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Overview

ID MAG04147
Name WH3_bin.31
Sample SMP0108
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Coriobacteriia
Order Anaerosomatales
Family Anaerosomataceae
Genus UBA6100
Species
Assembly information
Completeness (%) 61.62
Contamination (%) 2.09
GC content (%) 67.0
N50 (bp) 6,403
Genome size (bp) 1,447,767

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1443

Gene name Description KEGG GOs EC E-value Score Sequence
WH3_k127_10030649_0 Belongs to the SEDS family - - - 3.503e-266 847.0
WH3_k127_10030649_1 Kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 477.0
WH3_k127_10030649_10 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000005159 96.0
WH3_k127_10030649_11 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000002531 72.0
WH3_k127_10030649_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 383.0
WH3_k127_10030649_3 Reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 319.0
WH3_k127_10030649_4 4Fe-4S binding domain K02572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002148 286.0
WH3_k127_10030649_5 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004137 265.0
WH3_k127_10030649_6 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000001362 183.0
WH3_k127_10030649_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000005111 142.0
WH3_k127_10030649_8 phosphatase 2C K20074 - 3.1.3.16 0.00000000000000000000000000001395 124.0
WH3_k127_10030649_9 response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000001007 106.0
WH3_k127_1009778_0 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000001073 225.0
WH3_k127_1009778_1 PFAM ATP-binding region, ATPase domain protein K07651 - 2.7.13.3 0.000000000000000000000000000000000000000000000000003636 201.0
WH3_k127_1009778_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000004572 102.0
WH3_k127_1009778_3 DnaJ molecular chaperone homology domain - - - 0.0000000000004942 73.0
WH3_k127_10179199_0 PFAM Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 529.0
WH3_k127_10179199_1 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 395.0
WH3_k127_10179199_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000003161 241.0
WH3_k127_10179199_3 Sporulation and spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000001189 230.0
WH3_k127_10179199_4 Protein of unknown function (DUF554) K07150 - - 0.000000000000000000000000000000000000000000000000002639 193.0
WH3_k127_10179199_5 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000002171 148.0
WH3_k127_10179199_6 Redoxin K03564 - 1.11.1.15 0.000000000000000000002104 96.0
WH3_k127_10179199_7 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.000001036 51.0
WH3_k127_10179199_9 YacP-like NYN domain - - - 0.0002915 49.0
WH3_k127_10233745_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.394e-245 782.0
WH3_k127_10233745_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000004425 193.0
WH3_k127_10233745_2 Protein of unknown function (DUF448) K07742 - - 0.0000000001461 66.0
WH3_k127_10275425_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 448.0
WH3_k127_10275425_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.0000000000000000000000001384 108.0
WH3_k127_10275425_2 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339,K05578 - 1.6.5.3 0.000000000000000000000000493 111.0
WH3_k127_10275425_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000001671 92.0
WH3_k127_10275425_4 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000007308 68.0
WH3_k127_10275425_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000002158 58.0
WH3_k127_10300258_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 484.0
WH3_k127_10300258_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000003121 236.0
WH3_k127_10300258_2 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000000000000000000000000000001314 225.0
WH3_k127_10300258_3 PadR family transcriptional regulator K10947 - - 0.000000000000000000000000000000000000004457 149.0
WH3_k127_10300258_4 Putative sensor - - - 0.00000000000000000002389 92.0
WH3_k127_10395027_0 elongation factor G K02355 - - 7.923e-268 842.0
WH3_k127_10395027_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 416.0
WH3_k127_10395027_10 OsmC-like protein K07397 - - 0.0000000000000000000000000000002377 127.0
WH3_k127_10395027_11 Transcriptional regulator, Crp Fnr family K10914 - - 0.0000000000000000000000000006379 122.0
WH3_k127_10395027_12 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000000108 91.0
WH3_k127_10395027_13 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000246 97.0
WH3_k127_10395027_14 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000002955 85.0
WH3_k127_10395027_15 GDSL-like Lipase/Acylhydrolase family - - - 0.0004605 44.0
WH3_k127_10395027_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 401.0
WH3_k127_10395027_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 371.0
WH3_k127_10395027_4 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000002763 263.0
WH3_k127_10395027_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000008903 234.0
WH3_k127_10395027_6 lipid kinase, YegS Rv2252 BmrU family - - - 0.00000000000000000000000000000000000000000000000000000007804 208.0
WH3_k127_10395027_7 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000003393 200.0
WH3_k127_10395027_8 - - - - 0.000000000000000000000000000000000000000000000000003002 201.0
WH3_k127_10395027_9 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000001861 181.0
WH3_k127_10459456_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 502.0
WH3_k127_10459456_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000003841 221.0
WH3_k127_10459456_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000001053 166.0
WH3_k127_10511785_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 425.0
WH3_k127_10511785_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 388.0
WH3_k127_10511785_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 333.0
WH3_k127_10511785_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000001383 200.0
WH3_k127_10511785_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.00000000000000000000000000000000000000000000001843 177.0
WH3_k127_10511785_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000008066 128.0
WH3_k127_10511785_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000004164 121.0
WH3_k127_10511785_7 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000001027 126.0
WH3_k127_10511785_8 Preprotein translocase subunit K03210 - - 0.00000000000000033 82.0
WH3_k127_10511785_9 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000004158 80.0
WH3_k127_10525162_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.076e-315 984.0
WH3_k127_10525162_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 498.0
WH3_k127_10525162_2 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000002007 263.0
WH3_k127_10525162_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000006974 96.0
WH3_k127_10558515_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 439.0
WH3_k127_10558515_1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001482 261.0
WH3_k127_10558515_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000001478 69.0
WH3_k127_10599977_0 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 557.0
WH3_k127_10599977_1 COGs COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000001654 248.0
WH3_k127_10599977_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000001085 193.0
WH3_k127_10599977_3 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000003665 184.0
WH3_k127_10623462_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 343.0
WH3_k127_10623462_1 Efflux ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009576 294.0
WH3_k127_10623462_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000004246 191.0
WH3_k127_10647132_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1238.0
WH3_k127_10647132_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000001488 250.0
WH3_k127_10647132_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000003776 198.0
WH3_k127_1073374_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000002052 230.0
WH3_k127_1073374_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000005139 213.0
WH3_k127_1073374_2 HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668 K07015 - - 0.0000000000000000000000000000001365 130.0
WH3_k127_1073374_3 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000664 102.0
WH3_k127_1073374_4 - - - - 0.00000001337 65.0
WH3_k127_10748_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.177e-228 725.0
WH3_k127_10748_1 Type ii secretion system protein e K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 559.0
WH3_k127_10748_10 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000001527 116.0
WH3_k127_10748_11 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.000000000000000000001633 98.0
WH3_k127_10748_12 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000000006452 85.0
WH3_k127_10748_13 Type ii secretion system K12510 - - 0.000000000003401 73.0
WH3_k127_10748_14 PFAM Flp Fap pilin component K02651 - - 0.00000001959 63.0
WH3_k127_10748_15 TadE-like protein - - - 0.00001705 54.0
WH3_k127_10748_16 Putative Flp pilus-assembly TadE/G-like - - - 0.00008913 55.0
WH3_k127_10748_17 Putative Flp pilus-assembly TadE/G-like - - - 0.0002052 54.0
WH3_k127_10748_2 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001568 254.0
WH3_k127_10748_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000007441 238.0
WH3_k127_10748_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000002252 233.0
WH3_k127_10748_5 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000002018 225.0
WH3_k127_10748_6 NUBPL iron-transfer P-loop NTPase K02282 - - 0.0000000000000000000000000000000000000000000000000001935 202.0
WH3_k127_10748_7 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000003049 194.0
WH3_k127_10748_8 Histidine kinase K02480 - 2.7.13.3 0.0000000000000000000000000000000000000001995 165.0
WH3_k127_10748_9 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000003786 156.0
WH3_k127_10752959_0 ABC transporter, ATP-binding protein K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 296.0
WH3_k127_10752959_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005039 295.0
WH3_k127_10752959_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000000000000000000000000000000000000000004883 166.0
WH3_k127_10752959_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000004796 110.0
WH3_k127_10752959_4 response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000008345 105.0
WH3_k127_10752959_5 cheY-homologous receiver domain - - - 0.00000000003577 64.0
WH3_k127_10828304_0 UPF0182 protein K09118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 601.0
WH3_k127_10828304_1 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000007172 208.0
WH3_k127_10828304_2 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000001383 140.0
WH3_k127_10828304_3 Maf-like protein K06287 - - 0.000000000000000000000001627 117.0
WH3_k127_10828304_4 lyase activity - - - 0.0000000000000000001592 104.0
WH3_k127_10936691_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 359.0
WH3_k127_10936691_1 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K07533 - 5.2.1.8 0.000000000000000000000001782 114.0
WH3_k127_10945408_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 347.0
WH3_k127_10945408_1 HEPN domain - - - 0.00000000002303 74.0
WH3_k127_10945408_2 TRANSCRIPTIONal - - - 0.00000000435 64.0
WH3_k127_10977343_0 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003868 269.0
WH3_k127_10977343_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000006045 262.0
WH3_k127_10977343_2 Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000000000000000000000003335 228.0
WH3_k127_10977343_3 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16787 - - 0.000000000000000000000000000000000000000000000002849 184.0
WH3_k127_10977343_4 ribosomal protein l17 K02879 - - 0.000000000000000000000000000000000001179 143.0
WH3_k127_10977343_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000007537 104.0
WH3_k127_10977343_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000005344 57.0
WH3_k127_11063099_0 TIGRFAM phosphonopyruvate decarboxylase-related protein K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000001547 265.0
WH3_k127_11063099_1 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000001702 202.0
WH3_k127_11063099_2 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000005163 181.0
WH3_k127_11063099_3 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000004604 186.0
WH3_k127_11063099_4 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000008706 179.0
WH3_k127_11063099_5 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.0000000000000000000000006928 120.0
WH3_k127_11105215_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.252e-261 834.0
WH3_k127_11105215_1 ABC-type multidrug transport system ATPase component K01990,K19309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 317.0
WH3_k127_11105215_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000001332 228.0
WH3_k127_11105215_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000002405 155.0
WH3_k127_11105215_4 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000895 112.0
WH3_k127_11151340_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 529.0
WH3_k127_11151340_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 524.0
WH3_k127_11151340_2 FeS-containing Cyanobacterial-specific oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 335.0
WH3_k127_11151340_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 325.0
WH3_k127_11151340_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000006784 249.0
WH3_k127_11151340_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K01498,K11752 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000007982 243.0
WH3_k127_11151340_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000238 230.0
WH3_k127_11151340_7 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000007188 203.0
WH3_k127_11151340_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000002447 147.0
WH3_k127_11155140_0 CHASE3 domain - - - 0.00000000000000000000001665 116.0
WH3_k127_11155140_1 domain, Protein - - - 0.000000000000000000002923 109.0
WH3_k127_11155140_2 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.000000000000000000005923 93.0
WH3_k127_11155140_3 TIGRFAM integral membrane protein TIGR01906 - - - 0.00000000000001229 83.0
WH3_k127_11155140_4 Peptidase family M28 - - - 0.0000003222 63.0
WH3_k127_11373552_0 Chemotaxis protein histidine kinase and related K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001595 236.0
WH3_k127_11373552_1 Chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000003291 248.0
WH3_k127_11373552_2 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000333 145.0
WH3_k127_11373552_3 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000004849 135.0
WH3_k127_11473678_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000001043 192.0
WH3_k127_11473678_1 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 0.00000000000000000000000005412 108.0
WH3_k127_11488107_0 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 438.0
WH3_k127_11488107_1 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 453.0
WH3_k127_11488107_2 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000004208 173.0
WH3_k127_11488107_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001647 132.0
WH3_k127_11488107_4 PIN domain - - - 0.00000000000000001523 89.0
WH3_k127_11488107_5 SpoVT / AbrB like domain - - - 0.00000001019 57.0
WH3_k127_11488107_6 Bacterial PH domain - - - 0.000006755 55.0
WH3_k127_11537078_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000008572 270.0
WH3_k127_11537078_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000277 203.0
WH3_k127_11537078_2 PBS lyase - - - 0.000004922 57.0
WH3_k127_11539415_0 Cation transport ATPase (P-type) K01537 - 3.6.3.8 2.204e-299 945.0
WH3_k127_11539415_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 297.0
WH3_k127_11539415_2 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000356 253.0
