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Overview

ID MAG04142
Name WH3_bin.24
Sample SMP0108
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanosarcinia
Order Methanotrichales
Family Methanotrichaceae
Genus Methanothrix
Species Methanothrix soehngenii
Assembly information
Completeness (%) 92.65
Contamination (%) 1.0
GC content (%) 53.0
N50 (bp) 9,287
Genome size (bp) 2,268,637

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2173

Gene name Description KEGG GOs EC E-value Score Sequence
WH3_k127_10022417_0 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 544.0
WH3_k127_10022417_1 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 486.0
WH3_k127_10022417_2 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 399.0
WH3_k127_10022417_3 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000001187 162.0
WH3_k127_10022417_4 Integral membrane protein DUF106 - - - 0.0000001536 53.0
WH3_k127_10024716_0 pentaerythritol trinitrate reductase activity - - - 3.378e-283 882.0
WH3_k127_10024716_1 acetoacetate decarboxylase activity K01574 - 4.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 368.0
WH3_k127_10024716_10 Flavin reductase like domain - - - 0.0000168 47.0
WH3_k127_10024716_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 357.0
WH3_k127_10024716_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 297.0
WH3_k127_10024716_4 - - - - 0.000000000000000000000000000000000000000000000000000000001813 203.0
WH3_k127_10024716_5 oligosaccharyl transferase STT3 subunit - - - 0.0000000000000000000000005103 114.0
WH3_k127_10024716_6 Flavin reductase like domain - - - 0.0000000000000000001363 88.0
WH3_k127_10024716_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000002031 69.0
WH3_k127_10024716_8 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000003647 79.0
WH3_k127_10024716_9 Flavin reductase like domain - - - 0.000000776 55.0
WH3_k127_10105623_0 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 373.0
WH3_k127_10105623_1 PFAM formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000002683 248.0
WH3_k127_10105623_2 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000002466 204.0
WH3_k127_10105623_3 Non-histone chromosomal protein MC1 - - - 0.0000000000000000000000003394 107.0
WH3_k127_10105623_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000001409 70.0
WH3_k127_10105623_5 Putative Fe-S cluster - - - 0.000000007512 61.0
WH3_k127_10184787_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 533.0
WH3_k127_10184787_1 PFAM CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 463.0
WH3_k127_10184787_2 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 408.0
WH3_k127_10184787_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000411 261.0
WH3_k127_10184787_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000001698 179.0
WH3_k127_10184787_5 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000002914 90.0
WH3_k127_10184787_6 - - - - 0.00000000003378 70.0
WH3_k127_10279936_0 transcriptional regulator - - - 1.536e-243 764.0
WH3_k127_10279936_1 - - - - 0.000000000000000000001665 98.0
WH3_k127_10279936_2 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000002137 75.0
WH3_k127_10310640_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 379.0
WH3_k127_10310640_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 345.0
WH3_k127_10310640_2 Universal stress protein family - - - 0.0000000005064 64.0
WH3_k127_10318203_0 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004904 288.0
WH3_k127_10395775_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 375.0
WH3_k127_10395775_1 PFAM Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000000000000007634 149.0
WH3_k127_10395775_2 Tetratricopeptide repeat - - - 0.00000000000000000000000007545 124.0
WH3_k127_10395775_3 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000004096 109.0
WH3_k127_10395775_4 - - - - 0.0000000002685 64.0
WH3_k127_10395775_5 - - - - 0.00000000158 66.0
WH3_k127_10395775_6 Protein of unknown function (DUF1328) - - - 0.000007924 51.0
WH3_k127_10396882_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 494.0
WH3_k127_10396882_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 379.0
WH3_k127_10396882_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 340.0
WH3_k127_10396882_3 Domain of unknown function (DUF1743) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 328.0
WH3_k127_10396882_4 pfam nmd3 K07562 - - 0.00000000000000000000000000000000000000003698 163.0
WH3_k127_10396882_5 hydrolase K04794 - 3.1.1.29 0.000000000000000000000000000000000003378 141.0
WH3_k127_10396882_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - 0.0000000000000000000000005813 108.0
WH3_k127_10396882_7 NB-ARC domain - - - 0.0002392 47.0
WH3_k127_10446184_0 ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues K01648 GO:0000166,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003878,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006084,GO:0006085,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009893,GO:0009987,GO:0012505,GO:0015936,GO:0016020,GO:0016053,GO:0016125,GO:0016126,GO:0016192,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0018130,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030141,GO:0030554,GO:0031323,GO:0031325,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032940,GO:0032991,GO:0033500,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0034774,GO:0035337,GO:0035383,GO:0035384,GO:0035578,GO:0035639,GO:0036094,GO:0036230,GO:0042119,GO:0042582,GO:0042592,GO:0042593,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046165,GO:0046390,GO:0046394,GO:0046483,GO:0046903,GO:0046912,GO:0046949,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0055086,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653,GO:1904813 2.3.3.8 5.925e-229 726.0
WH3_k127_10446184_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 559.0
WH3_k127_10446184_10 PFAM Protein kinase domain - - - 0.000000000000000000000000000002927 139.0
WH3_k127_10446184_11 - - - - 0.0000000000001589 76.0
WH3_k127_10446184_12 Tetratricopeptide repeat - - - 0.0000001263 65.0
WH3_k127_10446184_2 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 553.0
WH3_k127_10446184_3 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 511.0
WH3_k127_10446184_4 ATP citrate synthase activity K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 425.0
WH3_k127_10446184_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 292.0
WH3_k127_10446184_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000005514 230.0
WH3_k127_10446184_7 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000007175 182.0
WH3_k127_10446184_8 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000006775 166.0
WH3_k127_10446184_9 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000004157 159.0
WH3_k127_10478982_0 CobN/Magnesium Chelatase K02230 - 6.6.1.2 0.0 1407.0
WH3_k127_10478982_1 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 334.0
WH3_k127_10478982_2 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000008038 185.0
WH3_k127_10478982_3 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000317 143.0
WH3_k127_10478982_4 Domain of unknown function DUF11 - - - 0.0000000000000000002773 102.0
WH3_k127_10483880_0 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 3.61e-214 676.0
WH3_k127_10483880_1 Biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000007071 201.0
WH3_k127_10483880_2 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000002662 182.0
WH3_k127_10483880_3 Prokaryotic homologs of the JAB domain - - - 0.00000000000000000000000000000000000000000000001918 174.0
WH3_k127_10483880_4 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000006686 169.0
WH3_k127_10483880_5 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.00000000000000000000000000000000000000006275 156.0
WH3_k127_10483880_6 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000005695 84.0
WH3_k127_10499556_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 379.0
WH3_k127_10499556_1 Translation initiation factor 2 alpha subunit K03237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 309.0
WH3_k127_10499556_2 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 292.0
WH3_k127_10499556_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000001353 191.0
WH3_k127_10499556_4 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000001879 142.0
WH3_k127_10499556_5 PFAM Ribosomal protein S27E K02978 - - 0.0000000000000000003118 89.0
WH3_k127_10499556_6 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000001017 76.0
WH3_k127_10499556_7 protein conserved in archaea K09723 - - 0.00002938 53.0
WH3_k127_10507783_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 588.0
WH3_k127_10507783_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 553.0
WH3_k127_10507783_10 PFAM Glycosyl transferase, group 1 K12996 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000005568 220.0
WH3_k127_10507783_11 Glycosyl transferase 4-like - - - 0.00000001992 66.0
WH3_k127_10507783_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 465.0
WH3_k127_10507783_3 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 462.0
WH3_k127_10507783_4 Beta-eliminating lyase K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 444.0
WH3_k127_10507783_5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 395.0
WH3_k127_10507783_6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 372.0
WH3_k127_10507783_7 PFAM oxidoreductase domain protein K18855 - 1.1.1.374 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 328.0
WH3_k127_10507783_8 PFAM Bacterial transferase hexapeptide (three repeats) K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000749 263.0
WH3_k127_10507783_9 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009245 262.0
WH3_k127_10545323_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 396.0
WH3_k127_10545323_1 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 322.0
WH3_k127_10545323_2 Methyltransferase K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002595 283.0
WH3_k127_10545323_3 Domain of unknown function DUF11 - - - 0.000000000000000005528 99.0
WH3_k127_10545323_4 metallopeptidase activity - - - 0.0000000000001035 81.0
WH3_k127_10545323_5 Iron-sulphur cluster biosynthesis K15724 - - 0.000000000005243 72.0
WH3_k127_10545323_6 cellulase activity - - - 0.000224 54.0
WH3_k127_10576820_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1509.0
WH3_k127_10576820_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 340.0
WH3_k127_10576820_10 - - - - 0.0001496 44.0
WH3_k127_10576820_2 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000903 291.0
WH3_k127_10576820_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000001448 156.0
WH3_k127_10576820_4 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000000000003992 126.0
WH3_k127_10576820_5 Lrp/AsnC ligand binding domain - - - 0.00000000000000000009646 90.0
WH3_k127_10576820_6 Y_Y_Y domain - - - 0.0000000000000009862 93.0
WH3_k127_10576820_8 SMART Tetratricopeptide domain protein - - - 0.000000000002126 73.0
WH3_k127_10576820_9 metallopeptidase activity K01126,K01181 - 3.1.4.46,3.2.1.8 0.00009341 57.0
WH3_k127_10614330_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 431.0
WH3_k127_10614330_1 RimK domain protein ATP-grasp K05844,K15740 - 6.3.2.33 0.000000000000000000000000000000000000000000000000000000000000005079 228.0
WH3_k127_10614330_2 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000000000000008656 187.0
WH3_k127_10614330_3 nuclease - - - 0.0000000000000000000000000000000000000000001016 165.0
WH3_k127_10644742_0 ABC-type Fe3 -siderophore transport system, permease component K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 416.0
WH3_k127_10644742_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 308.0
WH3_k127_10644742_2 cobalt chelatase K02190 - 4.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000006241 233.0
WH3_k127_10644742_3 Probable transposase K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000161 222.0
WH3_k127_10644742_4 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000001276 100.0
WH3_k127_10644742_5 Homeodomain-like domain K06933 - - 0.0000000000000000000001574 103.0
WH3_k127_10644742_6 - - - - 0.00000000000006543 78.0
WH3_k127_10644742_7 Periplasmic binding protein K02016 - - 0.00000000003198 76.0
WH3_k127_10644742_8 Family of unknown function (DUF5320) - - - 0.0005953 46.0
WH3_k127_10801829_0 NB-ARC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 512.0
WH3_k127_10801829_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000002599 155.0
WH3_k127_10801829_2 PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - 0.0000000000000000000002508 100.0
WH3_k127_10801829_3 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ K04034 - 1.21.98.3 0.000000000000001962 83.0
WH3_k127_10801829_4 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000002508 77.0
WH3_k127_10801829_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000001487 64.0
WH3_k127_10801829_6 - - - - 0.0004125 51.0
WH3_k127_10801829_7 - - - - 0.0004135 46.0
WH3_k127_10811295_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 543.0
WH3_k127_10820335_0 Required for chromosome condensation and partitioning K03529 - - 6.015e-292 934.0
WH3_k127_10820335_1 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 567.0
WH3_k127_10820335_2 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 501.0
WH3_k127_10820335_3 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.0000000000000000000000000000000000001678 145.0
WH3_k127_10820335_4 Segregation and condensation protein ScpA K05896 - - 0.00000000000000000000000000000000000202 146.0
WH3_k127_10828234_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 403.0
WH3_k127_10828234_1 PFAM TM2 domain containing protein K03686 - - 0.000000000000000000001853 98.0
WH3_k127_10892254_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 362.0
WH3_k127_10892254_1 extracellular matrix structural constituent - - - 0.0000000122 66.0
WH3_k127_10902065_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 454.0
WH3_k127_10902065_1 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000000000000007095 221.0
WH3_k127_10902065_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000000000003662 221.0
WH3_k127_10902065_3 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000001513 174.0
WH3_k127_10902065_4 Na+/H+ ion antiporter subunit K05569 - - 0.0000000000000000000000000000000000000000005382 164.0
WH3_k127_10902065_5 - - - - 0.00000000000000000000000000000000000000007517 157.0
WH3_k127_10902065_6 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000000000005308 136.0
WH3_k127_10902065_7 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.00000000000000000000005643 100.0
WH3_k127_10919853_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 561.0
WH3_k127_10922196_0 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 312.0
WH3_k127_10922196_1 Probable transposase K07496 - - 0.0000000000000000000000000000000000000000000000000001919 199.0
WH3_k127_10926261_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1035.0
WH3_k127_10926261_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 625.0
WH3_k127_10926261_10 LUD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001524 240.0
WH3_k127_10926261_11 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000000000000000000000000000005189 229.0
WH3_k127_10926261_12 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K00441,K22174 - 1.1.98.4,1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000005633 227.0
WH3_k127_10926261_13 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000002734 203.0
WH3_k127_10926261_14 - - - - 0.00000000000000000000000000000000000000000000000000006343 201.0
WH3_k127_10926261_15 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000247 189.0
WH3_k127_10926261_16 PBP superfamily domain - - - 0.000000000000000000000000000000000000000000000008076 183.0
WH3_k127_10926261_17 Universal stress protein family - - - 0.000000000000000000000000007955 115.0
WH3_k127_10926261_18 response to pH - - - 0.00000000000000000000000002374 114.0
WH3_k127_10926261_19 Flavodoxin - - - 0.00000000000000000000000002867 114.0
WH3_k127_10926261_2 Erythromycin esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 540.0
WH3_k127_10926261_20 Winged helix-turn-helix - - - 0.0000000003455 64.0
WH3_k127_10926261_21 Acylphosphatase K01512 - 3.6.1.7 0.0000000004712 67.0
WH3_k127_10926261_22 Belongs to the acylphosphatase family - - - 0.00000008033 55.0
WH3_k127_10926261_3 TGS domain protein K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 496.0
WH3_k127_10926261_4 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 370.0
WH3_k127_10926261_5 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 359.0
WH3_k127_10926261_6 Probable transposase K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 315.0
WH3_k127_10926261_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 301.0
WH3_k127_10926261_8 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 293.0
WH3_k127_10926261_9 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005769 267.0
WH3_k127_10943673_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 381.0
WH3_k127_10943673_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 341.0
WH3_k127_10943673_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000002657 198.0
WH3_k127_10943673_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000000003819 195.0
WH3_k127_10943673_12 TIGRFAM ribosomal protein L30P K02907 - - 0.00000000000000000000000000000000000000000000000000318 186.0
WH3_k127_10943673_13 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000002008 170.0
WH3_k127_10943673_14 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000003913 168.0
WH3_k127_10943673_15 binds to the 23S rRNA K02885 - - 0.0000000000000000000000000000000000000000002302 163.0
WH3_k127_10943673_16 PFAM Ribosomal protein K02912 - - 0.000000000000000000000000000002352 123.0
WH3_k127_10943673_17 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.00000000000000000000000000001045 121.0
WH3_k127_10943673_18 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000000000000004725 98.0
WH3_k127_10943673_19 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.00000000000000000007601 89.0
WH3_k127_10943673_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 328.0
WH3_k127_10943673_20 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000000000000004483 87.0
WH3_k127_10943673_21 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000002114 77.0
WH3_k127_10943673_22 - - - - 0.0000001474 61.0
WH3_k127_10943673_23 binds to the 23S rRNA K02876 - - 0.0009684 46.0
WH3_k127_10943673_3 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 299.0
WH3_k127_10943673_4 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 292.0
WH3_k127_10943673_5 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001834 274.0
WH3_k127_10943673_6 Putative RNA methyltransferase K09142 - - 0.0000000000000000000000000000000000000000000000000000000000000000000281 242.0
WH3_k127_10943673_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000001338 217.0
WH3_k127_10943673_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000008471 209.0
WH3_k127_10943673_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000006621 209.0
WH3_k127_10954011_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002679 272.0
WH3_k127_10954011_1 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000001782 202.0
WH3_k127_10954011_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000222 186.0
WH3_k127_10954011_3 - - - - 0.0000000000000000000000000000000000000000000002905 172.0
WH3_k127_10954011_4 CAAX protease self-immunity - - - 0.0000000000000007761 78.0
WH3_k127_10954011_5 S-layer protein - - - 0.000000001986 68.0
WH3_k127_10960626_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 359.0
WH3_k127_10960626_1 methyltransferase K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 334.0
WH3_k127_10960626_2 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000003392 230.0
WH3_k127_10960626_3 PFAM regulatory protein, ArsR - - - 0.00000000000000000005268 93.0
WH3_k127_10960626_4 PFAM regulatory protein, ArsR - - - 0.000000000000007758 76.0
WH3_k127_10960626_5 Alternative locus ID K15383 - - 0.00000000000006698 75.0
WH3_k127_10960626_6 - - - - 0.0000000008333 64.0
WH3_k127_10970899_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 606.0
WH3_k127_10970899_1 Mn2 dependent serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 429.0
WH3_k127_10970899_2 RNA methylase K07446 - 2.1.1.213 0.00000000000000000000000000000000000000000000000000000000000000000000000000002481 270.0
WH3_k127_10970899_3 Winged helix-turn-helix - - - 0.00000001037 59.0
WH3_k127_10987076_0 Protein of unknown function (DUF1646) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 369.0
WH3_k127_10987076_1 SMART Elongator protein 3 MiaB NifB K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 310.0
WH3_k127_10987076_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000001478 214.0
WH3_k127_10987076_3 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000004072 185.0
WH3_k127_10987076_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000008293 156.0
WH3_k127_10987076_5 Protein of unknown function (DUF1646) - - - 0.00000000000000008021 90.0
WH3_k127_10987076_6 Putative transposase DNA-binding domain - - - 0.0000000002477 63.0
WH3_k127_11002436_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 552.0
WH3_k127_11002436_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 452.0
WH3_k127_11002436_10 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000007521 128.0
WH3_k127_11002436_11 low-complexity proteins - - - 0.0000000000000000002662 98.0
WH3_k127_11002436_12 Lrp/AsnC ligand binding domain - - - 0.000000000006809 69.0
WH3_k127_11002436_13 S-layer homology domain - - - 0.00000000003979 78.0
WH3_k127_11002436_14 extracellular matrix structural constituent - - - 0.0000000001909 75.0
WH3_k127_11002436_15 Copper amine oxidase N-terminal domain K13730,K13731 - - 0.0000000008216 73.0
WH3_k127_11002436_2 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 354.0
WH3_k127_11002436_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 357.0
WH3_k127_11002436_4 DHH family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000829 288.0
WH3_k127_11002436_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000186 205.0
WH3_k127_11002436_6 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000001877 196.0
WH3_k127_11002436_7 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000006794 154.0
WH3_k127_11002436_8 - - - - 0.00000000000000000000000000000000006157 138.0
WH3_k127_11002436_9 Domain of unknown function DUF123 - - - 0.00000000000000000000000000000002172 132.0
WH3_k127_11011258_0 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 316.0
WH3_k127_11011258_1 ABC transporter K06147,K11085 - - 0.000000000000002742 78.0
WH3_k127_11011258_2 COGs COG2274 ABC-type bacteriocin lantibiotic exporter contain an N-terminal double-glycine peptidase domain - - - 0.0000007482 53.0
WH3_k127_11016594_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.999e-227 720.0
WH3_k127_11016594_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000001241 71.0
WH3_k127_11017047_0 TIGRFAM Acetate-CoA ligase K01895 - 6.2.1.1 3.114e-252 795.0
WH3_k127_11017047_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.169e-249 785.0
WH3_k127_11017047_2 SMART Elongator protein 3 MiaB NifB K15865 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 322.0
WH3_k127_11017047_3 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000002955 229.0
WH3_k127_11017047_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000002448 137.0
WH3_k127_1102898_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1091.0
WH3_k127_1102898_1 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 5.163e-278 880.0
WH3_k127_1102898_10 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 282.0
WH3_k127_1102898_11 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000622 264.0
WH3_k127_1102898_12 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003627 265.0
WH3_k127_1102898_13 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006715 259.0
WH3_k127_1102898_14 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001127 257.0
WH3_k127_1102898_15 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000481 232.0
WH3_k127_1102898_16 Hit family K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000002338 222.0
WH3_k127_1102898_17 binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000009276 221.0
WH3_k127_1102898_18 RIO1 family K08851 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000001597 218.0
WH3_k127_1102898_19 Domain of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000002227 216.0
WH3_k127_1102898_2 in RNase L inhibitor, RLI K06174 - - 5.985e-242 760.0
