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Overview

ID MAG04127
Name WH2_bin.5
Sample SMP0107
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus Rhodoferax
Species
Assembly information
Completeness (%) 67.51
Contamination (%) 1.09
GC content (%) 62.0
N50 (bp) 5,772
Genome size (bp) 2,259,675

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2478

Gene name Description KEGG GOs EC E-value Score Sequence
WH2_k127_10066307_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 3.125e-258 798.0
WH2_k127_10066307_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.153e-229 717.0
WH2_k127_10066307_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 363.0
WH2_k127_10066307_3 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000000000000000000000000009588 229.0
WH2_k127_10066307_4 PFAM RNA-binding S4 domain protein K04762 - - 0.0000000000000000000000000000000000000000000000000000000002874 206.0
WH2_k127_10089278_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.152e-251 788.0
WH2_k127_10089278_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 487.0
WH2_k127_10089278_10 Thioesterase superfamily protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001779 234.0
WH2_k127_10089278_11 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000000000000000000000000000000000000000009034 169.0
WH2_k127_10089278_2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 477.0
WH2_k127_10089278_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 429.0
WH2_k127_10089278_4 Shikimate dehydrogenase substrate binding K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 362.0
WH2_k127_10089278_5 PFAM fumarate lyase K01857 - 5.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 358.0
WH2_k127_10089278_6 helix_turn_helix isocitrate lyase regulation K02624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 334.0
WH2_k127_10089278_7 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 319.0
WH2_k127_10089278_8 Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 318.0
WH2_k127_10089278_9 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 304.0
WH2_k127_10089360_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1449.0
WH2_k127_10089360_1 Exonuclease K02342 - 2.7.7.7 0.0 1017.0
WH2_k127_10089360_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0 1000.0
WH2_k127_10089360_3 Putative nucleotidyltransferase substrate binding domain K07182 - - 7.265e-198 634.0
WH2_k127_10089360_4 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 481.0
WH2_k127_10089360_5 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000003171 209.0
WH2_k127_10089360_6 - - - - 0.0000000000000000000008686 96.0
WH2_k127_10090883_0 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 541.0
WH2_k127_10090883_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 338.0
WH2_k127_10090883_2 PFAM Type II secretion system protein E K02669,K12203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 284.0
WH2_k127_10090883_3 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000003138 213.0
WH2_k127_10093777_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0 1386.0
WH2_k127_10093777_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.443e-226 707.0
WH2_k127_10093777_2 Ornithine-acyl acyl carrier protein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 464.0
WH2_k127_10093777_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 447.0
WH2_k127_10093777_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 353.0
WH2_k127_10093777_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 332.0
WH2_k127_10093777_6 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000006541 273.0
WH2_k127_10093777_7 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.00000000000000000000000000000000000000000008633 161.0
WH2_k127_10093777_8 - - - - 0.0000000000000000000029 99.0
WH2_k127_1009603_0 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 388.0
WH2_k127_1009603_1 peptidase S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 364.0
WH2_k127_1009603_2 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003855 271.0
WH2_k127_1009603_3 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000002986 194.0
WH2_k127_1009603_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000002358 133.0
WH2_k127_1009603_5 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000000001307 123.0
WH2_k127_1009603_6 peptidase S49 K04773 - - 0.00000000000000000001592 96.0
WH2_k127_10101504_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 604.0
WH2_k127_10101504_1 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 364.0
WH2_k127_10101504_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000001223 188.0
WH2_k127_1011754_0 DNA topoisomerase, type IA, central domain protein K03169 - 5.99.1.2 0.0 1177.0
WH2_k127_1011754_1 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 316.0
WH2_k127_1011754_2 PFAM nuclear protein SET K07117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 283.0
WH2_k127_1011754_3 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.00000000000000000000000001795 109.0
WH2_k127_1011754_4 Sporulation domain protein - - - 0.00000000000000002198 87.0
WH2_k127_10119323_0 Participates in both transcription termination and antitermination K02600 - - 7.006e-282 871.0
WH2_k127_10119323_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 287.0
WH2_k127_10119323_2 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001566 272.0
WH2_k127_10119323_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000003054 214.0
WH2_k127_10125044_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.842e-250 775.0
WH2_k127_10125044_1 Belongs to the thiolase family K00632 - 2.3.1.16 1.721e-225 702.0
WH2_k127_10125044_2 PFAM Extracellular ligand-binding receptor K01999 - - 3.7e-205 642.0
WH2_k127_10125044_3 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 431.0
WH2_k127_10125044_4 enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 382.0
WH2_k127_10125044_5 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 312.0
WH2_k127_10125044_6 phenylacetic acid degradation protein K02614 - - 0.0000000000000000000000000000000000000000000000000000000000000001303 227.0
WH2_k127_10134578_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 1.154e-219 695.0
WH2_k127_10134578_1 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 297.0
WH2_k127_10145069_0 Thiamine pyrophosphate enzyme, central domain K04103 - 4.1.1.74 8.131e-292 902.0
WH2_k127_10145069_1 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 569.0
WH2_k127_10153955_0 Male sterility protein - - - 0.0 1140.0
WH2_k127_10153955_1 PFAM poly granule associated family protein - - - 0.0000000000000000000000000000000000000193 151.0
WH2_k127_10170250_0 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 619.0
WH2_k127_10170250_1 acetyl-CoA hydrolase K18288 - - 0.00000000000000000000000000000000000000000000000000000000005919 211.0
WH2_k127_10173744_0 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.0 1060.0
WH2_k127_10173744_1 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 9.097e-239 749.0
WH2_k127_10173744_2 binding-protein-dependent transport systems inner membrane component K13894 - - 2.852e-211 658.0
WH2_k127_10173744_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 466.0
WH2_k127_10173744_4 Belongs to the ABC transporter superfamily K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 363.0
WH2_k127_10181001_0 PFAM Extracellular ligand-binding receptor K01999 - - 3.062e-214 669.0
WH2_k127_10181001_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 484.0
WH2_k127_10181001_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007543 265.0
WH2_k127_10181001_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000002716 213.0
WH2_k127_10185166_0 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 394.0
WH2_k127_10185166_1 Peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 364.0
WH2_k127_10185166_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000002033 206.0
WH2_k127_10185166_3 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000189 150.0
WH2_k127_10185166_4 - - - - 0.0000000000000000000000000000000000792 139.0
WH2_k127_10185166_5 - - - - 0.00000000000000000000000000000002054 133.0
WH2_k127_10185166_6 CsbD-like - - - 0.000000000000000000000582 102.0
WH2_k127_10185166_7 - - - - 0.0000000000002416 74.0
WH2_k127_10185166_8 TspO/MBR family K05770 - - 0.000004933 49.0
WH2_k127_10185272_0 Carboxylesterase family K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 437.0
WH2_k127_10185272_1 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 375.0
WH2_k127_10185272_2 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 353.0
WH2_k127_10185272_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005785 249.0
WH2_k127_10185272_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000002731 102.0
WH2_k127_10237139_0 Belongs to the thiolase family K00626 - 2.3.1.9 7.811e-235 729.0
WH2_k127_10237139_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 3.568e-231 724.0
WH2_k127_10237139_2 sigma54 specific, transcriptional regulator, Fis family K06714 - - 1.683e-208 656.0
WH2_k127_10237139_3 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 356.0
WH2_k127_10237139_4 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 319.0
WH2_k127_10237139_5 PFAM Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 284.0
WH2_k127_10237139_6 - - - - 0.0000000000001028 74.0
WH2_k127_10237139_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000006902 57.0
WH2_k127_10237139_8 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0001147 45.0
WH2_k127_1026078_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1110.0
WH2_k127_1026078_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 7.841e-233 724.0
WH2_k127_1026078_10 Staphylococcal nuclease homologue - - - 0.00000002256 58.0
WH2_k127_1026078_2 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 559.0
WH2_k127_1026078_3 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 432.0
WH2_k127_1026078_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 421.0
WH2_k127_1026078_5 Endonuclease exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 391.0
WH2_k127_1026078_6 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 321.0
WH2_k127_1026078_7 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000002058 250.0
WH2_k127_1026078_8 PFAM BLUF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001994 233.0
WH2_k127_1026078_9 Regulatory protein, FmdB family - - - 0.0000000000000000000000000000002062 126.0
WH2_k127_10301689_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.24e-259 803.0
WH2_k127_10301689_1 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000000000000002211 212.0
WH2_k127_10301689_2 Belongs to the bacterial ribosomal protein bL31 family K02909 - - 0.000000002985 57.0
WH2_k127_10341068_0 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 528.0
WH2_k127_10341068_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 426.0
WH2_k127_10341068_2 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 265.0
WH2_k127_10341068_3 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000000000000000000000000000000000000000000000000000000000004548 219.0
WH2_k127_10348640_0 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 474.0
WH2_k127_10348640_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 365.0
WH2_k127_10348640_2 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000004747 214.0
WH2_k127_10348640_3 PFAM ABC transporter related K01996 - - 0.00000000000000305 75.0
WH2_k127_10379455_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 9.922e-271 839.0
WH2_k127_10379455_1 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 1.023e-264 820.0
WH2_k127_10379455_2 diguanylate cyclase - - - 4.807e-260 821.0
WH2_k127_10379455_3 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 539.0
WH2_k127_10379455_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 370.0
WH2_k127_10379455_5 Lysine exporter protein (Lyse ygga) K11250 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 308.0
WH2_k127_10379455_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000008611 109.0
WH2_k127_10411028_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0 1051.0
WH2_k127_10411028_1 prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000002908 141.0
WH2_k127_10411028_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000006636 55.0
WH2_k127_10423448_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 605.0
WH2_k127_10423448_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 518.0
WH2_k127_10423448_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 482.0
WH2_k127_10423448_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000004063 248.0
WH2_k127_10423448_4 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000000000001926 204.0
WH2_k127_10430820_0 Glycosyl hydrolase family 1 K01223,K05350 - 3.2.1.21,3.2.1.86 1.457e-215 680.0
WH2_k127_10430820_1 PFAM phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 508.0
WH2_k127_10430820_2 Glycosyl hydrolases family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 467.0
WH2_k127_10430820_3 Glycosyl hydrolases family 17 K01210 - 3.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 444.0
WH2_k127_10430820_4 Periplasmic binding protein-like domain K02529,K05499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 438.0
WH2_k127_10430820_5 Glycosyl hydrolases family 17 - - - 0.0000000000000000000000000000000000000000000000000000000000000001253 224.0
WH2_k127_10430820_6 General secretion pathway protein F K02455 - - 0.00000000003867 63.0
WH2_k127_10435617_0 PFAM oxidoreductase domain protein K19181 - 1.1.1.292 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 579.0
WH2_k127_10435617_1 Shikimate dehydrogenase substrate binding domain protein K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 299.0
WH2_k127_10435617_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001291 274.0
WH2_k127_10435617_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K21395 - - 0.000000000000000000000006086 103.0
WH2_k127_10458579_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 353.0
WH2_k127_10458579_1 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.000000000000000000000000000000000001641 139.0
WH2_k127_10458579_2 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000000007905 99.0
WH2_k127_10458661_0 Histidine kinase K11527 - 2.7.13.3 1.913e-220 705.0
WH2_k127_10458661_1 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006661 266.0
WH2_k127_10458661_2 AzlC protein - - - 0.0000000000000000000000000000000000000000000001482 173.0
WH2_k127_10479429_0 peptide transport - - - 1.749e-202 653.0
WH2_k127_10479429_1 Protein of unknown function (DUF3348) - - - 0.000000000000000000000000000000000000000003053 164.0
WH2_k127_10479429_2 PFAM OmpA MotB domain protein - - - 0.000000000000000000000000000000001871 130.0
WH2_k127_10479429_3 Resolvase - - - 0.00004165 46.0
WH2_k127_10491369_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 568.0
WH2_k127_10491369_1 CHASE2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 520.0
WH2_k127_10491369_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 373.0
WH2_k127_10491369_3 STAS domain K06378 - - 0.000000000000000000001242 98.0
WH2_k127_10491369_4 OmpA family - - - 0.00000000006931 63.0
WH2_k127_10493694_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 552.0
WH2_k127_10493694_1 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 449.0
WH2_k127_10493694_2 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000007269 70.0
WH2_k127_10493694_3 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000003433 69.0
WH2_k127_10525601_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1278.0
WH2_k127_10544522_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1290.0
WH2_k127_10544522_1 Phosphate acetyl butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 6.397e-215 673.0
WH2_k127_10544522_2 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 320.0
WH2_k127_10544522_3 - - - - 0.0000000000000000000002543 101.0
WH2_k127_10568936_0 FtsX-like permease family K02004 - - 0.0 1230.0
WH2_k127_10568936_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 419.0
WH2_k127_10568936_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002683 250.0
WH2_k127_10568936_3 PFAM globin K06886 - - 0.0000000000000000000000000000000000000000000000000000000000000001684 223.0
WH2_k127_10568936_4 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000000000000000000000000003863 124.0
WH2_k127_10568936_5 Protein of unknown function (DUF1059) - - - 0.000000000000000000000000000003988 121.0
WH2_k127_10568936_6 Antitoxin component of a toxin-antitoxin (TA) module K18923 - - 0.000000000000000003612 88.0
WH2_k127_10568936_7 Type III restriction enzyme, res subunit - - - 0.000000000121 64.0
WH2_k127_10568936_8 - - - - 0.000009353 48.0
WH2_k127_10595426_0 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.000000000000000000000000000000000000000000000000000000000000000006063 228.0
WH2_k127_10595426_1 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000005772 224.0
WH2_k127_10595426_2 NYN domain - - - 0.000000000000000000000000000000000000000000000000001541 188.0
WH2_k127_10595426_3 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000000000365 136.0
WH2_k127_10595426_4 ThiS family - - - 0.0000000000000000000000000000061 121.0
WH2_k127_10595426_5 Protein of unknown function DUF86 - - - 0.000000001039 63.0
WH2_k127_10595426_6 zeta toxin - - - 0.0001356 48.0
WH2_k127_10634252_0 Putative diguanylate phosphodiesterase - - - 5.93e-279 892.0
WH2_k127_10634252_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 458.0
WH2_k127_10634252_2 Membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001795 243.0
WH2_k127_10634252_3 Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000001399 92.0
WH2_k127_10642966_0 PFAM ATP-binding region, ATPase domain protein K11711 - 2.7.13.3 9.365e-290 902.0
WH2_k127_10680112_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 5.915e-236 734.0
WH2_k127_10680112_1 glutamate--cysteine ligase K01919 - 6.3.2.2 3.093e-234 729.0
WH2_k127_10680112_2 Transport of potassium into the cell K03549 - - 0.00000000000000000004628 90.0
WH2_k127_10683711_0 Histidine kinase-like ATPases - - - 0.0 1527.0
WH2_k127_10683711_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1237.0
WH2_k127_10683711_2 amino acid K01999 - - 2.789e-215 677.0
WH2_k127_10683711_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 588.0
WH2_k127_10683711_4 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 460.0
WH2_k127_10683711_5 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 403.0
WH2_k127_10683711_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000000000002633 164.0
WH2_k127_10683711_7 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000001525 54.0
WH2_k127_10690693_0 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.0 1026.0
WH2_k127_10690693_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 1.215e-221 689.0
WH2_k127_10690693_2 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 551.0
WH2_k127_10690693_3 PIN domain K07065 - - 0.0000000000000006704 83.0
WH2_k127_10692660_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 552.0
WH2_k127_10692660_1 PFAM MucB RseB family protein K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 384.0
WH2_k127_10692660_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 318.0
WH2_k127_10692660_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000002279 257.0
WH2_k127_10692660_4 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.00000000000000000000000000000000000003381 153.0
WH2_k127_10692660_5 - - - - 0.0000000000000000000008291 102.0
WH2_k127_10722207_0 Belongs to the UbiD family K03182 - 4.1.1.98 7.485e-313 959.0
WH2_k127_10722207_1 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 360.0
WH2_k127_10722207_2 DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 340.0
WH2_k127_10722207_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 289.0
WH2_k127_10722207_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 284.0
WH2_k127_10722207_5 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000003474 218.0
WH2_k127_10722207_6 - - - - 0.000000000000000000000000000000000000004061 149.0
WH2_k127_10722207_7 ABC1 family - - - 0.0000000000000000000000001303 107.0
WH2_k127_10741411_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 447.0
WH2_k127_10741411_1 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 398.0
WH2_k127_10741411_2 PFAM cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 340.0
WH2_k127_10741411_3 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 291.0
WH2_k127_10748016_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 2292.0
WH2_k127_10748016_1 Peptidase U32 K08303 - - 1.366e-224 704.0
WH2_k127_10748016_2 glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 568.0
WH2_k127_10748016_3 PFAM monooxygenase FAD-binding K00480 - 1.14.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 508.0
WH2_k127_10748016_4 Sulfate permease family - - - 0.00000000000000000000000000000000000000000000000000000000000004164 241.0
WH2_k127_10778430_0 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 601.0
WH2_k127_10778430_1 permease K07089 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 540.0
WH2_k127_10778430_2 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 297.0
WH2_k127_10778430_3 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000002824 226.0
WH2_k127_10778430_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000333 215.0
WH2_k127_10778430_5 Thioredoxin domain - - - 0.00000000000000000000000000009637 125.0
WH2_k127_10780649_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K11711 - 2.7.13.3 2.654e-280 877.0
WH2_k127_10780649_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 1.865e-216 674.0
WH2_k127_10780649_10 - - - - 0.0000000000000000000000000000000000000000001952 164.0
WH2_k127_10780649_11 PFAM Thioredoxin K00384 - 1.8.1.9 0.0000000000000000000000000000000000005436 144.0
WH2_k127_10780649_2 Bacterial extracellular solute-binding protein, family 7 K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 490.0
WH2_k127_10780649_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 445.0
WH2_k127_10780649_4 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 430.0
WH2_k127_10780649_5 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 409.0
WH2_k127_10780649_6 Bacterial extracellular solute-binding protein, family 7 K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 364.0
WH2_k127_10780649_7 response regulator, receiver K11712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 339.0
WH2_k127_10780649_8 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000004337 244.0
WH2_k127_10780649_9 PFAM Restriction endonuclease K07448 - - 0.000000000000000000000000000000000000000000000000000000002293 208.0
WH2_k127_10802470_0 PFAM type III effector Hrp-dependent outers K21948 - 2.7.1.217 2.154e-214 672.0
WH2_k127_10802470_1 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 458.0
WH2_k127_10802470_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 442.0
WH2_k127_10802470_3 Class II aldolase adducin family protein K01628,K22130 - 4.1.1.104,4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 379.0
WH2_k127_10802470_4 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K08319 - 1.1.1.31,1.1.1.411 0.000000000000000000000000000000000000000000000000000000000000000001315 227.0
WH2_k127_10802470_5 Aldehyde dehydrogenase 1 family member A2 K07249 - 1.2.1.36 0.0000000000003868 70.0
WH2_k127_10826185_0 Diguanylate cyclase - - - 0.0 1389.0
WH2_k127_10826185_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 5.915e-245 762.0
WH2_k127_10826185_2 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 511.0
WH2_k127_10826185_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 377.0
WH2_k127_10826185_4 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007437 239.0
WH2_k127_10826185_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000001886 202.0
WH2_k127_10826185_6 PIN domain - - - 0.000000000000000000000000000000000000000000000000007195 183.0
WH2_k127_10826185_7 Belongs to the methyltransferase superfamily K07444 - - 0.000000000000000000000000000000000006654 136.0
WH2_k127_10826315_0 AAA domain K07028 - - 3.017e-214 677.0
WH2_k127_10826315_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 509.0
WH2_k127_10826315_2 Ligated ion channel L-glutamate- and glycine-binding site K02030,K10013,K10014,K10022 - - 0.000000000000000000000000000000000000000000000000008602 181.0
WH2_k127_10829868_0 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 604.0
WH2_k127_10829868_1 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 475.0
WH2_k127_10829868_2 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 336.0
WH2_k127_10829868_3 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 315.0
WH2_k127_10829868_4 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 305.0
WH2_k127_10829868_5 Pilus assembly protein TadZ N-terminal K02282 - - 0.00000000000000000000000000000002203 130.0
WH2_k127_10829868_6 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000009909 117.0
WH2_k127_10829868_7 LytR cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000001728 125.0
WH2_k127_10829868_8 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000004847 57.0
WH2_k127_10833804_0 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 9.198e-252 779.0
WH2_k127_10833804_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 4.722e-202 633.0
WH2_k127_10833804_2 protein conserved in bacteria K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 373.0
WH2_k127_1100157_0 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 3.553e-211 660.0
WH2_k127_1100157_1 ammonium transporter K03320 - - 0.00000000000000000000000000001951 117.0
WH2_k127_1100157_2 Helix-turn-helix domain - - - 0.0004623 46.0
WH2_k127_1110615_0 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 398.0
WH2_k127_1110615_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008551 394.0
WH2_k127_1120647_0 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 497.0
WH2_k127_1120647_1 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 350.0
WH2_k127_1120647_2 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 328.0
WH2_k127_1120647_3 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000005694 173.0
WH2_k127_1120647_4 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000003523 168.0
WH2_k127_1140934_0 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons - - - 7.533e-299 921.0
WH2_k127_1140934_1 Acyl-CoA dehydrogenase, type 2, C-terminal domain K00249,K07545 - 1.3.8.3,1.3.8.7 9.221e-216 674.0
WH2_k127_1140934_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 387.0
WH2_k127_1140934_3 Transcriptional regulator K16135 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 297.0
WH2_k127_1140934_4 helix_turn_helix isocitrate lyase regulation K02624 - - 0.000000000000000000000000000000000000000000000000001231 184.0
WH2_k127_1168794_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1180.0
WH2_k127_1168794_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 7.324e-258 801.0
WH2_k127_1168794_10 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000002579 194.0
WH2_k127_1168794_11 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000000000000007098 157.0
WH2_k127_1168794_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 1.164e-214 669.0
WH2_k127_1168794_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 605.0
WH2_k127_1168794_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 488.0
WH2_k127_1168794_5 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 460.0
WH2_k127_1168794_6 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 433.0
WH2_k127_1168794_7 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 333.0
WH2_k127_1168794_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002336 273.0
WH2_k127_1168794_9 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001924 255.0
WH2_k127_1176237_0 PFAM transposase Tn3 family protein - - - 0.0 1538.0