WH3_k127_11539415_3 Uncharacterized protein conserved in bacteria (DUF2239) K09965 - - 0.0000000000000000000000000000000000000000000000000000000000001517 222.0
WH3_k127_11539415_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000002646 164.0
WH3_k127_11539415_5 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000000000000005807 167.0
WH3_k127_11539415_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000001927 148.0
WH3_k127_11539415_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000004311 151.0
WH3_k127_11539415_8 - - - - 0.000003613 56.0
WH3_k127_11567864_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 545.0
WH3_k127_11567864_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000001058 206.0
WH3_k127_11567864_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 0.000000000000000000000000000000000000000000000000000000001089 209.0
WH3_k127_11567864_3 FR47-like protein - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.00000000000002068 81.0
WH3_k127_11567864_4 Predicted membrane protein (DUF2207) - - - 0.000000009533 64.0
WH3_k127_11567864_5 Belongs to the thioredoxin family K03671 - - 0.000004406 51.0
WH3_k127_1159872_0 PFAM Alcohol dehydrogenase GroES-like K00004,K00008,K00060 - 1.1.1.103,1.1.1.14,1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 361.0
WH3_k127_1159872_1 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 306.0
WH3_k127_1159872_2 Protein of unknown function (DUF2510) - - - 0.00000001341 63.0
WH3_k127_1159872_3 Metal-dependent hydrolase K07043 - - 0.00005842 50.0
WH3_k127_11598995_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000002861 246.0
WH3_k127_11598995_1 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000003525 238.0
WH3_k127_11598995_2 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000002782 232.0
WH3_k127_11598995_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000006154 98.0
WH3_k127_11652536_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 348.0
WH3_k127_11652536_1 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000009343 224.0
WH3_k127_11652536_2 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000001923 169.0
WH3_k127_11652536_3 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000005499 102.0
WH3_k127_11652536_4 PFAM VanZ like family - - - 0.00000000000000006903 85.0
WH3_k127_11652536_5 denitrification pathway K15876 - - 0.000000000001583 77.0
WH3_k127_11652536_6 4Fe-4S binding domain - - - 0.0000002029 61.0
WH3_k127_11661169_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 365.0
WH3_k127_11661169_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008919 313.0
WH3_k127_11661169_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000001414 226.0
WH3_k127_11661169_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000008548 211.0
WH3_k127_11661169_4 Ribosomal protein L36 K02919 - - 0.0000000000000008331 78.0
WH3_k127_11661169_5 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000008746 65.0
WH3_k127_11668547_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 321.0
WH3_k127_11668547_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001077 259.0
WH3_k127_11668547_2 PDZ DHR GLGF domain protein K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000004812 237.0
WH3_k127_11668547_3 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000182 178.0
WH3_k127_11668547_4 signal transduction histidine kinase K07642 - 2.7.13.3 0.000000000000000000000000000000001504 142.0
WH3_k127_1174945_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 338.0
WH3_k127_1174945_1 PFAM HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006009 246.0
WH3_k127_1174945_2 Acyltransferase - - - 0.0009311 51.0
WH3_k127_11763921_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 443.0
WH3_k127_11763921_1 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000002647 207.0
WH3_k127_11763921_2 Heavy-metal-associated domain - - - 0.0000002869 55.0
WH3_k127_11763921_3 PhoQ Sensor - - - 0.000003043 49.0
WH3_k127_11763921_4 zinc-ribbon domain - - - 0.00007258 52.0
WH3_k127_11784942_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 5.839e-226 720.0
WH3_k127_11784942_1 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 367.0
WH3_k127_11784942_2 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001274 260.0
WH3_k127_11784942_3 CYTH - - - 0.000000000000000000000000000000000002472 145.0
WH3_k127_11784942_4 CHAD domain - - - 0.000000000000000000000000009077 122.0
WH3_k127_11986152_0 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 348.0
WH3_k127_11986152_1 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000001202 121.0
WH3_k127_1214904_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004113 245.0
WH3_k127_1214904_1 YqeY-like protein K09117 - - 0.00000000000000000000000009633 109.0
WH3_k127_1214904_2 Glyoxalase-like domain K08234 - - 0.000000000006159 71.0
WH3_k127_12225707_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 537.0
WH3_k127_12225707_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000000000000000000001993 197.0
WH3_k127_12225707_2 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.000000000000000000000000001527 117.0
WH3_k127_12225707_3 DivIVA domain protein K04074 - - 0.00000000000000000000000001548 118.0
WH3_k127_12225707_4 Belongs to the UPF0235 family K09131 - - 0.000000000000000002027 92.0
WH3_k127_12225707_5 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000002056 76.0
WH3_k127_12487872_0 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 433.0
WH3_k127_12487872_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 343.0
WH3_k127_12487872_2 Subtilase family K01342,K13275 - 3.4.21.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 317.0
WH3_k127_12487872_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000461 215.0
WH3_k127_12487872_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000002229 162.0
WH3_k127_12487872_5 PFAM CMP dCMP deaminase zinc-binding K01489 - 3.5.4.5 0.00000000000000000003485 93.0
WH3_k127_12503033_0 ABC transporter, transmembrane region K06147 - - 1.545e-264 832.0
WH3_k127_12503033_1 ABC transporter, transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 599.0
WH3_k127_12570122_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.698e-242 758.0
WH3_k127_12615879_0 FtsK SpoIIIE family K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 590.0
WH3_k127_12615879_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 387.0
WH3_k127_12615879_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001914 281.0
WH3_k127_12615879_3 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000002388 248.0
WH3_k127_12615879_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000002399 206.0
WH3_k127_12615879_5 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000454 213.0
WH3_k127_12615879_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000001553 184.0
WH3_k127_12615879_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000004793 185.0
WH3_k127_12615879_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000216 86.0
WH3_k127_12615879_9 SMART helix-turn-helix domain protein - - - 0.0000000000000003345 88.0
WH3_k127_12634784_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1080.0
WH3_k127_12634784_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 456.0
WH3_k127_12634784_2 Universal stress protein family - - - 0.0000000000000002418 93.0
WH3_k127_12639578_0 penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 481.0
WH3_k127_12639578_1 Peptidase, U32 family K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 426.0
WH3_k127_12669103_0 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003918 270.0
WH3_k127_12669103_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000002972 89.0
WH3_k127_12669103_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000005181 95.0
WH3_k127_12689627_0 biogenesis protein CcmF K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 518.0
WH3_k127_12689627_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 318.0
WH3_k127_12689627_10 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000005016 124.0
WH3_k127_12689627_11 BioY family K03523 - - 0.0000000000000000000000000000759 122.0
WH3_k127_12689627_2 PFAM ABC transporter K01990,K02193,K09697 - 3.6.3.41,3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 312.0
WH3_k127_12689627_3 PFAM Metallophosphoesterase K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001925 286.0
WH3_k127_12689627_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000003136 267.0
WH3_k127_12689627_5 histidine kinase DNA gyrase B - - - 0.000000000000000000000000000000000000000000000000000000000000000008528 243.0
WH3_k127_12689627_6 heme exporter protein CcmB K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000005093 229.0
WH3_k127_12689627_7 serine-type aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000001045 194.0
WH3_k127_12689627_8 Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000000000008684 152.0
WH3_k127_12689627_9 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000009641 137.0
WH3_k127_12752266_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 548.0
WH3_k127_12752266_1 VanW like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002876 271.0
WH3_k127_12752266_2 ACT domain protein - - - 0.000000000000000000000000000000000000003318 151.0
WH3_k127_1280358_0 L-fucose isomerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002175 268.0
WH3_k127_1280358_1 PFAM PEGA domain - - - 0.000000000000000000000000000000000000000000000000000000000000001393 231.0
WH3_k127_1280358_2 - - - - 0.0000000000002009 77.0
WH3_k127_12875605_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 349.0
WH3_k127_12875605_1 Cysteine desulfurase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 296.0
WH3_k127_12875605_2 PFAM MOSC domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000009211 203.0
WH3_k127_12875605_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000004833 193.0
WH3_k127_12875605_4 Molybdenum cofactor synthesis domain protein - - - 0.0000000000000000000000000000000000000000000671 174.0
WH3_k127_12898372_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 8.853e-297 943.0
WH3_k127_12898372_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003544 271.0
WH3_k127_12898372_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000006735 243.0
WH3_k127_12898372_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000001024 117.0
WH3_k127_12908594_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 387.0
WH3_k127_12908594_1 PFAM glutamate synthase alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001728 279.0
WH3_k127_12908594_2 Belongs to the glutamate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001029 226.0
WH3_k127_12908594_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000002835 111.0
WH3_k127_13006832_0 Methyltransferase K00563 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000000000001019 272.0
WH3_k127_13006832_1 CMP dCMP deaminase, zinc-binding K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000001015 224.0
WH3_k127_13006832_2 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000002005 192.0
WH3_k127_13006832_3 Nitroreductase family - - - 0.000000000000000000000000000009084 122.0
WH3_k127_13006832_4 Transcriptional regulator - - - 0.00000000000000001986 83.0
WH3_k127_13006832_5 - - - - 0.000000000000006788 81.0
WH3_k127_13019082_0 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 409.0
WH3_k127_13019082_1 hemolysin III K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000003854 224.0
WH3_k127_13019082_2 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000003847 164.0
WH3_k127_13019082_3 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000042 150.0
WH3_k127_13019082_4 membrane - - - 0.000000000001728 79.0
WH3_k127_13019082_5 PspC domain - - - 0.0000001897 60.0
WH3_k127_13019082_6 Belongs to the universal stress protein A family - - - 0.000452 51.0
WH3_k127_13027182_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 376.0
WH3_k127_13027182_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 322.0
WH3_k127_13027182_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 330.0
WH3_k127_13027182_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000004007 241.0
WH3_k127_13027182_4 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000007467 229.0
WH3_k127_13027182_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000001487 189.0
WH3_k127_13027182_6 PFAM 3D domain - - - 0.0000000000000000000000000000000000000000008766 170.0
WH3_k127_13027182_7 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000009391 124.0
WH3_k127_13027182_8 Biofilm formation stimulator VEG - - - 0.000000000000000000000002166 104.0
WH3_k127_13027182_9 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation K06412 GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - 0.00000000000000000000007801 105.0
WH3_k127_13070586_0 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002641 246.0
WH3_k127_13070586_1 PFAM diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.00000000000000000000000000000000000000000000000000000000000003419 222.0
WH3_k127_13070586_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000001401 128.0
WH3_k127_13070586_3 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000006603 124.0
WH3_k127_13070586_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000003058 106.0
WH3_k127_13092413_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 353.0
WH3_k127_13092413_1 protein transpeptidase domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000005626 272.0
WH3_k127_13113202_0 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 385.0
WH3_k127_13113202_1 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 347.0
WH3_k127_13113202_2 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003355 267.0
WH3_k127_13113202_3 R3H domain K06346 - - 0.00000000000000000000000000000000000000000000000004957 190.0
WH3_k127_13113202_4 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000001723 142.0
WH3_k127_13113202_5 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000001333 141.0
WH3_k127_13113202_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000499 52.0
WH3_k127_13113202_7 Membrane protein insertase, YidC Oxa1 family K03217 - - 0.000002135 52.0
WH3_k127_13187473_0 Belongs to the 5'-nucleotidase family - - - 4.563e-196 630.0
WH3_k127_13187473_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 396.0
WH3_k127_13187473_10 PFAM PEGA domain - - - 0.00000000000001648 81.0
WH3_k127_13187473_11 PFAM NapC NirT cytochrome c family, N-terminal region K02569,K03532,K15876 - - 0.0000000003584 64.0
WH3_k127_13187473_12 membrane - - - 0.000001448 60.0
WH3_k127_13187473_2 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 264.0
WH3_k127_13187473_3 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000001098 251.0
WH3_k127_13187473_4 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007294 249.0
WH3_k127_13187473_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000001554 162.0
WH3_k127_13187473_6 cellulase activity - - - 0.00000000000000000000000567 120.0
WH3_k127_13187473_7 - - - - 0.00000000000000000001348 99.0
WH3_k127_13187473_8 Transcriptional regulator PadR-like family K10947 - - 0.0000000000000000001232 93.0
WH3_k127_13187473_9 amine dehydrogenase activity K20276 - - 0.00000000000000002127 98.0
WH3_k127_13218869_0 amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 366.0
WH3_k127_13218869_1 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.000000000000000000000000000000000000000000000000000001131 198.0
WH3_k127_13218869_2 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000027 129.0
WH3_k127_13218869_3 Condensation domain - - - 0.00000000000000000000000000000002976 141.0
WH3_k127_13218869_4 Protein of unknown function (DUF1294) - - - 0.0000000000000000000000000006112 116.0
WH3_k127_13218869_5 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000003099 102.0
WH3_k127_13218869_6 - - - - 0.00000005098 60.0
WH3_k127_1322281_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 602.0
WH3_k127_1322281_1 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000002064 166.0
WH3_k127_1322281_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0000000000000000000000006021 118.0
WH3_k127_13298048_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 550.0