WH3_k127_1102898_20 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000009394 210.0
WH3_k127_1102898_21 phosphoribosylglycinamide formyltransferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000001565 192.0
WH3_k127_1102898_22 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000469 184.0
WH3_k127_1102898_23 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000008757 182.0
WH3_k127_1102898_24 PFAM helix-turn-helix HxlR type - - - 0.000000000000000000000000000000000000000000000002106 176.0
WH3_k127_1102898_25 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.000000000000000000000000000000000000000001731 161.0
WH3_k127_1102898_26 - - - - 0.0000000000000000000000000000000000000003475 162.0
WH3_k127_1102898_27 signal transduction protein with CBS domains - - - 0.00000000000000000000000000000000000008247 149.0
WH3_k127_1102898_28 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000000003771 124.0
WH3_k127_1102898_29 Mut7-C RNAse domain - - - 0.0000000000000000000000000002706 117.0
WH3_k127_1102898_3 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 2.971e-210 660.0
WH3_k127_1102898_30 extracellular matrix structural constituent - - - 0.0000000000000000000000000003591 125.0
WH3_k127_1102898_31 PIN domain of ribonuclease K07060 - - 0.0000000000000000000000000003709 124.0
WH3_k127_1102898_32 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000004276 128.0
WH3_k127_1102898_33 InterPro IPR007367 - - - 0.000000000000000000000000005351 113.0
WH3_k127_1102898_34 RNase L inhibitor, RLI - - - 0.000000000000000003273 92.0
WH3_k127_1102898_35 - - - - 0.00000000003881 74.0
WH3_k127_1102898_4 LOR SDH bifunctional enzyme conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 502.0
WH3_k127_1102898_5 membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 406.0
WH3_k127_1102898_6 RNA ligase K07468 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 350.0
WH3_k127_1102898_7 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 295.0
WH3_k127_1102898_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 297.0
WH3_k127_1102898_9 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 292.0
WH3_k127_11056913_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 332.0
WH3_k127_11056913_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000003528 141.0
WH3_k127_11056913_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.00000000000000000000000001282 110.0
WH3_k127_11056913_3 PFAM Uncharacterised conserved protein UCP019262 - - - 0.00000000000000003435 89.0
WH3_k127_11069318_0 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002545 254.0
WH3_k127_11069318_1 ADP-specific Phosphofructokinase/Glucokinase conserved region K00918 - 2.7.1.146,2.7.1.147 0.00000000000000000000000000000000000000000004424 175.0
WH3_k127_11069318_2 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.0000000002409 65.0
WH3_k127_11069318_3 - - - - 0.00000001108 57.0
WH3_k127_11079400_0 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 376.0
WH3_k127_11079400_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000001853 250.0
WH3_k127_11079400_2 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000006848 167.0
WH3_k127_11079400_3 Belongs to the N(4) N(6)-methyltransferase family K07316 - 2.1.1.72 0.00002609 49.0
WH3_k127_11186496_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 286.0
WH3_k127_11186496_1 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000007623 212.0
WH3_k127_11186496_2 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000000003893 111.0
WH3_k127_11191631_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 3270.0
WH3_k127_11191631_1 AAA-4 family - - - 0.0 1045.0
WH3_k127_11191631_10 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000003128 114.0
WH3_k127_11191631_11 - - - - 0.0000000000000000005586 92.0
WH3_k127_11191631_12 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.000000000000000003286 84.0
WH3_k127_11191631_13 - - - - 0.000000000000000009446 85.0
WH3_k127_11191631_2 Protein of unknown function (DUF1016) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 473.0
WH3_k127_11191631_3 restriction modification system DNA specificity K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 439.0
WH3_k127_11191631_4 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000000000000000000000000005728 235.0
WH3_k127_11191631_5 Dihydrouridine synthase (Dus) - - - 0.000000000000000000000000000000000000000000000000000000000001599 223.0
WH3_k127_11191631_6 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000000009849 203.0
WH3_k127_11191631_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000002765 201.0
WH3_k127_11191631_8 Putative small multi-drug export protein - - - 0.0000000000000000000000000000000000000000000000005627 179.0
WH3_k127_11191631_9 Protein of unknown function (DUF447) K09154 - - 0.00000000000000000000000000000004728 134.0
WH3_k127_11191869_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 426.0
WH3_k127_11191869_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 394.0
WH3_k127_11191869_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000002379 200.0
WH3_k127_11191869_3 - - - - 0.000008418 55.0
WH3_k127_11192753_0 Winged helix-turn-helix domain (DUF2582) - - - 0.000001128 54.0
WH3_k127_11192753_1 Thioredoxin-like - - - 0.0005965 51.0
WH3_k127_11217356_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 311.0
WH3_k127_11217356_1 COG2897 Rhodanese-related sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000005954 110.0
WH3_k127_11290175_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 554.0
WH3_k127_11290175_1 S-layer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 423.0
WH3_k127_11290175_2 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 393.0
WH3_k127_11290175_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000001428 98.0
WH3_k127_11290175_4 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000002453 91.0
WH3_k127_11297026_0 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 337.0
WH3_k127_11297026_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000001182 181.0
WH3_k127_11297026_2 Winged helix-turn-helix - - - 0.000000623 55.0
WH3_k127_11297026_3 - - - - 0.0001212 48.0
WH3_k127_11367115_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 552.0
WH3_k127_11367115_1 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 454.0
WH3_k127_11367115_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003531 252.0
WH3_k127_11367115_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000005533 188.0
WH3_k127_11367115_4 PFAM Cobalt transport protein K02008 - - 0.000000000000000000000000000000001111 141.0
WH3_k127_11367115_5 COG0310 ABC-type Co2 transport system, permease component K02007 - - 0.000000000000000000000004584 106.0
WH3_k127_11367115_6 - K16915 - - 0.00000004438 62.0
WH3_k127_11367115_7 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.000002799 53.0
WH3_k127_11367115_8 Domain of unknown function (DUF4198) - - - 0.0004034 51.0
WH3_k127_11368565_0 PFAM aldo keto reductase K07079 - - 4.387e-228 711.0
WH3_k127_11368565_1 PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
WH3_k127_11368565_2 PFAM helix-turn-helix HxlR type - - - 0.00000000000000000000000000000000000000000000000000000000000001183 216.0
WH3_k127_11452807_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 594.0
WH3_k127_11452807_1 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 547.0
WH3_k127_11452807_10 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000006862 183.0
WH3_k127_11452807_11 PFAM Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000002339 150.0
WH3_k127_11452807_2 Male sterility protein K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 482.0
WH3_k127_11452807_3 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 484.0
WH3_k127_11452807_4 TIGRFAM dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 398.0
WH3_k127_11452807_5 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 327.0
WH3_k127_11452807_6 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 286.0
WH3_k127_11452807_7 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000005394 261.0
WH3_k127_11452807_8 Probable transposase K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001608 241.0
WH3_k127_11452807_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000004989 196.0
WH3_k127_11469658_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 587.0
WH3_k127_11469658_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 432.0
WH3_k127_11469658_10 Transcriptional regulator, TrmB - - - 0.000000000000000000000000000000000004942 141.0
WH3_k127_11469658_11 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.0000000000000000000000000004019 117.0
WH3_k127_11469658_12 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000001041 119.0
WH3_k127_11469658_13 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000001125 91.0
WH3_k127_11469658_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000001418 89.0
WH3_k127_11469658_15 FeoA K04758 - - 0.0000000006493 63.0
WH3_k127_11469658_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 342.0
WH3_k127_11469658_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 321.0
WH3_k127_11469658_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000179 274.0
WH3_k127_11469658_5 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000001794 236.0
WH3_k127_11469658_6 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000379 230.0
WH3_k127_11469658_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000004622 208.0
WH3_k127_11469658_8 Ribbon-helix-helix protein, copG family - - - 0.0000000000000000000000000000000000000000000000000000003149 199.0
WH3_k127_11469658_9 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000001224 162.0
WH3_k127_1149290_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 8.868e-207 654.0
WH3_k127_1149290_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 289.0
WH3_k127_1149290_2 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003976 242.0
WH3_k127_1149290_3 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000005198 211.0
WH3_k127_1149290_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000003229 215.0
WH3_k127_1149290_5 Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000000000000004487 195.0
WH3_k127_1149290_6 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000004415 182.0
WH3_k127_1149290_7 Rhomboid family K07059 - - 0.00000000000000000000000000000000000003372 155.0
WH3_k127_1149290_8 Met-10+ like-protein - - - 0.0000000000000000000000000001547 127.0
WH3_k127_1149290_9 PFAM Nickel transport complex, NikM subunit, transmembrane K02009 - - 0.00001523 56.0
WH3_k127_11562283_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14392 - - 8.651e-211 663.0
WH3_k127_11562283_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 571.0
WH3_k127_11562283_10 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000001281 177.0
WH3_k127_11562283_11 Belongs to the UPF0147 family K09721 - - 0.000000000000000000000000000000005806 130.0
WH3_k127_11562283_12 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.000000000000000000000000000001096 128.0
WH3_k127_11562283_13 Non-histone chromosomal protein MC1 - - - 0.0000000000000000000000000003053 115.0
WH3_k127_11562283_14 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.00000000000007668 78.0
WH3_k127_11562283_15 Metallo-beta-lactamase superfamily K02238 - - 0.0000000007497 71.0
WH3_k127_11562283_16 SigmaK-factor processing regulatory protein BofA - - - 0.000000009088 59.0
WH3_k127_11562283_2 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 549.0
WH3_k127_11562283_3 phosphoserine phosphatase activity K01079,K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 524.0
WH3_k127_11562283_4 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000744 286.0
WH3_k127_11562283_5 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000005475 263.0
WH3_k127_11562283_6 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000005632 248.0
WH3_k127_11562283_7 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000008115 223.0
WH3_k127_11562283_8 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000001421 202.0
WH3_k127_11562283_9 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.00000000000000000000000000000000000000000000000006061 184.0
WH3_k127_11572359_0 Flavin containing amine oxidoreductase - - - 5.129e-211 662.0
WH3_k127_11572359_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.072e-199 632.0
WH3_k127_11572359_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001835 270.0
WH3_k127_11572359_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000001355 113.0
WH3_k127_11572359_4 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000001641 56.0
WH3_k127_11704084_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 430.0
WH3_k127_11704084_1 COG1226 Kef-type K transport systems K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 258.0
WH3_k127_11704084_2 Transposase - - - 0.0000000009091 61.0
WH3_k127_11704084_3 RNA-binding protein homologous to eukaryotic snRNP - - - 0.00008326 45.0
WH3_k127_11753224_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.751e-234 753.0
WH3_k127_11753224_1 PFAM PilT protein domain protein K06865 - - 2.465e-215 684.0
WH3_k127_11753224_10 - - - - 0.0000000000000000000000000000000000001649 144.0
WH3_k127_11753224_11 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000707 114.0
WH3_k127_11753224_12 Protein of unknown function (DUF2551) - - - 0.000000000000000000004524 96.0
WH3_k127_11753224_13 TIGRFAM transposase, IS605 OrfB family K07496 - - 0.00000000000000000003759 95.0
WH3_k127_11753224_14 Cna B domain protein - - - 0.0000000000001543 76.0
WH3_k127_11753224_2 PFAM AIR synthase related protein K07388 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 592.0
WH3_k127_11753224_3 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 565.0
WH3_k127_11753224_4 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 340.0
WH3_k127_11753224_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 337.0
WH3_k127_11753224_6 - - - - 0.00000000000000000000000000000000000000000000000005952 180.0
WH3_k127_11753224_7 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000004122 166.0
WH3_k127_11753224_8 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000000003965 165.0
WH3_k127_11753224_9 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000008242 153.0
WH3_k127_1175634_0 alpha amylase, C-terminal all-beta - - - 2.162e-267 836.0
WH3_k127_1175634_1 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 369.0
WH3_k127_1175634_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000002529 173.0
WH3_k127_1175634_3 - - - - 0.0000000000000000000000000000000000000000001671 174.0
WH3_k127_1175634_4 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000001505 154.0
WH3_k127_1175634_5 MarR family - - - 0.000000000000000000000000000000000000004361 151.0
WH3_k127_1175634_6 Thioredoxin K03671 - - 0.00000000000000000000000000000000000001355 155.0
WH3_k127_1175634_7 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000003256 126.0
WH3_k127_1175634_8 solute binding protein K02035 - - 0.00000000000000000007131 102.0
WH3_k127_1175634_9 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0001879 47.0
WH3_k127_11842706_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 6.329e-224 712.0
WH3_k127_11842706_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 541.0
WH3_k127_11842706_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 430.0
WH3_k127_11842706_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 366.0
WH3_k127_11842706_4 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 306.0
WH3_k127_11842706_5 PFAM DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 295.0
WH3_k127_11845182_0 CobN/Magnesium Chelatase K02230 - 6.6.1.2 0.0 1248.0
WH3_k127_11845182_1 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000001396 221.0
WH3_k127_11845182_2 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000001887 218.0
WH3_k127_11845182_3 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000003062 182.0
WH3_k127_11845182_4 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.00000000000000000000007825 106.0
WH3_k127_11845182_5 Adenosylcobinamide amidohydrolase K02013,K02231 - 2.7.1.156,2.7.7.62,3.6.3.34 0.00000000000000000002779 93.0
WH3_k127_11852399_0 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 509.0
WH3_k127_11852399_1 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 371.0
WH3_k127_11852399_2 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 319.0
WH3_k127_11852399_3 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 289.0
WH3_k127_11852399_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000007329 244.0
WH3_k127_11852399_5 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000000008633 222.0
WH3_k127_11852399_6 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000001252 126.0
WH3_k127_11852399_7 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000001224 86.0
WH3_k127_11856853_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 298.0
WH3_k127_11856853_1 integral membrane protein K07027 - - 0.000000000000000000000000000000000000000000000000002517 196.0
WH3_k127_11856853_2 Family of unknown function (DUF5350) - - - 0.0000000000152 66.0
WH3_k127_1186147_0 Necessary for normal cell division and for the maintenance of normal septation - - - 0.000000000000000000000000000000000000000000000000000000002793 211.0
WH3_k127_1186147_1 COG0668 Small-conductance mechanosensitive channel K16052 - - 0.00000000000000000000000000000000000000000000005399 181.0
WH3_k127_1186147_2 Mediates influx of magnesium ions K03284 - - 0.00000000007315 63.0
WH3_k127_11861617_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 2.085e-242 762.0
WH3_k127_11861617_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 3.19e-199 632.0
WH3_k127_11861617_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 457.0
WH3_k127_11861617_3 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000005673 208.0
WH3_k127_11861617_4 Domain of unknown function DUF1828 - - - 0.00000000000000000000000000000000000000000000000000000001658 200.0
WH3_k127_11861617_5 tetratricopeptide repeat - - - 0.0000001587 55.0
WH3_k127_11978255_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1120.0
WH3_k127_11978255_1 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000000000000000000003427 203.0
WH3_k127_11978255_2 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.0000000000000000000000000000001287 132.0
WH3_k127_11978255_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000005108 105.0
WH3_k127_11978255_4 Pentapeptide repeats (9 copies) - - - 0.0000000000002885 77.0
WH3_k127_11978255_5 SMART Peptidase A22, presenilin signal peptide - - - 0.0003365 45.0
WH3_k127_12024720_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.88e-294 923.0
WH3_k127_12024720_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.109e-290 901.0
WH3_k127_12024720_2 PFAM Fic DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 411.0
WH3_k127_12024720_3 PFAM Radical SAM - - - 0.00000000000000255 79.0
WH3_k127_12085478_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 363.0
WH3_k127_12085478_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 301.0
WH3_k127_12085478_2 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000104 148.0
WH3_k127_12085478_3 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000007093 69.0
WH3_k127_12085478_4 protein (ATP-grasp superfamily) K07159 - - 0.00000000003577 64.0
WH3_k127_12177972_0 - - - - 0.00000000000000000000000000000008285 130.0
WH3_k127_12177972_1 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.0000000000000000000000003264 107.0
WH3_k127_12177972_2 DNA methylase K00571,K07316 - 2.1.1.72 0.000000000000000000007138 95.0
WH3_k127_12177972_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000005005 71.0
WH3_k127_12177972_4 - - - - 0.0002229 48.0
WH3_k127_12353023_0 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000001189 190.0
WH3_k127_12353023_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000005909 136.0
WH3_k127_12353023_2 COG1522 Transcriptional regulators - - - 0.000000763 55.0
WH3_k127_12374536_0 SMART regulatory protein AsnC Lrp family K22225 - - 0.00000000000000000000000000000000000000000000007762 174.0
WH3_k127_12374536_1 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000001624 146.0
WH3_k127_12374536_2 Periplasmic copper-binding protein (NosD) - - - 0.00005988 53.0
WH3_k127_12376752_0 DEAD DEAH box helicase domain protein K03725 - - 3.18e-218 703.0
WH3_k127_12376752_1 Uncharacterized protein conserved in archaea (DUF2114) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 594.0
WH3_k127_12376752_2 SMART regulatory protein, Crp K07730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 333.0
WH3_k127_12376752_3 ArsR transcriptional regulator - - - 0.0000000000000000003199 90.0
WH3_k127_12376752_4 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000002053 63.0
WH3_k127_12377010_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 510.0
WH3_k127_12377010_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001964 276.0
WH3_k127_12377010_2 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000069 260.0
WH3_k127_12377010_3 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000000000000000000005266 233.0
WH3_k127_12377010_4 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000000000005717 156.0
WH3_k127_12377010_5 Non-histone chromosomal protein MC1 - - - 0.0000000000000000000000000000002356 125.0
WH3_k127_12406962_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001151 280.0
WH3_k127_12406962_1 ABC-type multidrug transport system ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000006926 223.0
WH3_k127_12406962_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000001294 179.0
WH3_k127_12416118_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 1.191e-241 756.0
WH3_k127_12416118_1 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 319.0
WH3_k127_12416118_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000196 104.0
WH3_k127_12416118_3 - - - - 0.00000000000000001249 89.0
WH3_k127_12416118_4 Lamin Tail Domain - - - 0.0000000000002085 79.0
WH3_k127_12416118_5 Transcriptional regulator - - - 0.0000000000168 69.0
WH3_k127_12416118_6 Pkd domain containing protein - - - 0.0000001347 64.0
WH3_k127_12479591_0 PFAM integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 415.0
WH3_k127_12479591_1 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007922 266.0
WH3_k127_12479591_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000009625 256.0
WH3_k127_12479591_3 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000000000000000000000000000000000000000000002657 213.0
WH3_k127_12479591_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000004753 192.0
WH3_k127_12479591_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000007408 187.0
WH3_k127_12479591_6 - - - - 0.0000000000000000000000002291 113.0
WH3_k127_12479591_7 - - - - 0.000006919 55.0
WH3_k127_12496436_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 409.0
WH3_k127_12496436_1 transcription activator, effector binding - - - 0.00000000000000000000000000000000000000000001429 166.0
WH3_k127_12496436_2 Transposase IS200 like K07491 - - 0.0000000002945 62.0
WH3_k127_12496436_3 Transposase - - - 0.0000004722 51.0
WH3_k127_12547240_0 Glycosyl hydrolase family 26 - - - 0.000000000000000000000000003444 130.0
WH3_k127_1265794_0 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000003935 217.0
WH3_k127_1265794_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000007731 194.0
WH3_k127_1265794_2 Polyprenyl synthetase K02523 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.90 0.0000000000000000000000000000000000000000000000000006841 195.0
WH3_k127_1265794_3 CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000000000004288 180.0
WH3_k127_1265794_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000001339 173.0
WH3_k127_1265794_5 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000004341 95.0
WH3_k127_12690710_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 409.0
WH3_k127_12690710_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 321.0
WH3_k127_12691282_0 type I site-specific deoxyribonuclease activity K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 595.0
WH3_k127_12691282_1 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000007104 154.0
WH3_k127_12762448_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 434.0
WH3_k127_12762448_1 phosphoesterase RecJ domain protein K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 303.0
WH3_k127_12762448_2 HTH-type transcriptional regulatory protein K07728 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 291.0
WH3_k127_12762448_3 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009111 280.0
