 - - 0.0 1486.0
WH2_k127_3878646_1 receptor K02014 - - 0.0 1264.0
WH2_k127_3878646_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000001139 139.0
WH2_k127_3878646_11 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000000000003816 102.0
WH2_k127_3878646_12 Resolvase - - - 0.00001019 53.0
WH2_k127_3878646_2 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0 1082.0
WH2_k127_3878646_3 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 3.193e-255 789.0
WH2_k127_3878646_4 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 542.0
WH2_k127_3878646_5 ribonuclease E activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 474.0
WH2_k127_3878646_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 424.0
WH2_k127_3878646_7 Outer membrane receptor proteins, mostly Fe transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 308.0
WH2_k127_3878646_8 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000009296 238.0
WH2_k127_3878646_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000000000001141 169.0
WH2_k127_3899125_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 6.364e-304 940.0
WH2_k127_3899125_1 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 379.0
WH2_k127_3899125_2 PEP-CTERM motif - - - 0.00000000000000000000000000000000000000000000000000000108 200.0
WH2_k127_3899125_3 Protein of unknown function (DUF3500) K02051 - - 0.000000000000000000000000000000000000000000000000003325 196.0
WH2_k127_3899125_4 ArsR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000004866 162.0
WH2_k127_3899125_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000005278 66.0
WH2_k127_3899125_6 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000008464 58.0
WH2_k127_3906699_0 membrane metal-binding protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 597.0
WH2_k127_3906699_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 580.0
WH2_k127_3906699_2 molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 558.0
WH2_k127_3906699_3 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 445.0
WH2_k127_3906699_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 411.0
WH2_k127_3906699_5 with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002912 265.0
WH2_k127_3906699_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000005292 252.0
WH2_k127_3907907_0 TonB dependent receptor - - - 7.269e-298 928.0
WH2_k127_3907907_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000002812 64.0
WH2_k127_3920916_0 Belongs to the glycosyl hydrolase 31 family K15922 - 3.2.1.199 5.333e-282 875.0
WH2_k127_3920916_1 TonB dependent receptor K02014 - - 4.244e-272 845.0
WH2_k127_396924_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 480.0
WH2_k127_396924_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 398.0
WH2_k127_396924_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 359.0
WH2_k127_396924_3 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 358.0
WH2_k127_396924_4 Methionine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 290.0
WH2_k127_3969798_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.111e-206 647.0
WH2_k127_3969798_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 403.0
WH2_k127_3969798_2 membrane K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001668 258.0
WH2_k127_3990677_0 sorbosone - - - 7.24e-260 818.0
WH2_k127_3990677_1 ATPase (AAA superfamily) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 421.0
WH2_k127_3990677_2 GAF domain-containing protein K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005043 275.0
WH2_k127_3990677_3 acyl-CoA dehydrogenase K20035 - - 0.000000000000000000000000000000000000000001944 157.0
WH2_k127_3990677_4 Outer membrane lipoprotein - - - 0.0003798 44.0
WH2_k127_4016571_0 Penicillin-binding Protein K05515 - 3.4.16.4 0.0 1260.0
WH2_k127_4016571_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 426.0
WH2_k127_4016571_2 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 312.0
WH2_k127_4016571_3 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 301.0
WH2_k127_402907_0 protein conserved in bacteria K09799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 606.0
WH2_k127_402907_1 Bile acid sodium symporter K14347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 532.0
WH2_k127_402907_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 459.0
WH2_k127_402907_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007515 368.0
WH2_k127_4073922_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1201.0
WH2_k127_4073922_1 Protein of unknown function (DUF3667) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 342.0
WH2_k127_4073922_2 AefR-like transcriptional repressor, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 327.0
WH2_k127_4073922_3 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 284.0
WH2_k127_4073922_4 FtsX-like permease family - - - 0.00000000000003324 72.0
WH2_k127_409072_0 CheA signal transduction histidine kinase K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 574.0
WH2_k127_409072_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 383.0
WH2_k127_409072_2 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 365.0
WH2_k127_409072_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 334.0
WH2_k127_409072_4 CheW-like domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000000001119 220.0
WH2_k127_409072_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000001801 209.0
WH2_k127_409072_6 response regulator K03413 - - 0.000000000000000000000000000000000000000000000000000005979 192.0
WH2_k127_409072_7 chemotaxis protein K03406 - - 0.000000000000000000000000000000000001179 146.0
WH2_k127_409072_8 STAS domain - - - 0.0000000000002 76.0
WH2_k127_4133130_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 2.352e-196 615.0
WH2_k127_4133130_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000001649 259.0
WH2_k127_4137736_0 Cytochrome P450 - - - 2.809e-257 798.0
WH2_k127_4137736_1 Cytochrome P450 - - - 1.087e-201 629.0
WH2_k127_4137736_2 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 363.0
WH2_k127_4137736_3 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 325.0
WH2_k127_4137736_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 313.0
WH2_k127_4137736_5 Limonene-1,2-epoxide hydrolase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001707 230.0
WH2_k127_4137736_6 - - - - 0.000000000000000000000000000000000000000000004017 169.0
WH2_k127_4137736_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000004049 143.0
WH2_k127_4164666_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 1.699e-266 825.0
WH2_k127_4164666_1 S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase K13622 - - 4.052e-251 777.0
WH2_k127_4164666_2 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 531.0
WH2_k127_4164666_3 ubiE/COQ5 methyltransferase family K13623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 266.0
WH2_k127_4164666_4 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000001234 134.0
WH2_k127_4164666_5 NHL repeat - - - 0.00000005122 56.0
WH2_k127_4195012_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 7.65e-227 717.0
WH2_k127_4195012_1 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000007502 218.0
WH2_k127_4195012_2 COG1403 Restriction endonuclease - - - 0.0000000000000000000000196 104.0
WH2_k127_4195012_3 Reductase - - - 0.0006651 42.0
WH2_k127_4227965_0 Peptidase family M1 domain - - - 0.0 1517.0
WH2_k127_4227965_1 TonB dependent receptor K02014 - - 0.0 1354.0
WH2_k127_4227965_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 1137.0
WH2_k127_4227965_3 Alkaline phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 507.0
WH2_k127_4227965_4 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 444.0
WH2_k127_4227965_5 - - - - 0.0000000000000000000000000000000000000000000000000000001343 208.0
WH2_k127_4227965_6 of PP-loop superfamily - - - 0.00000000000000000000000000004788 118.0
WH2_k127_4242919_0 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 535.0
WH2_k127_4242919_1 Binding-protein-dependent transport system inner membrane component K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 332.0
WH2_k127_4270091_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1108.0
WH2_k127_4270091_1 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000254 265.0
WH2_k127_4335094_0 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 406.0
WH2_k127_4335094_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001507 277.0
WH2_k127_4335094_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001529 259.0
WH2_k127_4335094_3 Sensors of blue-light using FAD - - - 0.0000000000000000000000000000000000000000000000000000000000000000003104 230.0
WH2_k127_4335094_4 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002752 222.0
WH2_k127_4335094_5 - - - - 0.00000000000000000000000000000000000001089 145.0
WH2_k127_4337454_0 Adenylate cyclase - - - 3.029e-221 697.0
WH2_k127_4337454_1 Esterase-like activity of phytase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 472.0
WH2_k127_4337454_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000006251 264.0
WH2_k127_4337454_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000000000000002089 249.0
WH2_k127_4337454_4 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000001178 191.0
WH2_k127_4337454_5 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000000000000000006707 179.0
WH2_k127_4337454_6 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.0000000000000000000000000000006163 122.0
WH2_k127_4337454_7 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000000000000000000001909 124.0
WH2_k127_4337454_8 enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000002911 108.0
WH2_k127_4351783_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 0.0 1144.0
WH2_k127_4351783_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.497e-209 661.0
WH2_k127_4351783_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 606.0
WH2_k127_4351783_3 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 605.0
WH2_k127_4351783_4 Transporter K02429 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 606.0
WH2_k127_4351783_5 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 537.0
WH2_k127_4351783_6 Aldolase K01625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 338.0
WH2_k127_4356838_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0 1266.0
WH2_k127_4356838_1 Glutathione S-transferase K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 504.0
WH2_k127_4356838_2 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001554 274.0
WH2_k127_4379782_0 Aminotransferase K14261 - - 5.728e-206 641.0
WH2_k127_4379782_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001653 261.0
WH2_k127_4379782_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005892 235.0
WH2_k127_4379782_3 - - - - 0.000000000000000000000000000000000000000000006475 166.0
WH2_k127_4393823_0 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 0.0 1349.0
WH2_k127_4393823_1 Transporter - - - 9.476e-272 845.0
WH2_k127_4393823_2 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 499.0
WH2_k127_4393823_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 402.0
WH2_k127_4393823_4 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 321.0
WH2_k127_4393823_5 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 296.0
WH2_k127_4393823_6 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000003535 224.0
WH2_k127_4393823_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000213 185.0
WH2_k127_4393823_8 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000002162 93.0
WH2_k127_443748_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.125e-278 859.0
WH2_k127_443748_1 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 514.0
WH2_k127_443748_2 Lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 461.0
WH2_k127_445563_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1602.0
WH2_k127_4456728_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0 1093.0
WH2_k127_4456728_1 belongs to the aldehyde dehydrogenase family - - - 7.745e-225 699.0
WH2_k127_4456728_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 587.0
WH2_k127_4456728_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 578.0
WH2_k127_445706_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 414.0
WH2_k127_445706_1 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 386.0
WH2_k127_445706_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000005929 229.0
WH2_k127_448595_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1092.0
WH2_k127_448595_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 8.359e-205 642.0
WH2_k127_448595_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 537.0
WH2_k127_448595_3 Protein of unknown function (DUF1153) - - - 0.0000000000000000000000000000000000000000000000000000001852 196.0
WH2_k127_448595_4 - - - - 0.000000000000000000000000000000000000000000000000005746 184.0
WH2_k127_448595_5 Transglycosylase associated protein - - - 0.0000000000000000000004442 96.0
WH2_k127_448595_6 Transglycosylase associated protein - - - 0.0000001122 54.0
WH2_k127_4616977_0 Membrane protein involved in the export of O-antigen and teichoic acid - - - 1.057e-241 756.0
WH2_k127_4616977_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 461.0
WH2_k127_4616977_2 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 329.0
WH2_k127_4617053_0 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 5.82e-247 765.0
WH2_k127_4617053_1 Thiol disulfide interchange protein - - - 0.00000000000000000003423 99.0
WH2_k127_4617053_2 - - - - 0.0000000003523 60.0
WH2_k127_4660621_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 556.0
WH2_k127_4660621_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 314.0
WH2_k127_4660621_2 acyl carrier protein - - - 0.0000000000000000000000000000000000000000000000001028 178.0
WH2_k127_4691020_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0 1001.0
WH2_k127_4691020_1 Helicase K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 595.0
WH2_k127_4691020_2 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 392.0
WH2_k127_4691020_3 Nickel/cobalt transporter regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 297.0
WH2_k127_4691042_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 5.565e-244 758.0
WH2_k127_4691042_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 537.0
WH2_k127_4691042_2 - - - - 0.0000000000000000000000000000000000000000000000000116 182.0
WH2_k127_4713931_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 8.567e-321 987.0
WH2_k127_4713931_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 8.122e-275 854.0