WH2_k127_1176237_1 cytochrome C - - - 0.0006046 45.0
WH2_k127_1203453_0 histidine kinase A domain protein - - - 2.234e-202 639.0
WH2_k127_1203453_1 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 581.0
WH2_k127_1203453_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 509.0
WH2_k127_1203453_3 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001541 246.0
WH2_k127_1203453_4 amino acid K11959 - - 0.00000000000000000000000000000000000000000000000001373 180.0
WH2_k127_1205811_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.814e-277 855.0
WH2_k127_1205811_1 peptidase U62, modulator of DNA gyrase K03568 - - 2.57e-277 856.0
WH2_k127_1205811_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002735 281.0
WH2_k127_1205811_11 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008933 239.0
WH2_k127_1205811_12 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000000000004561 214.0
WH2_k127_1205811_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000003283 199.0
WH2_k127_1205811_14 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000000000000000000000000000000000000007044 181.0
WH2_k127_1205811_15 Membrane - - - 0.0000000000005821 76.0
WH2_k127_1205811_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 3.625e-261 809.0
WH2_k127_1205811_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 3.045e-242 753.0
WH2_k127_1205811_4 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.755e-221 692.0
WH2_k127_1205811_5 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 6.731e-216 675.0
WH2_k127_1205811_6 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 5.762e-207 646.0
WH2_k127_1205811_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 2.208e-202 636.0
WH2_k127_1205811_8 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 541.0
WH2_k127_1205811_9 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 474.0
WH2_k127_1226123_0 homoserine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 605.0
WH2_k127_1226123_1 Bacterial extracellular solute-binding protein K05777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 550.0
WH2_k127_1226123_2 Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 449.0
WH2_k127_1226123_3 Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 304.0
WH2_k127_1226123_4 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 295.0
WH2_k127_1226123_5 DsrE/DsrF-like family K06039 - - 0.0000000000000000000000000000000000000000000105 164.0
WH2_k127_1226123_6 FCD K11475 - - 0.000000000000000000003953 94.0
WH2_k127_1226123_7 Glycosyltransferase like family 2 - - - 0.0000000000000008993 81.0
WH2_k127_1226123_8 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000001104 50.0
WH2_k127_1232446_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 388.0
WH2_k127_1232446_1 regulatory protein GntR HTH K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 336.0
WH2_k127_1232446_2 protein conserved in bacteria K07793 - - 0.0000000000000000000000000000000000000000000000000001858 188.0
WH2_k127_1232446_3 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 0.00000000000000000000000000000000000001797 146.0
WH2_k127_1232446_4 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000000000000000000001096 141.0
WH2_k127_1238939_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 9.126e-195 614.0
WH2_k127_1238939_1 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 458.0
WH2_k127_128075_0 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 1.289e-244 758.0
WH2_k127_128075_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 3.085e-224 700.0
WH2_k127_128075_2 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008106 242.0
WH2_k127_128075_3 phospholipase Carboxylesterase K06999 - - 0.000000000000000000000000000008367 119.0
WH2_k127_128075_4 Ppx GppA phosphatase - - - 0.00000000000000000000000000008979 121.0
WH2_k127_1285684_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1341.0
WH2_k127_1285684_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 319.0
WH2_k127_1285684_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000005766 105.0
WH2_k127_1297796_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 563.0
WH2_k127_1297796_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 418.0
WH2_k127_1297796_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 357.0
WH2_k127_1297796_3 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000000000000000000000006454 163.0
WH2_k127_1326698_0 PFAM homocysteine S-methyltransferase K00548 - 2.1.1.13 1.133e-215 672.0
WH2_k127_1326698_1 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 495.0
WH2_k127_1326698_2 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 488.0
WH2_k127_1326698_3 rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000002842 159.0
WH2_k127_1326698_4 - - - - 0.0000000000000000000000000001804 115.0
WH2_k127_1326698_5 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.00000000000000000000009435 99.0
WH2_k127_1360251_0 FAD dependent oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 413.0
WH2_k127_1360251_1 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 314.0
WH2_k127_1360251_2 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.0000000000000000000000002397 106.0
WH2_k127_1417904_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 3.028e-237 741.0
WH2_k127_1417904_1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000003374 186.0
WH2_k127_1417904_2 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000000000000000000000000000118 184.0
WH2_k127_1417904_3 dehydrogenase - - - 0.000000628 56.0
WH2_k127_1418502_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1045.0
WH2_k127_1418502_1 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 428.0
WH2_k127_1418502_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 347.0
WH2_k127_1418502_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000001573 114.0
WH2_k127_142315_0 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 401.0
WH2_k127_142315_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 398.0
WH2_k127_142315_2 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.000000000000000000000000000000002354 131.0
WH2_k127_142315_3 TIGRFAM thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000002168 81.0
WH2_k127_142315_4 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000009271 69.0
WH2_k127_1440492_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 8.282e-314 971.0
WH2_k127_1440492_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 424.0
WH2_k127_1440492_2 BRO family, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 317.0
WH2_k127_1451708_0 PFAM Type II secretion system protein E K02670 - - 2.49e-224 697.0
WH2_k127_1451708_1 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 498.0
WH2_k127_1451708_2 SMART Transport-associated and nodulation region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 306.0
WH2_k127_1451708_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000007252 231.0
WH2_k127_1544135_0 Transcriptional regulator, LysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 488.0
WH2_k127_1544135_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 329.0
WH2_k127_1544135_2 Anion-transporting ATPase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 298.0
WH2_k127_1544135_3 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.0000000000000000000000000000000000000000000000001919 179.0
WH2_k127_1544135_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.0000000000000000000000000001519 116.0
WH2_k127_1564463_0 Belongs to the transketolase family K00615 - 2.2.1.1 1.229e-250 780.0
WH2_k127_1564463_1 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 434.0
WH2_k127_1564463_2 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K02479 - - 0.0000000000000000000000000000000000000000000000000000000000005994 217.0
WH2_k127_1564463_3 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000005097 190.0
WH2_k127_1564463_4 CHASE domain - - - 0.0000000000000000000000000000002453 143.0
WH2_k127_1564463_5 Spore Coat Protein U domain - - - 0.0000000001171 69.0
WH2_k127_1574980_0 FAD linked oxidase domain protein - - - 0.0 1424.0
WH2_k127_1574980_1 type I secretion outer membrane protein, TolC family K12543 - - 1.532e-255 805.0
WH2_k127_1574980_2 Glutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 566.0
WH2_k127_1574980_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001836 277.0
WH2_k127_1574980_4 - - - - 0.000000000000000000000000000000000000000000000000000000003073 216.0
WH2_k127_1574980_5 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000001806 198.0
WH2_k127_1587276_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.215e-217 679.0
WH2_k127_1587276_1 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 569.0
WH2_k127_1587276_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000002644 179.0
WH2_k127_1609761_0 phosphate acetyltransferase K13788 - 2.3.1.8 0.0 1128.0
WH2_k127_1609761_1 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 1e-323 1000.0
WH2_k127_1609761_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.395e-274 848.0
WH2_k127_1609761_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 516.0
WH2_k127_1609761_4 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 476.0
WH2_k127_1609761_5 Protein of unknown function (DUF2894) - - - 0.0000000000000000000000000000000000000000002201 166.0
WH2_k127_1609761_6 OmpA family - - - 0.000000001222 59.0
WH2_k127_1624231_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 507.0
WH2_k127_1624231_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 433.0
WH2_k127_1624231_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 407.0
WH2_k127_1624231_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000002542 210.0
WH2_k127_1624231_4 Entericidin EcnA/B family - - - 0.0000000002302 63.0
WH2_k127_1633655_0 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 355.0
WH2_k127_1633655_1 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000002465 146.0
WH2_k127_1633655_2 Protein conserved in bacteria K09803 - - 0.0000000000000000000000000000000000001337 152.0
WH2_k127_1633655_3 - - - - 0.00000000000000000000000000000000001111 144.0
WH2_k127_1633655_5 - - - - 0.0000000000000000002133 94.0
WH2_k127_1685356_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1042.0
WH2_k127_1685356_1 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000004402 116.0
WH2_k127_1693215_0 Protein of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 597.0
WH2_k127_1693215_1 PFAM MltA domain protein K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 459.0
WH2_k127_1693215_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 355.0
WH2_k127_1727057_0 PFAM extracellular solute-binding protein family 1 K17315 - - 1.803e-210 658.0
WH2_k127_1727057_1 PFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 510.0
WH2_k127_1727057_2 Mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000007748 174.0
WH2_k127_175363_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 4.117e-291 896.0
WH2_k127_175363_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 1.359e-203 639.0
WH2_k127_175363_10 - - - - 0.0000000000008714 73.0
WH2_k127_175363_2 PFAM AFG1-family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008731 597.0
WH2_k127_175363_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 514.0
WH2_k127_175363_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 450.0
WH2_k127_175363_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 443.0
WH2_k127_175363_6 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 410.0
WH2_k127_175363_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 324.0
WH2_k127_175363_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001351 267.0
WH2_k127_175363_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001523 271.0
WH2_k127_1762448_0 Urate oxidase N-terminal - - - 3.013e-197 619.0
WH2_k127_1762448_1 oxidoreductase FAD NAD(P)-binding domain protein K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 532.0
WH2_k127_1762448_2 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 430.0
WH2_k127_1762448_3 PFAM SEC-C motif domain protein K07039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 375.0
WH2_k127_1762448_4 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 319.0
WH2_k127_1762448_5 Cysteine-rich secretory protein family - - - 0.00000000000000000001398 104.0
WH2_k127_1762448_6 SnoaL-like domain - - - 0.00000000000000004403 81.0
WH2_k127_176650_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1996.0
WH2_k127_176650_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0 1221.0
WH2_k127_176650_2 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 7.074e-221 691.0
WH2_k127_176650_3 Bacterial transglutaminase-like N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 441.0
WH2_k127_176650_4 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001096 273.0
WH2_k127_176650_5 activator of osmoprotectant transporter ProP K03607 - - 0.0000000000000000000000000000000000000000000000000000000000000000003099 237.0
WH2_k127_176650_6 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000009834 184.0
WH2_k127_1809660_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1027.0
WH2_k127_1809660_1 PrpF protein K16514 - 5.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 577.0
WH2_k127_1809660_2 Transcriptional regulator K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 501.0
WH2_k127_1831201_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.954e-267 827.0
WH2_k127_1831201_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 4.886e-259 809.0
WH2_k127_1831201_10 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 302.0
WH2_k127_1831201_11 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000142 196.0
WH2_k127_1831201_2 ribonuclease, Rne Rng family K08301 - - 1.201e-254 789.0
WH2_k127_1831201_3 Involved in the TonB-independent uptake of proteins K03641 - - 8.33e-210 659.0
WH2_k127_1831201_4 Glycosyltransferase Family 4 K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 457.0
WH2_k127_1831201_5 Glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 445.0
WH2_k127_1831201_6 SMART Nucleotide binding protein, PINc K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 420.0
WH2_k127_1831201_7 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 332.0
WH2_k127_1831201_8 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 321.0
WH2_k127_1831201_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 302.0
WH2_k127_1858297_0 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 9.213e-214 679.0
WH2_k127_1858297_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 419.0
WH2_k127_1858297_2 Transcriptional regulator, AraC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 400.0
WH2_k127_1858297_3 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000186 282.0
WH2_k127_1918055_0 PFAM Tetratricopeptide repeat - - - 2.596e-241 783.0
WH2_k127_1918055_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 7.322e-220 687.0
WH2_k127_1918055_2 Glycosyl hydrolase family 30 beta sandwich domain K01201 - 3.2.1.45 2.191e-205 648.0
WH2_k127_1918055_3 Transporter K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 596.0
WH2_k127_1918055_4 chondroitin AC lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 455.0
WH2_k127_1944715_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009438 501.0
WH2_k127_1944715_1 ATPase associated with various cellular activities, AAA_5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 454.0
WH2_k127_1944715_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 449.0
WH2_k127_1944715_3 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 381.0
WH2_k127_1944715_4 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001753 273.0
WH2_k127_1944715_5 response regulator K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006451 269.0
WH2_k127_1944715_6 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005529 233.0
WH2_k127_1944715_7 Histidine kinase K02484,K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001969 232.0
WH2_k127_1965385_0 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 587.0
WH2_k127_1965385_1 Phosphomethylpyrimidine kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 429.0
WH2_k127_1965385_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 318.0
WH2_k127_1965385_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000000003112 173.0
WH2_k127_1965385_4 Lipopolysaccharide assembly protein A domain K08992 - - 0.000000000000000000000000000007299 121.0
WH2_k127_1999296_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 415.0
WH2_k127_1999296_1 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 363.0
WH2_k127_1999296_2 - K06950 - - 0.000000002 63.0
WH2_k127_1999296_3 PFAM ATP-binding region, ATPase domain protein K02668 - 2.7.13.3 0.00000001143 59.0
WH2_k127_2048160_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1183.0
WH2_k127_2048160_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 539.0
WH2_k127_2048160_2 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 441.0
WH2_k127_2048160_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000000000000000000012 195.0
WH2_k127_2048280_0 Polysaccharide deacetylase K01452 - 3.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 442.0
WH2_k127_2048280_1 TIGRFAM Xanthine dehydrogenase accessory protein XdhC K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 323.0
WH2_k127_2048280_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000139 194.0
WH2_k127_2048280_3 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000000000000000000187 191.0
WH2_k127_2048280_4 PAS domain containing protein - - - 0.00000000000000004671 82.0
WH2_k127_2113310_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.979e-303 939.0
WH2_k127_2113310_1 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 447.0
WH2_k127_2113310_2 TIGRFAM TRAP transporter, DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 359.0
WH2_k127_2113310_3 Xylose isomerase-like TIM barrel K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 291.0
WH2_k127_2113310_4 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000000000000000000000000000000000004017 169.0
WH2_k127_2113310_5 Aldehyde dehydrogenase family K04072,K13922 - 1.1.1.1,1.2.1.10,1.2.1.87 0.0000000000000000000000008058 106.0
WH2_k127_213435_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1123.0
WH2_k127_213435_1 Required for chromosome condensation and partitioning K03529 - - 4.96e-197 619.0
WH2_k127_213435_2 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 422.0
WH2_k127_213435_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000001682 103.0
WH2_k127_2155022_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.41e-238 741.0
WH2_k127_2155022_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 340.0
WH2_k127_2155022_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 342.0
WH2_k127_2177886_0 PFAM extracellular solute-binding protein family 1 K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 569.0
WH2_k127_2177886_1 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 400.0
WH2_k127_2177886_2 PFAM Xanthine uracil vitamin C permease K02824 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001072 256.0
WH2_k127_2177886_3 Belongs to the Fur family K03711 - - 0.0000000000000000000002274 97.0
WH2_k127_2245564_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 589.0
WH2_k127_2245564_1 response regulator K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 405.0
WH2_k127_2272399_0 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 415.0
WH2_k127_2272399_1 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 343.0
WH2_k127_2272399_2 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000001575 151.0
WH2_k127_2274771_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 2.77e-199 629.0
WH2_k127_2274771_1 Ferrous iron transport protein B K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 454.0
WH2_k127_2274771_3 Protein of unknown function (DUF465) K09794 - - 0.00000000000000000002463 92.0
WH2_k127_2274771_4 FeoA K04758 - - 0.0000004685 54.0
WH2_k127_2288672_0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 1.789e-245 761.0
WH2_k127_2288672_1 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 533.0
WH2_k127_2288672_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 389.0
WH2_k127_2325283_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1250.0
WH2_k127_2333558_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 599.0
WH2_k127_2333558_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 411.0
WH2_k127_2333558_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000002167 240.0
WH2_k127_2333558_3 WLM domain K07043 - - 0.0000000000000000000000000000000000000000000000000000000003296 203.0
WH2_k127_2333558_4 PFAM translation initiation factor SUI1 K03113 - - 0.00000000000000000000000000000000000000000000000003655 182.0
WH2_k127_2333558_5 Putative quorum-sensing-regulated virulence factor K09954 - - 0.00000000000000000000000000000000006158 135.0
WH2_k127_2333558_6 - - - - 0.00000000000000000000000000003046 117.0
WH2_k127_2345695_0 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 519.0
WH2_k127_2345695_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 342.0
WH2_k127_2345695_2 PFAM Rieske 2Fe-2S domain protein - - - 0.0000000000000000000000000000000000000000000000000001657 187.0
WH2_k127_2345695_3 peptidase S49 K04773 - - 0.00000000000000000000000000008884 120.0
WH2_k127_2346581_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 1.777e-297 915.0
WH2_k127_2346581_1 glutamate synthase, alpha subunit domain protein K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 3.643e-214 668.0
WH2_k127_2346581_2 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 479.0
WH2_k127_2346581_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 457.0
WH2_k127_2346581_4 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 340.0
WH2_k127_2346581_5 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000137 259.0
WH2_k127_2365941_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1345.0
WH2_k127_2365941_1 PFAM alanine racemase domain protein K19967 - 4.1.2.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 532.0
WH2_k127_2365941_2 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 489.0
WH2_k127_2365941_3 belongs to the aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 457.0
WH2_k127_2365941_4 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 428.0
WH2_k127_2365941_5 Protein of unknown function (DUF721) - - - 0.000000000000000000004092 100.0
WH2_k127_2379439_0 Protein of unknown function (DUF4080) - - - 1.529e-223 709.0
WH2_k127_2379439_1 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 580.0
WH2_k127_2379439_10 DNA helicase - - - 0.0000000000000000000000000000000000008512 139.0
WH2_k127_2379439_2 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 483.0
WH2_k127_2379439_3 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 489.0
WH2_k127_2379439_4 Ethanolamine ammonia-lyase light chain (EutC) K03736 - 4.3.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 342.0
WH2_k127_2379439_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783,K03815 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 287.0
WH2_k127_2379439_6 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001291 247.0
WH2_k127_2379439_7 Belongs to the UPF0225 family K09858 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003465 242.0
WH2_k127_2379439_8 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000007057 234.0
WH2_k127_2379439_9 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000005559 152.0
WH2_k127_2408617_0 HflC and HflK could encode or regulate a protease K04088 - - 1.718e-216 680.0
WH2_k127_2408617_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 610.0
WH2_k127_2408617_2 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 509.0
WH2_k127_2408617_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000000003985 153.0
WH2_k127_2408617_4 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000000001499 87.0
WH2_k127_2408617_5 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000009448 51.0
WH2_k127_2412294_0 Threonine synthase K01733 - 4.2.3.1 2.522e-274 848.0
WH2_k127_2412294_1 PFAM aminotransferase, class I and II K14260 - 2.6.1.2,2.6.1.66 6.179e-263 812.0
WH2_k127_2412294_2 homoserine dehydrogenase K00003 - 1.1.1.3 3.872e-243 757.0
WH2_k127_2412294_3 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 505.0
WH2_k127_2412294_4 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 485.0
WH2_k127_2412294_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 305.0
WH2_k127_2412294_6 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004294 280.0
WH2_k127_2412294_7 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000003663 163.0
WH2_k127_2436975_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 4.324e-233 722.0
WH2_k127_2436975_1 TIGRFAM glycine cleavage system T protein K00605 - 2.1.2.10 2.92e-209 654.0
WH2_k127_2436975_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000003781 106.0
WH2_k127_2438011_0 PFAM SNF2-related protein - - - 0.0 1120.0
WH2_k127_2438011_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 608.0
WH2_k127_2438011_2 - - - - 0.00000000000000000000000000000000000000000000001329 175.0
WH2_k127_2438011_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000002064 73.0
WH2_k127_2447122_0 Protein of unknown function (DUF1631) - - - 8.005e-196 628.0
WH2_k127_2447122_1 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 565.0
WH2_k127_2447122_2 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 473.0
WH2_k127_2447122_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 442.0
WH2_k127_2447122_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 290.0
WH2_k127_246332_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 1.07e-245 766.0
WH2_k127_246332_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 441.0
WH2_k127_246332_2 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 403.0
WH2_k127_246332_3 peptidase K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 355.0
WH2_k127_246332_4 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 353.0
WH2_k127_246332_5 E3 Ubiquitin ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 332.0
WH2_k127_246332_6 LemA Family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 299.0
WH2_k127_246332_7 Haem-degrading K11477 - - 0.00000000000000000000000000000000000000000000000000000000000000001847 226.0
WH2_k127_246332_8 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003396 226.0
WH2_k127_246332_9 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000003966 144.0
WH2_k127_2466301_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1334.0
WH2_k127_2466301_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000001385 181.0
WH2_k127_247600_0 His Kinase A (phosphoacceptor) domain - - - 3.965e-263 831.0
WH2_k127_2502345_0 Cytochrome c554 and c-prime - - - 4.56e-307 950.0
WH2_k127_2502345_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 290.0
WH2_k127_2502345_2 Pfam cytochrome c K08738 - - 0.0000000000000000000000000000000000000000008671 158.0
WH2_k127_2502345_3 PFAM cytoplasmic chaperone TorD family protein - - - 0.0000000000000000000000000000000204 137.0
WH2_k127_2513831_0 D-galactarate dehydratase / Altronate hydrolase, C terminus K16846 - 4.4.1.24 2.855e-199 623.0
WH2_k127_2513831_1 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 432.0
WH2_k127_2513831_2 ABC-type sugar transport systems, permease components K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 408.0
WH2_k127_2513831_3 ABC-type sugar transport system, permease component K02026,K10238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 407.0
WH2_k127_2513831_4 UTRA domain K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 286.0
WH2_k127_2513831_5 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000003376 198.0
WH2_k127_2513831_6 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000000009597 147.0
WH2_k127_2607151_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1115.0
WH2_k127_2607151_1 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 511.0