WH3_k127_12762448_4 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000001083 213.0
WH3_k127_12762448_5 PFAM thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000007377 165.0
WH3_k127_12762448_6 - - - - 0.00000000000000005094 83.0
WH3_k127_12762448_7 archaeal coiled-coil protein - - - 0.0000402 49.0
WH3_k127_12810731_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 507.0
WH3_k127_12810731_1 Metallo-beta-lactamase superfamily - - - 0.0000006176 57.0
WH3_k127_12889659_0 PFAM ABC transporter K00400 - - 7.675e-213 672.0
WH3_k127_12889659_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 572.0
WH3_k127_12889659_2 Belongs to the UPF0288 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 457.0
WH3_k127_12889659_3 methanogenesis marker protein 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 371.0
WH3_k127_12889659_4 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.000000000000000000000000000000000000000000000000006588 184.0
WH3_k127_12889659_5 - - - - 0.0000000000000000000000000000000000000000000002387 174.0
WH3_k127_12889659_6 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.00000000000000000000000000000000001109 143.0
WH3_k127_12889659_7 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.0000000000000000000000000000000008345 135.0
WH3_k127_12889659_8 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000004303 117.0
WH3_k127_12889659_9 DNA-binding transcription factor activity - - - 0.000000000007869 71.0
WH3_k127_13046100_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 401.0
WH3_k127_13046100_1 Protein of unknown function (DUF1016) - - - 0.000000000000000000000000000000000000000000000001052 180.0
WH3_k127_13046100_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000169 91.0
WH3_k127_13068235_0 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 551.0
WH3_k127_13068235_1 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 526.0
WH3_k127_13068235_2 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 372.0
WH3_k127_13068235_3 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000004723 111.0
WH3_k127_13104562_0 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000006656 228.0
WH3_k127_13104562_1 Acyl-CoA thioester hydrolase/BAAT N-terminal region K06889 - - 0.000000000000000000000000000000000000000001577 165.0
WH3_k127_13104562_2 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000003351 118.0
WH3_k127_13104562_3 4Fe-4S binding domain - - - 0.000000000001962 70.0
WH3_k127_13104562_4 4Fe-4S binding domain - - - 0.0000000846 56.0
WH3_k127_13104562_5 4Fe-4S binding domain - - - 0.000005778 50.0
WH3_k127_13143731_0 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 323.0
WH3_k127_13143731_1 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000007712 261.0
WH3_k127_13145709_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1315.0
WH3_k127_13145709_1 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 364.0
WH3_k127_13145709_2 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000000000000000000000000001396 209.0
WH3_k127_13145709_3 methyltransferase activity - - - 0.00000000000000000000000000000000000000000001116 172.0
WH3_k127_13145709_4 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.00000000000000000000000000004413 121.0
WH3_k127_13145709_5 nucleotidyltransferase activity K07076 - - 0.00000000000000003162 86.0
WH3_k127_13234730_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 484.0
WH3_k127_13234730_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 443.0
WH3_k127_13234730_2 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 436.0
WH3_k127_13234730_3 PFAM amino acid-binding ACT domain protein K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 297.0
WH3_k127_13234730_4 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 295.0
WH3_k127_13234730_5 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004891 261.0
WH3_k127_13234730_6 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.00000000000000000000000000000000000005743 144.0
WH3_k127_13234730_7 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 0.0000000000000000000000009008 118.0
WH3_k127_13234730_8 COG3634 Alkyl hydroperoxide reductase, large subunit - - - 0.0000000000000000000193 96.0
WH3_k127_13234730_9 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.000000000000005861 76.0
WH3_k127_13253413_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 589.0
WH3_k127_13253413_1 Restriction endonuclease K07448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 372.0
WH3_k127_13253413_2 N-6 DNA Methylase - - - 0.0000000000000000000000000000000000000000000000000000000000001233 215.0
WH3_k127_13253413_3 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000000000000000000000002979 105.0
WH3_k127_13253413_4 TIGRFAM addiction module toxin, RelE StbE family K19158 - - 0.00007211 49.0
WH3_k127_13401136_0 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 6.63e-255 796.0
WH3_k127_13401136_1 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 588.0
WH3_k127_13401136_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 484.0
WH3_k127_13401136_3 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 328.0
WH3_k127_13401136_4 Methyl-coenzyme M reductase operon protein D K03422 - - 0.000000000000000000000000000000000002179 143.0
WH3_k127_13428232_0 N-6 DNA Methylase - - - 7.804e-221 699.0
WH3_k127_13455747_0 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000000000000361 215.0
WH3_k127_13455747_1 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.000000000000000000000000000000000000004694 152.0
WH3_k127_13455747_2 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000000000000000007308 107.0
WH3_k127_13455747_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.000000000000000003409 90.0
WH3_k127_13455747_4 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002869 74.0
WH3_k127_13455747_5 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.000000000002093 68.0
WH3_k127_13460897_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 560.0
WH3_k127_13460897_1 Putative transposase DNA-binding domain - - - 0.0000000002142 63.0
WH3_k127_134757_0 PFAM Sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000001328 268.0
WH3_k127_134757_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000005827 171.0
WH3_k127_134757_2 phosphatidylinositol metabolic process K00728 - 2.4.1.109 0.00000000000000000000000000000000000005015 155.0
WH3_k127_13478165_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 0.0 1014.0
WH3_k127_13478165_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 4.016e-204 642.0
WH3_k127_13478165_10 Large family of predicted nucleotide-binding domains K07064 - - 0.000000000000002731 81.0
WH3_k127_13478165_11 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000002711 78.0
WH3_k127_13478165_12 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000295 69.0
WH3_k127_13478165_13 - - - - 0.000000005066 61.0
WH3_k127_13478165_14 - - - - 0.00000001519 59.0
WH3_k127_13478165_15 PFAM acylphosphatase K01512 - 3.6.1.7 0.000001522 55.0
WH3_k127_13478165_16 Possibly the antitoxin component of a type II toxin- antitoxin (TA) system - - - 0.000004617 50.0
WH3_k127_13478165_17 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00008661 46.0
WH3_k127_13478165_18 Domain of unknown function (DUF3368) K07066 - - 0.0001109 46.0
WH3_k127_13478165_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 361.0
WH3_k127_13478165_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 344.0
WH3_k127_13478165_4 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000009769 171.0
WH3_k127_13478165_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000004122 166.0
WH3_k127_13478165_6 Belongs to the acylphosphatase family - - - 0.000000000000000000000000000000000000000002787 163.0
WH3_k127_13478165_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000009929 119.0
WH3_k127_13478165_8 Belongs to the acylphosphatase family - - - 0.00000000000000000000926 100.0
WH3_k127_13478165_9 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000009576 83.0
WH3_k127_13524035_0 membrane - - - 0.0000000000000000000000000000000000000001089 160.0
WH3_k127_13524035_1 Belongs to the P(II) protein family K02589 - - 0.000000000000000000000000000005831 122.0
WH3_k127_13524035_2 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000004578 102.0
WH3_k127_13524035_3 Transposase, Mutator family - - - 0.000000000000000000336 91.0
WH3_k127_13524035_4 Transposase K07484 - - 0.0000000000000007111 81.0
WH3_k127_13524035_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000976 71.0
WH3_k127_13524035_6 serine-type aminopeptidase activity K14475 - - 0.00000001917 61.0
WH3_k127_1352441_0 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000000000000000000000003173 231.0
WH3_k127_1352441_1 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000000000000000000000000000000000000413 156.0
WH3_k127_1352441_2 MTH865-like family - - - 0.00000000000000000000000000006329 117.0
WH3_k127_13609461_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008646 283.0
WH3_k127_13609461_1 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000351 231.0
WH3_k127_13609461_2 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000001241 181.0
WH3_k127_13660534_0 shikimate kinase activity K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 297.0
WH3_k127_13660534_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000001119 179.0
WH3_k127_13660534_2 Lycopene cyclase protein - - - 0.000000000000000000000000000000000009501 142.0
WH3_k127_13660534_3 chorismate mutase K04093 - 5.4.99.5 0.00000000000000001301 85.0
WH3_k127_13660534_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000006566 88.0
WH3_k127_13675271_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 400.0
WH3_k127_13675271_1 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 326.0
WH3_k127_13675271_2 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 308.0
WH3_k127_13675271_3 Belongs to the UPF0179 family K09730 - - 0.000000000000000000000000000000000000000001652 160.0
WH3_k127_13684403_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 8.504e-202 638.0
WH3_k127_13684403_1 COG0477 Permeases of the major facilitator superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 569.0
WH3_k127_13684403_10 RNA-binding protein (contains PUA domain) K07575 - - 0.0000000000000000000000000000000000000002271 156.0
WH3_k127_13684403_11 SMART regulatory protein AsnC Lrp family K22225 - - 0.00000000000000000000000000000000000001649 151.0
WH3_k127_13684403_12 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.000000000000000000000003378 112.0
WH3_k127_13684403_13 PFAM Thioredoxin K03671 - - 0.0000000000000000000002508 98.0
WH3_k127_13684403_14 binds to the 23S rRNA K02922 - - 0.000000000000000006835 83.0
WH3_k127_13684403_2 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 498.0
WH3_k127_13684403_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 339.0
WH3_k127_13684403_4 Glycosyl transferase family 21 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 332.0
WH3_k127_13684403_5 Metallo-beta-lactamase superfamily K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 321.0
WH3_k127_13684403_6 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 320.0
WH3_k127_13684403_7 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 289.0
WH3_k127_13684403_8 Bacterial transferase hexapeptide K02617 - - 0.00000000000000000000000000000000000000000000000005346 184.0
WH3_k127_13684403_9 - - - - 0.0000000000000000000000000000000000000000002202 177.0
WH3_k127_1374484_0 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 493.0
WH3_k127_1374484_1 NAD-dependent epimerase dehydratase K01784,K03274 - 5.1.3.2,5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 307.0
WH3_k127_1374484_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000001871 220.0
WH3_k127_1374484_3 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000001998 205.0
WH3_k127_13818452_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0 1008.0
WH3_k127_13818452_1 PFAM ferredoxin-dependent glutamate synthase - - - 7.352e-296 913.0
WH3_k127_13818452_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 5.28e-229 719.0
WH3_k127_13818452_3 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 565.0
WH3_k127_13818452_4 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 291.0
WH3_k127_13818452_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002577 251.0
WH3_k127_13818452_6 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000006575 203.0
WH3_k127_13818452_7 NYN domain - - - 0.0000000000000000000000000000000000000000000000000003169 193.0
WH3_k127_13818452_8 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000002142 79.0
WH3_k127_13818452_9 PFAM Oxidoreductase FAD NAD(P)-binding K00528 - 1.18.1.2,1.19.1.1 0.00000001339 56.0
WH3_k127_139619_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 336.0
WH3_k127_139619_1 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003449 269.0
WH3_k127_139619_2 Domain of unknown function (DUF4258) - - - 0.0000000000000000000007638 98.0
WH3_k127_139619_3 mRNA binding - - - 0.000000000000000000001286 95.0
WH3_k127_139619_4 - - - - 0.0000000000000000002128 93.0
WH3_k127_139619_5 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000004649 83.0
WH3_k127_139619_6 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000005013 81.0
WH3_k127_1438398_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.562e-235 739.0
WH3_k127_1438398_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 423.0
WH3_k127_1438398_2 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 406.0
WH3_k127_1438398_3 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000002939 158.0
WH3_k127_1438398_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000003237 128.0
WH3_k127_148625_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 459.0
WH3_k127_148625_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 310.0
WH3_k127_148625_2 PFAM Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003166 270.0
WH3_k127_148625_3 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000003212 224.0
WH3_k127_148625_4 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000004635 235.0
WH3_k127_148625_5 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000001403 210.0
WH3_k127_148625_6 - - - - 0.000000000000000000000000000000000000395 147.0
WH3_k127_1508152_0 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000004451 231.0
WH3_k127_1508152_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000006526 216.0
WH3_k127_1576332_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 485.0
WH3_k127_1716710_0 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000001541 177.0
WH3_k127_1716710_1 peptidase M24 K01262 - 3.4.11.9 0.00000002666 55.0
WH3_k127_17245_0 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 306.0
WH3_k127_17245_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000006741 242.0
WH3_k127_17245_2 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000003571 81.0
WH3_k127_1837678_0 deaminase K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 293.0
WH3_k127_1837678_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000008335 114.0
WH3_k127_1837678_2 oxidoreductase activity - - - 0.000000000000000000279 102.0
WH3_k127_1837678_3 GXGXG motif K00202 - 1.2.7.12 0.00000000002854 73.0
WH3_k127_1837678_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000006748 61.0
WH3_k127_1913749_0 nucleoside recognition domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 454.0
WH3_k127_1913749_1 nucleoside recognition domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001183 258.0
WH3_k127_1913749_2 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.0000000000000000000000000000000000000000002306 164.0
WH3_k127_1913749_3 - - - - 0.00000000000000000001805 98.0
WH3_k127_1913749_4 PFAM FeoA family protein K04758 - - 0.000000000000000002344 87.0
WH3_k127_1913749_5 PFAM Cache, type 2 domain protein - - - 0.000000000000000173 81.0
WH3_k127_1913749_6 FeoA K04758 - - 0.000000000000000373 80.0
WH3_k127_1913749_7 - - - - 0.0002943 51.0
WH3_k127_19410_0 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000009557 159.0
WH3_k127_19410_1 protein (ATP-grasp superfamily) K07159 - - 0.0000000000000000000001597 105.0
WH3_k127_1949332_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 436.0
WH3_k127_1949332_1 Belongs to the UPF0284 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 314.0
WH3_k127_1949332_2 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 293.0
WH3_k127_1996284_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 5.379e-204 655.0
WH3_k127_1996284_1 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 355.0
WH3_k127_1996284_2 Glycosyltransferase Family 4 K00743 - 2.4.1.87 0.00000000000000000000000000000000000000000000000005575 184.0
WH3_k127_1996284_3 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000005491 140.0
WH3_k127_1996284_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000006528 138.0
WH3_k127_1996284_5 Belongs to the acylphosphatase family - - - 0.00000000000000001264 88.0
WH3_k127_1996284_6 RHS Repeat - - - 0.00000000001284 79.0
WH3_k127_2008179_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 544.0
WH3_k127_2008179_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000005708 115.0
WH3_k127_2051598_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 374.0
WH3_k127_2051598_1 - - - - 0.00000000000003623 74.0
WH3_k127_2205872_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 594.0
WH3_k127_2205872_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 545.0
WH3_k127_2205872_2 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000005081 83.0
WH3_k127_2205872_3 Cation transporter/ATPase, N-terminus - - - 0.0001278 45.0
WH3_k127_2242628_0 PFAM ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 292.0
WH3_k127_2242628_1 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000002621 189.0
WH3_k127_2255698_0 Methyltransferase K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 329.0
WH3_k127_2255698_1 domain protein - - - 0.00000000000000000000000000000000000000000000000000006847 214.0
WH3_k127_2255698_2 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000808 162.0
WH3_k127_2255698_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000001066 89.0
WH3_k127_2286580_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.671e-202 638.0
WH3_k127_2286580_1 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 394.0
WH3_k127_2286580_2 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 317.0
WH3_k127_2286580_3 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000003024 237.0
WH3_k127_2286580_4 Involved in cell shape control K22222 - - 0.000000000000000000000000000000000000000000000000000005572 196.0
WH3_k127_2286580_5 ChaB K06197 - - 0.0000000000006524 72.0
WH3_k127_2286580_6 pilus organization - - - 0.000000000003264 72.0
WH3_k127_231186_0 Transporter Family - - - 0.000000000000000000000000000000000000000000000000000004404 198.0
WH3_k127_231186_1 Permease - - - 0.0000000000000000000000000000000000000001421 164.0
WH3_k127_231186_2 Probable transposase K07496 - - 0.000000000000003748 76.0
WH3_k127_231186_3 Domain of unknown function (DUF3786) - - - 0.000000000002914 74.0
WH3_k127_2335074_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 329.0
WH3_k127_2335074_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000003656 209.0
WH3_k127_2448484_0 Tetratricopeptide repeat K12600 - - 0.000000000000000000000000000000000000000000001002 182.0
WH3_k127_2448484_1 PFAM Protein kinase domain - - - 0.0000000000000000000000000000000003149 143.0
WH3_k127_2448484_2 PFAM Protein kinase domain - - - 0.00000000000000000000003694 108.0
WH3_k127_2448484_3 Transcriptional regulator - - - 0.00002264 56.0
WH3_k127_2510657_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 498.0
WH3_k127_2510657_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 354.0
WH3_k127_2510657_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003707 282.0
WH3_k127_2510657_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004921 239.0
WH3_k127_2510657_4 COG1404 Subtilisin-like serine proteases K09607 - - 0.00000000000000000000000000000000000000000000000000000000000000000004512 243.0
WH3_k127_2510657_5 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000001477 164.0
WH3_k127_2510657_6 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000002 100.0
WH3_k127_2510657_7 PFAM Carbon starvation protein CstA K06200 - - 0.000001104 50.0
WH3_k127_2538799_0 PFAM Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 293.0
WH3_k127_2538799_1 mRNA binding - - - 0.0000000000000004062 80.0
WH3_k127_2538799_2 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000002745 76.0
WH3_k127_256005_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 5.168e-248 784.0
WH3_k127_2574535_0 COG1132 ABC-type multidrug transport system, ATPase and permease components K02068,K06147,K06148,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 526.0
WH3_k127_2574535_1 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 458.0
WH3_k127_2574535_10 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000004695 163.0
WH3_k127_2574535_11 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000006854 138.0
WH3_k127_2574535_12 histidine kinase A domain protein - - - 0.00000000000000000000000000004357 121.0
WH3_k127_2574535_13 Non-histone chromosomal protein MC1 - - - 0.0000000000000000000000000002691 119.0
WH3_k127_2574535_14 PFAM nucleoside recognition domain protein - - - 0.000000000001083 78.0
WH3_k127_2574535_2 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 427.0
WH3_k127_2574535_3 (ABC) transporter K06147,K06148,K16014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 431.0
WH3_k127_2574535_4 ATPases associated with a variety of cellular activities K02074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 357.0
WH3_k127_2574535_5 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000001164 250.0
WH3_k127_2574535_6 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002666 237.0
WH3_k127_2574535_7 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000006191 235.0
WH3_k127_2574535_8 formylmethanofuran dehydrogenase, subunit E - - - 0.00000000000000000000000000000000000000000000000000000003568 200.0
WH3_k127_2574535_9 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000838 200.0
WH3_k127_2586032_0 Alkyl sulfatase dimerisation - - - 2.383e-304 944.0
WH3_k127_2586032_1 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 1.122e-262 822.0
WH3_k127_2586032_10 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000139 206.0
WH3_k127_2586032_11 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000007781 175.0
WH3_k127_2586032_12 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000005352 151.0
WH3_k127_2586032_13 Homeodomain-like domain - - - 0.00000000000000000000000000000000000004583 148.0
WH3_k127_2586032_14 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000002964 136.0
WH3_k127_2586032_15 Neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000001565 121.0
WH3_k127_2586032_16 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000000004033 103.0
WH3_k127_2586032_17 PFAM Cache, type 2 domain protein - - - 0.0000000000000000000355 91.0
WH3_k127_2586032_18 - K00960 - 2.7.7.6 0.0000000000000003906 80.0
WH3_k127_2586032_19 TM2 domain - - - 0.00000000000001783 79.0
WH3_k127_2586032_2 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 1.35e-202 647.0
WH3_k127_2586032_20 - - - - 0.0000000000009653 72.0
WH3_k127_2586032_3 PFAM Aminotransferase class I and II K00812,K10907,K14287 - 2.6.1.1,2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009894 537.0
WH3_k127_2586032_4 His Kinase A (phospho-acceptor) domain K11443 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 432.0
WH3_k127_2586032_5 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 345.0
WH3_k127_2586032_6 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 353.0
WH3_k127_2586032_7 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 308.0
WH3_k127_2586032_8 MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000551 253.0
WH3_k127_2586032_9 PFAM Appr-1-p processing - - - 0.00000000000000000000000000000000000000000000000000000000000000003394 227.0
WH3_k127_2635969_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 3.409e-197 633.0
WH3_k127_2635969_1 PFAM Binding-protein-dependent transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 404.0
WH3_k127_2635969_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000003573 214.0
WH3_k127_2635969_3 TspO/MBR family K05770 - - 0.00000000000000000000000000000000000000000000000003161 184.0
WH3_k127_2635969_4 tRNA m6t6A37 methyltransferase activity K01628,K11261 - 1.2.7.12,4.1.2.17 0.00000000000000000000000000000000000000000000007438 172.0
WH3_k127_2635969_5 PFAM formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.00000000002486 66.0