WH2_k127_4713931_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 591.0
WH2_k127_4713931_3 2-methylthioadenine K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 517.0
WH2_k127_4713931_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 462.0
WH2_k127_4713931_5 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009878 250.0
WH2_k127_4713931_6 - - - - 0.0000000000000000000000463 100.0
WH2_k127_4714052_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 559.0
WH2_k127_4714052_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 488.0
WH2_k127_4748281_0 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 5.228e-265 823.0
WH2_k127_4748281_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.011e-239 743.0
WH2_k127_4748281_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 516.0
WH2_k127_4757066_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 2.458e-266 826.0
WH2_k127_4757066_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.332e-250 777.0
WH2_k127_4757066_2 Belongs to the SEDS family K03588 - - 4.997e-228 710.0
WH2_k127_4757066_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 7.884e-225 710.0
WH2_k127_4757066_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 2.271e-216 673.0
WH2_k127_4757066_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 462.0
WH2_k127_4757066_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000002386 225.0
WH2_k127_4765877_0 Methionine synthase I (cobalamin-dependent), methyltransferase domain K00548 - 2.1.1.13 3.62e-203 636.0
WH2_k127_4765877_1 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 4.276e-200 625.0
WH2_k127_4765877_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000001599 75.0
WH2_k127_4769126_0 Oxidoreductase FAD-binding domain K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 563.0
WH2_k127_4769126_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 328.0
WH2_k127_4769126_2 LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 315.0
WH2_k127_479239_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 592.0
WH2_k127_479239_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 466.0
WH2_k127_479239_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000003693 188.0
WH2_k127_4793921_0 protein conserved in bacteria K09800 - - 0.0 1469.0
WH2_k127_4793921_1 lysozyme K01185 - 3.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 305.0
WH2_k127_4793921_2 - - - - 0.0000000000000000000000000000000000000002478 153.0
WH2_k127_4793921_3 Helix-turn-helix domain K07729 - - 0.000000000000000000000000000000000119 133.0
WH2_k127_4799234_0 NMT1/THI5 like K02051 - - 3.057e-199 625.0
WH2_k127_4799234_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 346.0
WH2_k127_4799234_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000003635 216.0
WH2_k127_4799234_3 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000006971 156.0
WH2_k127_4802046_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1079.0
WH2_k127_4802046_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 8.839e-305 942.0
WH2_k127_4802046_2 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000007268 180.0
WH2_k127_4802046_3 - - - - 0.0000000000468 64.0
WH2_k127_486767_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1184.0
WH2_k127_486767_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 292.0
WH2_k127_486767_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000005022 217.0
WH2_k127_487981_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05577 - 1.6.5.3 1.703e-254 794.0
WH2_k127_487981_1 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 484.0
WH2_k127_487981_2 COG0332 3-oxoacyl- acyl-carrier-protein synthase III K16872 - 2.3.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 366.0
WH2_k127_487981_3 Belongs to the UPF0753 family K09822 - - 0.000000000000000000000000000000000000000000004717 171.0
WH2_k127_4948962_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.626e-274 846.0
WH2_k127_4948962_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 1.625e-220 685.0
WH2_k127_4948962_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 421.0
WH2_k127_4948962_3 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 310.0
WH2_k127_4948962_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003942 244.0
WH2_k127_4948962_5 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001544 242.0
WH2_k127_4948962_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000000000009289 231.0
WH2_k127_4948962_7 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000001444 211.0
WH2_k127_5010209_0 PFAM glycosyl transferase group 1 - - - 9.251e-246 763.0
WH2_k127_5010209_1 polysaccharide K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 412.0
WH2_k127_5010209_2 ABC transporter K01990,K09689 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 397.0
WH2_k127_5010209_3 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 370.0
WH2_k127_5010209_4 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 359.0
WH2_k127_5010209_5 Transporter K01992,K09688 - - 0.00000000000000000000000000007504 116.0
WH2_k127_5042743_0 PFAM Rieske 2Fe-2S domain - - - 2.452e-293 902.0
WH2_k127_5042743_1 Acts as a magnesium transporter K06213 - - 5.129e-251 778.0
WH2_k127_5042743_2 cobalamin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 492.0
WH2_k127_5042743_3 Enoyl-(Acyl carrier protein) reductase K18335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 448.0
WH2_k127_5042743_4 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 291.0
WH2_k127_5042743_5 Protein of unknown function (DUF1489) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001773 240.0
WH2_k127_5042743_6 - - - - 0.0000000000000000000000000000000000000000000001051 177.0
WH2_k127_5042743_7 Protein of unknown function (DUF1489) - - - 0.000000001039 59.0
WH2_k127_5059920_0 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 511.0
WH2_k127_5059920_1 Chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 459.0
WH2_k127_5059920_2 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 346.0
WH2_k127_5084154_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K18688 - 6.2.1.42 4.833e-300 924.0
WH2_k127_5084154_1 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 416.0
WH2_k127_5084154_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 291.0
WH2_k127_5084154_3 dioxygenase of extradiol dioxygenase family K06991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003532 266.0
WH2_k127_5084154_4 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000007908 218.0
WH2_k127_510740_0 Rieske 2Fe-2S - - - 6.135e-307 955.0
WH2_k127_510740_1 Xylose isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 462.0
WH2_k127_510740_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 447.0
WH2_k127_510740_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 326.0
WH2_k127_510740_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 291.0
WH2_k127_511734_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1337.0
WH2_k127_511734_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 374.0
WH2_k127_511734_2 Deoxyribodipyrimidine photo-lyase K06876 - - 0.00000000000000000000000000002971 118.0
WH2_k127_511747_0 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 493.0
WH2_k127_511747_1 Hemolysin K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 453.0
WH2_k127_511747_2 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.000000000000000000000000000000000000000000003279 168.0
WH2_k127_511747_3 - - - - 0.0000000000000000000000000000000001877 140.0
WH2_k127_5123378_0 of ABC transporters with duplicated ATPase K15738 - - 0.0 1088.0
WH2_k127_5123378_1 Histidine kinase - - - 3.752e-273 845.0
WH2_k127_5123378_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 373.0
WH2_k127_5123378_3 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 332.0
WH2_k127_5123378_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 303.0
WH2_k127_5123378_5 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001498 277.0
WH2_k127_5123378_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004507 226.0
WH2_k127_5123378_7 XRE family transcriptional regulator - - - 0.000000000000000000000000000000000000000000002625 168.0
WH2_k127_5123378_8 - - - - 0.000000000000000000000000000000000000006402 148.0
WH2_k127_5139532_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 5.715e-200 633.0
WH2_k127_5139532_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 491.0
WH2_k127_5139532_2 Methanol dehydrogenase K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 435.0
WH2_k127_5139532_3 membrane K08988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 398.0
WH2_k127_5139532_4 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 349.0
WH2_k127_5139532_5 Nudix hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 344.0
WH2_k127_5139532_6 PspC domain - - - 0.000000000000000000000000000000001371 132.0
WH2_k127_5139532_7 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000002084 67.0
WH2_k127_51558_0 protein conserved in bacteria - - - 2.014e-212 679.0
WH2_k127_51558_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 592.0
WH2_k127_51558_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 574.0
WH2_k127_51558_3 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 452.0
WH2_k127_51558_4 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 391.0
WH2_k127_51558_5 ATPase involved in DNA replication - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 332.0
WH2_k127_51558_6 Domain of unknown function (DUF4328) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 286.0
WH2_k127_51558_7 Protein of unknown function (DUF2794) - - - 0.000000000000000000000000000000000000000000000000000000000000000004987 226.0
WH2_k127_5156882_0 ATP-dependent helicase K03579 - 3.6.4.13 0.0 1352.0
WH2_k127_5156882_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 2.849e-295 912.0
WH2_k127_5156882_2 ETC complex I subunit - - - 0.0000000000000000000000000000000000000000000008189 166.0
WH2_k127_5166814_0 Sulfatase - - - 3.798e-222 694.0
WH2_k127_5166814_1 Serine aminopeptidase, S33 K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 551.0
WH2_k127_517586_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 589.0
WH2_k127_517586_1 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 376.0
WH2_k127_517586_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 338.0
WH2_k127_5204198_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 4.482e-241 749.0
WH2_k127_5204198_1 Transmembrane secretion effector - - - 9.602e-220 687.0
WH2_k127_5204198_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 285.0
WH2_k127_5204198_3 PilZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000533 207.0
WH2_k127_5218436_0 5-aminolevulinic acid synthase K00643 - 2.3.1.37 1.443e-230 715.0
WH2_k127_5218436_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 430.0
WH2_k127_5218436_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 308.0
WH2_k127_5218436_3 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001006 280.0
WH2_k127_5229596_0 Aminomethyltransferase K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 407.0
WH2_k127_5229596_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 309.0
WH2_k127_5229596_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000004071 238.0
WH2_k127_5229596_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000000000000008811 202.0
WH2_k127_5229596_4 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000000000002961 173.0
WH2_k127_523781_0 Acetyl-CoA acetyltransferase - - - 1.188e-247 769.0
WH2_k127_523781_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 407.0
WH2_k127_523781_2 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 283.0
WH2_k127_523781_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001414 271.0
WH2_k127_5263117_0 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 424.0
WH2_k127_5263117_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 329.0
WH2_k127_5263117_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001591 258.0
WH2_k127_5263781_0 PAS fold - - - 0.0 1717.0
WH2_k127_5263781_1 Major Facilitator - - - 2e-323 995.0
WH2_k127_5263781_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 506.0
WH2_k127_5263781_3 META domain - - - 0.0000000000000000000000000000000000000000000000000000000000001109 214.0
WH2_k127_5263781_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000104 205.0
WH2_k127_5263781_5 - - - - 0.00000000000000000000000000000000000008253 147.0
WH2_k127_528319_0 Asparagine synthase K01953 - 6.3.5.4 0.0 1170.0
WH2_k127_528319_1 AFG1 family ATPase K06916 - - 4.799e-215 671.0
WH2_k127_528319_10 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000001558 68.0
WH2_k127_528319_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 542.0
WH2_k127_528319_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 531.0
WH2_k127_528319_4 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 465.0
WH2_k127_528319_5 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 471.0
WH2_k127_528319_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 394.0
WH2_k127_528319_7 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 381.0
WH2_k127_528319_8 protein, possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 285.0
WH2_k127_528319_9 Glycosyl transferase - - - 0.00000000000000000000000000000006552 128.0
WH2_k127_5341298_0 Zinc carboxypeptidase - - - 0.0 1560.0
WH2_k127_5341298_1 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0 1331.0
WH2_k127_5341298_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.653e-246 764.0
WH2_k127_5341298_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 434.0
WH2_k127_5341298_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 346.0
WH2_k127_5341298_5 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000004239 117.0
WH2_k127_5341298_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000002574 58.0
WH2_k127_5372444_0 FAD linked - - - 6.689e-225 702.0
WH2_k127_5372444_1 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 479.0
WH2_k127_5372444_2 SapC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 419.0
WH2_k127_5417636_0 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000007741 101.0
WH2_k127_5417636_1 Hemolysin-type calcium-binding region - - - 0.0000008372 63.0
WH2_k127_5417843_0 COG3524 Capsule polysaccharide export protein K01992,K10107 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 378.0
WH2_k127_5417843_1 Transporter K01992,K09688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 341.0
WH2_k127_5417843_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 339.0