WH2_k127_2607151_2 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 406.0
WH2_k127_2607151_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 400.0
WH2_k127_2607151_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000354 229.0
WH2_k127_2607151_5 - - - - 0.00000000000000000000000001152 111.0
WH2_k127_2609241_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.995e-277 855.0
WH2_k127_2609241_1 Cys Met metabolism pyridoxal-phosphate-dependent K01760 - 4.4.1.8 3.107e-205 644.0
WH2_k127_2609241_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 586.0
WH2_k127_2609241_3 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 499.0
WH2_k127_2609241_4 PFAM Phosphoribosyltransferase K07101 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 331.0
WH2_k127_2609241_5 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001693 276.0
WH2_k127_2609241_6 PFAM ABC transporter related K02003 - - 0.0000000000000000000000001235 108.0
WH2_k127_2609241_7 - - - - 0.00000004946 55.0
WH2_k127_2621547_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 574.0
WH2_k127_2621547_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 524.0
WH2_k127_2621547_2 Cysteine-rich CWC - - - 0.0000000000000000000001039 99.0
WH2_k127_2621547_3 - - - - 0.0000000000000000008793 91.0
WH2_k127_2623913_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 365.0
WH2_k127_2623913_1 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 344.0
WH2_k127_2623913_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 327.0
WH2_k127_2623913_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000005543 193.0
WH2_k127_2664990_0 Alanine dehydrogenase/PNT, C-terminal domain K00259 - 1.4.1.1 1.328e-206 647.0
WH2_k127_2664990_1 PFAM ABC transporter related K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 565.0
WH2_k127_2664990_2 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 546.0
WH2_k127_2664990_3 Protein of unknown function (DUF454) K09790 - - 0.00000000000000000000000000000000000000000000000000007895 190.0
WH2_k127_272728_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1995.0
WH2_k127_272728_1 Belongs to the CarA family K01956 - 6.3.5.5 2.194e-216 677.0
WH2_k127_272728_2 LysE type translocator K11250 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 355.0
WH2_k127_272728_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000512 79.0
WH2_k127_2736676_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 556.0
WH2_k127_2736676_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 428.0
WH2_k127_2736676_2 Mota tolq exbb proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 319.0
WH2_k127_2736676_3 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001945 244.0
WH2_k127_2736676_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000000000000000000000000000000000001293 223.0
WH2_k127_2736676_5 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000000000000000000000000000002899 200.0
WH2_k127_2736676_6 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000004907 193.0
WH2_k127_2736676_7 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000006377 122.0
WH2_k127_2739832_0 fad dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 415.0
WH2_k127_2739832_1 PFAM Asp Glu hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 404.0
WH2_k127_2739832_2 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 335.0
WH2_k127_2739832_3 Anti-sigma-K factor rskA - - - 0.0000000000000000000000000000000000000000001425 164.0
WH2_k127_2739832_4 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000004632 116.0
WH2_k127_2744177_0 Psort location CytoplasmicMembrane, score - - - 1.175e-300 939.0
WH2_k127_2744177_1 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009653 268.0
WH2_k127_2744177_2 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000001125 177.0
WH2_k127_2744177_3 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.000000000000000000259 92.0
WH2_k127_2744177_4 Transcriptional regulator K16135 - - 0.000000000002916 71.0
WH2_k127_2744833_0 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 1.554e-221 696.0
WH2_k127_2744833_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 613.0
WH2_k127_2744833_2 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 378.0
WH2_k127_2744833_3 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 360.0
WH2_k127_2755889_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 5.776e-321 989.0
WH2_k127_2755889_1 ABC 3 transport family K02075,K09816,K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 491.0
WH2_k127_2755889_2 Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 444.0
WH2_k127_2755889_3 ABC transporter K02074,K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 417.0
WH2_k127_2755889_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 394.0
WH2_k127_2755889_5 belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 287.0
WH2_k127_2755889_6 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001402 271.0
WH2_k127_2755889_7 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.000000000000000000000000000000000000000000000000000000000001896 220.0
WH2_k127_2767379_0 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress K05916,K07006,K21832 - 1.14.12.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 551.0
WH2_k127_2767379_1 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 486.0
WH2_k127_2767379_2 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 462.0
WH2_k127_2767379_3 Class III cytochrome C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 398.0
WH2_k127_2767379_4 Transcriptional regulator K07734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 369.0
WH2_k127_2767379_5 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 338.0
WH2_k127_2767379_6 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 317.0
WH2_k127_2767379_7 Belongs to the MtfA family K09933 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 311.0
WH2_k127_2771589_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 449.0
WH2_k127_2771589_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 444.0
WH2_k127_2771589_2 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 316.0
WH2_k127_2771589_3 Thioesterase superfamily protein K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002558 259.0
WH2_k127_2771589_4 Chorismate lyase K03181 - 4.1.3.40 0.00000000000000000000000000000000000000000000000000000004452 205.0
WH2_k127_2771589_5 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.000000000000000000000000000006069 119.0
WH2_k127_2771589_7 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.0000001912 53.0
WH2_k127_2783979_0 Major facilitator superfamily - - - 1.481e-237 739.0
WH2_k127_2783979_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 597.0
WH2_k127_2783979_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 336.0
WH2_k127_2783979_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000001761 137.0
WH2_k127_280813_0 PFAM HipA domain protein K07154 - 2.7.11.1 1.833e-217 679.0
WH2_k127_280813_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 539.0
WH2_k127_280813_10 - - - - 0.000000000000000000004535 93.0
WH2_k127_280813_11 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000001989 85.0
WH2_k127_280813_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002137 261.0
WH2_k127_280813_3 PFAM GCN5-related N-acetyltransferase K03824 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004492 261.0
WH2_k127_280813_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005629 232.0
WH2_k127_280813_5 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000000000000000000000000000002564 182.0
WH2_k127_280813_6 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000001763 131.0
WH2_k127_280813_7 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000009766 117.0
WH2_k127_280813_8 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000009439 108.0
WH2_k127_280813_9 Belongs to the 'phage' integrase family K04763,K07039 - - 0.00000000000000000000002363 103.0
WH2_k127_283361_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 577.0
WH2_k127_283361_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 559.0
WH2_k127_283361_2 PFAM amidohydrolase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001634 261.0
WH2_k127_283361_3 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000003578 189.0
WH2_k127_2853462_0 PFAM MOFRL domain protein K11529 - 2.7.1.165 1.014e-201 635.0
WH2_k127_2853462_1 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 576.0
WH2_k127_2853462_10 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01708,K16846 - 4.2.1.42,4.4.1.24 0.0000000000000000000000000000000000000002924 149.0
WH2_k127_2853462_2 Periplasmic binding protein LacI transcriptional regulator K06145 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 552.0
WH2_k127_2853462_3 6-phosphogluconate dehydrogenase, NAD-binding K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 491.0
WH2_k127_2853462_4 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 465.0
WH2_k127_2853462_5 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 446.0
WH2_k127_2853462_6 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 289.0
WH2_k127_2853462_7 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K21393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003416 245.0
WH2_k127_2853462_8 - - - - 0.000000000000000000000000000000000000000000000000000000000001059 212.0
WH2_k127_2853462_9 Shikimate kinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000001782 169.0
WH2_k127_2876738_0 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 442.0
WH2_k127_2876738_1 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 415.0
WH2_k127_2876738_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 405.0
WH2_k127_2876738_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000007379 250.0
WH2_k127_2876738_4 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000001498 120.0
WH2_k127_2881665_0 Bacterial protein of unknown function (DUF839) K07093 - - 0.0 1242.0
WH2_k127_2881665_1 STAS domain K03321 - - 7.282e-238 755.0
WH2_k127_2881665_2 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 555.0
WH2_k127_2881665_3 Hemerythrin K07216 - - 0.0000001407 60.0
WH2_k127_2889028_0 Diguanylate cyclase - - - 3.555e-290 912.0
WH2_k127_2889028_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 502.0
WH2_k127_2889028_2 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 497.0
WH2_k127_2889028_3 - - - - 0.000000000000000000000000000000000000000006036 158.0
WH2_k127_2889028_4 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 GO:0003674,GO:0003824,GO:0006091,GO:0006457,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0022900,GO:0044237,GO:0050896,GO:0055114 - 0.0000000000000000000000000000000004061 138.0
WH2_k127_2896160_0 Belongs to the IlvD Edd family K13875 - 4.2.1.25 0.0 1069.0
WH2_k127_2896160_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K21393 - - 1.282e-241 751.0
WH2_k127_2896160_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 567.0
WH2_k127_2896160_3 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 435.0
WH2_k127_2896160_4 regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 392.0
WH2_k127_2896160_5 KDPG and KHG aldolase K01631 - 4.1.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 314.0
WH2_k127_2896160_6 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 305.0
WH2_k127_2896160_7 belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.00000000000000000000000000000000004506 134.0
WH2_k127_2913573_0 Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
WH2_k127_2913573_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 320.0
WH2_k127_2913573_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000008406 239.0
WH2_k127_2915604_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 398.0
WH2_k127_2915604_1 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 386.0
WH2_k127_2915604_2 Trap-type c4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000006013 203.0
WH2_k127_2927927_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 375.0
WH2_k127_2927927_1 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000000001813 166.0
WH2_k127_2927927_2 cytochrome - - - 0.0000000000000000000000001425 109.0
WH2_k127_2927927_3 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 0.00001976 48.0
WH2_k127_2946856_0 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 589.0
WH2_k127_2946856_1 sulfur relay protein TusD DsrE K07235 - - 0.00000000000000000000000000000000000000000000000000000000000002859 215.0
WH2_k127_2946856_2 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000000001857 203.0
WH2_k127_2946856_3 Sulfur relay protein TusC DsrF K07236 - - 0.0000000000000000000000000000000000000000000000000003336 187.0
WH2_k127_2946856_4 DsrH like protein K07237 - - 0.0000000000000000000000000009162 115.0
WH2_k127_2946856_5 Nitrate reductase gamma subunit - - - 0.00000000000000001153 88.0
WH2_k127_2949470_0 GAF domain - - - 1.537e-271 861.0
WH2_k127_2949470_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 372.0
WH2_k127_2949470_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 330.0
WH2_k127_2949470_3 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000046 271.0
WH2_k127_2949470_4 - - - - 0.00000000000000000000000000000000000000000000000004089 187.0
WH2_k127_2949470_5 Esterase PHB depolymerase - - - 0.000000000000000000000000000008706 130.0
WH2_k127_2949470_6 Protein of unknown function (DUF3309) - - - 0.0000000000000000000102 91.0
WH2_k127_2949470_7 KaiB domain K08481 - - 0.00000000000000001312 86.0
WH2_k127_2949470_8 Collagen triple helix repeat (20 copies) - - - 0.0000000000003928 74.0
WH2_k127_2980706_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0 1074.0
WH2_k127_2980706_1 Von Willebrand factor type A K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 327.0
WH2_k127_2980706_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000001352 203.0
WH2_k127_2980706_3 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000008141 187.0
WH2_k127_3066855_0 Histidine kinase K11527 - 2.7.13.3 3.133e-278 886.0
WH2_k127_3066855_1 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 601.0
WH2_k127_3066855_2 SMART GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000002255 198.0
WH2_k127_3108895_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1469.0
WH2_k127_3108895_1 aminotransferase class I and II - - - 3.512e-281 868.0
WH2_k127_3108895_10 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000001243 142.0
WH2_k127_3108895_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K00836,K07250 - 2.6.1.19,2.6.1.22,2.6.1.76 4.067e-234 731.0
WH2_k127_3108895_3 binding-protein-dependent transport systems inner membrane component K02054 - - 4.072e-205 644.0
WH2_k127_3108895_4 PFAM extracellular solute-binding protein family 1 K02055 - - 2.142e-203 635.0
WH2_k127_3108895_5 Belongs to the arginase family K12255 - 3.5.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 583.0
WH2_k127_3108895_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 574.0
WH2_k127_3108895_7 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 462.0
WH2_k127_3108895_8 binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 453.0
WH2_k127_3108895_9 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 373.0
WH2_k127_3131963_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1423.0
WH2_k127_3131963_1 4Fe-4S binding domain K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 450.0
WH2_k127_3131963_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 456.0
WH2_k127_3131963_3 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 370.0
WH2_k127_3131963_4 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 338.0
WH2_k127_3131963_5 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 301.0
WH2_k127_3131963_6 PFAM UspA domain protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001529 263.0
WH2_k127_3131963_7 - - - - 0.000000000000000000000000000003359 124.0
WH2_k127_3157180_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.793e-269 835.0
WH2_k127_3157180_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 6.242e-233 724.0
WH2_k127_3157180_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 344.0
WH2_k127_3157180_3 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 310.0
WH2_k127_3157180_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000001764 111.0
WH2_k127_3157180_5 - - - - 0.00000000004777 63.0
WH2_k127_3157180_6 - - - - 0.000000001429 59.0
WH2_k127_3170565_0 Trap dicarboxylate transporter, dctm subunit - - - 1.766e-212 665.0
WH2_k127_3170565_1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 290.0
WH2_k127_3170565_2 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000159 279.0
WH2_k127_3170565_3 Belongs to the DapA family K21062 - 3.5.4.22 0.000000000000000000000000000000000000000000000000000000000001337 209.0
WH2_k127_3171371_0 von Willebrand factor, type A K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 508.0
WH2_k127_3171371_1 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 418.0
WH2_k127_3171371_2 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001229 267.0
WH2_k127_3171371_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000003687 200.0
WH2_k127_3177150_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1018.0
WH2_k127_3177150_1 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 313.0
WH2_k127_3177150_2 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000003141 183.0
WH2_k127_323189_0 pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 550.0
WH2_k127_323189_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 407.0
WH2_k127_323189_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 302.0
WH2_k127_323189_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 297.0
WH2_k127_3260712_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.781e-256 803.0
WH2_k127_3260712_1 Major facilitator superfamily K08218 - - 6.03e-228 711.0
WH2_k127_3260712_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000002767 149.0
WH2_k127_3260712_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000003773 132.0
WH2_k127_3260712_12 redox protein regulator of disulfide bond formation - - - 0.000000000000000000293 92.0
WH2_k127_3260712_2 hmm pf06808 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 582.0
WH2_k127_3260712_3 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 492.0
WH2_k127_3260712_4 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 440.0
WH2_k127_3260712_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 409.0
WH2_k127_3260712_6 Two component transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 394.0
WH2_k127_3260712_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 361.0
WH2_k127_3260712_8 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000006247 193.0
WH2_k127_3260712_9 - - - - 0.00000000000000000000000000000000000000000000000000003978 197.0
WH2_k127_326444_0 Proton-conducting membrane transporter K12141 - - 1.333e-279 863.0
WH2_k127_326444_1 Proton-conducting membrane transporter - - - 4.689e-260 805.0
WH2_k127_326444_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 1.936e-244 764.0
WH2_k127_326444_3 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 523.0
WH2_k127_326444_4 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 365.0
WH2_k127_326444_5 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 316.0
WH2_k127_326444_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 298.0
WH2_k127_326444_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000001521 123.0
WH2_k127_3264580_0 Belongs to the LDH2 MDH2 oxidoreductase family K13609 - 1.5.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 445.0
WH2_k127_3264580_1 Proline racemase K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000004145 262.0
WH2_k127_3264580_2 Belongs to the proline racemase family K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000007877 250.0
WH2_k127_3270151_0 Binding-protein-dependent transport system inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 547.0
WH2_k127_3270151_1 binding-protein-dependent transport systems inner membrane component K17317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 291.0
WH2_k127_3270151_2 PFAM extracellular solute-binding protein family 1 K17315 - - 0.0000000000000000000000000000000000000000000000000000000001196 204.0
WH2_k127_32961_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K13796 - - 5.073e-288 885.0
WH2_k127_32961_1 PFAM fumarate lyase K01857 - 5.5.1.2 1.563e-279 859.0
WH2_k127_3320495_0 diguanylate cyclase - - - 9.076e-316 984.0
WH2_k127_3320495_1 Belongs to the ABC transporter superfamily K10112 - - 1.063e-204 639.0
WH2_k127_3320495_2 binding-protein-dependent transport systems inner membrane component K17317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 316.0
WH2_k127_3363554_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 418.0
WH2_k127_3363554_1 transcription regulator, contains HTH domain (MarR family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001468 251.0
WH2_k127_3363554_2 Tripartite ATP-independent periplasmic transporter subunit DctQ family protein 5 - - - 0.000000000000000000003466 96.0
WH2_k127_3363554_3 Ferrous iron transport protein B K04759 - - 0.00000000009533 63.0
WH2_k127_3382102_0 TRAP dicarboxylate transporter K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 555.0
WH2_k127_3382102_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001178 279.0
WH2_k127_3382102_2 Tripartite ATP-independent periplasmic transporter, DctQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002779 241.0
WH2_k127_3382102_3 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.0000000000000000000000000000000000000007076 148.0
WH2_k127_3408235_0 beta' subunit K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 606.0
WH2_k127_3408235_1 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 576.0
WH2_k127_3408235_2 PFAM Ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 513.0
WH2_k127_3408235_3 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006358 233.0
WH2_k127_3408235_4 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000897 155.0
WH2_k127_3409945_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.187e-251 782.0
WH2_k127_3409945_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 597.0
WH2_k127_3409945_2 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 516.0
WH2_k127_3409945_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 437.0
WH2_k127_3409945_4 PFAM HhH-GPD family protein K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 371.0
WH2_k127_3409945_5 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000000009412 142.0
WH2_k127_341297_0 PFAM peptidase U32 K08303 - - 8.217e-240 751.0
WH2_k127_341297_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 8.189e-211 657.0
WH2_k127_341297_2 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005358 231.0
WH2_k127_341297_3 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000000000000000000000000000006434 192.0
WH2_k127_341297_4 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 0.000000000000000000000000000000002031 131.0
WH2_k127_341297_5 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.0008835 45.0
WH2_k127_3445436_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 579.0
WH2_k127_3445436_1 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 477.0
WH2_k127_3445436_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 447.0
WH2_k127_3445436_3 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000003384 120.0
WH2_k127_3445436_4 Histidine kinase-like ATPase domain - - - 0.000009283 51.0
WH2_k127_3475708_0 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 1.115e-217 679.0
WH2_k127_3475708_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 9.414e-217 675.0
WH2_k127_3475708_2 PFAM binding-protein-dependent transport systems inner membrane component K11075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 546.0
WH2_k127_3475708_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 0.00000000001722 64.0
WH2_k127_3475708_4 PFAM binding-protein-dependent transport systems inner membrane component K11074 - - 0.00009202 45.0
WH2_k127_3502613_0 Histidine kinase - - - 5.959e-242 768.0
WH2_k127_3502613_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 284.0
WH2_k127_3502613_2 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001086 286.0
WH2_k127_3502613_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000001857 252.0
WH2_k127_3502613_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006058 252.0
WH2_k127_3502613_5 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000002647 214.0
WH2_k127_3502613_6 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000003749 168.0
WH2_k127_3502613_7 - - - - 0.00000000000001168 82.0
WH2_k127_3559015_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.752e-312 960.0
WH2_k127_3559015_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.204e-261 809.0
WH2_k127_3561294_0 fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 568.0
WH2_k127_3561294_1 Belongs to the DapA family K01714,K13876 - 4.2.1.43,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 557.0
WH2_k127_3561294_2 PFAM fumarylacetoacetate (FAA) hydrolase K16856 - 4.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 520.0
WH2_k127_3561294_3 Belongs to the IlvD Edd family K13875 - 4.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 411.0
WH2_k127_3561294_4 PFAM Short-chain dehydrogenase reductase SDR K18335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 376.0
WH2_k127_3561294_5 KR domain K00059 - 1.1.1.100 0.000000000001221 67.0
WH2_k127_3563233_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1144.0
WH2_k127_3563233_1 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 2.161e-288 904.0
WH2_k127_3563233_10 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 338.0
WH2_k127_3563233_11 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 305.0
WH2_k127_3563233_12 Lysine exporter protein (Lyse ygga) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 291.0
WH2_k127_3563233_13 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 288.0
WH2_k127_3563233_14 esterase of the alpha beta K07002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001747 259.0
WH2_k127_3563233_15 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000001813 203.0
WH2_k127_3563233_16 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000863 143.0
WH2_k127_3563233_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 5.755e-245 768.0
WH2_k127_3563233_3 PFAM binding-protein-dependent transport systems inner membrane component K02026,K17243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 569.0
WH2_k127_3563233_4 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 482.0
WH2_k127_3563233_5 ATPase component of ABC-type sugar transporter K10191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 475.0
WH2_k127_3563233_6 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 466.0
WH2_k127_3563233_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 371.0
WH2_k127_3563233_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 368.0
WH2_k127_3563233_9 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 340.0
WH2_k127_3565789_0 TIGRFAM type I secretion system ATPase K12541 - - 0.0 1200.0
WH2_k127_3565789_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000001242 157.0
WH2_k127_3569794_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 613.0
WH2_k127_3569794_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 431.0
WH2_k127_3569794_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000001656 56.0
WH2_k127_3587292_0 May be involved in recombinational repair of damaged DNA K03631 - - 4.643e-247 773.0
WH2_k127_3587292_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 591.0
WH2_k127_3587292_2 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 546.0
WH2_k127_3587292_3 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 480.0
WH2_k127_3587292_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 475.0
WH2_k127_3587292_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 364.0