WH3_k127_13298048_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 493.0
WH3_k127_13298048_2 PFAM 2-nitropropane dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 353.0
WH3_k127_13298048_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000004219 178.0
WH3_k127_13298048_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000006835 83.0
WH3_k127_13363827_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1133.0
WH3_k127_13363827_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.000000000000000000000000000000000000000692 152.0
WH3_k127_13363827_2 protein, YerC YecD - - - 0.000000008282 57.0
WH3_k127_13474687_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 508.0
WH3_k127_13474687_1 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009572 238.0
WH3_k127_13474687_2 Serine hydrolase (FSH1) - - - 0.000000000000000000000000008218 117.0
WH3_k127_13474687_3 - - - - 0.00000000000002118 80.0
WH3_k127_13519510_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 475.0
WH3_k127_13519510_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 320.0
WH3_k127_13519510_2 TIGRFAM uroporphyrin-III C-methyltransferase K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000009934 193.0
WH3_k127_13519510_3 Putative heavy-metal-binding - - - 0.000000000000000000000006865 105.0
WH3_k127_1354790_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 591.0
WH3_k127_1354790_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 580.0
WH3_k127_1354790_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046872,GO:0071704,GO:1901576 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 391.0
WH3_k127_1354790_3 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 376.0
WH3_k127_1354790_4 MobA-like NTP transferase domain K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 289.0
WH3_k127_1354790_5 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000287 221.0
WH3_k127_1354790_6 sequence-specific DNA binding - - - 0.0000000000000000000000000000000003079 145.0
WH3_k127_1354790_7 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000006276 134.0
WH3_k127_1354790_8 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000006754 104.0
WH3_k127_1354790_9 glycosyl transferase group 1 - - - 0.000000000004209 78.0
WH3_k127_13602320_0 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 8.625e-223 704.0
WH3_k127_136132_0 PFAM Pyruvate carboxyltransferase K02594 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 522.0
WH3_k127_136132_1 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001642 280.0
WH3_k127_136132_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003528 278.0
WH3_k127_136132_3 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000007338 216.0
WH3_k127_136132_4 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000006258 167.0
WH3_k127_136132_5 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000002391 71.0
WH3_k127_13726056_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000001629 122.0
WH3_k127_13726056_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000002599 101.0
WH3_k127_13728199_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 480.0
WH3_k127_13728199_1 Belongs to the MurCDEF family. MurE subfamily K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 441.0
WH3_k127_13728199_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 362.0
WH3_k127_13728199_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 366.0
WH3_k127_13728199_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 348.0
WH3_k127_13728199_5 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 314.0
WH3_k127_13728199_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 313.0
WH3_k127_13728199_7 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003155 270.0
WH3_k127_13728199_8 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003042 261.0
WH3_k127_13728199_9 Cell division protein FtsQ K03589 - - 0.0000000000159 75.0
WH3_k127_13815087_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 443.0
WH3_k127_13815087_1 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 364.0
WH3_k127_13815087_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 316.0
WH3_k127_13815087_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 293.0
WH3_k127_13815087_4 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000004305 138.0
WH3_k127_13815087_5 Sua5 YciO YrdC YwlC family K07566 - 2.7.7.87 0.00000000000000000000000000000000008873 139.0
WH3_k127_13815087_6 Domain of unknown function DUF302 - - - 0.000000000000000000000000004089 119.0
WH3_k127_13837191_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 340.0
WH3_k127_13837191_1 - - - - 0.0000000000000000000000000000000000000000000000000388 206.0
WH3_k127_13837191_2 PIN domain - - - 0.0000000000000000000000000000000002999 137.0
WH3_k127_13837191_3 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000001866 108.0
WH3_k127_13837191_4 PFAM EAL domain protein - - - 0.000000001938 59.0
WH3_k127_13837191_5 - - - - 0.00009998 48.0
WH3_k127_13839853_0 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 518.0
WH3_k127_13839853_1 Conserved hypothetical ATP binding protein K06945 - - 0.000000000000000000000000000000000000000000001458 168.0
WH3_k127_13839853_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000002047 171.0
WH3_k127_13839853_3 Roadblock/LC7 domain K07131 - - 0.0000000000000000000000000003031 122.0
WH3_k127_1461182_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 520.0
WH3_k127_1461182_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000024 192.0
WH3_k127_1461182_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000147 169.0
WH3_k127_1689425_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 445.0
WH3_k127_1689425_1 - K07341 - - 0.000000000000000000000004276 104.0
WH3_k127_1689425_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000001873 66.0
WH3_k127_1694455_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 452.0
WH3_k127_1694455_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000573 134.0
WH3_k127_1743941_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 353.0
WH3_k127_1743941_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 317.0
WH3_k127_1743941_10 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000002067 110.0
WH3_k127_1743941_11 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000002678 113.0
WH3_k127_1743941_12 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000004183 106.0
WH3_k127_1743941_2 prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 309.0
WH3_k127_1743941_3 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 301.0
WH3_k127_1743941_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001748 273.0
WH3_k127_1743941_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001562 252.0
WH3_k127_1743941_6 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000361 246.0
WH3_k127_1743941_7 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000001272 221.0
WH3_k127_1743941_8 PFAM Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000001208 204.0
WH3_k127_1743941_9 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000009226 163.0
WH3_k127_1830844_0 Family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 362.0
WH3_k127_1830844_1 Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 342.0
WH3_k127_1888067_0 metal-dependent phosphohydrolase 7TM intracellular region K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 359.0
WH3_k127_1896742_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 5.218e-243 764.0
WH3_k127_1896742_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000002876 167.0
WH3_k127_1979485_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 580.0
WH3_k127_1979485_1 40-residue YVTN family beta-propeller - - - 0.0000000000000000000000000000000000000000000000000008264 204.0
WH3_k127_1979485_2 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000005117 184.0
WH3_k127_1979485_3 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000007635 153.0
WH3_k127_1979485_4 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000001506 105.0
WH3_k127_1979485_5 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000001576 113.0
WH3_k127_1979485_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000002858 106.0
WH3_k127_1979485_7 Transcriptional regulator, BadM Rrf2 family - - - 0.0000000000001741 78.0
WH3_k127_1979485_8 - - - - 0.00004116 48.0
WH3_k127_1988947_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 417.0
WH3_k127_1988947_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 389.0
WH3_k127_1988947_10 Putative restriction endonuclease - - - 0.0000000000003138 77.0
WH3_k127_1988947_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 378.0
WH3_k127_1988947_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 349.0
WH3_k127_1988947_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 287.0
WH3_k127_1988947_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001791 284.0
WH3_k127_1988947_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000009443 215.0
WH3_k127_1988947_7 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000002811 210.0
WH3_k127_1988947_8 RIP metalloprotease RseP K11749 - - 0.0000000000000000000000000000000000000000000000000000004127 209.0
WH3_k127_1988947_9 - - - - 0.0000000000000000000000000000000002684 136.0
WH3_k127_2017384_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 415.0
WH3_k127_2017384_1 Methyltransferase K00563 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001205 277.0
WH3_k127_2017384_2 aminopeptidase activity K19701,K19702 - 3.4.11.10,3.4.11.24,3.4.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009134 280.0
WH3_k127_2017384_3 CMP dCMP deaminase, zinc-binding K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000009583 173.0
WH3_k127_2017384_4 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000264 141.0
WH3_k127_2017384_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000003617 116.0
WH3_k127_2035697_0 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 418.0
WH3_k127_2035697_1 Radical SAM - - - 0.000000000000000000000000000000000000000008363 163.0
WH3_k127_2035697_2 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000001214 156.0
WH3_k127_2080878_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 341.0
WH3_k127_2080878_1 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000001334 154.0
WH3_k127_2080878_2 - - - - 0.00000000000000000000005422 108.0
WH3_k127_2080878_3 DNA binding domain, excisionase family - - - 0.00000277 58.0
WH3_k127_2130466_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 383.0
WH3_k127_2130466_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 307.0
WH3_k127_2130466_2 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001957 275.0
WH3_k127_2130466_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000009558 195.0
WH3_k127_2130466_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000003204 60.0
WH3_k127_2130466_5 carbon utilization K02664,K02665,K12280 - - 0.00000006303 63.0
WH3_k127_2176916_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.011e-194 614.0
WH3_k127_2176916_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 550.0
WH3_k127_2176916_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006021 260.0
WH3_k127_2176916_3 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000001014 254.0
WH3_k127_2176916_4 ABC-2 family transporter protein K01992 - - 0.00000003808 64.0
WH3_k127_2184290_0 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000007136 256.0
WH3_k127_2184290_1 Histidine kinase - - - 0.000000000003525 79.0
WH3_k127_2185365_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.182e-275 859.0
WH3_k127_2185365_1 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001329 266.0
WH3_k127_2227564_0 Heat shock 70 kDa protein K04043 - - 1.176e-298 928.0
WH3_k127_2227564_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 403.0
WH3_k127_2227564_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 330.0
WH3_k127_2227564_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000003324 142.0
WH3_k127_2227564_4 MerR HTH family regulatory protein K13640 - - 0.0000000000000000000000000002157 119.0
WH3_k127_226741_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 505.0
WH3_k127_226741_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000004285 242.0
WH3_k127_226741_2 alginic acid biosynthetic process K20276 - - 0.0000000000000000000000000000000000000000000001848 179.0
WH3_k127_226741_3 sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000002028 132.0
WH3_k127_226741_4 4Fe-4S binding domain - - - 0.0000000000000000000175 94.0
WH3_k127_226741_5 - - - - 0.00000000000243 78.0
WH3_k127_2299499_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 394.0
WH3_k127_2299499_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 303.0
WH3_k127_2299499_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000002138 198.0
WH3_k127_2299499_3 4Fe-4S single cluster domain K22226 - - 0.00000000000000000000000000000000000000000004814 175.0
WH3_k127_2299499_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000003008 147.0
WH3_k127_2299499_5 - - - - 0.00000000005574 72.0
WH3_k127_2299499_6 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000002546 58.0
WH3_k127_2299499_7 Tfp pilus assembly protein FimV - - - 0.0009954 50.0
WH3_k127_2581396_0 TIGRFAM DNA polymerase III, alpha subunit K02337,K14162 - 2.7.7.7 1.757e-215 706.0
WH3_k127_2581396_1 ribonuclease BN K07058 - - 0.000000000000000003109 93.0
WH3_k127_2601669_0 helicase superfamily c-terminal domain K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 581.0
WH3_k127_2601669_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 560.0
WH3_k127_2601669_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000006548 147.0
WH3_k127_2612103_0 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 458.0
WH3_k127_2612103_1 coenzyme F420 hydrogenase activity K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000973 223.0
WH3_k127_27692_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 517.0
WH3_k127_27692_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 466.0
WH3_k127_27692_10 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.00000000000000000000000000000001618 134.0
WH3_k127_27692_11 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000008859 99.0
WH3_k127_27692_2 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 446.0
WH3_k127_27692_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 414.0
WH3_k127_27692_4 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 417.0
WH3_k127_27692_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002744 274.0
WH3_k127_27692_6 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001577 250.0
WH3_k127_27692_7 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000002229 208.0
WH3_k127_27692_8 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000007088 196.0
WH3_k127_27692_9 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000001152 196.0
WH3_k127_2842338_0 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 351.0
WH3_k127_2842338_1 COG1321 Mn-dependent transcriptional regulator K03709 - - 0.0000000000000000000000000000000000000000008544 167.0
WH3_k127_2842338_2 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000004171 115.0
WH3_k127_2984425_0 Belongs to the arginase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 318.0
WH3_k127_3023649_0 histidine kinase DNA gyrase B K07704 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 348.0
WH3_k127_3023649_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 338.0
WH3_k127_3023649_2 response regulator receiver K07705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
WH3_k127_3023649_3 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.00000000000000000000000000006326 122.0
WH3_k127_3023649_4 response to heat K07090 - - 0.0000000000000000000000001033 116.0
WH3_k127_3023649_5 AMP binding - - - 0.0000000000000000000000009884 112.0
WH3_k127_3023649_6 Protein of unknown function, DUF485 - - - 0.00000000000000000005956 97.0
WH3_k127_3023649_7 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000003211 82.0
WH3_k127_3036737_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 598.0
WH3_k127_3036737_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 367.0
WH3_k127_3036737_2 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000001565 154.0