WH2_k127_5417843_3 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000002997 102.0
WH2_k127_5430858_0 acyl-CoA dehydrogenase K00252 - 1.3.8.6 1.41e-248 770.0
WH2_k127_5430858_1 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16171 - 3.7.1.2 2.704e-202 632.0
WH2_k127_5430858_2 maleylacetoacetate isomerase K01800 - 5.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 378.0
WH2_k127_5430858_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000003212 229.0
WH2_k127_5430858_4 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000003268 198.0
WH2_k127_5430858_5 rRNA binding - - - 0.00000000000001149 73.0
WH2_k127_5448632_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 4.218e-194 611.0
WH2_k127_5448632_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 442.0
WH2_k127_5448632_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 425.0
WH2_k127_5448632_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 297.0
WH2_k127_5457909_0 beta-galactosidase K12308 - 3.2.1.23 2.779e-229 713.0
WH2_k127_5457909_1 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 439.0
WH2_k127_5489191_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 6.044e-205 639.0
WH2_k127_5489191_1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 K18586 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 482.0
WH2_k127_5489191_2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 477.0
WH2_k127_5489191_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 394.0
WH2_k127_5489191_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001038 246.0
WH2_k127_5489191_5 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000004042 167.0
WH2_k127_5489480_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.305e-306 942.0
WH2_k127_5489480_1 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 554.0
WH2_k127_5489480_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000001826 130.0
WH2_k127_5503115_0 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.0 1917.0
WH2_k127_5503115_1 helicase K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 314.0
WH2_k127_5546880_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 528.0
WH2_k127_5546880_1 Belongs to the UPF0176 family K07146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 291.0
WH2_k127_5546880_2 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003561 273.0
WH2_k127_5546880_3 protein involved in cysteine biosynthesis K06203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003366 247.0
WH2_k127_5546880_4 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000000000000000000003505 233.0
WH2_k127_5546880_5 - - - - 0.00000000000000000000000000000000000000000002021 167.0
WH2_k127_5551174_0 Periplasmic copper-binding protein (NosD) - - - 3.832e-218 683.0
WH2_k127_5551174_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 533.0
WH2_k127_5551174_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 509.0
WH2_k127_5551174_3 Alpha beta hydrolase K18092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 439.0
WH2_k127_5551174_4 - - - - 0.000000000000000000000000000000000000000000000003467 175.0
WH2_k127_5570229_0 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 2.014e-243 755.0
WH2_k127_5570229_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 553.0
WH2_k127_5570229_2 Cold shock protein domain K03704 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 330.0
WH2_k127_5570229_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000002654 222.0
WH2_k127_5579476_0 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 505.0
WH2_k127_5579476_1 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004731 243.0
WH2_k127_559118_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 486.0
WH2_k127_559118_1 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 477.0
WH2_k127_559118_2 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 325.0
WH2_k127_559118_3 Entericidin EcnA/B family - - - 0.0000000000005705 70.0
WH2_k127_5605145_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 3.867e-258 800.0
WH2_k127_5605145_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 554.0
WH2_k127_5605145_10 invasion associated locus B - - - 0.000000000000000000000000000000000000000000000000000013 193.0
WH2_k127_5605145_11 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000000000000000000007938 186.0
WH2_k127_5605145_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 432.0
WH2_k127_5605145_3 periplasmic protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 404.0
WH2_k127_5605145_4 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 356.0
WH2_k127_5605145_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 349.0
WH2_k127_5605145_6 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 338.0
WH2_k127_5605145_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005608 255.0
WH2_k127_5605145_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006315 250.0
WH2_k127_5605145_9 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005571 226.0
WH2_k127_5621077_0 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 599.0
WH2_k127_5621077_1 Peptidase, M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 565.0
WH2_k127_5658304_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001647 259.0
WH2_k127_5658304_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000003068 201.0
WH2_k127_5658304_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000002491 74.0
WH2_k127_5662193_0 pathway protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 610.0
WH2_k127_5662193_1 type II secretion system K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 345.0
WH2_k127_5662193_2 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000004159 172.0
WH2_k127_5662193_3 type IV pilus modification protein PilV K02458 - - 0.0002575 49.0
WH2_k127_5686623_0 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 493.0
WH2_k127_5686623_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 486.0
WH2_k127_5686623_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 466.0
WH2_k127_5695152_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.59e-254 801.0
WH2_k127_5695152_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 2.233e-200 625.0
WH2_k127_5695152_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000001007 247.0
WH2_k127_5695152_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000762 240.0
WH2_k127_5695152_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000002168 197.0
WH2_k127_5791122_0 peptidase S9 K01278 - 3.4.14.5 0.0 1345.0
WH2_k127_5791122_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 460.0
WH2_k127_5791122_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 441.0
WH2_k127_5791122_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000000000002386 225.0
WH2_k127_5791122_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01502 - 3.5.5.7 0.0000000000000000000000000000000000004852 140.0
WH2_k127_5837348_0 Sulfotransferase family - - - 3.214e-204 642.0
WH2_k127_5837348_1 - - - - 0.0000000000000000000000000000000000000000000000005714 180.0
WH2_k127_5837348_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000122 100.0
WH2_k127_5838580_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.432e-288 892.0
WH2_k127_5838580_1 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 452.0
WH2_k127_5838580_2 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007047 239.0
WH2_k127_5838580_3 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000000000001032 154.0
WH2_k127_5855450_0 helicase K16899 - 3.6.4.12 0.0 1560.0
WH2_k127_5855450_1 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 312.0
WH2_k127_5867182_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.542e-275 851.0
WH2_k127_5867182_1 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 318.0
WH2_k127_5867182_2 - - - - 0.0000000000000000000000000001406 116.0
WH2_k127_5867182_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000003227 89.0
WH2_k127_5880939_0 Cytochrome c3 - - - 0.0 1004.0
WH2_k127_5880939_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 501.0
WH2_k127_5880939_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 449.0
WH2_k127_5880939_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000008756 119.0
WH2_k127_58865_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.908e-263 818.0
WH2_k127_58865_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 546.0
WH2_k127_58865_2 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 478.0
WH2_k127_58865_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K13584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 466.0
WH2_k127_58865_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 357.0
WH2_k127_58865_5 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 334.0
WH2_k127_58865_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000335 261.0
WH2_k127_58865_7 - - - - 0.0000000000000000000000000000000000000000000000000000000001974 205.0
WH2_k127_5886555_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 1.097e-294 912.0
WH2_k127_5886555_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 3.757e-209 651.0
WH2_k127_5886555_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000161 263.0
WH2_k127_5886555_3 Putative toxin of bacterial toxin-antitoxin pair K09982 - - 0.000000000000000000000000000000000004221 139.0
WH2_k127_5886555_4 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000008352 127.0
WH2_k127_5895159_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 1.434e-254 788.0
WH2_k127_5895159_1 glycosyl transferase - - - 1.839e-210 663.0
WH2_k127_5895159_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 2.665e-203 639.0
WH2_k127_5895159_3 UDP binding domain K00066 - 1.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000006271 243.0
WH2_k127_5914196_0 Sulfite reductase K00381 - 1.8.1.2 7.239e-238 737.0
WH2_k127_5914196_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 2.436e-213 664.0
WH2_k127_5914196_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 602.0
WH2_k127_5914196_3 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 516.0
WH2_k127_5914196_4 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 483.0
WH2_k127_5914196_5 receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 292.0
WH2_k127_5914196_6 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000001905 171.0
WH2_k127_591955_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 5.59e-286 884.0
WH2_k127_591955_1 membrane-bound lytic murein transglycosylase K08304 - - 9.064e-204 640.0
WH2_k127_591955_10 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000944 213.0
WH2_k127_591955_11 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000001371 171.0
WH2_k127_591955_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 5.169e-201 628.0
WH2_k127_591955_3 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 473.0
WH2_k127_591955_4 protein conserved in bacteria K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 391.0
WH2_k127_591955_5 import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 370.0
WH2_k127_591955_6 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 368.0
WH2_k127_591955_7 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 329.0
WH2_k127_591955_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001776 234.0
WH2_k127_591955_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000001154 228.0
WH2_k127_5963315_0 Threonine synthase K01733 - 4.2.3.1 1.127e-271 839.0
WH2_k127_5963315_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 2.475e-196 616.0
WH2_k127_5963315_10 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000000000000000000003701 117.0
WH2_k127_5963315_11 - - - - 0.0000000000001079 76.0
WH2_k127_5963315_2 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 566.0
WH2_k127_5963315_3 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 481.0
WH2_k127_5963315_4 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 281.0
WH2_k127_5963315_5 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008665 248.0
WH2_k127_5963315_6 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000000000000008536 234.0
WH2_k127_5963315_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000001359 218.0
WH2_k127_5963315_8 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000000000000000000005641 177.0
WH2_k127_5963315_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000002398 132.0
WH2_k127_5983959_0 Major Facilitator Superfamily K08191 - - 1.933e-212 665.0
WH2_k127_5983959_1 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 512.0
WH2_k127_5983959_2 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 470.0
WH2_k127_5983959_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000005237 97.0
WH2_k127_5992496_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.277e-218 679.0
WH2_k127_5992496_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 582.0
WH2_k127_5992496_2 Pfam:Pyridox_oxidase - - - 0.00000000000000007102 80.0
WH2_k127_6022579_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 8.907e-261 807.0
WH2_k127_6022579_1 Membrane-bound metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 494.0
WH2_k127_6022579_2 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 323.0
WH2_k127_6022579_3 Disulfide bond formation protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 279.0
WH2_k127_6055025_0 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 605.0
WH2_k127_6055025_1 protein conserved in bacteria K09986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 330.0
WH2_k127_6055025_2 Acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 314.0
WH2_k127_6073035_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 601.0
WH2_k127_6073035_1 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 359.0
WH2_k127_6073035_2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000005986 92.0
WH2_k127_6082586_0 PAS fold - - - 3.906e-257 805.0
WH2_k127_6082586_1 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 574.0
WH2_k127_6082586_2 isomerase K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 424.0
WH2_k127_6082586_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 361.0
WH2_k127_6082586_4 Phytochrome region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 290.0
WH2_k127_6109732_0 Putative diguanylate phosphodiesterase - - - 0.0 1249.0
WH2_k127_6109732_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1172.0
WH2_k127_6109732_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 4.322e-271 861.0
WH2_k127_6109732_3 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 2.022e-218 681.0
WH2_k127_6109732_4 HNH endonuclease K07454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 479.0
