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Overview

ID MAG04169
Name WH3_bin.64
Sample SMP0108
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Xanthomonadales
Family Xanthomonadaceae
Genus Thermomonas
Species Thermomonas sp016720345
Assembly information
Completeness (%) 66.45
Contamination (%) 2.23
GC content (%) 70.0
N50 (bp) 4,879
Genome size (bp) 1,682,613

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1857

Gene name Description KEGG GOs EC E-value Score Sequence
WH3_k127_10004993_0 Alkyl hydroperoxide reductase K03387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 526.0
WH3_k127_10004993_1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 491.0
WH3_k127_10004993_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 462.0
WH3_k127_10004993_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002867 256.0
WH3_k127_10004993_4 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000000000004651 125.0
WH3_k127_10041630_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 589.0
WH3_k127_10041630_1 peptidase K07260 - 3.4.17.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 399.0
WH3_k127_10041630_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005607 238.0
WH3_k127_10041630_3 peptidase K07260 - 3.4.17.14 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
WH3_k127_10041630_4 - - - - 0.00000000000000000000000000000000000001625 150.0
WH3_k127_10041630_5 protein conserved in bacteria - - - 0.000000000000000000008923 99.0
WH3_k127_1008812_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 8.875e-294 923.0
WH3_k127_1008812_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 561.0
WH3_k127_1008812_2 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 397.0
WH3_k127_1008812_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 325.0
WH3_k127_1008812_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 289.0
WH3_k127_1008812_5 acetyltransferase K22441 - 2.3.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000001023 259.0
WH3_k127_1008812_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001871 255.0
WH3_k127_10277304_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 449.0
WH3_k127_10277304_1 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 402.0
WH3_k127_10277304_2 Protein of unknown function (DUF1415) K09941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 299.0
WH3_k127_10277304_3 Methyltransferase K00564 - 2.1.1.172 0.000000000000000000000000000000000000000000000000004795 182.0
WH3_k127_10277304_4 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000216 150.0
WH3_k127_10277304_5 - - - - 0.000000000000000000000000000000000000007161 165.0
WH3_k127_1035908_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00632 - 2.3.1.16 2.983e-219 682.0
WH3_k127_1035908_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 503.0
WH3_k127_1035908_2 Multidrug MFS transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 283.0
WH3_k127_10362986_0 Peptidase, M13 K07386 - - 3.621e-318 999.0
WH3_k127_10362986_1 Transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 437.0
WH3_k127_10362986_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 383.0
WH3_k127_10362986_3 Cysteine methyltransferase K07443 - - 0.0000000000000000000000000001444 115.0
WH3_k127_1040613_0 Belongs to the aldehyde dehydrogenase family K00130,K00151,K10217 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0008802,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 1.703e-237 741.0
WH3_k127_1040613_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000006166 65.0
WH3_k127_10408232_0 FAD linked oxidases, C-terminal domain - - - 2.82e-198 631.0
WH3_k127_10408232_1 nitrate reductase K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 354.0
WH3_k127_10408232_2 nitrate reductase K00373 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 316.0
WH3_k127_10408232_3 one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high K00371 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 285.0
WH3_k127_10408232_4 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000238 256.0
WH3_k127_10408232_5 Transporter K02575 - - 0.00000000000003623 74.0
WH3_k127_1041778_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 492.0
WH3_k127_1041778_1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 329.0
WH3_k127_10442256_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 270.0
WH3_k127_10442256_1 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000001981 96.0
WH3_k127_10442256_2 SCP-2 sterol transfer family - - - 0.00004824 51.0
WH3_k127_10443841_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.134e-256 796.0
WH3_k127_10443841_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 511.0
WH3_k127_10443841_2 Belongs to the phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 354.0
WH3_k127_10443841_3 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000002888 124.0
WH3_k127_10472905_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.394e-301 929.0
WH3_k127_10472905_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 6.754e-252 791.0
WH3_k127_10472905_10 - - - - 0.00000000000000000000000000000000000000000001008 168.0
WH3_k127_10472905_12 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000003057 122.0
WH3_k127_10472905_2 Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids K00826 - 2.6.1.42 3.1e-212 662.0
WH3_k127_10472905_3 Histidine kinase - - - 1.2e-202 639.0
WH3_k127_10472905_4 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 517.0
WH3_k127_10472905_5 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 487.0
WH3_k127_10472905_6 esterase K12686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 431.0
WH3_k127_10472905_7 XRE family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 405.0
WH3_k127_10472905_8 Nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003938 278.0
WH3_k127_10472905_9 Putative ATP-dependant zinc protease - - - 0.0000000000000000000000000000000000000000000000000000001506 200.0
WH3_k127_10473583_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 578.0
WH3_k127_10473583_1 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000004564 214.0
WH3_k127_10473583_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000001149 73.0
WH3_k127_1047901_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 458.0
WH3_k127_1047901_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006203 273.0
WH3_k127_1047901_2 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000000000001365 130.0
WH3_k127_1047901_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000003549 49.0
WH3_k127_10549955_0 acyl-coa dehydrogenase - - - 0.0 1041.0
WH3_k127_10549955_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 7.021e-206 663.0
WH3_k127_10549955_2 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 486.0
WH3_k127_10549955_3 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 319.0
WH3_k127_10549955_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001037 270.0
WH3_k127_10549955_5 - - - - 0.000000000000000000000000000000000000000000000000000002969 198.0
WH3_k127_10576194_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1701.0
WH3_k127_10576194_1 receptor K02014 - - 0.0 1460.0
WH3_k127_10576194_2 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 591.0
WH3_k127_10576194_3 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000001629 143.0
WH3_k127_10576194_4 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.0000000000000000000000000000000000277 135.0
WH3_k127_10576194_5 TonB-dependent receptor - - - 0.00000000001685 72.0
WH3_k127_10579540_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 3.16e-322 989.0
WH3_k127_10579540_1 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000000000000000000000000007231 224.0
WH3_k127_10579540_2 CHAD - - - 0.0000000000000000000000000000000000000000006117 173.0
WH3_k127_10579540_3 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000007307 77.0
WH3_k127_10592691_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 535.0
WH3_k127_10592691_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 443.0
WH3_k127_10592691_2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000502 248.0
WH3_k127_10630569_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1654.0
WH3_k127_10630569_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 568.0
WH3_k127_10630569_2 4Fe-4S dicluster domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 420.0
WH3_k127_10630569_3 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 419.0
WH3_k127_10630569_4 DMSO reductase anchor subunit (DmsC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 300.0
WH3_k127_10630569_5 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000000000000006126 177.0
WH3_k127_10630569_6 - - - - 0.000000000000000000000000004581 112.0
WH3_k127_10652103_0 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 415.0
WH3_k127_10652103_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 390.0
WH3_k127_10652103_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 314.0
WH3_k127_10654078_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003882 245.0
WH3_k127_10654078_1 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007552 246.0
WH3_k127_10654078_2 Rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000003259 229.0
WH3_k127_10654078_3 thioesterase - - - 0.0000000000000000000000000000000000000000000000000000215 202.0
WH3_k127_10654078_4 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000006198 168.0
WH3_k127_10690011_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.318e-237 742.0
WH3_k127_10690011_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 455.0
WH3_k127_10690011_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 357.0
WH3_k127_10690011_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000008695 206.0
WH3_k127_10690011_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000001801 123.0
WH3_k127_10729221_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 430.0