WH3_k127_2670193_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 507.0
WH3_k127_2670193_1 Methanogenesis marker protein 8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 330.0
WH3_k127_2670193_2 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 294.0
WH3_k127_2670193_3 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000001103 218.0
WH3_k127_2670193_4 COG1498 Protein implicated in ribosomal biogenesis, Nop56p homolog K14564 - - 0.00000000000000000000000000000000000001437 150.0
WH3_k127_2670193_5 Transcriptional regulator, TrmB - - - 0.000000000000000000000000001513 117.0
WH3_k127_2670193_6 protein conserved in archaea - - - 0.000000000000000000000000008395 112.0
WH3_k127_2674729_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 479.0
WH3_k127_2674729_1 Permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 451.0
WH3_k127_2674729_10 cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000003161 69.0
WH3_k127_2674729_11 - - - - 0.00000006877 57.0
WH3_k127_2674729_12 COG2897 Rhodanese-related sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000009788 63.0
WH3_k127_2674729_13 Catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0009088 51.0
WH3_k127_2674729_2 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 317.0
WH3_k127_2674729_3 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000001522 204.0
WH3_k127_2674729_4 Putative Fe-S cluster - - - 0.00000000000000000000000000000000000000000000000000000002967 199.0
WH3_k127_2674729_5 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0000000000000000000000000000000000035 141.0
WH3_k127_2674729_6 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.000000000000000000000000000000002318 133.0
WH3_k127_2674729_7 toxin-antitoxin pair type II binding - - - 0.00000000000000000000000002365 110.0
WH3_k127_2674729_8 Ferredoxin K05337 - - 0.00000000000000002355 84.0
WH3_k127_2674729_9 negative regulation of DNA recombination - - - 0.000000000000005254 88.0
WH3_k127_2723608_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 479.0
WH3_k127_2723608_1 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 438.0
WH3_k127_2723608_2 PINc domain ribonuclease K09006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 316.0
WH3_k127_2723608_3 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000007719 229.0
WH3_k127_2758493_0 PFAM Glycosyl transferase, group 1 K12996 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001103 265.0
WH3_k127_2758493_1 glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000002024 198.0
WH3_k127_2758493_2 Polysaccharide biosynthesis protein - - - 0.0000000000002243 74.0
WH3_k127_2935388_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 582.0
WH3_k127_2935388_1 Cyclophilin-like K09143 - - 0.0000000000000000000000005632 105.0
WH3_k127_2935388_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000009161 49.0
WH3_k127_2975422_0 Histone deacetylase domain - - - 2.262e-206 649.0
WH3_k127_2975422_1 Hydantoinase/oxoprolinase N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 624.0
WH3_k127_2975422_2 Glycosyltransferase 28 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 407.0
WH3_k127_2975422_3 PFAM peptidase - - - 0.000000000000000000000004998 109.0
WH3_k127_2975422_4 PFAM Major Facilitator Superfamily - - - 0.00002511 55.0
WH3_k127_3011712_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 1.984e-276 863.0
WH3_k127_3011712_1 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 631.0
WH3_k127_3011712_10 Belongs to the 5'(3')-deoxyribonucleotidase family K05967 - - 0.000000001446 66.0
WH3_k127_3011712_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 413.0
WH3_k127_3011712_3 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002709 283.0
WH3_k127_3011712_4 Acetyl xylan esterase (AXE1) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000184 235.0
WH3_k127_3011712_5 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000003096 210.0
WH3_k127_3011712_6 Polyketide cyclase dehydrase - - - 0.0000000000000000000000000000000000000000000006771 169.0
WH3_k127_3011712_7 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 0.000000000000000000000000000000007543 151.0
WH3_k127_3011712_8 Bacterial protein of unknown function (DUF937) - - - 0.000000000000001606 84.0
WH3_k127_3011712_9 Glucose / Sorbosone dehydrogenase - - - 0.0000000005773 75.0
WH3_k127_3054469_0 S-layer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 591.0
WH3_k127_3054469_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 429.0
WH3_k127_3054469_10 - - - - 0.0000000000005795 76.0
WH3_k127_3054469_11 Nuclease (SNase domain-containing protein) - - - 0.0000000008237 67.0
WH3_k127_3054469_12 Nuclease (SNase domain-containing protein) - - - 0.0000003848 59.0
WH3_k127_3054469_13 COG3436 Transposase and inactivated derivatives K07484 - - 0.000009705 49.0
WH3_k127_3054469_2 Cation transporter/ATPase, N-terminus K01531,K01535 - 3.6.3.2,3.6.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 415.0
WH3_k127_3054469_3 Transposase domain (DUF772) K07481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 368.0
WH3_k127_3054469_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 346.0
WH3_k127_3054469_5 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003728 266.0
WH3_k127_3054469_6 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000005609 159.0
WH3_k127_3054469_7 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.000000000000000000000000000021 123.0
WH3_k127_3054469_8 Thiamine-binding protein - - - 0.00000000000001215 78.0
WH3_k127_3054469_9 TIGRFAM CRISPR-associated protein, Csx3 family K19144 - - 0.00000000000008809 74.0
WH3_k127_3077687_0 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000000000000000000002079 239.0
WH3_k127_3077687_1 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000006346 235.0
WH3_k127_3077687_2 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000002673 69.0
WH3_k127_3077687_3 TIGRFAM transposase, IS605 OrfB family, central region K07496 - - 0.000000003542 58.0
WH3_k127_3115343_0 TIGRFAM formate dehydrogenase, alpha subunit K00336,K05299 - 1.17.1.10,1.6.5.3 2.511e-291 921.0
WH3_k127_3115343_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.27e-285 893.0
WH3_k127_3115343_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 501.0
WH3_k127_3115343_3 CRISPR-associated endoribonuclease Cas6 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000376 273.0
WH3_k127_3115343_4 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000001317 206.0
WH3_k127_3115343_5 TIGRFAM CRISPR locus-related DNA-binding protein K07725 - - 0.00000000000000000000000000000000000000000000001066 178.0
WH3_k127_3115343_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000003837 109.0
WH3_k127_3115343_7 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000001782 83.0
WH3_k127_3115343_8 Protein of unknown function DUF104 - - - 0.00001321 49.0
WH3_k127_3115690_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 359.0
WH3_k127_3115690_1 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000002097 224.0
WH3_k127_3115690_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000065 190.0
WH3_k127_3115690_3 PFAM Nucleoside 2-deoxyribosyltransferase - - - 0.00000000000000000000000001165 114.0
WH3_k127_3125600_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 574.0
WH3_k127_3125600_1 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 526.0
WH3_k127_3125600_10 Dodecin K09165 - - 0.0000000000000000000005214 96.0
WH3_k127_3125600_11 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000002098 89.0
WH3_k127_3125600_12 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000001124 77.0
WH3_k127_3125600_13 Mo-molybdopterin cofactor metabolic process K03753 - - 0.000000001897 60.0
WH3_k127_3125600_2 DEAD DEAH box helicase domain protein K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 373.0
WH3_k127_3125600_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 368.0
WH3_k127_3125600_4 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 337.0
WH3_k127_3125600_5 PFAM GTP-binding protein HSR1-related K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 315.0
WH3_k127_3125600_6 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000306 256.0
WH3_k127_3125600_7 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.000000000000000000000000000000000001504 141.0
WH3_k127_3125600_8 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000000000002128 119.0
WH3_k127_3125600_9 Zn-ribbon containing protein K07163 - - 0.00000000000000000000000002718 112.0
WH3_k127_3213066_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773,K18779 - 2.4.2.29,2.4.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 449.0
WH3_k127_3213066_1 PFAM Methyltransferase type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 300.0
WH3_k127_3213066_2 nucleoside recognition domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004741 240.0
WH3_k127_3213066_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000004129 132.0
WH3_k127_3213066_4 Secreted repeat of unknown function - - - 0.000000000000000000002493 99.0
WH3_k127_3213066_5 Ferritin-like domain K02217 - 1.16.3.2 0.0000000001914 63.0
WH3_k127_3215425_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 496.0
WH3_k127_3215425_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 447.0
WH3_k127_3215425_2 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 383.0
WH3_k127_3215425_3 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 309.0
WH3_k127_3215425_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 294.0
WH3_k127_3215425_5 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001243 235.0
WH3_k127_3215425_6 PBS lyase HEAT-like repeat - - - 0.00000000000000006967 91.0
WH3_k127_3215425_7 Uncharacterised protein family (UPF0153) K06940 - - 0.0001025 49.0
WH3_k127_3232126_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.149e-234 737.0
WH3_k127_3232126_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000201 212.0
WH3_k127_3232126_10 B-block binding subunit of TFIIIC - - - 0.0000004601 61.0
WH3_k127_3232126_11 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.0001727 48.0
WH3_k127_3232126_2 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000001126 191.0
WH3_k127_3232126_3 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000003446 170.0
WH3_k127_3232126_4 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.0000000000000000000000000000000000000000005658 166.0
WH3_k127_3232126_5 tpr repeat - - - 0.0000000000000000000000001643 109.0
WH3_k127_3232126_6 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00000000000000000003746 94.0
WH3_k127_3232126_7 Domain of unknown function (DUF1610) K07580 - - 0.000000000000000005159 84.0
WH3_k127_3232126_8 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000000001258 86.0
WH3_k127_3232126_9 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000003791 76.0
WH3_k127_3234281_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 2.925e-233 729.0
WH3_k127_3234281_1 4Fe-4S dicluster domain - - - 0.00000000000002036 74.0
WH3_k127_3289406_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 522.0
WH3_k127_3289406_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 501.0
WH3_k127_3289406_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000000000000000000002825 144.0
WH3_k127_3289406_3 ADP-specific Phosphofructokinase/Glucokinase conserved region K00918 - 2.7.1.146,2.7.1.147 0.0000000000003855 73.0
WH3_k127_3289406_4 Possibly the antitoxin component of a - - - 0.000000000006677 70.0
WH3_k127_3396980_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 9.589e-273 848.0
WH3_k127_3396980_1 4Fe-4S dicluster domain K00196 - - 0.00000000000000000000000000000000000000000000000003081 184.0
WH3_k127_3409122_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.022e-201 653.0
WH3_k127_3409122_1 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 396.0
WH3_k127_3409122_2 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 359.0
WH3_k127_3409122_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000009307 237.0
WH3_k127_3409122_4 repeat-containing protein - - - 0.00000000000000000000001243 107.0
WH3_k127_3414508_0 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 366.0
WH3_k127_3414508_1 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000007222 173.0
WH3_k127_3414508_2 Iron-sulfur cluster-binding domain - - - 0.000000000001678 72.0
WH3_k127_3549161_0 PFAM SOUL heme-binding protein - - - 0.0000000000000000000003343 102.0
WH3_k127_3549161_1 Fic/DOC family K07341 - - 0.000000000002812 73.0
WH3_k127_3551639_0 PFAM CobN Magnesium Chelatase K02230 - 6.6.1.2 0.0 1174.0
WH3_k127_3551639_1 Ferrous iron transport B domain protein K04759 - - 7.102e-235 742.0
WH3_k127_3551639_10 COG1321 Mn-dependent transcriptional regulator K03709 - - 0.00000000000000000000000000000000000002392 154.0
WH3_k127_3551639_11 lyase activity - - - 0.00000000000000000000000001698 126.0
WH3_k127_3551639_12 PFAM FeoA family protein K04758 - - 0.00000000000001223 76.0
WH3_k127_3551639_13 FecCD transport family K02015 - - 0.0000000003412 61.0
WH3_k127_3551639_15 - - - - 0.0000006494 56.0
WH3_k127_3551639_2 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 604.0
WH3_k127_3551639_3 ABC-type Fe3 -siderophore transport system, permease component K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 416.0
WH3_k127_3551639_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 342.0
WH3_k127_3551639_5 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 301.0
WH3_k127_3551639_6 PFAM Radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002439 264.0
WH3_k127_3551639_7 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000001887 226.0
WH3_k127_3551639_8 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000158 190.0
WH3_k127_3551639_9 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000000000000000000000000000003192 166.0
WH3_k127_3568862_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 535.0
WH3_k127_3568862_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 375.0
WH3_k127_3568862_10 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000001726 145.0
WH3_k127_3568862_11 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000000000000000000000005092 139.0
WH3_k127_3568862_12 binds to the 23S rRNA K02921 - - 0.00000000000000000000000000001554 119.0
WH3_k127_3568862_13 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000000000156 124.0
WH3_k127_3568862_14 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.00000000000000000000004081 107.0
WH3_k127_3568862_15 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000000000000000003462 89.0
WH3_k127_3568862_16 RNA binding K07581 - - 0.0000000000005376 74.0
WH3_k127_3568862_17 Putative zinc- or iron-chelating domain K06940 - - 0.00000000009884 70.0
WH3_k127_3568862_18 Predicted RNA-binding protein K06964 - - 0.0000000003857 62.0
WH3_k127_3568862_19 Transcription factor Pcc1 K09741 - - 0.00000000194 61.0
WH3_k127_3568862_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 366.0
WH3_k127_3568862_20 Probably involved in the biogenesis of the ribosome K14561 - - 0.0000004049 57.0
WH3_k127_3568862_21 Winged helix-turn-helix - - - 0.00004708 49.0
WH3_k127_3568862_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 335.0
WH3_k127_3568862_4 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 330.0
WH3_k127_3568862_5 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 329.0
WH3_k127_3568862_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 285.0
WH3_k127_3568862_7 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 260.0
WH3_k127_3568862_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002823 213.0
WH3_k127_3568862_9 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.00000000000000000000000000000000000000000000000005006 186.0
WH3_k127_3639203_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 617.0
WH3_k127_3639203_1 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000000000000000000000003145 192.0
WH3_k127_3639203_2 binds to the 23S rRNA K02876 - - 0.00000000000000000000003057 103.0
WH3_k127_374100_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 9.226e-282 873.0
WH3_k127_374100_1 Protein of unknown function (DUF1646) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 349.0
WH3_k127_374100_2 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000002007 186.0
WH3_k127_374100_3 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.00000000108 63.0
WH3_k127_3741184_0 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 563.0
WH3_k127_3741184_1 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000007915 213.0
WH3_k127_3741184_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000127 204.0
WH3_k127_3741184_3 NnrU protein K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000004962 206.0
WH3_k127_3812665_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.592e-239 754.0
WH3_k127_3812665_1 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000837 132.0
WH3_k127_3812665_2 Putative transposase DNA-binding domain - - - 0.00001771 48.0
WH3_k127_3869281_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 558.0
WH3_k127_3869281_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 352.0
WH3_k127_3869281_2 Ferritin-like domain K02217 - 1.16.3.2 0.000000000000000000000000000000000000000007922 158.0
WH3_k127_3869281_3 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000004265 102.0
WH3_k127_3950663_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000296 289.0
WH3_k127_3950663_1 Belongs to the UPF0212 family K09731 - - 0.000000000000000000000000000000000000002346 149.0
WH3_k127_3950663_2 Putative diguanylate phosphodiesterase - - - 0.000000000000002163 89.0
WH3_k127_3996742_0 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000000000000000001409 215.0
WH3_k127_3996742_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000004459 133.0
WH3_k127_3996742_2 general stress protein B in uncultured methanogenic archaeon (Q0W564) - - - 0.0000000000002435 72.0
WH3_k127_4073286_0 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000002386 226.0
WH3_k127_4073286_1 Periplasmic binding protein K02016 - - 0.00000000000000000000000000005721 126.0
WH3_k127_4073286_2 Periplasmic binding protein K02016 - - 0.00000000000000004855 86.0
WH3_k127_4073286_3 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.0000001244 57.0
WH3_k127_4100689_0 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 400.0
WH3_k127_4119470_0 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000005656 173.0
WH3_k127_4119470_1 Acylphosphatase K01512 - 3.6.1.7 0.00000000001335 74.0
WH3_k127_4119470_2 domain, Protein - - - 0.0000003202 63.0
WH3_k127_4119470_3 hydrolase (metallo-beta-lactamase superfamily) K02238 - - 0.00000121 56.0
WH3_k127_4132989_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 2.355e-294 918.0
WH3_k127_4132989_1 Ion channel - - - 0.000000002418 70.0
WH3_k127_4138920_0 Segregation and condensation complex subunit ScpB K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000258 236.0
WH3_k127_4138920_1 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000002164 162.0
WH3_k127_4138920_2 Domain of unknown function (DUF4258) - - - 0.0000000000000000000000000000000000000000222 154.0
WH3_k127_4138920_3 - - - - 0.00000000000000000000000000000006349 127.0
WH3_k127_4138920_4 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000003659 107.0
WH3_k127_4138920_5 mRNA binding - - - 0.000000000000000009535 85.0
WH3_k127_4138920_6 - - - - 0.00000000000034 73.0
WH3_k127_4138920_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000003744 57.0
WH3_k127_4201052_0 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 533.0
WH3_k127_4201052_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 516.0
WH3_k127_4201052_2 Helix-turn-helix domain protein K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004811 256.0
WH3_k127_4259941_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 537.0
WH3_k127_4299693_0 - - - - 0.00000000000000000000000000000000000000000000001512 182.0
WH3_k127_4299693_1 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000000000001803 144.0
WH3_k127_4299693_2 Transposase, IS605 OrfB family - - - 0.0000000001017 64.0
WH3_k127_4299693_3 Has ATPase and non-specific DNA-binding activities K07456 - - 0.00004313 48.0
WH3_k127_4414506_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 575.0
WH3_k127_4414506_1 Glycogen debranching enzyme N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 529.0
WH3_k127_4414506_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 298.0
WH3_k127_4414506_11 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000000000000000000000000002787 192.0
WH3_k127_4414506_12 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000000000000000001179 137.0
WH3_k127_4414506_2 PFAM Cation K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 434.0
WH3_k127_4414506_3 PFAM Radical SAM domain protein K02585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 406.0
WH3_k127_4414506_4 AAA domain (Cdc48 subfamily) K07392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 406.0
WH3_k127_4414506_5 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009678 399.0
WH3_k127_4414506_6 SMART Elongator protein 3 MiaB NifB K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 357.0
WH3_k127_4414506_7 cellular potassium ion transport K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 355.0
WH3_k127_4414506_8 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 338.0
WH3_k127_4414506_9 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 314.0
WH3_k127_4447290_0 PFAM N-6 DNA methylase K03427 - 2.1.1.72 8.919e-237 743.0
WH3_k127_4447290_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 317.0
WH3_k127_4447290_2 Type I restriction modification DNA specificity domain K01154,K03427 - 2.1.1.72,3.1.21.3 0.0000000000000000000000000000000000000000000000002024 183.0
WH3_k127_4451478_0 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 518.0
WH3_k127_4451478_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 349.0
WH3_k127_4451478_2 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000007068 245.0
WH3_k127_4459522_0 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 413.0
WH3_k127_4459522_1 AIR carboxylase K06898 - - 0.0000000000006652 74.0
WH3_k127_4483371_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 3.214e-230 725.0
WH3_k127_4483371_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 348.0
WH3_k127_4483371_2 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000000006789 207.0
WH3_k127_4509504_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.336e-237 747.0
WH3_k127_4509504_1 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 357.0
WH3_k127_4509504_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000008925 268.0
WH3_k127_4509504_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000156 150.0
WH3_k127_4518941_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 520.0
WH3_k127_4518941_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 451.0
WH3_k127_4518941_2 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 316.0
WH3_k127_4518941_3 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000001714 195.0
WH3_k127_4529154_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 327.0
WH3_k127_4529154_1 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000003622 155.0
WH3_k127_4529154_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000004233 123.0
WH3_k127_4563452_0 Protein of unknown function (DUF1016) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 435.0
WH3_k127_4563452_1 Reverse transcriptase-like K03469 - 3.1.26.4 0.000000000000000000000000001354 118.0
WH3_k127_4563452_2 DNA polymerase beta domain protein region - - - 0.00000000000004248 79.0
WH3_k127_4563452_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000006735 53.0
WH3_k127_4564791_0 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 385.0
WH3_k127_4564791_1 Elongator protein 3 MiaB NifB - - - 0.0000000000000000003987 88.0
WH3_k127_4564791_2 - - - - 0.0000000000000002271 83.0
WH3_k127_4564791_3 - - - - 0.0000000548 59.0
WH3_k127_4599361_0 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 321.0
WH3_k127_4599361_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000004545 230.0
WH3_k127_4612794_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 527.0
WH3_k127_4612794_1 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 449.0
WH3_k127_4612794_2 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 300.0
WH3_k127_4612794_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00008702 45.0
WH3_k127_4647259_0 Fructose-bisphosphate aldolase class-II - - - 1.707e-215 677.0
WH3_k127_4647259_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.348e-203 641.0
WH3_k127_4647259_10 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 310.0
WH3_k127_4647259_11 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 307.0
