logo

Overview

ID MAG04165
Name WH3_bin.56
Sample SMP0108
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Sphingomonadales
Family Sphingomonadaceae
Genus Allopontixanthobacter
Species
Assembly information
Completeness (%) 71.32
Contamination (%) 2.58
GC content (%) 62.0
N50 (bp) 4,392
Genome size (bp) 1,787,835

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2011

Gene name Description KEGG GOs EC E-value Score Sequence
WH3_k127_10039122_0 glutamate--cysteine ligase K01919 - 6.3.2.2 1.853e-261 810.0
WH3_k127_10039122_1 protein-S-isoprenylcysteine methyltransferase - - - 1.377e-211 665.0
WH3_k127_10039122_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 448.0
WH3_k127_10039122_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 368.0
WH3_k127_10039122_4 Pyrrolo-quinoline quinone - - - 0.0000000000000000000000000000000000000000000000000000000000002657 213.0
WH3_k127_10048096_0 Melibiase K07407 - 3.2.1.22 1.662e-227 725.0
WH3_k127_10048096_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.667e-223 704.0
WH3_k127_10048096_2 Aldolase K01631 - 4.1.2.21 0.000000000000000000000000000000000000000001205 160.0
WH3_k127_10048096_3 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0000000000004776 71.0
WH3_k127_10069825_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 9.4e-323 993.0
WH3_k127_10069825_1 Domain of unknown function (DUF389) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 584.0
WH3_k127_10069825_2 Regulatory protein RecX K03565 - - 0.000000000000000000000000000000000000000000000000007788 190.0
WH3_k127_10069825_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000007844 62.0
WH3_k127_10089746_0 Domain of unknown function (DUF305) - - - 1.441e-300 931.0
WH3_k127_10089746_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 591.0
WH3_k127_10104916_0 aminopeptidase N K01256 - 3.4.11.2 1.116e-278 865.0
WH3_k127_10104916_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.622e-195 610.0
WH3_k127_10104916_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 325.0
WH3_k127_10104916_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 320.0
WH3_k127_10122400_0 Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 607.0
WH3_k127_10122400_1 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 477.0
WH3_k127_10122400_2 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001814 273.0
WH3_k127_10140181_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 9.012e-215 677.0
WH3_k127_10140181_1 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 462.0
WH3_k127_10140181_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 434.0
WH3_k127_10140181_3 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 402.0
WH3_k127_10140181_4 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000002351 190.0
WH3_k127_10143070_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 2.389e-261 808.0
WH3_k127_10143070_1 Protein of unknown function (DUF2855) - - - 0.00000000000000000002029 92.0
WH3_k127_10189742_0 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 472.0
WH3_k127_10189742_1 Protein of unknown function (DUF2726) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001132 274.0
WH3_k127_10200363_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1522.0
WH3_k127_10200363_1 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 355.0
WH3_k127_10200363_2 - - - - 0.000000000000000003588 93.0
WH3_k127_10246773_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 1.562e-257 814.0
WH3_k127_10246773_1 Sulfate transporter K03321 - - 1.841e-199 629.0
WH3_k127_10246773_2 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 312.0
WH3_k127_10246773_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000008005 243.0
WH3_k127_10246773_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000005157 234.0
WH3_k127_10246773_5 - - - - 0.00000000000000000003153 93.0
WH3_k127_10246773_6 Belongs to the UPF0235 family K09131 - - 0.0000000000000307 76.0
WH3_k127_10351908_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1177.0
WH3_k127_10351908_1 Alkaline phosphatase K01113 - 3.1.3.1 1.985e-206 655.0
WH3_k127_10351908_3 membrane transporter protein K07090 - - 0.000000000000000000811 94.0
WH3_k127_10360945_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.332e-261 813.0
WH3_k127_10360945_1 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 415.0
WH3_k127_10360945_2 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 413.0
WH3_k127_10360945_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 402.0
WH3_k127_10360945_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 369.0
WH3_k127_10360945_5 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000000000001352 139.0
WH3_k127_10438047_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.76e-231 722.0
WH3_k127_10438047_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 532.0
WH3_k127_10438047_2 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 374.0
WH3_k127_10438047_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 347.0
WH3_k127_10438047_4 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000000009142 140.0
WH3_k127_10457072_0 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 551.0
WH3_k127_10457072_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000001223 159.0
WH3_k127_10457072_2 - - - - 0.00000000000000000000000005288 108.0
WH3_k127_10478216_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.369e-320 991.0
WH3_k127_10478216_1 oxygenase K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 312.0
WH3_k127_10478216_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000823 267.0
WH3_k127_10478216_3 Outer membrane protein (OmpH-like) - - - 0.00000000000000000000000000000000000000000000000000004296 195.0
WH3_k127_10478216_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000000002761 148.0
WH3_k127_10478216_5 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000000000000000005873 145.0
WH3_k127_10499375_0 Glyoxalase bleomycin resistance protein dioxygenase K16049 - 1.13.11.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 500.0
WH3_k127_10499375_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 326.0
WH3_k127_10499375_2 Acyl-CoA dehydrogenase, C-terminal domain K16047 - 1.14.14.12 0.000000000000000000000000000000000000000000000000000000000000000000001154 243.0
WH3_k127_10499375_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.000000000000000000000001458 104.0
WH3_k127_10499375_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 0.0000000000000000001362 89.0
WH3_k127_10499375_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000002593 79.0
WH3_k127_1050690_0 DEAD DEAH box helicase K11927 - 3.6.4.13 2.098e-194 619.0
WH3_k127_1050690_1 Polynucleotide adenylyltransferase K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 520.0
WH3_k127_1050690_2 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 493.0
WH3_k127_1050690_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 295.0
WH3_k127_1050690_4 protein conserved in bacteria K09986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002682 273.0
WH3_k127_1050690_5 Acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000668 253.0
WH3_k127_1050690_6 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005879 245.0
WH3_k127_1050690_7 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000000000000000000000000000000002149 158.0
WH3_k127_1050690_8 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.00000000000000000000000000009575 116.0
WH3_k127_10542206_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 323.0
WH3_k127_10542206_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000002133 132.0
WH3_k127_10542206_2 - - - - 0.00000000000000000000000000000004322 129.0
WH3_k127_10542206_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000009989 53.0
WH3_k127_10585307_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.528e-232 722.0
WH3_k127_10585307_1 thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 330.0
WH3_k127_10585307_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 321.0
WH3_k127_10585307_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000005379 237.0
WH3_k127_10585307_4 Acetyltransferase (GNAT) domain K22479 - - 0.00000000000000000000000000000000000000000000000000000000000000000009155 235.0
WH3_k127_10585307_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000000000001335 207.0
WH3_k127_10585307_6 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000000000000000002756 196.0
WH3_k127_10605339_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 544.0
WH3_k127_10605339_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 344.0
WH3_k127_10605339_2 COG0655 Multimeric flavodoxin WrbA - - - 0.000000000000000000000000000000000000000000000000000000003351 201.0
WH3_k127_10605339_3 - - - - 0.000000000000000000000000000000000000000000000000000458 194.0
WH3_k127_10619309_0 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 600.0
WH3_k127_10619309_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 383.0
WH3_k127_10619309_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000001549 73.0
WH3_k127_10619879_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 364.0
WH3_k127_10619879_1 membrane metal-binding protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 321.0
WH3_k127_10619879_2 molybdopterin biosynthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009878 277.0
WH3_k127_10638835_0 Protein of unknown function (DUF3604) - - - 9.439e-287 893.0
WH3_k127_10638835_1 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002023 267.0
WH3_k127_10638835_2 Belongs to the universal stress protein A family - - - 0.0000000000000000006343 87.0
WH3_k127_10638835_3 HupE / UreJ protein - - - 0.00000000007374 69.0
WH3_k127_10638863_0 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000002737 234.0
WH3_k127_10638863_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000004708 166.0
WH3_k127_10638863_2 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0000000000000000000000000006116 115.0
WH3_k127_10646118_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 1.299e-208 655.0
WH3_k127_10646118_1 Protein of unknown function (DUF1153) - - - 0.00000000000000000000000000000000000000000000000000008262 187.0
WH3_k127_10646118_2 Transglycosylase associated protein - - - 0.000000000000000000000000000000000000001441 148.0
WH3_k127_10646118_3 - - - - 0.00000000134 61.0
WH3_k127_10646118_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000005947 51.0
WH3_k127_10661955_0 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 1.596e-222 693.0
WH3_k127_10661955_1 Belongs to the GMC oxidoreductase family - - - 1.222e-218 691.0
WH3_k127_10661955_10 - - - - 0.00000000000000000000005738 104.0
WH3_k127_10661955_2 sterol desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 519.0
WH3_k127_10661955_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 508.0
WH3_k127_10661955_4 Cold shock K03704 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 352.0
WH3_k127_10661955_5 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000898 271.0
WH3_k127_10661955_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000000000002731 256.0
WH3_k127_10661955_7 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005468 243.0
WH3_k127_10661955_8 Protein of unknown function (DUF3035) - - - 0.00000000000000000000000000000000000000000000000000000002171 201.0
WH3_k127_10661955_9 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000003374 165.0
WH3_k127_10670389_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 377.0
WH3_k127_10670389_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 339.0
WH3_k127_10670389_2 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 312.0
WH3_k127_10703279_0 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 569.0
WH3_k127_10703279_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 547.0
WH3_k127_10703279_2 protein conserved in bacteria - - - 0.0000009623 61.0
WH3_k127_10727774_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 477.0
WH3_k127_10727774_1 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000000000000000000000002319 192.0
WH3_k127_10727774_2 beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000004867 139.0
WH3_k127_10748697_0 TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 340.0
WH3_k127_10748697_1 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001444 249.0
WH3_k127_10748697_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000007396 188.0
WH3_k127_10748697_3 acyl carrier protein - - - 0.000000000000000000000000000004646 119.0
WH3_k127_10759774_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.016e-316 980.0
WH3_k127_10759774_1 belongs to the aldehyde dehydrogenase family - - - 8.489e-274 847.0
WH3_k127_10759774_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 421.0
WH3_k127_10759774_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 299.0
WH3_k127_10759774_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.0000000000000000000000000000000004994 131.0
WH3_k127_10759774_5 - - - - 0.000000000000000000000000000000268 129.0
WH3_k127_10759774_6 - - - - 0.00000000000000002467 84.0
WH3_k127_10759774_7 - - - - 0.0000000000000003562 80.0
WH3_k127_10773813_0 Lysophospholipase K01048 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 483.0
WH3_k127_10773813_1 Pilus assembly protein CpaB K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 448.0
WH3_k127_10773813_2 peptidase K02278 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000002779 241.0
WH3_k127_10773813_3 Oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000119 163.0
WH3_k127_10773813_4 Belongs to the GSP D family K02280 - - 0.0000000000000000108 86.0
WH3_k127_10828778_0 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane K11103 - - 2.02e-222 696.0
WH3_k127_10828778_1 Sigma-54 interaction domain K10126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 490.0
WH3_k127_10828778_2 His Kinase A (phosphoacceptor) domain K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 473.0
WH3_k127_10828778_3 His Kinase A (phosphoacceptor) domain K10125 - 2.7.13.3 0.000000000000000000000000000000000000000325 153.0
WH3_k127_10829739_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 350.0
WH3_k127_10829739_1 succinate dehydrogenase K00241 - - 0.000000000000000000000000001202 121.0
WH3_k127_10858855_0 Bacterial protein of unknown function (DUF839) K07093 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 607.0
WH3_k127_10858855_1 6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001115 281.0
WH3_k127_10858855_2 membrane - - - 0.000000000000000000000000000000000000000000001348 171.0
WH3_k127_10858855_3 NUDIX domain - - - 0.0000000000000000000000000000000000000000000182 167.0
WH3_k127_10858855_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000005117 154.0
WH3_k127_10859070_0 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 0.0 1096.0
WH3_k127_10859070_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 482.0
WH3_k127_10859070_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000491 258.0
WH3_k127_10859070_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000002084 237.0
WH3_k127_10859070_4 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000000000000000000000000001128 152.0
WH3_k127_10900648_0 Threonine synthase K01733 - 4.2.3.1 2.067e-234 730.0
WH3_k127_10932182_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 1.271e-203 646.0
WH3_k127_10932182_1 Belongs to the GARS family K01945 - 6.3.4.13 2.314e-203 640.0
WH3_k127_10932182_2 Belongs to the RNase T2 family K01166 - 3.1.27.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 301.0
WH3_k127_10932182_3 Esterase-like activity of phytase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008243 282.0
WH3_k127_10932182_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001993 270.0
WH3_k127_10932182_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000000268 231.0
WH3_k127_10932182_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000000000000001992 168.0
WH3_k127_10932182_7 - - - - 0.000000000000000000000006598 106.0
WH3_k127_10932182_8 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.00000000000000000000003926 100.0
WH3_k127_10955100_0 Alkaline phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 587.0
WH3_k127_10961661_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.176e-237 738.0
WH3_k127_10961661_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 7.016e-225 703.0
WH3_k127_10961661_10 - - - - 0.000000000000000000000000000000000000000000000000000001256 198.0
WH3_k127_10961661_11 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.00000000000000002656 82.0
WH3_k127_10961661_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 606.0
WH3_k127_10961661_3 epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 559.0
WH3_k127_10961661_4 Membrane-bound metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 413.0
WH3_k127_10961661_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 342.0
WH3_k127_10961661_6 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004852 278.0
WH3_k127_10961661_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000001613 240.0
WH3_k127_10961661_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000000005591 199.0
WH3_k127_10961661_9 Disulfide bond formation protein - - - 0.00000000000000000000000000000000000000000000000000000006346 200.0
WH3_k127_10966450_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 376.0
WH3_k127_10966450_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 292.0
WH3_k127_10966450_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001817 269.0
WH3_k127_10966450_3 DNA polymerase III K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000001482 186.0
WH3_k127_10966450_4 protein conserved in bacteria - - - 0.000000000000000005855 85.0
WH3_k127_10969488_0 Penicillin-binding Protein K05515 - 3.4.16.4 1.246e-246 771.0
WH3_k127_10969488_1 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 409.0
WH3_k127_10969488_2 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000007423 219.0
WH3_k127_10969488_3 rod shape-determining protein MreB K03569 - - 0.0000000000000000000001267 96.0
WH3_k127_10975456_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 3.47e-217 680.0
WH3_k127_10975456_1 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.000000000000000000000000000000000000000000000000000000000000000001893 229.0
WH3_k127_10987490_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.0 1147.0
WH3_k127_10987490_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 531.0
WH3_k127_10987490_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000002467 136.0
WH3_k127_10987490_3 Major facilitator Superfamily - - - 0.00000000000000000000000000005979 117.0
WH3_k127_11061280_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 2.191e-266 823.0
WH3_k127_11061280_1 Peptidase, M16 K07263 - - 6.324e-238 746.0
WH3_k127_11061280_2 DinB superfamily - - - 2.713e-201 634.0
WH3_k127_11061280_3 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 514.0
WH3_k127_11061280_4 Flavin containing amine oxidoreductase K06955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 314.0
WH3_k127_11065297_0 of ABC transporters with duplicated ATPase K15738 - - 1.986e-304 940.0
WH3_k127_11065297_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.838e-245 764.0
WH3_k127_11065297_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 507.0
WH3_k127_11065297_3 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 506.0
WH3_k127_11065297_4 XRE family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 304.0
WH3_k127_11065297_5 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002236 252.0
WH3_k127_11065297_6 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002432 233.0
WH3_k127_11106002_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.125e-255 791.0
WH3_k127_11106002_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 413.0
WH3_k127_11106002_2 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000000000000000004899 176.0
WH3_k127_11138616_0 peptidase S9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 476.0
WH3_k127_1114451_0 Dehydrogenase E1 component K11381,K21416 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 496.0
WH3_k127_1114451_1 Dehydrogenase E1 component K00161,K00166,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 449.0
WH3_k127_1114451_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000362 105.0
WH3_k127_1114451_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000001053 93.0
WH3_k127_11166734_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1504.0
WH3_k127_11166734_1 Belongs to the AAA ATPase family K13525 - - 0.0 1327.0
WH3_k127_11166734_2 CHASE3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 475.0
WH3_k127_11166734_3 beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 441.0
WH3_k127_11166734_4 Small-conductance mechanosensitive channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 431.0
WH3_k127_11189295_0 Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 459.0
WH3_k127_11189295_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 454.0
WH3_k127_11189295_2 Resolvase - - - 0.00000000001648 64.0
WH3_k127_11192196_0 Nitrogen fixation protein fixG - - - 5.217e-251 782.0
WH3_k127_11192196_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 409.0
WH3_k127_11192196_2 P-type ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 355.0
WH3_k127_11192196_3 Integral membrane protein linked to a cation - - - 0.000000000000000000000000000000000000106 146.0
WH3_k127_11207167_0 cystathionine beta-lyase K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 417.0
WH3_k127_11207167_1 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000001326 149.0
WH3_k127_11230206_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 4.372e-234 733.0
WH3_k127_11230206_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 568.0
WH3_k127_11230206_2 lipid kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 396.0