WH2_k127_3587292_6 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 364.0
WH2_k127_3587292_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 319.0
WH2_k127_3587292_8 Outer membrane lipoprotein K02494 - - 0.0000000000000000000000000000000000003958 146.0
WH2_k127_3587292_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000001393 89.0
WH2_k127_3592177_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 297.0
WH2_k127_3592177_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 282.0
WH2_k127_3592177_2 PFAM Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 283.0
WH2_k127_3592177_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000739 126.0
WH2_k127_3659946_0 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 7.143e-257 796.0
WH2_k127_3659946_1 Fumarate lyase K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 385.0
WH2_k127_3686366_0 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 481.0
WH2_k127_3686366_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 462.0
WH2_k127_3686366_2 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 347.0
WH2_k127_3700156_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.0 1054.0
WH2_k127_3700156_1 PFAM glycoside hydrolase, family 13 domain protein K01214,K02438 - 3.2.1.196,3.2.1.68 4.629e-318 996.0
WH2_k127_3700156_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.373e-256 810.0
WH2_k127_3700156_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 3.76e-245 764.0
WH2_k127_3700156_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.319e-221 695.0
WH2_k127_3700156_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.336e-218 684.0
WH2_k127_3700156_6 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 303.0
WH2_k127_3700719_0 Protein of unknown function (DUF1298) - - - 2.494e-233 733.0
WH2_k127_3700719_1 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 564.0
WH2_k127_3700719_2 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 469.0
WH2_k127_3700719_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 368.0
WH2_k127_3700719_4 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 347.0
WH2_k127_3700719_5 Bacterial transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 325.0
WH2_k127_3700719_6 PFAM acyl-coA-binding protein, ACBP - - - 0.00000000000000000000000000000000000002318 144.0
WH2_k127_3700719_7 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000000000000000000000007609 136.0
WH2_k127_3700719_8 Domain of unknown function (DUF1840) - - - 0.0000000000000000000000000000008914 125.0
WH2_k127_3700719_9 PFAM poly granule associated family protein - - - 0.000000000000000000000000000003389 123.0
WH2_k127_3709250_0 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 289.0
WH2_k127_3709250_1 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 283.0
WH2_k127_3709250_2 ribonuclease, Rne Rng family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004112 269.0
WH2_k127_3709250_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001894 265.0
WH2_k127_3709250_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000001445 51.0
WH2_k127_37185_0 NMT1-like family K02051,K15576,K22067 - - 1.581e-260 806.0
WH2_k127_37185_1 Nitrate ABC transporter inner membrane subunit K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 510.0
WH2_k127_37185_2 ANTAR K07183 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 377.0
WH2_k127_37185_3 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 367.0
WH2_k127_37185_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 359.0
WH2_k127_37185_5 PFAM Cyclic nucleotide-binding K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 299.0
WH2_k127_37185_6 Ribonucleotide reductase subunit alpha - - - 0.00000000000000000000000000000000000000004393 157.0
WH2_k127_37185_7 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.0000000000000000000002955 95.0
WH2_k127_37185_8 Pfam Ankyrin K10799 - 2.4.2.30 0.00008977 49.0
WH2_k127_3736001_0 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 488.0
WH2_k127_3736001_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 434.0
WH2_k127_3736001_2 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 373.0
WH2_k127_3736001_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000007043 238.0
WH2_k127_3736001_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000001139 235.0
WH2_k127_3736001_5 Type II secretion system K02653 - - 0.0000000000000000000000001439 106.0
WH2_k127_3736001_6 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000000000007516 96.0
WH2_k127_3748279_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 556.0
WH2_k127_3748279_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 543.0
WH2_k127_3748279_10 PFAM Phosphoribosyl transferase domain K07100 - - 0.00001378 50.0
WH2_k127_3748279_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 495.0
WH2_k127_3748279_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 481.0
WH2_k127_3748279_4 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 464.0
WH2_k127_3748279_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 381.0
WH2_k127_3748279_6 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000001841 127.0
WH2_k127_3748279_7 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000002702 112.0
WH2_k127_3748279_8 - - - - 0.000000000000000003133 88.0
WH2_k127_3748279_9 - - - - 0.0000000000000003276 84.0
WH2_k127_3760828_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 407.0
WH2_k127_3760828_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 366.0
WH2_k127_3760828_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 338.0
WH2_k127_3760828_3 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 313.0
WH2_k127_3760828_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000000001887 195.0
WH2_k127_3760828_5 SlyX K03745 - - 0.0000000000000000005736 89.0
WH2_k127_3829356_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 3.239e-272 842.0
WH2_k127_3829356_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 546.0
WH2_k127_3829356_2 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 300.0
WH2_k127_3829356_3 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000000000000000000000006603 219.0
WH2_k127_3829356_4 TIGRFAM phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000001226 131.0
WH2_k127_3829356_5 PFAM cytochrome c - - - 0.00000000000000008817 81.0
WH2_k127_3849162_0 Cytochrome c bacterial - - - 7.154e-204 642.0
WH2_k127_3849162_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 424.0
WH2_k127_3874973_0 PFAM AsmA family protein K07289,K07290 - - 1.179e-243 770.0
WH2_k127_3874973_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 369.0
WH2_k127_3874973_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000516 220.0
WH2_k127_3874973_3 SMART Transport-associated and nodulation region K04065 - - 0.00000000000000000000000000000000000000006599 153.0
WH2_k127_3874973_4 YXWGXW repeat (2 copies) - - - 0.00000000000000000000000000000000001499 139.0
WH2_k127_3874973_5 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000002232 128.0
WH2_k127_3977819_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.473e-241 751.0
WH2_k127_3977819_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000002717 188.0
WH2_k127_3977819_2 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000000000000000002082 159.0
WH2_k127_3977819_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000002594 136.0
WH2_k127_3977819_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000000005712 86.0
WH2_k127_3983100_0 Major facilitator superfamily - - - 9.824e-198 622.0
WH2_k127_3983100_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 449.0
WH2_k127_3983100_2 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 343.0
WH2_k127_3983100_3 Cytochrome c bacterial - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 323.0
WH2_k127_3983100_5 PFAM DsrE DsrF-like family - - - 0.00000000000000000000000000000000006745 139.0
WH2_k127_3983100_6 - - - - 0.00000000000000000000000272 106.0
WH2_k127_3983100_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000009623 99.0
WH2_k127_3983100_8 toxin-antitoxin pair type II binding - - - 0.000000004753 60.0
WH2_k127_3983100_9 type II restriction enzyme, methylase - - - 0.0006531 44.0
WH2_k127_3986750_0 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 571.0
WH2_k127_3986750_1 Protocatechuate 4,5-dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 524.0
WH2_k127_3986750_2 PFAM Extradiol ring-cleavage dioxygenase LigAB LigA subunit K04100 - 1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000152 255.0
WH2_k127_3986750_3 PFAM Amidohydrolase 2 K10221 - 3.1.1.57 0.0000000000000000000000000000000000000000000000000000000000006139 210.0
WH2_k127_4002958_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.224e-230 724.0
WH2_k127_4002958_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 589.0
WH2_k127_4002958_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000000000000000000000003315 216.0
WH2_k127_4002958_3 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000005738 207.0
WH2_k127_4002958_4 - - - - 0.0000000000000000000000000000000000000000000000000001371 187.0
WH2_k127_4002958_5 Mut7-C ubiquitin - - - 0.000000000000000000000000000000000002044 140.0
WH2_k127_4002958_6 Phosphomethylpyrimidine kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000836 130.0
WH2_k127_4002958_7 Helix-hairpin-helix motif K02237 - - 0.000000000000000000000000001725 114.0
WH2_k127_411723_0 Belongs to the IlvD Edd family K13875 - 4.2.1.25 7.302e-276 850.0
WH2_k127_411723_1 PAC sensor containing diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 597.0
WH2_k127_411723_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 436.0
WH2_k127_411723_3 Class II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000004017 224.0
WH2_k127_411723_4 - - - - 0.0000000000000000000000000000000005881 138.0
WH2_k127_4183431_0 formate hydrogenlyase subunit 3 multisubunit Na H antiporter, MnhD subunit K05568,K12137 - - 1.508e-246 773.0
WH2_k127_4183431_1 SMART transcription factor jumonji jmjC K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 568.0
WH2_k127_4183431_2 Proton-conducting membrane transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000002045 237.0
WH2_k127_4183431_3 Peptidylprolyl isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000005891 166.0
WH2_k127_4183431_4 - - - - 0.0000000000000000000000000009376 116.0
WH2_k127_420238_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K11711 - 2.7.13.3 1.747e-279 875.0
WH2_k127_420238_1 response regulator, receiver K11712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 346.0
WH2_k127_420238_2 - - - - 0.00000000000000000000000000000000000000000001148 168.0
WH2_k127_420238_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000003344 162.0
WH2_k127_420238_4 alcohol dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.0001291 46.0
WH2_k127_4250116_0 Domain of Unknown Function (DUF349) - - - 0.0 1207.0
WH2_k127_4250116_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 297.0
WH2_k127_4250116_2 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 299.0
WH2_k127_4292922_0 PFAM FAD dependent oxidoreductase K07137 - - 0.0 1015.0
WH2_k127_4292922_1 PFAM aminotransferase class V - - - 1.883e-211 660.0
WH2_k127_4292922_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 499.0
WH2_k127_4292922_3 Transcriptional regulator K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000004891 229.0
WH2_k127_429504_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 468.0
WH2_k127_429504_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 401.0
WH2_k127_429504_2 PFAM Thioredoxin domain K03671 - - 0.000000000000000000000000000000000000000000000000000000001732 203.0
WH2_k127_429504_3 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000000000000001409 182.0
WH2_k127_429504_4 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000006446 160.0
WH2_k127_429504_5 - - - - 0.00000000000000000000000000000000000000003394 156.0
WH2_k127_429504_6 - - - - 0.00000000000000000000000000000000007761 142.0
WH2_k127_4296866_0 Amidase K02433,K19837 - 3.5.1.84,6.3.5.6,6.3.5.7 6.065e-234 731.0
WH2_k127_4296866_1 PFAM Basic membrane lipoprotein K02058,K07335 - - 2.23e-204 643.0
WH2_k127_4296866_2 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 521.0
WH2_k127_4296866_3 Protein of unknown function (DUF3225) - - - 0.000000000000000000000000000000000000000000000000000000000001471 212.0
WH2_k127_4296866_4 binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000001165 124.0
WH2_k127_432964_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 1.452e-277 855.0
WH2_k127_432964_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 525.0
WH2_k127_432964_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 477.0
WH2_k127_432964_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 336.0
WH2_k127_4349289_0 Bacterial periplasmic substrate-binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 415.0
WH2_k127_4349289_1 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 384.0
WH2_k127_4402736_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.95e-217 677.0
WH2_k127_4402736_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 572.0
WH2_k127_4402736_2 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 379.0
WH2_k127_4402736_3 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 347.0
WH2_k127_4402736_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000376 131.0
WH2_k127_4405027_0 Outer membrane usher protein K07347 - - 2.838e-200 651.0
WH2_k127_4405027_1 metabolite transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 467.0
WH2_k127_4405027_2 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 388.0
WH2_k127_4405027_3 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001267 242.0
WH2_k127_4405027_4 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.00000000000000000000000000000000000000000000000001791 188.0
WH2_k127_4405027_5 Secreted protein - - - 0.000000000000000002988 90.0
WH2_k127_4405027_6 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000009346 68.0
WH2_k127_4405027_7 Spore Coat Protein U domain - - - 0.00002573 54.0
WH2_k127_4405027_8 PFAM General secretory system II protein E domain protein K11740 - - 0.000443 52.0
WH2_k127_4433933_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 2.995e-234 734.0
WH2_k127_4433933_1 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 500.0
WH2_k127_4433933_2 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 464.0
WH2_k127_4433933_3 abc transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 413.0
WH2_k127_4433933_4 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 362.0
WH2_k127_4433933_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 337.0
WH2_k127_4433933_6 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000002022 268.0
WH2_k127_4433933_7 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000517 237.0
WH2_k127_4542894_0 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 484.0
WH2_k127_4542894_1 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 473.0
WH2_k127_4542894_2 PFAM Dehydrogenase, E1 component K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 452.0
WH2_k127_4542894_3 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 433.0
WH2_k127_4542894_4 Rieske 2Fe-2S K00499 - 1.14.15.7 0.0000000000001996 69.0
WH2_k127_458153_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1500.0
WH2_k127_458153_1 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000005302 159.0
WH2_k127_4581983_0 RmuC family K09760 - - 1.611e-217 682.0
WH2_k127_4581983_1 thymidine phosphorylase K00758 - 2.4.2.4 3.044e-210 656.0
WH2_k127_4581983_2 coenzyme F390 synthetase - - - 3.882e-199 629.0
WH2_k127_4581983_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 576.0
WH2_k127_4581983_4 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 534.0
WH2_k127_4581983_5 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 479.0
WH2_k127_4581983_6 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 398.0
WH2_k127_4581983_7 COG1863 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.0000000000000000000000000000000000000000000000003886 180.0
WH2_k127_4581983_8 Multiple resistance and pH regulation protein F K05570 - - 0.000000002365 59.0
WH2_k127_45907_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1350.0
WH2_k127_45907_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 7.27e-269 831.0
WH2_k127_45907_2 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 289.0
WH2_k127_45907_3 Large family of predicted nucleotide-binding domains - - - 0.0000000000000006759 85.0
WH2_k127_4633896_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 580.0
WH2_k127_4633896_1 Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 269.0
WH2_k127_4633896_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000005821 127.0
WH2_k127_4659796_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 2046.0
WH2_k127_4659796_1 Histidine kinase - - - 1.947e-197 636.0
WH2_k127_4659796_2 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 630.0
WH2_k127_4659796_3 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 362.0
WH2_k127_4659796_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002498 269.0
WH2_k127_4659796_5 PFAM Tol-Pal system TolA K03646 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001403 269.0
WH2_k127_4659796_6 Mota tolq exbb proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000004838 208.0
WH2_k127_4659796_7 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000001672 206.0
WH2_k127_4659796_8 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000007913 209.0
WH2_k127_4659796_9 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000001556 154.0
WH2_k127_4673259_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1947.0
WH2_k127_4673259_1 TIGRFAM Formate dehydrogenase, gamma subunit K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 567.0
WH2_k127_4673259_2 two component, sigma54 specific, transcriptional regulator, Fis family K10126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 515.0
WH2_k127_4673259_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124,K07307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 448.0
WH2_k127_4673259_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 353.0
WH2_k127_4673259_5 - - - - 0.0000000000000000000002056 104.0
WH2_k127_4673259_6 - - - - 0.00000000000000000001636 97.0
WH2_k127_4673259_7 - - - - 0.00000000000003941 74.0
WH2_k127_4683632_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.216e-276 854.0
WH2_k127_4683632_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 518.0
WH2_k127_4683632_2 Histidine kinase K02484,K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 509.0
WH2_k127_4683632_3 PFAM helix-turn-helix protein RpiR K19337 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 505.0
WH2_k127_4683632_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 382.0
WH2_k127_4683632_5 Transcriptional regulatory protein, C terminal K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 359.0
WH2_k127_4683632_6 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 289.0
WH2_k127_4683632_7 Long-chain fatty acid--CoA ligase - - - 0.0000000000000000000000000000000000000000000000000003313 185.0
WH2_k127_4683632_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000005053 102.0
WH2_k127_4702087_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0 1102.0
WH2_k127_4702087_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 5.085e-206 644.0
WH2_k127_4702087_2 PFAM aminotransferase, class I and II - - - 1.441e-205 646.0
WH2_k127_4702087_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000515 276.0
WH2_k127_4702087_4 Mota tolq exbb proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002601 261.0
WH2_k127_4702087_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000004347 243.0
WH2_k127_4702087_6 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000000000000000002912 189.0
WH2_k127_4702087_7 - - - - 0.00000000000000000000000000000368 123.0
WH2_k127_4715229_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 292.0
WH2_k127_4715229_1 Trap dicarboxylate transporter, dctm subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007284 280.0
WH2_k127_4715229_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001657 278.0
WH2_k127_4715229_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006757 273.0
WH2_k127_4715229_4 Lysine exporter protein (Lyse ygga) K06895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003014 270.0
WH2_k127_4715229_5 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000001864 218.0
WH2_k127_4715229_6 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000002472 190.0
WH2_k127_4722270_0 PFAM TRAP dicarboxylate transporter- DctP subunit K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 513.0
WH2_k127_4722270_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 501.0
WH2_k127_4722270_2 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 402.0
WH2_k127_4722270_3 LysR substrate-binding K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 392.0
WH2_k127_4722270_4 PFAM Tripartite ATP-independent periplasmic - - - 0.000000000000000000000000000000000000000000000000000000000000000006542 230.0
WH2_k127_4774743_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 597.0
WH2_k127_4774743_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000004094 187.0
WH2_k127_4794062_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 2110.0
WH2_k127_4794062_1 AAA domain K02450,K12283 - - 4.41e-226 713.0
WH2_k127_4794062_10 Type II secretion system protein B K02451 - - 0.000000000000000000000000000000000000000005682 162.0
WH2_k127_4794062_11 nucleic acid-binding protein contains PIN domain K18828 - - 0.000000000000000000000000000000000003695 142.0
WH2_k127_4794062_12 SpoVT AbrB K18829 - - 0.00000000000000000000000000000002552 128.0
WH2_k127_4794062_13 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000000000005247 128.0
WH2_k127_4794062_14 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000002526 64.0
WH2_k127_4794062_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 418.0
WH2_k127_4794062_3 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 405.0
WH2_k127_4794062_4 PFAM ABC transporter related K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 404.0
WH2_k127_4794062_5 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 396.0
WH2_k127_4794062_6 TIGRFAM Phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 385.0
WH2_k127_4794062_7 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 339.0
WH2_k127_4794062_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001265 258.0
WH2_k127_4794062_9 Nucleotidyltransferase substrate binding protein like - - - 0.0000000000000000000000000000000000000000000000000001168 192.0
WH2_k127_480736_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 8.756e-304 938.0
WH2_k127_480736_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 560.0
WH2_k127_480736_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 347.0
WH2_k127_480736_3 PFAM RDD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005133 266.0
WH2_k127_480736_4 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000000000171 218.0
WH2_k127_480736_5 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000005114 90.0
WH2_k127_4868746_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 9.203e-254 788.0
WH2_k127_4868746_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 3.605e-197 616.0
WH2_k127_4885020_0 response regulator K02481 - - 1.805e-268 830.0
WH2_k127_4885020_1 Histidine kinase K02482 - 2.7.13.3 3.077e-242 758.0
WH2_k127_4885020_10 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000005917 63.0
WH2_k127_4885020_2 denitrification pathway - - - 3.725e-199 631.0
WH2_k127_4885020_3 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 575.0
WH2_k127_4885020_4 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 391.0
WH2_k127_4885020_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 375.0
WH2_k127_4885020_6 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000361 289.0
WH2_k127_4885020_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002816 252.0
WH2_k127_4885020_8 Pfam Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000107 210.0
WH2_k127_4885020_9 Pfam cytochrome c - - - 0.0000000000000000000000000000000000000000000009197 168.0
WH2_k127_4885402_0 PFAM carboxyl transferase K01969 - 6.4.1.4 1.441e-224 702.0
WH2_k127_4885402_1 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 492.0
WH2_k127_4887264_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1902494 3.1.11.5 6.395e-199 651.0
WH2_k127_4887264_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 0.000001395 51.0
WH2_k127_489601_0 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 380.0
WH2_k127_489601_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000004016 263.0
WH2_k127_489601_2 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000248 258.0
WH2_k127_489601_3 Redoxin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000007873 216.0
WH2_k127_489601_4 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000009065 181.0
WH2_k127_4919080_0 glutamate synthase, alpha subunit domain protein K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 9.234e-290 892.0
WH2_k127_4919080_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 456.0
WH2_k127_4919080_2 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 388.0
WH2_k127_4919080_3 Protein of unknown function (DUF1415) K09941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001236 269.0
WH2_k127_4919080_4 outer membrane lipoprotein K06077 - - 0.0000000000000000000000000000000000000000000000000001247 189.0
WH2_k127_4919080_5 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000003061 54.0
WH2_k127_4986852_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1532.0
WH2_k127_4986852_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000001838 108.0
WH2_k127_4995177_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000232 254.0
WH2_k127_4995177_1 PFAM SMP-30 Gluconolaconase K20952 - - 0.00000000000000000000000000001601 133.0
WH2_k127_5043939_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 567.0
WH2_k127_5043939_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 299.0
WH2_k127_5043939_2 Zinc-finger domain - - - 0.000000000000000000000000000000001169 130.0
WH2_k127_5044621_0 Adenylate cyclase K01768 - 4.6.1.1 6.331e-305 947.0
WH2_k127_5045353_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 3.398e-313 961.0
WH2_k127_5045353_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 3.695e-207 655.0
WH2_k127_5053711_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 558.0
WH2_k127_5053711_1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 419.0
WH2_k127_5053711_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 388.0
WH2_k127_5053711_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 340.0
WH2_k127_5053711_4 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 311.0
WH2_k127_5066027_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1579.0
WH2_k127_5066027_1 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 539.0
WH2_k127_5066027_2 Long-chain acyl-CoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 403.0
WH2_k127_5066027_3 Thermostable hemolysin - - - 0.00000000000000000000000000000000000000000000000000000000000159 216.0
WH2_k127_5066027_4 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000000000000000000000009323 191.0
WH2_k127_5066027_5 PFAM PsiF repeat protein - - - 0.000000000001874 71.0
WH2_k127_511667_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 6.931e-206 644.0
WH2_k127_511667_1 PFAM amine oxidase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 529.0
WH2_k127_511667_2 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000007115 237.0
WH2_k127_511667_3 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000006386 148.0
WH2_k127_5129109_0 hydrolase, family 3 K05349 - 3.2.1.21 8.801e-252 799.0
WH2_k127_5129109_1 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 456.0
WH2_k127_5129109_2 Glucuronate isomerase K01812 - 5.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