WH3_k127_3099264_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 576.0
WH3_k127_3099264_1 PFAM 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 410.0
WH3_k127_3099264_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 365.0
WH3_k127_3099264_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 338.0
WH3_k127_3099264_4 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 297.0
WH3_k127_3099264_5 DRTGG domain K13788 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000003 270.0
WH3_k127_3099264_6 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000007859 207.0
WH3_k127_3146368_0 Radical SAM domain protein - - - 9.744e-216 686.0
WH3_k127_3146368_1 Cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 479.0
WH3_k127_3146368_10 Part of a membrane complex involved in electron transport K03617 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000001633 184.0
WH3_k127_3146368_11 protein domain associated with - - - 0.00000000000000000000000000000000000000000000001696 184.0
WH3_k127_3146368_12 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000004248 177.0
WH3_k127_3146368_13 ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000001052 141.0
WH3_k127_3146368_14 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.0000000000000000000000000000000002766 142.0
WH3_k127_3146368_15 Tetratricopeptide repeat - - - 0.0000000000000000000001142 108.0
WH3_k127_3146368_16 Part of a membrane complex involved in electron transport K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000002725 87.0
WH3_k127_3146368_17 rod shape-determining protein (MreD) K03571 - - 0.000000000003967 73.0
WH3_k127_3146368_18 NusG domain II - - - 0.00000000005807 70.0
WH3_k127_3146368_19 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000002414 62.0
WH3_k127_3146368_2 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 483.0
WH3_k127_3146368_3 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 402.0
WH3_k127_3146368_4 Belongs to the SEDS family K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 300.0
WH3_k127_3146368_5 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000672 259.0
WH3_k127_3146368_6 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000006725 238.0
WH3_k127_3146368_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000004626 209.0
WH3_k127_3146368_8 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000004074 202.0
WH3_k127_3146368_9 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000008207 188.0
WH3_k127_3149812_0 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000004344 220.0
WH3_k127_3149812_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000002853 142.0
WH3_k127_3149812_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000478 126.0
WH3_k127_3149812_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000004518 121.0
WH3_k127_321190_0 PFAM Bacterial protein of - - - 0.00000000000000000000000000000000000000000000000000000000000003291 232.0
WH3_k127_321190_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000102 91.0
WH3_k127_3229993_0 RF-1 domain - - - 0.000000000000000000000003211 106.0
WH3_k127_3229993_1 small multi-drug export protein - - - 0.0000000000000000000009346 100.0
WH3_k127_3229993_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000004655 68.0
WH3_k127_3329712_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 1.217e-196 632.0
WH3_k127_3329712_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 290.0
WH3_k127_3329712_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000477 95.0
WH3_k127_3364289_0 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001042 274.0
WH3_k127_3364289_1 TIGRFAM phosphodiesterase, MJ0936 - - - 0.00000000000000000000000000000000000004262 160.0
WH3_k127_3364289_2 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000003385 104.0
WH3_k127_3627041_0 fructose-1,6-bisphosphatase K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 365.0
WH3_k127_3627041_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604,K03500 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.1.176,2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001267 261.0
WH3_k127_3627041_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000009945 264.0
WH3_k127_3627041_3 Putative regulatory protein - - - 0.000000000000005081 79.0
WH3_k127_3627041_4 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000002803 58.0
WH3_k127_3633707_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1238.0
WH3_k127_3633707_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 7.104e-217 692.0
WH3_k127_3633707_2 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000005311 162.0
WH3_k127_3633707_3 Domain of unknown function (DUF4440) - - - 0.000000006133 63.0
WH3_k127_3633707_4 PFAM S-layer homology domain - - - 0.000952 47.0
WH3_k127_3634203_0 Phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 409.0
WH3_k127_3634203_1 Radical SAM K18537,K21224 - - 0.00000000000000000000000000001943 126.0
WH3_k127_3634203_2 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000002508 78.0
WH3_k127_3634203_3 4Fe-4S single cluster domain - - - 0.0002558 52.0
WH3_k127_3692403_0 radical SAM domain protein K04034 GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.21.98.3 4.888e-211 669.0
WH3_k127_3692403_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004091 274.0
WH3_k127_3692403_2 PFAM KWG Leptospira - - - 0.000000000000000000000000000000000000000003536 170.0
WH3_k127_3692403_3 Tryptophan-rich sensory protein K05770 - - 0.000000000000000000000000000000000000000007585 158.0
WH3_k127_3692403_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000008591 145.0
WH3_k127_3692403_5 UPF0126 domain - - - 0.000000000000000000000000000000000005765 147.0
WH3_k127_3692403_6 HD domain - - - 0.0000000000000000000000003725 107.0
WH3_k127_3725611_0 L-glutamate biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 458.0
WH3_k127_3725611_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 338.0
WH3_k127_3725611_2 Histidine kinase K00936 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000002765 262.0
WH3_k127_3725611_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001121 251.0
WH3_k127_3725611_4 Response regulator receiver K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000003673 228.0
WH3_k127_3725611_5 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K21053 - 3.5.4.2,3.5.4.4 0.0000000000000000000000000000000002153 135.0
WH3_k127_3726592_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 405.0
WH3_k127_3726592_1 KR domain K04708 - 1.1.1.102 0.000000000000000000000000000000000000000000000000000001632 205.0
WH3_k127_3726592_2 Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000001131 193.0
WH3_k127_3726592_3 PFAM Cytochrome c assembly protein - - - 0.00000000000001726 83.0
WH3_k127_3726592_4 - - - - 0.00005869 48.0
WH3_k127_3826078_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000174 228.0
WH3_k127_3826078_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000002484 149.0
WH3_k127_3826078_2 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000991 116.0
WH3_k127_3826078_3 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000001273 97.0
WH3_k127_3826078_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000001606 50.0
WH3_k127_3826992_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 393.0
WH3_k127_3826992_1 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K18286 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 333.0
WH3_k127_3883806_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.812e-219 685.0
WH3_k127_3883806_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000004165 109.0
WH3_k127_3883806_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0008150,GO:0040007 2.5.1.7 0.000000000000118 73.0
WH3_k127_3885464_0 Integral membrane protein (Pin domain superfamily) - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000004568 249.0
WH3_k127_3885464_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000005361 200.0
WH3_k127_3885464_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000004397 108.0
WH3_k127_3899893_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 531.0
WH3_k127_3899893_1 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 449.0
WH3_k127_3899893_2 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 327.0
WH3_k127_3899893_3 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 294.0
WH3_k127_3899893_4 - - - - 0.000000000000000000000000001323 129.0
WH3_k127_3905528_0 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 294.0
WH3_k127_3905528_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001873 253.0
WH3_k127_3905528_2 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000001638 229.0
WH3_k127_3952321_0 Endoribonuclease that initiates mRNA decay K18682 - - 4.827e-216 681.0
WH3_k127_3952321_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 528.0
WH3_k127_3952321_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 407.0
WH3_k127_3952321_3 histidine kinase DNA gyrase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 366.0
WH3_k127_3952321_4 PFAM PHP domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000003035 233.0
WH3_k127_3952321_5 Stage V sporulation protein S K06416 - - 0.00000000000000000000000000000000006146 139.0
WH3_k127_3952321_6 regulation of DNA repair K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000002051 76.0
WH3_k127_3952321_7 pfam ammecr1 K06990,K09141 - - 0.00000000009088 69.0
WH3_k127_3956665_0 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 395.0
WH3_k127_3956665_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000681 237.0
WH3_k127_3956665_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000003621 96.0
WH3_k127_4001297_0 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 5.496e-275 857.0
WH3_k127_4001297_1 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 584.0
WH3_k127_4001297_2 GIY-YIG type nucleases (URI domain) K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000001899 233.0
WH3_k127_4001297_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000005486 194.0
WH3_k127_4001297_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000001758 161.0
WH3_k127_4001297_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000003466 96.0
WH3_k127_4002348_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000008603 209.0
WH3_k127_4002348_1 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000001117 211.0
WH3_k127_4002348_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000001008 175.0
WH3_k127_4002348_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000005251 147.0
WH3_k127_4002348_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000001635 57.0
WH3_k127_4002348_5 response regulator receiver K03413 - - 0.0002728 52.0
WH3_k127_4052811_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 305.0
WH3_k127_4052811_1 PIN domain K07175 - - 0.00000000000000000003632 103.0
WH3_k127_4052811_2 Tetratricopeptide repeat - - - 0.000000001809 69.0
WH3_k127_407869_0 Bacterial protein of unknown function (DUF853) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 593.0
WH3_k127_407869_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 313.0
WH3_k127_407869_3 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000002341 76.0
WH3_k127_407869_4 PFAM ferredoxin - - - 0.0000005898 53.0
WH3_k127_4129288_0 TIGRFAM histidinol phosphate phosphatase HisJ K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000001585 245.0
WH3_k127_4129288_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000002077 198.0
WH3_k127_4136330_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 7.445e-194 621.0
WH3_k127_4136330_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 377.0
WH3_k127_4136330_2 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 354.0
WH3_k127_4136330_3 PFAM ATP-binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 302.0
WH3_k127_4136330_4 Histidine kinase - - - 0.000000000000000000000000000000000000000001819 165.0
WH3_k127_4136330_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000009454 117.0
WH3_k127_4136330_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000007942 88.0
WH3_k127_4182416_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 287.0
WH3_k127_4182416_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001809 270.0
WH3_k127_4182416_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000001477 237.0
WH3_k127_4182416_3 amino acid K01999 - - 0.000000000000000000000000000000000000000003064 168.0
WH3_k127_4216861_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 499.0
WH3_k127_4216861_1 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000009314 174.0
WH3_k127_4216861_2 Putative cell wall binding repeat 2 - - - 0.00000000001468 75.0
WH3_k127_4216861_3 - - - - 0.0000004409 57.0
WH3_k127_4435_0 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 366.0
WH3_k127_4435_1 4Fe-4S ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000007215 226.0
WH3_k127_4435_2 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000003594 195.0
WH3_k127_4435_3 QueT transporter - - - 0.0000000000000000000000000000000000000000000000007128 185.0
WH3_k127_4435_4 Diguanylate cyclase - - - 0.0000000000000000000000003392 122.0
WH3_k127_4435_5 Transcriptional regulatory protein, C terminal - - - 0.000447 42.0
WH3_k127_4461880_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 378.0
WH3_k127_4472700_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000002794 61.0
WH3_k127_4517625_0 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation K07067 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 360.0
WH3_k127_4517625_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000001876 209.0
WH3_k127_4537233_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.977e-242 762.0
WH3_k127_4537233_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 387.0
WH3_k127_4555770_0 PFAM LOR SDH bifunctional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 397.0
WH3_k127_4555770_1 Putative sensor - - - 0.00000000000000000000000000000000000000000000000000000000001993 214.0
WH3_k127_4555770_2 HAMAP Peptide methionine sulfoxide reductase msrB K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000001475 182.0
WH3_k127_4555770_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000006433 157.0
WH3_k127_4555770_4 N-terminal domain of toast_rack, DUF2154 - - - 0.000000000000000000000000000000000617 141.0
WH3_k127_4555770_5 LOR/SDH bifunctional enzyme conserved region - - - 0.0000001956 59.0
WH3_k127_4584865_0 Magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 532.0
WH3_k127_4584865_1 Metal ion transporter, metal ion (Mn2 Fe2 ) transporter (Nramp) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 449.0
WH3_k127_4584865_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000002134 175.0
WH3_k127_4584865_3 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000002137 139.0
WH3_k127_4584865_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000002568 136.0
WH3_k127_4584865_5 YbaK prolyl-tRNA - - - 0.00000000000000000000000001678 114.0
WH3_k127_4584865_6 PFAM PRC-barrel domain - - - 0.00000000000000000006989 99.0
WH3_k127_465196_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 347.0
WH3_k127_465196_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000003827 184.0
WH3_k127_465196_2 NADH dehydrogenase (Ubiquinone), 30 kDa subunit K00332,K14089 - 1.6.5.3 0.00003759 52.0
WH3_k127_4657043_0 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000004858 189.0
WH3_k127_4657043_1 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000001586 108.0
WH3_k127_4657043_2 Nitroreductase family - - - 0.0000000000000003322 85.0
WH3_k127_4692101_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 459.0
WH3_k127_4692101_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 405.0
WH3_k127_4692101_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 318.0
WH3_k127_4692101_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 318.0
WH3_k127_4692101_4 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005193 286.0
WH3_k127_4692101_5 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004296 254.0
WH3_k127_4692101_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000007243 222.0
WH3_k127_4692101_7 PFAM Class II aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000001681 194.0