WH3_k127_11230206_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 388.0
WH3_k127_11230206_4 Heparinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 362.0
WH3_k127_11230206_5 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 340.0
WH3_k127_11230206_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000188 224.0
WH3_k127_11234281_0 Phage conserved hypothetical protein BR0599 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 346.0
WH3_k127_11234281_1 Putative phage tail protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007965 256.0
WH3_k127_11234281_2 NLP P60 protein - - - 0.00000000000000000000000000000001333 131.0
WH3_k127_11234281_3 Conserved hypothetical protein 2217 (DUF2460) - - - 0.00000000000000000000000004343 108.0
WH3_k127_11249972_0 receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 455.0
WH3_k127_11249972_1 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000004671 108.0
WH3_k127_11271915_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 464.0
WH3_k127_11271915_1 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 410.0
WH3_k127_11371620_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 2.371e-215 673.0
WH3_k127_11371620_1 chorismate mutase K04782 - 4.2.99.21 0.000000000000000000000000000000002343 132.0
WH3_k127_11371620_2 membrane transporter protein K07090 - - 0.000000000000000000000004499 104.0
WH3_k127_11384132_0 isomerase K01809 - 5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 336.0
WH3_k127_11384132_1 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000009465 81.0
WH3_k127_11384132_2 Protein of unknown function (DUF2721) - - - 0.00007463 45.0
WH3_k127_11400921_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 420.0
WH3_k127_11400921_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 413.0
WH3_k127_11408701_0 Major facilitator superfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 506.0
WH3_k127_11408701_1 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 421.0
WH3_k127_11408701_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 329.0
WH3_k127_11446182_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 6.965e-272 841.0
WH3_k127_11446182_1 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 552.0
WH3_k127_11446182_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 503.0
WH3_k127_11446182_3 Peptidyl-prolyl cis-trans - - - 0.000000000000000000000000000000000000000000000000000000009476 204.0
WH3_k127_11446182_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000003545 179.0
WH3_k127_11466398_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 4.742e-230 727.0
WH3_k127_11466398_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 560.0
WH3_k127_11466398_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000000007794 180.0
WH3_k127_11466398_3 PFAM blue (type 1) copper domain protein - - - 0.0006291 42.0
WH3_k127_1147856_0 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 351.0
WH3_k127_1147856_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000002589 227.0
WH3_k127_1147856_2 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000004511 89.0
WH3_k127_11510147_0 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 303.0
WH3_k127_11510147_1 ribonuclease E activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 287.0
WH3_k127_11510147_2 Outer membrane receptor proteins, mostly Fe transport - - - 0.00000000000000000000000000000000000000000000000000000004767 202.0
WH3_k127_11510147_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000000000000009327 168.0
WH3_k127_11522429_0 Participates in both transcription termination and antitermination K02600 - - 4.027e-268 829.0
WH3_k127_11522429_1 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain K03974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 590.0
WH3_k127_11522429_2 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001754 264.0
WH3_k127_11522429_3 Phage shock protein A K03969 - - 0.00000005014 61.0
WH3_k127_11629554_0 Erythromycin esterase - - - 3.889e-204 646.0
WH3_k127_11629554_1 receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 376.0
WH3_k127_11629554_2 alpha beta - - - 0.0000002078 56.0
WH3_k127_11717880_0 peptidase M48, Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 574.0
WH3_k127_11717880_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000002325 163.0
WH3_k127_11733651_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1035.0
WH3_k127_11733651_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 7.595e-252 779.0
WH3_k127_11733651_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 479.0
WH3_k127_11733651_3 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 441.0
WH3_k127_11733651_4 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 381.0
WH3_k127_11733651_5 2'-5' RNA ligase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000003872 230.0
WH3_k127_11733651_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000000007792 149.0
WH3_k127_11748265_0 Sulfate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 585.0
WH3_k127_11748265_1 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 300.0
WH3_k127_11748265_2 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000000000000000000000000004175 233.0
WH3_k127_11748265_3 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000005194 210.0
WH3_k127_11748265_4 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000005579 149.0
WH3_k127_11842737_0 DNA polymerase K02337 - 2.7.7.7 0.0 1339.0
WH3_k127_11842737_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000116 281.0
WH3_k127_11842737_2 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000003219 75.0
WH3_k127_11842737_3 - - - - 0.000000006312 57.0
WH3_k127_11875970_0 LVIVD repeat - - - 0.0 1781.0
WH3_k127_1188083_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 6.997e-231 723.0
WH3_k127_1188083_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 318.0
WH3_k127_12026433_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 3.813e-211 670.0
WH3_k127_12026433_1 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 545.0
WH3_k127_12026433_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 516.0
WH3_k127_12026433_3 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 394.0
WH3_k127_12026433_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000363 241.0
WH3_k127_12026433_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000202 204.0
WH3_k127_12026702_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 1.135e-243 756.0
WH3_k127_12026702_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 6.245e-241 758.0
WH3_k127_12026702_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002542 273.0
WH3_k127_12026702_3 invasion associated locus B - - - 0.000000000000000000000000000000000000000000000000000000002275 206.0
WH3_k127_12026702_4 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000000000044 173.0
WH3_k127_12053791_0 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 504.0
WH3_k127_12053791_1 Outer membrane receptor proteins, mostly Fe transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 511.0
WH3_k127_12053791_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 382.0
WH3_k127_12061931_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1032.0
WH3_k127_12061931_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 512.0
WH3_k127_12061931_2 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 356.0
WH3_k127_12061931_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000007473 268.0
WH3_k127_12061931_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000001898 203.0
WH3_k127_12061931_5 - - - - 0.000000000000000000000000002003 115.0
WH3_k127_1207005_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 9.727e-301 929.0
WH3_k127_1207005_1 Histidine kinase K14980 - 2.7.13.3 1.753e-220 697.0
WH3_k127_1207005_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 429.0
WH3_k127_1207005_3 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 427.0
WH3_k127_1207005_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 379.0
WH3_k127_1207005_5 PTS fructose transporter subunit IIA K02793 - 2.7.1.191 0.000000000000000000000000000000000000000000000000000000002069 204.0
WH3_k127_1207005_6 Serine kinase of the HPr protein, regulates carbohydrate metabolism - - - 0.0000000000000000000000000000000000000000009382 163.0
WH3_k127_1207005_7 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.0000000000000000000000000000000004175 133.0
WH3_k127_1207005_8 DNA recombination protein K09760 - - 0.0000000000000000000000001974 106.0
WH3_k127_1207005_9 protein conserved in bacteria - - - 0.00000000004734 63.0
WH3_k127_12086597_0 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 4.254e-319 992.0
WH3_k127_12086597_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 508.0
WH3_k127_12086597_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005176 255.0
WH3_k127_12086597_3 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000505 235.0
WH3_k127_12092698_0 amidohydrolase - - - 1.328e-240 751.0
WH3_k127_12092698_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 521.0
WH3_k127_12092698_2 amino acid peptide transporter K03305 - - 0.00000000000000000004402 90.0
WH3_k127_12096131_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 591.0
WH3_k127_12096131_1 Transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 520.0
WH3_k127_12096131_2 Belongs to the UPF0176 family K07146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 460.0
WH3_k127_12096131_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 407.0
WH3_k127_12096131_4 chemotaxis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 366.0
WH3_k127_12096131_5 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 297.0
WH3_k127_12096131_6 Belongs to the glycosyl hydrolase 31 family K15922 - 3.2.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000007486 264.0
WH3_k127_12113761_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 8.111e-225 699.0
WH3_k127_12113761_1 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 571.0
WH3_k127_12113761_10 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002506 238.0
WH3_k127_12113761_11 Acetyltransferase (GNAT) domain K03829 - - 0.000000000000000000000000000000000000000000000000000000000003374 213.0
WH3_k127_12113761_12 DoxX K15977 - - 0.000000000000000000000000000000000000000000000001742 178.0
WH3_k127_12113761_13 - - - - 0.00000000000000000000000000000000000000000001898 167.0
WH3_k127_12113761_14 Predicted integral membrane protein (DUF2282) - - - 0.00000000000000000000000000000000000007418 147.0
WH3_k127_12113761_15 RDD family - - - 0.0000000000000000000000000000000000002285 141.0
WH3_k127_12113761_16 - - - - 0.00000000000000000000000000000000001189 141.0
WH3_k127_12113761_2 CorA-like Mg2+ transporter protein K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 461.0
WH3_k127_12113761_3 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 449.0
WH3_k127_12113761_4 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 447.0
WH3_k127_12113761_5 beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 306.0
WH3_k127_12113761_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 292.0
WH3_k127_12113761_7 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001065 279.0
WH3_k127_12113761_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000172 253.0
WH3_k127_12113761_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000434 238.0
WH3_k127_12152475_0 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 614.0
WH3_k127_12152475_1 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 600.0
WH3_k127_12152475_2 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001485 267.0
WH3_k127_12152475_3 - - - - 0.000000000000000001198 95.0
WH3_k127_12152475_4 - - - - 0.0007563 44.0
WH3_k127_12174942_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 325.0
WH3_k127_12174942_1 - - - - 0.0000000000000000000000000000000000000002987 155.0
WH3_k127_12190343_0 Toxic anion resistance - - - 3.054e-218 682.0
WH3_k127_12190343_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002901 284.0
WH3_k127_12190343_2 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000000000000000001906 168.0
WH3_k127_12190343_3 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000000000000000000007862 126.0
WH3_k127_12214957_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1229.0
WH3_k127_12214957_1 TonB dependent receptor - - - 2.66e-253 790.0
WH3_k127_12214957_2 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 572.0
WH3_k127_12214957_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 471.0
WH3_k127_12214957_4 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000003791 260.0
WH3_k127_12219271_0 Histidine kinase - - - 1.652e-292 908.0
WH3_k127_12219271_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.344e-264 822.0
WH3_k127_12219271_2 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 378.0
WH3_k127_12219271_3 Alkyl hydroperoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002687 248.0
WH3_k127_12219271_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000005892 173.0
WH3_k127_12219271_5 Pilus assembly protein K02651 - - 0.000000001549 64.0
WH3_k127_12219271_6 - - - - 0.00005465 50.0
WH3_k127_12272845_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 498.0
WH3_k127_12272845_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 299.0
WH3_k127_12272845_2 Sulfotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000122 289.0
WH3_k127_12272845_3 Protein of unknown function (DUF1294) - - - 0.000000000000000000000000000000501 124.0
WH3_k127_12272845_4 integral membrane protein K02221 - - 0.000000000000000000000000000001862 122.0
WH3_k127_12272845_5 Protein of unknown function (DUF465) K09794 - - 0.00000000000000000000002363 103.0
WH3_k127_12309552_0 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes K00639,K00652 - 2.3.1.29,2.3.1.47 8.844e-241 748.0
WH3_k127_12309552_1 phage phi-C31 gp36 major capsid-like protein - - - 9.92e-204 640.0
WH3_k127_12309552_10 Caudovirus prohead serine protease K06904 - - 0.000000000000000000000000000000000000000000000000001125 188.0
WH3_k127_12309552_11 response regulator K11443 - - 0.000000000000000000000000000000000000000000000000002785 186.0
WH3_k127_12309552_12 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000002807 188.0
WH3_k127_12309552_13 - - - - 0.0000000000000000000000000000000000000008116 157.0
WH3_k127_12309552_14 Protein of unknown function (DUF3168) - - - 0.000000000000000000000000000000000001376 143.0
WH3_k127_12309552_15 - - - - 0.0000000000000000000000000000000001121 138.0
WH3_k127_12309552_16 acyl carrier protein - - - 0.00000000000000000000000000000003656 126.0
WH3_k127_12309552_17 Protein of unknown function (DUF3572) - - - 0.0000000000000000000000000001194 117.0
WH3_k127_12309552_18 glycerophosphoryl diester phosphodiesterase - - - 0.00000000000000005082 83.0
WH3_k127_12309552_2 Terminase RNaseH-like domain - - - 5.864e-199 632.0
WH3_k127_12309552_3 portal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 610.0
WH3_k127_12309552_4 DedA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 331.0
WH3_k127_12309552_5 UMP catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 312.0
WH3_k127_12309552_6 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 306.0
WH3_k127_12309552_7 endoribonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000005428 237.0
WH3_k127_12309552_8 tail protein - - - 0.0000000000000000000000000000000000000000000000000000000000001284 213.0
WH3_k127_12309552_9 - - - - 0.000000000000000000000000000000000000000000000000000000000001029 215.0
WH3_k127_12321870_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1364.0
WH3_k127_12321870_1 Malic enzyme K00029 - 1.1.1.40 0.0 1306.0
WH3_k127_12321870_2 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 461.0
WH3_k127_12321870_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 393.0
WH3_k127_12321870_4 adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 302.0
WH3_k127_12321870_5 HNH endonuclease - - - 0.00000000000000000000000000000000000000000002589 162.0
WH3_k127_12321870_6 Hypoxia induced protein conserved region - - - 0.0000000000000000000001235 98.0
WH3_k127_12321870_7 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000002794 56.0
WH3_k127_12406095_0 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 378.0
WH3_k127_12406095_1 Bacterial PH domain K08981 - - 0.000000000000000000000000000002019 122.0
WH3_k127_12406095_2 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000000000000003096 122.0
WH3_k127_12420210_0 peptidase S9 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 607.0
WH3_k127_12423750_0 Dicarboxylate transport - - - 0.0 1071.0
WH3_k127_12423750_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 462.0
WH3_k127_12423750_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 380.0
WH3_k127_12423750_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 374.0
WH3_k127_12423750_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000008811 202.0
WH3_k127_12423750_5 protein conserved in bacteria K09978 - - 0.00000000000000000000000000000000000000000000000000001364 191.0
WH3_k127_12423750_6 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000000000000000000000000000000000000000002251 169.0
WH3_k127_12423750_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000148 131.0
WH3_k127_12423750_8 YnbE-like lipoprotein - - - 0.000000000000000002937 87.0
WH3_k127_12446900_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 524.0
WH3_k127_12446900_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 316.0
WH3_k127_12446900_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002374 275.0
WH3_k127_12446900_3 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000000003246 196.0
WH3_k127_12477360_0 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 474.0
WH3_k127_12477360_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 379.0
WH3_k127_12477360_2 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 370.0
WH3_k127_12477360_3 cytochrome C K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 262.0
WH3_k127_12477360_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002964 251.0
WH3_k127_12477360_5 - - - - 0.00000000000000000000000000000000000000000000002873 178.0
WH3_k127_12478937_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 462.0
WH3_k127_12478937_1 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 420.0
WH3_k127_12478937_2 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000001147 151.0
WH3_k127_12478937_3 - - - - 0.00000000000000000000000000000000000003215 150.0
WH3_k127_12482850_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 573.0
WH3_k127_12482850_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 524.0
WH3_k127_12482850_2 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.00000000000000000000000000000000000000000000000003165 181.0
WH3_k127_12482850_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000002294 139.0
WH3_k127_12482850_4 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000000003499 125.0
WH3_k127_12482850_5 - - - - 0.0000000000000000001091 93.0
WH3_k127_12487047_0 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 362.0
WH3_k127_12487047_1 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000553 286.0
WH3_k127_12487047_2 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000000000000000000000000000001044 179.0
WH3_k127_12487047_3 RESPONSE REGULATOR receiver - - - 0.000000000000000001922 89.0
WH3_k127_12502723_0 in Escherichia coli this protein forms a dimer and binds manganese K11532 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 548.0
WH3_k127_12502723_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 358.0
WH3_k127_12502723_2 - - - - 0.00000000000000000000000000961 114.0
WH3_k127_12502723_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000001564 65.0
WH3_k127_12532696_0 Thi4 family - - - 1.549e-238 748.0
WH3_k127_12532696_1 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 442.0
WH3_k127_12532696_2 PilZ domain - - - 0.000000000000000000000000000000000000000000108 168.0
WH3_k127_12533068_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 588.0
WH3_k127_12533068_1 type II secretion system protein K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 512.0
WH3_k127_12533068_2 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 453.0
WH3_k127_12533068_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 428.0
WH3_k127_12533068_4 pilus assembly protein TadB K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 352.0
WH3_k127_12533068_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000005403 177.0
WH3_k127_12547674_0 UDP-N-acetylmuramate-alanine ligase K01924 - 6.3.2.8 2.933e-220 691.0
WH3_k127_12547674_1 protein conserved in bacteria K09781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 407.0
WH3_k127_12547674_2 proteins, homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 372.0
WH3_k127_12547674_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 356.0
WH3_k127_12547674_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000001508 175.0
WH3_k127_12575965_0 Peptidase, M28 - - - 1.058e-262 829.0
WH3_k127_12575965_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 560.0
WH3_k127_12575965_2 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000001107 140.0
WH3_k127_12592351_0 Cupin superfamily protein K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 427.0
WH3_k127_12592351_1 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 308.0
WH3_k127_12592351_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000001197 197.0
WH3_k127_12649140_0 TonB dependent receptor K16090 - - 4.849e-251 788.0
WH3_k127_12649140_1 arsenate reductase K00537 - 1.20.4.1 0.00000009054 53.0
WH3_k127_12660942_0 Isocitrate lyase K01637 - 4.1.3.1 2.025e-307 947.0
WH3_k127_12660942_1 Transcriptional regulator K07110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 501.0
WH3_k127_12660942_2 - - - - 0.0000000000000000000432 91.0