WH2_k127_5129109_3 LysR substrate binding domain K21757 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001013 271.0
WH2_k127_5130291_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 603.0
WH2_k127_5130291_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 535.0
WH2_k127_5130291_2 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 473.0
WH2_k127_5130291_3 Formyl transferase K00604 - 2.1.2.9 0.000000001964 59.0
WH2_k127_515960_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 9.696e-249 778.0
WH2_k127_515960_1 Mate efflux family protein K03327 - - 2.774e-206 652.0
WH2_k127_515960_2 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 418.0
WH2_k127_515960_3 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 398.0
WH2_k127_5161382_0 histidine kinase, dimerisation and phosphoacceptor region K07673 - 2.7.13.3 1.521e-308 957.0
WH2_k127_5161382_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 594.0
WH2_k127_5161382_2 PFAM NnrS family protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 470.0
WH2_k127_5161382_3 response regulator, receiver K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 340.0
WH2_k127_5161382_4 Cytochrome c oxidase subunit III K02164,K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003705 274.0
WH2_k127_5161382_5 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000000000000000000000000000246 226.0
WH2_k127_5161382_6 Protein of unknown function (DUF3079) - - - 0.0000000000000000000000001235 108.0
WH2_k127_5161382_7 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.000000000000000000005434 94.0
WH2_k127_5182970_0 carbohydrate phosphatase activity K01086 - 3.1.3.11,3.1.3.37 4.408e-206 644.0
WH2_k127_5182970_1 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 556.0
WH2_k127_5182970_2 Belongs to the transketolase family K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 483.0
WH2_k127_5182970_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 389.0
WH2_k127_5182970_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000001089 74.0
WH2_k127_5186566_0 PFAM CoA-binding domain protein K09181 - - 7.968e-313 966.0
WH2_k127_5186566_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 1.887e-200 631.0
WH2_k127_5186566_2 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 382.0
WH2_k127_5186566_3 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 314.0
WH2_k127_5186566_4 phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 306.0
WH2_k127_5186566_5 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000000000659 146.0
WH2_k127_5186566_6 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000004575 122.0
WH2_k127_5192912_0 Iron-sulfur cluster binding protein K18929 - - 3.404e-294 905.0
WH2_k127_5192912_1 Nlpbdapx family lipoprotein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 559.0
WH2_k127_5192912_2 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 414.0
WH2_k127_5192912_3 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 347.0
WH2_k127_5192912_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000009693 243.0
WH2_k127_5192912_5 Cysteine-rich domain protein K11473,K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000002455 227.0
WH2_k127_5207573_0 RNA binding S1 domain protein K06959 - - 0.0 1348.0
WH2_k127_5207573_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0 1021.0
WH2_k127_5207573_2 Circularly permuted ATP-grasp type 2 - - - 6.463e-251 775.0
WH2_k127_5207573_3 signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003586 266.0
WH2_k127_5207573_4 PFAM GCN5-related N-acetyltransferase K02348 - - 0.0000000000000000000000000000003322 124.0
WH2_k127_5231998_0 RND efflux system, outer membrane lipoprotein, NodT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 478.0
WH2_k127_5231998_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001595 280.0
WH2_k127_5231998_2 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.7.99.1 0.0000000000000000002103 91.0
WH2_k127_5241257_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.474e-277 856.0
WH2_k127_5241257_1 peptidase S1 and S6, chymotrypsin Hap K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 582.0
WH2_k127_5241257_10 Histidine triad (Hit) protein K02503 - - 0.000000000000000000000000000000000000000000000000000000000007625 217.0
WH2_k127_5241257_11 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000000000000000000000000003232 199.0
WH2_k127_5241257_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000000003526 117.0
WH2_k127_5241257_2 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 479.0
WH2_k127_5241257_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 422.0
WH2_k127_5241257_4 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 384.0
WH2_k127_5241257_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 359.0
WH2_k127_5241257_6 cytochrome c1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 336.0
WH2_k127_5241257_7 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000009314 252.0
WH2_k127_5241257_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000000000000000000000000000000009104 222.0
WH2_k127_5241257_9 membrane - - - 0.000000000000000000000000000000000000000000000000000000000002963 213.0
WH2_k127_5270082_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1693.0
WH2_k127_5270082_1 20S proteasome, A and B subunits K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 504.0
WH2_k127_5270082_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 470.0
WH2_k127_5270082_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000007976 184.0
WH2_k127_5270082_4 protein containing a NRPS condensation (Elongation) domain - - - 0.000000000000000000002579 108.0
WH2_k127_5271770_0 Phosphate acetyl butaryl transferase K00029 - 1.1.1.40 6.035e-289 894.0
WH2_k127_5271770_1 PFAM ABC transporter related K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 435.0
WH2_k127_5271770_2 ABC transporter, ATP-binding protein K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 413.0
WH2_k127_5271770_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 398.0
WH2_k127_5289326_0 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 487.0
WH2_k127_5289326_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009165 452.0
WH2_k127_5289326_2 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 336.0
WH2_k127_5289326_3 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 322.0
WH2_k127_5289326_4 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 322.0
WH2_k127_5293251_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 4.116e-206 643.0
WH2_k127_5293251_1 PFAM HI0933 family protein K07007 - - 6.681e-196 620.0
WH2_k127_5293251_2 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000006362 105.0
WH2_k127_5320012_0 PFAM aminotransferase, class I and II K14267 - 2.6.1.17 4.581e-224 698.0
WH2_k127_5320012_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 5.237e-204 636.0
WH2_k127_5320012_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 483.0
WH2_k127_5320012_3 PFAM Type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 420.0
WH2_k127_5320012_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 358.0
WH2_k127_5362690_0 Type II and III secretion system protein K02453 - - 4.361e-239 750.0
WH2_k127_5362690_1 PFAM General secretion pathway L K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 393.0
WH2_k127_5362690_2 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 335.0
WH2_k127_5362690_3 Type II secretion system (T2SS), protein N K02463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 330.0
WH2_k127_5362690_4 Prokaryotic N-terminal methylation motif K02459 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006865 283.0
WH2_k127_5362690_5 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001032 248.0
WH2_k127_5362690_6 General secretion pathway protein H K02457 - - 0.000000000000000000000000000000000000000000000000001096 188.0
WH2_k127_5362690_7 Type II secretion system (T2SS), protein I K02458 - - 0.000000000000000000000000000000000000000000000191 170.0
WH2_k127_5362690_8 Type II secretion system (T2SS), protein M K02462 - - 0.0000000000000000000000000000002916 130.0
WH2_k127_5428929_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1122.0
WH2_k127_5428929_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 427.0
WH2_k127_5428929_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001394 243.0
WH2_k127_5428929_3 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000000000000000000001879 113.0
WH2_k127_5446545_0 PFAM Major facilitator superfamily K02575 - - 9.779e-207 652.0
WH2_k127_5446545_1 TIGRFAM nitrate ABC transporter, ATPase subunits C and D K02049,K15578 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 464.0
WH2_k127_5446545_2 Gaf domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000312 260.0
WH2_k127_5453804_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0 1048.0
WH2_k127_5453804_1 DNA modification K07317 - 2.1.1.72 8.363e-281 900.0
WH2_k127_5453804_2 PFAM aminotransferase, class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 556.0
WH2_k127_5453804_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 493.0
WH2_k127_5453804_4 Histidine kinase K03406,K05875,K07647 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002532 267.0
WH2_k127_5459978_0 Integrase, catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 500.0
WH2_k127_5459978_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002942 271.0
WH2_k127_5459978_2 PFAM phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000003409 263.0
WH2_k127_5459978_3 PFAM phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001547 263.0
WH2_k127_5460041_0 Belongs to the ClpA ClpB family K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 564.0
WH2_k127_5460041_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 415.0
WH2_k127_5460041_2 PFAM regulatory protein TetR K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 306.0
WH2_k127_5460041_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 294.0
WH2_k127_5460041_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000004066 177.0
WH2_k127_5460041_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000001444 162.0
WH2_k127_5460496_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0 1041.0
WH2_k127_5460496_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 541.0
WH2_k127_5460496_2 PFAM MltA domain protein K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 526.0
WH2_k127_5460496_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000008802 236.0
WH2_k127_5460496_4 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000003086 190.0
WH2_k127_5460496_5 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000000000000002634 170.0
WH2_k127_5464776_0 PFAM ABC transporter related K10004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 402.0
WH2_k127_5464776_1 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K10002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 347.0
WH2_k127_5464776_2 Binding-protein-dependent transport system inner membrane component K10003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001065 263.0
WH2_k127_5464776_3 ATP synthase K02116 - - 0.00000000000000000000000000000000000000000001588 166.0
WH2_k127_5471126_0 Putative diguanylate phosphodiesterase - - - 2.413e-259 831.0
WH2_k127_5471126_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 8.177e-227 709.0
WH2_k127_5471126_10 Glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000209 246.0
WH2_k127_5471126_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003322 235.0
WH2_k127_5471126_12 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000000000000000000000004994 199.0
WH2_k127_5471126_13 Protein of unknown function (DUF3567) - - - 0.000000000000000000000000000000000000000000005864 164.0
WH2_k127_5471126_14 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000002584 119.0
WH2_k127_5471126_2 PFAM aminotransferase, class I and II K05825 - - 6.221e-213 669.0
WH2_k127_5471126_3 FIST N domain - - - 5.005e-208 653.0
WH2_k127_5471126_4 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 563.0
WH2_k127_5471126_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 475.0
WH2_k127_5471126_6 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 373.0
WH2_k127_5471126_7 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 323.0
WH2_k127_5471126_8 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 314.0
WH2_k127_5471126_9 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009708 306.0
WH2_k127_5486862_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0 1027.0
WH2_k127_5486862_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 1.876e-256 793.0
WH2_k127_5486862_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 526.0
WH2_k127_5486862_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 411.0
WH2_k127_5486862_4 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001242 253.0
WH2_k127_5486862_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000000000000000000003013 193.0
WH2_k127_5486862_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000000004846 127.0
WH2_k127_55266_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1138.0
WH2_k127_55266_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.908e-260 806.0
WH2_k127_55266_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 581.0
WH2_k127_55266_3 PFAM ATP-binding region, ATPase domain protein K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 561.0
WH2_k127_55266_4 Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 420.0
WH2_k127_55266_5 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 364.0
WH2_k127_55266_6 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 301.0
WH2_k127_55266_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000001265 222.0
WH2_k127_55266_8 - K06950 - - 0.000000001216 68.0
WH2_k127_5539406_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.4e-323 992.0
WH2_k127_5539406_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 592.0
WH2_k127_5539406_10 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000002557 149.0
WH2_k127_5539406_11 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000006782 139.0
WH2_k127_5539406_12 Protein of unknown function (DUF2909) - - - 0.00000000000000008691 83.0
WH2_k127_5539406_13 Protein of unknown function (DUF2970) - - - 0.0000000001835 64.0
WH2_k127_5539406_2 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 501.0
WH2_k127_5539406_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 390.0
WH2_k127_5539406_4 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 361.0
WH2_k127_5539406_5 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 303.0
WH2_k127_5539406_6 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001739 280.0
WH2_k127_5539406_7 Cytochrome c class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003358 277.0
WH2_k127_5539406_8 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005559 273.0
WH2_k127_5539406_9 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000000000000000000000002501 241.0
WH2_k127_5548757_0 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 509.0
WH2_k127_5548757_1 Mannitol dehydrogenase Rossmann domain K00040 - 1.1.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 453.0
WH2_k127_5548757_2 glucuronate isomerase K01812 - 5.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 301.0
WH2_k127_5558963_0 TIGRFAM arsenite-activated ATPase ArsA K01551 - 3.6.3.16 9.989e-216 677.0
WH2_k127_5558963_1 SMART regulatory protein, ArsR K03892 - - 0.0000000000000000000000000000000000000000000000000000000004352 202.0
WH2_k127_5558963_2 Arsenical resistance operon trans-acting repressor ArsD - - - 0.000000000000000000000000000000000000000000000000000000426 196.0
WH2_k127_5573_0 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 481.0
WH2_k127_5573_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 302.0
WH2_k127_5573_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000002142 215.0
WH2_k127_5585712_0 - - - - 8.515e-202 646.0
WH2_k127_5585712_1 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000006859 217.0
WH2_k127_5585712_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000904 77.0
WH2_k127_5594852_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 602.0
WH2_k127_5594852_1 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 353.0
WH2_k127_5594852_2 G T U mismatch-specific DNA glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000003702 250.0
WH2_k127_5594852_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000002789 152.0
WH2_k127_5594852_4 - - - - 0.00000000000000004602 90.0
WH2_k127_5598609_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1696.0
WH2_k127_5598609_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.414e-266 821.0
WH2_k127_5598609_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 426.0
WH2_k127_5598609_3 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003992 228.0
WH2_k127_5610733_0 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 2.885e-284 877.0
WH2_k127_5610733_1 6-phosphogluconate dehydrogenase, NAD-binding K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000002572 241.0
WH2_k127_5634190_0 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 377.0
WH2_k127_5634190_1 PIN domain K07062 - - 0.00000000000000000000000000000000000000000000000000000000000002368 216.0
WH2_k127_5634190_2 toxin-antitoxin pair type II binding - - - 0.00000000000000000000000001144 111.0
WH2_k127_566501_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 592.0
WH2_k127_566501_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 577.0
WH2_k127_566501_2 PFAM regulatory protein, LysR K21645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 529.0
WH2_k127_566501_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000616 241.0
WH2_k127_566501_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000005575 161.0
WH2_k127_566501_5 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00002609 49.0
WH2_k127_5709949_0 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 576.0
WH2_k127_5709949_1 EamA-like transporter family K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 497.0
WH2_k127_5709949_2 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001721 274.0
WH2_k127_5709949_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003402 257.0
WH2_k127_5709949_4 EamA-like transporter family - - - 0.000000000000000000000000000000004722 128.0
WH2_k127_572171_0 Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 567.0
WH2_k127_572171_1 Transport permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 474.0
WH2_k127_572171_2 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 332.0
WH2_k127_5754647_0 Peptidase M20 - - - 5.932e-284 876.0
WH2_k127_5754647_1 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 2.205e-208 651.0
WH2_k127_5754647_2 Trap dicarboxylate transporter, dctm subunit K21393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 519.0
WH2_k127_5754647_3 PFAM thioesterase superfamily protein K19222 - 3.1.2.28 0.00000000000000000000000000000000000000000000000000000000000000004145 228.0
WH2_k127_5754647_4 Single-strand binding protein family - - - 0.0003314 43.0
WH2_k127_5763812_0 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 8.835e-210 652.0
WH2_k127_5763812_1 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 419.0
WH2_k127_5763812_2 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 293.0
WH2_k127_5765470_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 491.0
WH2_k127_5765470_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 464.0
WH2_k127_5765470_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 414.0
WH2_k127_5765470_3 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 361.0
WH2_k127_5765470_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000004749 196.0
WH2_k127_5765470_5 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000003504 158.0
WH2_k127_5772982_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1002.0
WH2_k127_5772982_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.386e-294 906.0
WH2_k127_5772982_10 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000002809 221.0
WH2_k127_5772982_11 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000000000000000000000002884 174.0
WH2_k127_5772982_12 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000000000000149 158.0
WH2_k127_5772982_13 Protein of unknown function (DUF3579) - - - 0.000000000000000000000000000000000000002605 153.0
WH2_k127_5772982_14 Belongs to the UPF0125 (RnfH) family K03154,K09801 - - 0.00000000000000000000000001012 113.0
WH2_k127_5772982_15 Phage protein - - - 0.0000000000003774 72.0
WH2_k127_5772982_2 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 1.576e-224 701.0
WH2_k127_5772982_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 528.0
WH2_k127_5772982_4 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 498.0
WH2_k127_5772982_5 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 428.0
WH2_k127_5772982_6 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 397.0
WH2_k127_5772982_7 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 361.0
WH2_k127_5772982_8 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 299.0
WH2_k127_5772982_9 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000459 230.0
WH2_k127_5799263_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1147.0
WH2_k127_5799263_1 Dihydroorotate dehydrogenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 602.0
WH2_k127_5799263_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 498.0
WH2_k127_5799263_3 Two component transcriptional regulator, LuxR family K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 370.0
WH2_k127_5799263_4 PFAM ATP-binding region, ATPase domain protein K11711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001501 251.0
WH2_k127_5799263_5 PFAM Glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000000006265 206.0
WH2_k127_5830860_0 PFAM ABC transporter related K02056 - 3.6.3.17 5.003e-279 864.0
WH2_k127_5830860_1 CO dehydrogenase flavoprotein domain protein K13481 - 1.17.1.4 1.284e-196 623.0
WH2_k127_5830860_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 582.0
WH2_k127_5830860_3 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K13482 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 432.0
WH2_k127_5830860_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000181 216.0
WH2_k127_583611_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K12368 - - 1.182e-260 810.0
WH2_k127_583611_1 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 7.556e-195 611.0
WH2_k127_583611_10 Proline racemase K01777 - 5.1.1.4 0.000000000000000000000000000000000000000000000000111 178.0
WH2_k127_583611_11 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000002963 113.0
WH2_k127_583611_2 HI0933-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 591.0
WH2_k127_583611_3 Oligopeptide/dipeptide transporter, C-terminal region K12372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 569.0
WH2_k127_583611_4 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 551.0
WH2_k127_583611_5 FAD dependent oxidoreductase K21061 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 537.0
WH2_k127_583611_6 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 502.0
WH2_k127_583611_7 GntR domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 285.0
WH2_k127_583611_8 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005427 272.0
WH2_k127_583611_9 PFAM SWIB MDM2 domain protein - - - 0.00000000000000000000000000000000000000000000000000000008614 200.0
WH2_k127_586531_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 7.753e-226 706.0
WH2_k127_586531_1 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 378.0
WH2_k127_586531_2 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 355.0
WH2_k127_586531_3 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 297.0
WH2_k127_586531_4 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 282.0
WH2_k127_586531_5 Transcription regulator MerR DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000001863 218.0
WH2_k127_586531_6 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000002137 192.0
WH2_k127_5908587_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 1.012e-304 941.0
WH2_k127_5908587_1 HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 365.0
WH2_k127_5956884_0 belongs to the aldehyde dehydrogenase family K00130,K09472,K12254 - 1.2.1.54,1.2.1.8,1.2.1.99 8.226e-262 811.0
WH2_k127_5956884_1 PFAM binding-protein-dependent transport systems inner membrane component K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 489.0
WH2_k127_5956884_2 PFAM binding-protein-dependent transport systems inner membrane component K11075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 357.0
WH2_k127_5958546_0 Mannitol dehydrogenase rossman K00007 - 1.1.1.11 1.872e-209 655.0
WH2_k127_5958546_1 ABC transporter K10111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 574.0
WH2_k127_5958546_2 KR domain K00039 - 1.1.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 416.0
WH2_k127_5958546_3 PFAM binding-protein-dependent transport systems inner membrane component K10229,K17323 - - 0.0000000000000000000000000000001181 123.0
WH2_k127_598107_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0 1049.0
WH2_k127_598107_1 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 424.0
WH2_k127_598107_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 411.0
WH2_k127_598107_3 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 323.0
WH2_k127_598107_4 shape-determining protein K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001993 257.0
WH2_k127_598107_5 PFAM glucose-methanol-choline oxidoreductase K00108 - 1.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001596 252.0
WH2_k127_5989987_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1453.0
WH2_k127_603516_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 483.0
WH2_k127_603516_1 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 376.0
WH2_k127_603516_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 309.0
WH2_k127_603516_3 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000002753 248.0
WH2_k127_603516_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000001488 218.0
WH2_k127_603516_5 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000002965 128.0
WH2_k127_603516_6 Phosphopantetheine attachment site - - - 0.0000000000000000000000004602 106.0
WH2_k127_6109895_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 9.129e-319 980.0
WH2_k127_6109895_1 Outer membrane usher protein K07347 - - 4.815e-216 695.0
WH2_k127_6109895_2 PFAM HemY domain protein K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 482.0
WH2_k127_6109895_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 474.0
WH2_k127_6109895_4 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 391.0
WH2_k127_6109895_5 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000008958 266.0
WH2_k127_6109895_6 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.00000000000000000000000000000000000000000000000000000006413 204.0
WH2_k127_6109895_7 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000007849 158.0
WH2_k127_6109895_8 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000009087 129.0
WH2_k127_6109895_9 Spore Coat Protein U domain - - - 0.0000000000000000000005559 108.0
WH2_k127_6134547_0 PFAM acyl-CoA dehydrogenase domain protein K20035 - - 2.544e-280 866.0
WH2_k127_6134547_1 RNA-metabolising metallo-beta-lactamase K07576 - - 1.114e-250 778.0
WH2_k127_6134547_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 6.849e-208 648.0
WH2_k127_6134547_3 Rhodanese Homology Domain K07146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 485.0
WH2_k127_6134547_4 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005563 241.0
WH2_k127_6159111_0 Transposase IS116 IS110 IS902 family protein - - - 5.57e-200 629.0
WH2_k127_6159111_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 329.0
WH2_k127_6159111_2 Transposase - - - 0.000000000000000000001225 94.0
WH2_k127_6159111_3 Cytochrome c554 and c-prime - - - 0.00000003649 63.0