WH3_k127_4647259_12 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 301.0
WH3_k127_4647259_13 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 309.0
WH3_k127_4647259_14 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 295.0
WH3_k127_4647259_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 300.0
WH3_k127_4647259_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 296.0
WH3_k127_4647259_17 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 299.0
WH3_k127_4647259_18 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003458 252.0
WH3_k127_4647259_19 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000005051 237.0
WH3_k127_4647259_2 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 3.12e-202 637.0
WH3_k127_4647259_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000003874 224.0
WH3_k127_4647259_21 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000001352 218.0
WH3_k127_4647259_22 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000002183 202.0
WH3_k127_4647259_23 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000008655 197.0
WH3_k127_4647259_24 Bacterio-opsin activator HTH K06930,K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000001361 167.0
WH3_k127_4647259_25 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000001051 115.0
WH3_k127_4647259_26 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000003453 114.0
WH3_k127_4647259_27 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000000004665 109.0
WH3_k127_4647259_28 - - - - 0.000000000000000000000002156 107.0
WH3_k127_4647259_29 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000006252 91.0
WH3_k127_4647259_3 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 584.0
WH3_k127_4647259_30 ATP synthase subunit C K02124 - - 0.0000000000000000003664 89.0
WH3_k127_4647259_31 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000000007296 87.0
WH3_k127_4647259_32 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.0000000000001594 82.0
WH3_k127_4647259_33 - - - - 0.0000000000009391 77.0
WH3_k127_4647259_35 H subunit K02107 - - 0.00000000002762 68.0
WH3_k127_4647259_36 - - - - 0.0000000002226 66.0
WH3_k127_4647259_37 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000001915 61.0
WH3_k127_4647259_38 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.00000006349 57.0
WH3_k127_4647259_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 479.0
WH3_k127_4647259_5 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 409.0
WH3_k127_4647259_6 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 396.0
WH3_k127_4647259_7 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 377.0
WH3_k127_4647259_8 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 369.0
WH3_k127_4647259_9 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 381.0
WH3_k127_469827_0 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001411 289.0
WH3_k127_469827_1 - - - - 0.000000000000000000002281 108.0
WH3_k127_469827_2 - - - - 0.00000000000000000003219 101.0
WH3_k127_469827_3 - - - - 0.00000000000000008686 94.0
WH3_k127_469827_4 - - - - 0.00001253 55.0
WH3_k127_4703627_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 510.0
WH3_k127_4703627_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 432.0
WH3_k127_4703627_2 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 314.0
WH3_k127_4703627_3 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 310.0
WH3_k127_4703627_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002181 275.0
WH3_k127_4703627_5 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000001383 242.0
WH3_k127_4703627_6 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000001998 210.0
WH3_k127_4703627_7 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02009 - - 0.000000000000000000000000000717 124.0
WH3_k127_4703627_8 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000189 89.0
WH3_k127_4703627_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000001151 65.0
WH3_k127_4704924_0 glutamate decarboxylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 454.0
WH3_k127_4704924_1 RibD C-terminal domain K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000000000000009401 220.0
WH3_k127_4704924_2 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000003555 229.0
WH3_k127_4704924_3 - - - - 0.00000000000000000000003818 99.0
WH3_k127_4704924_4 - - - - 0.000000001336 62.0
WH3_k127_4860908_0 PFAM formate nitrite transporter K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 445.0
WH3_k127_4860908_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 401.0
WH3_k127_4860908_2 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000000000000003204 178.0
WH3_k127_4860908_3 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.00000000000000002839 82.0
WH3_k127_4994955_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000081 259.0
WH3_k127_4994955_1 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.000000000000000000000001627 109.0
WH3_k127_4994955_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000001896 98.0
WH3_k127_4994955_3 B12 binding domain - - - 0.0000000000000000001931 94.0
WH3_k127_4994955_4 PFAM Uncharacterised BCR, COG1649 - - - 0.0003117 55.0
WH3_k127_5008427_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 327.0
WH3_k127_5008427_1 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000000000000000000000000000000000009121 189.0
WH3_k127_5008427_2 PFAM TM2 domain containing protein - - - 0.0009916 48.0
WH3_k127_5017228_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 5.304e-261 819.0
WH3_k127_5017228_1 Probable transposase K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003078 273.0
WH3_k127_50343_0 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002136 265.0
WH3_k127_50343_1 Domain of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001842 252.0
WH3_k127_50343_2 Fumarase C-terminus K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000001015 185.0
WH3_k127_50343_3 Protein of unknown function (DUF434) - - - 0.00000000000000000000000000000000005523 144.0
WH3_k127_5044733_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 8.825e-240 746.0
WH3_k127_5044733_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 585.0
WH3_k127_5044733_2 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000002312 218.0
WH3_k127_5044733_3 Na -dependent transporter K03453 - - 0.00000000000000000000000000000000000008536 153.0
WH3_k127_5044733_4 Stage II sporulation protein M K06384 - - 0.0000000000000000000000000000000233 133.0
WH3_k127_5080681_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 0.00000000000000000000000000000003133 136.0
WH3_k127_5080681_1 by modhmm - - - 0.000000000000000003227 89.0
WH3_k127_5083982_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 602.0
WH3_k127_5083982_1 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 596.0
WH3_k127_5083982_10 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004695 261.0
WH3_k127_5083982_11 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007347 256.0
WH3_k127_5083982_12 archaeal coiled-coil protein - - - 0.000000000000000000000000000000000000000000000000001835 189.0
WH3_k127_5083982_13 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000000000000000007291 125.0
WH3_k127_5083982_14 nucleic acid binding OB-fold tRNA helicase-type - - - 0.000000000003152 71.0
WH3_k127_5083982_15 Phytol kinase K15892,K18678 - 2.7.1.182,2.7.1.216 0.000000004764 67.0
WH3_k127_5083982_16 PFAM Band 7 protein - - - 0.000001741 53.0
WH3_k127_5083982_17 F420H2 dehydrogenase subunit FpoO K22170 - 1.5.98.3 0.000004848 55.0
WH3_k127_5083982_18 Laminin-type epidermal growth factor-like domai K06240 GO:0001704,GO:0001706,GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0005604,GO:0005605,GO:0005608,GO:0005610,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005911,GO:0005912,GO:0005913,GO:0007044,GO:0007155,GO:0007275,GO:0007369,GO:0007492,GO:0008150,GO:0008544,GO:0009653,GO:0009790,GO:0009888,GO:0009987,GO:0012505,GO:0016043,GO:0022607,GO:0022610,GO:0030054,GO:0030055,GO:0030056,GO:0030154,GO:0030198,GO:0031012,GO:0031581,GO:0032501,GO:0032502,GO:0032991,GO:0034329,GO:0034330,GO:0035987,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043256,GO:0044085,GO:0044420,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0048598,GO:0048646,GO:0048856,GO:0048869,GO:0062023,GO:0070161,GO:0071840,GO:0098609 - 0.000005028 58.0
WH3_k127_5083982_2 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 582.0
WH3_k127_5083982_3 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 557.0
WH3_k127_5083982_4 PFAM major facilitator superfamily MFS_1 K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 531.0
WH3_k127_5083982_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 487.0
WH3_k127_5083982_6 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 353.0
WH3_k127_5083982_7 FmdE, Molybdenum formylmethanofuran dehydrogenase operon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 295.0
WH3_k127_5083982_8 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001989 271.0
WH3_k127_5083982_9 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007065 259.0
WH3_k127_5117725_0 Protein of unknown function, DUF255 K06888 - - 9.623e-243 769.0
WH3_k127_5117725_1 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 421.0
WH3_k127_5117725_2 PFAM glutamate--cysteine ligase, GCS2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 406.0
WH3_k127_5117725_3 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 368.0
WH3_k127_5117725_4 GPR1 FUN34 yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002721 277.0
WH3_k127_5117725_5 RimK-like ATPgrasp N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000003283 216.0
WH3_k127_5117725_6 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000004468 152.0
WH3_k127_5117725_7 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000001795 146.0
WH3_k127_5132283_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 3.81e-222 702.0
WH3_k127_5132283_1 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 336.0
WH3_k127_5132283_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 287.0
WH3_k127_5132283_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000001945 127.0
WH3_k127_5132283_4 PFAM phosphatidate cytidylyltransferase - - - 0.000000000193 70.0
WH3_k127_51344_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 332.0
WH3_k127_51344_1 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 316.0
WH3_k127_51344_2 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000001879 233.0
WH3_k127_51344_3 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.000000000000000000000000000000000000006112 149.0
WH3_k127_519566_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 3.718e-258 801.0
WH3_k127_519566_1 TIGRFAM Drug resistance transporter Bcr CflA subfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 486.0
WH3_k127_519566_10 PFAM PRC-barrel domain - - - 0.00000000000000000000746 94.0
WH3_k127_519566_11 - - - - 0.0000000003225 70.0
WH3_k127_519566_12 - - - - 0.000000003118 68.0
WH3_k127_519566_13 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000002055 54.0
WH3_k127_519566_2 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 440.0
WH3_k127_519566_3 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 425.0
WH3_k127_519566_4 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 360.0
WH3_k127_519566_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 342.0
WH3_k127_519566_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001767 254.0
WH3_k127_519566_7 tRNAHis guanylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000002331 216.0
WH3_k127_519566_8 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000001242 212.0
WH3_k127_519566_9 PDGLE domain K02007,K02009 - - 0.00000000000000000000000000000000000000003625 153.0
WH3_k127_5217723_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.852e-308 956.0
WH3_k127_5217723_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 2.861e-208 672.0
WH3_k127_5217723_10 Transglutaminase-like superfamily - - - 0.0000000003111 72.0
WH3_k127_5217723_11 nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000009651 52.0
WH3_k127_5217723_2 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 485.0
WH3_k127_5217723_3 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 430.0
WH3_k127_5217723_4 cytidyltransferase-related domain K00952 - 2.7.7.1 0.000000000000000000000000000000000000000000000000000000001111 206.0
WH3_k127_5217723_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000001522 203.0
WH3_k127_5217723_6 Belongs to the UPF0200 family - - - 0.0000000000000000000000000000000000000002675 156.0
WH3_k127_5217723_7 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.000000000000000000000000000000009105 138.0
WH3_k127_5217723_8 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.0000000000000000000000000000001612 138.0
WH3_k127_5217723_9 PFAM DNA polymerase, beta domain protein region K07075 - - 0.000000000006809 69.0
WH3_k127_5256030_0 PFAM oxidoreductase nitrogenase, component 1 K02591 - 1.18.6.1 4.126e-231 720.0
WH3_k127_5256030_1 Belongs to the NifD NifK NifE NifN family K02587 - - 6.904e-196 621.0
WH3_k127_5256030_2 Ammonium Transporter Family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 524.0
WH3_k127_5256030_3 Belongs to the NifD NifK NifE NifN family K02592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 447.0
WH3_k127_5256030_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 334.0
WH3_k127_5256030_5 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 312.0
WH3_k127_5256030_6 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 302.0
WH3_k127_5256030_7 ATPases associated with a variety of cellular activities K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000001687 243.0
WH3_k127_5256030_8 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000001202 158.0
WH3_k127_5256030_9 S-layer protein - - - 0.000000000000000721 92.0
WH3_k127_5446894_0 Domain of unknown function (DUF4198) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002629 239.0
WH3_k127_5446894_1 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000002907 160.0
WH3_k127_546605_0 helicase activity - - - 1.531e-229 738.0
WH3_k127_546605_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009801 340.0
WH3_k127_546605_2 - - - - 0.000000000000000000000000144 109.0
WH3_k127_546605_3 mRNA binding - - - 0.00000000000000003311 83.0
WH3_k127_546605_4 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000002168 81.0
WH3_k127_546605_5 mRNA binding - - - 0.000000000000001142 78.0
WH3_k127_546605_6 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000003003 78.0
WH3_k127_546605_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000004594 71.0
WH3_k127_546605_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000003124 58.0
WH3_k127_546605_9 Protein of unknown function DUF104 - - - 0.00004024 51.0
WH3_k127_5471429_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 394.0
WH3_k127_5471429_1 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 334.0
WH3_k127_5471429_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001125 278.0
WH3_k127_5471429_3 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004077 279.0
WH3_k127_5471429_4 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000000000001353 229.0
WH3_k127_5471429_5 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000007138 174.0
WH3_k127_5490106_0 ABC 3 transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 385.0
WH3_k127_5490106_1 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 290.0
WH3_k127_5490106_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000006294 224.0
WH3_k127_5490106_3 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000001323 209.0
WH3_k127_5490106_4 PFAM Methyltransferase type - - - 0.000000000000000000000000000000000000000001193 168.0
WH3_k127_5490106_5 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000003762 136.0
WH3_k127_5494410_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 336.0
WH3_k127_5494410_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 329.0
WH3_k127_5494410_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000007751 183.0
WH3_k127_5494410_3 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000006103 159.0
WH3_k127_5494410_4 metal ion binding - - - 0.0000000000000000000000003325 110.0
WH3_k127_5494410_5 Belongs to the UPF0235 family K09131 - - 0.0000000000000000001643 92.0
WH3_k127_5494410_6 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.000000000000000001778 99.0
WH3_k127_5494410_7 Probable transposase K07496 - - 0.0000000000007093 69.0
WH3_k127_5494410_8 TIGRFAM transposase, IS605 OrfB family K07496 - - 0.000000000433 63.0
WH3_k127_5494587_0 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000001392 227.0
WH3_k127_5494587_1 Probable transposase K07496 - - 0.0000000000003753 70.0
WH3_k127_5494587_3 cellulose binding K08604,K12132 - 2.7.11.1,3.4.24.25 0.0000139 57.0
WH3_k127_5494587_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00003086 51.0
WH3_k127_5516332_0 Belongs to the MCM family K10726 - - 3.122e-257 811.0
WH3_k127_5516332_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 586.0
WH3_k127_5516332_10 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000003596 94.0
WH3_k127_5516332_11 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000009195 90.0
WH3_k127_5516332_12 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000004103 81.0
WH3_k127_5516332_13 pfam nmd3 K07562 - - 0.00000000000000004439 86.0
WH3_k127_5516332_14 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000002872 78.0
WH3_k127_5516332_15 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000002954 62.0
WH3_k127_5516332_2 Clp protease K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 390.0
WH3_k127_5516332_3 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 335.0
WH3_k127_5516332_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002091 287.0
WH3_k127_5516332_5 Probable transposase K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007927 272.0
WH3_k127_5516332_6 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000001057 244.0
WH3_k127_5516332_7 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000000000000000000156 150.0
WH3_k127_5516332_8 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000000000001449 106.0
WH3_k127_5516332_9 Large family of predicted nucleotide-binding domains K07158 - - 0.000000000000000000000007303 105.0
WH3_k127_5542264_0 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 577.0
WH3_k127_5542264_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 398.0
WH3_k127_5542264_2 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000001047 162.0
WH3_k127_5542264_3 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000004811 154.0
WH3_k127_5542264_4 PFAM ribosomal protein S8E K02995 - - 0.000000000000000000000000000000000000002267 149.0
WH3_k127_5542264_5 TIGRFAM transposase, IS605 OrfB family K07496 - - 0.0000000000000000000000001621 109.0
WH3_k127_5542264_6 Calcineurin-like phosphoesterase - - - 0.0000000001376 72.0
WH3_k127_5542264_7 Domain of unknown function (DUF1922) - - - 0.0000005713 53.0
WH3_k127_5563890_0 C-terminal region of MMR_HSR1 domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009879 430.0
WH3_k127_5563890_1 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001591 269.0
WH3_k127_5563890_2 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000000000000000000000000000000001564 190.0
WH3_k127_5563890_3 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000000000000007281 128.0
WH3_k127_5563890_4 - - - - 0.0000000000000000000000002503 115.0
WH3_k127_5563890_5 - K00960 - 2.7.7.6 0.000000000000002014 77.0
WH3_k127_5563890_6 Putative phage serine protease XkdF - - - 0.000000000005243 72.0
WH3_k127_5654175_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 4.097e-223 700.0
WH3_k127_5654175_1 Belongs to the RtcB family K14415 - 6.5.1.3 9.563e-208 655.0
WH3_k127_5654175_10 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00000000000000000000000005523 111.0
WH3_k127_5654175_11 4Fe-4S binding domain - - - 0.000000000001224 68.0
WH3_k127_5654175_12 - - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - 0.000008844 51.0
WH3_k127_5654175_2 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 368.0
WH3_k127_5654175_3 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 363.0
WH3_k127_5654175_4 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 283.0
WH3_k127_5654175_5 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000000000000000000000000000004205 241.0
WH3_k127_5654175_6 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000005752 234.0
WH3_k127_5654175_7 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000001016 213.0
WH3_k127_5654175_8 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000000007438 172.0
WH3_k127_5654175_9 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000000001197 119.0
WH3_k127_5760658_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000009608 191.0
WH3_k127_5760658_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000007539 168.0
WH3_k127_5762991_0 CobN/Magnesium Chelatase K02230 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 497.0
WH3_k127_5767547_0 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000007097 199.0
WH3_k127_5810994_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 5.068e-201 637.0
WH3_k127_5810994_1 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 507.0
WH3_k127_5810994_2 DNA polymerase beta domain protein region K09717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 366.0
WH3_k127_5810994_3 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002135 243.0
WH3_k127_5810994_4 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000377 198.0
WH3_k127_5810994_5 Helix-turn-helix XRE-family like proteins K03627 - - 0.00000000000000000000000000000000000003791 148.0
WH3_k127_5867238_0 trans-aconitate 2-methyltransferase activity K00598,K02169 - 2.1.1.144,2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 298.0
WH3_k127_5867238_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000001567 188.0
WH3_k127_5867238_2 Transposase - - - 0.0000004722 51.0
WH3_k127_5874339_0 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 400.0
WH3_k127_5874339_1 COG0733 Na -dependent transporters of the SNF family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 360.0
WH3_k127_5874339_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002528 237.0
WH3_k127_5874339_3 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000001214 200.0
WH3_k127_5874339_4 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000000000001018 188.0
WH3_k127_5874339_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000001038 156.0
WH3_k127_5939239_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 461.0
WH3_k127_5944065_0 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 376.0
WH3_k127_5944065_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 346.0
WH3_k127_5944065_2 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 300.0
WH3_k127_5944065_3 Belongs to the UPF0285 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001282 271.0
WH3_k127_5944065_4 ZPR1-related zinc finger protein K06874 - - 0.000000000000000000000000000000000000000000000000002498 188.0
WH3_k127_5944065_5 Belongs to the UPF0179 family K09730 - - 0.000000000000000000000000000000000000000002601 159.0
WH3_k127_5944065_6 Pfam:DUF552 K09152 - - 0.000000000000000000000000001969 115.0
WH3_k127_5944065_7 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00583 - 2.1.1.86 0.0000000000181 67.0
WH3_k127_5944065_8 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.000000003096 67.0
WH3_k127_5944065_9 TIGRFAM tetrahydromethanopterin S-methyltransferase, F subunit K00582 - 2.1.1.86 0.0000001658 55.0
WH3_k127_5956746_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 346.0
WH3_k127_5956746_1 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 288.0
WH3_k127_5956746_2 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002391 248.0
WH3_k127_5956746_3 Uncharacterized protein conserved in archaea (DUF2209) - - - 0.0000000000000000000000000004836 117.0
WH3_k127_5956746_4 PFAM Radical SAM domain protein K02585 - - 0.00000000000000000000000000575 111.0
WH3_k127_5956746_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000000000006831 88.0
WH3_k127_595790_0 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 481.0
WH3_k127_595790_1 Probable transposase K07496 - - 0.000000000000004616 76.0
WH3_k127_595790_2 Transposase - - - 0.000000003542 58.0
WH3_k127_6037667_0 Belongs to the NifD NifK NifE NifN family K02587 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 327.0
WH3_k127_6037667_1 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000001198 64.0
WH3_k127_6037780_0 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 507.0