WH3_k127_12684869_0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 548.0
WH3_k127_12684869_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 339.0
WH3_k127_12701696_0 Cytochrome c3 - - - 1.004e-200 642.0
WH3_k127_12701696_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 383.0
WH3_k127_12701696_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 377.0
WH3_k127_12701696_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 308.0
WH3_k127_12724537_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1025.0
WH3_k127_12724537_1 IV secretion system protein K03196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 572.0
WH3_k127_12724537_2 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 545.0
WH3_k127_12724537_3 type IV secretion system protein K03195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 315.0
WH3_k127_12743558_0 Belongs to the CarB family K01955 - 6.3.5.5 3.259e-295 912.0
WH3_k127_12743558_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 377.0
WH3_k127_12743558_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000115 270.0
WH3_k127_12743558_3 - - - - 0.00000000000000000000000000000000000000000000001239 180.0
WH3_k127_12743558_4 Domain of unknown function (DUF4170) - - - 0.0000000000000000000000000000001236 124.0
WH3_k127_12743558_5 - - - - 0.000000000000000000003485 97.0
WH3_k127_12743558_6 - - - - 0.000000000000000000004234 100.0
WH3_k127_12743558_7 - - - - 0.000000000000000003109 89.0
WH3_k127_12869973_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0 1005.0
WH3_k127_12869973_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 316.0
WH3_k127_12869973_2 acetolactate synthase K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 292.0
WH3_k127_12869973_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000428 105.0
WH3_k127_1288223_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002095 268.0
WH3_k127_1288223_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000001239 156.0
WH3_k127_1288223_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000005336 144.0
WH3_k127_1288223_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000003668 119.0
WH3_k127_12888754_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 3.719e-200 629.0
WH3_k127_12888754_1 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 578.0
WH3_k127_12888754_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000003154 168.0
WH3_k127_12890521_0 COG0659 Sulfate permease and related transporters (MFS superfamily) - - - 3.789e-236 737.0
WH3_k127_12890521_1 NAD(FAD)-dependent dehydrogenases K17218 - 1.8.5.4 0.000000000000000000000000001461 116.0
WH3_k127_12890521_2 transporter component K07112 - - 0.0000000000008244 69.0
WH3_k127_12895220_0 PFAM Aminotransferase class I and II K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 537.0
WH3_k127_12895220_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 429.0
WH3_k127_12895220_10 Domain of unknown function (DUF4402) - - - 0.0000000000000000000000000000000000000000000000003904 182.0
WH3_k127_12895220_11 - - - - 0.0000000000000000000000000000000004865 140.0
WH3_k127_12895220_12 Fe2 transport system protein A K04758 - - 0.00000000000000000000000001302 111.0
WH3_k127_12895220_2 Ferrous iron transport protein B K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 418.0
WH3_k127_12895220_3 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 323.0
WH3_k127_12895220_4 RpsU-divergently transcribed K18587 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 320.0
WH3_k127_12895220_5 conserved protein UCP033924 precursor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 322.0
WH3_k127_12895220_6 Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 295.0
WH3_k127_12895220_7 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002601 278.0
WH3_k127_12895220_8 Belongs to the UPF0260 family K09160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001083 267.0
WH3_k127_12895220_9 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000006471 221.0
WH3_k127_1296701_0 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1322.0
WH3_k127_12977375_0 helicase K17675 - 3.6.4.13 0.0 1165.0
WH3_k127_12977375_1 membrane - - - 2.994e-230 726.0
WH3_k127_12977375_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 570.0
WH3_k127_12977375_3 CarD family transcriptional regulator K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 328.0
WH3_k127_12977375_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 304.0
WH3_k127_12977375_5 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004651 237.0
WH3_k127_12977375_6 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007999 232.0
WH3_k127_12977375_7 - - - - 0.00000000000000000000000001631 112.0
WH3_k127_12977375_8 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.0000000000000000000000006916 108.0
WH3_k127_12990623_0 TonB dependent receptor K02014 - - 0.0 1102.0
WH3_k127_12990623_1 Major facilitator superfamily K08191 - - 0.000000000000000000000000000000000000000000007306 165.0
WH3_k127_1301729_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 572.0
WH3_k127_1301729_1 Acyl-carrier-protein s-malonyltransferase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 525.0
WH3_k127_1301729_2 Flavin-binding monooxygenase-like - - - 0.000000000000000000000000000000000000000000000000000000000000001917 220.0
WH3_k127_13019142_0 Sodium:sulfate symporter transmembrane region K14445 - - 1.973e-195 616.0
WH3_k127_13019142_1 Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine K01761 - 4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 477.0
WH3_k127_13038671_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 515.0
WH3_k127_13038671_1 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 396.0
WH3_k127_13038671_2 with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 296.0
WH3_k127_13038671_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001697 244.0
WH3_k127_13038671_4 molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000002806 241.0
WH3_k127_13039444_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 531.0
WH3_k127_13039444_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 377.0
WH3_k127_13039444_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 338.0
WH3_k127_13039444_3 - - - - 0.00000000000000000000000000000000000000009871 164.0
WH3_k127_13063336_0 Methionine synthase I (cobalamin-dependent), methyltransferase domain K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 554.0
WH3_k127_13063336_1 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 522.0
WH3_k127_1308161_0 Outer membrane protein beta-barrel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 467.0
WH3_k127_1308161_1 3-phytase K01083 - 3.1.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 464.0
WH3_k127_1308161_2 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 352.0
WH3_k127_13093912_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 515.0
WH3_k127_13093912_1 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 328.0
WH3_k127_13134757_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.312e-259 801.0
WH3_k127_13134757_1 tRNA synthetase, class II K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 497.0
WH3_k127_13134757_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000984 245.0
WH3_k127_13134757_3 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000008541 214.0
WH3_k127_13134757_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000003774 182.0
WH3_k127_13134757_5 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000006963 133.0
WH3_k127_13134757_6 - - - - 0.000004869 49.0
WH3_k127_13205645_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 402.0
WH3_k127_13205645_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 349.0
WH3_k127_13205645_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 316.0
WH3_k127_13205645_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001249 273.0
WH3_k127_13205645_4 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000146 236.0
WH3_k127_13205645_5 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000000000000000000000000000000000000001338 181.0
WH3_k127_13205645_6 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000001168 152.0
WH3_k127_13227657_0 beta-N-acetylhexosaminidase K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 511.0
WH3_k127_13227657_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007974 278.0
WH3_k127_13227657_2 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001408 252.0
WH3_k127_13227657_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000009499 67.0
WH3_k127_1323441_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 7.971e-221 688.0
WH3_k127_1323441_1 acyl-CoA dehydrogenase K00249,K00255 - 1.3.8.7,1.3.8.8 5.313e-210 657.0
WH3_k127_1323441_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 2.944e-200 631.0
WH3_k127_1323441_3 L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 568.0
WH3_k127_1323441_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 516.0
WH3_k127_1323441_5 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 415.0
WH3_k127_1323441_6 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 370.0
WH3_k127_1323441_7 Regulator K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 368.0
WH3_k127_13253673_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 1.977e-232 730.0
WH3_k127_13253673_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 533.0
WH3_k127_13253673_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 518.0
WH3_k127_13253673_3 protein conserved in bacteria K09987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 376.0
WH3_k127_13253673_4 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 309.0
WH3_k127_13253673_5 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 309.0
WH3_k127_13253673_6 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000002629 160.0
WH3_k127_1333225_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 370.0
WH3_k127_1333225_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001902 245.0
WH3_k127_13386989_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 469.0
WH3_k127_13386989_1 transporter component K07112 - - 0.0000000000000000000000000000000000000000000000000002021 187.0
WH3_k127_13386989_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000001301 147.0
WH3_k127_13386989_3 Transcriptional K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000003238 120.0
WH3_k127_13387376_0 Glycine dehydrogenase (aminomethyl-transferring) K00283 - 1.4.4.2 2.686e-276 863.0
WH3_k127_13387376_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000017 202.0
WH3_k127_13387376_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000009478 190.0
WH3_k127_13399976_0 homoserine dehydrogenase K00003 - 1.1.1.3 1.12e-199 630.0
WH3_k127_13399976_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003378 228.0
WH3_k127_13405949_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 481.0
WH3_k127_13405949_1 molecular chaperone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 451.0
WH3_k127_13405949_2 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 378.0
WH3_k127_13405949_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 306.0
WH3_k127_13405949_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000000000000000000000001756 210.0
WH3_k127_13482084_0 COG3210 Large exoproteins involved in heme utilization or adhesion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 507.0
WH3_k127_13483144_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 4.25e-322 992.0
WH3_k127_13483144_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.221e-215 679.0
WH3_k127_13483144_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 8.912e-200 632.0
WH3_k127_13483144_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 546.0
WH3_k127_13483144_4 Aldolase K01625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 317.0
WH3_k127_13554691_0 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 450.0
WH3_k127_13554691_1 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000003799 207.0
WH3_k127_13554691_2 - - - - 0.000000000000000000000000000000000000000000000004976 175.0
WH3_k127_13554691_3 PhnA protein K06193 - - 0.000000000000000000000000000000000000000000004552 169.0
WH3_k127_13554691_4 response to hydrogen peroxide - - - 0.000000000000000000000000000000000000000000007506 168.0
WH3_k127_13554691_5 Ion channel - - - 0.0000000000000000000000000000000000567 141.0
WH3_k127_13554691_6 Cold-shock protein K03704 - - 0.00000000000000000000000000005096 119.0
WH3_k127_13554691_7 - - - - 0.0000000000000003247 80.0
WH3_k127_13554691_8 - - - - 0.000000002576 62.0
WH3_k127_13554691_9 Protein of unknown function (DUF2726) - - - 0.000000009094 61.0
WH3_k127_135817_0 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 441.0
WH3_k127_136020_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 589.0
WH3_k127_136020_1 L-asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 391.0
WH3_k127_13619160_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 530.0
WH3_k127_13619160_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 439.0
WH3_k127_13619160_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 364.0
WH3_k127_13619160_3 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.00000000000000000000000000000000000000001179 155.0
WH3_k127_13619160_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000006736 106.0
WH3_k127_13657593_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 599.0
WH3_k127_13657593_1 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 448.0
WH3_k127_13657593_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 424.0
WH3_k127_13657593_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 383.0
WH3_k127_13657593_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 368.0
WH3_k127_13657593_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 332.0
WH3_k127_13657593_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 310.0
WH3_k127_13657593_7 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000003964 220.0
WH3_k127_13657593_8 - - - - 0.00000000000000000004642 93.0
WH3_k127_13657593_9 Transposase IS200 like K07491 - - 0.0004873 46.0
WH3_k127_13706845_0 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000000000000000009449 199.0
WH3_k127_13706845_1 protein conserved in bacteria - - - 0.00000000000000000000000008977 111.0
WH3_k127_13706845_2 - - - - 0.0000000000000000002121 90.0
WH3_k127_13730872_0 Acyl-CoA dehydrogenase, middle domain - - - 1.453e-221 691.0
WH3_k127_13730872_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 473.0
WH3_k127_13730872_2 COG2211 Na melibiose symporter and related transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 283.0
WH3_k127_13744035_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 599.0
WH3_k127_13744035_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 591.0
WH3_k127_13744035_2 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 452.0
WH3_k127_13744035_3 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 445.0
WH3_k127_13744035_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 395.0
WH3_k127_13744035_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000002848 197.0
WH3_k127_13744035_6 - - - - 0.0000000000000000000000000000000000001936 150.0
WH3_k127_1378825_0 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 572.0
WH3_k127_1378825_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 336.0
WH3_k127_1378825_2 - - - - 0.0000000000000000000000000000000007897 134.0
WH3_k127_1378825_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000001785 87.0
WH3_k127_1380779_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 398.0
WH3_k127_1380779_1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 332.0
WH3_k127_1380779_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000005613 201.0
WH3_k127_1380779_3 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000008208 200.0
WH3_k127_13818351_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 1.926e-202 635.0
WH3_k127_13818351_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 524.0
WH3_k127_13818351_2 Dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate K00220 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 448.0
WH3_k127_13818351_3 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 289.0
WH3_k127_13818351_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000004492 160.0
WH3_k127_1418294_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 7.696e-245 775.0
WH3_k127_1418294_1 membrane metal-binding protein K02238 - - 5.193e-207 657.0
WH3_k127_1418294_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003847 256.0
WH3_k127_1426493_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 608.0
WH3_k127_1426493_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000002666 55.0
WH3_k127_1463976_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 8.958e-274 855.0
WH3_k127_1463976_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.872e-258 805.0
WH3_k127_1463976_2 Belongs to the CarA family K01956 - 6.3.5.5 6.46e-217 677.0
WH3_k127_1463976_3 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000001649 191.0
WH3_k127_1516939_0 acyl-CoA dehydrogenase - - - 2.202e-271 838.0
WH3_k127_1516939_1 Competence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001739 258.0
WH3_k127_1516939_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001812 232.0
WH3_k127_1516939_3 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000104 162.0
WH3_k127_153493_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 6.428e-197 621.0
WH3_k127_153493_1 Major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 471.0
WH3_k127_153493_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 464.0
WH3_k127_153493_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000008683 128.0
WH3_k127_1562917_0 peptidase S9 K01278 - 3.4.14.5 0.0 1138.0
WH3_k127_1562917_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 482.0
WH3_k127_1562917_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 345.0
WH3_k127_1562917_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000000003912 218.0
WH3_k127_1580070_0 protein conserved in bacteria K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 589.0
WH3_k127_1580070_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 281.0
WH3_k127_1580070_2 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000002804 144.0
WH3_k127_1605998_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 2.063e-215 673.0
WH3_k127_1605998_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 430.0
WH3_k127_1605998_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 380.0
WH3_k127_1605998_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 345.0
WH3_k127_1612745_0 COG1505 Serine proteases of the peptidase family S9A K01322 - 3.4.21.26 0.0 1088.0
WH3_k127_1612745_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 292.0
WH3_k127_1612745_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000002154 128.0
WH3_k127_1612745_3 Phenazine biosynthesis protein PhzF - - - 0.0001226 49.0
WH3_k127_1695973_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 9.079e-220 685.0
WH3_k127_1695973_1 MASE1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 437.0
WH3_k127_1695973_2 Sulfate transporter K03321 - - 0.0000000000000000000000000000000000000000000000000000000000001774 215.0
WH3_k127_1700841_0 Histidine kinase - - - 3.28e-245 781.0
WH3_k127_1700841_1 sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 404.0
WH3_k127_1700841_2 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000009242 158.0
WH3_k127_1766160_0 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 6.937e-219 685.0
WH3_k127_1782934_0 NADH ubiquinone oxidoreductase subunit K00341 - 1.6.5.3 1.393e-288 890.0
WH3_k127_1782934_1 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 1.035e-271 845.0
WH3_k127_1782934_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000006511 84.0
WH3_k127_1790100_0 Peptidase family M28 - - - 8.216e-207 656.0
WH3_k127_1790100_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 4.17e-198 622.0
WH3_k127_1790100_10 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000002518 134.0
WH3_k127_1790100_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 501.0
WH3_k127_1790100_3 COG0695 glutaredoxin and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 386.0
WH3_k127_1790100_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 332.0
WH3_k127_1790100_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 348.0
WH3_k127_1790100_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 324.0
WH3_k127_1790100_7 PEP-CTERM motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008582 267.0
WH3_k127_1790100_8 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000671 239.0
WH3_k127_1790100_9 Adenylate kinase and related kinases - - - 0.000000000000000000000000000000000000000000000000000003349 195.0
WH3_k127_1791412_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 1.17e-227 713.0
WH3_k127_1791412_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 592.0
WH3_k127_1791412_2 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 432.0
WH3_k127_1791412_3 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 368.0
WH3_k127_1791412_4 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 359.0
WH3_k127_1791412_5 protein conserved in bacteria K09931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001679 269.0
WH3_k127_1791412_6 Fatty acid hydroxylase superfamily - - - 0.000000000000000000008414 95.0
WH3_k127_1806407_0 amidohydrolase - - - 1.671e-216 679.0
WH3_k127_1806407_1 Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 439.0
WH3_k127_180914_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1012.0
WH3_k127_180914_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 1.916e-207 652.0
WH3_k127_180914_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 295.0
WH3_k127_180914_3 AsnC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000002421 214.0
WH3_k127_180914_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000004299 207.0