WH3_k127_10729221_1 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 334.0
WH3_k127_10729221_2 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000004513 177.0
WH3_k127_10754339_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 597.0
WH3_k127_10754339_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 319.0
WH3_k127_10754339_2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000008553 203.0
WH3_k127_10754339_3 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000003831 196.0
WH3_k127_10754339_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000002353 146.0
WH3_k127_10754339_5 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000482 128.0
WH3_k127_10761008_0 abc transporter atp-binding protein K06147 - - 0.0 1056.0
WH3_k127_10761008_1 Dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 562.0
WH3_k127_10761008_2 ferredoxin--nadp reductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000001047 228.0
WH3_k127_10842763_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 4.904e-272 848.0
WH3_k127_10842763_1 Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001098 259.0
WH3_k127_10842763_2 - - - - 0.0001616 46.0
WH3_k127_10880356_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.254e-269 841.0
WH3_k127_10880356_1 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 5.248e-204 639.0
WH3_k127_10880356_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 565.0
WH3_k127_10880356_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 556.0
WH3_k127_10880356_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 471.0
WH3_k127_10886573_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 1.805e-211 665.0
WH3_k127_10886573_1 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 516.0
WH3_k127_10886573_10 - - - - 0.000000000000000000000000000000000000000002082 158.0
WH3_k127_10886573_11 protein conserved in bacteria - - - 0.0000000000000000000001112 98.0
WH3_k127_10886573_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 466.0
WH3_k127_10886573_3 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 453.0
WH3_k127_10886573_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 408.0
WH3_k127_10886573_5 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001251 274.0
WH3_k127_10886573_6 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001536 241.0
WH3_k127_10886573_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005139 257.0
WH3_k127_10886573_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003459 238.0
WH3_k127_10886573_9 EF-hand domain pair - - - 0.000000000000000000000000000000000000000000000002119 182.0
WH3_k127_10918708_0 Peptidase family M1 domain - - - 1.431e-278 869.0
WH3_k127_10919496_0 General secretion pathway protein K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 8.481e-203 650.0
WH3_k127_10919496_1 General secretion pathway protein K02454 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 479.0
WH3_k127_10919496_2 General secretion pathway protein K02459 - - 0.0000000000000000000000000000000000000000000000000000000000000000001175 243.0
WH3_k127_10919496_3 General secretion pathway protein K02456 - - 0.00000000000000000000000000000000000000000000000000000000000001241 219.0
WH3_k127_10919496_4 General secretion pathway protein K02457 - - 0.000000000000000000000000000000000000000000000002389 186.0
WH3_k127_10919496_5 Prokaryotic N-terminal methylation motif K02458 - - 0.00000000000000000000000000000000000000000008882 173.0
WH3_k127_10919496_6 Type II secretion system protein K K02460 - - 0.000000000000000000000000001158 126.0
WH3_k127_10922000_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1022.0
WH3_k127_10922000_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 602.0
WH3_k127_10922000_2 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 556.0
WH3_k127_10922000_3 von willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004753 263.0
WH3_k127_10924332_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.117e-260 812.0
WH3_k127_10924332_1 overlaps another CDS with the same product name K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 581.0
WH3_k127_10924332_2 permease K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 543.0
WH3_k127_10924332_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 426.0
WH3_k127_10924332_4 Tyrosine recombinase xerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 435.0
WH3_k127_10924332_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 379.0
WH3_k127_10924332_6 dna polymerase III K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000005499 244.0
WH3_k127_10924332_7 membrane protein domain - - - 0.00000000000000000000000000000000000000000000000000002827 209.0
WH3_k127_10924332_8 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.000000006939 58.0
WH3_k127_10935297_0 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 571.0
WH3_k127_10935297_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 557.0
WH3_k127_10935297_2 porphyrin biosynthesis protein K02498 - - 0.000000000000000000000005309 102.0
WH3_k127_1094574_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 374.0
WH3_k127_1094574_1 amino acid K03294,K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 330.0
WH3_k127_1094574_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006116 263.0
WH3_k127_1094574_3 - - - - 0.000000000000000000000000000000000000000000000002574 178.0
WH3_k127_10956384_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0 1010.0
WH3_k127_10956384_1 ABC transporter substrate-binding protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 455.0
WH3_k127_10956384_2 abc transporter atp-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 440.0
WH3_k127_10956384_3 transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 369.0
WH3_k127_10956384_4 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000000000000000000000000000000001404 235.0
WH3_k127_10956384_5 abc transporter, permease K02066 - - 0.0000000000000000001051 88.0
WH3_k127_10979451_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1159.0
WH3_k127_10979451_1 Protein of unknown function (DUF808) K09781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 491.0
WH3_k127_10979451_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 299.0
WH3_k127_10989314_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 574.0
WH3_k127_10989314_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000003123 262.0
WH3_k127_10989314_2 converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000004132 237.0
WH3_k127_10989314_3 AsnC-type helix-turn-helix domain K03719 - - 0.000000000000000000000000000000000000000000000000000000000000002345 221.0
WH3_k127_11023656_0 Transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 479.0
WH3_k127_11023656_1 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 412.0
WH3_k127_11023656_2 membrane protein (homolog of Drosophila rhomboid) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 334.0
WH3_k127_11023656_3 acetyltransferase K06975 - - 0.0000000000000000000000000005813 115.0
WH3_k127_11023656_4 Cold-shock protein K03704 - - 0.0000000000008296 67.0
WH3_k127_1103228_0 CHASE2 domain protein - - - 5.925e-217 689.0
WH3_k127_1103228_1 Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD K03592 - - 4.618e-214 671.0
WH3_k127_1103228_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 409.0
WH3_k127_1103228_3 Domain of unknown function (DUF4870) K09940 - - 0.00000000000000000000000000000000000000000000000000000001929 217.0
WH3_k127_1103228_4 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000001484 193.0
WH3_k127_1103228_5 Domain of unknown function (DUF4870) - - - 0.0000000000000000000000000000000002012 139.0
WH3_k127_11058650_0 Acetylglutamate kinase K22478 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 1.925e-260 811.0
WH3_k127_11058650_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.755e-243 755.0
WH3_k127_11058650_2 Acetylornithine deacetylase K01438 - 3.5.1.16 3.442e-197 619.0
WH3_k127_11058650_3 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 567.0
WH3_k127_11058650_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000003068 153.0
WH3_k127_11091417_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 1.064e-312 972.0
WH3_k127_11091417_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 579.0
WH3_k127_11091417_2 Belongs to the bacterial glucokinase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 529.0
WH3_k127_11091417_3 6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000001051 233.0
WH3_k127_11091417_4 Aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000008372 108.0
WH3_k127_11104188_0 protein conserved in bacteria - - - 4.901e-217 684.0
WH3_k127_11104188_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 430.0
WH3_k127_11104188_2 Catalyzes the sodium-dependent transport of glutamate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 308.0
WH3_k127_11107868_0 membrane - - - 0.0 1187.0
WH3_k127_11107868_1 Involved in the processing of the 5'end of 16S rRNA K08301 - - 2.156e-278 872.0
WH3_k127_11107868_2 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 317.0
WH3_k127_11107868_3 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 286.0
WH3_k127_11186394_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 2.416e-289 892.0
WH3_k127_11188983_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1011.0
WH3_k127_11188983_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 421.0
WH3_k127_11188983_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 319.0
WH3_k127_11188983_3 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000009871 258.0
WH3_k127_11188983_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000001059 146.0
WH3_k127_11188983_5 Concanavalin A-like lectin/glucanases superfamily - - - 0.000002515 51.0
WH3_k127_11227296_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1831.0
WH3_k127_11227296_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 6.14e-233 730.0
WH3_k127_11293342_0 M61 glycyl aminopeptidase - - - 0.0 1199.0
