Overview

ID MAG04130
Name WH2_bin.9
Sample SMP0107
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Xanthomonadales
Family Xanthomonadaceae
Genus Arenimonas
Species
Assembly information
Completeness (%) 75.37
Contamination (%) 2.18
GC content (%) 52.0
N50 (bp) 4,428
Genome size (bp) 1,322,611

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1508

Gene name Description KEGG GOs EC E-value Score Sequence
WH2_k127_10080406_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 316.0
WH2_k127_10080406_1 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003488 279.0
WH2_k127_10080406_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003175 265.0
WH2_k127_10080406_3 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000002294 174.0
WH2_k127_10080406_4 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000002169 132.0
WH2_k127_10088012_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 531.0
WH2_k127_10088012_1 Exodeoxyribonuclease IX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 402.0
WH2_k127_10088012_2 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 372.0
WH2_k127_10088012_3 endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 316.0
WH2_k127_10088012_4 DNA mismatch repair protein MutT K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002914 270.0
WH2_k127_10088012_5 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000001615 202.0
WH2_k127_10088012_6 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000003845 183.0
WH2_k127_10101889_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 2.055e-210 665.0
WH2_k127_10101889_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 592.0
WH2_k127_10101889_2 PFAM Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 339.0
WH2_k127_10101889_3 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000000002701 131.0
WH2_k127_10101889_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000001573 67.0
WH2_k127_10131396_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 516.0
WH2_k127_10131396_1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 389.0
WH2_k127_10131396_2 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000007349 106.0
WH2_k127_10131396_3 - - - - 0.00000000001778 72.0
WH2_k127_10138220_0 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 351.0
WH2_k127_10138220_1 lysine 2,3-aminomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 317.0
WH2_k127_10138220_2 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000002601 216.0
WH2_k127_10187209_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 476.0
WH2_k127_10187209_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 461.0
WH2_k127_10187209_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 456.0
WH2_k127_10187209_3 phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 439.0
WH2_k127_10187209_4 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 409.0
WH2_k127_10187209_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 315.0
WH2_k127_10187209_6 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 299.0
WH2_k127_10187209_7 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000009854 158.0
WH2_k127_10187209_8 - - - - 0.0000000000000000003183 90.0
WH2_k127_10211867_0 cyclomaltodextrin glucanotransferase K00701 - 2.4.1.19 5.673e-234 737.0
WH2_k127_10211867_1 LacI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 458.0
WH2_k127_10211867_2 Major facilitator superfamily K16211 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 313.0
WH2_k127_10228679_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1264.0
WH2_k127_10228679_1 Participates in both transcription termination and antitermination K02600 - - 6.299e-261 811.0
WH2_k127_10228679_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000005319 226.0
WH2_k127_10228679_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000000000005634 191.0
WH2_k127_10260170_0 Helicase K03579 - 3.6.4.13 0.0 1101.0
WH2_k127_10260170_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 550.0
WH2_k127_10260170_2 NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 535.0
WH2_k127_10260170_3 Preprotein translocase subunit TatD K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 419.0
WH2_k127_10260170_4 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 326.0
WH2_k127_10260170_5 Belongs to the pseudouridine synthase RsuA family K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 293.0
WH2_k127_10260170_6 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006991 242.0
WH2_k127_10260170_7 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000001022 186.0
WH2_k127_10260170_8 Protein chain release factor B K15034 - - 0.0000000000000000000000000000000000002758 146.0
WH2_k127_102737_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 605.0
WH2_k127_102737_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 517.0
WH2_k127_102737_2 Protein of unknown function (DUF1415) K09941 - - 0.00000000000000000000000000000000000000000000000000001228 197.0
WH2_k127_102737_3 Protein of unknown function (DUF1304) K08987 - - 0.0000000000000000000000000000000000000000001583 161.0
WH2_k127_102737_4 - - - - 0.00000000001504 66.0
WH2_k127_102737_5 Cache domain - - - 0.000001101 58.0
WH2_k127_10288665_0 electron transfer flavoprotein beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 432.0
WH2_k127_10288665_1 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 353.0
WH2_k127_10288665_2 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 352.0
WH2_k127_10288665_3 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.000000000000000000000000000000001486 128.0
WH2_k127_10335011_0 S1 P1 nuclease - - - 0.00000000000000206 79.0
WH2_k127_10335011_1 Aspartyl protease K06985 - - 0.00000000006782 74.0
WH2_k127_10335011_2 lysine biosynthetic process via aminoadipic acid - - - 0.00001774 47.0
WH2_k127_10354956_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 582.0
WH2_k127_10354956_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000002171 209.0
WH2_k127_10354956_2 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000002458 149.0
WH2_k127_10354956_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000427 89.0
WH2_k127_10354956_4 protein conserved in bacteria K09938 - - 0.00000001467 61.0
WH2_k127_10365099_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 569.0
WH2_k127_10365099_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 348.0
WH2_k127_10365099_2 transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 307.0
WH2_k127_10365099_3 cytochrome K00413 - - 0.0000000000000000000000344 102.0
WH2_k127_10365099_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0003696 50.0
WH2_k127_10399506_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 576.0
WH2_k127_10399506_1 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 309.0
WH2_k127_10399506_2 Cysteine dioxygenase type I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001105 279.0
WH2_k127_10399506_3 - - - - 0.00000000000000000000000000000000000000000000002111 175.0
WH2_k127_10457255_0 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 505.0
WH2_k127_10457255_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001922 267.0
WH2_k127_10457255_2 4TM region of pyridine nucleotide transhydrogenase, mitoch - - - 0.0000000000000000000000000000000000000000000000001451 177.0
WH2_k127_10457255_3 Protein of unknown function (DUF1631) - - - 0.000000000000000000000133 98.0
WH2_k127_10502763_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 374.0
WH2_k127_10502763_1 peptidoglycan-binding protein, lysm - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 304.0
WH2_k127_10502763_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000003912 261.0
WH2_k127_10502763_3 DNA processing protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000007125 236.0
WH2_k127_10538821_0 carboxylase K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 614.0
WH2_k127_10538821_1 enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000356 113.0
WH2_k127_10620910_0 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 382.0
WH2_k127_10620910_1 protein conserved in bacteria K09938 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 287.0
WH2_k127_10620910_2 Belongs to the DnaA family. HdA subfamily K10763 - - 0.0000000000000000000000000000000000000000000000000000000000002728 219.0
WH2_k127_10651013_0 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 436.0
WH2_k127_10651013_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 387.0
WH2_k127_10651013_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 379.0
WH2_k127_10651013_3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000006068 129.0
WH2_k127_10699967_0 Acetyltransferase (GNAT) domain - - - 1.446e-199 637.0
WH2_k127_10699967_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 420.0
WH2_k127_10699967_2 PFAM metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000006765 207.0
WH2_k127_10699967_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000141 108.0
WH2_k127_10708975_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 9.093e-205 641.0
WH2_k127_10708975_1 NAD FAD-binding protein K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 513.0
WH2_k127_10708975_2 synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 453.0
WH2_k127_10708975_3 fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 389.0
WH2_k127_10708975_4 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002784 280.0
WH2_k127_10708975_5 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000001539 270.0
WH2_k127_10708975_6 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000001015 155.0
WH2_k127_10731742_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.33e-230 721.0
WH2_k127_10731742_1 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 546.0
WH2_k127_10731742_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000001679 239.0
WH2_k127_1148791_0 Male sterility protein - - - 0.0 1084.0
WH2_k127_1148791_1 Bacterial transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 310.0
WH2_k127_1148791_2 Belongs to the agmatine deiminase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001245 283.0
WH2_k127_1148791_3 Poly(hydroxyalcanoate) granule associated protein - - - 0.0000000000000000000000000000000000000000000000005045 181.0
WH2_k127_1148791_4 Acyl CoA binding protein - - - 0.00000000000000000000000000000001022 128.0
WH2_k127_1148791_5 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000000001303 82.0
WH2_k127_1148791_6 Protein of unknown function, DUF481 - - - 0.0000006168 54.0
WH2_k127_1188579_0 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 450.0
WH2_k127_1188579_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 378.0
WH2_k127_1188579_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 331.0
WH2_k127_1188579_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 325.0
WH2_k127_1188579_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001463 241.0
WH2_k127_1188579_5 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000001815 164.0
WH2_k127_1188579_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000001079 152.0
WH2_k127_1188579_7 ACR protein K07040 - - 0.000000000000000000000003115 104.0
WH2_k127_1188579_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0004742 44.0
WH2_k127_1199687_0 MTH538 TIR-like domain (DUF1863) K12132 - 2.7.11.1 2.786e-203 653.0
WH2_k127_1199687_1 Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 544.0
WH2_k127_1220301_0 Belongs to the glutamate synthase family - - - 3.449e-225 710.0
WH2_k127_1220301_1 oxidoreductase K09471 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 545.0
WH2_k127_1220301_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 375.0
WH2_k127_1220301_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 336.0
WH2_k127_1220301_4 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000000000000000000000000000000000000008254 226.0
WH2_k127_1220301_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000808 162.0
WH2_k127_1220301_6 oxidoreductase K09471 - - 0.000000001356 59.0
WH2_k127_1220301_7 - - - - 0.00000001359 61.0
WH2_k127_1267572_0 Efflux pump membrane transporter K19585 - - 2.855e-256 799.0
WH2_k127_1267572_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298,K19586 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 427.0
WH2_k127_1267572_2 Bacterial PH domain K08981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004541 251.0
WH2_k127_1267572_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000008028 154.0
WH2_k127_1268826_0 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 3.932e-261 808.0
WH2_k127_1268826_1 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001195 229.0
WH2_k127_1268826_2 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000003383 204.0
WH2_k127_1268826_3 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000001139 150.0
WH2_k127_1268826_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000342 143.0
WH2_k127_1268826_5 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000003799 61.0
WH2_k127_1281058_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 1.386e-311 967.0
WH2_k127_1281058_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003617 254.0
WH2_k127_1293048_0 CMP-binding protein K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 330.0
WH2_k127_1293048_1 Cardiolipin synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 270.0
WH2_k127_1293048_2 phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007374 236.0
WH2_k127_1336157_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.434e-254 802.0
WH2_k127_1336157_1 receptor K16090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 341.0
WH2_k127_1463743_0 In Escherichia coli this enzyme appears to be an NAD NADP -dependent succinate semialdehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 3.977e-207 653.0
WH2_k127_1463743_1 Spermidine putrescine ABC transporter permease K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 419.0
WH2_k127_1463743_2 ABC-type spermidine putrescine transport system, permease component I K11075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 320.0
WH2_k127_1463743_3 PFAM Transglycosylase-associated protein - - - 0.000000000000000000002643 96.0
WH2_k127_1506996_0 glutamate--cysteine ligase K01919 - 6.3.2.2 1.059e-244 761.0
WH2_k127_1506996_1 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 321.0
WH2_k127_1506996_2 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005169 266.0
WH2_k127_1506996_3 Methyltransferase type 12 - - - 0.000000000000000000000000000008112 123.0
WH2_k127_1506996_4 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000004045 114.0
WH2_k127_1509855_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 419.0
WH2_k127_1509855_1 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002982 278.0
WH2_k127_1509855_2 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009826 271.0
WH2_k127_1509855_3 protein conserved in bacteria - - - 0.0000000000000000002154 88.0
WH2_k127_1509855_4 ABC-type uncharacterized transport system - - - 0.000001689 53.0
WH2_k127_1547388_0 RNA polymerase sigma factor RpoH K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 470.0
WH2_k127_1547388_1 helix_turn_helix, Lux Regulon K20264 - - 0.00000000000000000000000000000000000000000000002993 177.0
WH2_k127_1547388_2 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000006689 160.0
WH2_k127_1547388_3 Signal transduction histidine kinase, glucose-6-phosphate specific K07675,K20263 - 2.7.13.3 0.00000000000000000000000008467 119.0
WH2_k127_1558239_0 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 527.0
WH2_k127_1558239_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 323.0
WH2_k127_1558239_2 Protein of unknown function (DUF2884) - - - 0.000000000000000000000000000000000000000000000002062 182.0
WH2_k127_1558239_3 dehydrogenase K00382 - 1.8.1.4 0.000000000000000000007077 95.0
WH2_k127_1661417_0 peptidase K07386 - - 8.673e-283 884.0
WH2_k127_1661417_1 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 - - 0.0000000000000000007532 89.0
WH2_k127_1661417_2 Tetratricopeptide repeat - - - 0.0000000003368 71.0
WH2_k127_1677854_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1334.0
WH2_k127_1677854_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000003721 87.0
WH2_k127_1687427_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 401.0
WH2_k127_1687427_1 (Lipo)protein K07121 - - 0.000000000000000000000000000000000000000000000000000000000102 221.0
WH2_k127_1687427_2 - - - - 0.0000001406 57.0
WH2_k127_1688506_0 ABC transporter, ATP-binding protein K18893 - - 1.487e-215 677.0
WH2_k127_1688506_1 Methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 542.0
WH2_k127_1688506_2 Belongs to the arginase family K01479,K01480 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0030145,GO:0034641,GO:0042401,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 486.0