WH2_k127_611295_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1528.0
WH2_k127_611295_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 381.0
WH2_k127_611295_2 Outer membrane protein (OmpH-like) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 360.0
WH2_k127_611295_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 296.0
WH2_k127_6114766_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1560.0
WH2_k127_6114766_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 298.0
WH2_k127_6114766_2 YCII-related domain K09780 - - 0.0000000000000000000000000000000000000000000000000000003093 194.0
WH2_k127_6150924_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 619.0
WH2_k127_6150924_1 Major facilitator superfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000281 272.0
WH2_k127_6150924_2 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002914 270.0
WH2_k127_6150924_3 6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000001191 225.0
WH2_k127_6170653_0 Hydantoin racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 495.0
WH2_k127_6170653_1 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 364.0
WH2_k127_6170653_2 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 337.0
WH2_k127_6170653_3 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003367 269.0
WH2_k127_6175166_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 7.127e-279 865.0
WH2_k127_6175166_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 3.186e-247 767.0
WH2_k127_6175166_2 Tetratricopeptide repeat - - - 1.994e-214 678.0
WH2_k127_6175166_3 Cell wall formation K01921 - 6.3.2.4 4.136e-196 620.0
WH2_k127_6175166_4 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 418.0
WH2_k127_6175166_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 393.0
WH2_k127_6175166_6 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 334.0
WH2_k127_6175166_7 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 325.0
WH2_k127_6175166_8 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 302.0
WH2_k127_6175166_9 - - - - 0.00000002158 58.0
WH2_k127_6204379_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.0 1104.0
WH2_k127_6204379_1 YjgP YjgQ family K07091 - - 5.777e-210 656.0
WH2_k127_6204379_2 Aminotransferase K14261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 396.0
WH2_k127_6204379_3 Phasin protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 343.0
WH2_k127_6204379_4 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 310.0
WH2_k127_6204379_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000000000000000009996 211.0
WH2_k127_6207440_0 Antirepressor regulating drug resistance - - - 6.809e-198 633.0
WH2_k127_6207440_1 metalloprotease K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 498.0
WH2_k127_6207440_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000005891 218.0
WH2_k127_6207440_3 - - - - 0.00000000000000000000000000000000000000000000000000000000001987 215.0
WH2_k127_6207440_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.000000000000003443 79.0
WH2_k127_624218_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.582e-233 724.0
WH2_k127_624218_1 Carbohydrate-selective porin, OprB family K07267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 392.0
WH2_k127_624218_2 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 332.0
WH2_k127_624218_3 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000000000000001994 160.0
WH2_k127_6255081_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1258.0
WH2_k127_6255081_1 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 531.0
WH2_k127_6255081_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 487.0
WH2_k127_6255081_3 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 437.0
WH2_k127_6255081_4 adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 296.0
WH2_k127_6255081_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001758 231.0
WH2_k127_6255081_6 Hypoxia induced protein conserved region - - - 0.00000000000000000000000000001121 119.0
WH2_k127_6259171_0 rod shape-determining protein MreB K03569 - - 4.698e-214 677.0
WH2_k127_6259171_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 499.0
WH2_k127_6259171_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001565 273.0
WH2_k127_627356_0 Proto-chlorophyllide reductase 57 kD subunit K11335 - 1.3.7.14,1.3.7.15 1.596e-301 926.0
WH2_k127_627356_1 Bacterial regulatory protein, Fis family - - - 2.313e-260 807.0
WH2_k127_627356_10 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04038 - 1.3.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000004799 255.0
WH2_k127_627356_11 - - - - 0.000000000000000000000000000000000003514 147.0
WH2_k127_627356_12 Antenna complex alpha/beta subunit K08926 - - 0.0000000000000000000000000000009527 121.0
WH2_k127_627356_2 geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 3.648e-248 769.0
WH2_k127_627356_3 PUCC protein K08226 - - 1.092e-211 666.0
WH2_k127_627356_4 The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis K08929 - - 4.534e-206 641.0
WH2_k127_627356_5 Belongs to the reaction center PufL M PsbA D family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 559.0
WH2_k127_627356_6 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 539.0
WH2_k127_627356_7 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 491.0
WH2_k127_627356_8 2-vinyl bacteriochlorophyllide hydratase (BCHF) K11336 - 4.2.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 303.0
WH2_k127_627356_9 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 310.0
WH2_k127_6284201_0 TonB-dependent receptor K02014 - - 6.25e-299 921.0
WH2_k127_6284201_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.874e-291 895.0
WH2_k127_6284201_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 4.082e-200 625.0
WH2_k127_6284201_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 426.0
WH2_k127_6284201_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 371.0
WH2_k127_6284201_5 Peptidase dimerisation domain K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 326.0
WH2_k127_6284201_6 thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004467 267.0
WH2_k127_6284201_7 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000000000000112 210.0
WH2_k127_6284201_8 Domain of unknown function (DUF1476) - - - 0.000000000000000000000000000000000000000000000000008215 183.0
WH2_k127_6284201_9 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000000000000008811 143.0
WH2_k127_6306176_0 Glycosyl hydrolase family 36 N-terminal domain K07407 - 3.2.1.22 5.942e-278 865.0
WH2_k127_6306176_1 beta-galactosidase K12308 - 3.2.1.23 8.013e-252 779.0
WH2_k127_6348835_0 Glycosyl-hydrolase 97 C-terminal, oligomerisation K01187 - 3.2.1.20 0.0 1181.0
WH2_k127_6348835_1 PUCC protein K08226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 547.0
WH2_k127_6348835_2 Glycogen debranching enzyme, glucanotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 445.0
WH2_k127_6348835_3 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08930 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000001795 57.0
WH2_k127_6405953_0 Aerobic cobaltochelatase subunit CobS K09882 - 6.6.1.2 9.935e-200 623.0
WH2_k127_6405953_1 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 557.0
WH2_k127_6405953_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 520.0
WH2_k127_6405953_3 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 398.0
WH2_k127_6405953_4 molecular chaperone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 351.0
WH2_k127_6405953_5 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003075 248.0
WH2_k127_6405953_6 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000000000000000000002315 157.0
WH2_k127_6444708_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 1.163e-231 721.0
WH2_k127_6444708_1 epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 306.0
WH2_k127_6444708_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 299.0
WH2_k127_6477831_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 2.733e-212 663.0
WH2_k127_6477831_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 558.0
WH2_k127_6477831_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 321.0
WH2_k127_6477831_3 Septum formation initiator - - - 0.0000000000000000000000000000000000000002657 151.0
WH2_k127_6499794_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 5.509e-247 768.0
WH2_k127_6499794_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 408.0
WH2_k127_6499794_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000565 57.0
WH2_k127_6663785_0 M42 glutamyl aminopeptidase - - - 1.01e-234 739.0
WH2_k127_6663785_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 359.0
WH2_k127_6663785_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000001987 227.0
WH2_k127_6705256_0 Putative diguanylate phosphodiesterase - - - 0.0 1112.0
WH2_k127_6705256_1 ABC1 family - - - 2.129e-272 841.0
WH2_k127_6705256_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 436.0
WH2_k127_6705256_3 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 362.0
WH2_k127_6705256_4 Protein of unknown function (DUF3429) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003295 251.0
WH2_k127_6706406_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1162.0
WH2_k127_6706406_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 544.0
WH2_k127_6706406_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 529.0
WH2_k127_6706406_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 346.0
WH2_k127_6706406_4 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000008441 231.0
WH2_k127_6706620_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1040.0
WH2_k127_6706620_1 AMP-binding enzyme C-terminal domain - - - 1.296e-264 817.0
WH2_k127_6706620_2 - - - - 0.00000000000000000000000000000000000001167 149.0
WH2_k127_676886_0 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 342.0
WH2_k127_676886_1 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 284.0
WH2_k127_676886_3 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.00000000000000000002356 96.0
WH2_k127_6787789_0 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 593.0
WH2_k127_6787789_1 Flavin containing amine oxidoreductase K06955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 452.0
WH2_k127_6787789_2 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 349.0
WH2_k127_6787789_3 Tryptophan halogenase K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 339.0
WH2_k127_6805431_0 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 2.382e-312 957.0
WH2_k127_6805431_1 Belongs to the peptidase M17 family K01255 - 3.4.11.1 4.187e-273 843.0
WH2_k127_6805431_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 482.0
WH2_k127_6805431_3 Sodium/calcium exchanger protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 432.0
WH2_k127_6805431_4 NLP P60 protein - - - 0.000000000000000000000000000000000000000000000000000000000003108 210.0
WH2_k127_6805431_5 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000000003944 209.0
WH2_k127_6805431_6 Domain of unknown function (DUF4163) - - - 0.00000000000000000000000000000000000000000000000000000002881 203.0
WH2_k127_6809041_0 signal peptide peptidase K04773 - - 8.526e-307 949.0
WH2_k127_6809041_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 4.402e-277 856.0
WH2_k127_6809041_10 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 317.0
WH2_k127_6809041_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 288.0
WH2_k127_6809041_12 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003986 241.0
WH2_k127_6809041_13 Protein of unknown function (DUF3297) - - - 0.00000000000000000000000000000000000000000000000000000002469 199.0
WH2_k127_6809041_14 BFD-like [2Fe-2S] binding domain K02192 - - 0.0000000000000000000000000002045 119.0
WH2_k127_6809041_15 - - - - 0.0000005539 52.0
WH2_k127_6809041_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.491e-262 816.0
WH2_k127_6809041_3 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit K01426 - 3.5.1.4 5.96e-247 771.0
WH2_k127_6809041_4 Protein of unknown function (DUF418) K07148 - - 3.45e-231 721.0
WH2_k127_6809041_5 dihydroorotase K01465 - 3.5.2.3 5.267e-228 711.0
WH2_k127_6809041_6 Sporulation related domain - - - 1.983e-201 637.0
WH2_k127_6809041_7 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 1.583e-200 630.0
WH2_k127_6809041_8 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 456.0
WH2_k127_6809041_9 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 448.0
WH2_k127_6819817_0 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 594.0
WH2_k127_6819817_1 Flagellar biosynthetic protein FliR K02421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 426.0
WH2_k127_6819817_2 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000001482 207.0
WH2_k127_6819817_3 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000009229 159.0
WH2_k127_6819817_4 Bacterial export proteins, family 3 - - - 0.0000000000000000000000000000000002651 139.0
WH2_k127_6824514_0 YjgP YjgQ family K11720 - - 6.953e-201 629.0
WH2_k127_6824514_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 312.0
WH2_k127_6824514_2 YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000001308 147.0
WH2_k127_6824514_3 Fatty acid desaturase - - - 0.00000000000000000000000000003587 116.0
WH2_k127_6874170_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 567.0
WH2_k127_6874170_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 414.0
WH2_k127_6874170_2 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 353.0
WH2_k127_6874170_3 - - - - 0.0000000000000000000000000000000000000000000000000000202 203.0
WH2_k127_6874170_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000043 180.0
WH2_k127_6874170_5 transcriptional K13639 - - 0.0000000000000000000000000000003428 124.0
WH2_k127_6874170_6 glutamate--cysteine ligase K01919 - 6.3.2.2 0.00000008421 55.0
WH2_k127_6920836_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.329e-271 838.0
WH2_k127_6920836_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 1.165e-240 751.0
WH2_k127_6920836_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 8.399e-240 743.0
WH2_k127_6920836_3 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 419.0
WH2_k127_6920836_4 OmpW family K07275 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 406.0
WH2_k127_6920836_5 OmpW family K07275 - - 0.0005621 42.0
WH2_k127_6941609_0 Amidase K01457 - 3.5.1.54 0.0 1030.0
WH2_k127_6941609_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 424.0
WH2_k127_6941609_2 Allophanate hydrolase subunit 2 K01941 - 6.3.4.6 0.00000002225 55.0