WH3_k127_4692101_8 COG NOG29868 non supervised orthologous group - - - 0.00086 51.0
WH3_k127_4726567_0 PFAM ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 334.0
WH3_k127_4726567_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 320.0
WH3_k127_4726567_2 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000004072 192.0
WH3_k127_4726567_3 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000387 119.0
WH3_k127_4726567_4 Sulfurtransferase TusA K04085 - - 0.0000000000512 65.0
WH3_k127_4726567_5 Protein of unknown function (DUF4013) - - - 0.000009176 56.0
WH3_k127_480987_0 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 453.0
WH3_k127_480987_1 Protein of unknown function DUF72 - - - 0.000000000000000000000007467 102.0
WH3_k127_480987_2 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000004206 94.0
WH3_k127_480987_3 TAP-like protein K00627 - 2.3.1.12 0.00000001343 66.0
WH3_k127_480987_5 - - - - 0.0005687 47.0
WH3_k127_4844697_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008633 284.0
WH3_k127_4844697_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004736 262.0
WH3_k127_484691_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 5e-324 1014.0
WH3_k127_484691_1 - - - - 0.00006877 53.0
WH3_k127_4953646_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 291.0
WH3_k127_4953646_1 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000002326 214.0
WH3_k127_4953646_2 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000009513 218.0
WH3_k127_4953646_3 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000002487 162.0
WH3_k127_4953646_4 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000001676 169.0
WH3_k127_4953646_5 PFAM CheW domain protein K03408 - - 0.000000000000000000003802 104.0
WH3_k127_4953646_6 cysteine desulfurase family protein - - - 0.0000000000007957 69.0
WH3_k127_4953646_7 Protein of unknown function (DUF3343) - - - 0.00002014 52.0
WH3_k127_4970400_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 518.0
WH3_k127_4970400_1 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 477.0
WH3_k127_4970400_2 TipAS antibiotic-recognition domain K21744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000173 278.0
WH3_k127_4970400_3 Flavodoxin domain - - - 0.00000000000000000000000000000000000000000000000000000597 201.0
WH3_k127_4970400_4 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000004233 132.0
WH3_k127_4970400_5 COGs COG4087 Soluble P-type ATPase - - - 0.0000000000000000000000000000004281 126.0
WH3_k127_4970400_6 EamA-like transporter family - - - 0.0000000000000000001815 99.0
WH3_k127_5048243_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 9.954e-210 668.0
WH3_k127_5048243_1 DnaQ family exonuclease DinG family helicase K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 373.0
WH3_k127_5048243_2 TIGRFAM L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000001869 222.0
WH3_k127_5048243_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000004511 101.0
WH3_k127_5048243_4 PFAM FeoA family protein K04758 - - 0.00000000000001773 77.0
WH3_k127_5054560_0 unusual protein kinase - - - 2.605e-204 651.0
WH3_k127_5054560_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000001026 178.0
WH3_k127_5054560_2 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000004556 85.0
WH3_k127_506779_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 563.0
WH3_k127_506779_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 521.0
WH3_k127_506779_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000234 109.0
WH3_k127_506779_11 - - - - 0.00000000000000000000002462 111.0
WH3_k127_506779_12 Preprotein translocase SecG subunit K03075 - - 0.00000000000000003176 85.0
WH3_k127_506779_13 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000006549 89.0
WH3_k127_506779_14 - - - - 0.0000001865 59.0
WH3_k127_506779_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 495.0
WH3_k127_506779_3 pathway, signal sequence K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 500.0
WH3_k127_506779_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 353.0
WH3_k127_506779_5 May be required for sporulation K09762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 334.0
WH3_k127_506779_6 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 320.0
WH3_k127_506779_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 285.0
WH3_k127_506779_8 PFAM Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001911 247.0
WH3_k127_506779_9 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000003547 249.0
WH3_k127_5124425_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.005e-237 748.0
WH3_k127_5124425_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 523.0
WH3_k127_5124425_2 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002873 249.0
WH3_k127_5168635_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070,K03789,K14742 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004596,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006464,GO:0006473,GO:0006474,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008999,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0030312,GO:0031365,GO:0032991,GO:0034212,GO:0034470,GO:0034641,GO:0034660,GO:0036211,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051604,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.128,2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 460.0
WH3_k127_5168635_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000001572 227.0
WH3_k127_5168635_2 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000001616 224.0
WH3_k127_5168635_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000001591 192.0
WH3_k127_5168635_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000009215 165.0
WH3_k127_5168635_5 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000003217 158.0
WH3_k127_5168635_6 Hydrolase, P-loop family K06925 - - 0.00000000000000000000000000000000000002414 153.0
WH3_k127_5168635_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000169 152.0
WH3_k127_5168635_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000002201 130.0
WH3_k127_5184395_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 581.0
WH3_k127_5236575_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 462.0
WH3_k127_5236575_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000001086 54.0
WH3_k127_528738_0 UPF0210 protein K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 593.0
WH3_k127_5300960_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 2.264e-223 733.0
WH3_k127_5403097_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 325.0
WH3_k127_5403097_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000009417 139.0
WH3_k127_54090_0 Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 293.0
WH3_k127_54090_1 PFAM Iron-binding zinc finger CDGSH type - - - 0.0000000000000000002914 90.0
WH3_k127_54090_2 Ribosomal protein L6 K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001446 66.0
WH3_k127_54090_3 SpoVT / AbrB like domain - - - 0.00000002654 56.0
WH3_k127_5456293_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 492.0
WH3_k127_5456293_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 449.0
WH3_k127_5456293_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000002041 237.0
WH3_k127_5456293_3 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.0001221 50.0
WH3_k127_5482757_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 418.0
WH3_k127_5482757_1 Thiamine pyrophosphokinase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 404.0
WH3_k127_5482757_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 394.0
WH3_k127_5482757_3 integral membrane protein MviN K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 360.0
WH3_k127_5482757_4 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000001809 271.0
WH3_k127_5482757_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001103 239.0
WH3_k127_5482757_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000003237 168.0
WH3_k127_5482757_7 Copper transport outer membrane protein, MctB - - - 0.00000000001611 74.0
WH3_k127_5541119_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 291.0
WH3_k127_5541119_1 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000004232 252.0
WH3_k127_5541119_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000007387 94.0
WH3_k127_5541119_3 - - - - 0.00005988 53.0
WH3_k127_5562886_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 506.0
WH3_k127_5562886_1 ABC transporter K02028,K09972,K10041 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 381.0
WH3_k127_5562886_2 Tryptophan/tyrosine permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001413 256.0
WH3_k127_5562886_3 - - - - 0.00000000000000000000000000001407 132.0
WH3_k127_5578499_0 Telomere recombination K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000001223 231.0
WH3_k127_5578499_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.000000000000000000000000000000000000000000000000005025 184.0
WH3_k127_5602814_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 484.0
WH3_k127_5602814_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000246 238.0
WH3_k127_5602814_2 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000008117 196.0
WH3_k127_5602814_3 Hydrolase, HD family - - - 0.00000000000000000000000000000000000000000352 164.0
WH3_k127_5602814_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000003082 154.0
WH3_k127_5602814_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000002701 143.0
WH3_k127_5602814_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000005023 132.0
WH3_k127_5602814_7 Chagasin family peptidase inhibitor I42 K14475 - - 0.00000000000000003413 86.0
WH3_k127_5602814_8 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000385 66.0
WH3_k127_5607083_0 citrate synthase K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 579.0
WH3_k127_5607083_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003082 277.0
WH3_k127_5607083_10 - - - - 0.0007066 46.0
WH3_k127_5607083_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002243 264.0
WH3_k127_5607083_3 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000756 251.0
WH3_k127_5607083_4 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000007189 237.0
WH3_k127_5607083_5 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000499 239.0
WH3_k127_5607083_6 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000001231 164.0
WH3_k127_5607083_7 PFAM regulatory protein, MerR - - - 0.0000000000000003017 88.0
WH3_k127_5607083_8 Domain of unknown function (DUF4345) - - - 0.000003217 55.0
WH3_k127_5607083_9 - - - - 0.00007058 50.0
WH3_k127_5662897_0 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 312.0
WH3_k127_5662897_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 294.0
WH3_k127_5662897_2 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008093 241.0
WH3_k127_5662897_3 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000006043 119.0
WH3_k127_5662897_4 EamA-like transporter family - - - 0.000000000000000000000000000242 127.0
WH3_k127_5662897_5 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000001032 83.0
WH3_k127_5662897_6 Domain of unknown function DUF302 - - - 0.0000000325 59.0
WH3_k127_5662897_7 Regulatory protein, FmdB family - - - 0.000003517 51.0
WH3_k127_5830553_0 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 533.0
WH3_k127_5830553_1 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 476.0
WH3_k127_5830553_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000006382 164.0
WH3_k127_5830553_11 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000003352 106.0
WH3_k127_5830553_12 - - - - 0.0000000000000000000002903 104.0
WH3_k127_5830553_13 - - - - 0.00002997 47.0
WH3_k127_5830553_2 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 451.0
WH3_k127_5830553_3 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 366.0
WH3_k127_5830553_4 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05568 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 365.0
WH3_k127_5830553_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 334.0
WH3_k127_5830553_6 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004953 255.0
WH3_k127_5830553_7 PFAM NADH Ubiquinone plastoquinone (complex I) K05568,K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001217 256.0
WH3_k127_5830553_8 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000004585 192.0
WH3_k127_5830553_9 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000008673 169.0
WH3_k127_5841229_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008136 265.0
WH3_k127_5841229_1 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000008558 254.0
WH3_k127_5841229_2 - - - - 0.000000000000000000000002013 107.0
WH3_k127_5856624_0 TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 443.0
WH3_k127_5856624_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 386.0
WH3_k127_5856624_2 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002939 282.0
WH3_k127_5856624_3 - - - - 0.000000000000000000000000000000000000000000000000414 185.0
WH3_k127_5856624_4 heme binding K21472 - - 0.00000000000000000000001082 116.0
WH3_k127_5856624_5 VanZ like family - - - 0.000000000001301 76.0
WH3_k127_5856624_6 hydrolase K01048 - 3.1.1.5 0.00000006877 57.0
WH3_k127_5929923_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 497.0
WH3_k127_5929923_1 small multidrug export protein - - - 0.000000000000000000002399 99.0
WH3_k127_5929923_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000007074 81.0
WH3_k127_5941278_0 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002713 278.0
WH3_k127_5941278_1 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000003538 121.0
WH3_k127_5941278_2 protein, YerC YecD - - - 0.000000000000000000000007394 106.0
WH3_k127_5941278_3 PilT protein domain protein - - - 0.00000001377 61.0
WH3_k127_5979128_0 FAD-dependent K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 527.0
WH3_k127_5979128_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 443.0
WH3_k127_5979128_10 Predicted membrane protein (DUF2232) - - - 0.00002123 56.0
WH3_k127_5979128_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000001868 188.0
WH3_k127_5979128_3 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000008164 184.0
WH3_k127_5979128_4 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000001357 160.0
WH3_k127_5979128_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000002814 137.0
WH3_k127_5979128_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000002844 110.0
WH3_k127_5979128_7 - - - - 0.000000000004231 69.0
WH3_k127_5979128_8 Peptidase family M23 - - - 0.00000000005958 73.0
WH3_k127_6012370_0 Belongs to the peptidase S8 family K01280 - 3.4.14.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 346.0
WH3_k127_6012370_1 ABC-type antimicrobial peptide transport system, permease component K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000003807 94.0
WH3_k127_601252_0 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000002411 147.0
WH3_k127_601252_1 denitrification pathway - - - 0.00000000000000000000000000000485 130.0
WH3_k127_601252_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000009449 130.0
WH3_k127_601252_3 denitrification pathway - - - 0.0000000009796 70.0
WH3_k127_6120651_0 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000007037 174.0
WH3_k127_6120651_1 - - - - 0.000000000000000000000005295 117.0
WH3_k127_6120651_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000008669 83.0
WH3_k127_6120651_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000001554 52.0
WH3_k127_6206064_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 452.0
WH3_k127_6206064_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 349.0
WH3_k127_6206064_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000005588 234.0
WH3_k127_6215590_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 260.0
WH3_k127_6215590_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000132 272.0
WH3_k127_6215590_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000003861 64.0
WH3_k127_6301851_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 377.0
WH3_k127_6301851_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000001842 109.0
WH3_k127_6322177_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 509.0