WH2_k127_1700490_0 Histidine kinase K07641 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 502.0
WH2_k127_1700490_1 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 447.0
WH2_k127_1700490_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 370.0
WH2_k127_1700490_3 Response regulator in two-component regulatory system with CreC K07663 - - 0.0000000007151 59.0
WH2_k127_1743970_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 2.046e-234 729.0
WH2_k127_1743970_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 470.0
WH2_k127_1743970_2 Belongs to the phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 337.0
WH2_k127_1743970_3 protein conserved in bacteria - - - 0.000000000000003097 85.0
WH2_k127_177592_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 1.394e-260 812.0
WH2_k127_177592_1 twitching motility protein K02670 - - 1.115e-219 684.0
WH2_k127_177592_2 twitching motility protein K02669 - - 2.758e-197 619.0
WH2_k127_177592_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 332.0
WH2_k127_177592_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000001834 225.0
WH2_k127_177592_5 ABC transporter substrate-binding protein K02016 - - 0.00000000000000000000000000000000001544 136.0
WH2_k127_1776478_0 Prolyl oligopeptidase K01322 - 3.4.21.26 0.0 1083.0
WH2_k127_1776478_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 477.0
WH2_k127_1776478_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 441.0
WH2_k127_1776478_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 293.0
WH2_k127_1776478_4 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000005119 233.0
WH2_k127_1776478_5 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 0.00000000000000000001582 93.0
WH2_k127_1829093_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.598e-205 644.0
WH2_k127_1829093_1 transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002134 246.0
WH2_k127_1829093_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0003189 45.0
WH2_k127_1831392_0 gtp-binding protein K06207 - - 0.0 1129.0
WH2_k127_1831392_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 5.555e-195 612.0
WH2_k127_1831392_10 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000000000001302 189.0
WH2_k127_1831392_11 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000008941 130.0
WH2_k127_1831392_12 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.000000000000000000000000000001796 121.0
WH2_k127_1831392_13 Thioredoxin-like - - - 0.0000000000000000000004285 102.0
WH2_k127_1831392_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 538.0
WH2_k127_1831392_3 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 392.0
WH2_k127_1831392_4 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 366.0
WH2_k127_1831392_5 aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 311.0
WH2_k127_1831392_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008255 282.0
WH2_k127_1831392_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000009321 261.0
WH2_k127_1831392_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000202 211.0
WH2_k127_1831392_9 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001275 189.0
WH2_k127_1864479_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.193e-216 681.0
WH2_k127_1864479_1 transcriptional regulator K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 308.0
WH2_k127_1864479_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000004725 98.0
WH2_k127_1866233_0 dna polymerase K02337 - 2.7.7.7 4.348e-303 939.0
WH2_k127_1943290_0 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 509.0
WH2_k127_1943290_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 398.0
WH2_k127_1943290_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 365.0
WH2_k127_1943290_3 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000004044 199.0
WH2_k127_1943290_4 PQ loop repeat K15383 - - 0.00000000000000000000000000004711 117.0
WH2_k127_1943290_5 endonuclease - - - 0.00000000000000000001472 93.0
WH2_k127_1976842_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.302e-309 963.0
WH2_k127_1976842_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001039 272.0
WH2_k127_197934_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1120.0
WH2_k127_197934_1 Succinate dehydrogenase K00241 - - 0.0000000000000000000000000000000000000000000467 164.0
WH2_k127_197934_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000008044 154.0
WH2_k127_197934_3 succinate dehydrogenase K00242 - - 0.00000000000000000000000000000000003216 139.0
WH2_k127_197934_4 Protein of unknown function (DUF1674) - - - 0.000000000005658 66.0
WH2_k127_2017065_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 386.0
WH2_k127_2017065_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 288.0
WH2_k127_2017065_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001835 270.0
WH2_k127_2017065_3 membrane K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006545 265.0
WH2_k127_2017065_4 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000002331 241.0
WH2_k127_2035107_0 Family 3 K05349 - 3.2.1.21 1.923e-232 737.0
WH2_k127_2035107_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 534.0
WH2_k127_2071477_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 3.082e-238 742.0
WH2_k127_2071477_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003792 251.0
WH2_k127_2109346_0 protein conserved in bacteria K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 531.0
WH2_k127_2109346_1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease K03694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004118 245.0
WH2_k127_2109346_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000001143 251.0
WH2_k127_2109346_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000006821 145.0
WH2_k127_2120800_0 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 410.0
WH2_k127_2120800_1 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 324.0
WH2_k127_2120800_2 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000004867 170.0
WH2_k127_215986_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.829e-301 926.0
WH2_k127_215986_1 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000005907 209.0
WH2_k127_215986_2 heparin binding - - - 0.000000003952 63.0
WH2_k127_2194699_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0 1800.0
WH2_k127_2194699_1 Tyrosine recombinase xerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 361.0
WH2_k127_2194699_2 overlaps another CDS with the same product name K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 289.0
WH2_k127_2194699_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001049 263.0
WH2_k127_2194699_4 protein conserved in bacteria K09983 - - 0.000000000000000000000000000000000000000000001214 170.0
WH2_k127_2194699_5 RDD family - - - 0.00000000000000000000000000000000006566 138.0
WH2_k127_2194699_6 Excalibur calcium-binding domain - - - 0.0000000000000000000000000000000004242 134.0
WH2_k127_2194699_7 xyloglucan:xyloglucosyl transferase activity - - - 0.000000000000000000162 93.0
WH2_k127_2209591_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 480.0
WH2_k127_2209591_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 296.0
WH2_k127_2305933_0 Phosphate starvation protein PhoH K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 553.0
WH2_k127_2305933_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 403.0
WH2_k127_2305933_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 392.0
WH2_k127_2305933_3 Glycine cleavage system regulatory protein K03567 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 289.0
WH2_k127_2305933_4 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000000000005142 213.0
WH2_k127_2305933_5 Gram-negative-bacterium-type cell outer membrane assembly - - - 0.0000001445 61.0
WH2_k127_2308689_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1030.0
WH2_k127_2308689_1 Penicillin acylase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 457.0
WH2_k127_2324781_0 Belongs to the Orn Lys Arg decarboxylase class-II family K12526 - 2.7.2.4,4.1.1.20 0.0 1142.0
WH2_k127_2324781_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 308.0
WH2_k127_2324781_2 - - - - 0.000000000000000000000000000000000000000234 155.0
WH2_k127_2324781_3 protein, YerC YecD - - - 0.0000000000000000000000000003091 117.0
WH2_k127_2324781_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000001965 71.0
WH2_k127_2344020_0 COG1228 Imidazolonepropionase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 493.0
WH2_k127_2344020_1 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000000000000000000000000000004661 196.0
WH2_k127_2344020_2 desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000001592 193.0
WH2_k127_2344020_3 Tetratricopeptide repeat - - - 0.000000000000000000000000003545 114.0
WH2_k127_2359847_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 2.865e-196 617.0
WH2_k127_2359847_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000003725 160.0
WH2_k127_2359847_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000007505 138.0
WH2_k127_2387250_0 peptidase - - - 2.013e-311 959.0
WH2_k127_2387250_1 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 477.0
WH2_k127_2387250_2 metallo-beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 443.0
WH2_k127_2387250_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000008509 237.0
WH2_k127_2387250_4 MAPEG family - - - 0.000000000000000000000000000000000000000000002794 169.0
WH2_k127_2387250_5 - - - - 0.00000000000000000000000000000000000000000001516 168.0
WH2_k127_2387250_6 ferredoxin - - - 0.000000000000000000000000000000000000000002448 155.0
WH2_k127_2387250_7 MAPEG family - - - 0.000000000000000000000000000000000000001862 151.0
WH2_k127_2401433_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 437.0
WH2_k127_2401433_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000001139 193.0
WH2_k127_2401433_2 Cro/C1-type HTH DNA-binding domain K07729 - - 0.0000000000000000000213 92.0
WH2_k127_2416726_0 abc transporter, permease K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 366.0
WH2_k127_2416726_1 abc transporter atp-binding protein K02065 - - 0.000000000000000000000000000000000000000000001743 167.0
WH2_k127_2416726_2 Threonine/Serine exporter, ThrE - - - 0.0000000000000000000000294 104.0
WH2_k127_2424613_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 1.044e-209 656.0
WH2_k127_2424613_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 398.0
WH2_k127_2424613_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000001462 171.0
WH2_k127_2424613_3 Preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000000000000000001648 147.0
WH2_k127_2432694_0 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 518.0
WH2_k127_2432694_1 Tetratricopeptide repeat - - - 0.000001322 60.0
WH2_k127_2432694_2 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.0008481 45.0
WH2_k127_2434312_0 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000003295 261.0
WH2_k127_2434312_1 DNA mismatch repair protein MutT - - - 0.00000000000000000000000000000000000000000000000000001063 196.0
WH2_k127_2434312_2 Peptidyl-prolyl cis-trans K01802,K03773 - 5.2.1.8 0.00000000000000001043 85.0
WH2_k127_2434312_3 Protein of unknown function (DUF1289) - - - 0.0000000000004266 70.0
WH2_k127_2457263_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 376.0
WH2_k127_2457263_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000675 260.0
WH2_k127_2457263_2 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000002526 231.0
WH2_k127_2457263_3 Oligoketide cyclase - - - 0.000000000000000000000000000000000000000000000000003489 187.0
WH2_k127_2457263_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000000000000000001066 168.0
WH2_k127_2457263_5 response to cobalt ion - - - 0.000000000000000000000003004 108.0
WH2_k127_2457263_6 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000003396 74.0
WH2_k127_24607_0 UDP-N-acetylglucosamine 2-epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 475.0
WH2_k127_24607_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 353.0
WH2_k127_24607_2 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 292.0
WH2_k127_24607_3 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000991 135.0
WH2_k127_2518337_0 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 576.0
WH2_k127_2518337_1 Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 340.0
WH2_k127_2518337_2 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000000000000000000000001456 198.0
WH2_k127_2536788_0 Cell division protein ftsk K03466 - - 2.738e-266 823.0
WH2_k127_2536788_1 AbgT putative transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 562.0
WH2_k127_2536788_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000002842 168.0
WH2_k127_2542245_0 Belongs to the aldehyde dehydrogenase family K00146,K09472 - 1.2.1.39,1.2.1.99 8.646e-266 824.0
WH2_k127_2542245_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 335.0
WH2_k127_2542245_2 Phage-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 303.0
WH2_k127_2542245_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008461 269.0
WH2_k127_2545108_0 nadh pyrophosphatase K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009441 275.0
WH2_k127_2545108_1 Membrane protein required for beta-lactamase induction K03807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000037 253.0
WH2_k127_2545108_2 Iron-sulfur cluster insertion protein ErpA K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000006302 200.0
WH2_k127_2545108_3 - - - - 0.0000000000000000000000000000000000001258 144.0
WH2_k127_2545108_4 cell shape determination - - - 0.0000000000000000000000000000000000004649 143.0
WH2_k127_2602070_0 Involved in the TonB-independent uptake of proteins K03641 - - 1.659e-201 634.0
WH2_k127_2602070_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 563.0
WH2_k127_2602070_2 TolQ protein K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 356.0
WH2_k127_2602070_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 338.0
WH2_k127_2602070_4 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001368 256.0
WH2_k127_2602070_5 Membrane protein TolA K03646 - - 0.0000000000000000000000000000000000000000000000000000000000007615 220.0
WH2_k127_2602070_6 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000008875 196.0
WH2_k127_2602070_7 Biopolymer transport protein K03560 - - 0.0000000000000000000000000000000000000000000000000001955 188.0
WH2_k127_2602070_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000007457 192.0
WH2_k127_2602070_9 Acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000000000000003235 161.0
WH2_k127_2709272_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1358.0
WH2_k127_2709272_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 561.0
WH2_k127_2709272_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 537.0
WH2_k127_2709272_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 380.0
WH2_k127_2709272_4 COG0457 FOG TPR repeat - - - 0.0000000000007521 78.0
WH2_k127_2721323_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.642e-266 840.0
WH2_k127_2721323_1 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 360.0
WH2_k127_2721323_2 Helicase K03578 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000001259 207.0
WH2_k127_2721323_3 - - - - 0.0000000000000000000003236 105.0
WH2_k127_2723486_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 335.0
WH2_k127_2723486_1 Lipoprotein - - - 0.000000000000000000000000000000000000000000000000000005232 196.0
WH2_k127_2745717_0 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 494.0
WH2_k127_2745717_1 transcriptional regulator K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000001634 203.0
WH2_k127_2745717_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000004428 154.0
WH2_k127_2757818_0 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1408.0
WH2_k127_2757818_1 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 542.0
WH2_k127_276169_0 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 556.0
WH2_k127_276169_1 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000001126 226.0
WH2_k127_276169_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000001544 109.0
WH2_k127_2771780_0 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 578.0
WH2_k127_2771780_1 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 289.0
WH2_k127_2771780_2 Conserved Protein - - - 0.00000000000000003643 89.0
WH2_k127_28299_0 Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1887.0
WH2_k127_28299_1 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 3.035e-198 622.0
WH2_k127_28299_2 Single-stranded-DNA-specific exonuclease K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 303.0
WH2_k127_28299_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000483 240.0