WH3_k127_180914_5 Protein of unknown function (FYDLN_acid) - - - 0.000000000000000000000000000000000000000000000003174 174.0
WH3_k127_180914_6 - - - - 0.00000000000000000000000000000006825 126.0
WH3_k127_1816675_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 2.552e-208 653.0
WH3_k127_1816675_1 Inositol monophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 380.0
WH3_k127_1816675_2 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 307.0
WH3_k127_1816675_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001326 241.0
WH3_k127_1816675_4 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000005742 188.0
WH3_k127_1885678_0 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 3.997e-223 696.0
WH3_k127_1885678_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 571.0
WH3_k127_1885678_2 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 309.0
WH3_k127_1885678_3 MaoC like domain K18290 - 4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 306.0
WH3_k127_1889713_0 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01295 - 3.4.17.11 1.746e-196 618.0
WH3_k127_1889713_1 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) K01484 - 3.5.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 609.0
WH3_k127_1889713_2 arginine N-succinyltransferase K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 556.0
WH3_k127_1889713_3 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000894 266.0
WH3_k127_1931735_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 4.371e-233 725.0
WH3_k127_1931735_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 486.0
WH3_k127_1931735_2 Acetoacetyl-CoA reductase K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 417.0
WH3_k127_1931735_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 339.0
WH3_k127_1931735_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000002268 224.0
WH3_k127_1931735_5 Domain of unknown function (DUF3576) - - - 0.0000000000000000000000000000000000000000000000000000000000006542 214.0
WH3_k127_1931735_6 protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis - - - 0.000000000000000000000000000002643 121.0
WH3_k127_1931735_7 - - - - 0.000000000000000003211 87.0
WH3_k127_1931959_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.935e-321 989.0
WH3_k127_1931959_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 361.0
WH3_k127_1931959_2 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 306.0
WH3_k127_1931959_3 - - - - 0.00000000000000002174 88.0
WH3_k127_1944253_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 3.564e-244 759.0
WH3_k127_1944253_1 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 461.0
WH3_k127_1944253_2 taurine catabolism dioxygenase K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 391.0
WH3_k127_1944253_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 347.0
WH3_k127_1944253_4 YhhN family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002284 251.0
WH3_k127_1944253_5 EF hand - - - 0.0000000000000000000000000000000000000000000000000000000000000003226 224.0
WH3_k127_1944253_6 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000005602 165.0
WH3_k127_1944253_7 TadE-like protein - - - 0.000000000000000000000000000000000219 138.0
WH3_k127_1944253_8 TadE-like protein - - - 0.00000000000000000000000000007044 123.0
WH3_k127_1962940_0 receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 481.0
WH3_k127_1962940_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 385.0
WH3_k127_1962940_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 378.0
WH3_k127_1962940_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000001434 139.0
WH3_k127_1971124_0 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 3.63e-199 628.0
WH3_k127_1971124_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 488.0
WH3_k127_1971124_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000001285 215.0
WH3_k127_1971124_3 RDD family - - - 0.000000000000000000000000662 108.0
WH3_k127_1995985_0 Spermidine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 312.0
WH3_k127_1995985_1 succinylglutamate desuccinylase K06987 - - 0.00000000000000000000000000000000001133 139.0
WH3_k127_2013870_0 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 449.0
WH3_k127_2013870_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 362.0
WH3_k127_2013870_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002745 263.0
WH3_k127_2013870_3 Protein of unknown function (DUF4242) - - - 0.000000000006586 66.0
WH3_k127_2013870_4 Anti-sigma-K factor rskA - - - 0.00000000003845 66.0
WH3_k127_2074470_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 376.0
WH3_k127_2074470_1 glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 287.0
WH3_k127_2074470_2 Transcriptional K05800 - - 0.0000000000000000000000000000000000000000000000003313 181.0
WH3_k127_2074470_3 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000001139 85.0
WH3_k127_2074470_4 Asp/Glu/Hydantoin racemase K01779 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.13 0.0003276 44.0
WH3_k127_2119172_0 COG1002 Type II restriction enzyme, methylase subunits - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 555.0
WH3_k127_2119172_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 364.0
WH3_k127_2125438_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 8.08e-297 924.0
WH3_k127_2125438_1 GTP-binding protein TypA K06207 - - 1.774e-267 827.0
WH3_k127_2125970_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.014e-220 691.0
WH3_k127_2125970_1 Peptidase, M16 K07263 - - 1.084e-202 645.0
WH3_k127_2125970_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000000000000004841 225.0
WH3_k127_2125970_11 Acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000001162 184.0
WH3_k127_2125970_2 Phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 573.0
WH3_k127_2125970_3 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 434.0
WH3_k127_2125970_4 Nitroreductase family K09019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 336.0
WH3_k127_2125970_5 COG0694 Thioredoxin-like proteins and domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 327.0
WH3_k127_2125970_6 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 321.0
WH3_k127_2125970_7 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001035 253.0
WH3_k127_2125970_8 peptidase M22 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005696 251.0
WH3_k127_2125970_9 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000612 236.0
WH3_k127_2142259_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 6.102e-298 925.0
WH3_k127_2142259_1 Chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 453.0
WH3_k127_2142259_2 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 434.0
WH3_k127_2142259_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 287.0
WH3_k127_2142259_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000008334 256.0
WH3_k127_2174106_0 cytochrome C K02198 - - 4.511e-310 958.0
WH3_k127_2174106_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 509.0
WH3_k127_2174106_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 424.0
WH3_k127_2174106_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000000631 219.0
WH3_k127_2301260_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 385.0
WH3_k127_2301260_1 extracellular solute-binding protein K02035 - - 0.0000000000000000000000000000000000009655 146.0
WH3_k127_2311475_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 525.0
WH3_k127_2311475_1 DNA polymerase K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 405.0
WH3_k127_2311475_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 291.0
WH3_k127_2311475_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000001627 124.0
WH3_k127_2321487_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 578.0
WH3_k127_2321487_1 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 529.0
WH3_k127_2321487_2 YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 504.0
WH3_k127_2321487_3 In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media - - - 0.00000006864 53.0
WH3_k127_2341458_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 591.0
WH3_k127_2341458_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 453.0
WH3_k127_2341458_2 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001404 279.0
WH3_k127_2341458_3 Septum formation initiator - - - 0.00000000000000000000000000000000001848 139.0
WH3_k127_2344881_0 Lycopene cyclase protein K06443 - 5.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 499.0
WH3_k127_2344881_1 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 478.0
WH3_k127_2350264_0 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 400.0
WH3_k127_2350264_1 MltA-interacting protein MipA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 302.0
WH3_k127_2391061_0 receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 582.0
WH3_k127_2391061_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 375.0
WH3_k127_2402448_0 Peptidase, M28 - - - 4.178e-198 627.0
WH3_k127_2402448_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 427.0
WH3_k127_2402448_2 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000000001169 124.0
WH3_k127_2402448_3 Copper-binding protein - - - 0.00000000000000000000000009597 111.0
WH3_k127_2416061_0 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 440.0
WH3_k127_2416061_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 419.0
WH3_k127_2416061_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 313.0
WH3_k127_2431011_0 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 336.0
WH3_k127_2431011_1 SapC - - - 0.000000002 64.0
WH3_k127_2505163_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 586.0
WH3_k127_2505163_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 286.0
WH3_k127_2505163_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000004098 179.0
WH3_k127_2506387_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 602.0
WH3_k127_2506387_1 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 447.0
WH3_k127_2506387_2 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 362.0
WH3_k127_2506387_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 317.0
WH3_k127_2506387_4 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000001385 248.0
WH3_k127_2506387_5 oligoketide cyclase lipid transport protein K18588 - - 0.00000000000000000000000000000000000000002826 157.0
WH3_k127_2506387_6 nitrogen regulatory protein PII - - - 0.0000000000000000000000000000000000000008378 151.0
WH3_k127_2506387_7 - - - - 0.00000000000000003007 83.0
WH3_k127_2515983_0 glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1926.0
WH3_k127_2515983_1 cytochrome P450 - - - 1.806e-207 653.0
WH3_k127_2515983_10 Transcriptional regulator K07729 - - 0.00000000000000000000000003667 108.0
WH3_k127_2515983_2 pyridine nucleotide-disulfide oxidoreductase K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 591.0
WH3_k127_2515983_3 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 521.0
WH3_k127_2515983_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 517.0
WH3_k127_2515983_5 ABC-type Na efflux pump, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 470.0
WH3_k127_2515983_6 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 340.0
WH3_k127_2515983_7 conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000005562 257.0
WH3_k127_2515983_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000001336 203.0
WH3_k127_2515983_9 - - - - 0.000000000000000000000000000000000000000000000002214 180.0
WH3_k127_2528572_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 3201.0
WH3_k127_2528572_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1067.0
WH3_k127_2528572_2 Belongs to the carbohydrate kinase PfkB family K16370 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 365.0
WH3_k127_2528572_3 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000003793 164.0
WH3_k127_2558258_0 signal peptide peptidase K04773 - - 3.898e-297 921.0
WH3_k127_2558258_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 560.0
WH3_k127_2558258_2 dihydroorotase K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 512.0
WH3_k127_2558258_3 Domain of unknown function (DUF4189) - - - 0.00000000000000000000000000002398 133.0
WH3_k127_2558258_4 - - - - 0.000000000832 68.0
WH3_k127_2559331_0 Peptidase S41 K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 450.0
WH3_k127_2559331_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 367.0
WH3_k127_2559331_2 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.000000000000518 72.0
WH3_k127_2576987_0 - - - - 0.00000000000000000000001092 111.0
WH3_k127_2576987_1 Polysaccharide deacetylase - - - 0.000000002043 62.0
WH3_k127_2591041_0 Phage shock protein A K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 383.0
WH3_k127_2591041_1 SufE protein probably involved in Fe-S center assembly K02426 - - 0.0000000000000000000000000000000000000000000000000000000000000000001408 231.0
WH3_k127_2591041_2 PspC domain K03973 - - 0.00000000000000000000000000000000000000000000000000000001937 199.0
WH3_k127_2591041_3 - - - - 0.00000000000000000000000000000000000000001197 157.0
WH3_k127_2591041_4 Phage shock protein B K03970 - - 0.00000000000000000000000000000000000003577 144.0
WH3_k127_2591041_5 protein conserved in bacteria K09790 - - 0.00000000000000000000000000001532 119.0
WH3_k127_2591041_6 - - - - 0.000000000000000000000000000131 117.0
WH3_k127_2591041_7 - - - - 0.0000000000000000009461 89.0
WH3_k127_2591041_8 - - - - 0.00000003929 59.0
WH3_k127_259612_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 6.221e-217 692.0
WH3_k127_259612_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 2.346e-194 611.0
WH3_k127_259612_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 467.0
WH3_k127_259612_3 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 406.0
WH3_k127_259612_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 390.0
WH3_k127_259612_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 359.0
WH3_k127_259612_6 Protein of unknown function (DUF4230) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 280.0
WH3_k127_259612_7 Protein of unknown function (DUF1465) K13592 - - 0.00000000000000000000000000000000000000000000004387 174.0
WH3_k127_259612_8 Protein of unknown function (DUF465) - - - 0.000000000000000000000000428 105.0
WH3_k127_259612_9 Protein of unknown function (DUF465) - - - 0.0000000000003049 72.0
WH3_k127_2617541_0 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 488.0
WH3_k127_2617541_1 Aminomethyltransferase K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 354.0
WH3_k127_2617541_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 292.0
WH3_k127_2617541_3 EamA-like transporter family K15268 - - 0.00000000000000000000000000000000000000000000184 172.0
WH3_k127_2617541_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000002409 68.0
WH3_k127_2619593_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 9.339e-274 848.0
WH3_k127_2619593_1 Major Facilitator - - - 3.691e-261 817.0
WH3_k127_2619593_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 445.0
WH3_k127_2619593_3 synthesis repressor PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002517 246.0
WH3_k127_2619593_4 NifU homolog involved in Fe-S cluster formation - - - 0.000000000001872 67.0
WH3_k127_2619593_5 Peptidase, M28 - - - 0.000000000002197 68.0
WH3_k127_2680004_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1075.0
WH3_k127_268232_0 Ring hydroxylating alpha subunit (catalytic domain) - - - 3.202e-195 616.0
WH3_k127_268232_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 385.0
WH3_k127_268232_2 Major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 319.0
WH3_k127_268232_3 Methyltransferase K08316 - 2.1.1.171 0.0000000000000959 74.0
WH3_k127_2766899_0 chemotaxis protein K03407 - 2.7.13.3 1.167e-227 730.0
WH3_k127_2766899_1 Aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 406.0
WH3_k127_2766899_2 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 298.0
WH3_k127_2766899_3 chemotaxis K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000009162 220.0
WH3_k127_2766899_4 TonB dependent receptor K16090 - - 0.00000000000000000000000000000000000000000000000000005571 188.0
WH3_k127_2766899_5 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000171 172.0
WH3_k127_2766899_6 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000344 93.0
WH3_k127_2783720_0 Alkyl hydroperoxide reductase K03387 - - 4.139e-257 802.0
WH3_k127_2783720_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 4.113e-218 690.0
WH3_k127_2783720_2 membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 574.0
WH3_k127_2783720_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 393.0
WH3_k127_2783720_4 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 323.0
WH3_k127_2783720_5 import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 302.0
WH3_k127_2783720_6 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009372 268.0
WH3_k127_2783720_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000001838 209.0
WH3_k127_2797351_0 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 394.0
WH3_k127_2797351_1 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000003889 204.0
WH3_k127_2797351_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000001033 74.0
WH3_k127_2805294_0 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) K09883 - 6.6.1.2 1.162e-243 762.0
WH3_k127_2805294_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 386.0
WH3_k127_2825136_0 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 469.0
WH3_k127_2825136_1 - - - - 0.00000000000000000000001021 101.0
WH3_k127_2840626_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 554.0
WH3_k127_2840626_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 428.0
WH3_k127_2840626_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 316.0
WH3_k127_2840626_3 metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000009996 171.0
WH3_k127_296676_0 antiporter - - - 2.119e-274 850.0
WH3_k127_296676_1 Cytochrome c1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 395.0
WH3_k127_296676_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005727 268.0
WH3_k127_296676_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000001581 157.0
WH3_k127_2975110_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.395e-245 766.0
WH3_k127_2975110_1 Phospholipase D Active site motif K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 482.0
WH3_k127_2975110_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000002585 206.0
WH3_k127_2975110_3 Chromosome partitioning - - - 0.00000000000000000000000000000000000000000000001015 173.0
WH3_k127_2975110_4 Belongs to the UPF0262 family - - - 0.0000000000000000000000000000000000000000000024 168.0
WH3_k127_307322_0 usher protein - - - 0.0 1045.0
WH3_k127_307322_1 COG3121 P pilus assembly protein, chaperone PapD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 363.0
WH3_k127_307322_2 Domain of unknown function (DUF4402) - - - 0.0000000000000000000000000000000005617 138.0
WH3_k127_3111967_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0 1054.0
WH3_k127_3111967_1 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 470.0
WH3_k127_3111967_2 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 304.0
WH3_k127_3119624_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 384.0
WH3_k127_3119624_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 327.0
WH3_k127_3119624_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000002212 233.0
WH3_k127_3132630_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 572.0
WH3_k127_3132630_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 410.0
WH3_k127_3152194_0 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 1.543e-250 775.0
WH3_k127_3152194_1 FAD linked - - - 2.652e-218 687.0
WH3_k127_3152194_10 acyl-CoA dehydrogenase - - - 0.0001605 53.0
WH3_k127_3152194_2 Belongs to the DEAD box helicase family - - - 4.197e-204 645.0
WH3_k127_3152194_3 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 510.0
WH3_k127_3152194_4 (3S)-citramalyl-CoA lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 469.0
WH3_k127_3152194_5 SapC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 391.0
WH3_k127_3152194_6 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 360.0
WH3_k127_3152194_7 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 342.0
WH3_k127_3152194_8 cheY-homologous receiver domain K13589 - - 0.0000000000000000000000000000000000000000000000000000000000009996 211.0
WH3_k127_3152194_9 - - - - 0.0000000000000000000000000000000000000000000001618 173.0
WH3_k127_3188520_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1113.0
WH3_k127_3188520_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000001833 179.0
WH3_k127_3189632_0 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00528 - 1.18.1.2,1.19.1.1 3.907e-220 689.0
WH3_k127_3189632_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 592.0
WH3_k127_3189632_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K22250 - 3.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 446.0
WH3_k127_3189632_3 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 286.0
WH3_k127_3242828_0 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 445.0
WH3_k127_3242828_1 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 385.0
WH3_k127_3242828_2 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 372.0
WH3_k127_3242828_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002058 268.0
WH3_k127_3270714_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 545.0
WH3_k127_3270714_1 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 329.0
WH3_k127_3297429_0 RNA polymerase sigma K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 526.0
WH3_k127_3297429_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 465.0
WH3_k127_3297429_2 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000000000000000000000000000005135 161.0