WH3_k127_11293342_1 Major facilitator superfamily K08151 - - 4.343e-212 664.0
WH3_k127_11293342_2 Uncharacterized protein conserved in bacteria (DUF2239) K09965 - - 0.00000000000000000000000000000000000005663 144.0
WH3_k127_1129406_0 aminotransferase K14287 - 2.6.1.88 5.501e-209 654.0
WH3_k127_1129406_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 454.0
WH3_k127_1129406_2 carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 443.0
WH3_k127_1129406_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 420.0
WH3_k127_1129406_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 359.0
WH3_k127_1129406_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 346.0
WH3_k127_1129406_6 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000356 168.0
WH3_k127_11311898_0 protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 494.0
WH3_k127_11311898_1 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 321.0
WH3_k127_11406110_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1037.0
WH3_k127_11406110_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 582.0
WH3_k127_11406110_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 389.0
WH3_k127_11406110_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000004681 188.0
WH3_k127_11406110_4 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000000001024 83.0
WH3_k127_11406110_5 - K08992 - - 0.000000000000001517 79.0
WH3_k127_11445754_0 Mitochondrial fission ELM1 K07276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 423.0
WH3_k127_11445754_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 394.0
WH3_k127_11445754_2 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 338.0
WH3_k127_11445754_3 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 283.0
WH3_k127_11445754_4 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000005488 244.0
WH3_k127_11445754_5 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001899 243.0
WH3_k127_11445754_6 protein conserved in bacteria - - - 0.00000000000000000000006143 100.0
WH3_k127_11476514_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 2.954e-197 626.0
WH3_k127_11476514_1 protein conserved in bacteria containing a pentein-type domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 479.0
WH3_k127_11476514_2 aconitate hydratase K20455 - 4.2.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 289.0
WH3_k127_11476514_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 - - 0.00000000000000000000000000000000000005991 143.0
WH3_k127_11476514_4 - - - - 0.00000000000000000000009373 106.0
WH3_k127_11478081_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 463.0
WH3_k127_11478081_1 peptidase K01354 - 3.4.21.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 394.0
WH3_k127_11478081_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 391.0
WH3_k127_11478081_3 protein conserved in bacteria K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 366.0
WH3_k127_11478081_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 340.0
WH3_k127_11478081_5 membrane K09790 - - 0.000000000000000000000000000000000000000000000000001826 184.0
WH3_k127_11478081_6 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000003595 193.0
WH3_k127_11478081_7 - - - - 0.0000000000002702 82.0
WH3_k127_11521134_0 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 1.401e-301 927.0
WH3_k127_11521134_1 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004589 268.0
WH3_k127_11521134_2 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000003236 177.0
WH3_k127_11521134_3 - - - - 0.00000000000000000000000000000000000000002821 164.0
WH3_k127_11521134_4 - - - - 0.0000000000000000000000000000000000003617 159.0
WH3_k127_11521134_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001595 100.0
WH3_k127_11521134_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000001267 93.0
WH3_k127_11529153_0 LssY C-terminus - - - 4.301e-285 897.0
WH3_k127_11529153_1 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 7.369e-248 784.0
WH3_k127_11529153_10 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000000000000000000002356 234.0
WH3_k127_11529153_11 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000211 230.0
WH3_k127_11529153_12 Domain of Unknown Function (DUF350) K08989 - - 0.000000000000000000000000000009013 123.0
WH3_k127_11529153_13 rubredoxin - - - 0.0000000000000000000000000002428 121.0
WH3_k127_11529153_2 also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 2.116e-203 656.0
WH3_k127_11529153_3 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 7.105e-198 624.0
WH3_k127_11529153_4 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 527.0
WH3_k127_11529153_5 dehydrogenase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 481.0
WH3_k127_11529153_6 Ion transporter K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 451.0
WH3_k127_11529153_7 Glutathionylspermidine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 424.0
WH3_k127_11529153_8 Glyoxalase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000004868 259.0
WH3_k127_11529153_9 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000000000000000000000000000000000000009042 238.0
WH3_k127_11540081_0 Peptidase S46 - - - 4.849e-309 951.0
WH3_k127_11540081_1 Dipeptidyl-peptidase 7 - - - 1.642e-200 638.0
WH3_k127_11609645_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 1.824e-263 818.0
WH3_k127_11609645_1 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 316.0
WH3_k127_11609645_2 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001793 264.0
WH3_k127_11609645_3 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.00000000000000000000000000000002357 130.0
WH3_k127_11613299_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1065.0
WH3_k127_11613299_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 591.0
WH3_k127_11613299_2 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 307.0
WH3_k127_11634638_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 562.0
WH3_k127_11634638_1 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004138 258.0
WH3_k127_11634638_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000008078 228.0
WH3_k127_11634638_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000001305 71.0
WH3_k127_1168141_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 548.0
WH3_k127_1168141_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 445.0
WH3_k127_1168141_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000008514 226.0
WH3_k127_1168141_3 Tfp pilus assembly protein FimV K08086 - - 0.000000000002701 67.0
WH3_k127_11703954_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 472.0
WH3_k127_11703954_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 349.0
WH3_k127_11703954_2 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.000000000000000000000000000000000000000000000000002316 183.0
WH3_k127_11712609_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 2.857e-244 775.0
WH3_k127_11712609_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 510.0
WH3_k127_11712609_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 413.0
WH3_k127_11712609_3 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 338.0
WH3_k127_11712609_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 312.0
WH3_k127_11712609_5 Protein of unknown function (DUF3144) - - - 0.00000000000000000000000000000000000000000000369 172.0
WH3_k127_11717294_0 UPF0056 membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 308.0
WH3_k127_11717294_1 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002113 252.0
WH3_k127_11717294_2 Oar protein - - - 0.0000000000000000000000000000000000000000000000000000003376 198.0
WH3_k127_11729136_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 3.916e-246 769.0
WH3_k127_11729136_1 Sulfate adenylyltransferase subunit 2 K00957 - 2.7.7.4 0.00000000000000000000000000001701 117.0
WH3_k127_11787964_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 8.599e-262 808.0
WH3_k127_11787964_1 stringent starvation protein A K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 393.0
WH3_k127_11787964_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 351.0
WH3_k127_11787964_3 cytochrome K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 343.0
WH3_k127_11787964_4 stringent starvation protein b K03600 - - 0.0000000000000000000000000000000000000000000000000000001152 198.0
WH3_k127_11791401_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 573.0
WH3_k127_11791401_1 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K00104 - 1.1.2.3,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 456.0
WH3_k127_11791401_2 - - - - 0.00000271 59.0
WH3_k127_11898255_0 Belongs to the agmatine deiminase family - - - 2.367e-211 660.0
WH3_k127_11898255_1 Acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 479.0
WH3_k127_11898255_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008786 381.0
WH3_k127_11898255_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 369.0
WH3_k127_11898255_4 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000000009085 84.0
WH3_k127_11905926_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 8.579e-239 755.0
WH3_k127_11905926_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 421.0
WH3_k127_11973613_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 416.0
WH3_k127_11973613_1 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 313.0
WH3_k127_11973613_2 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000000000000000000403 112.0
WH3_k127_12034931_0 CHAT domain - - - 0.0 1098.0
WH3_k127_12034931_1 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 8.481e-260 814.0
WH3_k127_12034931_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 588.0
WH3_k127_12034931_3 haemagglutination activity domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 490.0
WH3_k127_12037181_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1192.0
WH3_k127_12037181_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1013.0