WH2_k127_28299_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.000000000000000000000000000001398 121.0
WH2_k127_28299_5 Protein conserved in bacteria - - - 0.0000000000000000000000000007512 121.0
WH2_k127_28299_6 Protein conserved in bacteria - - - 0.000000000000000000000008988 106.0
WH2_k127_288981_0 Major facilitator superfamily K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 464.0
WH2_k127_288981_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.00000000000000000000000000000000000000000000000000000003404 199.0
WH2_k127_2902519_0 peptidase - - - 0.0 1021.0
WH2_k127_2902519_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11745,K11747 - - 2.701e-202 646.0
WH2_k127_2902519_2 ankyrin repeat K06867 - - 1.668e-196 649.0
WH2_k127_2902519_3 YcgL domain-containing protein K09902 - - 0.0000000000000000000000000002444 116.0
WH2_k127_2997950_0 Cystathionine beta-synthase K01697 - 4.2.1.22 9.573e-259 801.0
WH2_k127_2997950_1 cystathionine K01758 - 4.4.1.1 5.896e-207 647.0
WH2_k127_2997950_2 transferase K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 404.0
WH2_k127_2997950_3 transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 373.0
WH2_k127_2997950_4 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000004419 205.0
WH2_k127_2997950_5 membrane - - - 0.00000000000000000000000007559 114.0
WH2_k127_2997950_6 Protein of unknown function (DUF465) - - - 0.0000000000000000000001271 99.0
WH2_k127_3049031_0 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 4.011e-200 627.0
WH2_k127_3049031_1 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002125 271.0
WH2_k127_3049031_2 MarR family transcriptional regulator - - - 0.00000000000000000000000000000007171 129.0
WH2_k127_3080374_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 459.0
WH2_k127_3080374_1 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 454.0
WH2_k127_3080374_10 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000002329 124.0
WH2_k127_3080374_11 phosphocarrier protein HPr K11189 - - 0.000000000000000000001468 96.0
WH2_k127_3080374_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 430.0
WH2_k127_3080374_3 abc transporter atp-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 375.0
WH2_k127_3080374_4 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 362.0
WH2_k127_3080374_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006054 292.0
WH2_k127_3080374_6 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000004433 203.0
WH2_k127_3080374_7 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.0000000000000000000000000000000000000000001594 165.0
WH2_k127_3080374_8 modulation protein K05808 - - 0.00000000000000000000000000000000000000003082 154.0
WH2_k127_3080374_9 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.0000000000000000000000000000000000001756 146.0
WH2_k127_311028_0 glutamate dehydrogenase K15371 - 1.4.1.2 3.344e-318 987.0
WH2_k127_3176456_0 Belongs to the FBPase class 1 family K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 578.0
WH2_k127_3176456_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 529.0
WH2_k127_3176456_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 339.0
WH2_k127_3176456_3 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 308.0
WH2_k127_3176456_4 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000136 133.0
WH2_k127_3176456_5 - - - - 0.000005126 52.0
WH2_k127_31770_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 571.0
WH2_k127_31770_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 348.0
WH2_k127_31770_2 RNA-binding protein K07574 - - 0.00000000000000000000000000000000000003636 148.0
WH2_k127_31770_3 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000009335 91.0
WH2_k127_3181803_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1314.0
WH2_k127_3181803_1 E3 component of 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 3.53e-238 743.0
WH2_k127_3181803_10 Glycine zipper 2TM domain - - - 0.000000000000000000114 93.0
WH2_k127_3181803_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 574.0
WH2_k127_3181803_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 421.0
WH2_k127_3181803_4 Quinone oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 413.0
WH2_k127_3181803_5 Cytochrome C biogenesis protein K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 358.0
WH2_k127_3181803_6 Peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000001154 231.0
WH2_k127_3181803_7 Chemotaxis protein CheY K02658 - - 0.00000000000000000000000000000000000000000000000000000000002673 207.0
WH2_k127_3181803_8 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.0000000000000000000000000000000000000000003817 159.0
WH2_k127_3181803_9 - - - - 0.00000000000000000000000000000000000002737 151.0
WH2_k127_3197955_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 1.885e-219 686.0
WH2_k127_3197955_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 544.0
WH2_k127_3197955_2 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 389.0
WH2_k127_3197955_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001898 254.0
WH2_k127_3297980_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 3.146e-219 683.0
WH2_k127_3297980_1 Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 361.0
WH2_k127_3297980_2 Prolyl 4-hydroxylase alpha subunit homologues. K00472,K07126 - 1.14.11.2 0.00000000000000000000000000000000000495 142.0
WH2_k127_3403497_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 492.0
WH2_k127_3403497_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000273 247.0
WH2_k127_3403497_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000005417 197.0
WH2_k127_3411879_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 1.166e-297 928.0
WH2_k127_3411879_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 8.991e-220 690.0
WH2_k127_3411879_2 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 499.0
WH2_k127_3411879_3 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000003071 258.0
WH2_k127_3411879_4 - - - - 0.0000000000000000000000000000000000000000000000000000004288 198.0
WH2_k127_3411879_5 - - - - 0.00000000000000000000002128 104.0
WH2_k127_3411879_6 phosphoglycerate mutase - - - 0.000000000000002759 83.0
WH2_k127_3411879_7 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000771 76.0
WH2_k127_3471531_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1140.0
WH2_k127_3471531_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000005166 108.0
WH2_k127_3471531_2 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.00000000000000000002278 92.0
WH2_k127_3629503_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 442.0
WH2_k127_3629503_1 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 435.0
WH2_k127_3679680_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 559.0
WH2_k127_3679680_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 464.0
WH2_k127_3679680_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 336.0
WH2_k127_3679680_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000002746 236.0
WH2_k127_3679680_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000006406 209.0
WH2_k127_3679680_5 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.0000000000000000000000000000000000000002157 153.0
WH2_k127_3679680_6 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000002576 140.0
WH2_k127_3679680_7 PDZ domain - - - 0.000000000000000000000000000007569 133.0
WH2_k127_3679680_8 - - - - 0.000000000001642 75.0
WH2_k127_3697361_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1093.0
WH2_k127_3697361_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 332.0
WH2_k127_3697361_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000001571 123.0
WH2_k127_3697361_3 Domain of unknown function (DUF4845) - - - 0.000000000000000000000002111 108.0
WH2_k127_3697361_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000003326 62.0
WH2_k127_3697790_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 357.0
WH2_k127_3697790_1 Drug metabolite transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000004193 246.0
WH2_k127_3697790_2 Acetyltransferase (GNAT) domain K02348 - - 0.0000000000000000000000000000000000000000000007804 171.0
WH2_k127_3701660_0 chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 387.0
WH2_k127_3701660_1 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 385.0
WH2_k127_3701660_2 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 373.0
WH2_k127_3701660_3 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 325.0
WH2_k127_3701660_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008734 271.0
WH2_k127_3701660_5 Dolichol-phosphate mannosyltransferase K00721 - 2.4.1.83 0.00000000000005313 75.0
WH2_k127_3701660_6 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00001275 47.0
WH2_k127_3703830_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 4.661e-198 627.0
WH2_k127_3703830_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 458.0
WH2_k127_3703830_2 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002006 265.0
WH2_k127_3703830_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000001319 234.0
WH2_k127_3746194_0 Aminotransferase K14260 - 2.6.1.2,2.6.1.66 2.413e-197 621.0
WH2_k127_3746194_1 glutathione s-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001656 278.0
WH2_k127_3746194_2 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000000002318 171.0
WH2_k127_3787517_0 phosphate transporter K03306 - - 1.806e-195 614.0
WH2_k127_3787517_1 peptidase K07386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 409.0
WH2_k127_3787517_2 Pit accessory protein K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 345.0
WH2_k127_3787517_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004064 278.0
WH2_k127_3787517_4 Hemolysins and related proteins containing CBS domains K03699 - - 0.00000000000000000000000000000000000001202 148.0
WH2_k127_3787517_5 Cysteine methyltransferase K07443 - - 0.00000000000000000000000000000004245 130.0
WH2_k127_3787517_6 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 - - 0.00000000000000000003705 102.0
WH2_k127_3838479_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 398.0
WH2_k127_3838479_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 377.0
WH2_k127_3838479_2 stress-induced protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 350.0
WH2_k127_3838479_3 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 318.0
WH2_k127_3838479_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000001629 252.0
WH2_k127_3838479_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000002032 182.0
WH2_k127_3838479_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000403 139.0
WH2_k127_3922945_0 Synthesizes selenophosphate from selenide and ATP K01008 GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 495.0
WH2_k127_3922945_1 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 430.0
WH2_k127_3937430_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.64e-196 624.0
WH2_k127_3937430_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 384.0
WH2_k127_3998573_0 NADH ubiquinone oxidoreductase subunit K00341 - 1.6.5.3 1e-323 1002.0
WH2_k127_3998573_1 NADH-quinone oxidoreductase K00336 - 1.6.5.3 8.392e-270 844.0
WH2_k127_3998573_2 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 2.233e-247 771.0
WH2_k127_3998573_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 591.0
WH2_k127_3998573_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 308.0
WH2_k127_3998573_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000019 247.0
WH2_k127_3998573_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000003882 164.0
WH2_k127_4019546_0 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 399.0
WH2_k127_4019546_1 acetyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 357.0
WH2_k127_4019546_2 Cardiolipin synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 307.0
WH2_k127_4019546_3 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005495 243.0
WH2_k127_4019546_4 Tetratricopeptide TPR_2 repeat protein - - - 0.000009703 55.0
WH2_k127_4025676_0 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 550.0
WH2_k127_4025676_1 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 405.0
WH2_k127_4025676_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 323.0
WH2_k127_4025676_3 Catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate K22292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000001278 242.0
WH2_k127_4025676_4 Phytoene synthase - - - 0.0000000000000000000000000000000001053 142.0
WH2_k127_4025676_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000001734 124.0
WH2_k127_4025676_6 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000747 47.0
WH2_k127_4029092_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1083.0
WH2_k127_4029092_1 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.000000000000000000000000000000000003505 139.0
WH2_k127_4029092_2 Cold shock protein domain - - - 0.000000000000000000000000000000001292 130.0
WH2_k127_4029092_3 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000008708 108.0
WH2_k127_4071588_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 1.675e-226 706.0
WH2_k127_4071588_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 553.0
WH2_k127_4071588_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) - - - 0.0000000000000000000000000000000000000000000000000000000000001324 218.0
WH2_k127_4071588_3 Hydrolase K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000000002324 193.0
WH2_k127_4071588_4 rubredoxin - - - 0.000000000000000000000000001823 112.0
WH2_k127_4071588_5 Transglutaminase-like superfamily - - - 0.0000000000000000001176 89.0
WH2_k127_4071588_6 - - - - 0.0000000000001016 75.0
WH2_k127_4083822_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 596.0
WH2_k127_4083822_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 383.0
WH2_k127_4083822_2 stringent starvation protein A K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 289.0
WH2_k127_4083822_3 cytochrome K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003964 269.0
WH2_k127_4083822_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000009891 245.0
WH2_k127_4083822_5 stringent starvation protein b K03600 - - 0.0000000000000000000000000000000000000000001001 164.0
WH2_k127_4083822_6 Protein of unknown function (DUF3301) - - - 0.000000000000000000001061 98.0
WH2_k127_4083822_7 Trm112p-like protein - - - 0.00000000000000000001168 93.0
WH2_k127_4100378_0 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 523.0
WH2_k127_4100378_1 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 382.0
WH2_k127_4100378_2 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000002158 214.0
WH2_k127_4100378_3 cytochrome - - - 0.0000000000204 67.0
WH2_k127_4100378_4 - - - - 0.000000004646 61.0
WH2_k127_4134271_0 aconitate hydratase K20455 - 4.2.1.117 0.0 1456.0
WH2_k127_4134271_1 AcnD-accessory protein PrpF K09788 - - 0.0004362 43.0
WH2_k127_4178719_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 383.0
WH2_k127_4178719_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 348.0
WH2_k127_4178719_2 LemA Family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003871 250.0
WH2_k127_4178719_3 - - - - 0.000000000000000000000000000000000000000000002177 176.0
WH2_k127_4193047_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.243e-232 733.0
WH2_k127_4193047_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 547.0
WH2_k127_4193047_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 445.0
WH2_k127_4193047_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 323.0
WH2_k127_4193047_4 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002955 255.0
WH2_k127_4193047_5 - - - - 0.0000000000000000000000000000000000006125 147.0
WH2_k127_4193047_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000002104 96.0
WH2_k127_4207705_0 aminotransferase K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 502.0
WH2_k127_4207705_1 carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 364.0
WH2_k127_4207705_2 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 314.0
WH2_k127_4221507_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 452.0
WH2_k127_4221507_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000004986 228.0
WH2_k127_4221507_2 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.000000000000000000000000000000000000000000000000000000002512 207.0
WH2_k127_4269411_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 408.0
WH2_k127_4269411_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000001485 164.0
WH2_k127_4269411_2 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000004308 145.0
WH2_k127_4269411_3 - - - - 0.000000000000000000000000002759 112.0
WH2_k127_4269411_4 Protein of unknown function (DUF2892) - - - 0.000000000000000000007122 94.0