WH3_k127_3297429_3 Histidine phosphotransferase C-terminal domain K13588 - - 0.00000000000000000000000000000000000003345 148.0
WH3_k127_3297429_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000009154 124.0
WH3_k127_3313586_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1590.0
WH3_k127_3313586_1 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 534.0
WH3_k127_3313586_2 RND efflux system, outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 535.0
WH3_k127_3313586_3 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 400.0
WH3_k127_3313586_4 ABC transporter, ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 371.0
WH3_k127_3313586_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 329.0
WH3_k127_3313586_6 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001269 278.0
WH3_k127_3313586_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002012 235.0
WH3_k127_3313586_8 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000004869 108.0
WH3_k127_3358468_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 436.0
WH3_k127_3358468_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 288.0
WH3_k127_336326_0 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 4.764e-260 807.0
WH3_k127_336326_1 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 484.0
WH3_k127_3411891_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 1.076e-284 888.0
WH3_k127_3411891_1 Aminotransferase K14261 - - 4.242e-236 733.0
WH3_k127_3411891_10 - - - - 0.0000000000000000000000000002222 120.0
WH3_k127_3411891_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 413.0
WH3_k127_3411891_3 YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 378.0
WH3_k127_3411891_4 Phasin protein - - - 0.00000000000000000000000000000000000000000000000000004867 197.0
WH3_k127_3411891_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000000515 183.0
WH3_k127_3411891_6 response regulator - - - 0.000000000000000000000000000000000000001226 156.0
WH3_k127_3411891_7 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000003034 151.0
WH3_k127_3411891_9 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000001727 136.0
WH3_k127_3466181_0 Protein of unknown function (DUF3376) - - - 4.143e-256 802.0
WH3_k127_3466181_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.546e-246 766.0
WH3_k127_3466181_2 Colicin V production protein K03558 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005065 249.0
WH3_k127_3466181_3 NifU homolog involved in Fe-S cluster formation - - - 0.00000000000000000000001985 103.0
WH3_k127_3531989_0 Major facilitator superfamily - - - 2.683e-209 657.0
WH3_k127_3531989_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000749 203.0
WH3_k127_3541481_0 helicase K03724 - - 0.0 1361.0
WH3_k127_3541481_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.0 1056.0
WH3_k127_3541481_10 - - - - 0.000005702 51.0
WH3_k127_3541481_2 phosphomannomutase K01840 - 5.4.2.8 6.576e-257 796.0
WH3_k127_3541481_3 sulfate adenylyltransferase K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 543.0
WH3_k127_3541481_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 396.0
WH3_k127_3541481_5 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 390.0
WH3_k127_3541481_6 antiporter - - - 0.00000000000000000000000000000000000001476 146.0
WH3_k127_3541481_7 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins K03286 - - 0.000000000000000000000000000000000007816 147.0
WH3_k127_3541481_8 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000001554 120.0
WH3_k127_3541481_9 Biopolymer transport protein K03559 - - 0.000000000000000001711 85.0
WH3_k127_3616965_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.208e-275 851.0
WH3_k127_3616965_1 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 425.0
WH3_k127_3616965_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000007954 251.0
WH3_k127_3616965_3 - - - - 0.00000000000000000000000000000000000000000000000009813 180.0
WH3_k127_3616965_4 protein conserved in bacteria K09948 - - 0.000000000000000000000000000000000000000000000006794 174.0
WH3_k127_3616965_5 Belongs to the UPF0335 family - - - 0.00000000000000000000000000000000000003322 143.0
WH3_k127_3616965_6 - - - - 0.000004217 51.0
WH3_k127_3624621_0 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 549.0
WH3_k127_3624621_1 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 427.0
WH3_k127_3624621_2 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 369.0
WH3_k127_3638590_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 530.0
WH3_k127_3638590_1 Transport of potassium into the cell K03549 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 406.0
WH3_k127_3638590_2 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 296.0
WH3_k127_3638590_3 2-methylthioadenine K18707 - 2.8.4.5 0.00000000000000000000000000000000000000008638 153.0
WH3_k127_3692363_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.946e-245 763.0
WH3_k127_3692363_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 315.0
WH3_k127_3692363_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000001118 243.0
WH3_k127_3692363_3 Belongs to the Fur family K09823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000333 241.0
WH3_k127_369797_0 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 431.0
WH3_k127_369797_1 to the N-terminal domain of Lon protease K07157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 323.0
WH3_k127_369797_2 UPF0056 membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 297.0
WH3_k127_369797_3 ketosteroid isomerase - - - 0.000000000000000000000000000000000000000000000000000000000001931 214.0
WH3_k127_369797_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000131 198.0
WH3_k127_369797_5 Domain of unknown function (DUF1330) - - - 0.0000000000000001575 83.0
WH3_k127_369797_6 Carboxymuconolactone decarboxylase family - - - 0.0000000005452 62.0
WH3_k127_3804921_0 metallo-beta-lactamase K12574 - - 1.399e-240 749.0
WH3_k127_3804921_1 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001995 259.0
WH3_k127_3804921_2 Protein of unknown function (DUF1467) - - - 0.00000000000000000000000000000003624 127.0
WH3_k127_3820356_0 aminopeptidase N K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 562.0
WH3_k127_3820356_1 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 391.0
WH3_k127_3820356_2 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 363.0
WH3_k127_3820356_3 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000003006 111.0
WH3_k127_3849936_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 995.0
WH3_k127_3866464_0 argininosuccinate lyase K01755 - 4.3.2.1 9.247e-250 775.0
WH3_k127_3866464_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.915e-211 662.0
WH3_k127_3866464_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 410.0
WH3_k127_3866464_3 Siroheme synthase K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 337.0
WH3_k127_3866464_4 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000000000003518 196.0
WH3_k127_3866464_5 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000001026 109.0
WH3_k127_3866464_6 - - - - 0.0000000000000000000000005039 108.0
WH3_k127_3869505_0 Methanol dehydrogenase K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 334.0
WH3_k127_3869505_1 membrane K08988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
WH3_k127_3869505_2 Nudix hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000139 258.0
WH3_k127_3869505_3 KR domain - - - 0.0000000000000000000000000000000009289 137.0
WH3_k127_3880836_0 type IV secretion system K03199 - - 0.0 1032.0
WH3_k127_3919011_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.0 1063.0
WH3_k127_3919011_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000005552 151.0
WH3_k127_3985692_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 2.718e-207 653.0
WH3_k127_3985692_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 366.0
WH3_k127_3985692_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000007143 213.0
WH3_k127_3985692_3 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000001429 83.0
WH3_k127_3985692_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00005644 45.0
WH3_k127_4027147_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 2.037e-284 882.0
WH3_k127_4027147_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 610.0
WH3_k127_4027147_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 496.0
WH3_k127_4027147_3 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 312.0
WH3_k127_4027147_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000000000000000000000000000000000000000000000000000001003 198.0
WH3_k127_4027147_5 DDE domain - - - 0.00000000000000000000000000000000000000000000000000000001671 198.0
WH3_k127_4038683_0 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 529.0
WH3_k127_4038683_1 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006413 278.0
WH3_k127_4038683_2 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000000004674 216.0
WH3_k127_4038683_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000001262 190.0
WH3_k127_4038683_4 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000000000000000001526 173.0
WH3_k127_4038683_5 - - - - 0.000000000000008051 76.0
WH3_k127_4094526_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 585.0
WH3_k127_4094526_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 331.0
WH3_k127_4094526_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000005812 208.0
WH3_k127_4099771_0 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 423.0
WH3_k127_4099771_1 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 355.0
WH3_k127_4099771_2 NADPH-dependent FMN reductase K00299 - 1.5.1.38 0.00000000000000000000000000000000000000000000000000000000000007495 217.0
WH3_k127_4099771_3 3,4-dihydroxy-2-butanone 4-phosphate synthase - - - 0.0000000000000000000000000000000000000000000000000000003746 205.0
WH3_k127_4099771_4 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000002084 67.0
WH3_k127_4164130_0 lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 447.0
WH3_k127_4164130_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 341.0
WH3_k127_4180141_0 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 531.0
WH3_k127_4180141_1 sterol desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 392.0
WH3_k127_4180141_2 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007265 282.0
WH3_k127_4180141_3 DNA repair protein MmcB-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001199 251.0
WH3_k127_4180141_4 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.000000000000000000000000000000000000001576 158.0
WH3_k127_4180141_5 COG3316 Transposase and inactivated derivatives - - - 0.00000000000000000005532 89.0
WH3_k127_4186620_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1132.0
WH3_k127_4186620_1 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 3.352e-216 698.0
WH3_k127_4186620_2 - - - - 0.00000000000000000000000000000000000000000006348 170.0
WH3_k127_4239539_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 488.0
WH3_k127_4239539_1 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 486.0
WH3_k127_4239539_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 480.0
WH3_k127_4239539_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 357.0
WH3_k127_4239539_4 molecular chaperone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 300.0
WH3_k127_4239539_5 Aerobic cobaltochelatase subunit CobS K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000003673 233.0
WH3_k127_4239539_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000002807 188.0
WH3_k127_4239539_7 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000000000000003704 135.0
WH3_k127_4239539_8 KR domain - - - 0.00000000000003009 77.0
WH3_k127_4241209_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 514.0
WH3_k127_4241209_1 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 388.0
WH3_k127_4247220_0 Histidine kinase K13587 - 2.7.13.3 0.0 1068.0
WH3_k127_4247220_1 - - - - 1.315e-219 691.0
WH3_k127_4247220_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 507.0
WH3_k127_4247220_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 281.0
WH3_k127_4247220_4 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 260.0
WH3_k127_4247220_5 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.000000000000000000000000000000196 134.0
WH3_k127_4256620_0 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 597.0
WH3_k127_4256620_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004143 265.0
WH3_k127_4256620_2 Aminoglycoside phosphotransferase - - - 0.000000004847 57.0
WH3_k127_4365277_0 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 587.0
WH3_k127_4365277_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 433.0
WH3_k127_4365277_2 - - - - 0.000000000000000000000000000000000000002862 151.0
WH3_k127_4365277_3 FAD binding domain - - - 0.000000000000004932 78.0
WH3_k127_4414277_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 584.0
WH3_k127_4414277_1 thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007172 246.0
WH3_k127_4414277_2 hydroxylase K15746 - 1.14.15.24 0.000000000000000000000000000000000000000000000000000000000000000295 224.0
WH3_k127_4418897_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 299.0
WH3_k127_4418897_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000009237 127.0
WH3_k127_4418897_2 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000002526 115.0
WH3_k127_4468907_0 beta-galactosidase K12308 - 3.2.1.23 1.978e-281 879.0
WH3_k127_4468907_1 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 466.0
WH3_k127_4468907_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000002973 153.0
WH3_k127_4468907_3 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000003275 124.0
WH3_k127_449144_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 7.157e-203 636.0
WH3_k127_4504510_0 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 417.0
WH3_k127_4504510_1 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001944 283.0
WH3_k127_4504510_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000002464 123.0
WH3_k127_4512733_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 7.064e-216 676.0
WH3_k127_4512733_1 Protein of unknown function (DUF2892) - - - 0.00000000000000000000001628 100.0
WH3_k127_4512733_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000003439 80.0
WH3_k127_4545715_0 Sodium:sulfate symporter transmembrane region K14445 - - 0.000000000000000000000000000000000000000000000000000000000000001245 221.0
WH3_k127_4545715_1 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000002873 173.0
WH3_k127_4545715_2 TonB-dependent receptor K02014 - - 0.0000000000000000000006318 100.0
WH3_k127_4548032_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1352.0
WH3_k127_4548032_1 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000754 272.0
WH3_k127_4548032_2 Competence protein - - - 0.0000000000000000000000000000000000000000000000000005663 188.0
WH3_k127_4548032_3 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000005872 163.0
WH3_k127_4548032_4 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000003074 96.0
WH3_k127_4630204_0 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 1.517e-216 676.0
WH3_k127_4630204_1 5-aminolevulinic acid synthase K00643 - 2.3.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 499.0
WH3_k127_4672960_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 522.0
WH3_k127_4672960_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001649 235.0
WH3_k127_4686446_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1031.0
WH3_k127_4686446_1 Peptidase, M28 - - - 1.468e-212 667.0
WH3_k127_4721611_0 Transport of potassium into the cell K03549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 326.0
WH3_k127_4721611_1 Alkyl hydroperoxide reductase K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001093 258.0
WH3_k127_4721611_2 cytochrome C K02198 - - 0.0000000000000000000000000000000000000000000000000000000000004461 213.0
WH3_k127_4721611_3 Transport of potassium into the cell K03549 - - 0.000000000000000000000000000000000000000000000000000000000007138 211.0
WH3_k127_4721611_4 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000000000000003137 196.0
WH3_k127_4721611_5 Cytochrome c biogenesis factor K02200 - - 0.0000000000000000000000000000000000000000000000000002325 193.0
WH3_k127_474617_0 COG2211 Na melibiose symporter and related transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 496.0
WH3_k127_474617_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 283.0
WH3_k127_4806797_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.009e-222 693.0
WH3_k127_4806797_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 574.0
WH3_k127_4806797_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 520.0
WH3_k127_4806797_3 LppC putative lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 512.0
WH3_k127_4806797_4 Belongs to the 'phage' integrase family K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 434.0
WH3_k127_4806797_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 410.0
WH3_k127_4806797_6 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000000000000000002741 172.0
WH3_k127_4806797_7 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.000006696 52.0
WH3_k127_4843185_0 overlaps another CDS with the same product name K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 503.0
WH3_k127_4843185_1 overlaps another CDS with the same product name K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 457.0
WH3_k127_4843185_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 391.0
WH3_k127_4843185_3 Ferredoxin K04755 - - 0.00000000000000000000000000000000000000000002378 164.0
WH3_k127_4859843_0 Protein of unknown function (DUF1343) - - - 1.13e-227 712.0
WH3_k127_4859843_1 Von Willebrand factor A K09989 - - 1.851e-224 696.0
WH3_k127_4859843_2 - - - - 0.0000000000000000000000000003713 116.0
WH3_k127_4859843_3 - - - - 0.000000000000000002814 85.0
WH3_k127_492156_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 590.0
WH3_k127_492156_1 Glycine cleavage system T protein K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 518.0
WH3_k127_492156_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000006848 213.0
WH3_k127_5006618_0 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 482.0
WH3_k127_5006618_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000001457 199.0
WH3_k127_5006618_2 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.000000000000000000000000000000000000000000000000001313 184.0
WH3_k127_5006618_3 - - - - 0.00000000000001449 79.0
WH3_k127_5007513_0 Protein of unknown function (DUF3089) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 543.0
WH3_k127_5007513_1 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 452.0
WH3_k127_5007513_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 438.0
WH3_k127_5007513_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 422.0
WH3_k127_5007513_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 404.0
WH3_k127_5007513_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 286.0
WH3_k127_5007513_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006034 246.0
WH3_k127_5007513_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000000000000000003768 224.0
WH3_k127_5007513_8 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000008491 191.0
WH3_k127_5007513_9 pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000959 150.0
WH3_k127_5036529_0 nitrogen fixation sensor protein fixL K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 464.0
WH3_k127_5036529_1 part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes K14987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001404 264.0
WH3_k127_5036529_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000008509 221.0
WH3_k127_5036529_3 - - - - 0.00000000000000000000000000000006946 139.0
WH3_k127_5036529_4 Fatty acid desaturase K00496 - 1.14.15.3 0.00000000621 56.0
WH3_k127_5078311_0 peptidase S9 K01354 - 3.4.21.83 0.0 1159.0
WH3_k127_5078311_1 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.0 1080.0
WH3_k127_5078311_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 343.0
WH3_k127_5078311_3 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000082 220.0
WH3_k127_5078311_4 thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000000000000007426 210.0
WH3_k127_5111842_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.255e-294 910.0
WH3_k127_5111842_1 Protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 510.0
WH3_k127_5111842_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007931 248.0
WH3_k127_5111842_3 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K13642 - - 0.00000000000000000000000000000000000000000000000000000001659 201.0
WH3_k127_5126385_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 503.0
WH3_k127_5126385_1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 386.0
WH3_k127_5126385_2 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000316 269.0
WH3_k127_5126385_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000000000000004679 223.0
WH3_k127_5126385_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000000001081 124.0
WH3_k127_5126385_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000122 100.0
WH3_k127_5129224_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1202.0
WH3_k127_5158516_0 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 365.0
WH3_k127_5158516_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 334.0
WH3_k127_5158516_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 313.0
WH3_k127_5158516_3 protein conserved in bacteria K09985 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003527 282.0
WH3_k127_5158516_4 - - - - 0.000000000000000000000007084 107.0
WH3_k127_5234286_0 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 0.0 1116.0
WH3_k127_5234286_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 8.741e-267 828.0