WH2_k127_6206971_0 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 403.0
WH2_k127_6206971_1 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 362.0
WH2_k127_6206971_2 Phasin protein - - - 0.000000000000000000000000000000000000000002032 162.0
WH2_k127_6206971_3 - - - - 0.00000000000000000000000000000000000006317 146.0
WH2_k127_6206971_4 - - - - 0.00000000000000000000000000000000000006928 143.0
WH2_k127_6206971_5 - - - - 0.000000000000000009478 86.0
WH2_k127_6206971_6 VanZ like family - - - 0.000000000007223 70.0
WH2_k127_6206971_7 VanZ like family - - - 0.00000000001001 66.0
WH2_k127_6206971_8 - - - - 0.000000001665 59.0
WH2_k127_623833_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 8.806e-245 760.0
WH2_k127_623833_1 Domain of unknown function (DUF4143) K07133 - - 2.449e-221 689.0
WH2_k127_623833_2 Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 565.0
WH2_k127_623833_3 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 374.0
WH2_k127_623833_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 351.0
WH2_k127_6255017_0 General secretory system II, protein E domain protein K02454,K02652,K12276 - - 0.0 1014.0
WH2_k127_6255017_1 Chromate transporter K07240 - - 1.621e-256 796.0
WH2_k127_6255017_2 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 427.0
WH2_k127_6255017_3 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 289.0
WH2_k127_6255017_4 Chromate resistance - - - 0.000000000000000000000000000000000000000000000000000000000003487 209.0
WH2_k127_6259425_0 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 502.0
WH2_k127_6259425_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 374.0
WH2_k127_6259425_2 threonine dehydrogenase and related Zn-dependent dehydrogenases K00098 - 1.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 314.0
WH2_k127_6259425_3 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000427 287.0
WH2_k127_6261409_0 Cysteine-rich domain protein K11473,K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 491.0
WH2_k127_6261409_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 469.0
WH2_k127_6261409_2 TIGRFAM phasin family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000138 254.0
WH2_k127_6277769_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 555.0
WH2_k127_6277769_1 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 314.0
WH2_k127_6277769_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002183 264.0
WH2_k127_6277769_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000001488 236.0
WH2_k127_6277769_4 Belongs to the transcriptional regulatory Fis family K03557 - - 0.00000000000000000000000000007321 117.0
WH2_k127_6286006_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 608.0
WH2_k127_6286006_1 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 380.0
WH2_k127_6286006_2 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 363.0
WH2_k127_6286006_3 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000000000000000000000002661 183.0
WH2_k127_6286006_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000002502 88.0
WH2_k127_6300215_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 5.828e-273 851.0
WH2_k127_6300215_1 OmpA-like transmembrane domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006751 228.0
WH2_k127_6300215_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000000000000009102 207.0
WH2_k127_6300215_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000001056 205.0
WH2_k127_6300215_4 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000000000000000000000000016 168.0
WH2_k127_6300215_5 Domain of unknown function (DUF1508) K09946 GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000002702 137.0
WH2_k127_6300215_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000007438 57.0
WH2_k127_6315268_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 1.867e-199 628.0
WH2_k127_6315268_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 2.05e-199 626.0
WH2_k127_6315268_2 Mg2 transporter protein cora family protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 536.0
WH2_k127_6315268_3 PFAM VanZ family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 488.0
WH2_k127_6315268_4 PFAM Multiple antibiotic resistance (MarC)-related K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005602 287.0
WH2_k127_6315268_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001573 245.0
WH2_k127_6315268_6 PFAM conserved K08973 - - 0.000000000000000000000000000000000000000000000000000000000000000000001088 238.0
WH2_k127_6315268_7 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000002251 199.0
WH2_k127_6315268_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000003005 66.0
WH2_k127_6333105_0 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 547.0
WH2_k127_6333105_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K22024 - 1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 466.0
WH2_k127_6333105_2 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 334.0
WH2_k127_6333105_3 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 297.0
WH2_k127_6333105_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001904 278.0
WH2_k127_6333105_5 Protein conserved in bacteria K22129 - 2.7.1.219,2.7.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000001699 252.0
WH2_k127_6333105_6 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000001934 217.0
WH2_k127_6349104_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 4.962e-306 944.0
WH2_k127_6349104_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.858e-247 775.0
WH2_k127_6349104_2 Belongs to the methyltransferase superfamily K07444 - - 2.74e-206 647.0
WH2_k127_6349104_3 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 430.0
WH2_k127_6349104_4 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 287.0
WH2_k127_6349104_5 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001606 249.0
WH2_k127_6349104_6 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002086 244.0
WH2_k127_6375654_0 Cellulose biosynthesis protein BcsQ K02282 - - 0.00000000000000000000000000000000000000000002671 176.0
WH2_k127_6375654_1 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000007304 151.0
WH2_k127_6375654_2 TadE-like protein - - - 0.0000000000000000000000000000000000001164 147.0
WH2_k127_6375654_3 PFAM TadE family protein - - - 0.0000000000000000000000000000000000008517 147.0
WH2_k127_6377218_0 PFAM phosphoadenosine phosphosulfate reductase K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 445.0
WH2_k127_6377218_1 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 421.0
WH2_k127_6377218_2 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein K00381,K00392 - 1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 359.0
WH2_k127_6377218_3 PFAM Uncharacterised conserved protein UCP030820 - - - 0.00000000000000000000000000000000000000001464 160.0
WH2_k127_6381963_0 MacB-like periplasmic core domain K02004 - - 1.299e-198 624.0
WH2_k127_6381963_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 436.0
WH2_k127_6381963_2 oxygen carrier activity K07216 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 399.0
WH2_k127_6381963_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 310.0
WH2_k127_6381963_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000001274 229.0
WH2_k127_6381963_5 Belongs to the UPF0502 family K09915 - - 0.0000000000000000002762 88.0
WH2_k127_6385828_0 PFAM carbon starvation protein CstA K06200 - - 9.845e-211 657.0
WH2_k127_6385828_1 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 383.0
WH2_k127_6385828_2 Histidine kinase K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001312 225.0
WH2_k127_6392173_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 7.958e-248 781.0
WH2_k127_6392173_1 Pfam:HipA_N K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 570.0
WH2_k127_6392173_2 Ethylbenzene dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 472.0
WH2_k127_6392173_3 Amino-transferase class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 354.0
WH2_k127_6392173_4 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 331.0
WH2_k127_6392173_5 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000002586 138.0
WH2_k127_6424248_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1767.0
WH2_k127_6424248_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 2.995e-252 781.0
WH2_k127_6501362_0 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 481.0
WH2_k127_6501362_1 Protein of unknown function (DUF455) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 317.0
WH2_k127_6501362_2 Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003867 264.0
WH2_k127_6522429_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1230.0
WH2_k127_6522429_1 zinc metalloprotease K11749 - - 6.975e-194 614.0
WH2_k127_6522429_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000007865 227.0
WH2_k127_6522429_3 Belongs to the skp family K06142 - - 0.000000000000000001135 88.0
WH2_k127_6552175_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 491.0
WH2_k127_6552175_1 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds K01666,K18365 - 4.1.3.39,4.1.3.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 469.0
WH2_k127_6552175_2 Thioesterase K01075 - 3.1.2.23 0.0000000000000000000000000000000000000000000000000000002963 202.0
WH2_k127_6552175_3 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000001679 133.0
WH2_k127_6562433_0 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 514.0
WH2_k127_6562433_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 316.0
WH2_k127_6562433_2 PFAM Xanthine uracil vitamin C permease K02824 - - 0.000000000000000000000000000000000000000000000000000000003687 200.0
WH2_k127_6564598_0 PFAM peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 618.0
WH2_k127_6564598_1 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000007929 164.0
WH2_k127_6580225_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1232.0
WH2_k127_6580225_1 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1200.0
WH2_k127_6580225_10 PFAM peptidylprolyl isomerase FKBP-type K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000001091 212.0
WH2_k127_6580225_2 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.0 1056.0
WH2_k127_6580225_3 Extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 572.0
WH2_k127_6580225_4 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 542.0
WH2_k127_6580225_5 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 521.0
WH2_k127_6580225_6 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 499.0
WH2_k127_6580225_7 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 400.0
WH2_k127_6580225_8 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000004704 224.0
WH2_k127_6580225_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000004602 220.0
WH2_k127_6604894_0 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 595.0
WH2_k127_6604894_1 Involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 348.0
WH2_k127_6604894_2 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 314.0
WH2_k127_6604894_3 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001715 250.0
WH2_k127_6604894_4 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000000000001381 185.0
WH2_k127_6604894_5 - - - - 0.00000000000000000000000000000000000008374 145.0
WH2_k127_6629135_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 4.613e-216 674.0
WH2_k127_6629135_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 6.198e-202 633.0
WH2_k127_6629135_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 368.0
WH2_k127_6629135_3 CNP1-like family - - - 0.00000000000000000000000000000000000000000000000001666 187.0
WH2_k127_6668932_0 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009281 557.0
WH2_k127_6668932_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 534.0
WH2_k127_6668932_2 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 434.0
WH2_k127_6668932_3 Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 387.0
WH2_k127_6668932_4 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000000000000000000001204 254.0
WH2_k127_6668932_5 PFAM BLUF domain protein - - - 0.00000001942 56.0
WH2_k127_669913_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1182.0
WH2_k127_6712571_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 531.0
WH2_k127_6712571_1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 330.0
WH2_k127_6712571_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000001741 231.0
WH2_k127_6712571_3 DNA-binding protein VF530 - - - 0.00000000000000000000001091 100.0
WH2_k127_6712571_4 4Fe-4S binding domain - - - 0.0000000000000000001688 93.0
WH2_k127_6716163_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.317e-294 904.0
WH2_k127_6716163_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 328.0
WH2_k127_6720443_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 470.0
WH2_k127_6720443_1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 394.0
WH2_k127_6720443_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 368.0
WH2_k127_6720443_3 flavodoxin nitric oxide synthase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 305.0
WH2_k127_6720443_4 PFAM FAD dependent oxidoreductase K06955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005679 245.0
WH2_k127_6752693_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001648 277.0
WH2_k127_6752693_1 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001144 252.0
WH2_k127_687271_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 2.056e-219 698.0
WH2_k127_687271_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process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
WH2_k127_687271_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 544.0
WH2_k127_687271_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 297.0
WH2_k127_687271_4 Tetratricopeptide repeat K02200 - - 0.00000000000000000000000006016 118.0
WH2_k127_688121_0 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 406.0
WH2_k127_688121_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002036 266.0
WH2_k127_688121_2 Haem-degrading K11477 - - 0.00000000000000000000000000000000000000000000000000000000000000003103 227.0
WH2_k127_688121_3 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000000000000001995 152.0
WH2_k127_6883069_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.387e-220 691.0
WH2_k127_6883069_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 486.0
WH2_k127_6883069_2 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 327.0
WH2_k127_6883580_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 3.561e-201 636.0
WH2_k127_6883580_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 489.0
WH2_k127_6883580_2 PFAM permease YjgP YjgQ family protein K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 472.0
WH2_k127_6883580_3 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000003286 88.0
WH2_k127_6903047_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.957e-312 962.0
WH2_k127_6903047_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 3.25e-277 861.0
WH2_k127_6903047_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 4.634e-243 757.0
WH2_k127_6903047_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 2.11e-202 636.0
WH2_k127_6903047_4 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000001215 234.0
WH2_k127_6919589_0 Signal transduction histidine kinase - - - 0.0 1062.0
WH2_k127_6919589_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 546.0
WH2_k127_6919589_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 337.0
WH2_k127_6919589_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000001335 212.0
WH2_k127_6919589_4 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000000000000000000000002535 220.0
WH2_k127_6919589_5 Protein of unknown function (DUF3800) - - - 0.000000000000000000000000000000000000000003658 161.0
WH2_k127_6919589_6 Phage integrase family - - - 0.0000000009741 60.0
WH2_k127_6919589_7 - - - - 0.0000001623 53.0
WH2_k127_694980_0 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 477.0
WH2_k127_694980_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 424.0
WH2_k127_694980_2 Amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 367.0
WH2_k127_694980_3 FCD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 330.0
WH2_k127_694980_4 KR domain K18333 - - 0.00000000000000000000000000000000000000000009485 161.0
WH2_k127_694980_5 Belongs to the RbsD FucU family K02431 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0030246,GO:0036094,GO:0042806,GO:0044238,GO:0044281,GO:0048029,GO:0071704 5.1.3.29 0.0000000000000000000000000007302 116.0
WH2_k127_694980_6 fucose binding K02431 GO:0000003,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0007275,GO:0007399,GO:0007610,GO:0007617,GO:0007618,GO:0008150,GO:0008152,GO:0009987,GO:0010721,GO:0016853,GO:0016854,GO:0016857,GO:0019098,GO:0019318,GO:0019953,GO:0022008,GO:0022414,GO:0030154,GO:0030246,GO:0032501,GO:0032502,GO:0032504,GO:0036065,GO:0036094,GO:0042806,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0048029,GO:0048519,GO:0048523,GO:0048609,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051239,GO:0051241,GO:0051704,GO:0051960,GO:0051961,GO:0060180,GO:0060284,GO:0065007,GO:0070085,GO:0071704,GO:2000026 5.1.3.29 0.00000002786 55.0
WH2_k127_7031798_0 PFAM isocitrate isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 7.273e-211 659.0
WH2_k127_7031798_1 PFAM isocitrate isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 1.846e-208 652.0
WH2_k127_7031798_2 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 580.0
WH2_k127_7031798_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 557.0
WH2_k127_7031798_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 376.0
WH2_k127_7031798_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000000000000000000000000000000000000000001002 226.0
WH2_k127_7031798_6 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000006667 155.0
WH2_k127_7031798_7 - - - - 0.0000000000000000000002508 98.0
WH2_k127_7054553_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 8.495e-250 777.0
WH2_k127_7054553_1 Peptidoglycan polymerase that is essential for cell division K03588 - - 3.504e-205 642.0
WH2_k127_7054553_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 557.0
WH2_k127_7054553_3 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 474.0
WH2_k127_7054553_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 322.0
WH2_k127_7054553_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000001125 70.0
WH2_k127_7065165_0 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 388.0
WH2_k127_7065165_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 338.0
WH2_k127_7065165_2 - - - - 0.000000000000000000000000000000000000000000000000001888 187.0
WH2_k127_7079443_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 5.935e-219 688.0
WH2_k127_7079443_1 PFAM Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 474.0
WH2_k127_7079443_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000005681 224.0
WH2_k127_7094391_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002786 233.0
WH2_k127_7094391_1 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000008438 223.0
WH2_k127_7094391_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000031 102.0
WH2_k127_7094391_3 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000007621 82.0
WH2_k127_7176405_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K21393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 574.0
WH2_k127_7176405_1 Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 494.0
WH2_k127_7176405_2 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 463.0
WH2_k127_7176405_3 Shikimate dehydrogenase substrate binding domain protein K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 443.0
WH2_k127_7176405_4 auxin efflux carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 332.0
WH2_k127_7176405_5 Tripartite ATP-independent periplasmic transporter dctq component K21394 - - 0.00000000000000000000000000000000000000000000000005677 184.0
WH2_k127_7176405_6 PFAM regulatory protein TetR - - - 0.0000000000000000000001714 97.0
WH2_k127_7176405_7 Thioesterase superfamily protein - - - 0.00000000000000000002262 90.0
WH2_k127_7192986_0 FtsX-like permease family K02004 - - 2.01e-202 634.0
WH2_k127_7192986_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 489.0
WH2_k127_7225827_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 578.0
WH2_k127_7225827_1 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 404.0
WH2_k127_7225827_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 297.0
WH2_k127_7225827_3 Belongs to the UPF0502 family K09915 - - 0.000000000000000002371 86.0
WH2_k127_732713_0 Transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 564.0
WH2_k127_732713_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 368.0
WH2_k127_732713_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000008797 203.0
WH2_k127_732713_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000001214 172.0
WH2_k127_7329558_0 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 473.0
WH2_k127_7329558_1 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 423.0
WH2_k127_7329558_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 323.0
WH2_k127_7329558_3 PFAM Ankyrin K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 301.0
WH2_k127_7329558_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000004304 188.0
WH2_k127_7381082_0 TIGRFAM methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.731e-302 930.0
WH2_k127_7381082_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 9.886e-252 782.0
WH2_k127_7381082_2 Transcriptional regulator, LysR family K21699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 486.0
WH2_k127_7381082_3 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000001037 221.0
WH2_k127_7382240_0 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 7.878e-298 919.0
WH2_k127_7382240_1 SMP-30 Gluconolaconase LRE domain protein K13874,K14274 - 3.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 475.0
WH2_k127_7385118_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 493.0
WH2_k127_7385118_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 383.0
WH2_k127_7385118_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 337.0
WH2_k127_7385118_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 319.0
WH2_k127_7385118_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000009398 197.0
WH2_k127_7385118_5 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000000000000000002575 157.0
WH2_k127_7410976_0 PFAM transglutaminase domain protein K22452 - 2.3.2.13 1.569e-301 937.0
WH2_k127_7410976_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 567.0
WH2_k127_7410976_2 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 534.0
WH2_k127_7410976_3 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 511.0
WH2_k127_7410976_4 lytic murein transglycosylase B K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 480.0
WH2_k127_7410976_5 Circularly permuted ATP-grasp type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 435.0
WH2_k127_7410976_6 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 409.0
WH2_k127_7410976_7 PFAM MscS Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 346.0
WH2_k127_7410976_8 PFAM MscS Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000005706 219.0
WH2_k127_7419077_0 General secretory system II, protein E domain protein K02454,K02652 - - 4.81e-294 917.0
WH2_k127_7419077_1 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 3.13e-251 784.0
WH2_k127_7419077_2 Aldo/keto reductase family K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 326.0
WH2_k127_7531362_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1394.0
WH2_k127_7531362_1 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 571.0
WH2_k127_7545038_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.624e-232 725.0
WH2_k127_7545038_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 332.0
WH2_k127_7545038_2 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004469 279.0
WH2_k127_7545038_3 STAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002972 273.0
WH2_k127_7545038_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000172 120.0
WH2_k127_7588000_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 621.0
WH2_k127_7588000_1 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 604.0
WH2_k127_7588000_2 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 531.0
WH2_k127_7588000_3 PFAM CHAD domain containing protein K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 494.0
WH2_k127_7588000_4 PFAM Phosphoglycerate mutase K08296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008597 243.0
WH2_k127_76021_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 518.0
WH2_k127_76021_1 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 448.0
WH2_k127_76021_2 Trap-type c4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000003973 205.0
WH2_k127_76021_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.00000000000000000000000000000000000000000000000002308 181.0
WH2_k127_7619441_0 binding-protein-dependent transport systems inner membrane component K02011 - - 2.533e-257 802.0
WH2_k127_7619441_1 Conserved carboxylase domain K03416 - 2.1.3.1 9.906e-233 726.0
WH2_k127_7619441_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 579.0
WH2_k127_7619441_3 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000108 278.0
WH2_k127_7619441_4 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001386 265.0
WH2_k127_7619441_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000001143 153.0
WH2_k127_7619441_6 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000008284 131.0
WH2_k127_7619441_7 Sulphur transport K07112 - - 0.0000000000000003815 79.0
WH2_k127_7640671_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1737.0
WH2_k127_7640671_1 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 2.303e-227 706.0
WH2_k127_7640671_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00002812 46.0
WH2_k127_7758936_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 2.197e-266 835.0
WH2_k127_7758936_1 Bacterial extracellular solute-binding protein K17241 - - 2.737e-218 686.0
WH2_k127_7758936_2 ABC-type sugar transport systems permease components K02025,K05814,K10118,K17242,K17245 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 518.0
WH2_k127_7758936_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 375.0
WH2_k127_7758936_4 helix_turn _helix lactose operon repressor K02529,K06145 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 355.0
WH2_k127_7758936_5 Enoyl-(Acyl carrier protein) reductase K22185 - 1.1.1.175 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 349.0
WH2_k127_7758936_6 LacI family K06145 - - 0.000000000000000000000000000000000000000000000000000000000000000000002057 249.0
WH2_k127_7758936_7 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000008832 166.0
WH2_k127_7758936_8 Acetyl xylan esterase domain-containing protein - - - 0.00000000000000000000000000000000000000001357 167.0
WH2_k127_7758936_9 PFAM binding-protein-dependent transport systems inner membrane component K02026,K17243 - - 0.0000000000000003054 79.0
WH2_k127_7772197_0 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002645 258.0
WH2_k127_7772197_1 OmpA family - - - 0.00000000000000000000000000000000000000000001835 170.0
WH2_k127_7772197_2 FecR protein - - - 0.000000000000000000000000000000000000003536 151.0
WH2_k127_7772197_3 Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.00000000000000000000002147 107.0
WH2_k127_7772197_4 Histidine kinase-like ATPase domain - - - 0.000000000002001 78.0
WH2_k127_7772197_5 Flp pilus assembly protein, pilin Flp K02651 - - 0.00000000009672 64.0
WH2_k127_7772197_6 Beta-lactamase superfamily domain - - - 0.00000003595 56.0
WH2_k127_7772197_7 Flp/Fap pilin component K02651 - - 0.000004853 51.0
WH2_k127_7785313_0 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.0 1063.0
WH2_k127_7785313_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 3.461e-260 807.0