WH2_k127_4269411_5 - - - - 0.00000000000003711 76.0
WH2_k127_4281483_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.516e-224 702.0
WH2_k127_4281483_1 Mur ligase family, glutamate ligase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 506.0
WH2_k127_4281483_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 304.0
WH2_k127_4281483_3 Belongs to the Fur family K09823 - - 0.00000000000000000000000000000000000000000000000000000000000000007358 228.0
WH2_k127_4281483_4 GNAT family acetyltransferase K03802 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000003468 192.0
WH2_k127_4281483_5 Domain of unknown function (DUF4870) - - - 0.0000000000000000000000002628 110.0
WH2_k127_4287034_0 ABC-type multidrug transport system ATPase component K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 298.0
WH2_k127_4287034_1 ABC-2 family transporter protein - - - 0.000000000000000000000001604 108.0
WH2_k127_4287034_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000001278 65.0
WH2_k127_4303757_0 dna polymerase K02337 - 2.7.7.7 1.961e-222 699.0
WH2_k127_4303757_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000004214 148.0
WH2_k127_4320184_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 431.0
WH2_k127_4320184_1 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000006901 174.0
WH2_k127_4320184_2 With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate K03154 - - 0.000000000000002283 78.0
WH2_k127_434734_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 6.404e-221 689.0
WH2_k127_434734_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 496.0
WH2_k127_434734_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 312.0
WH2_k127_434734_3 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000003409 199.0
WH2_k127_434734_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000004012 100.0
WH2_k127_4365939_0 Helicase K03722 - 3.6.4.12 1.966e-255 804.0
WH2_k127_4365939_1 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 5.202e-201 636.0
WH2_k127_4365939_2 glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000002796 206.0
WH2_k127_4365939_3 Protein of unknown function (DUF1294) - - - 0.000000000000000000000003345 106.0
WH2_k127_4365939_4 Tetratricopeptide repeat - - - 0.00000000000000000000001601 106.0
WH2_k127_4406413_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 9.43e-261 809.0
WH2_k127_4406413_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
WH2_k127_4406413_2 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000005055 251.0
WH2_k127_4406413_3 protein conserved in bacteria - - - 0.0000000000000000004149 89.0
WH2_k127_4406413_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0001254 46.0
WH2_k127_4406806_0 Alpha amylase, catalytic domain K01187,K01208,K21575 - 3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54 3.599e-276 861.0
WH2_k127_4406806_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 392.0
WH2_k127_4406806_2 DNA mediated transformation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 325.0
WH2_k127_4406806_3 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000004816 249.0
WH2_k127_4411025_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.222e-266 824.0
WH2_k127_4411025_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 458.0
WH2_k127_4411025_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000002395 51.0
WH2_k127_4418158_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.564e-298 922.0
WH2_k127_4418158_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 447.0
WH2_k127_4418158_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 374.0
WH2_k127_4418158_3 Threonine/Serine exporter, ThrE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001422 281.0
WH2_k127_4418158_4 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000332 243.0
WH2_k127_44738_0 Involved in the processing of the 5'end of 16S rRNA K08301 - - 6.207e-228 714.0
WH2_k127_44738_1 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 593.0
WH2_k127_44738_2 dna polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001118 276.0
WH2_k127_44738_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000002319 258.0
WH2_k127_44738_4 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000002929 241.0
WH2_k127_44738_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000000000000000000003081 234.0
WH2_k127_44738_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000186 199.0
WH2_k127_4485262_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1239.0
WH2_k127_4496431_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 552.0
WH2_k127_4496431_1 peptidase M20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 517.0
WH2_k127_4496431_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001844 239.0
WH2_k127_4496431_3 HutD K09975 - - 0.000000000000000000000000000000000000000000000007378 178.0
WH2_k127_4496431_4 Benzene 1,2-dioxygenase K05710 - - 0.00000000000000000000000000000000000000002807 154.0
WH2_k127_4496431_5 competence protein ComEA K02237 - - 0.000000000000000000003552 96.0
WH2_k127_4511955_0 Cytochrome C biogenesis K02198 - - 1.465e-287 896.0
WH2_k127_4511955_1 Thiol disulfide interchange protein K02199 - - 0.00000000000000000000000000000000000000000000000000000002266 199.0
WH2_k127_4511955_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000002084 102.0
WH2_k127_4512102_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 6.749e-250 776.0
WH2_k127_4512102_1 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000008951 146.0
WH2_k127_4512102_2 ABC transporter substrate-binding protein K02067 - - 0.00000000000000000000000000004168 120.0
WH2_k127_4517145_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.008e-311 958.0
WH2_k127_4517145_1 Thiol disulfide Interchange Protein K04084 - 1.8.1.8 6.537e-238 754.0
WH2_k127_4517145_2 Transcriptional regulatory protein, C terminal K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 288.0
WH2_k127_4517145_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000004184 198.0
WH2_k127_4517145_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000007862 179.0
WH2_k127_4517145_5 PAS fold - - - 0.0000000000000000000000000000000000000000101 158.0
WH2_k127_4517145_6 - - - - 0.0000000006636 68.0
WH2_k127_4531590_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.148e-200 634.0
WH2_k127_4531590_1 Acetyl-CoA dehydrogenase C-terminal like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 593.0
WH2_k127_4531590_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 486.0
WH2_k127_4531590_3 murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 380.0
WH2_k127_4531590_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 319.0
WH2_k127_4531590_5 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000006496 258.0
WH2_k127_4572584_0 Cysteine desulfurase activator complex subunit SufB K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 561.0
WH2_k127_4572584_1 Phospholipid-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000362 269.0
WH2_k127_4572584_2 SET domain K07117 - - 0.00000000000000000000000000000000000000000000000000000000000000000001752 237.0
WH2_k127_4572584_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000002288 211.0
WH2_k127_4670304_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 417.0
WH2_k127_4670304_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 337.0
WH2_k127_4670304_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003402 272.0
WH2_k127_4670304_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000007544 219.0
WH2_k127_4670304_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000002508 95.0
WH2_k127_4713740_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 540.0
WH2_k127_4713740_1 multicopper - - - 0.0000000000000000000000000000000000000000000002178 169.0
WH2_k127_4775211_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002276 288.0
WH2_k127_4775211_1 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000001277 175.0
WH2_k127_4775211_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000007273 159.0
WH2_k127_4775211_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000003092 62.0
WH2_k127_4775714_0 Serine dehydratase K01752 - 4.3.1.17 1.704e-237 740.0
WH2_k127_4775714_1 MASE1 - - - 2.696e-209 669.0
WH2_k127_4775714_2 thiol-disulfide isomerase and - - - 0.000000000000000002783 86.0
WH2_k127_4844330_0 AMP-binding enzyme C-terminal domain K20034 - 6.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 506.0
WH2_k127_4844330_1 glutathione transferase activity K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 290.0
WH2_k127_4844330_2 sterol desaturase - - - 0.00000000000000000000000000000000000000000006674 162.0
WH2_k127_4844330_3 - - - - 0.00000000000000000000000000000000000003134 149.0
WH2_k127_4844330_4 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000000000000003994 125.0
WH2_k127_4845218_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1197.0
WH2_k127_4845218_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 482.0
WH2_k127_4845218_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 321.0
WH2_k127_4845218_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001269 278.0
WH2_k127_4845218_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000008073 227.0
WH2_k127_4845218_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000306 75.0
WH2_k127_4846548_0 Transporter K03305 - - 3.122e-240 750.0
WH2_k127_4846548_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 609.0
WH2_k127_4846548_2 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 586.0
WH2_k127_4846548_3 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 558.0
WH2_k127_4846548_4 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 434.0
WH2_k127_4846548_5 Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 353.0
WH2_k127_4846548_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000001607 182.0
WH2_k127_4846548_7 Cysteine-rich CWC - - - 0.00000000000000001131 83.0
WH2_k127_4891826_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 414.0
WH2_k127_4891826_1 ABC transporter K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 327.0
WH2_k127_4891826_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 310.0
WH2_k127_4891826_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 306.0
WH2_k127_4897808_0 Dienelactone hydrolase family - - - 1.066e-282 882.0
WH2_k127_4897808_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 2.789e-251 786.0
WH2_k127_4897808_10 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000521 129.0
WH2_k127_4897808_11 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000008245 115.0
WH2_k127_4897808_12 signal sequence binding - - - 0.0000000000526 64.0
WH2_k127_4897808_2 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 522.0
WH2_k127_4897808_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 506.0
WH2_k127_4897808_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 448.0
WH2_k127_4897808_5 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 347.0
WH2_k127_4897808_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000001025 214.0
WH2_k127_4897808_7 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000003405 203.0
WH2_k127_4897808_8 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000001723 192.0
WH2_k127_4897808_9 Glutamyl-tRNA amidotransferase K09117 - - 0.000000000000000000000000000000000000000000000000000003094 194.0
WH2_k127_4915599_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 534.0
WH2_k127_4915599_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 323.0
WH2_k127_4915599_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000001058 153.0
WH2_k127_4915599_3 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000007134 85.0
WH2_k127_4929105_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 497.0
WH2_k127_4929105_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 384.0
WH2_k127_4929105_2 Nucleoside triphosphate K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 296.0
WH2_k127_4929105_3 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000000000003835 156.0
WH2_k127_4929105_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000131 71.0
WH2_k127_4929574_0 Sulfatase K03760 - 2.7.8.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 509.0
WH2_k127_4929574_1 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000001215 175.0
WH2_k127_4929574_2 Amidohydrolase family - - - 0.00000000000000000000000000000000003337 141.0
WH2_k127_4929574_3 membrane - - - 0.000000000000000000000000000000004058 131.0
WH2_k127_4929574_4 PAP2 superfamily - - - 0.00000000000000000000000000001332 126.0
WH2_k127_4933367_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 3.699e-272 842.0
WH2_k127_4933367_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 464.0
WH2_k127_4933367_2 Belongs to the phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 323.0
WH2_k127_4939192_0 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 587.0
WH2_k127_4939192_1 Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000001562 184.0
WH2_k127_4940502_0 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 464.0
WH2_k127_4940502_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 407.0
WH2_k127_4940502_2 Protein of unknown function (DUF971) - - - 0.00000000001568 64.0
WH2_k127_4988684_0 Histidine kinase - - - 2.129e-242 790.0
WH2_k127_4988684_1 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 383.0
WH2_k127_4988684_2 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002552 268.0
WH2_k127_5006576_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 1.61e-197 617.0
WH2_k127_5006576_1 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 518.0
WH2_k127_5006576_2 aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000001698 156.0
WH2_k127_5006576_3 Protein of unknown function (DUF3224) - - - 0.0000000000000000000000000000000000005802 143.0
WH2_k127_5006576_4 - - - - 0.00000000000000000000000008651 113.0
WH2_k127_5038467_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.317e-247 767.0
WH2_k127_5038467_1 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008669 270.0
WH2_k127_5038467_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.00000000000000000000000000000000000000000000000000000000004952 208.0
WH2_k127_5038467_3 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000222 209.0
WH2_k127_5038467_4 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000000004231 149.0
WH2_k127_5051857_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 516.0
WH2_k127_5051857_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 447.0
WH2_k127_5051857_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 389.0
WH2_k127_5051857_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 356.0
WH2_k127_5051857_4 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 346.0
WH2_k127_5051857_5 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 316.0
WH2_k127_5051857_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 289.0
WH2_k127_5051857_7 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000004601 247.0
WH2_k127_5051857_8 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000001201 170.0
WH2_k127_5051857_9 Protein of unknown function (DUF861) K06995 - - 0.00000000000000000000000000000000799 130.0
WH2_k127_5053273_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 610.0
WH2_k127_5053273_1 pseudouridylate synthase K06175 - 5.4.99.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 344.0
WH2_k127_5053273_2 3-beta hydroxysteroid dehydrogenase K22320 - 1.1.1.412 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 318.0
WH2_k127_5053273_3 Sterol-binding protein K03690 - - 0.000000000000000000000000000000000000000000000000000000003185 205.0
WH2_k127_5098641_0 Protein of unknown function (DUF1302) - - - 4.016e-256 807.0
WH2_k127_5098641_1 Sodium:sulfate symporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 527.0
WH2_k127_5098641_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 415.0
WH2_k127_5100755_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 468.0
WH2_k127_5100755_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000000000000001549 209.0
WH2_k127_5100755_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000008905 78.0
WH2_k127_5100755_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000009024 72.0
WH2_k127_5111469_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 332.0
WH2_k127_5111469_1 Phosphate starvation protein PhoH K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 310.0
WH2_k127_5111469_2 DnaJ molecular chaperone homology domain K05516 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.0003809 52.0
WH2_k127_5117673_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 590.0
WH2_k127_5117673_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 573.0
WH2_k127_5117673_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 433.0