WH2_k127_6961097_0 receptor - - - 0.0 1234.0
WH2_k127_6961097_1 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 456.0
WH2_k127_6984557_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 487.0
WH2_k127_6984557_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007879 271.0
WH2_k127_7015742_0 phosphate transport system permease K02038 - - 3.298e-237 737.0
WH2_k127_7015742_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 4.776e-196 614.0
WH2_k127_7015742_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 518.0
WH2_k127_7015742_3 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000001371 187.0
WH2_k127_7034750_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 377.0
WH2_k127_7034750_1 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000000000000000000000000001759 216.0
WH2_k127_7034750_2 - - - - 0.00000000000000000000000000000000000000000002961 165.0
WH2_k127_7034750_3 COG1278 Cold shock proteins - - - 0.00000000000000000000000000000000002921 138.0
WH2_k127_7034750_4 Ion channel - - - 0.000000000000000000000000000000004283 136.0
WH2_k127_7034750_5 - - - - 0.00000000000000005269 81.0
WH2_k127_7034750_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000002171 76.0
WH2_k127_7043523_0 Glycine cleavage system T protein K00605 - 2.1.2.10 5.776e-223 701.0
WH2_k127_7043523_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 418.0
WH2_k127_7043523_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 329.0
WH2_k127_7043523_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000001329 210.0
WH2_k127_7043523_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000001878 192.0
WH2_k127_7068934_0 glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1531.0
WH2_k127_7068934_1 Reductase C-terminal K00529 - 1.18.1.3 4.282e-241 749.0
WH2_k127_7068934_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 5.209e-194 608.0
WH2_k127_7068934_3 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 598.0
WH2_k127_7068934_4 ABC-type Na efflux pump, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 320.0
WH2_k127_7095288_0 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 2.527e-245 783.0
WH2_k127_7095288_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 2.595e-194 623.0
WH2_k127_7095288_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 512.0
WH2_k127_7095288_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 371.0
WH2_k127_7095288_4 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 301.0
WH2_k127_7095288_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000004147 124.0
WH2_k127_7095288_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000003538 66.0
WH2_k127_7095288_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000001059 64.0
WH2_k127_7113575_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 595.0
WH2_k127_7113575_1 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 447.0
WH2_k127_7113575_2 Dicarboxylate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 421.0
WH2_k127_7136344_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.135e-317 976.0
WH2_k127_7136344_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 557.0
WH2_k127_7136344_2 DNA polymerase K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 532.0
WH2_k127_7136344_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 324.0
WH2_k127_7136344_4 LuxR family transcriptional regulator K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000001128 232.0
WH2_k127_7136344_5 Lytic murein transglycosylase - - - 0.0000000000000000000000000000000000004774 139.0
WH2_k127_713791_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 8.784e-275 848.0
WH2_k127_713791_1 Cytochrome c1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 519.0
WH2_k127_713791_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 391.0
WH2_k127_713791_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 340.0
WH2_k127_713791_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 337.0
WH2_k127_713791_5 Domain related to MnhB subunit of Na+/H+ antiporter K05559 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 296.0
WH2_k127_713791_6 aminopeptidase N K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000003652 166.0
WH2_k127_7142335_0 RNA polymerase sigma K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 539.0
WH2_k127_7142335_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 542.0
WH2_k127_7142335_2 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 451.0
WH2_k127_7142335_3 Histidine phosphotransferase C-terminal domain K13588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 392.0
WH2_k127_7142335_4 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 388.0
WH2_k127_7142335_6 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000000000000000000000000000000000000000005105 188.0
WH2_k127_7142335_7 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000006028 96.0
WH2_k127_7142335_8 - - - - 0.000000001887 62.0
WH2_k127_7145955_0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 1.688e-279 864.0
WH2_k127_7145955_1 NAD(P) transhydrogenase subunit alpha K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 431.0
WH2_k127_7145955_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 404.0
WH2_k127_7145955_3 PhoD-like phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 281.0
WH2_k127_7145955_4 - - - - 0.0000000000000000000000000000002982 128.0
WH2_k127_7160272_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1295.0
WH2_k127_7160272_1 thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 352.0
WH2_k127_7160272_2 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 313.0
WH2_k127_7160272_3 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004501 259.0
WH2_k127_7160272_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002613 244.0
WH2_k127_7192606_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 601.0
WH2_k127_7192606_1 Belongs to the 'phage' integrase family K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 497.0
WH2_k127_7192606_2 membrane-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 380.0
WH2_k127_7192606_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 348.0
WH2_k127_7192606_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000005328 242.0
WH2_k127_7192606_5 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000000000000000000002906 183.0
WH2_k127_7197592_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.286e-207 647.0
WH2_k127_7197592_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 482.0
WH2_k127_7197592_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 462.0
WH2_k127_7197592_3 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 376.0
WH2_k127_72059_0 Dienelactone hydrolase family - - - 0.0 1116.0
WH2_k127_72059_1 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase K06147 - - 0.0 1018.0
WH2_k127_72059_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.761e-247 767.0
WH2_k127_72059_3 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006102 276.0
WH2_k127_72059_4 ACT domain K09964 - - 0.000000000000000000000000000000000000000000000000000005075 193.0
WH2_k127_72059_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000001261 154.0
WH2_k127_72059_6 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000002526 82.0
WH2_k127_7217667_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 588.0
WH2_k127_7217667_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 456.0
WH2_k127_7217667_2 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000721 225.0
WH2_k127_732155_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 451.0
WH2_k127_732155_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 306.0
WH2_k127_732155_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001833 258.0
WH2_k127_732155_3 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.00000000009308 61.0
WH2_k127_7339970_0 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 518.0
WH2_k127_7339970_1 SufE protein probably involved in Fe-S center assembly K02426 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008199 238.0
WH2_k127_7339970_2 - - - - 0.0000000000000000000000000000000000000000000000004755 175.0
WH2_k127_7339970_3 - - - - 0.0000000000000000000000000000002201 128.0
WH2_k127_7339970_4 - - - - 0.000000000000000000000000003264 117.0
WH2_k127_7339970_5 - - - - 0.00000000000000000000000006623 115.0
WH2_k127_7339970_6 - - - - 0.00000000000000000000001575 102.0
WH2_k127_7375409_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 6.465e-220 684.0
WH2_k127_7375409_1 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 450.0
WH2_k127_7375409_2 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 398.0
WH2_k127_7405896_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.0 1120.0
WH2_k127_7405896_1 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 3.795e-233 725.0
WH2_k127_7405896_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 8.888e-202 630.0
WH2_k127_7405896_3 Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 509.0
WH2_k127_7405896_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 366.0
WH2_k127_7405896_5 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002293 275.0
WH2_k127_7405896_6 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000000000000000000000000002155 231.0
WH2_k127_7405896_7 - - - - 0.0000000000000000000000000000000000000000000000002601 181.0
WH2_k127_7405896_8 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000002204 145.0
WH2_k127_7406694_0 Dicarboxylate transport - - - 3.754e-201 632.0
WH2_k127_7406694_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 530.0
WH2_k127_7406694_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 479.0
WH2_k127_7406694_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 473.0
WH2_k127_7406694_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000000008071 231.0
WH2_k127_7406694_5 protein conserved in bacteria K09978 - - 0.00000000000000000000000000000000000000000000000000000000000000001557 225.0
WH2_k127_7406694_6 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000000000000000000000000000000000000000000000001409 182.0
WH2_k127_7406694_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000003266 149.0
WH2_k127_7406694_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000007973 131.0
WH2_k127_7406694_9 YnbE-like lipoprotein - - - 0.0000000000000000000000101 104.0
WH2_k127_7442497_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.039e-288 889.0
WH2_k127_7442497_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.345e-275 846.0
WH2_k127_7442497_2 Histidine kinase - - - 9.43e-228 712.0
WH2_k127_7442497_3 membrane metal-binding protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 514.0
WH2_k127_7442497_5 Protein conserved in bacteria - - - 0.0000000001664 63.0
WH2_k127_7464126_0 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 410.0
WH2_k127_7464126_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 334.0
WH2_k127_7464126_2 Ubiquinol-cytochrome C chaperone K17662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 304.0
WH2_k127_7464126_3 Small protein A (tmRNA-binding) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001405 263.0
WH2_k127_7464126_4 Uncharacterized ACR, COG1399 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002775 249.0
WH2_k127_7464126_5 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000000000000000000000004988 144.0
WH2_k127_7484869_0 Polynucleotide adenylyltransferase K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 433.0
WH2_k127_7484869_1 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 291.0
WH2_k127_7484869_2 protein conserved in bacteria K09986 - - 0.0000000000000000000000000000000000000000000000000000000000000002624 221.0
WH2_k127_748911_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 4.694e-282 874.0
WH2_k127_748911_1 cytochrome P450 - - - 2.187e-270 835.0
WH2_k127_748911_2 ABC-type Na efflux pump, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 406.0
WH2_k127_748911_3 PilZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 347.0
WH2_k127_748911_4 conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 297.0
WH2_k127_748911_5 Transcriptional regulator K07979 - - 0.00000000000000000000000000000000000000000000000000000000003665 207.0
WH2_k127_748911_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000000007055 167.0
WH2_k127_7530779_0 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 601.0
WH2_k127_7530779_1 Enoyl-(Acyl carrier protein) reductase K14189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 388.0
WH2_k127_7530779_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000001457 236.0
WH2_k127_7531632_0 DNA-binding protein with the helix-hairpin-helix motif - - - 2.388e-249 775.0
WH2_k127_7531632_1 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 527.0
WH2_k127_7531632_2 - - - - 0.0000000000000000000000006011 113.0
WH2_k127_7553706_0 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 1.366e-238 739.0
WH2_k127_7553706_1 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 597.0
WH2_k127_7553706_2 PhoD-like phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 493.0
WH2_k127_7553706_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 348.0
WH2_k127_7553706_4 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000006907 190.0
WH2_k127_7571351_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1414.0
WH2_k127_7571351_1 Circularly permuted ATP-grasp type 2 - - - 2.325e-297 914.0
WH2_k127_7571351_2 peptidase S10 serine carboxypeptidase - - - 1.122e-284 878.0
WH2_k127_7571351_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 451.0
WH2_k127_7571351_4 Thiol disulfide interchange protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 302.0
WH2_k127_7571351_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002198 244.0
WH2_k127_7571351_6 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004389 248.0
WH2_k127_7571351_7 protein conserved in bacteria - - - 0.00000000000000000000000173 102.0
WH2_k127_7577713_0 ABC-type Fe3 transport system, permease component K02011 - - 3.14e-271 844.0
WH2_k127_7577713_1 Magnesium chelatase, subunit ChlI K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 599.0
WH2_k127_7577713_2 ABC transporter, ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 482.0
WH2_k127_7577713_3 von Willebrand factor type A domain K03404 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000003458 193.0
WH2_k127_7593007_0 Transport of potassium into the cell K03549 - - 0.0 1012.0
WH2_k127_7593007_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 570.0