WH3_k127_6322177_1 Mg chelatase-like protein K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 402.0
WH3_k127_6322177_2 tyrosine recombinase XerC K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001562 257.0
WH3_k127_6322177_3 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000002169 237.0
WH3_k127_6322177_4 Sigma-70, region 4 K02405 - - 0.0000000000000000000000000000000000000000000000000000000006464 205.0
WH3_k127_6357247_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 372.0
WH3_k127_6357247_1 - - - - 0.000000000000000000000000000000000002618 151.0
WH3_k127_6357247_2 Bacterial transcription activator, effector binding domain - - - 0.00000000000000002039 89.0
WH3_k127_6364010_0 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 327.0
WH3_k127_6364010_1 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000002889 177.0
WH3_k127_6364010_2 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.0000000000000000003576 104.0
WH3_k127_6364010_4 DNA polymerase alpha chain like domain - - - 0.0000000000003118 78.0
WH3_k127_6364010_5 PFAM chitin-binding domain 3 protein - - - 0.000000000003214 81.0
WH3_k127_640465_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000468 201.0
WH3_k127_640465_1 Belongs to the UPF0237 family K07166 - - 0.0000000000000000000000001384 108.0
WH3_k127_640465_2 Protein conserved in bacteria - - - 0.000000000000004033 79.0
WH3_k127_640465_4 UPF0210 protein K09157 - - 0.000006361 48.0
WH3_k127_6435595_0 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000414 88.0
WH3_k127_6435595_1 PFAM CHAD domain containing protein - - - 0.00000000003844 70.0
WH3_k127_6466855_0 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 371.0
WH3_k127_6466855_1 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001275 285.0
WH3_k127_6466855_10 Ferric uptake regulator family K03711 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000002643 96.0
WH3_k127_6466855_11 - - - - 0.00001612 55.0
WH3_k127_6466855_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000001709 252.0
WH3_k127_6466855_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000001633 244.0
WH3_k127_6466855_4 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000009861 215.0
WH3_k127_6466855_5 ATPases associated with a variety of cellular activities K02006 - - 0.00000000000000000000000000000000000000000000000000000000007269 216.0
WH3_k127_6466855_6 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000007611 213.0
WH3_k127_6466855_7 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000006222 121.0
WH3_k127_6466855_8 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000003404 121.0
WH3_k127_6466855_9 PFAM Cobalt transport protein K02008 - - 0.00000000000000000000003818 109.0
WH3_k127_6507657_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000002131 242.0
WH3_k127_6507657_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000006287 210.0
WH3_k127_6507657_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000007894 194.0
WH3_k127_6507657_3 abc transporter atp-binding protein K05847 - - 0.0003502 49.0
WH3_k127_6528603_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 372.0
WH3_k127_6528603_1 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000008403 209.0
WH3_k127_6533887_0 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 421.0
WH3_k127_6533887_1 heat shock protein binding - - - 0.0000000000000000000000000000000000007378 154.0
WH3_k127_6533887_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000001521 123.0
WH3_k127_6533887_3 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000001119 118.0
WH3_k127_6547616_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 4.347e-290 900.0
WH3_k127_6547616_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 299.0
WH3_k127_6547616_2 COG0455 ATPases involved in chromosome partitioning K03496,K03609 - - 0.000000000000000000000000000000000000000000000000000000004804 216.0
WH3_k127_6595887_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 494.0
WH3_k127_6595887_1 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000062 176.0
WH3_k127_6595887_2 Sua5 YciO YrdC YwlC family K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000928 168.0
WH3_k127_6661359_0 Chemotaxis protein CheA K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 481.0
WH3_k127_6661359_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 411.0
WH3_k127_6661359_2 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000003437 194.0
WH3_k127_6661359_3 Peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000001824 185.0
WH3_k127_6661359_4 CheC-like family K03410 - - 0.000000000000000000000000000000000000001616 154.0
WH3_k127_6661359_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000003498 150.0
WH3_k127_6661359_6 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000008586 160.0
WH3_k127_6661359_7 NLP P60 protein K21471 - - 0.0000000000000000000000000000000000001321 155.0
WH3_k127_6661359_8 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000228 123.0
WH3_k127_6661359_9 VanZ like family - - - 0.000000000007473 67.0
WH3_k127_6664213_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1127.0
WH3_k127_6664213_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.273e-261 820.0
WH3_k127_6664213_10 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000002925 192.0
WH3_k127_6664213_11 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.000000000000000000000000000000000000000000000000009356 190.0
WH3_k127_6664213_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000006046 161.0
WH3_k127_6664213_13 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000003606 151.0
WH3_k127_6664213_14 Membrane protein insertase, YidC Oxa1 family K03217 - - 0.000000000000000000000000000001245 127.0
WH3_k127_6664213_15 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000004235 132.0
WH3_k127_6664213_16 Could be involved in insertion of integral membrane proteins into the membrane - - - 0.000000000000000000000000001916 113.0
WH3_k127_6664213_17 Polysaccharide deacetylase - - - 0.00000000000000000000000001501 119.0
WH3_k127_6664213_18 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000007388 81.0
WH3_k127_6664213_19 Ribosomal protein L34 K02914 - - 0.000000000003836 68.0
WH3_k127_6664213_2 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 577.0
WH3_k127_6664213_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000365 73.0
WH3_k127_6664213_21 Protein of unknown function (DUF721) - - - 0.0003645 49.0
WH3_k127_6664213_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 469.0
WH3_k127_6664213_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 343.0
WH3_k127_6664213_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 334.0
WH3_k127_6664213_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001843 279.0
WH3_k127_6664213_7 Double zinc ribbon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001505 268.0
WH3_k127_6664213_8 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004371 274.0
WH3_k127_6664213_9 IA, variant 3 K06019 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000005065 216.0
WH3_k127_6693612_0 Efflux ABC transporter permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001016 269.0
WH3_k127_6693612_1 Protein of unknown function (DUF4004) - - - 0.000000000000000000000000000000000000000000000006482 179.0
WH3_k127_6693612_2 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000001447 134.0
WH3_k127_6749599_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 5.845e-196 622.0
WH3_k127_6749599_1 Nicotinamidase K08281 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000007567 250.0
WH3_k127_6749599_2 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001455 237.0
WH3_k127_6749599_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000142 123.0
WH3_k127_6764047_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 451.0
WH3_k127_6764047_1 PilT protein domain protein - - - 0.00000000000001968 78.0
WH3_k127_6780597_0 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000001428 231.0
WH3_k127_6780597_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000007279 213.0
WH3_k127_6780597_10 - - - - 0.00008506 49.0
WH3_k127_6780597_11 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0005459 51.0
WH3_k127_6780597_2 phosphatase activity K07025,K08723,K20862 - 3.1.3.102,3.1.3.104,3.1.3.5 0.00000000000000000000000000000000000000000000143 174.0
WH3_k127_6780597_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000003286 154.0
WH3_k127_6780597_4 - - - - 0.000000000000000000000000000000291 129.0
WH3_k127_6780597_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000005886 122.0
WH3_k127_6780597_6 - - - - 0.000000000000000004399 89.0
WH3_k127_6780597_7 Acetyltransferase (GNAT) K06977 - - 0.0000000000000009066 80.0
WH3_k127_6780597_8 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K03469,K08234 - 3.1.26.4 0.000000000001211 81.0
WH3_k127_6780597_9 Pyruvate formate lyase-like - - - 0.0000000008855 65.0
WH3_k127_6868370_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 390.0
WH3_k127_6868370_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008679 276.0
WH3_k127_6868370_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002045 258.0
WH3_k127_6868370_3 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003661 269.0
WH3_k127_6868370_4 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000457 244.0
WH3_k127_6868370_5 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000001248 228.0
WH3_k127_6878844_0 DNA topoisomerase K03168 - 5.99.1.2 4.129e-251 794.0
WH3_k127_6878844_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 389.0
WH3_k127_6878844_2 Fumarate hydratase (Fumerase) K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007536 284.0
WH3_k127_69165_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 297.0
WH3_k127_69165_1 FeS-containing Cyanobacterial-specific oxidoreductase - - - 0.000000000000000000000000000000000000000006491 160.0
WH3_k127_69165_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000002201 156.0
WH3_k127_6957623_0 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 349.0
WH3_k127_6957623_1 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000001425 226.0
WH3_k127_6957623_2 Crossover junction endodeoxyribonuclease RuvC K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00004721 48.0
WH3_k127_6964991_0 PFAM glycoside hydrolase family 39 - - - 0.0000000000000000000001336 113.0
WH3_k127_6964991_1 Glycosyl transferases group 1 - - - 0.0000000000000000000001922 104.0
WH3_k127_6964991_2 PFAM L,D-transpeptidase catalytic domain - - - 0.000000000000000001951 100.0
WH3_k127_6964991_3 Glycosyl hydrolase family 59 - - - 0.0000000000007665 81.0
WH3_k127_6964991_4 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0001968 54.0
WH3_k127_7020421_0 - - - - 0.0000000000000000000000000000000001084 139.0
WH3_k127_7020421_1 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.0000000000000000000000000000000006663 134.0
WH3_k127_7020421_2 - - - - 0.000000000005564 75.0
WH3_k127_7030865_0 NAD binding domain protein K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 329.0
WH3_k127_7030865_1 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001235 286.0
WH3_k127_7030865_2 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000002674 222.0
WH3_k127_7030865_3 acetyltransferase - - - 0.00000000000000000000000000000000001506 146.0
WH3_k127_7030865_4 WD40-like Beta Propeller Repeat - - - 0.00000000016 74.0
WH3_k127_7058510_0 Putative glucoamylase K13688 - - 0.0 2261.0
WH3_k127_7058510_1 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 441.0
WH3_k127_7058510_2 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000003854 145.0
WH3_k127_7058510_3 Thioredoxin - - - 0.000000000001932 81.0
WH3_k127_7058510_4 F plasmid transfer operon protein - - - 0.000000004025 60.0
WH3_k127_715215_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 459.0
WH3_k127_715215_1 Peptidase, U32 family K08303 - - 0.00000000000000000000000000000000004533 145.0
WH3_k127_7173777_0 type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 510.0
WH3_k127_7173777_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 473.0
WH3_k127_7173777_2 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 324.0
WH3_k127_7173777_3 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 321.0
WH3_k127_7244810_0 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 594.0
WH3_k127_7244810_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 338.0
WH3_k127_7244810_10 Acetyltransferase (GNAT) K06977 - - 0.0000000000000000000000000000000000000282 147.0
WH3_k127_7244810_12 DegV family - - - 0.00000000000000000000000000000000007198 141.0
WH3_k127_7244810_13 ATPases associated with a variety of cellular activities K02006 - - 0.00000000000000000000000003426 112.0
WH3_k127_7244810_14 - - - - 0.0000000000000000000000003319 109.0
WH3_k127_7244810_15 - - - - 0.0000000000000000000000009975 109.0
WH3_k127_7244810_16 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000001666 79.0
WH3_k127_7244810_2 PFAM sodium calcium exchanger membrane region K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008148 263.0
WH3_k127_7244810_3 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000001809 219.0
WH3_k127_7244810_4 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000000005715 202.0
WH3_k127_7244810_5 Anaerobic sulfatase maturase K06871 - - 0.0000000000000000000000000000000000000000000000000000008104 207.0
WH3_k127_7244810_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000009338 171.0
WH3_k127_7244810_7 InterPro IPR014922 - - - 0.00000000000000000000000000000000000000000005863 164.0
WH3_k127_7244810_8 RibD C-terminal domain - - - 0.000000000000000000000000000000000000002697 149.0
WH3_k127_7244810_9 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000217 153.0
WH3_k127_7290151_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 382.0
WH3_k127_7290151_1 It is involved in the biological process described with biosynthetic process - GO:0007275,GO:0007399,GO:0007417,GO:0008150,GO:0032501,GO:0032502,GO:0048731,GO:0048856 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001854 269.0
WH3_k127_7290151_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000001595 254.0
WH3_k127_7290151_3 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000002407 209.0
WH3_k127_7290151_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000003889 206.0
WH3_k127_7290151_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000004426 186.0
WH3_k127_7290151_6 integration host factor - - - 0.0000000000000000000000000000004061 125.0
WH3_k127_7290151_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 0.00000000007996 66.0
WH3_k127_7297861_0 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 364.0
WH3_k127_7297861_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000009327 237.0
WH3_k127_7297861_2 Mediates influx of magnesium ions K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000347 191.0
WH3_k127_7297861_3 ABC transporter K15738 - - 0.0000000000000000000000000000000000000001975 152.0
WH3_k127_7297861_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K00587 - 2.1.1.100 0.0000000003705 66.0
WH3_k127_7330804_0 Clp domain protein K03696 - - 0.0 1151.0
WH3_k127_7330804_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 593.0
WH3_k127_7330804_2 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 369.0
WH3_k127_7330804_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 295.0
WH3_k127_7330804_4 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000001707 225.0
WH3_k127_7330804_5 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000001029 201.0
WH3_k127_7330804_6 transferase activity, transferring alkyl or aryl (other than methyl) groups K22205 - - 0.00000000000000000000000000000000000000000000000002349 189.0
WH3_k127_7330804_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000002577 165.0
WH3_k127_7330804_8 Predicted membrane protein (DUF2085) - - - 0.0000000000000002121 87.0
WH3_k127_7330804_9 mttA/Hcf106 family - - - 0.000000001412 61.0
WH3_k127_7398130_0 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000005312 270.0
WH3_k127_7398130_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000002273 194.0
WH3_k127_7398130_2 Oxidoreductase FAD-binding domain - - - 0.000000000000000001107 97.0