WH2_k127_5117673_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 425.0
WH2_k127_5117673_4 Penicillin-insensitive murein endopeptidase K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 358.0
WH2_k127_5117673_5 Belongs to the ArsC family - - - 0.000000000000000000000000000000000000000002575 157.0
WH2_k127_5117673_6 membrane - - - 0.000000000000000000000000000000000000003251 149.0
WH2_k127_5182479_0 abc transporter atp-binding protein K06158 - - 1.281e-311 964.0
WH2_k127_5182479_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 445.0
WH2_k127_5182479_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 396.0
WH2_k127_5182479_3 Protein of unknown function (DUF3011) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 331.0
WH2_k127_5182479_4 beta-lactamase K01467 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000002983 257.0
WH2_k127_5182479_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000005263 230.0
WH2_k127_5182479_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000005773 187.0
WH2_k127_5182479_7 Regulatory protein, FmdB family - - - 0.0000000000000000000000000000000001223 133.0
WH2_k127_518249_0 acyl-coa dehydrogenase - - - 1.117e-267 834.0
WH2_k127_5187184_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 416.0
WH2_k127_5187184_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000002531 212.0
WH2_k127_5233980_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 306.0
WH2_k127_5233980_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 287.0
WH2_k127_5233980_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000005804 223.0
WH2_k127_5233980_3 phosphatase K20074 - 3.1.3.16 0.0000000001211 68.0
WH2_k127_5233980_4 Methyl-transferase - - - 0.00000001085 64.0
WH2_k127_5237399_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 339.0
WH2_k127_5237399_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 340.0
WH2_k127_5237399_2 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.000000000000000000000000000000000000000000000000000000002293 208.0
WH2_k127_5247781_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 547.0
WH2_k127_5247781_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 287.0
WH2_k127_5247781_2 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000002973 187.0
WH2_k127_5247781_3 Competence protein - GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000151 172.0
WH2_k127_5247781_4 Predicted membrane protein (DUF2306) - - - 0.000000000000000000000000000000000000000004534 159.0
WH2_k127_5278259_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 369.0
WH2_k127_5278259_1 phenazine biosynthesis protein PhzF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 350.0
WH2_k127_5278259_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000002615 238.0
WH2_k127_5278259_3 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000009657 227.0
WH2_k127_5278259_4 Glycine zipper 2TM domain - - - 0.00000000000000000000002404 106.0
WH2_k127_5282288_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 8.708e-224 700.0
WH2_k127_5282288_1 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 6.711e-195 617.0
WH2_k127_5282288_2 Nucleoprotein polynucleotide-associated enzyme K09912 - - 0.000000000000000000000000000000000000000001905 162.0
WH2_k127_5282288_3 Belongs to the SlyX family K03745 - - 0.0000000000000004758 79.0
WH2_k127_5378371_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 346.0
WH2_k127_5378371_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 306.0
WH2_k127_5378371_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 307.0
WH2_k127_5378371_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005311 261.0
WH2_k127_5378371_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000001675 122.0
WH2_k127_5378371_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000001325 114.0
WH2_k127_5378371_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03425 GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000003974 73.0
WH2_k127_5391615_0 Major facilitator superfamily K16211 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 512.0
WH2_k127_5391615_1 esterase K12686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 423.0
WH2_k127_5391615_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000008895 207.0
WH2_k127_5391615_3 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000000000000009286 139.0
WH2_k127_5391615_4 reverse transcriptase - - - 0.000000000001813 72.0
WH2_k127_5401551_0 Protein of unknown function (DUF1329) - - - 3.92e-230 718.0
WH2_k127_5401551_1 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 325.0
WH2_k127_5401551_2 MMPL family - - - 0.0000000000001219 72.0
WH2_k127_5425349_0 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 4.218e-194 611.0
WH2_k127_5425349_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 541.0
WH2_k127_5425349_2 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 444.0
WH2_k127_5425349_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 440.0
WH2_k127_5425349_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 389.0
WH2_k127_5425349_5 - - - - 0.00000000000000000000000000000000000000000000000000000000004882 213.0
WH2_k127_5425349_6 polyhydroxyalkanoic acid - - - 0.00000000000000000000000000008675 128.0
WH2_k127_5425349_7 FHA domain - - - 0.000000000000000005054 94.0
WH2_k127_5441270_0 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 404.0
WH2_k127_5441270_1 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.00000000000000000001932 92.0
WH2_k127_5471546_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.352e-261 810.0
WH2_k127_5471546_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 361.0
WH2_k127_5471546_2 dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 339.0
WH2_k127_5481058_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 9.106e-285 895.0
WH2_k127_5481058_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 7.868e-261 805.0
WH2_k127_5481058_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 8.381e-260 818.0
WH2_k127_5481058_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 524.0
WH2_k127_5481058_4 Pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 482.0
WH2_k127_5481058_5 Belongs to the IUNH family K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 431.0
WH2_k127_5481058_6 endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000002563 188.0
WH2_k127_5481058_7 assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000003183 179.0
WH2_k127_5481058_8 Ribosomal protein L31 K02909 - - 0.000000000000000000000000000000000000004164 147.0
WH2_k127_5491139_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1138.0
WH2_k127_5491139_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.643e-301 931.0
WH2_k127_5491139_10 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000002867 99.0
WH2_k127_5491139_11 - - - - 0.0000000000000001445 87.0
WH2_k127_5491139_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 6.512e-227 707.0
WH2_k127_5491139_3 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 505.0
WH2_k127_5491139_4 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 398.0
WH2_k127_5491139_5 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000017 276.0
WH2_k127_5491139_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000005981 246.0
WH2_k127_5491139_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000002269 235.0
WH2_k127_5491139_8 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000000000000000000000000376 172.0
WH2_k127_5491139_9 SMR domain protein - - - 0.000000000000000000000000000000000000008456 151.0
WH2_k127_5648350_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 509.0
WH2_k127_5648350_1 Bacterial protein of unknown function (DUF922) - - - 0.000000000000000006256 89.0
WH2_k127_5648350_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.0000000000002651 72.0
WH2_k127_5648350_3 PFAM VanZ - - - 0.00000000001009 71.0
WH2_k127_5667021_0 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 562.0
WH2_k127_5667021_1 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000198 280.0
WH2_k127_5667021_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000003934 184.0
WH2_k127_5670239_0 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 520.0
WH2_k127_5670239_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 424.0
WH2_k127_5670239_2 Hydrolase K20862 - 3.1.3.102,3.1.3.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001736 272.0
WH2_k127_5670239_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000006226 62.0
WH2_k127_56802_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 5.99e-208 651.0
WH2_k127_56802_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 451.0
WH2_k127_56802_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 406.0
WH2_k127_56802_3 YCII-related domain - - - 0.000000000000000000003864 98.0
WH2_k127_5685170_0 Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol K03184,K18800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 391.0
WH2_k127_5685170_1 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 352.0
WH2_k127_5685170_2 hydroxylase K03185 - - 0.00000000000000000000000000005573 119.0
WH2_k127_5685170_3 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.00000105 51.0
WH2_k127_5737406_0 Autotransporter beta-domain - - - 0.0000000000000000000000000000000000000000000000000000000000000379 238.0
WH2_k127_5783894_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.359e-243 769.0
WH2_k127_5783894_1 Tryptophan halogenase K14266 - 1.14.19.9 1.086e-209 667.0
WH2_k127_5783894_2 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 603.0
WH2_k127_5783894_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 582.0
WH2_k127_5783894_4 Putative esterase - - - 0.000000000000000000000000000000000000009111 151.0
WH2_k127_5783894_5 - - - - 0.00000000000000001361 94.0
WH2_k127_5784449_0 receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 349.0
WH2_k127_5784449_1 Protein of unknown function (DUF1631) - - - 0.000000000000000000000001137 117.0
WH2_k127_5789386_0 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 327.0
WH2_k127_5849109_0 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 0.0 1030.0
WH2_k127_5849109_1 Inhibitor of apoptosis-promoting Bax1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 335.0
WH2_k127_5849109_2 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 297.0
WH2_k127_5849109_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001204 254.0
WH2_k127_5884514_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 586.0
WH2_k127_5884514_1 Lytic murein transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 434.0
WH2_k127_5884514_2 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 314.0
WH2_k127_5884514_3 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001279 265.0
WH2_k127_5884514_4 Bacterial protein of unknown function (DUF922) - - - 0.00000000000000000000000003856 114.0
WH2_k127_5884514_5 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000002838 104.0
WH2_k127_5889496_0 twitching motility protein K02670 - - 7.546e-205 641.0
WH2_k127_5889496_1 2-keto-4-pentenoate hydratase K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 554.0
WH2_k127_5889496_2 maleylacetoacetate isomerase K01800 - 5.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001 248.0
WH2_k127_5889496_3 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.000000000000000000000000000000000001255 139.0
WH2_k127_5889496_4 membrane - - - 0.0000315 50.0
WH2_k127_5890643_0 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 368.0
WH2_k127_5890643_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 354.0
WH2_k127_5890643_2 Belongs to the UPF0176 family K07146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 301.0
WH2_k127_5890643_3 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 0.00000000000000000000000000000000000000000000000000003047 193.0
WH2_k127_5890643_4 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000001332 176.0
WH2_k127_5890643_5 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000004627 129.0
WH2_k127_5895123_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 350.0
WH2_k127_5895123_1 Amino-transferase class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 293.0
WH2_k127_5895123_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000005165 198.0
WH2_k127_5895123_3 component I K01657 - 4.1.3.27 0.00000000005319 63.0
WH2_k127_5912731_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 425.0
WH2_k127_5912731_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000007524 152.0
WH2_k127_5912731_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000023 130.0
WH2_k127_5912731_3 TfoX N-terminal domain K07343 - - 0.0000000000000000000001613 101.0
WH2_k127_5928029_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 505.0
WH2_k127_5928029_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001956 273.0
WH2_k127_5928029_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000001906 242.0
WH2_k127_5928029_3 peptidase - - - 0.00000000000000000000000000000000000000000000000001028 184.0
WH2_k127_5928029_4 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000003081 114.0
WH2_k127_5929237_0 2,4-dienoyl-coa reductase K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 601.0
WH2_k127_5929237_1 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 342.0
WH2_k127_5929237_2 synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000001076 232.0
WH2_k127_5929237_3 - - - - 0.00000002298 62.0
WH2_k127_6067196_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 320.0
WH2_k127_6067196_1 Belongs to the bacterial solute-binding protein 9 family - - - 0.00000000000000000000000000000000000000000000000000000002816 203.0
WH2_k127_6067196_2 PIN domain - - - 0.00000000000000000000000000000000000000009625 153.0
WH2_k127_6067196_3 SpoVT / AbrB like domain - - - 0.00000000000000000006798 91.0
WH2_k127_6067196_4 Adenylate cyclase - - - 0.000005769 48.0
WH2_k127_6091100_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.476e-248 773.0
WH2_k127_6091100_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 497.0
WH2_k127_6091100_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 486.0
WH2_k127_6091100_3 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 352.0
WH2_k127_6091100_4 Transcriptional regulator K10914 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0017076,GO:0019001,GO:0019219,GO:0019222,GO:0030551,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032561,GO:0035438,GO:0036094,GO:0043167,GO:0043168,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 338.0
WH2_k127_6091100_5 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 331.0
WH2_k127_6091100_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000001433 202.0
WH2_k127_6091100_7 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000003704 135.0
WH2_k127_6091100_8 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000007511 89.0
WH2_k127_6224163_0 molybdopterin biosynthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000003814 171.0
WH2_k127_6224163_1 Protein of unknown function (DUF3016) - - - 0.000000000000000000000000000000007169 134.0
WH2_k127_6224163_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000002972 118.0
WH2_k127_6224163_3 Cell Wall Hydrolase - - - 0.0000000000000000000001227 101.0
WH2_k127_6224989_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 486.0
WH2_k127_6224989_1 Lipoprotein releasing system transmembrane protein K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000001658 231.0
WH2_k127_6224989_2 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000000000000002324 128.0
WH2_k127_627160_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1400.0
WH2_k127_627160_1 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1206.0
WH2_k127_627160_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00632 - 2.3.1.16 1.071e-197 623.0
WH2_k127_627160_3 ferredoxin--nadp reductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 421.0
WH2_k127_627160_4 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000002196 236.0
WH2_k127_627160_5 Cold-shock protein K03704 - - 0.00000000000000000000000000000000000761 137.0
WH2_k127_627160_6 Transcriptional regulator - - - 0.000000000000000000001225 94.0
WH2_k127_6300972_0 acyl-CoA dehydrogenase - - - 1.293e-225 702.0
WH2_k127_6300972_1 ArsR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 356.0
WH2_k127_6352860_0 Polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 369.0
WH2_k127_6352860_1 regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 361.0
WH2_k127_6352860_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 351.0
WH2_k127_6352860_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000003047 147.0
WH2_k127_6361476_0 Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) K00209 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.44,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 593.0