WH3_k127_5234286_10 metalloprotease K07054 - - 0.00000000009533 64.0
WH3_k127_5234286_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 526.0
WH3_k127_5234286_3 PFAM Alpha beta hydrolase fold-3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 430.0
WH3_k127_5234286_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 418.0
WH3_k127_5234286_5 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 430.0
WH3_k127_5234286_6 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 287.0
WH3_k127_5234286_7 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003218 260.0
WH3_k127_5234286_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000001157 235.0
WH3_k127_5234286_9 Antirepressor regulating drug resistance - - - 0.0000000000000000000000000000000000000001337 160.0
WH3_k127_5243466_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0 1011.0
WH3_k127_5243466_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000006459 190.0
WH3_k127_5248204_0 enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 513.0
WH3_k127_5248204_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 455.0
WH3_k127_5248204_2 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 434.0
WH3_k127_5248204_3 cytochrome c biogenesis K02200 - - 0.000000000000000000000000000000000000000000000000000006022 194.0
WH3_k127_5267650_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 443.0
WH3_k127_5267650_1 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 434.0
WH3_k127_5278182_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 6.14e-249 775.0
WH3_k127_5278182_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000995 194.0
WH3_k127_531371_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000523 618.0
WH3_k127_531371_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 439.0
WH3_k127_531371_2 2-methylthioadenine K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 426.0
WH3_k127_531371_3 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000006898 202.0
WH3_k127_5322611_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 3.764e-198 621.0
WH3_k127_5322611_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 580.0
WH3_k127_5322611_2 Methyltransferase small domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 292.0
WH3_k127_5332583_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 8.288e-209 654.0
WH3_k127_5332583_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 561.0
WH3_k127_5332583_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 527.0
WH3_k127_5332583_3 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000004367 191.0
WH3_k127_5332583_4 acyl-CoA dehydrogenase - - - 0.0000006066 51.0
WH3_k127_5357946_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.648e-288 893.0
WH3_k127_5357946_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.185e-280 871.0
WH3_k127_5382237_0 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 373.0
WH3_k127_5382237_1 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000000000000001302 169.0
WH3_k127_5412183_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 1.388e-205 653.0
WH3_k127_5412183_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 399.0
WH3_k127_5412183_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 341.0
WH3_k127_5412183_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 341.0
WH3_k127_5412183_4 Domain of unknown function (DUF4167) - - - 0.000000000000000000000000000000000001114 149.0
WH3_k127_541894_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1302.0
WH3_k127_541894_1 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004789 254.0
WH3_k127_5513801_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0 1166.0
WH3_k127_5513801_1 Glutathione S-transferase K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 458.0
WH3_k127_5513801_2 - - - - 0.000000000000000000000000000000000000000000000000000000002408 205.0
WH3_k127_5513801_3 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000001409 185.0
WH3_k127_5513801_4 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000001154 182.0
WH3_k127_5513801_5 - - - - 0.000000000000000000000000000000000000000000000002337 181.0
WH3_k127_5513801_6 periplasmic protein - - - 0.000000000145 64.0
WH3_k127_5514843_0 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 382.0
WH3_k127_5514843_1 COG3773 Cell wall hydrolyses involved in spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003265 260.0
WH3_k127_5514843_2 Protein of unknown function (DUF1491) - - - 0.00000000000000000000000000000000001375 138.0
WH3_k127_5531415_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1071.0
WH3_k127_5531415_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000002256 226.0
WH3_k127_5531415_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000008951 130.0
WH3_k127_5537091_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.967e-206 645.0
WH3_k127_5537091_1 - - - - 0.000000000000000000000000000000000000000000000001613 177.0
WH3_k127_5537091_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000007826 117.0
WH3_k127_5559564_0 Hemolysin K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 405.0
WH3_k127_5559564_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 283.0
WH3_k127_5559564_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001989 282.0
WH3_k127_5559564_3 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.000000000000000000000000000000000000000000000000000000000000000000008528 237.0
WH3_k127_5559564_4 Membrane fusogenic activity K09806 - - 0.0000000000000000000000000000000002574 134.0
WH3_k127_5559564_5 - - - - 0.0000004251 58.0
WH3_k127_5615792_0 e3 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 302.0
WH3_k127_5615792_1 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001047 279.0
WH3_k127_5615792_2 Phosphopantetheine attachment site - - - 0.00000000000007092 79.0
WH3_k127_5635110_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1165.0
WH3_k127_5635110_1 amino acid peptide transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 394.0
WH3_k127_5635110_2 Cupin domain - - - 0.0001398 49.0
WH3_k127_5647206_0 COG0463 Glycosyltransferases involved in cell wall biogenesis K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 509.0
WH3_k127_5647206_1 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000003162 266.0
WH3_k127_5647206_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000002017 106.0
WH3_k127_5688175_0 TonB dependent receptor - - - 0.0 1159.0
WH3_k127_5688175_1 Ammonium Transporter K03320 - - 9.998e-212 666.0
WH3_k127_5688175_2 COG1253 Hemolysins and related proteins containing CBS domains K03699 - - 9.154e-202 636.0
WH3_k127_5688175_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 463.0
WH3_k127_5688175_4 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 393.0
WH3_k127_5688175_5 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 331.0
WH3_k127_5688175_6 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000007482 199.0
WH3_k127_5688175_7 endonuclease - - - 0.000000000000000000001111 95.0
WH3_k127_5694977_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 415.0
WH3_k127_5694977_1 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 353.0
WH3_k127_5694977_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000005958 234.0
WH3_k127_5732554_0 Belongs to the peptidase M16 family K07263 - - 0.0 1050.0
WH3_k127_5732554_1 receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 536.0
WH3_k127_5732554_2 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 285.0
WH3_k127_5755735_0 Leukotriene A4 hydrolase, C-terminal - - - 7.582e-218 689.0
WH3_k127_5755735_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000001983 153.0
WH3_k127_5757944_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 439.0
WH3_k127_5757944_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000218 280.0
WH3_k127_5757944_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000006338 139.0
WH3_k127_580912_0 Helicase K03722 - 3.6.4.12 0.0 1467.0
WH3_k127_580912_1 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 289.0
WH3_k127_580912_2 transcriptional K13639 - - 0.00000000000000000000000000000000000000000000000000000000000000003531 226.0
WH3_k127_580912_3 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000000000000000000000000000000000005773 229.0
WH3_k127_580912_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000001609 174.0
WH3_k127_580912_5 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000009941 161.0
WH3_k127_580912_6 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000001091 100.0
WH3_k127_580912_7 - - - - 0.00000000000000000000008093 104.0
WH3_k127_582917_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 380.0
WH3_k127_582917_1 Isochorismatase family K13995 - 3.5.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
WH3_k127_5854932_0 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 1.688e-280 866.0
WH3_k127_5854932_1 Belongs to the peptidase M17 family K01255 - 3.4.11.1 3.89e-214 691.0
WH3_k127_5854932_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 489.0
WH3_k127_5854932_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 440.0
WH3_k127_5854932_4 protein conserved in bacteria K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 370.0
WH3_k127_5854932_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 302.0
WH3_k127_5854932_6 lysozyme K01185 - 3.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000002783 244.0
WH3_k127_5854932_7 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000000004211 205.0
WH3_k127_5854932_8 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000001021 171.0
WH3_k127_5854932_9 NLP P60 protein - - - 0.000000000000000000000000000000003708 131.0
WH3_k127_5864062_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 1.801e-195 614.0
WH3_k127_5864062_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 467.0
WH3_k127_5864062_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000007884 68.0
WH3_k127_5886437_0 Carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 496.0
WH3_k127_5886437_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 323.0
WH3_k127_5886437_2 protein involved in cysteine biosynthesis K06203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002256 256.0
WH3_k127_5886437_3 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000000009257 204.0
WH3_k127_5886437_4 - - - - 0.000000000000000000000000000000000000001634 151.0
WH3_k127_5886437_5 FeS assembly SUF system protein - - - 0.000000000000002591 75.0
WH3_k127_592912_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 586.0
WH3_k127_592912_1 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002923 286.0
WH3_k127_592912_2 - - - - 0.0000000557 56.0
WH3_k127_5932947_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 457.0
WH3_k127_5932947_1 COG1305 Transglutaminase-like enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 416.0
WH3_k127_5932947_2 proteasome-type protease K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 402.0
WH3_k127_5932947_3 Circularly permuted ATP-grasp type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 386.0
WH3_k127_5932947_4 Extensin-like protein C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 297.0
WH3_k127_5932947_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004872 248.0
WH3_k127_5932947_6 lactoylglutathione lyase activity - - - 0.0000000000000004412 79.0
WH3_k127_5932947_7 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.00003284 48.0
WH3_k127_5964611_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 5.345e-244 759.0
WH3_k127_5964611_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 317.0
WH3_k127_5964611_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009364 257.0
WH3_k127_596837_0 Bacterial protein of unknown function (DUF853) K06915 - - 5.001e-279 864.0
WH3_k127_596837_1 aminopeptidase K01262 - 3.4.11.9 7.619e-272 849.0
WH3_k127_596837_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000001084 72.0
WH3_k127_596837_11 peptidase S9 K01354 - 3.4.21.83 0.0000005263 51.0
WH3_k127_596837_2 component I K01665,K03342 - 2.6.1.85,4.1.3.38 2.109e-266 837.0
WH3_k127_596837_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 501.0
WH3_k127_596837_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 377.0
WH3_k127_596837_5 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 331.0
WH3_k127_596837_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000003511 201.0
WH3_k127_596837_7 chain release factor K15034 - - 0.000000000000000000000000000000000000000000000002407 177.0
WH3_k127_596837_8 EF-hand, calcium binding motif - - - 0.000000000000000000000000000000002662 137.0
WH3_k127_596837_9 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000002145 108.0
WH3_k127_5986738_0 protein conserved in bacteria K09919 - - 1.345e-194 615.0
WH3_k127_5986738_1 glycerophosphoryl diester phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 328.0
WH3_k127_5986738_2 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000002427 157.0
WH3_k127_5986738_3 endoribonuclease - - - 0.000000000000004649 75.0
WH3_k127_6026305_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 581.0
WH3_k127_6026305_1 Glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000002569 143.0
WH3_k127_6026305_2 Putative zinc binding domain - - - 0.000000000000001897 76.0
WH3_k127_6113329_0 protein conserved in bacteria K09800 - - 0.0 1152.0
WH3_k127_6113329_1 COG0729 Outer membrane protein K07278 - - 3.714e-246 786.0
WH3_k127_6113329_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 458.0
WH3_k127_6120362_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 443.0
WH3_k127_6120362_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 351.0
WH3_k127_6120362_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002636 252.0
WH3_k127_6120362_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000482 199.0
WH3_k127_6143657_0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 2.702e-243 757.0
WH3_k127_6143657_1 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 5.056e-216 674.0
WH3_k127_6143657_10 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000006342 57.0
WH3_k127_6143657_2 dihydropteroate synthase K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 522.0
WH3_k127_6143657_3 NAD(P) transhydrogenase subunit alpha K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 464.0
WH3_k127_6143657_4 ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 390.0
WH3_k127_6143657_5 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 343.0
WH3_k127_6143657_6 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 316.0
WH3_k127_6143657_7 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 300.0
WH3_k127_6143657_8 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000001082 198.0
WH3_k127_6149415_0 peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 549.0
WH3_k127_6149415_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 394.0
WH3_k127_6149415_2 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000000000000000000001062 138.0
WH3_k127_6170762_0 Respiratory nitrate reductase beta C-terminal - - - 6.345e-267 822.0
WH3_k127_6170762_1 PPIC-type PPIASE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 376.0
WH3_k127_6170762_2 Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 363.0
WH3_k127_6170762_3 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 343.0
WH3_k127_6170762_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate - - - 0.0002817 44.0
WH3_k127_6177950_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 550.0
WH3_k127_6177950_1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis K11740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 531.0
WH3_k127_6177950_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 439.0
WH3_k127_6177950_3 Domain of unknown function DUF87 K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 432.0
WH3_k127_6177950_4 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 366.0
WH3_k127_6177950_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002127 248.0
WH3_k127_6177950_6 - - - - 0.000000000000000000000000000000000000000000000000000000000009504 224.0
WH3_k127_6194431_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 374.0
WH3_k127_6194431_1 5-aminolevulinic acid synthase K00643 - 2.3.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 350.0
WH3_k127_6194431_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000003132 147.0
WH3_k127_6203404_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 5.254e-258 807.0
WH3_k127_6203404_1 ATPase with chaperone activity K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 527.0
WH3_k127_6203404_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 344.0
WH3_k127_6203404_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 318.0
WH3_k127_6203404_4 periplasmic protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002506 262.0
WH3_k127_6203404_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000000000000000000000000641 179.0
WH3_k127_6203404_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000000000002306 146.0
WH3_k127_6203404_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000002626 79.0
WH3_k127_6213911_0 Chain-length determining protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 613.0
WH3_k127_6213911_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 590.0
WH3_k127_6213911_2 polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 356.0
WH3_k127_6213911_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000007415 185.0
WH3_k127_6213911_4 involved in chromosome partitioning - - - 0.00000000000000001864 87.0
WH3_k127_6223992_0 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.122e-208 663.0
WH3_k127_6223992_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 524.0
WH3_k127_6223992_2 synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 486.0
WH3_k127_6223992_3 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 338.0
WH3_k127_6223992_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000005619 168.0
WH3_k127_6252636_0 Peptidase family M3 K01284 - 3.4.15.5 0.0 1049.0
WH3_k127_6262019_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 477.0
WH3_k127_6262019_1 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 378.0
WH3_k127_6282222_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 1.061e-267 835.0
WH3_k127_6282222_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 531.0
WH3_k127_6282222_2 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 504.0
WH3_k127_6282222_3 ArsR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 431.0
WH3_k127_6282222_4 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 393.0
WH3_k127_6283906_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1051.0
WH3_k127_6283906_1 peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 553.0
WH3_k127_6283906_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 446.0
WH3_k127_6283906_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 361.0
WH3_k127_6313964_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 499.0
WH3_k127_6313964_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 428.0
WH3_k127_6313964_2 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 392.0
WH3_k127_6313964_3 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 378.0
WH3_k127_6313964_4 Domain of unknown function (DUF3333) K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 314.0
WH3_k127_6369693_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 400.0
WH3_k127_6369693_1 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 399.0
WH3_k127_6369693_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 329.0
WH3_k127_6369693_3 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003345 280.0
WH3_k127_6369693_4 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002088 247.0
WH3_k127_6374177_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.274e-279 863.0
WH3_k127_6392272_0 Heat shock 70 kDa protein K04043 - - 4.578e-287 884.0
WH3_k127_6392272_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001504 261.0
WH3_k127_6392272_2 Pfam:DUF461 K09796 - - 0.000000000000000000000000000000000000000006927 160.0
WH3_k127_6393581_0 Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate K06447 - 1.2.1.71 1.63e-229 714.0
WH3_k127_6393581_1 - - - - 0.000000000000000000000000000000000000000000000000000003672 204.0
WH3_k127_6393581_2 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000002512 135.0
WH3_k127_6490255_0 Belongs to the ClpA ClpB family K03694 - - 2.185e-237 737.0
WH3_k127_6490255_1 NADPH quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 479.0
WH3_k127_6490255_2 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000008283 135.0
WH3_k127_6490255_3 Protein of unknown function (DUF1192) - - - 0.00000000000000000001075 94.0
WH3_k127_649715_0 Belongs to the GPI family K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 3.743e-250 780.0
WH3_k127_649715_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 1.913e-227 713.0
WH3_k127_649715_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 347.0
WH3_k127_649715_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 306.0
WH3_k127_649715_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000001972 197.0
WH3_k127_6518297_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 491.0
WH3_k127_6518297_1 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 484.0
WH3_k127_6518297_2 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.000000000000000000000000000000000000000000000000000000004465 203.0
WH3_k127_6518297_3 Dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000003839 120.0
WH3_k127_6518297_4 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000005004 89.0
WH3_k127_6518297_5 membrane K09650 - 3.4.21.105 0.000002998 49.0
WH3_k127_6592204_0 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 458.0
WH3_k127_6592204_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 412.0
WH3_k127_6592204_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000006713 120.0