WH3_k127_12037181_10 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 413.0
WH3_k127_12037181_11 Acetolactate synthase K11258 - 2.2.1.6 0.000000000000000000000000000005357 126.0
WH3_k127_12037181_12 - - - - 0.000000000001605 80.0
WH3_k127_12037181_2 Acetolactate synthase K01652 - 2.2.1.6 4.405e-310 969.0
WH3_k127_12037181_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - - 3.022e-297 955.0
WH3_k127_12037181_4 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.933e-274 864.0
WH3_k127_12037181_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.564e-267 848.0
WH3_k127_12037181_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.24e-234 750.0
WH3_k127_12037181_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 601.0
WH3_k127_12037181_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 584.0
WH3_k127_12037181_9 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 519.0
WH3_k127_12076229_0 membrane - - - 9.201e-202 636.0
WH3_k127_12076229_1 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 559.0
WH3_k127_12076229_2 transport protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 558.0
WH3_k127_12076229_3 Transporter K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 488.0
WH3_k127_12076229_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 293.0
WH3_k127_12076229_5 peptidase - - - 0.0000000000000000000000000000000000000000000000000000001315 194.0
WH3_k127_12076229_6 Phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000002486 69.0
WH3_k127_12092505_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 302.0
WH3_k127_12092505_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 301.0
WH3_k127_12092505_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 298.0
WH3_k127_12092505_3 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004362 254.0
WH3_k127_12092505_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000003543 224.0
WH3_k127_12092505_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000003899 201.0
WH3_k127_12092505_6 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000001477 101.0
WH3_k127_12104674_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.485e-248 771.0
WH3_k127_12104674_1 component I K01657 - 4.1.3.27 5.104e-208 661.0
WH3_k127_12104674_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 516.0
WH3_k127_12104674_3 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 426.0
WH3_k127_12104674_4 Amino-transferase class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 389.0
WH3_k127_12104674_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 357.0
WH3_k127_12104674_6 the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 344.0
WH3_k127_12104674_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 341.0
WH3_k127_12104674_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000002103 144.0
WH3_k127_12112360_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 5.251e-312 961.0
WH3_k127_12112360_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 534.0
WH3_k127_12112360_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 460.0
WH3_k127_12112360_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 349.0
WH3_k127_12112360_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 363.0
WH3_k127_12112360_5 endonuclease containing a URI domain K07461 - - 0.000000000000000000000000000000000000000236 152.0
WH3_k127_1213362_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.796e-300 925.0
WH3_k127_1213362_1 endonuclease containing a URI domain K07461 - - 0.000000000000000000000000002319 113.0
WH3_k127_1214209_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.0 1135.0
WH3_k127_12156633_0 type VI secretion protein K11893 - - 2.329e-271 844.0
WH3_k127_12156633_1 TraB family K00657,K09973 - 2.3.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 386.0
WH3_k127_12177192_0 glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 424.0
WH3_k127_12177192_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 384.0
WH3_k127_12177192_2 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000005391 203.0
WH3_k127_12220870_0 Protein tyrosine kinase K12132 - 2.7.11.1 1.282e-292 910.0
WH3_k127_12220870_1 desaturase K00507 - 1.14.19.1 2.859e-231 720.0
WH3_k127_12220870_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 476.0
WH3_k127_12220870_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 325.0
WH3_k127_12220870_4 Thioredoxin-like - - - 0.00000000000000000000000000000000000000006458 157.0
WH3_k127_12246391_0 Small-conductance mechanosensitive channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 582.0
WH3_k127_12246391_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 317.0
WH3_k127_12246391_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000002188 229.0
WH3_k127_12246391_3 phenol hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000005029 202.0
WH3_k127_12246391_4 - - - - 0.000000000000000000000000000000000000000000005443 169.0
WH3_k127_12246391_6 Helix-turn-helix domain K07729 - - 0.0008282 42.0
WH3_k127_12249341_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.714e-205 653.0
WH3_k127_12249341_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 533.0
WH3_k127_12249341_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 497.0
WH3_k127_12341837_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0 1023.0
WH3_k127_12341837_1 7TMR-DISM extracellular 2 - - - 1.508e-262 821.0
WH3_k127_12341837_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 2.299e-245 764.0
WH3_k127_12341837_3 type VI secretion protein K11900 - - 1.902e-235 728.0
WH3_k127_12341837_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 597.0
WH3_k127_12341837_5 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 429.0
WH3_k127_12341837_6 type VI secretion protein K11897 - - 0.00000000000000000000000000000000000000000000000000000000000000008954 224.0
WH3_k127_12341837_7 calcineurin phosphoesterase - - - 0.000000000000000000000000000000000000002592 150.0
WH3_k127_12341837_8 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000000008253 147.0
WH3_k127_12410275_0 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 415.0
WH3_k127_12410275_1 RNA polymerase sigma factor RpoH K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 325.0
WH3_k127_12410275_2 response regulator - - - 0.00000000000000000000000000000000000000000006072 161.0
WH3_k127_12427195_0 MacB-like periplasmic core domain K02004 - - 4.281e-225 703.0
WH3_k127_12427195_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 2.62e-218 680.0
WH3_k127_12427195_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 447.0
WH3_k127_12427195_3 EamA-like transporter family K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 415.0
WH3_k127_12427195_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 380.0
WH3_k127_12427195_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000001429 165.0
WH3_k127_12431672_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 3.724e-212 662.0
WH3_k127_12431672_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000003509 149.0
WH3_k127_12440577_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 7.921e-214 669.0
WH3_k127_12440577_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 336.0
WH3_k127_12461008_0 receptor K16090 - - 0.0 1027.0
WH3_k127_12461008_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 5.344e-215 682.0
WH3_k127_12461008_2 abc transporter, permease K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 545.0
WH3_k127_12461008_3 Part of SUF system involved in inserting iron-sulfur clusters into proteins K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 455.0
WH3_k127_12461008_4 Putative PepSY_TM-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 313.0
WH3_k127_12461008_5 HutD K09975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004282 282.0
WH3_k127_12461008_6 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003499 271.0
WH3_k127_12461008_7 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.0000000000000000000000000000000000000000000000000003071 188.0
WH3_k127_12461008_8 Cysteine desulfurase activator complex subunit SufB K09014 - - 0.000000000000000000000000000000000000000000000001356 173.0
WH3_k127_12461008_9 competence protein ComEA K02237 - - 0.0000000000000000000000000000000000004422 143.0
WH3_k127_12468794_0 Phage late control gene D protein (GPD) K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008807 446.0
WH3_k127_12468794_1 Domain of unknown function (DUF4123) - - - 0.0000000000000000000000000000000000000000000000000000000000000003647 226.0
WH3_k127_12468794_2 COG0542 ATPases with chaperone activity, ATP-binding subunit K11907 - - 0.000000000000000000000000000000000000000000000000000001424 192.0
WH3_k127_12477861_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 484.0
WH3_k127_12477861_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 451.0
WH3_k127_12477861_2 esterase K12686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 452.0
WH3_k127_12477861_3 Potassium transporter TrkA - - - 0.0000000000000000000000000000000000000000001759 160.0
WH3_k127_12477861_4 Thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000000000003252 98.0
WH3_k127_12496774_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.141e-319 983.0
WH3_k127_12496774_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000002747 158.0
WH3_k127_12496774_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.00000000000000002475 83.0
WH3_k127_12531641_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 327.0
WH3_k127_12531641_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000004978 243.0
WH3_k127_12531641_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000001466 253.0
WH3_k127_12531641_3 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.0000000000000000000000000000004809 122.0
WH3_k127_12546060_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 4.906e-263 812.0
WH3_k127_12546060_1 Beta-eliminating lyase K01667 - 4.1.99.1 5.903e-231 722.0