WH2_k127_6361476_1 LuxR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 316.0
WH2_k127_6361476_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 305.0
WH2_k127_6361476_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000002948 209.0
WH2_k127_6361476_4 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000006113 136.0
WH2_k127_6366467_0 Dak2 K07030 - - 5.723e-237 745.0
WH2_k127_6366467_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000114 219.0
WH2_k127_6366995_0 Alpha amylase, catalytic domain - - - 2.594e-289 899.0
WH2_k127_6366995_1 MOSC domain - - - 0.000000000000000000000000000000000000000000001596 168.0
WH2_k127_6366995_2 - - - - 0.00000000000000000000000000000006008 128.0
WH2_k127_6366995_3 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.00000004278 58.0
WH2_k127_6366995_4 Beta-lactamase - - - 0.0005136 48.0
WH2_k127_6377705_0 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 537.0
WH2_k127_6377705_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000002452 188.0
WH2_k127_647440_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 526.0
WH2_k127_647440_1 Stealth protein CR1, conserved region 1 - - - 0.00000000000000000000000000000000000000000000000000000000000004201 226.0
WH2_k127_647440_2 Sulfotransferase family - - - 0.0000000000000000000000003769 114.0
WH2_k127_647440_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000001246 53.0
WH2_k127_6476468_0 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase K03392 - 4.1.1.45 4.628e-199 622.0
WH2_k127_6476468_1 Belongs to the aldehyde dehydrogenase family K00130,K00151,K10217 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0008802,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 572.0
WH2_k127_6476468_2 Na+-dependent bicarbonate transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 422.0
WH2_k127_6476468_3 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 308.0
WH2_k127_6476468_4 Belongs to the aldehyde dehydrogenase family K00130,K00151,K10217 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0008802,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 305.0
WH2_k127_6476468_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000001865 247.0
WH2_k127_6476468_6 translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.0000000000000000000000000000000000000000000000000000000002294 206.0
WH2_k127_6498627_0 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 3.149e-200 638.0
WH2_k127_6498627_1 protein conserved in bacteria K09806 - - 0.00000000000000000000000000006592 119.0
WH2_k127_6498627_2 Rhodanese Homology Domain - - - 0.0009538 45.0
WH2_k127_6525134_0 MFS transporter K11381 - 1.2.4.4 0.0 1331.0
WH2_k127_6525134_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 313.0
WH2_k127_6525134_2 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000001246 189.0
WH2_k127_6525134_3 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000183 195.0
WH2_k127_6527676_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 596.0
WH2_k127_6527676_1 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 423.0
WH2_k127_6548487_0 chemotaxis protein K02660 - - 2.005e-209 670.0
WH2_k127_6548487_1 chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000000000000000000000000000000000000000009354 220.0
WH2_k127_6548487_2 response regulator K02657 - - 0.00000000000000000000000000000000000000000000000000000000000001241 216.0
WH2_k127_6548487_3 Histidine Phosphotransfer domain - - - 0.00000000000000000000003578 101.0
WH2_k127_6548487_4 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.00000000001106 66.0
WH2_k127_6558970_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 3.425e-300 928.0
WH2_k127_6558970_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 473.0
WH2_k127_6558970_2 TIGRFAM branched-chain amino acid aminotransferase, group II K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 442.0
WH2_k127_6558970_3 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 417.0
WH2_k127_6558970_4 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000004447 230.0
WH2_k127_6558970_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000004523 176.0
WH2_k127_656494_0 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 496.0
WH2_k127_656494_1 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 326.0
WH2_k127_656494_2 S1/P1 Nuclease - - - 0.000000000000000000000000000000000001186 145.0
WH2_k127_6609859_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 302.0
WH2_k127_6609859_1 Nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005003 244.0
WH2_k127_6609859_2 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000000003518 193.0
WH2_k127_6620785_0 BlaR1 peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007786 249.0
WH2_k127_6620785_1 Lipocalin-like domain K03098 GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000001192 199.0
WH2_k127_6620785_2 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000000166 166.0
WH2_k127_6620785_3 Lysine methyltransferase - - - 0.0000000005444 63.0
WH2_k127_6628202_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 7.668e-214 673.0
WH2_k127_6628202_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000147 271.0
WH2_k127_6628202_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000111 55.0
WH2_k127_6650470_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1402.0
WH2_k127_6650470_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 583.0
WH2_k127_6650470_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 489.0
WH2_k127_6650470_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 419.0
WH2_k127_6650470_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 338.0
WH2_k127_6650470_5 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 336.0
WH2_k127_6650470_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000006695 161.0
WH2_k127_6650470_7 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000001036 78.0
WH2_k127_6650470_8 Protein of unknown function (DUF721) - - - 0.0000000000001371 79.0
WH2_k127_6657616_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.883e-258 803.0
WH2_k127_6657616_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 442.0
WH2_k127_6696888_0 Pathogenicity protein K09800 - - 1.189e-200 668.0
WH2_k127_6696888_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 470.0
WH2_k127_6696888_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 418.0
WH2_k127_6696888_3 protein conserved in bacteria containing a pentein-type domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 339.0
WH2_k127_6696888_4 two-component system sensor protein K07637 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001077 224.0
WH2_k127_6741135_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 9.844e-319 979.0
WH2_k127_6741135_1 hemolysin III K11068 - - 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
WH2_k127_6741135_2 MASE1 - - - 0.000000000000000000000000000000000000000002888 156.0
WH2_k127_6741135_3 Peptidase family M23 - - - 0.00000000000000000000000000000000000008414 151.0
WH2_k127_6881308_0 Acyltransferase - - - 1.46e-286 891.0
WH2_k127_6881308_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006119 265.0
WH2_k127_6927697_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 496.0
WH2_k127_6927697_1 deiminase K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 483.0
WH2_k127_6927697_2 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000001558 214.0
WH2_k127_6984186_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 305.0
WH2_k127_6984186_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000007911 198.0
WH2_k127_7007798_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 545.0
WH2_k127_7007798_1 membrane K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 445.0
WH2_k127_7007798_2 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000002124 246.0
WH2_k127_7007798_3 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000001444 205.0
WH2_k127_7007798_4 CSS motif domain associated with EAL - - - 0.0000000000000000000000000000000000000000000000000002056 201.0
WH2_k127_7009116_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.44e-305 942.0
WH2_k127_7009116_1 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 530.0
WH2_k127_7009116_2 Branched-chain amino acid aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 336.0
WH2_k127_7201624_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 586.0
WH2_k127_7201624_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 402.0
WH2_k127_7201624_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000002845 132.0
WH2_k127_7201624_3 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000000005146 86.0
WH2_k127_7201624_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000001181 85.0
WH2_k127_7202994_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 390.0
WH2_k127_7202994_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 359.0
WH2_k127_7202994_2 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 339.0
WH2_k127_7202994_3 UPF0056 membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 311.0
WH2_k127_7202994_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000002654 145.0
WH2_k127_7213299_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 8.664e-309 956.0
WH2_k127_7213299_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 397.0
WH2_k127_7213299_2 4Fe-4S dicluster domain K21308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 394.0
WH2_k127_7213299_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 379.0
WH2_k127_7213299_4 DMSO reductase anchor subunit (DmsC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000132 269.0
WH2_k127_7229980_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 583.0
WH2_k127_7229980_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000004871 199.0
WH2_k127_7229980_2 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000005932 179.0
WH2_k127_7229980_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000002876 167.0
WH2_k127_7229980_4 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000001677 87.0
WH2_k127_7397023_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 3.413e-197 618.0
WH2_k127_7397023_1 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 472.0
WH2_k127_7397023_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001489 276.0
WH2_k127_7397023_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
WH2_k127_7408945_0 Multidrug efflux pump K03327 GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 533.0
WH2_k127_7408945_1 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000639 282.0
WH2_k127_7408945_2 Protein of unknown function (DUF3667) - - - 0.000009161 49.0
WH2_k127_7443347_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 1.027e-231 723.0
WH2_k127_7443347_1 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 409.0
WH2_k127_7443347_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 399.0
WH2_k127_7443347_3 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001196 252.0
WH2_k127_7443347_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000006106 138.0
WH2_k127_7511770_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.47e-312 965.0
WH2_k127_7511770_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 528.0
WH2_k127_7511770_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000002269 201.0
WH2_k127_7574022_0 Domain of unknown function (DUF4139) - - - 8.335e-201 638.0
WH2_k127_7574022_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 321.0
WH2_k127_7574022_2 membrane K07148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001174 275.0
WH2_k127_757499_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 3.689e-311 978.0
WH2_k127_757499_1 In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004874 277.0
WH2_k127_757499_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000005468 243.0
WH2_k127_7608560_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 461.0
WH2_k127_7608560_1 Belongs to the Smg family K03747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000645 234.0
WH2_k127_7608560_2 DNA processing protein DprA K04096 - - 0.0000000000000000000000000000000001517 138.0
WH2_k127_7616530_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015673,GO:0015679,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0031224,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0071944,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1902601,GO:1990169 - 0.0 1217.0
WH2_k127_7616530_1 Iron permease K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 432.0
WH2_k127_7616530_2 Long alpha hairpin domain of cation efflux system protein, CusB K07798 - - 0.00000000000000000000000000000000000000000000000000000000000002042 233.0
WH2_k127_7616530_3 transcriptional - - - 0.0000000000000000000000000000000000000000000000000006274 186.0
WH2_k127_7616530_4 MerT mercuric transport protein K08363 - - 0.0000000000000000000000000000000000000000000000007649 176.0
WH2_k127_7616530_5 MerR family transcriptional regulator K08365 - - 0.0000000000000000000000000000000000000006979 152.0
WH2_k127_7616530_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000003532 128.0
WH2_k127_7616530_7 Heavy-metal-associated domain K08364 - - 0.0000000000000000000000009184 107.0
WH2_k127_7616530_8 outer membrane efflux protein - - - 0.0000000000000000001192 103.0
WH2_k127_7616530_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000001573 57.0
WH2_k127_7666966_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 554.0
WH2_k127_7666966_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 433.0
WH2_k127_7666966_2 polyphosphate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 359.0
WH2_k127_7666966_3 UPF0761 membrane protein K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 366.0
WH2_k127_7666966_4 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002586 274.0
WH2_k127_7666966_5 asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007041 268.0
WH2_k127_7666966_6 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000009125 251.0
WH2_k127_7666966_7 FeS assembly SUF system protein SufT - - - 0.00000000000000000000000000000000000000000000000000000000000000002622 225.0
WH2_k127_7666966_8 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000006658 186.0
WH2_k127_7666966_9 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000001024 104.0
WH2_k127_767570_0 Aldose 1-epimerase K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000608 217.0
WH2_k127_767570_1 Histidine kinase - - - 0.00000000001101 72.0
WH2_k127_7680875_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 314.0
WH2_k127_7680875_1 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 308.0
WH2_k127_7680875_2 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001055 241.0
WH2_k127_7680875_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000002375 202.0
WH2_k127_7680875_4 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.0000000000000000000000000000000007155 134.0
WH2_k127_7689651_0 Rod shape-determining protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 580.0
WH2_k127_7689651_1 Sugar kinase K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 541.0
WH2_k127_7689651_2 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000007243 182.0
WH2_k127_7689651_3 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.00000000000000000000000000000000003216 139.0
WH2_k127_7689651_4 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000000000000000002127 127.0
WH2_k127_7716650_0 FAD-dependent dehydrogenases K07137 - - 3.42e-246 764.0
WH2_k127_7716650_1 Domain of unknown function (DUF5117) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 569.0
WH2_k127_7727423_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 343.0
WH2_k127_7727423_1 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 329.0
WH2_k127_7785257_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.72e-301 927.0
WH2_k127_7785257_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.736e-285 878.0
WH2_k127_7785257_10 ATP synthase subunit C - - - 0.0000000000000000000000000000000000000001114 152.0
WH2_k127_7785257_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 1.369e-202 639.0
WH2_k127_7785257_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 3.461e-197 620.0
WH2_k127_7785257_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 492.0
WH2_k127_7785257_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 355.0
WH2_k127_7785257_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 320.0
WH2_k127_7785257_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000302 214.0
WH2_k127_7785257_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000000005394 205.0
WH2_k127_7785257_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000005234 194.0
WH2_k127_7846198_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 3.696e-276 863.0