WH3_k127_6592204_3 - - - - 0.000000000000006255 80.0
WH3_k127_6611440_0 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 369.0
WH3_k127_6611440_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003058 269.0
WH3_k127_6611440_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009544 263.0
WH3_k127_6611440_3 - - - - 0.00000000000000000000000000000000001265 137.0
WH3_k127_6638080_0 glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 491.0
WH3_k127_6638080_1 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001111 282.0
WH3_k127_6638080_2 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000225 213.0
WH3_k127_6645686_0 Methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 439.0
WH3_k127_6645686_1 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 419.0
WH3_k127_6645686_2 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001053 268.0
WH3_k127_6659787_0 dehydratase K07749 - 2.8.3.16 6.2e-217 680.0
WH3_k127_6659787_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000144 205.0
WH3_k127_6659787_2 MazG family K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000387 168.0
WH3_k127_6678550_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1462.0
WH3_k127_6678550_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 511.0
WH3_k127_6681906_0 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 412.0
WH3_k127_6681906_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001878 241.0
WH3_k127_6681906_2 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000007413 207.0
WH3_k127_6681906_3 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000585 204.0
WH3_k127_6681906_4 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000002836 156.0
WH3_k127_6681906_5 CoA binding domain - - - 0.00000000000000000000000000000000006308 142.0
WH3_k127_6759426_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 5.264e-251 777.0
WH3_k127_6759426_1 synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 591.0
WH3_k127_6759426_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000009143 80.0
WH3_k127_6784604_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.197e-270 837.0
WH3_k127_6784604_1 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 3.787e-198 625.0
WH3_k127_6784604_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 295.0
WH3_k127_6791007_0 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 452.0
WH3_k127_6791007_1 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000000000000000000000000000000000000000007495 217.0
WH3_k127_6791007_2 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000001129 157.0
WH3_k127_6796717_0 synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 565.0
WH3_k127_6796717_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 559.0
WH3_k127_6796717_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 469.0
WH3_k127_6796717_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002682 273.0
WH3_k127_6796717_4 MerC mercury resistance protein - - - 0.0000000000000000000000000000000000000000000000000009009 186.0
WH3_k127_6796717_5 - - - - 0.000002453 53.0
WH3_k127_681265_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 533.0
WH3_k127_681265_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 467.0
WH3_k127_681265_2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000007452 65.0
WH3_k127_6901216_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 3.706e-226 709.0
WH3_k127_6901216_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 5.52e-196 614.0
WH3_k127_6901216_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 312.0
WH3_k127_6901216_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000162 93.0
WH3_k127_6964749_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 322.0
WH3_k127_6964749_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000004132 237.0
WH3_k127_7013693_0 TonB dependent receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000000006822 224.0
WH3_k127_7013693_1 Cell Wall - - - 0.00000000000004949 78.0
WH3_k127_7017144_0 2-hydroxychromene-2-carboxylate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 342.0
WH3_k127_7017144_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000154 280.0
WH3_k127_7017144_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000005866 222.0
WH3_k127_7017144_3 - - - - 0.00000000000000000000000001753 117.0
WH3_k127_7024301_0 Aerobic cobaltochelatase subunit CobS K09882 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 398.0
WH3_k127_7024301_1 pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002282 269.0
WH3_k127_7024301_2 protein, possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000004495 234.0
WH3_k127_7024301_3 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000003593 172.0
WH3_k127_7024301_4 lyase activity - - - 0.000000000000000000000000000000000000000001743 168.0
WH3_k127_7037807_0 membrane K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 594.0
WH3_k127_7037807_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 346.0
WH3_k127_7037807_2 Protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000921 237.0
WH3_k127_7037807_3 Protein of unknown function (DUF2497) K09991 - - 0.00000000000000000000000000000000000000000005093 166.0
WH3_k127_7037807_4 peptidase S9 - - - 0.0000000000000000004752 96.0
WH3_k127_7067637_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 604.0
WH3_k127_7067637_1 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 524.0
WH3_k127_7067637_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 348.0
WH3_k127_7067637_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 348.0
WH3_k127_7067637_4 In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 349.0
WH3_k127_7067637_5 - - - - 0.0000000001514 64.0
WH3_k127_7077284_0 COG2070 Dioxygenases related to 2-nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 606.0
WH3_k127_7077284_1 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 569.0
WH3_k127_7077284_2 transcriptional regulator - - - 0.0000000000000000000000000000000000001172 143.0
WH3_k127_7100516_0 DNA helicase K03657 - 3.6.4.12 7.844e-208 651.0
WH3_k127_7100516_1 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000000000000000000001853 266.0
WH3_k127_710470_0 Carboxypeptidase - - - 6.437e-196 616.0
WH3_k127_710470_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 570.0
WH3_k127_710470_2 Hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002961 261.0
WH3_k127_710470_3 - - - - 0.000000000000000000000000000000000000000000000000000000005267 205.0
WH3_k127_710470_4 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000000972 80.0
WH3_k127_710470_5 response regulator K11443 - - 0.00000008033 55.0
WH3_k127_7113261_0 acyl-CoA dehydrogenase K20035 - - 2.721e-300 929.0
WH3_k127_7113261_1 sorbosone - - - 6.974e-211 665.0
WH3_k127_7113261_2 GAF domain-containing protein K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000000000002145 245.0
WH3_k127_7113261_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000007337 159.0
WH3_k127_7128749_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.0 1090.0
WH3_k127_7128749_1 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 2.883e-212 664.0
WH3_k127_7128749_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 3.359e-198 627.0
WH3_k127_7128749_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 581.0
WH3_k127_7128749_4 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 468.0
WH3_k127_7128749_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000003681 240.0
WH3_k127_7128749_6 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001324 235.0
WH3_k127_7128749_7 Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000001106 233.0
WH3_k127_7128749_8 Protein of unknown function (DUF2842) - - - 0.0000000000000000000005181 98.0
WH3_k127_7128749_9 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000004786 83.0
WH3_k127_7135732_0 Involved in the TonB-independent uptake of proteins K03641 - - 6.72e-210 654.0
WH3_k127_7135732_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 473.0
WH3_k127_7135732_2 molecular chaperone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 297.0
WH3_k127_7135732_3 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003096 246.0
WH3_k127_7147316_0 COG3210 Large exoproteins involved in heme utilization or adhesion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 406.0
WH3_k127_7186124_0 Ubiquinol-cytochrome C chaperone K17662 - - 0.00000000000000000000000000000000000000000000000000000165 198.0
WH3_k127_7186124_1 Uncharacterized ACR, COG1399 - - - 0.0000000000000000000000000000000000000000000003406 174.0
WH3_k127_7214691_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 6.253e-194 608.0
WH3_k127_7214691_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 314.0
WH3_k127_7214691_2 Alkyl hydroperoxide reductase K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.11.1.15 0.000000000000129 73.0
WH3_k127_7243730_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 486.0
WH3_k127_7243730_1 Protein of unknown function (DUF3376) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005385 239.0
WH3_k127_724688_0 Uncharacterized ACR, YdiU/UPF0061 family - - - 5.371e-236 738.0
WH3_k127_724688_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 370.0
WH3_k127_724688_2 Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate K06447 - 1.2.1.71 0.00000000000000000000000000000000000000000000000000000000000000000004032 233.0
WH3_k127_724688_3 Glycosyl transferase family 1 - - - 0.00000000000000000000000000002865 121.0
WH3_k127_7279600_0 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 350.0
WH3_k127_7279600_1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 337.0
WH3_k127_7279600_2 Protein conserved in bacteria K11719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 316.0
WH3_k127_7279600_3 protein conserved in bacteria K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004366 246.0
WH3_k127_7307580_0 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 593.0
WH3_k127_7307580_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 601.0
WH3_k127_7307580_2 B-1 B cell differentiation - - - 0.0000000000000000000000000000000000000000000000000000000000000000006546 243.0
WH3_k127_7353382_0 Belongs to the thiolase family K00626 - 2.3.1.9 5.098e-221 689.0
WH3_k127_7353382_1 carnitine dehydratase K14470 - 5.4.1.3 6.648e-198 629.0
WH3_k127_7353382_2 acyl-CoA dehydrogenase K06446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 614.0
WH3_k127_7353382_3 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 562.0
WH3_k127_7353382_4 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 415.0
WH3_k127_7353382_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 344.0
WH3_k127_7353382_6 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000001338 217.0
WH3_k127_7353382_7 - - - - 0.00000000000000002947 84.0
WH3_k127_7353382_8 Transglycosylase associated protein - - - 0.00000000000002373 82.0
WH3_k127_7353382_9 - - - - 0.00000000001934 68.0
WH3_k127_7388486_0 protein conserved in bacteria - - - 2e-323 1011.0
WH3_k127_7388486_1 COG2831 Hemolysin activation secretion protein - - - 1.335e-200 642.0
WH3_k127_7388486_2 COG3210 Large exoproteins involved in heme utilization or adhesion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004548 267.0
WH3_k127_7404774_0 Asparagine synthase K01953 - 6.3.5.4 1.545e-315 974.0
WH3_k127_7404774_1 AFG1 family ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 576.0
WH3_k127_7404774_2 enoyl-CoA hydratase K13816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 477.0
WH3_k127_7404774_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 360.0
WH3_k127_7453047_0 Cysteine synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 604.0
WH3_k127_7453047_1 ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000000000007169 194.0
WH3_k127_7453047_2 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000005208 162.0
WH3_k127_7453047_3 - - - - 0.00000000000000000000000000000000000000000524 163.0
WH3_k127_7453047_4 - - - - 0.00000000000000001822 86.0
WH3_k127_7457408_0 Chalcone and stilbene synthases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 385.0
WH3_k127_7457408_1 periplasmic protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 314.0
WH3_k127_7457408_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001502 224.0
WH3_k127_7499810_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 1.995e-263 818.0
WH3_k127_7511358_0 Flp pilus assembly protein, ATPase CpaF K02283 - - 3.441e-271 837.0
WH3_k127_7511358_1 dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 591.0
WH3_k127_7511358_10 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000004077 152.0
WH3_k127_7511358_11 - - - - 0.0000000000000000000000000000209 121.0
WH3_k127_7511358_12 - - - - 0.00000000000000474 87.0
WH3_k127_7511358_13 response to toxic substance K16348 - - 0.00000000001398 65.0
WH3_k127_7511358_2 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 587.0
WH3_k127_7511358_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 439.0
WH3_k127_7511358_4 Alpha beta hydrolase K18092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 414.0
WH3_k127_7511358_5 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 313.0
WH3_k127_7511358_6 aspartate racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 303.0
WH3_k127_7511358_7 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000397 279.0
WH3_k127_7511358_8 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000042 282.0
WH3_k127_7511358_9 Domain of unknown function (DUF4281) - - - 0.0000000000000000000000000000000000000000000000000000000000005962 214.0
WH3_k127_7589845_0 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 526.0
WH3_k127_7589845_1 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 459.0
WH3_k127_7589845_2 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 434.0
WH3_k127_7589845_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 379.0
WH3_k127_7589845_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000005102 205.0
WH3_k127_7602854_0 S1/P1 Nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 317.0
WH3_k127_7602854_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001212 259.0
WH3_k127_7602854_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005493 248.0
WH3_k127_7602854_3 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000005697 241.0
WH3_k127_7602854_4 S1/P1 Nuclease - - - 0.00000000000000000000000005918 111.0
WH3_k127_7617623_0 COG2366 Protein related to penicillin acylase K07116 - 3.5.1.97 1.24e-322 1000.0
WH3_k127_7617623_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 451.0
WH3_k127_7626600_0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 423.0
WH3_k127_7626600_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 316.0
WH3_k127_7626600_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000001141 248.0
WH3_k127_7626600_3 Bacterial PH domain K09167 - - 0.00000000000000000000000000000000000000000000000000000005586 203.0
WH3_k127_7626600_4 Bacterial PH domain - - - 0.00000000000000003301 86.0
WH3_k127_7671376_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 8.197e-233 737.0
WH3_k127_7671376_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 8.358e-230 723.0
WH3_k127_7671376_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 335.0
WH3_k127_7671376_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002489 278.0
WH3_k127_7693837_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.261e-269 832.0
WH3_k127_7693837_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 413.0
WH3_k127_7693837_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 308.0
WH3_k127_7693837_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000000000008971 160.0
WH3_k127_7728128_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 552.0
WH3_k127_7728128_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 312.0
WH3_k127_7728128_2 - - - - 0.000000000449 66.0
WH3_k127_7741287_0 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 450.0
WH3_k127_7741287_1 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000000000000000000000000000007865 227.0
WH3_k127_7741287_2 - - - - 0.000000000000001984 80.0
WH3_k127_7777672_0 Serine aminopeptidase, S33 K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 458.0
WH3_k127_7777672_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000004975 155.0
WH3_k127_778978_0 Type II secretory pathway, component ExeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 475.0
WH3_k127_778978_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 449.0
WH3_k127_778978_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000001592 184.0
WH3_k127_7801977_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 385.0
WH3_k127_7801977_1 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 319.0
WH3_k127_7801977_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000008257 248.0
WH3_k127_7801977_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000008986 194.0
WH3_k127_7802743_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 8.613e-289 905.0
WH3_k127_7802743_1 Saccharopine dehydrogenase NADP binding domain - - - 5.206e-198 624.0
WH3_k127_7802743_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000008349 200.0
WH3_k127_7802743_3 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000407 159.0
WH3_k127_7802743_4 - - - - 0.000000001106 61.0
WH3_k127_7849104_0 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 340.0
WH3_k127_7849104_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001146 290.0
WH3_k127_7849104_2 Beta-lactamase enzyme family K07262 - - 0.0000000000000000000000000000000000000000000000000002616 190.0
WH3_k127_7849104_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000001184 190.0
WH3_k127_7850741_0 - - - - 0.0 1005.0
WH3_k127_7850741_1 Haem-degrading - - - 4.152e-252 786.0
WH3_k127_7850741_2 LVIVD repeat - - - 0.0000002755 59.0
WH3_k127_7860576_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 555.0
WH3_k127_7860576_1 Tyrosine phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 332.0
WH3_k127_7860576_2 MAPEG family - - - 0.00000000000000000000000000000000000000000000000000000000000000008343 225.0
WH3_k127_7860576_3 MAPEG family - - - 0.00000000000000000000000000000000000000000000000000000000000001139 222.0
WH3_k127_7860576_4 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000003755 85.0
WH3_k127_7866789_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 533.0
WH3_k127_7866789_1 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 439.0
WH3_k127_7866789_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 308.0
WH3_k127_7866789_3 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 301.0
WH3_k127_7866789_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000007553 259.0
WH3_k127_7866789_5 Domain of unknown function (DUF1508) K09946 - - 0.000000000000000000000000002303 111.0
WH3_k127_7885597_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.351e-291 898.0
WH3_k127_7885597_1 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 304.0
WH3_k127_7885597_2 endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 283.0
WH3_k127_7969490_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 6.136e-197 627.0
WH3_k127_8014151_0 helicase K16899 - 3.6.4.12 0.0 1337.0
WH3_k127_8014151_1 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 583.0
WH3_k127_8014151_2 Phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 454.0
WH3_k127_8014151_3 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 406.0
WH3_k127_8014151_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 361.0
WH3_k127_8014151_5 ATPase or kinase K06925 - - 0.000000000000000000000000000000000000000000000000000000000000000007212 230.0
WH3_k127_8147829_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 531.0
WH3_k127_8147829_1 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000001894 204.0
WH3_k127_8147829_2 - - - - 0.00000000000000000000000002834 112.0
WH3_k127_8147829_3 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000000000004519 106.0
WH3_k127_8154443_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.354e-261 805.0
WH3_k127_8154443_1 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 1.682e-255 793.0
WH3_k127_8154443_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 436.0
WH3_k127_8154443_3 NADH dehydrogenase K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 429.0
WH3_k127_8154443_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009464 368.0
WH3_k127_8154443_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 357.0
WH3_k127_8154443_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000003543 224.0
WH3_k127_8154443_7 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000005699 182.0
WH3_k127_8169194_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.655e-241 747.0
WH3_k127_8169194_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 345.0
WH3_k127_8201151_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.75e-265 821.0
WH3_k127_8201151_1 COG1226 Kef-type K transport systems K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 576.0
WH3_k127_8201151_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 414.0
WH3_k127_8201151_3 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 330.0
WH3_k127_8201151_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003215 266.0
WH3_k127_8201151_5 Protein of unknown function (DUF1761) - - - 0.00000000000000000000000000000000000000000000001681 173.0
WH3_k127_820770_0 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 422.0
WH3_k127_820770_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000122 50.0
WH3_k127_821973_0 cystathionine beta-lyase K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 496.0
WH3_k127_821973_1 Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 316.0
WH3_k127_821973_2 - - - - 0.00000000000000000000000002524 118.0
WH3_k127_8224988_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 9.135e-304 939.0
WH3_k127_8224988_1 DNA polymerase III K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000003323 254.0