WH3_k127_6037780_1 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 307.0
WH3_k127_6069258_0 Heat shock 70 kDa protein K04043 - - 6.473e-261 817.0
WH3_k127_6069258_1 Belongs to the TCP-1 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 564.0
WH3_k127_6069258_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000002258 115.0
WH3_k127_6069258_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000009805 97.0
WH3_k127_6069258_12 PKD domain - - - 0.0008004 51.0
WH3_k127_6069258_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 407.0
WH3_k127_6069258_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 376.0
WH3_k127_6069258_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000007168 244.0
WH3_k127_6069258_5 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.00000000000000000000000000000000000000000000000000000000000000000001392 237.0
WH3_k127_6069258_6 Phosphate uptake regulator - - - 0.000000000000000000000000000000000000000000000000000363 197.0
WH3_k127_6069258_7 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000001512 172.0
WH3_k127_6069258_8 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000005845 156.0
WH3_k127_6069258_9 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000001355 147.0
WH3_k127_6130786_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 6.557e-319 987.0
WH3_k127_6130786_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 6.393e-220 687.0
WH3_k127_6130786_2 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 607.0
WH3_k127_6130786_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 436.0
WH3_k127_6130786_4 Belongs to the thymidylate synthase family. Archaeal- type ThyA subfamily K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 288.0
WH3_k127_6130786_5 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000006899 182.0
WH3_k127_6130786_6 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000004719 181.0
WH3_k127_6130786_7 Belongs to the GbsR family K22109 - - 0.0000000000009782 75.0
WH3_k127_6130786_8 Ion channel - - - 0.00000006816 64.0
WH3_k127_6148273_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 411.0
WH3_k127_6148273_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 359.0
WH3_k127_6148273_10 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.000000000000000000000004867 105.0
WH3_k127_6148273_11 Domain of unknown function (DUF1805) - - - 0.00000000000000000000007344 101.0
WH3_k127_6148273_12 COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000003294 93.0
WH3_k127_6148273_13 Belongs to the PDCD5 family K06875 - - 0.00000000000000001749 83.0
WH3_k127_6148273_14 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000001618 82.0
WH3_k127_6148273_15 structural constituent of ribosome K02924 - - 0.00000000000006565 72.0
WH3_k127_6148273_16 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.00000000004359 64.0
WH3_k127_6148273_2 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 355.0
WH3_k127_6148273_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 325.0
WH3_k127_6148273_4 Superoxide dismutase K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 295.0
WH3_k127_6148273_5 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000000000000000000000000000000000000000000000004909 224.0
WH3_k127_6148273_6 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000001449 202.0
WH3_k127_6148273_7 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.0000000000000000000000000000000000000000000000000104 188.0
WH3_k127_6148273_8 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000006578 165.0
WH3_k127_6148273_9 Ferric uptake regulator, Fur family K03711,K09825 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141 - 0.000000000000000000000000002647 117.0
WH3_k127_6149845_0 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 298.0
WH3_k127_6149845_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000703 246.0
WH3_k127_6149845_2 Ku70 and Ku80 are 70kDa and 80kDa subunits of the Lupus Ku autoantigen K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000001961 172.0
WH3_k127_6149845_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.000000000000000000000000000000005929 133.0
WH3_k127_6149845_4 PKD domain - - - 0.00000009327 64.0
WH3_k127_6165536_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 1.397e-302 940.0
WH3_k127_6165536_1 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 1.513e-274 856.0
WH3_k127_6165536_10 Domain of unknown function (DUF1894) - - - 0.00000000000000000000000000000000002225 139.0
WH3_k127_6165536_11 Molybdopterin converting factor K03635 - 2.8.1.12 0.0000000000000000000000000000000004624 134.0
WH3_k127_6165536_12 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000003347 112.0
WH3_k127_6165536_13 - - - - 0.0000000000000000000002307 100.0
WH3_k127_6165536_14 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000004039 76.0
WH3_k127_6165536_15 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.00000698 50.0
WH3_k127_6165536_2 4Fe-4S double cluster binding domain K00205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 453.0
WH3_k127_6165536_3 GXGXG motif K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 315.0
WH3_k127_6165536_4 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002976 281.0
WH3_k127_6165536_5 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001547 259.0
WH3_k127_6165536_6 Molybdopterin oxidoreductase K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000002866 189.0
WH3_k127_6165536_7 Domain of unknown function (DUF1890) - - - 0.0000000000000000000000000000000000000000000000000009464 187.0
WH3_k127_6165536_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000005321 188.0
WH3_k127_6165536_9 Molydopterin dinucleotide binding domain K00203 - 1.2.7.12 0.00000000000000000000000000000000000000000006277 168.0
WH3_k127_6196335_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 319.0
WH3_k127_6196335_1 signal transduction protein with CBS domains K07744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002133 281.0
WH3_k127_6196335_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000001512 213.0
WH3_k127_6215310_0 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 292.0
WH3_k127_6215310_1 Protein of unknown function (DUF1699) - - - 0.000000000000000000000000000000000000000004072 158.0
WH3_k127_6222583_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 497.0
WH3_k127_6222583_1 Serine dehydrogenase proteinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 354.0
WH3_k127_6222583_2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K02588,K21610 - 1.18.6.1,6.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 357.0
WH3_k127_6222583_3 S-layer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004036 288.0
WH3_k127_6222583_4 Rubrerythrin - - - 0.000000000000000000000000000000000000001084 149.0
WH3_k127_6222583_5 Transposase, is605 orfb family K07496 - - 0.0000000000000000000000000000001328 130.0
WH3_k127_6222583_6 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.000000000000000000000000007075 114.0
WH3_k127_6222583_7 PFAM Haemolysin-type calcium-binding repeat - - - 0.000000000000001375 87.0
WH3_k127_6222583_8 Transposase, is605 orfb family K07496 - - 0.00001436 49.0
WH3_k127_6222583_9 Domain of unknown function (DUF4430) - - - 0.0001952 50.0
WH3_k127_6239859_0 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 499.0
WH3_k127_6239859_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000002263 144.0
WH3_k127_6239859_2 Cysteine-rich small domain K08260 - 3.5.1.90 0.0000000000000000000000002455 117.0
WH3_k127_6262561_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 4.116e-310 966.0
WH3_k127_6262561_1 AAA family ATPase, CDC48 subfamily K13525 - - 1.588e-296 928.0
WH3_k127_6262561_10 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000579 236.0
WH3_k127_6262561_11 PFAM GvpD gas vesicle - - - 0.000000000000000000000000000000000000000000000000000000226 211.0
WH3_k127_6262561_12 methyltransferase activity K00577 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000132 188.0
WH3_k127_6262561_13 Catalyzes the insertion of Co(2 ) into sirohydrochlorin K02190 - 4.99.1.3 0.0000000000000000000000000000000000000000002531 170.0
WH3_k127_6262561_14 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000000009963 156.0
WH3_k127_6262561_15 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000002583 135.0
WH3_k127_6262561_16 PFAM regulatory protein, ArsR K07721 - - 0.00000000000000000000000000000003192 133.0
WH3_k127_6262561_17 - - - - 0.00000000000002505 78.0
WH3_k127_6262561_18 metallopeptidase activity - - - 0.0000000000005811 82.0
WH3_k127_6262561_19 Nuclease (SNase domain-containing protein) - - - 0.0000000000008175 78.0
WH3_k127_6262561_2 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.882e-275 861.0
WH3_k127_6262561_20 but it may be involved in stabilization of the trimeric complex - - - 0.00000000006374 66.0
WH3_k127_6262561_21 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0000000255 57.0
WH3_k127_6262561_22 - - - - 0.0000008791 57.0
WH3_k127_6262561_3 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 5.213e-268 843.0
WH3_k127_6262561_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.293e-238 754.0
WH3_k127_6262561_5 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 482.0
WH3_k127_6262561_6 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 476.0
WH3_k127_6262561_7 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 429.0
WH3_k127_6262561_8 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 350.0
WH3_k127_6262561_9 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 321.0
WH3_k127_62885_0 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 335.0
WH3_k127_62885_1 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000004158 175.0
WH3_k127_62885_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000024 168.0
WH3_k127_62885_3 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000009529 141.0
WH3_k127_62885_4 DNA integration - - - 0.0000000000000000000000000000003384 125.0
WH3_k127_62885_5 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000000000001562 126.0
WH3_k127_62885_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.000000000000000000000517 96.0
WH3_k127_62885_7 DNA integration - - - 0.0000000000003522 74.0
WH3_k127_6312570_0 COG1002 Type II restriction enzyme, methylase subunits - - - 1.755e-274 891.0
WH3_k127_6312570_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 3.283e-198 632.0
WH3_k127_6312570_2 PFAM ribonuclease II K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 518.0
WH3_k127_6312570_3 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 403.0
WH3_k127_6312570_4 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 300.0
WH3_k127_6312570_5 COG0668 Small-conductance mechanosensitive channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000178 248.0
WH3_k127_6312570_6 PFAM phosphoesterase, PA-phosphatase related K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000009391 243.0
WH3_k127_6312570_7 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000001436 184.0
WH3_k127_6312570_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000000007595 146.0
WH3_k127_6312570_9 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000003584 145.0
WH3_k127_6346470_0 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 3.795e-237 741.0
WH3_k127_6346470_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 2.994e-206 648.0
WH3_k127_6346470_2 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 589.0
WH3_k127_6346470_3 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 332.0
WH3_k127_6346470_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000002779 241.0
WH3_k127_6346470_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000000000000000000003564 94.0
WH3_k127_636402_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 3.325e-261 821.0
WH3_k127_636402_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 582.0
WH3_k127_636402_10 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000004261 220.0
WH3_k127_636402_11 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000002511 183.0
WH3_k127_636402_12 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000001889 144.0
WH3_k127_636402_13 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000001306 138.0
WH3_k127_636402_14 - - - - 0.000000000001965 71.0
WH3_k127_636402_15 COG1361 S-layer domain - - - 0.00000000006798 73.0
WH3_k127_636402_16 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000002974 61.0
WH3_k127_636402_2 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 476.0
WH3_k127_636402_3 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 422.0
WH3_k127_636402_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 314.0
WH3_k127_636402_5 ATPases associated with a variety of cellular activities K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 288.0
WH3_k127_636402_6 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003099 284.0
WH3_k127_636402_7 TIGRFAM F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006955 271.0
WH3_k127_636402_8 ABC-3 protein K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000633 248.0
WH3_k127_636402_9 ABC-type metal ion transport system periplasmic component surface adhesin K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003267 249.0
WH3_k127_6403117_0 COG0464 ATPases of the AAA class K13525 - - 2.607e-310 963.0
WH3_k127_6403117_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 571.0
WH3_k127_6403117_10 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 387.0
WH3_k127_6403117_11 PFAM transferase hexapeptide repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009413 266.0
WH3_k127_6403117_12 PFAM Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005396 258.0
WH3_k127_6403117_13 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000000000000000065 235.0
WH3_k127_6403117_14 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000008643 214.0
WH3_k127_6403117_15 PFAM Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000193 180.0
WH3_k127_6403117_16 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000001209 158.0
WH3_k127_6403117_17 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000006787 115.0
WH3_k127_6403117_18 Belongs to the UPF0146 family K09713 - - 0.000000000000000000000007433 106.0
WH3_k127_6403117_19 - - - - 0.0000000000004052 74.0
WH3_k127_6403117_2 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 515.0
WH3_k127_6403117_20 - - - - 0.000000457 55.0
WH3_k127_6403117_3 TIGRFAM UbiD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 464.0
WH3_k127_6403117_4 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 449.0
WH3_k127_6403117_5 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 426.0
WH3_k127_6403117_6 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 415.0
WH3_k127_6403117_7 NAD-dependent epimerase dehydratase K01709,K01710 - 4.2.1.45,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 406.0
WH3_k127_6403117_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 403.0
WH3_k127_6403117_9 involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 402.0
WH3_k127_6406302_0 Pfam Sulfatase K01130 - 3.1.6.1 1.773e-227 732.0
WH3_k127_6406302_1 Iron-sulfur cluster-binding domain K06871 - - 6.641e-196 618.0
WH3_k127_6406302_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 4.945e-194 615.0
WH3_k127_6406302_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005543 273.0
WH3_k127_6406302_4 Functions in trans to edit the amino acid moiety from K07050 GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000001339 225.0
WH3_k127_6406302_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000007682 183.0
WH3_k127_6406302_6 Glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.00000000000000000000000000000000000000000003374 165.0
WH3_k127_6406302_7 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000001008 102.0
WH3_k127_6406302_8 Probable transposase K07496 - - 0.00000000001922 65.0
WH3_k127_6406302_9 Protein of unknown function (DUF1016) - - - 0.00000817 51.0
WH3_k127_6422199_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 2.702e-239 750.0
WH3_k127_6422199_1 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 460.0
WH3_k127_6444382_0 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007898 261.0
WH3_k127_6444382_1 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000004936 220.0
WH3_k127_6444382_2 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.0000000000000000000000000000000000003334 152.0
WH3_k127_645779_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1680.0
WH3_k127_645779_1 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1420.0
WH3_k127_6458842_0 Putative Fe-S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001124 253.0
WH3_k127_6458842_1 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000000000000000000000000000001215 182.0
WH3_k127_6458842_2 protein involved in the oxidation of intracellular sulfur K07236 - - 0.000000000000000000000000000000000000000007927 156.0
WH3_k127_6458842_3 DsrH like protein K07237 - - 0.00000000000000000006869 92.0
WH3_k127_6514953_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 5.366e-222 703.0
WH3_k127_6514953_1 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 609.0
WH3_k127_6514953_10 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000006663 64.0
WH3_k127_6514953_11 PBS lyase HEAT-like repeat - - - 0.000007945 55.0
WH3_k127_6514953_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 435.0
WH3_k127_6514953_3 PFAM Radical SAM domain protein K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 349.0
WH3_k127_6514953_4 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 347.0
WH3_k127_6514953_5 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000002109 215.0
WH3_k127_6514953_6 SPTR Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000002856 203.0
WH3_k127_6514953_7 Protein of unknown function (DUF2551) - - - 0.0000000000000000000000000000000000002105 142.0
WH3_k127_6514953_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000002076 130.0
WH3_k127_6514953_9 Dodecin K09165 - - 0.0000000005131 65.0
WH3_k127_6547366_0 DEAD DEAH box helicase domain protein K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 519.0
WH3_k127_6547366_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 343.0
WH3_k127_6547366_10 - K00960 - 2.7.7.6 0.0000000000000005485 78.0
WH3_k127_6547366_11 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.000000000000001047 80.0
WH3_k127_6547366_12 COG2366 Protein related to penicillin acylase K01434 - 3.5.1.11 0.0000007448 53.0
WH3_k127_6547366_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 287.0
WH3_k127_6547366_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K22446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007338 270.0
WH3_k127_6547366_4 PFAM Leucine rich repeat variant - - - 0.000000000000000000000000000000000001012 149.0
WH3_k127_6547366_5 Transposase, is605 orfb family K07496 - - 0.0000000000000000000000000000003906 136.0
WH3_k127_6547366_6 eRF1 domain 2 - - - 0.000000000000000000000002458 114.0
WH3_k127_6547366_7 Pfam:Nol1_Nop2_Fmu_2 - - - 0.000000000000000000000003326 109.0
WH3_k127_6547366_8 Belongs to the UPF0248 family K09715 - - 0.000000000000000000169 91.0
WH3_k127_6547366_9 TRAM domain - - - 0.00000000000000001867 84.0
WH3_k127_6562171_0 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0 1201.0
WH3_k127_6562171_1 DNA methylase K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 327.0
WH3_k127_6562171_2 Tetratricopeptide TPR_2 repeat protein K07503 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005593 263.0
WH3_k127_6562171_3 protein N-acetylglucosaminyltransferase activity K12600 - - 0.00000000000000000000000000000000000000000000000000000000000002777 237.0
WH3_k127_6562171_4 cyclopropane-fatty-acyl-phospholipid synthase K00574,K15256,K15257 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000004845 195.0
WH3_k127_6573634_0 SMART Elongator protein 3 MiaB NifB - - - 1.324e-279 869.0
WH3_k127_6573634_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.625e-274 855.0
WH3_k127_6573634_10 - - - - 0.000000004402 59.0
WH3_k127_6573634_11 Protein of unknown function (DUF3795) - - - 0.0000008285 58.0
WH3_k127_6573634_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 372.0
WH3_k127_6573634_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004816 250.0
WH3_k127_6573634_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
WH3_k127_6573634_5 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000001956 171.0
WH3_k127_6573634_6 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K16305 GO:0003674,GO:0003824,GO:0004332,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016832 2.2.1.11,4.1.2.13 0.00000000000000000000000000000005782 125.0
WH3_k127_6573634_7 PFAM plasmid stabilization system - - - 0.000000000000000000000007736 103.0
WH3_k127_6573634_8 Psort location Periplasmic, score 9.44 K07218 - - 0.00000000000000000006439 103.0
WH3_k127_6573634_9 Belongs to the acylphosphatase family - - - 0.000000000001521 77.0
WH3_k127_6579283_0 PFAM Plasmid pRiA4b ORF-3-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001505 227.0
WH3_k127_6579283_1 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000002864 108.0
WH3_k127_6579283_2 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000001477 101.0
WH3_k127_6579283_3 Cache domain - - - 0.00000000000000000000008294 109.0
WH3_k127_6579283_4 PFAM YcfA-like protein - - - 0.00000000000000000008001 89.0
WH3_k127_6579283_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000002499 89.0
WH3_k127_6591312_0 Ferrous iron transport protein B C terminus K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 552.0
WH3_k127_6591312_1 - - - - 0.000000000000000000000000000000000000000000000007249 186.0
WH3_k127_6591312_2 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000000000000000000000007129 133.0
WH3_k127_6591312_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000004251 118.0
WH3_k127_6591312_4 Cyclophilin-like K09143 - - 0.0000000000000000000000116 103.0
WH3_k127_6591312_6 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000003659 88.0
WH3_k127_6591312_7 - - - - 0.00000000002586 73.0
WH3_k127_6591312_8 Probable transposase K07496 - - 0.00000004283 54.0
WH3_k127_6694496_0 TPR repeat - - - 1.842e-215 688.0
WH3_k127_6694496_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K22161 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 410.0
WH3_k127_6694496_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 346.0
WH3_k127_6694496_3 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 334.0
WH3_k127_6694496_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000001548 243.0
WH3_k127_6694496_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K22159 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000007343 238.0
WH3_k127_6694496_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000005433 117.0
WH3_k127_6694496_8 Amino acid permease K03294 - - 0.0000000000002376 73.0
WH3_k127_6694496_9 Predicted nucleotidyltransferase K07074 - - 0.0000005509 60.0
WH3_k127_6783295_0 - K19200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 424.0
WH3_k127_6783295_1 GrpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004182 275.0
WH3_k127_6783295_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000004343 236.0
WH3_k127_6783295_3 serine-type aminopeptidase activity K02030,K14475 - - 0.00000000000001022 83.0
WH3_k127_681445_0 Adenine specific DNA methylase Mod K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 308.0
WH3_k127_681445_1 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000009359 110.0
WH3_k127_681445_2 Protein conserved in bacteria K00013,K00942,K01154,K03933,K07316 - 1.1.1.23,2.1.1.72,2.7.4.8,3.1.21.3 0.0000000000000000004368 90.0
WH3_k127_681445_3 Protein of unknown function (DUF3800) - - - 0.00000000001005 73.0
WH3_k127_681445_4 addiction module toxin, RelE StbE family K19158 - - 0.0000000002458 66.0
WH3_k127_6840686_0 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000641 278.0
WH3_k127_6840686_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000000000001378 185.0
WH3_k127_6840686_2 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.000000000000000000002426 94.0
WH3_k127_6840686_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000003465 63.0
WH3_k127_6920129_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 571.0
WH3_k127_6920129_1 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000007528 252.0
WH3_k127_6920129_2 aconitate hydratase K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000001966 237.0
WH3_k127_6994168_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.505e-284 900.0
WH3_k127_6994168_1 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 429.0
WH3_k127_6994168_10 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000000000001298 80.0
WH3_k127_6994168_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 393.0