WH2_k127_7846198_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 595.0
WH2_k127_7846198_2 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 531.0
WH2_k127_7846198_3 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 376.0
WH2_k127_7846198_4 Putative sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 346.0
WH2_k127_7846198_5 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000125 252.0
WH2_k127_7846198_6 PadR family transcriptional regulator K10947 - - 0.00000000000000000000000000000000000000000000007693 171.0
WH2_k127_7846198_7 Uncharacterised protein family (UPF0093) - - - 0.0000000000000000000000000000000000000001368 154.0
WH2_k127_7846198_8 MAPEG family - - - 0.00000000000000000000000000000000000003361 147.0
WH2_k127_7874883_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 428.0
WH2_k127_7874883_1 Rhodopirellula transposase DDE domain - - - 0.000000000000000000000000000000000000000000834 161.0
WH2_k127_7918499_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 373.0
WH2_k127_7918499_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 359.0
WH2_k127_7918499_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 355.0
WH2_k127_7918499_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000001429 197.0
WH2_k127_7918499_4 Preprotein translocase subunit SecG K03075 - - 0.00000000000000000000000000003504 124.0
WH2_k127_7941890_0 heptosyltransferase K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 463.0
WH2_k127_7941890_1 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 350.0
WH2_k127_7941890_2 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000000000000000000000002467 205.0
WH2_k127_7941890_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000297 197.0
WH2_k127_7941890_4 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.000000000000000000000000000000000000000000000002574 183.0
WH2_k127_7995237_0 NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate K00031 - 1.1.1.42 1.266e-206 650.0
WH2_k127_7995237_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 377.0
WH2_k127_7995237_2 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000002512 125.0
WH2_k127_8037381_0 Efflux pump membrane transporter K19585 - - 7.176e-208 657.0
WH2_k127_8037381_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 424.0
WH2_k127_8037381_2 Predicted membrane protein (DUF2306) - - - 0.00000000000000000000001347 104.0
WH2_k127_8109851_0 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000004056 184.0
WH2_k127_8109851_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001438 153.0
WH2_k127_8109851_2 desaturase K00508 - 1.14.19.3 0.00000000000000000000000000000003225 126.0
WH2_k127_8109851_3 - - - - 0.0000000000000000000000008001 111.0
WH2_k127_8121949_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 2.319e-222 701.0
WH2_k127_8121949_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 350.0
WH2_k127_8121949_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 321.0
WH2_k127_8121949_3 cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 295.0
WH2_k127_8121949_4 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003762 263.0
WH2_k127_8121949_5 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000004188 218.0
WH2_k127_8121949_6 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000961 182.0
WH2_k127_8126334_0 ABC transporter K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 447.0
WH2_k127_8126334_1 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 366.0
WH2_k127_8139417_0 Major facilitator superfamily K03762 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 517.0
WH2_k127_8139417_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009851 389.0
WH2_k127_8139417_2 Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000322 287.0
WH2_k127_8139417_3 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000002473 182.0
WH2_k127_8139417_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000004573 159.0
WH2_k127_8139417_5 Pathogenicity locus - - - 0.0000000000000000000000000000005502 124.0
WH2_k127_8139417_6 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000303 96.0
WH2_k127_8139417_7 DUF167 K09131 - - 0.000000000000000005171 85.0
WH2_k127_8143434_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 5.772e-293 915.0
WH2_k127_8143434_1 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 470.0
WH2_k127_8143434_2 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 317.0
WH2_k127_8143434_3 acetyltransferase K06977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000343 260.0
WH2_k127_8143434_4 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 261.0
WH2_k127_8143434_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000002242 221.0
WH2_k127_8143434_6 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.0000000000000001051 82.0
WH2_k127_8143434_7 Histidine kinase - - - 0.000000000000007473 80.0
WH2_k127_815072_0 Phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 473.0
WH2_k127_815072_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 437.0
WH2_k127_815072_2 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 325.0
WH2_k127_8154762_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 400.0
WH2_k127_8154762_1 receptor K16090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 389.0
WH2_k127_8194389_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 3.901e-210 662.0
WH2_k127_8194389_1 - - - - 0.00000000000000000000000000000000000000000001302 171.0
WH2_k127_8194389_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000009584 138.0
WH2_k127_820049_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 451.0
WH2_k127_820049_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 447.0
WH2_k127_820049_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 404.0
WH2_k127_820049_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 385.0
WH2_k127_820049_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000001024 210.0
WH2_k127_820049_5 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000002136 178.0
WH2_k127_8202750_0 Acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 529.0
WH2_k127_8202750_1 trab family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 323.0
WH2_k127_8202750_2 Belongs to the agmatine deiminase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000619 253.0
WH2_k127_8238216_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 564.0
WH2_k127_8238216_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003075 271.0
WH2_k127_8238216_2 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000007593 222.0
WH2_k127_8238216_3 High frequency lysogenization protein HflD homolog K07153 - - 0.0000000000000000000000000000000000000000000000000000000000004282 217.0
WH2_k127_8238216_4 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease K03694 - - 0.000000000000000000000000000000000000000000000001034 175.0
WH2_k127_8238216_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000008612 147.0
WH2_k127_8238216_6 TonB dependent receptor K02014 - - 0.00000000000000000004027 90.0
WH2_k127_824835_0 3-hydroxyacyl-coa dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 8.091e-311 964.0
WH2_k127_824835_1 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 411.0
WH2_k127_824835_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 316.0
WH2_k127_824835_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003324 273.0
WH2_k127_824835_4 MucB/RseB C-terminal domain - - - 0.00000000000000000000000000000000000000000003126 172.0
WH2_k127_824835_5 Anti sigma-E protein RseA, N-terminal domain - - - 0.00000000000000289 85.0
WH2_k127_8276996_0 Potassium transporter TrkA - - - 6.167e-220 693.0
WH2_k127_8276996_1 fumarylacetoacetate hydrolase K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000002407 170.0
WH2_k127_8276996_2 ferredoxin - - - 0.00000000000000000000000004121 113.0
WH2_k127_8276996_3 - - - - 0.000001355 54.0
WH2_k127_8283315_0 C-terminus of AA_permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 551.0
WH2_k127_8283315_1 protein conserved in bacteria K09760 GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 307.0
WH2_k127_8283315_2 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000000000002155 251.0
WH2_k127_8283315_3 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.0000000000000000000000000000000000000000000000000000000000000000001139 235.0
WH2_k127_8283315_4 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 0.000000000000000000000000000000000000000000000000003254 186.0
WH2_k127_8283315_5 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.00000000000000000000000007932 111.0
WH2_k127_8400785_0 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 374.0
WH2_k127_8400785_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 352.0
WH2_k127_8400785_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000001064 211.0
WH2_k127_8413185_0 N-acyl-L-amino acid amidohydrolase K01436 - - 1.021e-202 638.0
WH2_k127_8413185_1 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 402.0
WH2_k127_8413185_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 333.0
WH2_k127_8413185_3 Alpha beta K07018 - - 0.0000000000000000000000000000000000000000000000000004794 188.0
WH2_k127_8413185_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000001608 101.0
WH2_k127_8418965_0 Bacterial protein of unknown function (DUF885) - - - 9.908e-238 748.0
WH2_k127_8418965_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 514.0
WH2_k127_8418965_2 SufE protein probably involved in Fe-S center assembly K02426 - - 0.000000000000000000000000000000000000000000000000000001098 195.0
WH2_k127_8447248_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.27e-286 885.0
WH2_k127_8447248_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 533.0
WH2_k127_8447248_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 457.0
WH2_k127_8447248_3 Restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000001574 158.0
WH2_k127_8447248_4 EamA-like transporter family - - - 0.00000000000004535 75.0
WH2_k127_848485_0 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 1.758e-218 688.0
WH2_k127_848485_1 COG2217 Cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 614.0
WH2_k127_848485_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 531.0
WH2_k127_848485_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 367.0
WH2_k127_848485_4 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 339.0
WH2_k127_848485_5 - - - - 0.000000000000000000000000000000000000001978 148.0
WH2_k127_848485_6 FixH K09926 - - 0.00000001649 63.0
WH2_k127_848485_7 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.00006046 46.0
WH2_k127_8523017_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 575.0
WH2_k127_8523017_1 Sodium ABC transporter permease K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 511.0
WH2_k127_8523017_2 abc transporter atp-binding protein K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 407.0
WH2_k127_8523017_3 Forkhead associated domain - - - 0.000000000000000000000000000004024 138.0
WH2_k127_8523017_4 - - - - 0.000000000000000000000000001709 117.0
WH2_k127_8523017_5 Helix-turn-helix domain K07729 - - 0.0000000000000000001294 91.0
WH2_k127_8523017_6 - - - - 0.000000003505 64.0
WH2_k127_8554948_0 Ferrous iron transport protein B K04759 - - 2.413e-243 764.0
WH2_k127_8554948_1 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008383 249.0
WH2_k127_8554948_2 enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000004138 208.0
WH2_k127_8554948_3 Thioredoxin - - - 0.000000000000000000000000000000000000000007998 158.0
WH2_k127_8554948_4 Fe2 transport system protein A K04758 - - 0.0000000000000000004237 91.0
WH2_k127_8559468_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1717.0
WH2_k127_8559468_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1028.0
WH2_k127_8559468_2 Protein of unknown function (DUF1298) - - - 1.036e-205 651.0
WH2_k127_8559468_3 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 514.0
WH2_k127_8559468_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 442.0
WH2_k127_8559468_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 432.0
WH2_k127_8559468_6 cytochrome c oxidase assembly protein K02258 - - 0.00000000000000000000000000000000000000000000000000000000000004052 219.0
WH2_k127_8559468_7 SURF1-like protein - - - 0.0000000000000000000000000000000000000000000000000002236 193.0
WH2_k127_8559468_8 signal sequence binding - - - 0.000000000000000000000000000000000000008339 149.0
WH2_k127_8559468_9 Protein of unknown function (DUF2909) - - - 0.0000000000000000000000008199 108.0
WH2_k127_8701349_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18303 - - 1.079e-262 818.0
WH2_k127_8701349_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18302 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 293.0
WH2_k127_8701349_2 AefR-like transcriptional repressor, C-terminal region - - - 0.00000000000000000000000000000002458 130.0
WH2_k127_8725342_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 6.638e-252 805.0
WH2_k127_8725342_1 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 326.0
WH2_k127_8725342_2 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000587 280.0
WH2_k127_8725342_3 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002601 278.0
WH2_k127_8725342_4 protein conserved in bacteria - - - 0.00000000000002867 76.0
WH2_k127_8725342_5 Acts as a magnesium transporter K06213 - - 0.0003718 44.0
WH2_k127_8737075_0 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003159 262.0
WH2_k127_8737075_1 Protein of unknown function (DUF3465) - - - 0.0000000000000000000000000000000000000000003155 163.0
WH2_k127_8737075_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000008557 155.0
WH2_k127_8737075_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0000000000000000000000000000000000002838 146.0
WH2_k127_8744240_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.663e-224 712.0
WH2_k127_8744240_1 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 461.0
WH2_k127_8744240_2 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 345.0
WH2_k127_878534_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 527.0
WH2_k127_878534_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 405.0
WH2_k127_878534_2 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 406.0
WH2_k127_878534_3 ATPase or kinase K06925 - - 0.00000000000000000000000000000000000009987 148.0
WH2_k127_8883019_0 TldD protein K03568 - - 1.093e-280 870.0
WH2_k127_8883019_1 Putative modulator of DNA gyrase - - - 5.076e-224 700.0
WH2_k127_8883019_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 497.0
WH2_k127_8883019_3 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 397.0
WH2_k127_8883019_4 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 369.0
WH2_k127_8883019_5 TldD protein K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 346.0
WH2_k127_8883019_6 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000001142 141.0
WH2_k127_8884790_0 Histidine ammonia-lyase K01745 - 4.3.1.3 7.613e-309 955.0
WH2_k127_8884790_1 calcineurin phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 556.0
WH2_k127_8884790_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000297 261.0
WH2_k127_8884790_3 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 0.00000000000000000000000000000000000000000000000000006031 189.0
WH2_k127_8907942_0 Peptidase M16 - - - 0.0 1195.0
WH2_k127_8907942_1 Peptide synthase K22319 - 6.1.3.1 1.458e-212 676.0
WH2_k127_8907942_2 synthase K22317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 575.0
WH2_k127_8907942_3 Alpha beta K22318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 422.0
WH2_k127_8907942_4 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000006338 173.0
WH2_k127_8907942_5 3-beta hydroxysteroid dehydrogenase K22320 - 1.1.1.412 0.000000000000000000000000000000000005038 139.0
WH2_k127_8907942_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000001714 142.0
WH2_k127_8907942_7 - - - - 0.0000001254 61.0
WH2_k127_8912634_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 515.0
WH2_k127_8912634_1 Protein of unknown function (DUF2785) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002747 273.0
WH2_k127_8915283_0 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle K01638 - 2.3.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 589.0
WH2_k127_8915283_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 490.0
WH2_k127_8915283_2 Catalyzes the reversible formation of glyoxylate and succinate from isocitrate K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009469 404.0
WH2_k127_8915283_3 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 293.0
WH2_k127_8980761_0 haloacid dehalogenase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 304.0
WH2_k127_8980761_1 desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 292.0