WH3_k127_748965_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 9.664e-200 639.0
WH3_k127_748965_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 513.0
WH3_k127_748965_10 Cytidylate kinase-like family K00760 - 2.4.2.8 0.000000000000000000000000000000000003257 145.0
WH3_k127_748965_11 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000009727 138.0
WH3_k127_748965_12 Fha domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.00000000000000000000000006619 112.0
WH3_k127_748965_13 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000002074 107.0
WH3_k127_748965_15 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000001424 59.0
WH3_k127_748965_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003465 286.0
WH3_k127_748965_3 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001122 276.0
WH3_k127_748965_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000001047 209.0
WH3_k127_748965_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000001158 205.0
WH3_k127_748965_6 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000004128 195.0
WH3_k127_748965_7 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000002734 190.0
WH3_k127_748965_8 NLP P60 protein K21471 - - 0.000000000000000000000000000000000000007829 160.0
WH3_k127_748965_9 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000001404 156.0
WH3_k127_7560273_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000001187 197.0
WH3_k127_7560273_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000046 158.0
WH3_k127_7560273_2 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00009115 53.0
WH3_k127_7560273_3 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0002928 52.0
WH3_k127_7577124_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.67e-257 815.0
WH3_k127_7610467_0 Belongs to the catalase family K03781 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.6 3.117e-272 844.0
WH3_k127_7610467_1 Pyridoxal-phosphate dependent enzyme K21400 - 2.3.1.263 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 589.0
WH3_k127_7610467_10 - K21399 GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 2.3.1.263 0.0000000000000000000001476 102.0
WH3_k127_7610467_11 Predicted permease - - - 0.0000000000002487 80.0
WH3_k127_7610467_12 DNA-binding transcription factor activity K03741,K03892 - 1.20.4.1 0.000000000006545 70.0
WH3_k127_7610467_13 Domain of unknown function (DUF2703) - - - 0.00000000002333 70.0
WH3_k127_7610467_14 cell redox homeostasis K02199,K03671 - - 0.00000007044 56.0
WH3_k127_7610467_2 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 460.0
WH3_k127_7610467_3 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 367.0
WH3_k127_7610467_4 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009399 267.0
WH3_k127_7610467_5 ABC transporter permease K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002915 270.0
WH3_k127_7610467_6 D-Lysine 5,6-aminomutase alpha subunit K17898 - 5.4.3.5 0.00000000000000000000000000000000000001984 151.0
WH3_k127_7610467_7 Predicted permease - - - 0.0000000000000000000000000000000054 133.0
WH3_k127_7610467_8 D-ornithine 4,5-aminomutase alpha-subunit K17899 - 5.4.3.5 0.000000000000000000000000000007584 124.0
WH3_k127_7610467_9 Redox-active disulfide protein - - - 0.000000000000000000000001372 105.0
WH3_k127_7635509_0 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000004895 203.0
WH3_k127_7635509_1 DnaJ molecular chaperone homology domain - - - 0.00004956 48.0
WH3_k127_7635509_2 transcriptional - - - 0.000587 52.0
WH3_k127_7738506_0 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 414.0
WH3_k127_7738506_1 PFAM HI0933 family protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003409 291.0
WH3_k127_7738506_2 Alanine dehydrogenase/PNT, C-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000411 272.0
WH3_k127_7738506_3 FAD dependent oxidoreductase K07137 - - 0.0000000000002053 79.0
WH3_k127_774106_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 518.0
WH3_k127_774106_1 DnaQ family exonuclease DinG family helicase K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 405.0
WH3_k127_774106_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000001632 193.0
WH3_k127_774106_3 overlaps another CDS with the same product name K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000004307 143.0
WH3_k127_774106_5 transcriptional regulator K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000215 126.0
WH3_k127_774106_6 Heavy metal translocating P-type atpase - - - 0.0000000000000000000004519 106.0
WH3_k127_774106_7 helix_turn_helix, cAMP Regulatory protein K21563 - - 0.00000000000000000002141 102.0
WH3_k127_774106_8 - - - - 0.0000000008496 70.0
WH3_k127_7885051_0 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 607.0
WH3_k127_7885051_1 PFAM glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 336.0
WH3_k127_7885051_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000007244 196.0
WH3_k127_7885051_3 PFAM NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000001096 180.0
WH3_k127_7885051_4 GDP-mannose 4,6 dehydratase K01709 - 4.2.1.45 0.00000000001283 68.0
WH3_k127_7918153_0 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000006294 270.0
WH3_k127_7918153_1 Fumarase C-terminus K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000005165 198.0
WH3_k127_7918153_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000004272 186.0
WH3_k127_7918153_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000002702 164.0
WH3_k127_8054032_0 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 363.0
WH3_k127_8054032_1 Proton-conducting membrane transporter K05568,K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 341.0
WH3_k127_8054032_2 PFAM NADH-ubiquinone oxidoreductase chain 4L K05567 - - 0.00000000177 59.0
WH3_k127_8074750_0 EDD domain protein, DegV family - - - 0.000000000000000000000000000000000000000000000000000000000000000007672 229.0
WH3_k127_8074750_1 Protein of unknown function (DUF2089) - - - 0.00000000000000000000000000000000306 135.0
WH3_k127_8074750_2 - - - - 0.00000000000000000000000002959 119.0
WH3_k127_8074750_3 peptidoglycan binding K03642 - - 0.0000000000000006389 89.0
WH3_k127_8074750_4 Transcriptional regulator - - - 0.00000000005244 69.0
WH3_k127_8074750_5 - - - - 0.0000000005207 62.0
WH3_k127_8087677_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 458.0
WH3_k127_8087677_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000001238 145.0
WH3_k127_813116_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 446.0
WH3_k127_813116_1 flavodoxin nitric oxide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 366.0
WH3_k127_813116_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 321.0
WH3_k127_813116_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000685 114.0
WH3_k127_813116_4 copG family - - - 0.0000000000000000000001115 100.0
WH3_k127_813116_5 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00003309 55.0
WH3_k127_8177547_0 ABC transporter K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 350.0
WH3_k127_8177547_1 Substrate binding domain of ABC-type glycine betaine transport system K05845 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0033554,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0104004 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 300.0
WH3_k127_8177547_2 PFAM Binding-protein-dependent transport system inner membrane component K05846 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - 0.000000000000000000000000000000000000000000000000000000000000000000008746 248.0
WH3_k127_8177547_3 PFAM Binding-protein-dependent transport system inner membrane component K05846 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - 0.00000000000000000000000000000002365 134.0
WH3_k127_824240_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1178.0
WH3_k127_824240_1 competence protein ComEC K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000767 273.0
WH3_k127_824240_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000004383 225.0
WH3_k127_824240_3 ComEA protein K02237 - - 0.00000000000000000000000000000000000000036 157.0
WH3_k127_824240_4 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000001374 143.0
WH3_k127_824240_5 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000008426 109.0
WH3_k127_824240_6 Chagasin family peptidase inhibitor I42 K14475 - - 0.00000000000000000823 91.0
WH3_k127_8288798_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003235 248.0
WH3_k127_8288798_2 Winged helix DNA-binding domain K22296 - - 0.00000000008036 68.0
WH3_k127_8288798_3 Psort location Cytoplasmic, score - - - 0.000003014 53.0
WH3_k127_8292096_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 486.0
WH3_k127_8292096_1 PFAM SufBD protein K07033,K09014,K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 457.0
WH3_k127_8292096_2 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 290.0
WH3_k127_8292096_3 endonuclease III K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006543 282.0
WH3_k127_8292096_4 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002056 273.0
WH3_k127_8292096_5 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000005805 282.0
WH3_k127_8292096_6 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000005531 197.0
WH3_k127_8292096_7 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000004349 190.0
WH3_k127_8292096_8 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000001234 178.0
WH3_k127_8292096_9 - K15383 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0042802,GO:0044425 - 0.000001243 56.0
WH3_k127_8303410_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 517.0
WH3_k127_8303410_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0008150,GO:0040007 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 488.0
WH3_k127_8303410_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 332.0
WH3_k127_8303410_3 TIGRFAM cell envelope-related function transcriptional attenuator - - - 0.00000000000000000000000000000000000000000000000000000002109 214.0
WH3_k127_8303410_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000003327 179.0
WH3_k127_8303410_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000006754 121.0
WH3_k127_8303410_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000003671 113.0
WH3_k127_8303410_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00000000000000000006451 89.0
WH3_k127_8303410_8 Transposase IS66 family - - - 0.00000003902 57.0
WH3_k127_8330931_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.273e-221 694.0
WH3_k127_8330931_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 574.0
WH3_k127_8330931_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000009197 190.0
WH3_k127_8330931_3 metallopeptidase activity - - - 0.000000000000000000000000000000000000000283 153.0
WH3_k127_8330931_4 Peptidase family M28 - - - 0.000000000000000000000000000003205 132.0
WH3_k127_8349954_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 8.562e-298 922.0
WH3_k127_8389069_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 535.0
WH3_k127_8389069_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000003533 162.0
WH3_k127_8389069_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.00000000000000000000000000000000002523 148.0
WH3_k127_8389069_3 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000001371 139.0
WH3_k127_8449623_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.955e-247 774.0
WH3_k127_8449623_1 ABC transporter, ATP-binding protein K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 562.0
WH3_k127_8449623_10 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000002221 121.0
WH3_k127_8449623_11 integral membrane protein MviN K03980 - - 0.000000001756 60.0
WH3_k127_8449623_2 Peptidase dimerisation domain K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 325.0
WH3_k127_8449623_3 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 328.0
WH3_k127_8449623_4 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 289.0
WH3_k127_8449623_5 Protein of unknown function (DUF3866) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001436 290.0
WH3_k127_8449623_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003952 289.0
WH3_k127_8449623_7 Basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001497 282.0
WH3_k127_8449623_8 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000009168 192.0
WH3_k127_8449623_9 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan - - - 0.000000000000000000000000006543 127.0
WH3_k127_847762_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 334.0
WH3_k127_847762_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000005888 214.0
WH3_k127_847762_2 Acyltransferase K00655 - 2.3.1.51 0.00005759 54.0
WH3_k127_8483674_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 473.0
WH3_k127_8483674_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 384.0
WH3_k127_8483674_10 Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain K04771 GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 0.0000000000000000000003663 112.0
WH3_k127_8483674_11 Belongs to the peptidase M48B family K03799 - - 0.000000000002091 79.0
WH3_k127_8483674_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 347.0
WH3_k127_8483674_3 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 370.0
WH3_k127_8483674_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 295.0
WH3_k127_8483674_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000003392 230.0
WH3_k127_8483674_6 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000006542 228.0
WH3_k127_8483674_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
WH3_k127_8483674_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000009781 225.0
WH3_k127_8483674_9 PFAM Pyridoxamine 5'-phosphate oxidase-related K07005 - - 0.0000000000000000000000000001492 129.0
WH3_k127_8561900_0 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 385.0
WH3_k127_8561900_1 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.00000000000000000000000000000000000000000000001476 179.0
WH3_k127_8568012_0 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 389.0
WH3_k127_8568012_1 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 321.0
WH3_k127_8568012_2 tRNA (guanine-N7-)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000003899 201.0
WH3_k127_8568012_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000003905 106.0
WH3_k127_8568012_4 FIST N domain - - - 0.00001857 51.0
WH3_k127_8603581_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 593.0
WH3_k127_8603581_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 555.0
WH3_k127_8603581_2 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003233 273.0
WH3_k127_8603581_3 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000001205 151.0
WH3_k127_8603581_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000001754 111.0
WH3_k127_8632944_0 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000000000007383 179.0
WH3_k127_8632944_1 - - - - 0.000000000000000000000000000000000000000000002146 173.0
WH3_k127_8632944_2 HNH endonuclease - - - 0.0000000000000000000000000000009116 124.0
WH3_k127_8632944_3 nucleic acid-binding protein contains PIN domain - - - 0.0008576 48.0
WH3_k127_863810_0 DNA helicase K03657 - 3.6.4.12 1.601e-231 738.0
WH3_k127_863810_1 DHHA2 K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 421.0
WH3_k127_863810_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008783 276.0
WH3_k127_863810_3 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000471 268.0
WH3_k127_863810_4 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000012 247.0
WH3_k127_863810_5 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000001502 201.0
WH3_k127_863810_6 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000005154 92.0
WH3_k127_863810_7 COG0581 ABC-type phosphate transport system permease component K02038 - - 0.00001508 53.0
WH3_k127_8685653_0 PFAM major facilitator superfamily MFS_1 K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 372.0
WH3_k127_8685653_1 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003138 287.0
WH3_k127_8685653_2 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000601 228.0
WH3_k127_8685653_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.00000000000000000000000000000000000000000000000000000001007 202.0