WH3_k127_6994168_3 acid binding OB-fold tRNA helicase-type K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 316.0
WH3_k127_6994168_4 Pfam:DUF137 K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 293.0
WH3_k127_6994168_5 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000457 237.0
WH3_k127_6994168_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000001917 231.0
WH3_k127_6994168_7 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000001167 185.0
WH3_k127_6994168_8 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000003584 156.0
WH3_k127_6994168_9 PFAM GHMP kinase K06982 - 2.7.1.169 0.0000000000000000000001212 100.0
WH3_k127_6995411_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 506.0
WH3_k127_6995411_1 aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 447.0
WH3_k127_6995411_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000164 130.0
WH3_k127_6995411_11 - - - - 0.000000000000000000000000000004438 127.0
WH3_k127_6995411_12 PFAM thioesterase superfamily K02614 - - 0.0000000000000000000000000000136 124.0
WH3_k127_6995411_13 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000007661 115.0
WH3_k127_6995411_14 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000001844 88.0
WH3_k127_6995411_15 Nodulation protein S (NodS) - - - 0.000000000000005948 84.0
WH3_k127_6995411_16 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000002175 61.0
WH3_k127_6995411_17 CHAT domain - - - 0.0001808 48.0
WH3_k127_6995411_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 389.0
WH3_k127_6995411_3 PFAM PP-loop - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 295.0
WH3_k127_6995411_4 Transposase domain (DUF772) K07481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 293.0
WH3_k127_6995411_5 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 285.0
WH3_k127_6995411_6 Functions by promoting the formation of the first peptide bond K03263 - - 0.0000000000000000000000000000000000000000000000001227 179.0
WH3_k127_6995411_7 TfuA-like protein - - - 0.00000000000000000000000000000000000003713 151.0
WH3_k127_6995411_8 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000008615 134.0
WH3_k127_6995411_9 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.00000000000000000000000000000001193 136.0
WH3_k127_7016297_0 snf2 family K08282 - 2.7.11.1 1.303e-207 675.0
WH3_k127_7016297_1 domain, Protein K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 534.0
WH3_k127_7016297_2 COG0471 Di- and tricarboxylate transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 514.0
WH3_k127_7016297_3 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000006772 234.0
WH3_k127_7016297_4 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000001497 225.0
WH3_k127_7016297_5 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000001736 183.0
WH3_k127_7016297_6 Transposase IS200 like K07491 - - 0.000000000000000000000174 96.0
WH3_k127_7035941_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 1.078e-279 881.0
WH3_k127_7035941_1 decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin K04720 - 4.1.1.81 0.0006317 43.0
WH3_k127_7041838_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008569 384.0
WH3_k127_7041838_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000008755 119.0
WH3_k127_7063459_0 Nitroreductase family - - - 0.000000000000000000000000000000000008657 143.0
WH3_k127_7063459_1 Met-10+ like-protein K15429 - 2.1.1.228 0.000000000000000000000000000005269 120.0
WH3_k127_7063459_2 haloacid dehalogenase-like hydrolase K01560,K07025 - 3.8.1.2 0.0000007867 57.0
WH3_k127_7074592_0 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000007281 186.0
WH3_k127_7074592_1 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000002922 103.0
WH3_k127_7074592_2 DJ-1/PfpI family - - - 0.0000000000000000002972 89.0
WH3_k127_7131420_0 Putative transposase DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 385.0
WH3_k127_7131420_1 PFAM NAD(P)H dehydrogenase (quinone) K00355 - 1.6.5.2 0.000000000000000000000000000000000000000004568 156.0
WH3_k127_7131420_2 PFAM Lon protease (S16) C-terminal proteolytic domain K06870 - - 0.000000000000000000000000004766 121.0
WH3_k127_7131420_3 PFAM TM2 domain containing protein K03686 - - 0.000000001617 61.0
WH3_k127_7131420_4 ubiE/COQ5 methyltransferase family - - - 0.0009869 44.0
WH3_k127_7165094_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 421.0
WH3_k127_7165094_1 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000269 276.0
WH3_k127_7165094_2 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000002442 138.0
WH3_k127_7165094_3 translation release factor activity K03265,K04043 GO:0000184,GO:0000956,GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003747,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006401,GO:0006402,GO:0006412,GO:0006415,GO:0006417,GO:0006449,GO:0006464,GO:0006479,GO:0006518,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007224,GO:0008022,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0008213,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009889,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010494,GO:0010556,GO:0010605,GO:0010608,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016149,GO:0018130,GO:0018444,GO:0019222,GO:0019438,GO:0019439,GO:0019538,GO:0022411,GO:0023052,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0032774,GO:0032984,GO:0032991,GO:0034248,GO:0034641,GO:0034645,GO:0034654,GO:0034655,GO:0035770,GO:0036211,GO:0036464,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051246,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990825,GO:1990904,GO:2000112 - 0.000000000001299 79.0
WH3_k127_7165094_4 Rubredoxin - - - 0.0000000006178 69.0
WH3_k127_720339_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 1.081e-289 912.0
WH3_k127_720339_1 - - - - 0.00000000000000000000001474 100.0
WH3_k127_720339_2 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000008151 95.0
WH3_k127_7290107_0 Uncharacterized protein conserved in archaea (DUF2193) - - - 4.07e-258 803.0
WH3_k127_7290107_1 TIGRFAM MIP family channel K02440,K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 363.0
WH3_k127_7290107_2 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.00000000000000000000000000000007049 125.0
WH3_k127_7290107_3 DGC domain - - - 0.000000000000000000000004903 106.0
WH3_k127_7290107_4 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.00000000000000000000001933 101.0
WH3_k127_7290107_5 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000001532 109.0
WH3_k127_7290107_6 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000001608 101.0
WH3_k127_7290107_7 Rhodanese Homology Domain K01011 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016782,GO:0016783,GO:0016784,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 2.8.1.1,2.8.1.2 0.00000000000001843 85.0
WH3_k127_7290107_8 Probable transposase K07496 - - 0.0000000000008923 68.0
WH3_k127_7290107_9 GtrA family K00721,K00786 - 2.4.1.83 0.00001236 54.0
WH3_k127_7291680_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 589.0
WH3_k127_7328202_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 588.0
WH3_k127_7328202_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 461.0
WH3_k127_7328202_10 Phosphomethylpyrimidine kinase K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000003047 55.0
WH3_k127_7328202_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 380.0
WH3_k127_7328202_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 344.0
WH3_k127_7328202_4 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 338.0
WH3_k127_7328202_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007179 280.0
WH3_k127_7328202_6 amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000001707 199.0
WH3_k127_7328202_7 Methanogenesis marker protein 8 - - - 0.00000000000000000000000000000000000000000000001122 179.0
WH3_k127_7328202_8 - - - - 0.0000000000000006731 84.0
WH3_k127_7328202_9 Belongs to the eukaryotic ribosomal protein eS17 family K02962 - - 0.0000000000001612 73.0
WH3_k127_7343276_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 461.0
WH3_k127_7343276_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 370.0
WH3_k127_7343276_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000002161 214.0
WH3_k127_7343276_3 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000001024 214.0
WH3_k127_7343276_4 Putative heavy-metal chelation - - - 0.000000000000000000000000000000000000000000000000000001393 201.0
WH3_k127_7343276_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000001836 186.0
WH3_k127_7343276_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000002579 166.0
WH3_k127_7343276_7 Nucleotidyltransferase domain - - - 0.000000000000000003072 87.0
WH3_k127_7431944_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 454.0
WH3_k127_7431944_1 Alternative locus ID - - - 0.00000000000000000000000000000000000000000000000000525 199.0
WH3_k127_7431944_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000001644 171.0
WH3_k127_7431944_3 PFAM GHMP kinase K06982 - 2.7.1.169 0.000001416 52.0
WH3_k127_7462826_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 560.0
WH3_k127_7462826_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 348.0
WH3_k127_7462826_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 313.0
WH3_k127_7462826_3 cheY-homologous receiver domain - - - 0.00000000000000000000000001823 113.0
WH3_k127_7462826_4 Pentapeptide repeats (9 copies) - - - 0.00000000002808 76.0
WH3_k127_7462826_5 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000002233 61.0
WH3_k127_7498937_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 445.0
WH3_k127_7498937_1 PFAM cobalamin synthesis protein P47K - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 373.0
WH3_k127_7498937_2 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 356.0
WH3_k127_7498937_3 glycerophosphoryl diester phosphodiesterase K01126 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 353.0
WH3_k127_7498937_4 PFAM Fe-S cluster domain protein K06939 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009745 246.0
WH3_k127_7498937_5 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000005074 209.0
WH3_k127_7504375_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 368.0
WH3_k127_7504375_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 331.0
WH3_k127_7504375_2 PFAM sigma-70 region 4 domain protein K09714 - - 0.000000000000000000000000006285 115.0
WH3_k127_7504375_3 Probable transposase K07496 - - 0.00000000000000000000000009721 108.0
WH3_k127_7534120_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1021.0
WH3_k127_7534120_1 PFAM multi antimicrobial extrusion protein MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 535.0
WH3_k127_7534120_2 Probable transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 432.0
WH3_k127_7534120_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 431.0
WH3_k127_7534120_4 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000001198 231.0
WH3_k127_7534120_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000001884 221.0
WH3_k127_7534120_6 archaeal Zn-finger protein - - - 0.00000000000000000000000001078 116.0
WH3_k127_7560647_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 379.0
WH3_k127_7560647_1 Cellulose biosynthesis protein BcsQ K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008924 258.0
WH3_k127_7560647_2 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15586 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001603 259.0
WH3_k127_7560647_3 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000001035 190.0
WH3_k127_7560647_4 Periplasmic binding protein K02016 - - 0.000000000000000000004123 107.0
WH3_k127_7560647_5 MFS/sugar transport protein - - - 0.000000000002031 69.0
WH3_k127_7560647_6 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000002229 80.0
WH3_k127_7560647_7 Predicted RNA-binding protein - - - 0.00000000002542 65.0
WH3_k127_7560647_8 Domain of unknown function (DUF4198) - - - 0.0002798 43.0
WH3_k127_7626130_0 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 570.0
WH3_k127_7626130_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 553.0
WH3_k127_7626130_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl- CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 553.0
WH3_k127_7626130_3 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 287.0
WH3_k127_7626130_4 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000001248 222.0
WH3_k127_7626130_5 COG0500 SAM-dependent methyltransferases K17462 - - 0.000000000000000000000000000000000000000000000000000001939 200.0
WH3_k127_7626130_6 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.00000000000000000000000000000000000000139 154.0
WH3_k127_7626130_7 Flavodoxin - - - 0.0000000000000000000000000005717 119.0
WH3_k127_7626130_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000002198 79.0
WH3_k127_7639030_0 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.000000000000000000000000000000000000000000000006876 181.0
WH3_k127_7639030_1 PFAM Major facilitator superfamily - - - 0.00000000000000000000000009198 109.0
WH3_k127_7639030_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000002008 85.0
WH3_k127_7639030_3 Belongs to the GbsR family K22109 - - 0.000000064 63.0
WH3_k127_7661830_0 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 318.0
WH3_k127_7661830_1 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 301.0
WH3_k127_7661830_2 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006778 274.0
WH3_k127_7661830_3 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000000000000000000000000000000002168 235.0
WH3_k127_7661830_4 Involved in cell shape control K22222 - - 0.000000000000000000000000000000000007241 138.0
WH3_k127_7661830_5 - - - - 0.00000000000002052 85.0
WH3_k127_7702755_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1314.0
WH3_k127_7702755_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 2.863e-240 747.0
WH3_k127_7702755_10 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000001454 207.0
WH3_k127_7702755_11 transcription termination protein NusA K02600 - - 0.00000000000000000000000000000000000000000000000000004821 190.0
WH3_k127_7702755_12 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.0000000000000000000000001296 111.0
WH3_k127_7702755_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 489.0
WH3_k127_7702755_3 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 383.0
WH3_k127_7702755_4 PFAM elongation factor Tu domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 383.0
WH3_k127_7702755_5 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 294.0
WH3_k127_7702755_6 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001372 256.0
WH3_k127_7702755_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000004423 233.0
WH3_k127_7702755_8 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000002013 241.0
WH3_k127_7702755_9 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.000000000000000000000000000000000000000000000000000000000000002285 219.0
WH3_k127_7710788_0 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008731 451.0
WH3_k127_7710788_1 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 414.0
WH3_k127_7710788_2 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007304 250.0
WH3_k127_7710788_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.000000000000000000000000000000000000000000000000000000003075 228.0
WH3_k127_7710788_4 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000006887 203.0
WH3_k127_7710788_5 Permease - - - 0.00000000000000000000000000000000000000000000001074 186.0
WH3_k127_7710788_6 NurA - - - 0.0000000000000000000000008723 116.0
WH3_k127_7710788_7 Belongs to the UPF0761 family K07058 - - 0.00000000000000000001244 104.0
WH3_k127_7841236_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.847e-289 914.0
WH3_k127_7841236_1 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 579.0
WH3_k127_7841236_10 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000001325 186.0
WH3_k127_7841236_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000001564 186.0
WH3_k127_7841236_12 Glutaredoxin - - - 0.0000000000000000000000000000000008518 132.0
WH3_k127_7841236_14 Cupin domain - - - 0.0000000000000000000000004238 108.0
WH3_k127_7841236_15 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000006392 99.0
WH3_k127_7841236_16 pfam yhs - - - 0.000000000000000007379 89.0
WH3_k127_7841236_17 - - - - 0.00000000004444 65.0
WH3_k127_7841236_18 Domain of unknown function (DUF4130 K21929 - 3.2.2.27 0.0001136 52.0
WH3_k127_7841236_19 - - - - 0.000447 42.0
WH3_k127_7841236_2 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 560.0
WH3_k127_7841236_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 532.0
WH3_k127_7841236_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 465.0
WH3_k127_7841236_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 457.0
WH3_k127_7841236_6 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 413.0
WH3_k127_7841236_7 DNA modification repair radical SAM protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 304.0
WH3_k127_7841236_8 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 283.0
WH3_k127_7841236_9 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000000000001011 214.0
WH3_k127_7895250_0 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000004549 213.0
WH3_k127_7895250_1 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000002111 188.0
WH3_k127_7895250_2 Periplasmic binding protein K02016 - - 0.00000001569 56.0
WH3_k127_7906419_0 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000006239 109.0
WH3_k127_7906419_1 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.00000000000000002367 85.0
WH3_k127_7906419_2 - - - - 0.000000001171 64.0
WH3_k127_7906419_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000001912 53.0
WH3_k127_7927671_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 2.355e-198 638.0
WH3_k127_7927671_1 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 610.0
WH3_k127_7927671_10 iron ion homeostasis K02015 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000001677 66.0
WH3_k127_7927671_11 PFAM ABC transporter related K01990 - - 0.00000005923 55.0
WH3_k127_7927671_12 ABC transporter, (ATP-binding protein) K06861 - - 0.0003504 43.0
WH3_k127_7927671_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 567.0
WH3_k127_7927671_3 ABC-type Fe3 -siderophore transport system, permease component K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 418.0
WH3_k127_7927671_4 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 400.0
WH3_k127_7927671_5 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 301.0
WH3_k127_7927671_6 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000007397 270.0
WH3_k127_7927671_7 alkylhydroperoxidase like protein, AhpD family - - - 0.0000000000000000000000000001372 117.0
WH3_k127_7927671_8 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000008845 124.0
WH3_k127_7927671_9 catalyzes the formation of a number of methylated intermediates from arsenite and SAM producing trimethylarsine K07755 - 2.1.1.137 0.000000000005401 76.0
WH3_k127_7931118_0 CoA binding domain - - - 7.577e-266 835.0
WH3_k127_7931118_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 4.923e-231 729.0
WH3_k127_7931118_10 ATP-grasp domain K06914 - 6.3.4.24 0.0000000000000000000000000000000000000000000000000000000000000006397 229.0
WH3_k127_7931118_11 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000003732 226.0
WH3_k127_7931118_12 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000008449 204.0
WH3_k127_7931118_13 PFAM Phosphatidylglycerophosphatase A - - - 0.000000000000000000000000000000000000000000000000000001577 197.0
WH3_k127_7931118_14 PFAM methyltransferase small K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000001541 188.0
WH3_k127_7931118_15 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000002287 188.0
WH3_k127_7931118_16 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000001532 186.0
WH3_k127_7931118_17 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001808 169.0
WH3_k127_7931118_18 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000003218 157.0
WH3_k127_7931118_19 Papain family cysteine protease - - - 0.000000000000000000000000000000000000003248 159.0
WH3_k127_7931118_2 PFAM chaperonin Cpn60 TCP-1 K22447 - - 1.539e-194 621.0
WH3_k127_7931118_20 Putative Fe-S cluster K11260 - - 0.0000000000000000000000000000000001432 135.0
WH3_k127_7931118_21 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000000000004809 122.0
WH3_k127_7931118_22 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000003572 130.0
WH3_k127_7931118_23 PFAM Like-Sm ribonucleoprotein, core - - - 0.00000000000000000000000002671 109.0
WH3_k127_7931118_24 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.0000000000000000000000003952 113.0
WH3_k127_7931118_25 Uncharacterized protein, homolog of nitrogen regulatory protein PII - - - 0.00000000000000000000003241 102.0
WH3_k127_7931118_26 B-block binding subunit of TFIIIC - - - 0.0000000000000000000002344 101.0
WH3_k127_7931118_27 Protein of unknown function (DUF473) K09135 - - 0.00000000000000000004066 94.0
WH3_k127_7931118_28 NifU-like domain - - - 0.000000000000000001075 87.0
WH3_k127_7931118_29 Binds to the 23S rRNA K02896 - - 0.00000000000000001143 85.0
WH3_k127_7931118_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 596.0
WH3_k127_7931118_30 - - - - 0.0000000000000000972 81.0
WH3_k127_7931118_31 Cold shock protein K03704 - - 0.0000000000001084 72.0
WH3_k127_7931118_32 - - - - 0.0000000000309 68.0
WH3_k127_7931118_33 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.00000000006371 72.0
WH3_k127_7931118_34 Gar1/Naf1 RNA binding region K07569 - - 0.0000000001038 65.0
WH3_k127_7931118_35 ATP-grasp domain K06914 - 6.3.4.24 0.0000000005149 61.0
WH3_k127_7931118_36 PLD-like domain - - - 0.000000001254 68.0
WH3_k127_7931118_37 - - - - 0.00000001423 65.0
WH3_k127_7931118_4 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 577.0
WH3_k127_7931118_5 PFAM dihydropteroate synthase, DHPS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 436.0
WH3_k127_7931118_6 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 442.0
WH3_k127_7931118_7 TIGRFAM small GTP-binding protein K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 352.0
WH3_k127_7931118_8 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 329.0
WH3_k127_7931118_9 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002095 265.0
WH3_k127_8003105_0 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 323.0
WH3_k127_8003105_1 Threonine synthase N terminus K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 301.0
WH3_k127_8003105_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 301.0
WH3_k127_8003105_3 PFAM UspA domain protein - - - 0.0000000000000000000000000000000007045 135.0
WH3_k127_8250259_0 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 462.0
WH3_k127_8250259_1 TIGRFAM archaeoflavoprotein AfpA - - - 0.00000000000000000000000000000000000000000000000000000000000000000002289 237.0
WH3_k127_8250259_2 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.00000000000000000000000000000000000000000000000000000000001222 222.0
WH3_k127_8250259_3 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000001592 134.0
WH3_k127_8250259_4 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.000000000000000000000000000005284 124.0
WH3_k127_8270229_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 5.561e-229 715.0
WH3_k127_8270229_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 396.0
WH3_k127_8270229_2 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 383.0
WH3_k127_8270229_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000002276 241.0
WH3_k127_8270229_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000236 172.0
WH3_k127_8276345_0 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 375.0
WH3_k127_8276345_1 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006807 286.0
WH3_k127_8276345_2 Belongs to the UPF0216 family K09737 - - 0.0000000000000221 79.0
WH3_k127_8299043_0 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 429.0
WH3_k127_8299043_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 395.0
WH3_k127_8299043_2 PFAM Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 339.0
WH3_k127_8299043_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000356 262.0
WH3_k127_8299043_4 Small Multidrug Resistance protein K03297 - - 0.00000000000000000000000000000000000007957 144.0
WH3_k127_8299043_5 Transposase - - - 0.0003133 43.0
WH3_k127_8379280_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 527.0
WH3_k127_8379280_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 314.0
WH3_k127_8379280_2 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000001099 143.0
WH3_k127_8379280_3 - - - - 0.000000001255 62.0