WH3_k127_12546060_2 hemolysin III K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 361.0
WH3_k127_12546060_3 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000007841 189.0
WH3_k127_12556988_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 345.0
WH3_k127_12556988_1 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 300.0
WH3_k127_12556988_2 polyketide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000001521 248.0
WH3_k127_12556988_3 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.00000000000000000000000000000000000000002725 155.0
WH3_k127_12556988_4 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000004617 145.0
WH3_k127_12560864_0 Nitrite reductase K15864 - 1.7.2.1,1.7.99.1 0.0 1024.0
WH3_k127_12560864_1 receptor K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 597.0
WH3_k127_12560864_2 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 383.0
WH3_k127_12560864_3 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 350.0
WH3_k127_12560864_4 Catalyzes the cleavage of L-fuculose 1-phosphate to glycerone phosphate and L-lactaldehyde K01628,K22130 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008270,GO:0008738,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0043167,GO:0043169,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046372,GO:0046872,GO:0046914,GO:0071704,GO:1901575 4.1.1.104,4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 343.0
WH3_k127_12560864_5 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 312.0
WH3_k127_12560864_6 calcineurin phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000001506 228.0
WH3_k127_12582920_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.119e-316 974.0
WH3_k127_12582920_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000007862 179.0
WH3_k127_12590124_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 5.371e-221 692.0
WH3_k127_12590124_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 438.0
WH3_k127_12590124_2 Glycine cleavage system regulatory protein K03567 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 355.0
WH3_k127_12590124_3 Peroxiredoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000755 267.0
WH3_k127_12590124_4 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000000001045 222.0
WH3_k127_12590124_5 Gram-negative-bacterium-type cell outer membrane assembly - - - 0.00000000000000000000000000000000000000000000000000000000000002794 218.0
WH3_k127_12613994_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 544.0
WH3_k127_12613994_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 475.0
WH3_k127_12613994_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000651 291.0
WH3_k127_12613994_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000005947 211.0
WH3_k127_12663490_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 425.0
WH3_k127_12663490_1 regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 400.0
WH3_k127_12674531_0 dna polymerase K02337 - 2.7.7.7 1.876e-199 627.0
WH3_k127_12674531_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 469.0
WH3_k127_12674531_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001351 274.0
WH3_k127_12699526_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 468.0
WH3_k127_12699526_1 Belongs to the pseudouridine synthase RsuA family K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 294.0
WH3_k127_12709606_0 (Lipo)protein K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 483.0
WH3_k127_12709606_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 411.0
WH3_k127_12709606_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 284.0
WH3_k127_12709606_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001563 271.0
WH3_k127_12709606_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000008688 255.0
WH3_k127_12709606_5 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000000000000000000000000001979 197.0
WH3_k127_12709606_6 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000001466 200.0
WH3_k127_12713080_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 473.0
WH3_k127_12713080_1 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 350.0
WH3_k127_12782618_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 6.281e-248 769.0
WH3_k127_12782618_1 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 1.691e-241 752.0
WH3_k127_12782618_2 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase K03392 - 4.1.1.45 1.081e-218 683.0
WH3_k127_12782618_3 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates K01141 - 3.1.11.1 3.787e-217 681.0
WH3_k127_12782618_4 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 280.0
WH3_k127_12814090_0 signal peptide peptidase K04773 - - 1.739e-260 812.0
WH3_k127_12814090_1 Multidrug efflux pump K03327 GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 330.0
WH3_k127_12863870_0 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 356.0
WH3_k127_12863870_1 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000118 181.0
WH3_k127_12863870_2 Predicted integral membrane protein (DUF2282) - - - 0.0000000000000000000000000000000002025 136.0
WH3_k127_12916024_0 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease K03694 - - 3.087e-262 813.0
WH3_k127_12916024_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 9.551e-201 635.0
WH3_k127_12916024_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 610.0
WH3_k127_12916024_3 High frequency lysogenization protein HflD homolog K07153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 293.0
WH3_k127_12916024_4 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003874 271.0
WH3_k127_12916024_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000000000008662 194.0
WH3_k127_12916024_6 Outer membrane efflux protein - - - 0.000000000000000000003226 109.0
WH3_k127_12920382_0 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 9.538e-251 785.0
WH3_k127_12920382_1 Histidine kinase K07636 - 2.7.13.3 3.413e-220 689.0
WH3_k127_12920382_10 - - - - 0.0000002563 53.0
WH3_k127_12920382_13 - - - - 0.00002189 53.0
WH3_k127_12920382_14 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00009158 55.0
WH3_k127_12920382_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 3.528e-219 690.0
WH3_k127_12920382_3 Catalyzes the formation of 2-oxoglutarate from isocitrate K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 606.0
WH3_k127_12920382_4 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 443.0
WH3_k127_12920382_5 Two component response regulator for the phosphate regulon K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 426.0
WH3_k127_12920382_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 382.0
WH3_k127_12920382_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002899 245.0
WH3_k127_12920382_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000000000002286 158.0
WH3_k127_12920382_9 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000002079 72.0
WH3_k127_12930622_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 2.617e-216 676.0
WH3_k127_12930622_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 482.0
WH3_k127_12930622_2 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 359.0
WH3_k127_12945508_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.364e-286 894.0
WH3_k127_12945508_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 2.307e-210 662.0
WH3_k127_12945508_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 569.0
WH3_k127_12945508_3 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 472.0
WH3_k127_12945508_4 abc transporter atp-binding protein K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 426.0
WH3_k127_12945508_5 PTS system fructose IIA component family protein K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000000000000000000000002812 218.0
WH3_k127_12945508_6 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.000000000000000000000000000000000000000000000000002169 190.0
WH3_k127_12945508_7 modulation protein K05808 - - 0.00000000000000000000000000000000000000000000004701 171.0
WH3_k127_12945508_8 phosphocarrier protein HPr K11189 - - 0.00000000000000000000000000000000000000007381 152.0
WH3_k127_12945508_9 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.000000000000201 70.0
WH3_k127_12964300_0 May be involved in recombinational repair of damaged DNA K03631 - - 2.221e-244 769.0
WH3_k127_12964300_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 561.0
WH3_k127_12964300_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 287.0
WH3_k127_12964300_3 Oligoketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001407 251.0
WH3_k127_12964300_4 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000003566 231.0
WH3_k127_12964300_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000004175 216.0
WH3_k127_12964300_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000000000000000000000002169 183.0
WH3_k127_12964300_7 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000008459 109.0
WH3_k127_12984864_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 5.79e-252 788.0
WH3_k127_12984864_1 Zinc metalloprotease (Elastase) K01399,K08604 - 3.4.24.25,3.4.24.26 3.652e-224 705.0
WH3_k127_12984864_2 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 418.0
WH3_k127_12984864_3 FeS assembly SUF system protein SufT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 317.0
WH3_k127_12984864_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003902 277.0
WH3_k127_12984864_5 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000004711 175.0
WH3_k127_12984864_6 Protein of unknown function (DUF3106) - - - 0.0000000000000000000000000000000000000002571 153.0
WH3_k127_12984864_7 - - - - 0.0000000000000000000000000001825 120.0
WH3_k127_12984864_8 - - - - 0.00000000004878 73.0
WH3_k127_1301372_0 Transporter K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 558.0
WH3_k127_1301372_1 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 333.0
WH3_k127_1301372_2 MarR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000009401 217.0