WH3_k127_8224988_2 Lipopolysaccharide-assembly K03643 - - 0.0000000000000000000000000000000000000000000000000000000000000004507 226.0
WH3_k127_8299094_0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 3.951e-303 933.0
WH3_k127_8299094_1 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 528.0
WH3_k127_8299094_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000001996 213.0
WH3_k127_8331271_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 6.77e-212 662.0
WH3_k127_8331271_1 Protein of unknown function (DUF2855) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 480.0
WH3_k127_8331271_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 415.0
WH3_k127_8331271_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000002529 168.0
WH3_k127_8335858_0 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.0 1555.0
WH3_k127_8335858_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 313.0
WH3_k127_8335858_2 endonuclease containing a URI domain K07461 - - 0.0000000000000000000000000000002828 124.0
WH3_k127_8347968_0 2-nitropropane dioxygenase - - - 8.726e-274 845.0
WH3_k127_8347968_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 524.0
WH3_k127_8347968_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 353.0
WH3_k127_8392544_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 1.528e-222 705.0
WH3_k127_8392544_1 Extracellular solute-binding protein - - - 0.000000000000000000000000000004059 122.0
WH3_k127_8403141_0 Peptidase, M16 - - - 4.195e-284 890.0
WH3_k127_8403141_1 Signal peptide protein - - - 0.00000000000000000000000000000000000000000000003781 172.0
WH3_k127_841338_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 441.0
WH3_k127_841338_1 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 422.0
WH3_k127_841338_2 - - - - 0.000000000000000000000000000002796 121.0
WH3_k127_841338_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K07812 - 1.7.2.3,1.8.5.3 0.0000007156 60.0
WH3_k127_846886_0 de-polymerase K05973 - 3.1.1.75 7.094e-202 635.0
WH3_k127_846886_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 529.0
WH3_k127_846886_2 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
WH3_k127_847188_0 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 315.0
WH3_k127_847188_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005727 252.0
WH3_k127_847188_2 thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000000002391 235.0
WH3_k127_847188_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000005353 223.0
WH3_k127_847188_4 Biopolymer transport protein K03560 - - 0.0000000000000000000000000000000000000000000000000001192 189.0
WH3_k127_847188_5 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.0000000000000000000000000000000000001268 143.0
WH3_k127_8581657_0 Glycosyl-hydrolase 97 C-terminal, oligomerisation K01187 - 3.2.1.20 0.0 1114.0
WH3_k127_8581657_1 Alpha-amylase domain K01187 - 3.2.1.20 2.127e-262 817.0
WH3_k127_8581657_2 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000002075 158.0
WH3_k127_8581657_3 Alpha-amylase domain - - - 0.000000000000000000000002244 104.0
WH3_k127_8597272_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1087.0
WH3_k127_8597272_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0 1053.0
WH3_k127_8597272_2 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 458.0
WH3_k127_8597272_3 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 322.0
WH3_k127_8639997_0 Phosphate ABC transporter substrate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 525.0
WH3_k127_8639997_1 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 452.0
WH3_k127_8639997_2 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 319.0
WH3_k127_8639997_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000004037 191.0
WH3_k127_8640041_0 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 398.0
WH3_k127_8640041_1 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 368.0
WH3_k127_8640041_2 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 347.0
WH3_k127_8640041_3 Histidine phosphotransferase C-terminal domain K13588 - - 0.0000000000000000000000000000000000000000000000000000000000000006532 221.0
WH3_k127_8640041_4 COG0346 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000001651 198.0
WH3_k127_8640041_5 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000215 191.0
WH3_k127_8640041_6 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.0000000000000000000000000000000000000004399 151.0
WH3_k127_8781250_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 531.0
WH3_k127_8781250_1 phosphate-selective porin K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 509.0
WH3_k127_8781250_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 473.0
WH3_k127_8781250_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 437.0
WH3_k127_8781250_4 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 313.0
WH3_k127_8781250_5 Protein of unknown function (DUF2794) - - - 0.00000000000000000000000000000000000000000000000001794 180.0
WH3_k127_8794594_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0 1144.0
WH3_k127_8794594_1 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 540.0
WH3_k127_8794594_2 BetI-type transcriptional repressor, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006842 240.0
WH3_k127_8877095_0 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 418.0
WH3_k127_8877095_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 412.0
WH3_k127_8889554_0 ABC-type oligopeptide transport system, periplasmic component K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 546.0
WH3_k127_8889554_1 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001023 256.0
WH3_k127_8889554_2 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000000000000003818 143.0
WH3_k127_8889554_3 PilZ domain - - - 0.000000000000000000000000000000000004345 141.0
WH3_k127_8919775_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 3.477e-195 617.0
WH3_k127_8919775_1 synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 596.0
WH3_k127_8919775_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000005736 227.0
WH3_k127_8919775_3 Pilus assembly protein PilZ - - - 0.00000000000000000000000000000000000000000000000000003821 192.0
WH3_k127_8926622_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 455.0
WH3_k127_8926622_1 enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 373.0
WH3_k127_8969839_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 4.049e-234 729.0
WH3_k127_8969839_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 608.0
WH3_k127_8969839_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 424.0
WH3_k127_8969839_3 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 397.0
WH3_k127_8969839_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 367.0
WH3_k127_8978974_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 358.0
WH3_k127_8978974_1 Leucine-rich repeat (LRR) protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001407 295.0
WH3_k127_8978974_2 B-1 B cell differentiation K00650 - 2.3.1.43 0.00000000000000000000000000000000093 138.0
WH3_k127_8978974_3 TIR domain - - - 0.000000001211 60.0
WH3_k127_8999603_0 coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 512.0
WH3_k127_8999603_1 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 373.0
WH3_k127_8999603_2 ICC-like phosphoesterases K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 351.0
WH3_k127_8999603_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 299.0
WH3_k127_8999603_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000008727 263.0
WH3_k127_8999603_5 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000004049 57.0
WH3_k127_9041033_0 AMP-binding enzyme C-terminal domain K00666 - - 2.486e-213 673.0
WH3_k127_9041033_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.548e-195 622.0
WH3_k127_9041033_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 391.0
WH3_k127_9041033_3 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000182 268.0
WH3_k127_9041033_4 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000006147 241.0
WH3_k127_9041033_5 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001928 239.0
WH3_k127_9089871_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 388.0
WH3_k127_9089871_1 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006608 246.0
WH3_k127_9089871_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000003633 178.0
WH3_k127_9089871_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000000001631 148.0
WH3_k127_9098243_0 receptor - - - 6.205e-287 892.0
WH3_k127_9098243_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 446.0
WH3_k127_9098243_2 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane K11103 - - 0.000000000000000000000000000001625 121.0
WH3_k127_9106076_0 rod shape-determining protein MreB K03569 - - 7.046e-201 631.0
WH3_k127_9106076_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 379.0
WH3_k127_9106076_2 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000001624 189.0
WH3_k127_9125388_0 peptidase M13 K07386 - - 1.309e-306 954.0
WH3_k127_9125388_1 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000001237 205.0
WH3_k127_9125388_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000009774 171.0
WH3_k127_9134658_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 526.0
WH3_k127_9134658_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 483.0
WH3_k127_9134658_2 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006195 288.0
WH3_k127_9134658_3 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003386 280.0
WH3_k127_9134658_4 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002568 260.0
WH3_k127_9134658_5 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000345 248.0
WH3_k127_9134658_6 Erythromycin esterase - - - 0.000000000000003971 74.0
WH3_k127_9135784_0 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 328.0
WH3_k127_9135784_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 311.0
WH3_k127_9135784_2 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001248 276.0
WH3_k127_9135784_3 - - - - 0.0000000000000000000000000000000000000000000000000000000004618 212.0
WH3_k127_9135784_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001547 171.0
WH3_k127_9151786_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 608.0
WH3_k127_9151786_1 Iron-regulated membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 336.0
WH3_k127_9151786_2 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 287.0
WH3_k127_9151786_3 dioxygenase of extradiol dioxygenase family K06991 - - 0.000000000000000000000000000000000000000000000000000000000000002917 222.0
WH3_k127_9151786_4 - - - - 0.00000000000000000000000000000000000000000000002592 179.0
WH3_k127_9151786_5 - - - - 0.0000000000000982 72.0
WH3_k127_9167827_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 579.0
WH3_k127_9167827_1 protein conserved in bacteria K09973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 362.0
WH3_k127_9167827_2 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001123 284.0
WH3_k127_9167827_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000002803 247.0
WH3_k127_9212395_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 340.0
WH3_k127_9212395_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006857 244.0
WH3_k127_9226802_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 0.0 1154.0
WH3_k127_9226802_1 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 462.0
WH3_k127_9226802_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 290.0
WH3_k127_9226802_3 RDD family - - - 0.0000000000000000000000000000000000000000000005597 170.0
WH3_k127_9236050_0 ABC transporter permease K05845,K05846 - - 7.197e-228 717.0
WH3_k127_9236050_1 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 5.232e-200 639.0
WH3_k127_9236050_10 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000002858 232.0
WH3_k127_9236050_11 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000295 143.0
WH3_k127_9236050_2 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 457.0
WH3_k127_9236050_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 413.0
WH3_k127_9236050_4 Putative S-adenosyl-L-methionine-dependent methyltransferase K18164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 389.0
WH3_k127_9236050_5 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 379.0
WH3_k127_9236050_6 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 357.0
WH3_k127_9236050_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 348.0
WH3_k127_9236050_8 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 288.0
WH3_k127_9236050_9 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000742 269.0
WH3_k127_9282566_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.533e-253 784.0
WH3_k127_9282566_1 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000007814 245.0
WH3_k127_931371_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 572.0
WH3_k127_931371_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 565.0
WH3_k127_931371_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 477.0
WH3_k127_931371_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 374.0
WH3_k127_931371_4 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 372.0
WH3_k127_931371_5 depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004498 263.0
WH3_k127_931371_6 Flp pilus assembly protein, ATPase CpaF K02283 - - 0.00000000000000000007185 92.0
WH3_k127_932871_0 Subtilase family - - - 1.941e-263 834.0
WH3_k127_932871_1 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 588.0
WH3_k127_932871_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000005407 186.0
WH3_k127_9376899_0 Alpha Beta K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 428.0
WH3_k127_9376899_1 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0009065 44.0
WH3_k127_9377017_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 541.0
WH3_k127_9377017_1 RarD protein K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 336.0
WH3_k127_9377017_2 EamA-like transporter family K15268 - - 0.0000000000000000000000000000001864 127.0
WH3_k127_9402498_0 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 332.0
WH3_k127_9402498_1 Hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003473 273.0
WH3_k127_9402498_2 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.000000000000000000000000000000003507 132.0
WH3_k127_9402498_3 - - - - 0.000000000864 64.0
WH3_k127_9475489_0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 296.0
WH3_k127_9475489_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 293.0
WH3_k127_9475489_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004615 271.0
WH3_k127_9475489_3 - - - - 0.000000000000000000003466 96.0
WH3_k127_9475489_4 - - - - 0.0000000000000002207 85.0
WH3_k127_9497843_0 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 473.0
WH3_k127_9497843_1 Prolyl oligopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 428.0
WH3_k127_9497843_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 390.0
WH3_k127_9497843_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003031 260.0
WH3_k127_9497843_4 - - - - 0.0000000000000000002572 87.0
WH3_k127_9512886_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 1.272e-245 763.0
WH3_k127_9512886_1 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 359.0
WH3_k127_9512886_2 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001936 243.0
WH3_k127_9512886_3 Nickel/cobalt transporter regulator - - - 0.00000000000000000000000000000000000000000000000001257 186.0
WH3_k127_9518413_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 1.127e-274 852.0
WH3_k127_9518413_1 OmpW family K07275 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 333.0
WH3_k127_9518413_2 leukotriene A-4 hydrolase - - - 0.000000000000000000000000000000009343 128.0
WH3_k127_9520799_0 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase K06147 - - 4.93e-291 904.0
WH3_k127_9520799_1 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 533.0
WH3_k127_9520799_2 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 321.0
WH3_k127_9520799_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000002385 158.0
WH3_k127_9546306_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 484.0
WH3_k127_9546306_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 289.0
WH3_k127_9546306_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006291 257.0
WH3_k127_9621325_0 TrbL/VirB6 plasmid conjugal transfer protein K03201 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 417.0
WH3_k127_9621325_1 Conjugal transfer protein K03204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 324.0
WH3_k127_9621325_2 type IV secretion system K03199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 301.0
WH3_k127_9621325_3 Bacterial conjugation TrbI-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002194 246.0
WH3_k127_9641907_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.625e-312 966.0
WH3_k127_9641907_1 acyl-CoA dehydrogenase K00252 - 1.3.8.6 3.694e-235 731.0
WH3_k127_9641907_2 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 507.0
WH3_k127_9641907_3 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 291.0
WH3_k127_9641907_4 OmpA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001023 258.0
WH3_k127_9641907_5 rRNA binding - - - 0.000000000000000000000000000000000000000000000002487 179.0
WH3_k127_9653297_0 Sulfite reductase K00381 - 1.8.1.2 7.113e-306 945.0
WH3_k127_9653297_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 591.0
WH3_k127_9653297_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 469.0
WH3_k127_9653297_3 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 434.0
WH3_k127_9653297_4 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 407.0
WH3_k127_9653297_5 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 377.0
WH3_k127_9653297_6 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 368.0
WH3_k127_9653297_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000003323 203.0
WH3_k127_9653297_8 Protein of unknown function (DUF2849) - - - 0.0000000000000000000000000000000000001779 149.0
WH3_k127_9653297_9 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000008282 57.0
WH3_k127_9665328_0 Protein of unknown function (DUF1800) - - - 1.294e-241 761.0
WH3_k127_9665328_1 Tat pathway signal protein - - - 0.000000000000000000000000000000000000000000000000000006082 193.0
WH3_k127_9665328_2 FAD dependent oxidoreductase K07137 - - 0.000000000000000000000000000000000119 133.0
WH3_k127_9809313_0 peptidase U62, modulator of DNA gyrase K03568 - - 3.07e-272 841.0
WH3_k127_9809313_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 527.0
WH3_k127_9809313_2 Domain of unknown function (DUF4402) - - - 0.0000000000000000000000000000000000000001667 158.0
WH3_k127_9809313_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000003327 142.0
WH3_k127_9809313_4 - - - - 0.000000000000000000000005373 108.0
WH3_k127_9809313_5 Domain of unknown function (DUF4402) - - - 0.000000000000001889 87.0
WH3_k127_9809313_6 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00006446 47.0
WH3_k127_9833893_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.007e-236 739.0
WH3_k127_9833893_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 9.757e-221 698.0
WH3_k127_9833893_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 435.0
WH3_k127_9833893_3 CHAP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004423 247.0
WH3_k127_9833893_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000004426 194.0
WH3_k127_9833893_5 Protein of unknown function (DUF3297) - - - 0.000000000000000000000000000000000000000000001033 167.0
WH3_k127_9833893_6 - - - - 0.000000000000000000008115 94.0
WH3_k127_9833893_7 - - - - 0.00000004244 61.0
WH3_k127_9848090_0 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 433.0
WH3_k127_9848090_1 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 430.0
WH3_k127_9848090_2 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 403.0
WH3_k127_9848090_3 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 394.0
WH3_k127_9848090_4 - - - - 0.0000000000000000000000000000000002169 146.0
WH3_k127_989477_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 1.02e-211 664.0
WH3_k127_989477_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 407.0
WH3_k127_989477_2 acyl carrier protein - - - 0.0000000000000000000000000000000007897 134.0
WH3_k127_9934222_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 556.0
WH3_k127_9934222_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002863 272.0
WH3_k127_9934222_2 PhzC PhzF - - - 0.00000000000000000000000000000000000000000000000000000000001737 213.0
WH3_k127_9934222_3 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000213 139.0
WH3_k127_9934222_4 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000001017 117.0
WH3_k127_9948745_0 DNA mediated transformation - - - 7.425e-203 653.0
WH3_k127_9948745_1 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 582.0
WH3_k127_9948745_2 of ABC transporters with duplicated ATPase K06158 - - 0.00000000000000000000000000001822 119.0
WH3_k127_9978209_0 Metal-dependent hydrolase - - - 4.318e-260 814.0
WH3_k127_9978209_1 Threonine dehydratase K01754 - 4.3.1.19 5.629e-214 675.0
WH3_k127_9978209_2 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 391.0
WH3_k127_9978209_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000117 100.0
WH3_k127_9978209_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000006437 49.0
WH3_k127_9981498_0 Major Facilitator Superfamily - - - 3.044e-196 620.0
WH3_k127_9981498_1 NADH flavin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 355.0
WH3_k127_9981498_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 351.0
WH3_k127_9981498_3 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 334.0
WH3_k127_9981498_4 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000001586 184.0
WH3_k127_9981498_5 - - - - 0.0000000000000000000000000000000000000000000001587 187.0