WH2_k127_7593007_2 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 397.0
WH2_k127_7593007_3 2-methylthioadenine K18707 - 2.8.4.5 0.0000000000000000000000000000000001718 133.0
WH2_k127_760219_0 Belongs to the GSP D family K02280 - - 4.784e-302 933.0
WH2_k127_760219_1 Flp pilus assembly protein, ATPase CpaE K02282 - - 7.533e-256 791.0
WH2_k127_760219_10 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000007988 234.0
WH2_k127_760219_2 type II secretion system protein K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 548.0
WH2_k127_760219_3 pilus assembly protein TadB K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 543.0
WH2_k127_760219_4 Pilus assembly protein CpaB K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 520.0
WH2_k127_760219_5 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 512.0
WH2_k127_760219_6 Lysophospholipase K01048 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 512.0
WH2_k127_760219_7 Pilus assembly protein CpaD K02281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 372.0
WH2_k127_760219_8 Oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 338.0
WH2_k127_760219_9 peptidase K02278 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
WH2_k127_7628015_0 Belongs to the glycosyl hydrolase 13 family K02438 - 3.2.1.196 4.13e-293 909.0
WH2_k127_7628015_1 Phosphoglucomutase K01835 - 5.4.2.2 4.075e-281 871.0
WH2_k127_7628015_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.603e-218 686.0
WH2_k127_7628015_3 receptor - - - 0.000000000000000000000000000000000000000000000000000000003976 199.0
WH2_k127_7659162_0 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 4.575e-237 735.0
WH2_k127_7659162_1 Bacterial PH domain - - - 3.877e-226 713.0
WH2_k127_7659162_2 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 593.0
WH2_k127_7659162_3 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 458.0
WH2_k127_7659162_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 454.0
WH2_k127_7659162_5 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 431.0
WH2_k127_7659162_6 Bacterial PH domain K09167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000349 275.0
WH2_k127_7659162_7 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003331 260.0
WH2_k127_7659162_8 acetyltransferase K06975 - - 0.000001247 56.0
WH2_k127_7668282_0 Histidine kinase - - - 1.328e-225 706.0
WH2_k127_7668282_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 366.0
WH2_k127_7668282_2 - - - - 0.0000000000000000000000004376 109.0
WH2_k127_7668282_3 Urate oxidase N-terminal - - - 0.00000000000000000000004013 99.0
WH2_k127_7677111_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 9.309e-202 633.0
WH2_k127_7677111_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 307.0
WH2_k127_7677111_2 COG0463 Glycosyltransferases involved in cell wall biogenesis K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000176 174.0
WH2_k127_7677111_3 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000000000000000001722 141.0
WH2_k127_7677111_4 Membrane fusogenic activity K09806 - - 0.000000000000000000000000000000000004536 141.0
WH2_k127_7707277_0 Metal-dependent hydrolase - - - 8.056e-315 974.0
WH2_k127_7707277_1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 506.0
WH2_k127_7707277_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 455.0
WH2_k127_7707277_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000000000000000000001265 166.0
WH2_k127_7757271_0 protein-S-isoprenylcysteine methyltransferase - - - 4.202e-257 797.0
WH2_k127_7757271_1 Pyrrolo-quinoline quinone - - - 4.223e-257 798.0
WH2_k127_7757271_2 CHAT domain - - - 5.877e-200 638.0
WH2_k127_7757271_3 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 598.0
WH2_k127_7757271_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 506.0
WH2_k127_7757271_5 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 397.0
WH2_k127_7757271_6 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 393.0
WH2_k127_7757271_7 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 327.0
WH2_k127_7757271_8 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000004539 168.0
WH2_k127_7760508_0 Transketolase, thiamine diphosphate binding domain K00163 - 1.2.4.1 1.247e-194 611.0
WH2_k127_7760508_1 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 440.0
WH2_k127_7760508_2 Mo-molybdopterin cofactor biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 371.0
WH2_k127_7760508_3 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000143 273.0
WH2_k127_7760508_4 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.000000000000000000000000000000000000000000005257 174.0
WH2_k127_7760508_5 alpha beta - - - 0.0000000000000000000000000000000000000001693 168.0
WH2_k127_7760508_7 AntiSigma factor - - - 0.000000000000000000000000000109 127.0
WH2_k127_7760508_8 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000003105 117.0
WH2_k127_7760508_9 (ABC) transporter K06147 - - 0.00000000000000000000002599 112.0
WH2_k127_7777031_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0 1057.0
WH2_k127_7777031_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1032.0
WH2_k127_7777031_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 556.0
WH2_k127_7779695_0 alcohol dehydrogenase - - - 4.51e-208 648.0
WH2_k127_7779695_1 Molydopterin dinucleotide binding domain - - - 1.184e-195 611.0
WH2_k127_7779695_2 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000001236 164.0
WH2_k127_7786379_0 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 6.87e-223 696.0
WH2_k127_7786379_1 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 546.0
WH2_k127_7786379_2 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 531.0
WH2_k127_7786379_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 460.0
WH2_k127_7786379_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 402.0
WH2_k127_7786379_5 Carbohydrate-selective porin, OprB family K07267 - - 0.00000000000000000000000000000000000001784 151.0
WH2_k127_7788202_0 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 1.351e-210 665.0
WH2_k127_7788202_1 Peptidyl-prolyl cis-trans - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 346.0
WH2_k127_7788202_2 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 320.0
WH2_k127_7788202_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000001354 185.0
WH2_k127_7788202_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000002773 179.0
WH2_k127_7788202_5 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000002051 117.0
WH2_k127_7788202_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000003061 108.0
WH2_k127_7806734_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 516.0
WH2_k127_7806734_1 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009843 266.0
WH2_k127_7806734_2 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000000000000000000000000000000000000002977 224.0
WH2_k127_7811374_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.464e-265 822.0
WH2_k127_7811374_1 Protein of unknown function (DUF3376) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 548.0
WH2_k127_7811374_2 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000000000000005364 218.0
WH2_k127_7828000_0 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 1.812e-265 820.0
WH2_k127_7828000_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 5.892e-195 610.0
WH2_k127_7828000_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.000000000000004737 76.0
WH2_k127_7828000_3 PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 0.0003405 46.0
WH2_k127_7832659_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 6.734e-295 907.0
WH2_k127_7832659_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.924e-240 745.0
WH2_k127_7832659_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001958 233.0
WH2_k127_7832659_11 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000000000001663 222.0
WH2_k127_7832659_12 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000000000000000000006577 206.0
WH2_k127_7832659_13 - - - - 0.000000000000000000000000000000000000000000000000000000000883 205.0
WH2_k127_7832659_14 protein conserved in bacteria K09948 - - 0.00000000000000000000000000000000000000000000000000003693 188.0
WH2_k127_7832659_15 Belongs to the UPF0335 family - - - 0.00000000000000000000000000000000000000007155 153.0
WH2_k127_7832659_16 Peptidase inhibitor I78 family - - - 0.000000000000000000000000000000000006597 138.0
WH2_k127_7832659_17 O-Antigen ligase - - - 0.00000008421 55.0
WH2_k127_7832659_18 - - - - 0.0009165 42.0
WH2_k127_7832659_2 enoyl-CoA hydratase K01692 - 4.2.1.17 1.082e-218 680.0
WH2_k127_7832659_3 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 507.0
WH2_k127_7832659_4 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 488.0
WH2_k127_7832659_5 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 333.0
WH2_k127_7832659_6 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 323.0
WH2_k127_7832659_7 Protein of unknown function (DUF1214) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 306.0
WH2_k127_7832659_8 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 288.0
WH2_k127_7832659_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000427 271.0
WH2_k127_7868756_0 ATP-dependent DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.906e-311 958.0
WH2_k127_7868756_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 522.0
WH2_k127_7868756_2 Protein of unknown function (DUF1275) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 335.0
WH2_k127_7868756_3 Domain of unknown function (DUF1993) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008228 269.0
WH2_k127_7868756_4 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000005524 235.0
WH2_k127_7868756_5 - - - - 0.000000000000000000000000000000000006962 143.0
WH2_k127_7868756_6 DUF167 - - - 0.00000000000000000000000008409 112.0
WH2_k127_7869054_0 DNA helicase K03654 - 3.6.4.12 2.425e-239 743.0
WH2_k127_7869054_1 - K03832 - - 0.000000000000000000000000000000000000000000000000000000000000003091 218.0
WH2_k127_7871765_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 5.633e-312 959.0
WH2_k127_7871765_1 Major Facilitator - - - 1.358e-307 948.0
WH2_k127_7871765_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 543.0
WH2_k127_7871765_3 synthesis repressor PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 331.0
WH2_k127_7871765_4 NifU homolog involved in Fe-S cluster formation - - - 0.0000000000000000000000000000000000000000000000000004373 190.0
WH2_k127_7871765_5 Colicin V production protein K03558 - - 0.00000000000000000000000000001764 122.0
WH2_k127_7871765_6 Peptidase, M28 - - - 0.00000000000004069 74.0
WH2_k127_7875934_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1537.0
WH2_k127_7875934_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 304.0
WH2_k127_7875934_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002228 247.0
WH2_k127_7875934_3 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000004254 197.0
WH2_k127_7886269_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.955e-292 899.0
WH2_k127_7886269_1 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 502.0
WH2_k127_7886269_2 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 399.0
WH2_k127_7886269_3 protein conserved in bacteria - - - 0.0000000000000000000000006275 104.0
WH2_k127_7886462_0 Cytochrome c554 and c-prime - - - 9.613e-264 816.0
WH2_k127_7886462_1 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 535.0
WH2_k127_7886462_2 - - - - 0.000000000000000000000000000000000000000000000000007818 181.0
WH2_k127_7981481_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.0 1093.0
WH2_k127_7981481_1 Transketolase, thiamine diphosphate binding domain K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 485.0
WH2_k127_7981481_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 419.0
WH2_k127_7981481_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 316.0
WH2_k127_7981481_4 MAPEG family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001067 239.0
WH2_k127_7985116_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 2.356e-230 721.0
WH2_k127_7985116_1 Alkaline phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008263 279.0
WH2_k127_8033385_0 flagellar hook-associated protein K02396 - - 1.06e-220 691.0
WH2_k127_8033385_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 413.0
WH2_k127_8033385_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 286.0
WH2_k127_8033385_3 Rod binding protein K02395 - - 0.000000000000000000000000000000000000000006581 158.0
WH2_k127_8046115_0 Dehydratase family K22216 - - 1.553e-272 848.0
WH2_k127_8046115_1 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 374.0
WH2_k127_8046115_2 reductase K22185 - 1.1.1.175 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 353.0
WH2_k127_8046115_3 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001647 252.0
WH2_k127_8046115_4 Aldolase K01631 - 4.1.2.21 0.0000000000000000000000000002863 115.0
WH2_k127_8051325_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 524.0
WH2_k127_8051325_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 414.0
WH2_k127_8051325_2 Adenylate kinase and related kinases - - - 0.0000000000000000000001689 97.0
WH2_k127_809845_0 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000718 452.0
WH2_k127_809845_1 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 387.0
WH2_k127_809845_2 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 286.0
WH2_k127_809845_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009999 275.0
WH2_k127_809845_4 Peptidase M50B-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003322 270.0
WH2_k127_809845_5 - - - - 0.000000001639 58.0
WH2_k127_8110894_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 1021.0
WH2_k127_8110894_1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 1.252e-273 845.0
WH2_k127_8110894_2 sugar transferase - - - 5.928e-271 837.0
WH2_k127_8110894_3 Transcriptional regulator K07110 - - 5.943e-263 812.0
WH2_k127_8110894_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 290.0
WH2_k127_8110894_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000446 231.0
WH2_k127_8116071_0 COG2366 Protein related to penicillin acylase K07116 - 3.5.1.97 0.0 1046.0
WH2_k127_8116071_1 Peptidase, M16 - - - 0.0002103 45.0
WH2_k127_8123377_0 amidohydrolase - - - 3.502e-248 770.0
WH2_k127_8123377_1 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 535.0
WH2_k127_8123377_2 Isocitrate lyase K01637 - 4.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 493.0
WH2_k127_8123377_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 367.0