WH3_k127_13017438_0 amidohydrolase - - - 5.434e-270 839.0
WH3_k127_13017438_1 Amidohydrolase family - - - 2.603e-220 690.0
WH3_k127_13017438_2 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 3.123e-199 621.0
WH3_k127_13017438_3 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile K01241 - 3.2.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 494.0
WH3_k127_13017438_4 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 490.0
WH3_k127_13017438_5 lipid binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 466.0
WH3_k127_13017438_6 Von willebrand factor, type a - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003426 273.0
WH3_k127_13017438_7 Protein of unknown function (DUF1761) - - - 0.000000000000000000000000000000000000000000000000000002699 194.0
WH3_k127_13017438_8 - - - - 0.000000000000000000000000000000000000000006581 158.0
WH3_k127_13020652_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 3.662e-267 831.0
WH3_k127_13020652_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 597.0
WH3_k127_13020652_2 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 405.0
WH3_k127_13020652_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 400.0
WH3_k127_13020652_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006878 239.0
WH3_k127_13020652_5 Protein of unknown function (DUF3011) - - - 0.0000000000000000000000000000000000002999 147.0
WH3_k127_13020652_6 RDD family - - - 0.000000000000000000000000000000009724 137.0
WH3_k127_13020652_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000004629 117.0
WH3_k127_13020652_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000003924 104.0
WH3_k127_13020652_9 EF hand - - - 0.000006552 54.0
WH3_k127_1302583_0 Sodium:sulfate symporter transmembrane region - - - 2.152e-310 961.0
WH3_k127_1302583_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 9.943e-221 693.0
WH3_k127_1302583_2 Belongs to the FBPase class 1 family K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000001206 79.0
WH3_k127_13027070_0 peptidylprolyl K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 346.0
WH3_k127_13027070_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004064 278.0
WH3_k127_13027070_2 GntR family transcriptional regulator K07979 - - 0.0000000000000001651 78.0
WH3_k127_13027070_4 peptidylprolyl K03772 - 5.2.1.8 0.0001178 46.0
WH3_k127_13047_0 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 4.197e-260 829.0
WH3_k127_13047_1 Ammonium transporter K03320 - - 1.033e-231 727.0
WH3_k127_13047_2 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 582.0
WH3_k127_13047_3 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001971 216.0
WH3_k127_13047_4 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000954 192.0
WH3_k127_13047_5 cheY-homologous receiver domain - - - 0.00000000000000000000005888 109.0
WH3_k127_13047_6 Bacterial protein of unknown function (Gcw_chp) - - - 0.00001483 47.0
WH3_k127_13069285_0 3HB-oligomer hydrolase (3HBOH) K07518 - 3.1.1.22 1.298e-200 640.0
WH3_k127_13069285_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 471.0
WH3_k127_13069285_2 LuxR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 393.0
WH3_k127_13069285_3 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
WH3_k127_13069285_4 protein conserved in bacteria K09912 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001134 258.0
WH3_k127_13069285_5 COG0591 Na proline symporter - - - 0.000000000000000000000000000000000000000004713 156.0
WH3_k127_13101920_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.106e-304 942.0
WH3_k127_13101920_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000003431 79.0
WH3_k127_13102152_0 2-keto-4-pentenoate hydratase K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 587.0
WH3_k127_13102152_1 maleylacetoacetate isomerase K01800 - 5.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 384.0
WH3_k127_13102152_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 383.0
WH3_k127_13102152_3 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001028 249.0
WH3_k127_13102152_4 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000003525 243.0
WH3_k127_13102152_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002961 173.0
WH3_k127_13104847_0 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA K06445 - - 0.0 1466.0
WH3_k127_13104847_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1103.0
WH3_k127_13104847_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 331.0
WH3_k127_13119618_0 Belongs to the UbiD family - - - 4.463e-212 672.0
WH3_k127_13119618_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000001649 151.0
WH3_k127_13138467_0 Glycosyl transferase - - - 2.617e-248 778.0
WH3_k127_13201854_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0 1071.0
WH3_k127_13201854_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 3.199e-242 768.0
WH3_k127_13201854_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 387.0
WH3_k127_13201854_3 Biopolymer K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 366.0
WH3_k127_13201854_4 Lipoprotein releasing system transmembrane protein K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007732 271.0
WH3_k127_13201854_5 Biopolymer K03559 - - 0.0000000000000000000000000000000000000000000000000000000000001068 215.0
WH3_k127_13201854_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000001007 185.0
WH3_k127_13295378_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 9.645e-224 709.0
WH3_k127_13295378_1 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000000000000005498 165.0
WH3_k127_13295378_2 Protein of unknown function (DUF2782) - - - 0.000000000000000000000006814 117.0
WH3_k127_13323550_0 peptidase - - - 1.336e-296 915.0
WH3_k127_13323550_1 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 565.0
WH3_k127_13323550_2 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 408.0
WH3_k127_13323550_3 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006566 323.0
WH3_k127_13323550_4 Inner membrane protein CreD K06143 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 310.0
WH3_k127_13323550_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005391 259.0
WH3_k127_13323550_6 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000002563 271.0
WH3_k127_13323550_7 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000008129 224.0
WH3_k127_13323550_8 Inner membrane protein CreD K06143 - - 0.0000000000000000002728 97.0
WH3_k127_13389573_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 598.0
WH3_k127_13389573_1 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 583.0
WH3_k127_13389573_2 ABC-type spermidine putrescine transport system, permease component I K11075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 511.0
WH3_k127_13389573_3 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 400.0
WH3_k127_13389573_4 Spermidine putrescine ABC transporter permease K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 408.0
WH3_k127_13389573_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 374.0
WH3_k127_13389573_6 endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 364.0
WH3_k127_13389573_7 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 315.0
WH3_k127_13389573_8 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000003397 218.0
WH3_k127_13389573_9 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000002843 179.0
WH3_k127_13395363_0 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 457.0
WH3_k127_13395363_1 acetyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 350.0
WH3_k127_13395363_2 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 325.0
WH3_k127_13395363_3 phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 327.0
WH3_k127_13395363_4 Cardiolipin synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 300.0
WH3_k127_13395363_5 Domain of unknown function (DUF4377) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 291.0
WH3_k127_13395363_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000122 121.0
WH3_k127_13425576_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 1.19e-221 688.0
WH3_k127_13425576_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 571.0
WH3_k127_13425576_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 436.0
WH3_k127_13425576_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 422.0
WH3_k127_13425576_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 347.0
WH3_k127_13425576_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001403 267.0
WH3_k127_13425576_6 PFAM Acyltransferase - - - 0.000000000000000000000000249 108.0
WH3_k127_13460595_0 NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate K00031 - 1.1.1.42 8.397e-248 767.0
WH3_k127_13460595_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 324.0
WH3_k127_13460595_2 Belongs to the pseudouridine synthase RsuA family K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 0.00000000000000000000007564 99.0
WH3_k127_1346798_0 transporter - - - 0.0 1010.0
WH3_k127_1346798_1 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 592.0
WH3_k127_1346798_2 Transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000246 195.0
WH3_k127_13493908_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 4.038e-277 856.0
WH3_k127_13493908_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 291.0
WH3_k127_13493908_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 294.0
WH3_k127_13493908_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000005231 244.0
WH3_k127_13588976_0 type VI secretion protein K11891 - - 4.789e-311 1004.0
WH3_k127_13588976_2 Type VI secretion system protein DotU K11892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 501.0
WH3_k127_13588976_3 ImpA, N-terminal, type VI secretion system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 406.0
WH3_k127_13594815_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 8.698e-225 704.0
WH3_k127_13594815_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.206e-194 612.0
WH3_k127_13594815_2 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 525.0