WH2_k127_7785313_10 PFAM Cytochrome c, class I K08738 - - 0.0000000000000000000000000000000000001118 147.0
WH2_k127_7785313_11 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000001535 117.0
WH2_k127_7785313_12 - - - - 0.00000000000000000000000004137 109.0
WH2_k127_7785313_13 FixH K09926 - - 0.00000000000000000187 87.0
WH2_k127_7785313_14 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.00000000000000002331 81.0
WH2_k127_7785313_15 PFAM Cbb3-type cytochrome oxidase component K00407 - - 0.00000000000000003043 85.0
WH2_k127_7785313_2 PFAM AMP-dependent synthetase and ligase K18661 - - 8.652e-253 788.0
WH2_k127_7785313_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 559.0
WH2_k127_7785313_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 506.0
WH2_k127_7785313_5 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 489.0
WH2_k127_7785313_6 Transcriptional regulator crp fnr family K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 405.0
WH2_k127_7785313_7 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 342.0
WH2_k127_7785313_8 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 323.0
WH2_k127_7785313_9 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001671 233.0
WH2_k127_7789609_0 TIGRFAM methionine aminopeptidase, type I K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 504.0
WH2_k127_7789609_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000145 255.0
WH2_k127_7789609_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0000639 48.0
WH2_k127_7824724_0 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09970 - - 2.69e-215 672.0
WH2_k127_7824724_1 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 582.0
WH2_k127_7824724_2 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 431.0
WH2_k127_7830372_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138,K18307 - - 0.0 1377.0
WH2_k127_7830372_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 383.0
WH2_k127_7830372_2 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 368.0
WH2_k127_7830372_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 283.0
WH2_k127_7830372_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003705 274.0
WH2_k127_7830372_5 Domain of unknown function (DUF4398) - - - 0.000000000000000000000000006816 117.0
WH2_k127_7830437_0 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 6.816e-276 860.0
WH2_k127_7830437_1 peptidase dimerisation domain protein - - - 4.785e-213 666.0
WH2_k127_7830437_2 Phosphate acetyl butaryl transferase K00029 - 1.1.1.40 0.000000000000000000000000000000000000000000000000000000000006963 208.0
WH2_k127_7830437_3 PFAM Polysaccharide deacetylase K01452 - 3.5.1.41 0.0000000000000000000000000000000000000000000000000000000006908 201.0
WH2_k127_789205_0 Bacterial extracellular solute-binding protein K02055 - - 7.454e-261 808.0
WH2_k127_789205_1 Belongs to the ABC transporter superfamily K02052,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 560.0
WH2_k127_789205_2 binding-protein-dependent transport systems inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 526.0
WH2_k127_789205_3 binding-protein-dependent transport systems inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 514.0
WH2_k127_7905291_0 AMP-binding enzyme K01895 - 6.2.1.1 3.279e-250 791.0
WH2_k127_7905291_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 458.0
WH2_k127_7915723_0 Alcohol dehydrogenase zinc-binding domain protein K00098 - 1.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 587.0
WH2_k127_7915723_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K21393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 456.0
WH2_k127_7915723_2 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 426.0
WH2_k127_7915723_3 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 404.0
WH2_k127_7915723_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 376.0
WH2_k127_7915723_5 Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000001958 192.0
WH2_k127_7948844_0 Double sensory domain of two-component sensor kinase - - - 8.483e-252 790.0
WH2_k127_7948844_1 response regulator K07714 - - 1.482e-227 711.0
WH2_k127_7948844_2 helix-turn-helix, Fis-type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 556.0
WH2_k127_7948844_3 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 311.0
WH2_k127_7948844_4 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005573 274.0
WH2_k127_7948844_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000001427 140.0
WH2_k127_7948844_6 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000006486 91.0
WH2_k127_795434_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1044.0
WH2_k127_795434_1 PFAM cytochrome c biogenesis protein, transmembrane region K04084,K08344 - 1.8.1.8 1.06e-298 932.0
WH2_k127_795434_10 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 381.0
WH2_k127_795434_11 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 335.0
WH2_k127_795434_12 Electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 310.0
WH2_k127_795434_13 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 261.0
WH2_k127_795434_14 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000000000000003066 255.0
WH2_k127_795434_15 Alkylphosphonate utilization operon protein K06193 - - 0.00000000000000000000000000000000000000000000000000000000001022 211.0
WH2_k127_795434_16 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000001293 191.0
WH2_k127_795434_17 Uncharacterised ACR, YggU family COG1872 K09131 - - 0.00000000000000000000000000000000000000000000009753 172.0
WH2_k127_795434_18 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000006112 116.0
WH2_k127_795434_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 1.628e-209 659.0
WH2_k127_795434_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 526.0
WH2_k127_795434_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 510.0
WH2_k127_795434_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 457.0
WH2_k127_795434_6 PFAM Glutamine amidotransferase, class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 459.0
WH2_k127_795434_7 Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 451.0
WH2_k127_795434_8 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 449.0
WH2_k127_795434_9 PFAM Creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 428.0
WH2_k127_7990006_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 342.0
WH2_k127_7990006_1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 306.0
WH2_k127_7990006_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 288.0
WH2_k127_7990006_3 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003375 246.0
WH2_k127_7990006_4 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000000000000000000000000006794 174.0
WH2_k127_801663_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1390.0
WH2_k127_801663_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0 1099.0
WH2_k127_801663_10 PFAM YaeQ family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 346.0
WH2_k127_801663_11 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 337.0
WH2_k127_801663_12 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000001911 262.0
WH2_k127_801663_13 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000002825 258.0
WH2_k127_801663_14 Protein of unknown function (DUF3717) K06938 - - 0.00000000000000000000000000000000000000000000000000000000000005464 216.0
WH2_k127_801663_15 PFAM Membrane protein of K08972 - - 0.0000000000000000000000000000000000000000000004949 169.0
WH2_k127_801663_16 cytochrome - - - 0.000000000000000000000000000000000000000005288 165.0
WH2_k127_801663_17 HutD K09975 - - 0.0000000000000000000000000000000000000004107 157.0
WH2_k127_801663_18 Protein of unknown function - - - 0.00000000000000000000001001 101.0
WH2_k127_801663_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.266e-272 844.0
WH2_k127_801663_3 Histidine ammonia-lyase K01745 - 4.3.1.3 8.657e-257 799.0
WH2_k127_801663_4 TIGRFAM Imidazolonepropionase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 599.0
WH2_k127_801663_5 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 581.0
WH2_k127_801663_6 Nucleoside recognition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 536.0
WH2_k127_801663_7 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 430.0
WH2_k127_801663_8 Arginase family K01479 - 3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 415.0
WH2_k127_801663_9 TIGRFAM histidine utilization repressor K05836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 372.0
WH2_k127_8027368_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.092e-250 776.0
WH2_k127_8027368_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 364.0
WH2_k127_8027368_2 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 349.0
WH2_k127_8029647_0 TIGRFAM nitrogen regulation protein NR(I) K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 7.747e-255 794.0
WH2_k127_8029647_1 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 573.0
WH2_k127_8029647_2 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 368.0
WH2_k127_8029647_3 - - - - 0.000000000000000000000000000000000000000000000000000001146 196.0
WH2_k127_8029647_4 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000002578 105.0
WH2_k127_8038494_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 6.661e-318 978.0
WH2_k127_8038494_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 394.0
WH2_k127_804199_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 595.0
WH2_k127_804199_1 Belongs to the protein N5-glutamine methyltransferase family K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 424.0
WH2_k127_804199_2 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 327.0
WH2_k127_804199_3 PFAM Type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009098 256.0
WH2_k127_8052882_0 transposase IS116 IS110 IS902 family protein - - - 9.831e-208 647.0
WH2_k127_8052882_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 567.0
WH2_k127_8052882_2 Transposase IS116 IS110 IS902 family protein K07486 - - 0.0000001197 55.0
WH2_k127_8112820_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.442e-310 962.0
WH2_k127_8112820_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 361.0
WH2_k127_8148349_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 5.979e-270 836.0
WH2_k127_8148349_1 Belongs to the DEAD box helicase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 566.0
WH2_k127_8148349_2 WLM domain K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004948 261.0
WH2_k127_8148349_3 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000005614 217.0
WH2_k127_8148349_4 - - - - 0.0000000000000000000000000000000000000000000000000129 184.0
WH2_k127_8148349_5 - - - - 0.00000000000000000000000000000000000001435 148.0
WH2_k127_8219705_0 TonB-dependent receptor plug K16090 - - 2.5e-323 1007.0
WH2_k127_8219705_1 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds K01666,K18365 - 4.1.3.39,4.1.3.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 598.0
WH2_k127_8219705_10 Hemin uptake protein - - - 0.0002039 48.0
WH2_k127_8219705_2 Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds K04073,K18366 - 1.2.1.10,1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 582.0
WH2_k127_8219705_3 PFAM extracellular solute-binding protein family 1 K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 421.0
WH2_k127_8219705_4 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 399.0
WH2_k127_8219705_5 Protein of unknown function (DUF1513) K09947 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 359.0
WH2_k127_8219705_6 Mota tolq exbb proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 317.0
WH2_k127_8219705_7 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000005789 175.0
WH2_k127_8219705_8 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000006677 152.0
WH2_k127_8219705_9 PFAM FAD linked oxidase domain protein - - - 0.000002238 51.0
WH2_k127_8275966_0 carbohydrate binding K13688 - - 2.724e-280 887.0
WH2_k127_8275966_1 OmpA-like transmembrane domain K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 512.0
WH2_k127_8275966_2 domain protein K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 368.0
WH2_k127_8275966_3 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 353.0
WH2_k127_8275966_4 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000375 262.0
WH2_k127_8275966_5 Cadherin-like beta sandwich domain - - - 0.0000001401 64.0
WH2_k127_8285316_0 PFAM PHB de-polymerase domain protein K05973 - 3.1.1.75 1.562e-244 764.0
WH2_k127_8285316_1 PFAM aminotransferase, class I and II K00832 - 2.6.1.57 2.138e-239 743.0
WH2_k127_8285316_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 579.0
WH2_k127_8285316_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 561.0
WH2_k127_8285316_4 Fad dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 546.0
WH2_k127_8285316_5 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 372.0
WH2_k127_8285316_6 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 319.0
WH2_k127_8285316_7 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001818 243.0
WH2_k127_8345435_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 434.0
WH2_k127_8359552_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 2.962e-248 772.0
WH2_k127_8359552_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000003437 235.0
WH2_k127_8370938_0 3'-5' exonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 321.0
WH2_k127_8370938_1 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 311.0
WH2_k127_8370938_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 288.0
WH2_k127_8370938_3 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007619 273.0
WH2_k127_8370938_4 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000001634 225.0
WH2_k127_8370938_5 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000008676 167.0
WH2_k127_8370938_6 - - - - 0.00000000000000000000000000000000000000002643 154.0
WH2_k127_8374280_0 PFAM ABC transporter related K02056 - 3.6.3.17 1.07e-210 664.0
WH2_k127_8374280_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 594.0
WH2_k127_8374280_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 548.0
WH2_k127_8374280_3 PFAM Basic membrane lipoprotein K02058,K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 437.0
WH2_k127_8374280_4 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 443.0
WH2_k127_8381629_0 PFAM AAA ATPase central domain protein K07478 - - 1.869e-230 722.0
WH2_k127_8381629_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000003442 134.0
WH2_k127_8405489_0 peptidase U62, modulator of DNA gyrase K03592 - - 9.084e-243 757.0
WH2_k127_8405489_1 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000004349 98.0
WH2_k127_8405489_2 PIN domain - - - 0.0000000000000000000003502 101.0
WH2_k127_8405489_3 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.00000000000000002451 81.0
WH2_k127_8405489_4 toxin-antitoxin pair type II binding - - - 0.000000000008144 71.0
WH2_k127_850850_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 567.0
WH2_k127_850850_1 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 445.0
WH2_k127_850850_2 Phosphate acetyl butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000003977 149.0
WH2_k127_850850_3 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000002475 120.0
WH2_k127_851588_0 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 461.0
WH2_k127_851588_1 methylglyoxal synthase K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 449.0
WH2_k127_851588_2 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007775 261.0
WH2_k127_851588_3 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000000000000000000000000000000000008462 153.0
WH2_k127_851588_4 Histidine kinase K07649 - 2.7.13.3 0.00000000000000001561 87.0
WH2_k127_8554915_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2134.0
WH2_k127_8560247_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.346e-238 739.0
WH2_k127_8560247_1 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 2.157e-219 686.0
WH2_k127_8560247_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 582.0
WH2_k127_8560247_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 456.0
WH2_k127_8560247_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 439.0
WH2_k127_8560247_5 type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 336.0
WH2_k127_8560247_6 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 312.0
WH2_k127_8560247_7 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000000000000000000000000001832 191.0
WH2_k127_8560247_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000003081 82.0
WH2_k127_8583685_0 Mo-co oxidoreductase dimerisation domain K17225 - - 2.055e-259 803.0
WH2_k127_8583685_1 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 490.0
WH2_k127_8583685_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000001364 109.0
WH2_k127_8583685_11 Sulphur transport - - - 0.0000000000000000000001779 98.0
WH2_k127_8583685_12 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0002643 43.0
WH2_k127_8583685_2 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 437.0
WH2_k127_8583685_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 408.0
WH2_k127_8583685_4 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 332.0
WH2_k127_8583685_5 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 288.0
WH2_k127_8583685_6 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000000000000005426 215.0
WH2_k127_8583685_7 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000000000000000000000000434 194.0
WH2_k127_8583685_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000006349 146.0
WH2_k127_8583685_9 Cytochrome c - - - 0.0000000000000000000000000000000002257 135.0
WH2_k127_8630132_0 PFAM ATP-binding region, ATPase domain protein K10125 - 2.7.13.3 1.418e-237 756.0
WH2_k127_8630132_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K21393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 577.0
WH2_k127_8630132_2 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 465.0
WH2_k127_8630132_3 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 324.0
WH2_k127_8630132_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000001422 218.0
WH2_k127_8630132_5 Tripartite ATP-independent periplasmic transporter dctq component K21394 - - 0.000000000000000000000000000000000000000000000000004046 187.0
WH2_k127_8630754_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 591.0
WH2_k127_8630754_1 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 508.0
WH2_k127_8630754_2 Mannitol dehydrogenase rossman K00007 - 1.1.1.11 0.0000000000000000000000000000000000000000000001165 169.0
WH2_k127_8664906_0 Proton-conducting membrane transporter - - - 1.667e-227 713.0
WH2_k127_8664906_1 Proton-conducting membrane transporter - - - 6.523e-220 691.0
WH2_k127_8664906_2 Na H antiporter, MnhB K05566 - - 0.00000000000000000000000000000000000000000000000000000000000002352 220.0
WH2_k127_8664906_3 Na H antiporter, MnhB K05566 - - 0.0000000000000000000000000000000000000000000000000000000005652 213.0
WH2_k127_8664906_4 COG1006 Multisubunit Na H antiporter, MnhC subunit K05567 - - 0.00000000000000000000000000000000000000005864 154.0
WH2_k127_8664906_5 monovalent cation:proton antiporter activity K05571 - - 0.00000000000000000000000000000000005084 136.0
WH2_k127_8664906_6 Multiple resistance and pH regulation protein F K05570 - - 0.00000000000000000000000000000001198 129.0
WH2_k127_8664906_7 COG1863 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.000000000008041 66.0
WH2_k127_8664906_8 - - - - 0.000004239 55.0
WH2_k127_8712623_0 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 474.0
WH2_k127_8712623_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 315.0
WH2_k127_8712623_2 phosphoribosyltransferase K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000001091 248.0
WH2_k127_8712623_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000000000000000000003734 229.0
WH2_k127_8712623_4 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000001552 171.0
WH2_k127_8714820_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 4.602e-289 893.0
WH2_k127_8714820_1 PFAM 5-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 506.0
WH2_k127_8714820_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 407.0
WH2_k127_8714820_3 PFAM OsmC family protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 284.0
WH2_k127_8714820_4 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007706 260.0
WH2_k127_8714820_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000001719 217.0
WH2_k127_8714820_6 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000001052 121.0
WH2_k127_8714820_7 - - - - 0.0000009454 51.0
WH2_k127_8720980_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1144.0
WH2_k127_8720980_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 614.0
WH2_k127_8720980_2 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000009572 133.0
WH2_k127_8720980_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000131 127.0
WH2_k127_8776324_0 Fe-S oxidoreductase K21834 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 498.0
WH2_k127_8776324_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 298.0
WH2_k127_8776324_2 nitrate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007622 248.0
WH2_k127_8776324_3 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000144 164.0
WH2_k127_8776324_4 Beta-lactamase - - - 0.000000000000000000000000000000556 137.0
WH2_k127_8790382_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 2353.0
WH2_k127_8790382_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1149.0
WH2_k127_8790382_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000000002199 170.0
WH2_k127_8790382_2 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.0 1080.0
WH2_k127_8790382_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 5.173e-284 876.0
WH2_k127_8790382_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.428e-238 745.0
WH2_k127_8790382_5 ABC transporter, transmembrane region K06147 - - 1.168e-211 663.0
WH2_k127_8790382_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 2.396e-206 647.0
WH2_k127_8790382_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 317.0
WH2_k127_8790382_8 Nudix hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 309.0
WH2_k127_8790382_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007101 269.0
WH2_k127_882631_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 511.0
WH2_k127_882631_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 435.0
WH2_k127_882631_2 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 346.0
WH2_k127_882631_3 Predicted integral membrane protein (DUF2282) - - - 0.0000000000000000000000000000000000000000000000001227 179.0
WH2_k127_882631_4 AraC family transcriptional regulator - - - 0.000000000000000000000000000000000009673 137.0
WH2_k127_8893320_0 Extracellular solute-binding protein K02055,K11069 - - 3.346e-215 671.0
WH2_k127_8893320_1 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 322.0
WH2_k127_8893320_2 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000000000000001999 151.0
WH2_k127_8893320_3 DNA topoisomerase, type IA, central domain protein K03169 - 5.99.1.2 0.000000000000000000000000000000001397 130.0
WH2_k127_8893320_4 Protein of unknown function DUF86 - - - 0.000000000000000000000000271 108.0
WH2_k127_8906230_0 AMP-binding enzyme K01897 - 6.2.1.3 4.489e-268 831.0
WH2_k127_8906230_1 acetyl-CoA hydrolase K18288 - - 0.00000000000000000000000000000000000000000000000001657 189.0
WH2_k127_8986789_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 583.0
WH2_k127_8986789_1 General secretory system II, protein E domain protein K02454,K02652,K12276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 396.0
WH2_k127_8986789_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 285.0
WH2_k127_8986789_3 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002229 236.0
WH2_k127_8986789_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000006949 181.0
WH2_k127_8993986_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.345e-280 867.0
WH2_k127_8993986_1 Belongs to the ABC transporter superfamily K17324 - - 9.527e-201 629.0
WH2_k127_8993986_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 466.0
WH2_k127_8993986_3 PFAM regulatory protein DeoR K02444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 455.0
WH2_k127_8993986_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 384.0
WH2_k127_8993986_5 Belongs to the ABC transporter superfamily K17325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 366.0
WH2_k127_8993986_6 Transcriptional regulator K04761 - - 0.0000000000000000974 79.0
WH2_k127_9004957_0 SMART Elongator protein 3 MiaB NifB - - - 2.991e-292 901.0
WH2_k127_9004957_1 histidine kinase HAMP region domain protein K07638 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 548.0
WH2_k127_9004957_2 Two component transcriptional regulator, winged helix family K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 429.0
WH2_k127_9004957_3 Protein of unknown function (DUF541) - - - 0.0000000000000000000000000000000000000000000000000000000002234 210.0
WH2_k127_9004957_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000001383 177.0
WH2_k127_9004957_5 Luciferase family - - - 0.0000000009356 60.0
WH2_k127_9046578_0 PFAM FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 496.0
WH2_k127_9046578_1 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 351.0
WH2_k127_9046578_2 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000000000000000000000000000000000000556 193.0
WH2_k127_9050177_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.243e-243 761.0
WH2_k127_9050177_1 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 479.0
WH2_k127_9050177_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 309.0
WH2_k127_9050177_3 PFAM CreA family protein K05805 - - 0.0000000000000000000000000000000000000000000000000000000000000000001112 234.0
WH2_k127_9050177_4 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000003078 164.0
WH2_k127_9065117_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.803e-278 858.0
WH2_k127_9065117_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 3.044e-198 622.0
WH2_k127_9065117_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 409.0
WH2_k127_9065117_3 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009778 333.0
WH2_k127_9065117_4 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000000000003085 201.0
WH2_k127_9065117_5 Belongs to the ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000000000004363 179.0
WH2_k127_9079215_0 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000007249 200.0
WH2_k127_9079215_1 - - - - 0.000000000000000000000000000000000000000000000000000000009476 204.0
WH2_k127_9079215_2 Cas6 Crispr - - - 0.00000000000000000000000000000000000000000000000001351 186.0
WH2_k127_9079215_3 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000171 160.0
WH2_k127_9079215_4 - - - - 0.00000000000000007291 82.0
WH2_k127_9086293_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 555.0
WH2_k127_9086293_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 457.0
WH2_k127_9086293_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 304.0
WH2_k127_910390_0 Diguanylate cyclase - - - 1.881e-197 653.0
WH2_k127_910390_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 539.0
WH2_k127_910390_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K12368 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 446.0
WH2_k127_910390_3 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 414.0
WH2_k127_910390_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000001695 231.0
WH2_k127_9129952_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 540.0
WH2_k127_9129952_1 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 489.0
WH2_k127_9129952_2 Short-chain dehydrogenase reductase sdr K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000003594 166.0
WH2_k127_9129952_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000009633 109.0
WH2_k127_9138669_0 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 1.227e-246 769.0