WH2_k127_8123377_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000009813 180.0
WH2_k127_8123377_5 - - - - 0.000000000000000000000000000286 114.0
WH2_k127_8123377_6 Resolvase - - - 0.0000000005811 60.0
WH2_k127_817587_0 Belongs to the thiolase family K00626 - 2.3.1.9 3.126e-243 754.0
WH2_k127_817587_1 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 6.725e-198 617.0
WH2_k127_817587_2 carnitine dehydratase K14470 - 5.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 524.0
WH2_k127_817587_3 peptidase M13 K07386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 469.0
WH2_k127_817587_4 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 469.0
WH2_k127_817587_5 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 466.0
WH2_k127_817587_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 447.0
WH2_k127_817587_7 - - - - 0.000000000000000000000000000002555 122.0
WH2_k127_817729_0 ATPase with chaperone activity K07391 - - 1.767e-255 790.0
WH2_k127_817729_1 - K03832 - - 0.0000000000000000000000000000000000000000000000000000005308 198.0
WH2_k127_8211023_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 9.459e-294 903.0
WH2_k127_8211023_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001081 270.0
WH2_k127_8211023_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000654 123.0
WH2_k127_8211023_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000003749 98.0
WH2_k127_8211307_0 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 341.0
WH2_k127_8211307_1 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 311.0
WH2_k127_8211307_2 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 286.0
WH2_k127_8211307_3 - - - - 0.000000000000000000000000000000000000000000000000000000008811 202.0
WH2_k127_8248006_0 TonB dependent receptor - - - 0.0 1444.0
WH2_k127_8248006_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 382.0
WH2_k127_8248006_2 - - - - 0.0000000000000000000000000000000000000000000000000003309 192.0
WH2_k127_826483_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 8.167e-297 917.0
WH2_k127_826483_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 415.0
WH2_k127_826883_0 phosphomannomutase K01840 - 5.4.2.8 1.521e-287 887.0
WH2_k127_826883_1 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 518.0
WH2_k127_826883_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 423.0
WH2_k127_826883_3 Heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000002169 156.0
WH2_k127_826883_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000002773 146.0
WH2_k127_826883_5 helicase K03724 - - 0.0000000000005744 72.0
WH2_k127_827400_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.367e-210 658.0
WH2_k127_827400_1 IV secretion system protein K03196 - - 3.583e-196 616.0
WH2_k127_827400_2 Bacterial conjugation TrbI-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 546.0
WH2_k127_827400_3 TrbL/VirB6 plasmid conjugal transfer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 500.0
WH2_k127_827400_4 Conjugal transfer protein K03204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 428.0
WH2_k127_8323845_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 587.0
WH2_k127_8323845_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 461.0
WH2_k127_8323845_2 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 349.0
WH2_k127_8335962_0 nucleoside K03317 - - 8.321e-229 713.0
WH2_k127_8335962_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 488.0
WH2_k127_8335962_2 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.00000000000000000000000000000000000001993 145.0
WH2_k127_8335962_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000001722 126.0
WH2_k127_8335962_4 - - - - 0.000000000000000000000000000002261 135.0
WH2_k127_8387841_0 homoserine dehydrogenase K00003 - 1.1.1.3 1.267e-250 777.0
WH2_k127_8387841_1 helicase K03724 - - 5.721e-249 769.0
WH2_k127_8387841_10 - - - - 0.00000000000000000004652 96.0
WH2_k127_8387841_2 in Escherichia coli this protein forms a dimer and binds manganese K11532 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 606.0
WH2_k127_8387841_3 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 439.0
WH2_k127_8387841_4 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 413.0
WH2_k127_8387841_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 410.0
WH2_k127_8387841_6 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 335.0
WH2_k127_8387841_7 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 294.0
WH2_k127_8387841_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 291.0
WH2_k127_8387841_9 Biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008008 247.0
WH2_k127_841776_0 ABC-type oligopeptide transport system, periplasmic component K02035,K15580 - - 1.735e-236 740.0
WH2_k127_841776_1 protein conserved in bacteria K09919 - - 4.858e-234 726.0
WH2_k127_841776_10 Protein of unknown function (DUF3572) - - - 0.00000000000000000000000000005574 124.0
WH2_k127_841776_11 acyl carrier protein - - - 0.00000000000000000000004769 100.0
WH2_k127_841776_12 Domain of unknown function (DUF4112) - - - 0.000000000002002 70.0
WH2_k127_841776_2 glycerophosphoryl diester phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 422.0
WH2_k127_841776_3 UMP catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 410.0
WH2_k127_841776_4 mRNA catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 310.0
WH2_k127_841776_5 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 292.0
WH2_k127_841776_6 endoribonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002125 271.0
WH2_k127_841776_7 response regulator K11443 - - 0.000000000000000000000000000000000000000000000000000000000004782 209.0
WH2_k127_841776_8 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000008192 164.0
WH2_k127_841776_9 PilZ domain - - - 0.00000000000000000000000000000000000000001087 155.0
WH2_k127_8504071_0 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 371.0
WH2_k127_8504071_1 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000553 286.0
WH2_k127_8504071_2 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000005929 229.0
WH2_k127_8504071_3 Hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000006938 214.0
WH2_k127_8504071_4 - - - - 0.0000000000000000000001437 105.0
WH2_k127_8531072_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1116.0
WH2_k127_8531072_1 Flp pilus assembly protein, ATPase CpaF K02283 - - 1.146e-292 901.0
WH2_k127_8531072_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003339 279.0
WH2_k127_8548852_0 Peptidase M48 - - - 1.105e-253 788.0
WH2_k127_8548852_1 PAS domain - - - 3.393e-248 778.0
WH2_k127_8548852_2 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 520.0
WH2_k127_8548852_3 sterol desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 494.0
WH2_k127_8548852_4 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 340.0
WH2_k127_8548852_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 284.0
WH2_k127_8548852_6 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.000000000000000000000000000000000000000000000000000000000000000000005795 245.0
WH2_k127_8548852_7 DNA repair protein MmcB-like - - - 0.000000000000000000000000000000000003837 137.0
WH2_k127_8627170_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 4.028e-210 657.0
WH2_k127_8627170_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 346.0
WH2_k127_8627170_2 - - - - 0.000000000000000000000000000000000000000000000003621 179.0
WH2_k127_8688284_0 receptor K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 488.0
WH2_k127_8688284_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 429.0
WH2_k127_869516_0 N-terminal domain of oxidoreductase K07119 - - 3.293e-194 608.0
WH2_k127_869516_1 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 387.0
WH2_k127_869516_2 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 358.0
WH2_k127_869516_3 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005947 244.0
WH2_k127_8705819_0 Protein of unknown function (DUF3089) - - - 2.003e-225 700.0
WH2_k127_8705819_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 529.0
WH2_k127_8705819_2 pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 421.0
WH2_k127_8705819_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 301.0
WH2_k127_8705819_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 293.0
WH2_k127_8705819_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001025 254.0
WH2_k127_8705819_6 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000001317 210.0
WH2_k127_8705819_7 - - - - 0.000000000000000000000000000000001532 134.0
WH2_k127_8732033_0 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 599.0
WH2_k127_8732033_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
WH2_k127_8732033_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000785 232.0
WH2_k127_8732033_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000002394 208.0
WH2_k127_873292_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 1.621e-208 653.0
WH2_k127_873292_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 286.0
WH2_k127_873292_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000001207 257.0
WH2_k127_873292_3 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001255 251.0
WH2_k127_873292_4 PFAM Alpha beta hydrolase fold-3 domain protein - - - 0.000000000000000000000000000000000000000001178 156.0
WH2_k127_8846230_0 methyl-accepting chemotaxis protein K03406 - - 1.015e-202 634.0
WH2_k127_8846230_1 ATPase AAA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 567.0
WH2_k127_8846230_2 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 560.0
WH2_k127_8846230_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
WH2_k127_8846230_4 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000473 105.0
WH2_k127_8861222_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 9.621e-214 673.0
WH2_k127_8861222_1 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 342.0
WH2_k127_8916449_0 Metallopeptidase family M24 - - - 4.813e-250 794.0
WH2_k127_8916449_1 endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 355.0
WH2_k127_8916449_2 Methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 305.0
WH2_k127_8916449_3 translation initiation inhibitor, yjgF family - - - 0.000003068 51.0
WH2_k127_8924810_0 Belongs to the DEAD box helicase family - - - 3.647e-265 822.0
WH2_k127_8924810_1 FAD linked - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 372.0
WH2_k127_8924810_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003237 274.0
WH2_k127_8945376_0 dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 5.153e-228 709.0
WH2_k127_8945376_1 aspartate racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 413.0
WH2_k127_8945376_2 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 396.0
WH2_k127_8945376_3 Domain of unknown function (DUF4281) - - - 0.000000000000000001995 86.0
WH2_k127_89456_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 2.665e-298 917.0
WH2_k127_89456_1 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 581.0
WH2_k127_89456_10 AMP-binding enzyme C-terminal domain - - - 0.000000000003314 66.0
WH2_k127_89456_2 protein conserved in bacteria K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 499.0
WH2_k127_89456_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 443.0
WH2_k127_89456_4 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 393.0
WH2_k127_89456_5 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 340.0
WH2_k127_89456_6 Ribosomal protein S6 modification protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006302 272.0
WH2_k127_89456_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000000000004495 227.0
WH2_k127_89456_8 - - - - 0.0000000000000000000000000000000000000000000000007205 181.0
WH2_k127_89456_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000006821 145.0
WH2_k127_8945931_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1674.0
WH2_k127_8945931_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 7.368e-288 888.0
WH2_k127_8945931_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 516.0
WH2_k127_8945931_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 369.0
WH2_k127_8945931_4 YhhN family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 347.0
WH2_k127_8945931_5 EF hand - - - 0.0000000000000000000000000000000000000000000000000000000000000000005358 231.0
WH2_k127_895910_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1427.0
WH2_k127_895910_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008062 260.0
WH2_k127_895910_2 peptidyl-tyrosine sulfation - - - 0.0002252 54.0
WH2_k127_8964220_0 Molydopterin dinucleotide binding domain - - - 2.623e-257 796.0
WH2_k127_8964220_1 N-terminal domain of oxidoreductase K07119 - - 9.427e-209 650.0
WH2_k127_8964220_2 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 488.0
WH2_k127_8964220_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 481.0
WH2_k127_8964220_4 FAD binding domain K05898 - 1.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 302.0
WH2_k127_8964220_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 293.0
WH2_k127_8964220_6 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003283 266.0
WH2_k127_8964220_7 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000006829 94.0
WH2_k127_8989420_0 dehydratase K07749 - 2.8.3.16 3.323e-244 755.0
WH2_k127_8989420_1 Isochorismatase family K13995 - 3.5.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 368.0
WH2_k127_8989420_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 303.0
WH2_k127_9003335_0 - - - - 1.18e-309 963.0
WH2_k127_9003335_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 1.46e-197 619.0
WH2_k127_9003335_2 acetyl propionyl-CoA carboxylase, alpha subunit K01965 - 6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 553.0
WH2_k127_9003335_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 550.0
WH2_k127_9003335_4 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 497.0
WH2_k127_9003335_5 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 492.0
WH2_k127_9003335_6 Acetyltransferase (GNAT) family K03829 - - 0.0000000000000000000000000000000000000000000000000000000000000000004897 233.0
WH2_k127_9003335_7 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000002026 204.0
WH2_k127_9003335_8 - - - - 0.0000000000000000000000000000000000000002376 153.0
WH2_k127_9009890_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 6.586e-222 690.0
WH2_k127_9009890_1 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 411.0
WH2_k127_9009890_2 with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000147 219.0
WH2_k127_9015024_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1308.0