WH3_k127_13594815_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 289.0
WH3_k127_13594815_4 abc transporter atp-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004056 274.0
WH3_k127_13594815_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000336 239.0
WH3_k127_13633713_0 Male sterility protein - - - 9.221e-304 934.0
WH3_k127_13747044_0 transport system involved in gliding motility, auxiliary component - - - 1.012e-226 714.0
WH3_k127_13747044_1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004779 258.0
WH3_k127_13790826_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 7.76e-255 791.0
WH3_k127_13790826_1 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 1.627e-247 769.0
WH3_k127_13790826_2 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 396.0
WH3_k127_13790826_3 peptidylprolyl K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 351.0
WH3_k127_13790826_4 peptidylprolyl K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 342.0
WH3_k127_13790826_5 Nucleoprotein polynucleotide-associated enzyme K09912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004834 274.0
WH3_k127_13790826_6 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000004925 267.0
WH3_k127_13790826_7 GntR family transcriptional regulator K07979 - - 0.00000000000000000000000000000000000000000211 155.0
WH3_k127_13790826_8 SlyX K03745 - - 0.0000000000000000000000005695 120.0
WH3_k127_1413982_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 542.0
WH3_k127_1413982_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000855 271.0
WH3_k127_1530247_0 type VI secretion protein K11896 - - 0.0 1043.0
WH3_k127_1530247_1 Type VI secretion K11895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 334.0
WH3_k127_1556097_0 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 3.256e-258 803.0
WH3_k127_1556097_1 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 442.0
WH3_k127_1556097_2 carbonic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 319.0
WH3_k127_1556097_3 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000000000000000000004548 148.0
WH3_k127_1615184_0 lysine biosynthetic process via aminoadipic acid - - - 0.0 1155.0
WH3_k127_1615184_1 aminopeptidase - - - 0.0 1013.0
WH3_k127_1615184_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 501.0
WH3_k127_1615184_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 371.0
WH3_k127_1615184_4 Sugar kinase K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 296.0
WH3_k127_1615184_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 280.0
WH3_k127_1641560_0 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 - - 0.0 1291.0
WH3_k127_1641560_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 3.273e-243 754.0
WH3_k127_1641560_10 - - - - 0.000000000000000007538 86.0
WH3_k127_1641560_11 - - - - 0.0000000000000000418 85.0
WH3_k127_1641560_2 Recombination factor protein RarA K07478 - - 1.821e-225 705.0
WH3_k127_1641560_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 433.0
WH3_k127_1641560_4 exonuclease K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 330.0
WH3_k127_1641560_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 297.0
WH3_k127_1641560_6 protein conserved in bacteria K09920 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004346 269.0
WH3_k127_1641560_7 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 265.0
WH3_k127_1641560_8 Cell division protein ftsk K03466 - - 0.0000000000000000000000000000000000000000000000000000000000001061 213.0
WH3_k127_1641560_9 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000000000000000002819 205.0
WH3_k127_1688744_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 511.0
WH3_k127_1688744_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 287.0
WH3_k127_1690877_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 9.969e-197 614.0
WH3_k127_1690877_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 499.0
WH3_k127_1690877_2 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 467.0
WH3_k127_1690877_3 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 394.0
WH3_k127_1690877_4 - - - - 0.000000000000000000000000000000000000000000000002826 173.0
WH3_k127_1690877_5 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.00000000008467 70.0
WH3_k127_1697119_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000003362 206.0
WH3_k127_1697119_1 Type II secretory pathway, component PulD K02453 - - 0.000000000000000000000002078 106.0
WH3_k127_1820242_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 2.301e-287 889.0
WH3_k127_1820242_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 1.651e-225 706.0
WH3_k127_1820242_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 499.0
WH3_k127_1820242_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 459.0
WH3_k127_1820242_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 367.0
WH3_k127_1820242_5 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 307.0
WH3_k127_1820242_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008573 271.0
WH3_k127_1820242_7 protein conserved in bacteria K15539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001719 277.0
WH3_k127_1820242_8 type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009327 266.0
WH3_k127_1820242_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000002181 63.0
WH3_k127_1869023_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 582.0
WH3_k127_1869023_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 341.0
WH3_k127_1869023_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000001411 162.0
WH3_k127_1943562_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 497.0
WH3_k127_1943562_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 497.0
WH3_k127_1943562_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 346.0
WH3_k127_1943562_3 peptidase - - - 0.00000000000000001063 86.0
WH3_k127_1998038_0 aminotransferase K14260 - 2.6.1.2,2.6.1.66 8.361e-236 738.0
WH3_k127_1998038_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000001657 102.0
WH3_k127_1998038_2 Lysophospholipase L1 and related esterases - - - 0.00000000000000000123 99.0
WH3_k127_2015462_0 Protein of unknown function (DUF1298) - - - 6.804e-274 848.0
WH3_k127_2015462_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 3.912e-264 818.0
WH3_k127_2015462_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids - - - 2.782e-198 624.0
WH3_k127_2015462_3 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 353.0
WH3_k127_2024258_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 2.404e-264 822.0
WH3_k127_2024258_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 582.0
WH3_k127_2024258_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000001088 227.0
WH3_k127_2032731_0 Lytic murein transglycosylase K08309 - - 1.733e-290 917.0
WH3_k127_2032731_1 GGDEF domain - - - 6.876e-249 800.0
WH3_k127_2032731_2 endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 309.0
WH3_k127_2032731_3 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000003117 131.0
WH3_k127_2032731_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000009227 93.0
WH3_k127_2086356_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1487.0
WH3_k127_2086356_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 1.198e-199 627.0
WH3_k127_2086356_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000000000000000000000006611 189.0
WH3_k127_2086356_3 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000001207 165.0
WH3_k127_2086356_4 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000000000000001024 142.0
WH3_k127_2106050_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1170.0
WH3_k127_2106050_1 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 5.495e-248 774.0
WH3_k127_2106050_2 Diguanylate cyclase - - - 0.00000000000000000000004061 111.0
WH3_k127_2151882_0 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00161 - 1.2.4.1 8.701e-224 699.0
WH3_k127_2151882_1 Lamin Tail Domain K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 336.0
WH3_k127_2151882_2 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000001891 185.0
WH3_k127_2248189_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K04090 - 1.2.7.8 0.0 1141.0
WH3_k127_2248189_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005837 263.0
WH3_k127_2256810_0 TonB-dependent Receptor Plug Domain K02014 - - 0.0 1144.0
WH3_k127_2256810_1 transporter - - - 5.701e-260 808.0
WH3_k127_2256810_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 542.0
WH3_k127_2256810_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 523.0
WH3_k127_2256810_4 COG0591 Na proline symporter - - - 0.0000000000000000000000000000009209 121.0
WH3_k127_2258789_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 1.182e-274 852.0
WH3_k127_2258789_1 Major Facilitator Superfamily K03301 - - 1.972e-212 668.0
WH3_k127_2258789_2 Peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 609.0
WH3_k127_2274881_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 440.0
WH3_k127_2274881_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 372.0
WH3_k127_2274881_2 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 376.0
WH3_k127_2274881_3 UPF0056 membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003148 261.0
WH3_k127_2274881_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000000001433 192.0
WH3_k127_2286257_0 Outer membrane receptor - - - 0.0 1387.0
WH3_k127_2286257_1 COG0457 FOG TPR repeat - - - 3.787e-276 870.0
WH3_k127_2305914_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.572e-261 816.0
WH3_k127_2305914_1 ATP-binding protein K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 475.0
WH3_k127_2305914_2 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 364.0
WH3_k127_2305914_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002546 276.0
WH3_k127_2305914_4 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000002293 224.0
WH3_k127_2305914_5 NlpE N-terminal domain - - - 0.000000000000000000000000000006958 126.0