WH2_k127_9138669_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 503.0
WH2_k127_9138669_2 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 462.0
WH2_k127_9138669_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 440.0
WH2_k127_9138669_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 405.0
WH2_k127_9138669_5 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 391.0
WH2_k127_9138669_6 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 343.0
WH2_k127_9138669_7 Binding-protein-dependent transport system inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000005761 218.0
WH2_k127_9156431_0 PFAM Type II secretion system protein E K02454,K02652,K12276 - - 2.299e-310 959.0
WH2_k127_9156431_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 6.198e-310 956.0
WH2_k127_9156431_10 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 368.0
WH2_k127_9156431_11 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 353.0
WH2_k127_9156431_12 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 321.0
WH2_k127_9156431_13 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000003257 234.0
WH2_k127_9156431_14 PFAM Lipocalin family protein K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000007241 232.0
WH2_k127_9156431_15 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000000000000000002964 207.0
WH2_k127_9156431_16 Hemerythrin HHE cation binding domain - - - 0.0000000001147 67.0
WH2_k127_9156431_2 Tripartite tricarboxylate transporter TctA family K07793 - - 2.289e-287 887.0
WH2_k127_9156431_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 4.701e-235 733.0
WH2_k127_9156431_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 586.0
WH2_k127_9156431_5 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 484.0
WH2_k127_9156431_6 Permeases of the drug metabolite transporter K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 467.0
WH2_k127_9156431_7 SMART phosphoesterase PHP domain protein K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 457.0
WH2_k127_9156431_8 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 397.0
WH2_k127_9156431_9 PFAM TatD-related deoxyribonuclease K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 389.0
WH2_k127_9187219_0 Involved in the biosynthesis of porphyrin-containing compound - - - 1.54e-198 626.0
WH2_k127_9187219_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001631 253.0
WH2_k127_9187219_2 Domain of unknown function (DUF1850) - - - 0.000000000000000000000000000000000000000000006475 166.0
WH2_k127_9213019_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1048.0
WH2_k127_9213019_1 Involved in the biosynthesis of porphyrin-containing compound - - - 3.953e-197 621.0
WH2_k127_9213019_2 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 519.0
WH2_k127_9213019_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 440.0
WH2_k127_9213019_4 Domain of unknown function (DUF1850) - - - 0.0000000000000000000000000000000000000000000001465 171.0
WH2_k127_9223531_0 AAA domain - - - 0.0 1018.0
WH2_k127_9223531_1 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 474.0
WH2_k127_9223531_2 Crp Fnr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 406.0
WH2_k127_9223531_3 cheY-homologous receiver domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 406.0
WH2_k127_9223531_4 bacterial OsmY and nodulation domain K04065 - - 0.000000000000000000000000000000000000000000000000000000000006949 214.0
WH2_k127_9223531_5 PFAM 17 kDa surface antigen - - - 0.00000000000000000000000000000000000000000008211 164.0
WH2_k127_9223531_6 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000003597 53.0
WH2_k127_9241186_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.307e-281 869.0
WH2_k127_9241186_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 470.0
WH2_k127_9241186_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 460.0
WH2_k127_9333108_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 538.0
WH2_k127_9333108_1 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 479.0
WH2_k127_9333108_2 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 374.0
WH2_k127_9333108_3 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 314.0
WH2_k127_9333108_4 Bacterial regulatory proteins, luxR family K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002412 280.0
WH2_k127_9333108_5 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001645 254.0
WH2_k127_9333108_6 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000000000000000000000000005538 201.0
WH2_k127_9333108_7 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.000000000000000000000000000000000000000000000000001534 183.0
WH2_k127_9333108_8 Domain of unknown function (DUF4148) - - - 0.0000000000000000000000000000000003027 136.0
WH2_k127_9333918_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 484.0
WH2_k127_9333918_1 Cobalamin synthesis protein P47K - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 431.0
WH2_k127_9355128_0 Tripartite tricarboxylate transporter TctA family K07793 - - 2.67e-270 839.0
WH2_k127_9355128_1 PFAM methyltransferase small - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 584.0
WH2_k127_9355128_2 PFAM conserved K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 544.0
WH2_k127_9355128_3 Two component transcriptional regulator, winged helix family K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 303.0
WH2_k127_9355128_4 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000000000000000000000000000000000000000000000000000000000002932 221.0
WH2_k127_9355128_5 Cache domain K11527 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001226 199.0
WH2_k127_9355128_6 Histidine kinase K07649 - 2.7.13.3 0.0000004367 57.0
WH2_k127_9358278_0 PFAM extracellular solute-binding protein family 1 K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 466.0
WH2_k127_9358278_1 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 374.0
WH2_k127_9358278_2 binding-protein-dependent transport systems inner membrane component K05773,K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 342.0
WH2_k127_9358278_3 AzlC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004463 266.0
WH2_k127_9358278_4 Nucleotidyltransferase substrate binding protein like - - - 0.00000000000000000000000000000000000000000000000000000001324 201.0
WH2_k127_9358278_5 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000000000000000000000000000000003788 172.0
WH2_k127_9358278_6 Nucleotidyltransferase domain - - - 0.00000000000000000000000000000004053 128.0
WH2_k127_9364126_0 peptidase U62, modulator of DNA gyrase K03592 - - 1.375e-243 759.0
WH2_k127_9364126_1 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000002443 98.0
WH2_k127_9371352_0 binding-protein-dependent transport systems inner membrane component K02011 - - 0.0 1125.0
WH2_k127_9371352_1 Belongs to the GPI family K01810 - 5.3.1.9 1.727e-296 914.0
WH2_k127_9371352_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 552.0
WH2_k127_9371352_3 Belongs to the ABC transporter superfamily K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 511.0
WH2_k127_9371352_4 extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 281.0
WH2_k127_9371352_5 HaD-superfamily hydrolase, subfamily ia, variant 3 K07025,K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001845 270.0
WH2_k127_9371352_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000001903 213.0
WH2_k127_9371352_7 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000001066 146.0
WH2_k127_9420534_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1105.0
WH2_k127_9420534_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 1.071e-231 724.0
WH2_k127_9420534_2 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 2.561e-228 714.0
WH2_k127_9420534_3 Uncharacterized protein family (UPF0051) K09015 - - 1.068e-218 689.0
WH2_k127_9420534_4 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 481.0
WH2_k127_9420534_5 FeS assembly protein SufB K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 446.0
WH2_k127_9420534_6 Scaffold protein Nfu NifU - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 327.0
WH2_k127_9420534_7 TIGRFAM SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 297.0
WH2_k127_9420534_8 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002319 249.0
WH2_k127_9421432_0 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 1.026e-257 797.0
WH2_k127_9421432_1 PFAM ROK family protein - - - 5.947e-227 707.0
WH2_k127_9421432_2 Belongs to the binding-protein-dependent transport system permease family K10553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 560.0
WH2_k127_9421432_3 PFAM ABC transporter related K10554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 479.0
WH2_k127_9421432_4 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 375.0
WH2_k127_9421432_5 PFAM Periplasmic binding protein LacI transcriptional regulator K10439,K10552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 303.0
WH2_k127_9421432_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000001618 205.0
WH2_k127_9421432_7 Belongs to the RbsD FucU family K02431 - 5.1.3.29 0.0000000000000000000399 96.0
WH2_k127_9449783_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1597.0
WH2_k127_9449783_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 426.0
WH2_k127_9449783_2 phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 357.0
WH2_k127_9449783_3 PFAM phosphate transporter K03306 - - 0.000000000000000000000000006803 111.0
WH2_k127_9452499_0 Belongs to the GARS family K01945 - 6.3.4.13 3.414e-235 732.0
WH2_k127_9452499_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 545.0
WH2_k127_9452499_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000002165 223.0
WH2_k127_9458450_0 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 567.0
WH2_k127_9458450_1 PFAM Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 443.0
WH2_k127_9458450_2 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 374.0
WH2_k127_9458450_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 312.0
WH2_k127_9458450_4 PFAM Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000004212 220.0
WH2_k127_9458450_5 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000001816 211.0
WH2_k127_9476326_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K13482 - 1.17.1.4 2.49e-217 683.0
WH2_k127_9476326_1 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 283.0
WH2_k127_9476326_2 regulatory protein Crp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002293 267.0
WH2_k127_9534593_0 PFAM glucose-methanol-choline oxidoreductase K00108 - 1.1.99.1 2.162e-200 629.0
WH2_k127_9534593_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 502.0
WH2_k127_9534593_2 PFAM ABC transporter related K02065 - - 0.0000000000000000000000000000000000002101 156.0
WH2_k127_9541184_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 4.412e-194 611.0
WH2_k127_9541184_1 PFAM peptidase M61 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 610.0
WH2_k127_9541184_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 491.0
WH2_k127_9541184_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 367.0
WH2_k127_9541184_4 Glycosyl hydrolase family 30 beta sandwich domain K01201 - 3.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 338.0
WH2_k127_9542317_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 1.357e-199 625.0
WH2_k127_9542317_1 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 314.0
WH2_k127_9542317_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001014 269.0
WH2_k127_9542317_3 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000000000000000000000004024 179.0
WH2_k127_9626749_0 Nucleotidyl transferase K00966 - 2.7.7.13 1.558e-210 657.0
WH2_k127_9626749_1 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 579.0
WH2_k127_9626749_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 362.0
WH2_k127_9626749_3 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000001134 188.0
WH2_k127_9628169_0 type I secretion outer membrane protein, TolC family K12543 - - 6.04e-293 910.0
WH2_k127_9628169_1 LapD/MoxY periplasmic domain - - - 4.204e-289 899.0
WH2_k127_9628169_2 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 325.0
WH2_k127_9628169_3 TPM domain - - - 0.00000000000000000000000000000000000000000000000000000000004098 209.0
WH2_k127_9628169_4 lytic transglycosylase - - - 0.0000007176 53.0
WH2_k127_9694392_0 Diguanylate cyclase with PAS PAC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 605.0
WH2_k127_9694392_1 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 307.0
WH2_k127_9694392_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000002348 102.0
WH2_k127_9733166_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0 2298.0
WH2_k127_9733166_1 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 4.545e-290 891.0
WH2_k127_9733166_2 Major facilitator superfamily - - - 6.648e-210 657.0
WH2_k127_9733166_3 Radical SAM superfamily K04069 - 1.97.1.4 2.57e-205 642.0
WH2_k127_9733166_4 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 391.0
WH2_k127_9733166_5 PFAM AMMECR1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005643 231.0
WH2_k127_9733166_6 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000003867 63.0
WH2_k127_9736399_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.626e-203 638.0
WH2_k127_9736399_1 Evidence 4 Homologs of previously reported genes of - - - 5.097e-198 629.0
WH2_k127_9736399_2 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 526.0
WH2_k127_9736454_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 488.0
WH2_k127_9736454_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 444.0
WH2_k127_9736454_2 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 329.0
WH2_k127_9736454_3 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000000000000000003159 228.0
WH2_k127_9748813_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1139.0
WH2_k127_9748813_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 1.699e-200 627.0
WH2_k127_9748813_2 Transcriptional regulator, GntR family K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 421.0
WH2_k127_9748813_3 PFAM succinate dehydrogenase cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001011 252.0
WH2_k127_9748813_4 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000005951 223.0
WH2_k127_9748813_5 TIGRFAM Succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.0000000000000000000000000000000000000000000000000000000000001577 217.0
WH2_k127_9748813_6 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000013 92.0
WH2_k127_9776128_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 2.691e-238 742.0
WH2_k127_9776128_1 Exonuclease, RNase T and DNA polymerase III K01141 - 3.1.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 511.0
WH2_k127_9776128_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 406.0
WH2_k127_9776128_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004409 251.0
WH2_k127_9776128_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000004103 162.0
WH2_k127_9776128_5 - - - - 0.0000000000000000000000000000000000000001954 157.0
WH2_k127_9779149_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 6.026e-239 742.0
WH2_k127_9779149_1 PFAM acyl-CoA dehydrogenase domain protein - - - 6.466e-221 691.0
WH2_k127_9779149_2 Belongs to the thiolase family K00626 - 2.3.1.9 2.178e-211 661.0
WH2_k127_9779149_3 PFAM TrkA-N domain protein K03499 - - 7.579e-211 663.0
WH2_k127_9779149_4 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 580.0
WH2_k127_9779149_5 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 571.0
WH2_k127_9779149_6 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 487.0
WH2_k127_9819931_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 5e-324 1007.0
WH2_k127_9819931_1 ammonium transporter K03320,K06580 - - 2.098e-239 742.0
WH2_k127_9819931_10 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 309.0
WH2_k127_9819931_11 Redoxin K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 287.0
WH2_k127_9819931_12 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 287.0
WH2_k127_9819931_13 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 286.0
WH2_k127_9819931_14 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000000000000000000000004522 222.0
WH2_k127_9819931_15 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.000000000000000000000000000000000000000004625 156.0
WH2_k127_9819931_16 LTXXQ motif family protein - - - 0.00000000000000000000000000000000000002146 152.0
WH2_k127_9819931_17 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000000001856 117.0
WH2_k127_9819931_18 Protein of unknown function (DUF2788) - - - 0.000000000000000000000000001317 123.0
WH2_k127_9819931_19 Heavy metal transport detoxification protein K07213 - - 0.00000000000000000006252 91.0
WH2_k127_9819931_2 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 6.239e-237 737.0
WH2_k127_9819931_3 HD domain - - - 7.6e-206 662.0
WH2_k127_9819931_4 Belongs to the ParA family K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 511.0
WH2_k127_9819931_5 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009467 481.0
WH2_k127_9819931_6 May be involved in recombination K03554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 447.0
WH2_k127_9819931_7 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 341.0
WH2_k127_9819931_8 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 336.0
WH2_k127_9819931_9 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 327.0
WH2_k127_9825832_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 4.629e-243 758.0
WH2_k127_9825832_1 Histidinol dehydrogenase - - - 7.082e-226 705.0
WH2_k127_9825832_10 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000008266 86.0
WH2_k127_9825832_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 7.383e-221 690.0
WH2_k127_9825832_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 601.0
WH2_k127_9825832_4 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 580.0
WH2_k127_9825832_5 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 413.0
WH2_k127_9825832_6 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 410.0
WH2_k127_9825832_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 390.0
WH2_k127_9825832_8 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 385.0
WH2_k127_9825832_9 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000000000001621 136.0
WH2_k127_984087_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1294.0
WH2_k127_984087_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 577.0
WH2_k127_984087_10 Asp/Glu/Hydantoin racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 385.0
WH2_k127_984087_11 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 375.0
WH2_k127_984087_12 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 367.0
WH2_k127_984087_13 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 339.0
WH2_k127_984087_14 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008912 261.0
WH2_k127_984087_15 Asp Glu Hydantoin racemase K01799 - 5.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000006733 230.0
WH2_k127_984087_16 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000026 216.0
WH2_k127_984087_17 FCD - - - 0.000000000000000000000000000000000000000000000000000000002891 207.0
WH2_k127_984087_18 Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000003899 201.0
WH2_k127_984087_19 PFAM amidohydrolase K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000009498 192.0
WH2_k127_984087_2 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 555.0
WH2_k127_984087_20 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000007776 172.0
WH2_k127_984087_21 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000179 179.0
WH2_k127_984087_22 HIUase/Transthyretin family K07127 - 3.5.2.17 0.000000000000000000000000000000000000003251 149.0
WH2_k127_984087_23 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000009284 139.0
WH2_k127_984087_24 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000008616 54.0
WH2_k127_984087_3 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 558.0
WH2_k127_984087_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 501.0
WH2_k127_984087_5 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 461.0
WH2_k127_984087_6 PFAM ABC transporter K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 435.0
WH2_k127_984087_7 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 408.0
WH2_k127_984087_8 Hydantoin racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 392.0
WH2_k127_984087_9 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 395.0
WH2_k127_9846751_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 402.0
WH2_k127_9846751_1 PFAM periplasmic binding protein K02016,K06858 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 387.0
WH2_k127_9846751_2 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 376.0
WH2_k127_9846751_3 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000002603 261.0
WH2_k127_9853277_0 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 463.0
WH2_k127_9853277_1 TIGRFAM phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 411.0
WH2_k127_9853277_2 histidine kinase A domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 399.0
WH2_k127_9853277_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 387.0
WH2_k127_9853277_4 histidine kinase A domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000001245 151.0
WH2_k127_9853277_5 - - - - 0.0000000000000000002793 90.0
WH2_k127_9856016_0 TIGRFAM arsenite-activated ATPase ArsA K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 478.0
WH2_k127_9856016_1 permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 359.0
WH2_k127_9856016_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 339.0
WH2_k127_9856016_3 SMART regulatory protein, ArsR K03892 - - 0.0000000000000000000000000000000000000000000000000000000001531 203.0
WH2_k127_9856016_4 Arsenical resistance operon trans-acting repressor ArsD - - - 0.0000000000000000000000000000000000000000000000000000001465 196.0
WH2_k127_9857172_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 585.0
WH2_k127_9857172_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 537.0
WH2_k127_9857172_2 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 401.0
WH2_k127_9857172_3 Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 366.0
WH2_k127_9857172_4 Peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000007301 230.0
WH2_k127_9857172_5 - - - - 0.00008235 46.0
WH2_k127_9859024_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00480,K20940,K22270 - 1.14.13.1,1.14.13.218,1.14.13.24 6.087e-224 707.0
WH2_k127_9859024_1 PFAM Cupin 2, conserved barrel domain protein K00450 - 1.13.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 579.0
WH2_k127_9859024_2 PFAM fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 427.0
WH2_k127_9859024_3 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001257 256.0
WH2_k127_9859024_4 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000000001356 186.0
WH2_k127_9859024_5 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000312 125.0
WH2_k127_9859024_6 Alpha beta hydrolase K01561 - 3.8.1.3 0.000000000000000000000000003124 112.0
WH2_k127_9863758_0 PFAM oxidoreductase domain protein K00010,K18067 - 1.1.1.18,1.1.1.369,1.3.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 537.0
WH2_k127_9863758_1 ABC transporter K06020 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 524.0
WH2_k127_9863758_2 Protein of unknown function (DUF1631) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 535.0
WH2_k127_9863758_3 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 426.0
WH2_k127_9863758_4 MOSC domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002891 273.0
WH2_k127_9863758_5 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004798 259.0
WH2_k127_9863758_6 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000000000001936 223.0
WH2_k127_9863758_7 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000000001072 134.0
WH2_k127_9863758_8 PFAM peptidase S16 lon domain protein K07157 - - 0.000002998 49.0
WH2_k127_9879846_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0 1282.0
WH2_k127_9879846_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 9.958e-215 674.0
WH2_k127_9879846_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 567.0
WH2_k127_9879846_3 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 562.0
WH2_k127_9879846_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 291.0
WH2_k127_9879846_5 PFAM Fimbrial assembly family protein K02663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000225 279.0
WH2_k127_9879846_6 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006112 274.0
WH2_k127_9879846_7 Belongs to the frataxin family K06202 - - 0.00000000000000000000000000000000000000000000000001781 181.0
WH2_k127_9879846_8 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000009551 126.0
WH2_k127_9879846_9 Prokaryotic lipoprotein-attachment site - - - 0.0000007989 58.0
WH2_k127_9881489_0 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 374.0
WH2_k127_9881489_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 342.0
WH2_k127_9881489_2 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000000000000000008566 149.0
WH2_k127_9881489_3 ATP synthase K02116 - - 0.0000000000000000000000000000000000154 140.0
WH2_k127_9891588_0 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 341.0
WH2_k127_9891588_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 302.0
WH2_k127_9891588_2 Histidine kinase - - - 0.00000000000000001888 96.0
WH2_k127_9898718_0 Periplasmic binding protein K01999 - - 5.457e-220 685.0
WH2_k127_9898718_1 AMP-binding enzyme K01912 - 6.2.1.30 9.206e-202 632.0
WH2_k127_9898718_2 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 512.0
WH2_k127_9911533_0 PFAM oxidoreductase domain protein K00010,K18067 - 1.1.1.18,1.1.1.369,1.3.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 485.0
WH2_k127_9911533_1 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 368.0
WH2_k127_9911533_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 344.0
WH2_k127_9911533_3 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000002786 246.0
WH2_k127_9936065_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 489.0
WH2_k127_9936065_1 Protein of unknown function (DUF455) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 301.0
WH2_k127_9936065_2 transferase hexapeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 281.0
WH2_k127_9939630_0 PFAM Lytic transglycosylase catalytic K08309 - - 5.129e-276 863.0
WH2_k127_9939630_1 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000006123 147.0
WH2_k127_9957230_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 411.0
WH2_k127_9957230_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 416.0
WH2_k127_9957230_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 333.0
WH2_k127_9957230_3 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 313.0
WH2_k127_9957230_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 295.0
WH2_k127_9957230_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000000000004418 224.0
WH2_k127_9957230_6 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000000000000004788 156.0
WH2_k127_9983717_0 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 2.176e-246 764.0
WH2_k127_9983717_1 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 366.0
WH2_k127_9983717_2 Bacterial extracellular solute-binding protein, family 7 K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 286.0
WH2_k127_9986039_0 GTP-binding protein TypA K06207 - - 0.0 1182.0
WH2_k127_9986039_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 597.0
WH2_k127_9986039_2 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 508.0
WH2_k127_9986039_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 474.0
WH2_k127_9986039_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 454.0
WH2_k127_9986039_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 447.0
WH2_k127_9986039_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000000000000000000000000473 229.0