WH2_k127_9015024_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 5.446e-277 862.0
WH2_k127_9015024_10 Uncharacterized protein conserved in bacteria (DUF2256) - - - 0.000000000000000000000001916 102.0
WH2_k127_9015024_2 peptidylprolyl isomerase K03771 - 5.2.1.8 1.051e-224 703.0
WH2_k127_9015024_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 557.0
WH2_k127_9015024_4 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 365.0
WH2_k127_9015024_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002542 273.0
WH2_k127_9015024_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002048 238.0
WH2_k127_9015024_7 DNA polymerase III K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000181 234.0
WH2_k127_9015024_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000004389 123.0
WH2_k127_9015024_9 - - - - 0.0000000000000000000000005813 108.0
WH2_k127_9015289_0 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 522.0
WH2_k127_9015289_1 Peptidase S41 K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 449.0
WH2_k127_9015289_2 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000001849 115.0
WH2_k127_9036085_0 Sugar transporter K16211 - - 3.759e-221 691.0
WH2_k127_9036085_1 receptor - - - 3.4e-209 652.0
WH2_k127_9036085_2 receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 384.0
WH2_k127_9074564_0 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 607.0
WH2_k127_9074564_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008256 368.0
WH2_k127_9081845_0 Glycosyl transferase - - - 5.392e-236 737.0
WH2_k127_9081845_1 - - - - 0.000000000000000000000000000989 118.0
WH2_k127_9081845_2 - - - - 0.0000000000000000001047 93.0
WH2_k127_9081845_3 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.00000007973 53.0
WH2_k127_9116790_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 5.358e-301 927.0
WH2_k127_9116790_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 557.0
WH2_k127_9116790_2 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004114 272.0
WH2_k127_9116790_3 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000000000000000000000000000000002123 201.0
WH2_k127_911686_0 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 551.0
WH2_k127_911686_1 lipid kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 351.0
WH2_k127_911686_2 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 335.0
WH2_k127_9147340_0 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 458.0
WH2_k127_9147340_1 Retinal pigment epithelial membrane protein K11159,K21822 - 1.13.11.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007149 266.0
WH2_k127_9147340_2 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000358 163.0
WH2_k127_9184806_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.41e-269 831.0
WH2_k127_9184806_1 NADH dehydrogenase K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 452.0
WH2_k127_9184806_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 445.0
WH2_k127_9184806_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009648 394.0
WH2_k127_9184806_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 262.0
WH2_k127_9219879_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0 1015.0
WH2_k127_9219879_1 Na -driven multidrug efflux pump K03327 - - 2.745e-245 765.0
WH2_k127_9219879_2 COG0668 Small-conductance mechanosensitive channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 398.0
WH2_k127_9219879_3 - - - - 0.000000000000000000000000000000000000000000000000000016 208.0
WH2_k127_9219879_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000005012 181.0
WH2_k127_9219879_5 - - - - 0.00000007973 53.0
WH2_k127_9245035_0 Enoyl-CoA hydratase/isomerase - - - 0.0 1709.0
WH2_k127_9247051_0 Alkyl sulfatase dimerisation - - - 0.0 1044.0
WH2_k127_9247051_1 Protein of unknown function (DUF1800) - - - 3.399e-234 731.0
WH2_k127_9247051_2 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 421.0
WH2_k127_9262533_0 Cytochrome p450 - - - 7.897e-235 727.0
WH2_k127_9262533_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 9.319e-207 649.0
WH2_k127_9262533_2 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 0.0000000000000000000008969 94.0
WH2_k127_9286191_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 497.0
WH2_k127_9286191_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 465.0
WH2_k127_9286191_2 COG0332 3-oxoacyl- acyl-carrier-protein synthase III K16872 - 2.3.1.207 0.00000000000000000000000000000000000002461 143.0
WH2_k127_9292657_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 4.033e-265 819.0
WH2_k127_9292657_1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis K11740 - - 1.476e-255 794.0
WH2_k127_9292657_2 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 445.0
WH2_k127_9292657_3 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 407.0
WH2_k127_9292657_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 380.0
WH2_k127_9292657_5 COG0346 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001042 278.0
WH2_k127_9292657_6 - - - - 0.00000000000000005735 92.0
WH2_k127_929554_0 membrane - - - 2.158e-317 979.0
WH2_k127_929554_1 Belongs to the ALAD family K01698 - 4.2.1.24 9.735e-199 632.0
WH2_k127_929554_2 helicase K17675 - 3.6.4.13 6.481e-198 620.0
WH2_k127_929554_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000001157 89.0
WH2_k127_9338318_0 The M ring may be actively involved in energy transduction K02409 - - 8.648e-267 830.0
WH2_k127_9338318_1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 540.0
WH2_k127_9338318_2 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000000000000000000000000000000000000000455 179.0
WH2_k127_9347830_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 601.0
WH2_k127_9347830_1 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 475.0
WH2_k127_9347830_2 Hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 358.0
WH2_k127_9347830_3 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 353.0
WH2_k127_9347830_4 - - - - 0.000000000000000000000000000000000000000000001114 169.0
WH2_k127_9347830_5 - - - - 0.0000000000000000000000000000000000000002708 153.0
WH2_k127_9347830_6 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000005078 79.0
WH2_k127_9350570_0 Polysaccharide biosynthesis protein - - - 5.112e-273 848.0
WH2_k127_9350570_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000001508 241.0
WH2_k127_9366759_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 0.0 1414.0
WH2_k127_9366759_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 401.0
WH2_k127_9366759_2 Protein of unknown function (DUF805) - - - 0.000000000000000000000000000000000000000000001052 169.0
WH2_k127_9500620_0 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 0.0 1289.0
WH2_k127_9500620_1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 4.182e-278 857.0
WH2_k127_9500620_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 5.369e-251 778.0
WH2_k127_9500620_3 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 546.0
WH2_k127_9500620_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 315.0
WH2_k127_9500620_5 MazG family K04765 - 3.6.1.9 0.00000000000000006375 80.0
WH2_k127_9517789_0 AMP-binding enzyme C-terminal domain - - - 2.632e-303 933.0
WH2_k127_9517789_1 UDP-N-acetylmuramate-alanine ligase K01924 - 6.3.2.8 6.787e-250 777.0
WH2_k127_9517789_2 proteins, homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 513.0
WH2_k127_9517789_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 499.0
WH2_k127_9517789_4 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000006855 130.0
WH2_k127_9565570_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 6.939e-243 756.0
WH2_k127_9565570_1 COG1253 Hemolysins and related proteins containing CBS domains K03699 - - 7.086e-217 680.0
WH2_k127_9565570_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 291.0
WH2_k127_9565570_3 Protein of unknown function (DUF3035) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004898 234.0
WH2_k127_9565570_4 Belongs to the ompA family - - - 0.00000000001984 66.0
WH2_k127_9586345_0 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009256 602.0
WH2_k127_9586345_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 489.0
WH2_k127_9590255_0 de-polymerase K05973 - 3.1.1.75 1.032e-251 778.0
WH2_k127_9590255_1 ABC-type multidrug transport system, ATPase and permease K06147 - - 1.342e-197 622.0
WH2_k127_9590255_2 Sel1 repeat protein K07126 - - 0.0000000000000007341 85.0
WH2_k127_963052_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 481.0
WH2_k127_963052_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 380.0
WH2_k127_963052_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 347.0
WH2_k127_963052_3 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 296.0
WH2_k127_963052_4 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000001958 181.0
WH2_k127_9689576_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.77e-271 839.0
WH2_k127_9689576_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000004437 148.0
WH2_k127_9717388_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 5.717e-229 712.0
WH2_k127_9717388_1 2-nitropropane dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 545.0
WH2_k127_9717388_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 422.0
WH2_k127_9717388_3 Peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001187 274.0
WH2_k127_9717388_4 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000002363 103.0
WH2_k127_9717388_5 Chromate transporter K07240 - - 0.00000000000000007997 82.0
WH2_k127_9763181_0 Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate K06447 - 1.2.1.71 2.456e-283 873.0
WH2_k127_9763181_1 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 523.0
WH2_k127_9763181_2 RarD protein K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 483.0
WH2_k127_9763181_3 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 474.0
WH2_k127_9763181_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005871 264.0
WH2_k127_9777937_0 chemotaxis protein K03407 - 2.7.13.3 0.0 1326.0
WH2_k127_9777937_1 chemotaxis K03406 - - 8.556e-285 887.0
WH2_k127_9777937_10 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 419.0
WH2_k127_9777937_11 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 323.0
WH2_k127_9777937_12 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009351 239.0
WH2_k127_9777937_13 chemotaxis K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000001962 230.0
WH2_k127_9777937_2 Protein of unknown function (DUF1800) - - - 3.125e-274 855.0
WH2_k127_9777937_3 chemotaxis K03406 - - 6.878e-270 841.0
WH2_k127_9777937_4 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 9.467e-266 825.0
WH2_k127_9777937_5 Tat pathway signal protein - - - 5.105e-247 772.0
WH2_k127_9777937_6 MatE - - - 1.148e-215 679.0
WH2_k127_9777937_7 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 564.0
WH2_k127_9777937_8 Aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 516.0
WH2_k127_9777937_9 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 508.0
WH2_k127_980375_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 480.0
WH2_k127_980375_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 336.0
WH2_k127_980375_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004595 262.0
WH2_k127_9818619_0 Extracellular solute-binding protein - - - 1.302e-272 848.0
WH2_k127_9818619_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 356.0
WH2_k127_9818619_2 type IV secretion system K03199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009331 263.0
WH2_k127_9818619_3 Type IV secretory pathway K03198 - - 0.000000000000000000000000000000000000000000000000000002624 190.0
WH2_k127_9818619_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000006016 184.0
WH2_k127_9818619_5 Type IV secretory pathway, VirB2 K03197 - - 0.0000000000000000000000000000000000000000000472 167.0
WH2_k127_9862150_0 Dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 488.0
WH2_k127_9862150_1 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 464.0
WH2_k127_9862150_2 Dehydrogenase K17760 - 1.1.9.1 0.000000000000000000000000000000000000000000000000000000000771 204.0
WH2_k127_9885808_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0 1076.0
WH2_k127_9885808_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 398.0
WH2_k127_9885808_2 Regulatory protein RecX K03565 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 292.0
WH2_k127_9885808_3 NADH ubiquinone oxidoreductase 17.2 kD subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002158 275.0
WH2_k127_9885808_4 Bacterial protein of unknown function (DUF839) K07093 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001394 280.0
WH2_k127_9885808_5 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000000000000000000000000001653 231.0
WH2_k127_9885808_7 recombinase activity - - - 0.00000000602 57.0
WH2_k127_9905_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.485e-265 824.0
WH2_k127_9905_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 593.0
WH2_k127_9905_2 ArsR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 521.0
WH2_k127_9905_3 Glycosyl hydrolase family 36 N-terminal domain K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000007737 250.0
WH2_k127_9931652_0 receptor - - - 2.799e-207 647.0
WH2_k127_9931652_1 Belongs to the glycosyl hydrolase 68 family K00692,K01193 GO:0005575,GO:0005576 2.4.1.10,3.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 535.0
WH2_k127_9931652_2 Transcriptional regulator sugar kinase K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000003937 261.0
WH2_k127_993388_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1145.0
WH2_k127_993388_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 3.066e-252 786.0
WH2_k127_993388_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000006633 190.0
WH2_k127_993388_11 - - - - 0.0000000000000000000000000000000008 135.0
WH2_k127_993388_2 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 601.0
WH2_k127_993388_3 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 488.0
WH2_k127_993388_4 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 439.0
WH2_k127_993388_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 428.0
WH2_k127_993388_6 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 374.0
WH2_k127_993388_7 Belongs to the MsrB Met sulfoxide reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 281.0
WH2_k127_993388_8 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000002655 238.0
WH2_k127_993388_9 COG0346 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000000000000000000000000000011 235.0