WH3_k127_8379280_4 addiction module toxin, RelE StbE family - - - 0.00000008941 58.0
WH3_k127_8389751_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 512.0
WH3_k127_8389751_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 343.0
WH3_k127_8389751_2 ATPases associated with a variety of cellular activities K00400 - - 0.000000000000000000000000000000000000000000000000000000000000002224 222.0
WH3_k127_8389751_3 Transposase - - - 0.000000003717 58.0
WH3_k127_8390169_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 496.0
WH3_k127_8390169_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 459.0
WH3_k127_8390169_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 400.0
WH3_k127_8390169_3 Transposase - - - 0.0000000007545 60.0
WH3_k127_8390169_4 spore germination K08978 - - 0.00000001285 66.0
WH3_k127_8512559_0 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 322.0
WH3_k127_8512559_1 Probable transposase K07496 - - 0.00000004283 54.0
WH3_k127_8668428_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 451.0
WH3_k127_8668428_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 441.0
WH3_k127_8688391_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 582.0
WH3_k127_8688391_1 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000003109 170.0
WH3_k127_8688391_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000003447 151.0
WH3_k127_8696619_0 PFAM ABC transporter K00400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 284.0
WH3_k127_8696619_1 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000125 272.0
WH3_k127_8696619_2 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000105 232.0
WH3_k127_8696619_3 Sodium:solute symporter family K03307 - - 0.000000000000000000000000000000000000000000000000001439 200.0
WH3_k127_8696619_4 Probable transposase K07496 - - 0.0000000000000000000000008672 105.0
WH3_k127_8696619_5 - - - - 0.000000000000003843 83.0
WH3_k127_8696619_6 positive regulation of translation, ncRNA-mediated K03666 - - 0.0003006 46.0
WH3_k127_8766995_0 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 3.461e-224 706.0
WH3_k127_8766995_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 518.0
WH3_k127_8766995_10 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000001598 71.0
WH3_k127_8766995_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004021 282.0
WH3_k127_8766995_3 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002735 281.0
WH3_k127_8766995_4 methyltransferase small K07579 - - 0.00000000000000000000000000000000000000000000000000000003067 202.0
WH3_k127_8766995_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000000000000009938 185.0
WH3_k127_8766995_6 RNA-binding protein of the translin family K07477 - - 0.00000000000000000000000000000000000000000000000001148 186.0
WH3_k127_8766995_7 adenyl ribonucleotide binding - - - 0.000000000000000000001019 102.0
WH3_k127_8766995_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000000000000001342 93.0
WH3_k127_8766995_9 COG0642 Signal transduction histidine kinase - - - 0.00000000000008339 85.0
WH3_k127_8851686_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 1.705e-243 767.0
WH3_k127_8851686_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 553.0
WH3_k127_8851686_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 391.0
WH3_k127_8851686_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001828 259.0
WH3_k127_8851686_4 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000005342 235.0
WH3_k127_8851686_5 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000271 191.0
WH3_k127_8851686_6 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000001389 104.0
WH3_k127_8851686_7 Belongs to the UPF0434 family - - - 0.00000000000000000000000375 102.0
WH3_k127_8851686_8 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.0001088 51.0
WH3_k127_8851686_9 - - - - 0.000745 51.0
WH3_k127_888021_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000009541 106.0
WH3_k127_8929240_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.695e-272 856.0
WH3_k127_8929240_1 PFAM Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 513.0
WH3_k127_8929240_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 380.0
WH3_k127_8929240_3 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000000000000000000000007124 182.0
WH3_k127_8929240_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000001038 149.0
WH3_k127_8929240_5 PFAM PP-loop domain protein - - - 0.000000000000000000000000000000000001922 148.0
WH3_k127_8929240_6 Protein of unknown function (DUF2281) - - - 0.00000000000000009904 81.0
WH3_k127_8929240_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000007525 76.0
WH3_k127_8929240_8 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.0001746 44.0
WH3_k127_8954986_0 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 304.0
WH3_k127_8954986_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003636 276.0
WH3_k127_8954986_2 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.000000000000000000000000000000000000000000000002075 181.0
WH3_k127_8954986_3 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000000000001028 107.0
WH3_k127_8965980_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 423.0
WH3_k127_8965980_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002043 253.0
WH3_k127_8965980_2 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003352 247.0
WH3_k127_8965980_3 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.00000000000000000001161 96.0
WH3_k127_9065958_0 ATPases associated with a variety of cellular activities K00400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 540.0
WH3_k127_9065958_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 475.0
WH3_k127_9109708_0 Protein of unknown function (DUF655) K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003842 243.0
WH3_k127_9109708_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000003746 182.0
WH3_k127_9109708_2 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000005173 183.0
WH3_k127_9109708_3 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000006477 169.0
WH3_k127_9109708_4 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000000000000000002451 115.0
WH3_k127_9109708_5 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.0000000000000000000000001655 108.0
WH3_k127_9123537_0 TPR Domain containing protein - - - 0.00000000000000000000000000000003444 139.0
WH3_k127_9141878_0 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 3.805e-260 808.0
WH3_k127_9141878_1 PFAM Glutamine amidotransferase, class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 518.0
WH3_k127_9141878_2 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 512.0
WH3_k127_9141878_3 GXGXG motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 299.0
WH3_k127_9141878_4 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000001883 122.0
WH3_k127_9141878_5 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.000000000000000000000000002168 112.0
WH3_k127_9141878_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K12143,K15831 - - 0.0000000003201 68.0
WH3_k127_9151620_0 Proposed homoserine kinase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 453.0
WH3_k127_9151620_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 450.0
WH3_k127_9151620_10 - - - - 0.0000000002147 66.0
WH3_k127_9151620_2 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 304.0
WH3_k127_9151620_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 295.0
WH3_k127_9151620_4 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002559 277.0
WH3_k127_9151620_5 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000009318 268.0
WH3_k127_9151620_6 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000001136 210.0
WH3_k127_9151620_7 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000009602 176.0
WH3_k127_9151620_8 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000001711 115.0
WH3_k127_9151620_9 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000000000000001911 79.0
WH3_k127_9187835_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 453.0
WH3_k127_9187835_1 TIGR00268 family K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006887 252.0
WH3_k127_9187835_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000002816 241.0
WH3_k127_9187835_3 PFAM PP-loop - - - 0.0000000000000000000000000000000000000000001108 163.0
WH3_k127_9187835_4 Transcriptional regulator K07108 - - 0.00000000000000000000000000002471 119.0
WH3_k127_9187835_5 Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000003893 100.0
WH3_k127_9220335_0 - K08963 - 5.3.1.23 3.343e-312 965.0
WH3_k127_9220335_1 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000155 245.0
WH3_k127_9220335_2 PFAM Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000008797 229.0
WH3_k127_9220335_3 DJ-1/PfpI family K03152 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000002269 190.0
WH3_k127_9220335_4 protein N-acetylglucosaminyltransferase activity K12600 - - 0.000000000000000000000000000000000000000004167 161.0
WH3_k127_9220335_5 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000007056 139.0
WH3_k127_9220335_6 TPR repeat-containing protein - - - 0.000000000000000000000000000000003676 138.0
WH3_k127_9224961_0 Tetratricopeptide repeat K12600 - - 0.0000000000000000000000000000000000000000000000000004126 202.0
WH3_k127_9224961_1 COG2897 Rhodanese-related sulfurtransferase - - - 0.00000000000000003368 89.0
WH3_k127_9224961_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000005249 82.0
WH3_k127_9240149_0 Protein of unknown function (DUF1670) - - - 0.00000000000000000000000000000000000000000001482 173.0
WH3_k127_9240149_1 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.00000000000000000000000000000000000000001927 163.0
WH3_k127_9240149_2 Ferrous iron transport K04759 - - 0.00000000000000000000000000000001936 130.0
WH3_k127_9240149_3 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000002074 91.0
WH3_k127_9240149_4 - - - - 0.00000002548 62.0
WH3_k127_9268083_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 551.0
WH3_k127_9268083_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000002747 177.0
WH3_k127_9268083_2 PFAM PUA domain containing protein K07398 - - 0.000000000000000000000000000000000000000009273 158.0
WH3_k127_9304784_0 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 320.0
WH3_k127_9304784_1 cell volume homeostasis K03316,K11105 - - 0.000000000000000000000000000000000000000003997 162.0
WH3_k127_9304784_2 Probable transposase K07496 - - 0.0000000000000000000000000002039 115.0
WH3_k127_9350067_0 TIGRFAM cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 386.0
WH3_k127_9350067_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 368.0
WH3_k127_9350067_10 Uncharacterized protein domain (DUF2202) - - - 0.00000000000000000000000000000000000000000000000002304 188.0
WH3_k127_9350067_11 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.000000000000000000000000000000000000000000001571 179.0
WH3_k127_9350067_12 PFAM Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000000000008243 139.0
WH3_k127_9350067_13 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.00000000000000000000000000006045 121.0
WH3_k127_9350067_14 protein domain (DUF2202) - - - 0.0000000000000000000000001539 119.0
WH3_k127_9350067_15 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000003981 65.0
WH3_k127_9350067_2 Cobyrinic acid ac-diamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 306.0
WH3_k127_9350067_3 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 301.0
WH3_k127_9350067_4 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001666 271.0
WH3_k127_9350067_5 Mediates zinc uptake. May also transport other divalent cations K07238 - - 0.00000000000000000000000000000000000000000000000000000000000193 220.0
WH3_k127_9350067_6 domain protein K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000003818 218.0
WH3_k127_9350067_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000343 212.0
WH3_k127_9350067_8 CGGC - - - 0.000000000000000000000000000000000000000000000000000001519 193.0
WH3_k127_9350067_9 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000006534 197.0
WH3_k127_9392102_0 Carbon-nitrogen hydrolase - - - 2.397e-204 651.0
WH3_k127_9392102_1 Adenosylcobinamide amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 384.0
WH3_k127_9392102_2 CobN/Magnesium Chelatase K02230 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001354 289.0
WH3_k127_9418924_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 480.0
WH3_k127_9418924_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 444.0
WH3_k127_9418924_2 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000006516 188.0
WH3_k127_9418924_3 Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000001793 167.0
WH3_k127_9418924_4 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000002247 127.0
WH3_k127_9418924_5 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000001426 121.0
WH3_k127_9418924_6 Belongs to the acylphosphatase family - - - 0.000000000000000003482 93.0
WH3_k127_9419527_0 PFAM NADH Ubiquinone plastoquinone (complex I) K05568,K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 599.0
WH3_k127_9419527_1 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 513.0
WH3_k127_9419527_2 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 460.0
WH3_k127_9419527_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 356.0
WH3_k127_9419527_4 Domain of unknown function (DUF4040) K05566 - - 0.00000000000000000000000000000000000000000000001116 179.0
WH3_k127_9419527_5 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000000000000000004279 158.0
WH3_k127_9419527_6 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.00000000000000000000000000000000000001778 150.0
WH3_k127_9419527_7 Domain of unknown function (DUF4040) K05566 - - 0.00000000000000000008195 91.0
WH3_k127_9419527_8 Protein of unknown function (DUF1646) - - - 0.00000001468 60.0
WH3_k127_9419527_9 - - - - 0.00008087 49.0
WH3_k127_9440020_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002322 252.0
WH3_k127_9440020_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001629 244.0
WH3_k127_9440020_2 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000002047 229.0
WH3_k127_9440020_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000001226 181.0
WH3_k127_9440020_4 - - - - 0.0000000000000000000000000000000000001738 148.0
WH3_k127_9440020_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.000000000000000001767 86.0
WH3_k127_9446943_0 acid binding OB-fold tRNA helicase-type K07463 - - 2.171e-271 854.0
WH3_k127_9446943_1 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000000000000000000000000000004506 237.0
WH3_k127_9493466_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 398.0
WH3_k127_9493466_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17870 - 1.6.3.3 0.0000000000000000000000000000000000000000000000000000000000000000001283 248.0
WH3_k127_9493466_2 Transposase, Mutator family - - - 0.00000000000000000000000000000194 121.0
WH3_k127_9527488_0 TIGRFAM TraB family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 388.0
WH3_k127_9527488_1 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 325.0
WH3_k127_9527488_2 Serine protease with a broad substrate specificity K17734 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000001243 244.0
WH3_k127_9527488_3 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000001278 184.0
WH3_k127_9527488_4 PFAM Class II Aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000002676 174.0
WH3_k127_9527488_5 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000003243 164.0
WH3_k127_9527488_6 COG2897 Rhodanese-related sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000001631 123.0
WH3_k127_9527488_7 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000008944 123.0
WH3_k127_9527488_8 TIGRFAM transposase, IS605 OrfB family K07496 - - 0.0000000000000000000000001621 109.0
WH3_k127_9563195_0 Serine protease with a broad substrate specificity K17734 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000001088 236.0
WH3_k127_9563195_1 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000001221 183.0
WH3_k127_9569760_0 KH, type 1, domain K07041 - - 2.634e-312 967.0
WH3_k127_9569760_1 SMART regulatory protein, Crp K07730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002775 242.0
WH3_k127_9569760_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000001972 194.0
WH3_k127_9569760_3 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000002511 184.0
WH3_k127_9589925_0 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 297.0
WH3_k127_9589925_1 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000005251 203.0
WH3_k127_9589925_2 TIGRFAM transposase, IS605 OrfB family, central region K07496 - - 0.00001756 47.0
WH3_k127_9643360_0 Isocitrate/isopropylmalate dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 577.0
WH3_k127_9643360_1 Rio2, N-terminal K07179 - 2.7.11.1 0.0000000000000000000000000000000006199 135.0
WH3_k127_9683962_0 Aminotransferase class-III K00836 GO:0003674,GO:0003824,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 579.0
WH3_k127_9683962_1 LOR SDH bifunctional enzyme conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 497.0
WH3_k127_9683962_10 - - - - 0.00000005855 57.0
WH3_k127_9683962_11 Domain of unknown function (DUF4139) - - - 0.0000002661 63.0
WH3_k127_9683962_12 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000005872 55.0
WH3_k127_9683962_13 Domain of unknown function (DUF4139) - - - 0.00006562 55.0
WH3_k127_9683962_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 381.0
WH3_k127_9683962_3 PFAM Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000001782 218.0
WH3_k127_9683962_4 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.000000000000000000000000000000000000000000000000000001148 195.0
WH3_k127_9683962_5 L-2,4-diaminobutyric acid acetyltransferase K06718 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019491,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0042399,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.178 0.000000000000000000000000000000000000000000004552 169.0
WH3_k127_9683962_6 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000007177 161.0
WH3_k127_9683962_7 Bacterial toxin of type II toxin-antitoxin system, YafQ - - - 0.000000000000000000000000000003225 122.0
WH3_k127_9683962_8 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000001836 79.0
WH3_k127_9683962_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000435 66.0
WH3_k127_9725703_0 SWIM zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 289.0
WH3_k127_9725703_1 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002795 268.0
WH3_k127_9725703_2 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.0000001104 57.0
WH3_k127_973274_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 368.0
WH3_k127_973274_1 Cytochrome c biogenesis protein K06196 - - 0.00000009424 62.0
WH3_k127_9759231_0 serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002815 273.0
WH3_k127_9759231_1 KH domain protein K06961 - - 0.0000000000000000000000000000000000000000000000000000000000001972 218.0
WH3_k127_9759231_2 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000000000000000006535 158.0
WH3_k127_9759231_3 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000002093 86.0
WH3_k127_9774185_0 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 527.0
WH3_k127_9774185_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 429.0
WH3_k127_9774185_2 Has ATPase and non-specific DNA-binding activities K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 424.0
WH3_k127_9774185_3 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000005379 212.0
WH3_k127_9774185_4 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000007101 201.0
WH3_k127_9774185_5 - - - - 0.000000000000000000000000000000000000000000004098 175.0
WH3_k127_9792909_0 RNA binding S1 domain protein K06959 - - 1.355e-228 728.0
WH3_k127_9792909_1 VWA domain containing CoxE-like protein K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 595.0
WH3_k127_9792909_10 Cold shock protein K03704 - - 0.000000000000004975 76.0
WH3_k127_9792909_11 - - - - 0.0000001656 58.0
WH3_k127_9792909_12 - - - - 0.0000006007 57.0
WH3_k127_9792909_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 509.0
WH3_k127_9792909_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 320.0
WH3_k127_9792909_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000533 246.0
WH3_k127_9792909_5 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000001501 192.0
WH3_k127_9792909_6 Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000007967 162.0
WH3_k127_9792909_7 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000003296 166.0
WH3_k127_9792909_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000008899 142.0
WH3_k127_9792909_9 phosphorelay signal transduction system - - - 0.0000000000000001156 85.0
WH3_k127_9800647_0 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 588.0
WH3_k127_9800647_1 Metallo-beta-lactamase domain protein K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 424.0
WH3_k127_9800647_2 PFAM Conserved TM helix repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 421.0
WH3_k127_9800647_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 341.0
WH3_k127_9800647_4 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000002098 242.0
WH3_k127_9800647_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000001336 226.0
WH3_k127_9800647_6 PFAM Cupin - - - 0.00000000000000000000000000000000000000003909 155.0
WH3_k127_9800647_7 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000002235 135.0
WH3_k127_9800647_8 PFAM RDD domain containing protein - - - 0.0000000000000000000000000000005715 126.0
WH3_k127_9825713_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.859e-303 943.0
WH3_k127_9825713_1 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 297.0
WH3_k127_9825713_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000005687 174.0
WH3_k127_9825713_3 ester cyclase - - - 0.000000000000000000000000000077 120.0
WH3_k127_9927996_0 Belongs to the catalase family K03781 - 1.11.1.6 4.467e-287 886.0
WH3_k127_9927996_1 Probable transposase K07496 - - 0.0000000000000000000001092 98.0
WH3_k127_9927996_2 PFAM Rubrerythrin - GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000003474 92.0
WH3_k127_9940103_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 577.0
WH3_k127_9940103_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000363 278.0
WH3_k127_9940103_2 TIGRFAM transposase, IS605 OrfB family, central region - - - 0.00000000000000000000000000000000000000000000000000000000005064 220.0
WH3_k127_9940103_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000009133 208.0
WH3_k127_9994301_0 Glycogen synthase - - - 1.021e-198 636.0
WH3_k127_9994301_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 502.0
WH3_k127_9994301_10 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002083 284.0
WH3_k127_9994301_11 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002547 252.0
WH3_k127_9994301_12 Circadian clock protein KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000003013 237.0
WH3_k127_9994301_13 Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP K11176 - 3.5.4.10 0.0000000000000000000000000000000000000000000000000000001943 200.0
WH3_k127_9994301_14 Tetratricopeptide repeat K12600 - - 0.0000000000000000000000000000000000000001648 160.0
WH3_k127_9994301_15 Uncharacterized conserved protein (DUF2299) - - - 0.00000000000000000000000000000000316 134.0
WH3_k127_9994301_16 Membrane K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000009716 121.0
WH3_k127_9994301_17 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.00000000000000000000000006344 109.0
WH3_k127_9994301_18 membrane protein domain - - - 0.000000000000000000000001125 108.0
WH3_k127_9994301_19 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000001634 104.0
WH3_k127_9994301_2 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 462.0
WH3_k127_9994301_20 competence protein COMEC K02238 - - 0.000000000000000000000002993 107.0
WH3_k127_9994301_21 Ion channel - - - 0.0000000000000000226 95.0
WH3_k127_9994301_22 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000005818 56.0
WH3_k127_9994301_3 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 434.0
WH3_k127_9994301_4 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 445.0
WH3_k127_9994301_5 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 365.0
WH3_k127_9994301_6 ABC transporter K01990,K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 362.0
WH3_k127_9994301_7 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 352.0
WH3_k127_9994301_8 PFAM ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 333.0
WH3_k127_9994301_9 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 324.0