WH2_k127_8980761_2 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002107 283.0
WH2_k127_8980761_3 transcriptional regulator K22105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003035 277.0
WH2_k127_8980761_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000006055 241.0
WH2_k127_8980761_5 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000006264 234.0
WH2_k127_8980761_6 membrane K07278 - - 0.00000000000000000000000000000000000004977 151.0
WH2_k127_8980761_7 Transcriptional regulator sugar kinase K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000001144 77.0
WH2_k127_8983017_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 576.0
WH2_k127_8983017_1 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000007103 211.0
WH2_k127_8983017_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.00000000000001168 78.0
WH2_k127_8983017_3 Alpha beta K07018 - - 0.0000000001112 64.0
WH2_k127_8995564_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K04090 - 1.2.7.8 0.0 1585.0
WH2_k127_8995564_1 SBF-like CPA transporter family (DUF4137) K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 308.0
WH2_k127_8995564_2 Predicted membrane protein (DUF2238) K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 286.0
WH2_k127_8995564_3 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000436 278.0
WH2_k127_8995564_4 - - - - 0.0000000000000000000000000000000000000000000000000000005704 198.0
WH2_k127_8995564_5 endonuclease containing a URI domain K07461 - - 0.000000000000000000001022 97.0
WH2_k127_8995564_6 2OG-Fe(II) oxygenase superfamily - - - 0.00000000003832 69.0
WH2_k127_9014933_0 Transporter K03305 - - 1.109e-254 793.0
WH2_k127_9014933_1 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 451.0
WH2_k127_9014933_2 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 386.0
WH2_k127_9014933_3 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000007124 237.0
WH2_k127_9014933_4 peptidase - - - 0.00000000000000000000000000000000000000000000000000000003908 199.0
WH2_k127_902855_0 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 3.104e-214 677.0
WH2_k127_902855_1 Oxidoreductase K09471 - - 9.89e-205 648.0
WH2_k127_902855_2 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 559.0
WH2_k127_902855_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 421.0
WH2_k127_902855_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002087 271.0
WH2_k127_9093386_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.023e-228 713.0
WH2_k127_9093386_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 302.0
WH2_k127_9093386_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001764 268.0
WH2_k127_9093386_3 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000009227 244.0
WH2_k127_9093386_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001143 220.0
WH2_k127_9093386_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001168 213.0
WH2_k127_9093386_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000006071 194.0
WH2_k127_9093386_7 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000007535 113.0
WH2_k127_9121427_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 1.51e-298 927.0
WH2_k127_9121427_1 Sulfate adenylyltransferase subunit 2 K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 511.0
WH2_k127_9121427_2 ABC transporter transmembrane region K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 302.0
WH2_k127_9121427_3 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000005406 147.0
WH2_k127_9121427_4 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000001797 85.0
WH2_k127_9121427_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000176 44.0
WH2_k127_915685_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 1.544e-204 640.0
WH2_k127_915685_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 315.0
WH2_k127_915685_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 311.0
WH2_k127_915685_3 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000004884 92.0
WH2_k127_915685_4 - - - - 0.00007066 46.0
WH2_k127_9180150_0 TrkA-N domain - - - 3.466e-213 670.0
WH2_k127_9180150_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 3.638e-200 638.0
WH2_k127_9180150_2 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 355.0
WH2_k127_9210222_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 533.0
WH2_k127_9210222_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 318.0
WH2_k127_9210222_2 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 313.0
WH2_k127_9210222_3 EVE domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000007943 230.0
WH2_k127_9210222_4 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001195 222.0
WH2_k127_9210222_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000001155 211.0
WH2_k127_9210222_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001706 123.0
WH2_k127_9210222_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000001152 111.0
WH2_k127_9210222_8 TIGRFAM TIGR02449 family protein K09892 - - 0.00001442 49.0
WH2_k127_9223081_0 Biopolymer transporter ExbB K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 353.0
WH2_k127_9223081_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000000001242 223.0
WH2_k127_9223081_2 Biopolymer K03559 - - 0.00000000000000000000000000000000000000000000000007491 180.0
WH2_k127_9223081_3 Biopolymer K03559 - - 0.00000000000000000000000000000000000000000000001173 174.0
WH2_k127_9223081_4 Lecithin:cholesterol acyltransferase - - - 0.00000000000000000000000000000000000000000000002201 176.0
WH2_k127_9223081_5 COG0457 FOG TPR repeat - - - 0.0000000000000000000008271 99.0
WH2_k127_9227584_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 6.079e-220 698.0
WH2_k127_9227584_1 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 318.0
WH2_k127_9227584_2 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 317.0
WH2_k127_9227584_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000008241 188.0
WH2_k127_9227584_4 Bacterial PH domain K08981 - - 0.0000000000000000000000000000000000000000000000005196 182.0
WH2_k127_9227584_5 Bacterial PH domain K09167 - - 0.00000000000000000000000000000000002344 141.0
WH2_k127_9227584_6 Histidine kinase K08082 - 2.7.13.3 0.0000000004574 61.0
WH2_k127_9265400_0 Belongs to the inositol monophosphatase superfamily K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 396.0
WH2_k127_9265400_1 Hemolysins and related proteins containing CBS domains K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 391.0
WH2_k127_9265400_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 292.0
WH2_k127_9265400_3 exopolysaccharide synthesis - - - 0.0000000000000000000000000000000000000000000000000000002776 199.0
WH2_k127_9269720_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 587.0
WH2_k127_9269720_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 359.0
WH2_k127_9269720_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000002037 66.0
WH2_k127_9269720_3 - - - - 0.000000001405 61.0
WH2_k127_9273130_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1098.0
WH2_k127_9273130_1 Peptidase family S51 K13282 - 3.4.15.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003065 276.0
WH2_k127_9286588_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 392.0
WH2_k127_9286588_1 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 334.0
WH2_k127_9286588_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000007851 213.0
WH2_k127_9286588_3 dna polymerase III K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000001277 168.0
WH2_k127_9303488_0 Helicase K03578 - 3.6.4.13 3.402e-243 764.0
WH2_k127_9320026_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 533.0
WH2_k127_9320026_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 329.0
WH2_k127_9320026_2 carbonic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004289 238.0
WH2_k127_9320026_3 Protein of unknown function (DUF952) - - - 0.000008518 54.0
WH2_k127_9326592_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.066e-231 721.0
WH2_k127_9326592_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 289.0
WH2_k127_9326592_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000002841 149.0
WH2_k127_9326592_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000327 99.0
WH2_k127_9379106_0 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 2.612e-300 929.0
WH2_k127_9379106_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.145e-252 786.0
WH2_k127_9379106_10 Cell division protein - - - 0.00000000000000000000000001553 118.0
WH2_k127_9379106_2 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 1.609e-233 746.0
WH2_k127_9379106_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 480.0
WH2_k127_9379106_4 DNA-(Apurinic or apyrimidinic site) lyase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 416.0
WH2_k127_9379106_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 334.0
WH2_k127_9379106_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 295.0
WH2_k127_9379106_7 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000005088 239.0
WH2_k127_9379106_8 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000001167 183.0
WH2_k127_9379106_9 - - - - 0.0000000000000000000000000000000004981 141.0
WH2_k127_9417694_0 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
WH2_k127_9417694_1 Rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000003397 196.0
WH2_k127_9417694_2 HemX, putative uroporphyrinogen-III C-methyltransferase K02496 - 2.1.1.107 0.0000000000000000000000000000000000004447 149.0
WH2_k127_9417694_3 - - - - 0.0000000000000000000000000005079 119.0
WH2_k127_9417694_4 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.000000000000000000000000001245 123.0
WH2_k127_9419675_0 membrane protein terc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 323.0
WH2_k127_9419675_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 307.0
WH2_k127_9419675_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009579 296.0
WH2_k127_9419675_3 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000002631 222.0
WH2_k127_9419675_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000002146 203.0
WH2_k127_9435398_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.512e-230 718.0
WH2_k127_9435398_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 421.0
WH2_k127_9435398_2 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 380.0
WH2_k127_9435398_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 350.0
WH2_k127_9435398_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000001853 143.0
WH2_k127_9435398_5 component I K01657 - 4.1.3.27 0.0000000000000326 74.0
WH2_k127_9439159_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.534e-308 963.0
WH2_k127_9439159_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 564.0
WH2_k127_9439159_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003172 270.0
WH2_k127_9439159_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000007312 196.0
WH2_k127_9439159_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000001373 180.0
WH2_k127_9439159_5 transcriptional - - - 0.0000000000000000000000000000000000004065 143.0
WH2_k127_9439159_6 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000004376 127.0
WH2_k127_9461951_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 9.603e-299 929.0
WH2_k127_9461951_1 Belongs to the HSP15 family K04762 - - 0.0000000000000000000000000000000000000000003564 162.0
WH2_k127_9461951_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000004205 119.0
WH2_k127_9507429_0 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 455.0
WH2_k127_9507429_1 (Rhomboid) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008282 246.0
WH2_k127_9507429_2 membrane protein terc K05794 - - 0.00000000000000000000000000000000002203 136.0
WH2_k127_9534924_0 TraB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 290.0
WH2_k127_9534924_1 Divalent cation transporter - - - 0.000000000000000000000000000000000000000000000002062 182.0
WH2_k127_9534924_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000002853 67.0
WH2_k127_9542926_0 Lipoprotein releasing system transmembrane protein K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 367.0
WH2_k127_9542926_1 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 290.0
WH2_k127_9542926_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000008146 97.0
WH2_k127_9547065_0 Histidine Phosphotransfer domain - - - 7.581e-195 634.0
WH2_k127_9547065_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000004199 61.0
WH2_k127_9557658_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 585.0
WH2_k127_9557658_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 388.0
WH2_k127_9557658_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 359.0
WH2_k127_9557658_3 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003089 250.0
WH2_k127_9557658_4 CYTH domain protein K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000005069 223.0
WH2_k127_9557658_5 COG0784 FOG CheY-like receiver - - - 0.0000000000000000006446 95.0
WH2_k127_9557658_6 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000007114 70.0
WH2_k127_9557658_7 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000002101 55.0
WH2_k127_9586741_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 392.0
WH2_k127_9586741_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 287.0
WH2_k127_9586741_2 Alpha/beta hydrolase family - - - 0.000006107 49.0
WH2_k127_9604255_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0 1236.0
WH2_k127_9604255_1 - - - - 0.00000000000000000000000000000001189 138.0
WH2_k127_9604255_2 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0000000000000000000009367 96.0
WH2_k127_9604255_3 Protein of unknown function (DUF465) - - - 0.00000000005509 71.0
WH2_k127_9604255_4 May be involved in recombination K03554 - - 0.00000000008395 68.0
WH2_k127_9657484_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 394.0
WH2_k127_9657484_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 325.0
WH2_k127_9657484_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005065 249.0
WH2_k127_9657484_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000001034 218.0
WH2_k127_9657484_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000006758 182.0
WH2_k127_9657484_5 - - - - 0.0000000000000000000000000000000000000000004813 163.0
WH2_k127_9657484_6 TIGRFAM HipA N-terminal domain protein K07154 - 2.7.11.1 0.000000000000000000000000001194 115.0
WH2_k127_9657484_7 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000003467 103.0
WH2_k127_9709478_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1370.0
WH2_k127_9709478_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 602.0
WH2_k127_9709478_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000002876 167.0
WH2_k127_9709478_3 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000007635 153.0
WH2_k127_9709478_4 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000000000000002236 100.0
WH2_k127_9717657_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 5.524e-210 660.0
WH2_k127_9717657_1 nucleotidase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 297.0
WH2_k127_9717657_2 ADP-ribose diphosphatase K08312 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000546 267.0
WH2_k127_9717657_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000003659 259.0
WH2_k127_9717657_4 Two component signalling adaptor domain K06598 - - 0.0000000000000000000000000000000000001608 145.0
WH2_k127_9717657_5 protein-glutamate methylesterase K06597 - - 0.000000000000000001364 93.0
WH2_k127_9718577_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 387.0
WH2_k127_9718577_1 aminotransferase K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000001559 261.0
WH2_k127_9718577_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007062 252.0
WH2_k127_9718577_3 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000002798 239.0
WH2_k127_9723266_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 629.0
WH2_k127_983011_0 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 441.0
WH2_k127_983011_1 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001184 275.0
WH2_k127_983011_2 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000007895 130.0
WH2_k127_983011_3 Bacterial regulatory protein, Fis family K03557 - - 0.000000000000000000000006742 103.0
WH2_k127_983011_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000004209 100.0
WH2_k127_9979107_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1156.0
WH2_k127_9979107_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 586.0
WH2_k127_9979994_0 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA K06445 - - 1.995e-309 955.0
WH2_k127_9979994_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000625 265.0
WH2_k127_9979994_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000000000000000003774 89.0