WH3_k127_8685653_4 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000001541 204.0
WH3_k127_8685653_5 thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000352 173.0
WH3_k127_8685653_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000001316 139.0
WH3_k127_8685653_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000002906 65.0
WH3_k127_8800999_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000002302 162.0
WH3_k127_8820571_0 Amidinotransferase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 505.0
WH3_k127_8820571_1 Belongs to the bacterial solute-binding protein 3 family K10039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 296.0
WH3_k127_8820571_2 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K10040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001843 269.0
WH3_k127_8820571_3 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K09971,K10040 - - 0.0000000000000000000000000000000000000000000000000000000298 203.0
WH3_k127_8869895_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.184e-227 711.0
WH3_k127_8869895_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K00972 - 2.7.7.23,2.7.7.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 487.0
WH3_k127_8869895_2 Glucosamine-6-phosphate deaminase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 435.0
WH3_k127_8869895_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000002297 282.0
WH3_k127_8869895_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000167 189.0
WH3_k127_8869895_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000001896 158.0
WH3_k127_8869895_6 PFAM CBS domain - - - 0.00000000000000000000000000002918 124.0
WH3_k127_8885471_0 SMART zinc finger, CDGSH-type domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002831 259.0
WH3_k127_8885471_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000003172 234.0
WH3_k127_8885471_2 Sulfate permease family K03321 GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000002525 152.0
WH3_k127_8889390_0 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 336.0
WH3_k127_8889390_1 PHP domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002564 284.0
WH3_k127_8889390_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000004301 175.0
WH3_k127_8889390_3 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000008809 128.0
WH3_k127_8910829_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 517.0
WH3_k127_8910829_1 Cupin domain K15546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002939 265.0
WH3_k127_8910829_2 PFAM Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000009825 138.0
WH3_k127_8910829_3 - - - - 0.00000001839 64.0
WH3_k127_8963370_0 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 427.0
WH3_k127_8963370_1 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 359.0
WH3_k127_8963370_2 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003101 296.0
WH3_k127_8963370_3 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001346 285.0
WH3_k127_8963370_4 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000004422 83.0
WH3_k127_9006795_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 448.0
WH3_k127_9006795_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 417.0
WH3_k127_9006795_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000002818 189.0
WH3_k127_9006795_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000009719 157.0
WH3_k127_9128318_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 327.0
WH3_k127_9128318_1 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000002425 242.0
WH3_k127_9128318_2 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000001558 149.0
WH3_k127_9128318_3 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000005972 137.0
WH3_k127_9128318_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000002219 117.0
WH3_k127_9128318_5 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000195 86.0
WH3_k127_9133280_0 PFAM AAA ATPase central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 336.0
WH3_k127_9133280_1 RNA polymerase sigma-70 factor, sigma-B F G subfamily K03090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 295.0
WH3_k127_9133280_2 - K04757 - 2.7.11.1 0.00000000000000005435 86.0
WH3_k127_9263455_0 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 597.0
WH3_k127_9263455_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 498.0
WH3_k127_9263455_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000073 136.0
WH3_k127_9345540_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 470.0
WH3_k127_9345540_1 TIGRFAM Arsenical-resistance protein K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 451.0
WH3_k127_9345540_2 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000002281 209.0
WH3_k127_9345540_3 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000003356 87.0
WH3_k127_9345540_4 regulatory protein, arsR - - - 0.0000000000000000007453 89.0
WH3_k127_9368406_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 487.0
WH3_k127_9368406_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000256 243.0
WH3_k127_9368406_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000007339 241.0
WH3_k127_9368406_3 PFAM sigma-70 region 2 domain protein K03091 - - 0.00000000000000000000000000000000000000000000000000000000000000006733 230.0
WH3_k127_9368406_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000002648 212.0
WH3_k127_9368406_5 cyclic nucleotide binding K09766,K10914 - - 0.000000000000000000000006339 106.0
WH3_k127_9368406_6 YacP-like NYN domain K06962 - - 0.0000000121 64.0
WH3_k127_9368406_7 protein folding in endoplasmic reticulum K19134 - - 0.000000671 59.0
WH3_k127_9368406_8 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00004421 56.0
WH3_k127_9372632_0 Cys/Met metabolism PLP-dependent enzyme K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 476.0
WH3_k127_9372632_1 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002592 271.0
WH3_k127_9372632_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000001691 236.0
WH3_k127_9372632_3 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000007339 215.0
WH3_k127_9372632_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000000000000000000000000000000000000000002612 193.0
WH3_k127_9372632_5 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000005691 153.0
WH3_k127_9372632_6 - - - - 0.0000000000000000000004091 105.0
WH3_k127_9372632_7 Acyltransferase K02517 - 2.3.1.241 0.00000007831 63.0
WH3_k127_9399778_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000000000000000007369 198.0
WH3_k127_9399778_1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K11618 - - 0.00000000000003669 81.0
WH3_k127_9399778_2 Histidine kinase - - - 0.000000000001415 81.0
WH3_k127_9399778_3 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000411 72.0
WH3_k127_9489517_0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 532.0
WH3_k127_9489517_1 PFAM Glycosyl transferase, group 1 K06338,K12995 - 2.4.1.348 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006452 290.0
WH3_k127_9489517_10 NHL repeat - - - 0.00000002824 62.0
WH3_k127_9489517_2 sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008791 275.0
WH3_k127_9489517_3 ABC transporter, transmembrane region K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002749 271.0
WH3_k127_9489517_4 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000003743 205.0
WH3_k127_9489517_5 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000002416 193.0
WH3_k127_9489517_6 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000001428 169.0
WH3_k127_9489517_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790 - 1.1.1.133,5.1.3.13 0.000000000000000000001021 101.0
WH3_k127_9489517_8 O-Antigen ligase - - - 0.000000000007395 79.0
WH3_k127_9489517_9 Tetratricopeptide repeat - - - 0.000000007554 66.0
WH3_k127_9500674_0 Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 426.0
WH3_k127_9500674_1 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 371.0
WH3_k127_9500674_2 Neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 358.0
WH3_k127_9500674_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 308.0
WH3_k127_9500674_4 denitrification pathway - - - 0.00000000000000000000000473 116.0
WH3_k127_9500674_5 Polymer-forming cytoskeletal - - - 0.000000000009055 66.0
WH3_k127_9592514_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000001611 136.0
WH3_k127_9592514_1 - - - - 0.0000000000003722 82.0
WH3_k127_9592514_2 NADH dehydrogenase ubiquinone iron-sulfur protein 7 K03940 GO:0000302,GO:0002118,GO:0002121,GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0007275,GO:0007568,GO:0007610,GO:0008150,GO:0008152,GO:0008340,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010257,GO:0010259,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048856,GO:0050789,GO:0050794,GO:0050803,GO:0050807,GO:0050896,GO:0051128,GO:0051704,GO:0051705,GO:0055086,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0099174,GO:1901135,GO:1901360,GO:1901564,GO:1901700,GO:1902494,GO:1990204,GO:2000331 1.6.5.3,1.6.99.3 0.000000008829 64.0
WH3_k127_9611494_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 490.0
WH3_k127_9611494_1 Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP K05716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 368.0
WH3_k127_9611494_2 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 294.0
WH3_k127_9611494_3 PFAM Glycosyl transferase family 2 K00752,K11936 - 2.4.1.212 0.00000000000000000000000000000000000000000000000000000000003157 217.0
WH3_k127_9611494_4 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000000000000000000003339 198.0
WH3_k127_9611494_5 2-phosphoglycerate kinase K05715 - - 0.00000000000000000000000000005119 127.0
WH3_k127_9617007_0 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571 - 4.1.1.3 7.803e-224 704.0
WH3_k127_9617007_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 594.0
WH3_k127_9617007_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 309.0
WH3_k127_9617007_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000001085 144.0
WH3_k127_9617007_4 Asp23 family, cell envelope-related function - - - 0.00000002659 62.0
WH3_k127_9617007_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0003502 49.0
WH3_k127_9629139_0 Threonine synthase K01733 - 4.2.3.1 4.032e-197 629.0
WH3_k127_9629139_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 632.0
WH3_k127_9629139_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 610.0
WH3_k127_9629139_3 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 354.0
WH3_k127_9661600_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.997e-243 759.0
WH3_k127_9661600_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000003135 103.0
WH3_k127_9671071_0 copper-translocating P-type ATPase K01533 - 3.6.3.4 3.581e-214 677.0
WH3_k127_9671071_1 Adenylosuccinate lyase C-terminus K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 449.0
WH3_k127_9671071_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000001083 124.0
WH3_k127_9677341_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.397e-290 911.0
WH3_k127_9677341_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 434.0
WH3_k127_9677341_10 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000005538 170.0
WH3_k127_9677341_11 PFAM AzlC - - - 0.00000000000000000000000000000000000000007986 159.0
WH3_k127_9677341_12 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000000000566 114.0
WH3_k127_9677341_13 - - - - 0.00000000000000000007335 93.0
WH3_k127_9677341_14 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000008958 83.0
WH3_k127_9677341_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 332.0
WH3_k127_9677341_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 299.0
WH3_k127_9677341_4 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001055 290.0
WH3_k127_9677341_5 FAD binding domain K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002214 286.0
WH3_k127_9677341_6 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000006779 251.0
WH3_k127_9677341_7 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000001078 231.0
WH3_k127_9677341_8 proteolysis - - - 0.00000000000000000000000000000000000000000000000000000000001358 213.0
WH3_k127_9677341_9 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000000000000306 190.0
WH3_k127_9698478_0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000000214 125.0
WH3_k127_9698478_1 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.00000000000000000000000002602 120.0
WH3_k127_9698478_2 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05564,K05571 - - 0.0000000000000000000659 102.0
WH3_k127_9698478_3 Domain of unknown function (DUF4040) - - - 0.0000000000000000002098 89.0
WH3_k127_9698478_4 Na+/H+ ion antiporter subunit K05569 - - 0.0000000000000000002788 94.0
WH3_k127_9698478_5 protein, Hemolysin III K11068 - - 0.0000000000000000004713 88.0
WH3_k127_9698478_6 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.0000000000000002073 81.0
WH3_k127_9698478_7 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000005719 67.0
WH3_k127_9760294_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 402.0
WH3_k127_9760294_1 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 367.0
WH3_k127_9760294_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 338.0
WH3_k127_9760294_3 phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005882 276.0
WH3_k127_9760294_4 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000000000000008821 167.0
WH3_k127_9760294_5 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000004326 137.0
WH3_k127_9821722_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 428.0
WH3_k127_9821722_1 Domain of unknown function (DUF362) K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 416.0
WH3_k127_9821722_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000006293 259.0
WH3_k127_9821722_3 TIGRFAM looped-hinge helix DNA binding domain, AbrB family K06284 - - 0.00000000000000000000008093 104.0
WH3_k127_9821722_4 - - - - 0.00000000001968 76.0
WH3_k127_9928723_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 454.0
WH3_k127_9928723_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 454.0
WH3_k127_9928723_10 Lysin motif - - - 0.0001298 49.0
WH3_k127_9928723_2 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 367.0
WH3_k127_9928723_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 298.0
WH3_k127_9928723_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003893 289.0
WH3_k127_9928723_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000005253 251.0
WH3_k127_9928723_6 permease K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000004192 243.0
WH3_k127_9928723_7 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000002478 201.0
WH3_k127_9928723_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000003068 195.0
WH3_k127_9928723_9 Anaerobic ribonucleoside-triphosphate reductase - - - 0.000003884 52.0
WH3_k127_9957085_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 2.841e-260 827.0
WH3_k127_9957085_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 479.0
WH3_k127_9957085_10 Peptidase S24-like K13280 - 3.4.21.89 0.000000002604 67.0
WH3_k127_9957085_11 Regulates arginine biosynthesis genes K03402 - - 0.00000001674 64.0
WH3_k127_9957085_12 Camelysin metallo-endopeptidase - - - 0.000006265 54.0
WH3_k127_9957085_2 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 383.0
WH3_k127_9957085_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 378.0
WH3_k127_9957085_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 342.0
WH3_k127_9957085_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 306.0
WH3_k127_9957085_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 306.0
WH3_k127_9957085_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000002836 186.0
WH3_k127_9957085_8 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000891 94.0
WH3_k127_9957085_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000001698 87.0
WH3_k127_9968478_0 GTP-binding protein TypA K06207 - - 3.818e-210 661.0
WH3_k127_9968478_1 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.000000000000000000000000000000000000000000000000000000009016 207.0
WH3_k127_9968478_2 Arsenical pump membrane protein - - - 0.00000001467 61.0