WH3_k127_2331094_0 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 2.406e-304 946.0
WH3_k127_2331094_1 Belongs to the UPF0061 (SELO) family - - - 4.144e-247 771.0
WH3_k127_2331094_2 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 548.0
WH3_k127_2413682_0 TolQ protein K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 420.0
WH3_k127_2413682_1 Biopolymer transport protein K03560 - - 0.000000000000000000000000000000000000000000000000000000000003209 214.0
WH3_k127_2413682_2 Acyl-CoA thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000006773 184.0
WH3_k127_2413682_3 Membrane protein TolA K03646 - - 0.000000000000000000000000001421 115.0
WH3_k127_2413682_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000006691 65.0
WH3_k127_2431622_0 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 412.0
WH3_k127_2431622_1 General secretion pathway protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000006661 233.0
WH3_k127_2431622_2 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000001338 165.0
WH3_k127_2446026_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.38e-210 654.0
WH3_k127_2446026_1 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 531.0
WH3_k127_2446026_2 SURF1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 327.0
WH3_k127_2446026_3 cytochrome c oxidase assembly protein K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 297.0
WH3_k127_2446026_4 signal sequence binding - - - 0.00000000000000000000000000000000000000000000000000001344 201.0
WH3_k127_2446026_5 Protein of unknown function (DUF2909) - - - 0.000000000000000000000000000001776 137.0
WH3_k127_2501786_0 Polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 549.0
WH3_k127_2501786_1 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000001328 203.0
WH3_k127_2514713_0 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 507.0
WH3_k127_2514713_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000231 260.0
WH3_k127_2535145_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04487 - 2.8.1.7 1.612e-205 651.0
WH3_k127_2535145_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 487.0
WH3_k127_2535145_2 - - - - 0.000000000000000000000000005278 112.0
WH3_k127_2537229_0 Malic enzyme K00029 - 1.1.1.40 0.0 1088.0
WH3_k127_2537229_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000005487 196.0
WH3_k127_2537788_0 Cytochrome C biogenesis K02198 - - 0.0 1055.0
WH3_k127_2537788_1 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 4.965e-207 649.0
WH3_k127_2537788_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000549 60.0
WH3_k127_2537788_12 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000007051 59.0
WH3_k127_2537788_2 3HB-oligomer hydrolase (3HBOH) K07518 - 3.1.1.22 2.489e-201 631.0
WH3_k127_2537788_3 alpha/beta hydrolase fold K03821 - - 1.567e-200 628.0
WH3_k127_2537788_4 Cytochrome C biogenesis K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 372.0
WH3_k127_2537788_5 Poly(R)-hydroxyalkanoic acid synthase subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 352.0
WH3_k127_2537788_6 Thiol disulfide interchange protein K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 316.0
WH3_k127_2537788_7 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000000000006211 238.0
WH3_k127_2537788_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000008822 228.0
WH3_k127_2537788_9 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000000000000000479 203.0
WH3_k127_2541068_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 437.0
WH3_k127_2541068_1 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000385 254.0
WH3_k127_2541068_2 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002435 251.0
WH3_k127_2541068_3 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000001877 191.0
WH3_k127_2541068_4 - - - - 0.0000000000000000000000000000003526 130.0
WH3_k127_2547823_0 dna polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 524.0
WH3_k127_2547823_1 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 352.0
WH3_k127_2547823_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 321.0
WH3_k127_2547823_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 298.0
WH3_k127_2547823_4 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009477 248.0
WH3_k127_2547823_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000000000000000004684 229.0
WH3_k127_2547823_6 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000189 150.0
WH3_k127_2562573_0 Type II secretion system (T2SS), protein K - - - 0.000000000000000000000000000000007954 140.0
WH3_k127_2562573_1 - - - - 0.00000000000000000000000000009814 129.0
WH3_k127_2562573_2 - - - - 0.00000002013 64.0
WH3_k127_2608664_0 Outer membrane receptor proteins mostly Fe transport - - - 0.0 1395.0
WH3_k127_2608664_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000005868 157.0
WH3_k127_2608664_2 alpha-glucosidase K01187 - 3.2.1.20 0.00000000000000003181 81.0
WH3_k127_2615778_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1729.0
WH3_k127_2615778_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000003917 166.0
WH3_k127_261618_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 516.0
WH3_k127_261618_1 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 464.0
WH3_k127_261618_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 447.0
WH3_k127_261618_3 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000000000000000000000000000006802 210.0
WH3_k127_261618_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000002402 175.0
WH3_k127_2710362_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1850.0
WH3_k127_2710362_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.31e-198 629.0
WH3_k127_2710362_2 Long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 488.0
WH3_k127_2710362_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 459.0
WH3_k127_2710362_4 membrane protein (homolog of Drosophila rhomboid) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 355.0
WH3_k127_2710362_5 Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007629 243.0
WH3_k127_2711908_0 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 5.261e-241 758.0
WH3_k127_2711908_1 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 396.0
WH3_k127_2711908_2 MFS transporter K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 358.0
WH3_k127_2711908_3 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000201 256.0
WH3_k127_2711908_4 - - - - 0.0000000000000000000000000005915 117.0
WH3_k127_2711908_5 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.0000000000000000000000003727 104.0
WH3_k127_2929534_0 Pathogenicity protein K09800 - - 0.0 1172.0
WH3_k127_297310_0 - - - - 0.0000000000000000000000000007294 126.0
WH3_k127_297310_1 Type II secretion system (T2SS), protein K - - - 0.00000000000000003665 89.0
WH3_k127_2978320_0 Putative diguanylate phosphodiesterase - - - 0.0 1060.0
WH3_k127_2978320_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 447.0
WH3_k127_2978320_2 Belongs to the inositol monophosphatase superfamily K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 422.0
WH3_k127_2978320_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 415.0
WH3_k127_2978320_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 312.0
WH3_k127_2981555_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 5.569e-253 786.0
WH3_k127_2981555_1 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 1.016e-250 784.0
WH3_k127_2981555_2 gtp-binding protein K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 323.0
WH3_k127_2981555_3 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 298.0
WH3_k127_2981555_4 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000401 238.0
WH3_k127_3025560_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1356.0
WH3_k127_3121302_0 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 451.0
WH3_k127_3121302_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001293 262.0
WH3_k127_3160914_0 phenazine biosynthesis protein PhzF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 473.0
WH3_k127_3160914_1 phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001035 245.0
WH3_k127_3160914_2 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008634 241.0
WH3_k127_3160914_3 elongation factor G K02355 - - 0.0000000000000000001182 93.0
WH3_k127_3185876_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 6.939e-251 777.0
WH3_k127_3185876_1 Zn-dependent hydrolases including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 386.0
WH3_k127_3185876_2 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 312.0
WH3_k127_3185876_3 COG0607 Rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000000000000001545 182.0
WH3_k127_3185876_4 transcriptional - - - 0.00000000000000000000000000000000000000000001207 169.0
WH3_k127_3185876_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000004846 160.0
WH3_k127_3185876_6 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000000001891 121.0
WH3_k127_3185876_7 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000001392 55.0
WH3_k127_3215814_0 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 3.047e-224 703.0
WH3_k127_3215814_1 ATP-binding protein K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 476.0
WH3_k127_3342730_0 General secretion pathway protein K02453 - - 4.965e-261 813.0
WH3_k127_3427670_0 Histidine kinase - - - 1.52e-237 747.0
WH3_k127_3427670_1 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006071 282.0
WH3_k127_3427670_2 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000001838 108.0
WH3_k127_3427670_3 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000002658 108.0
WH3_k127_3457247_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 370.0
WH3_k127_3457247_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 296.0
WH3_k127_3457247_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000008106 216.0
WH3_k127_3457247_3 membrane K06194 - - 0.0000000000000000000000000000000002588 144.0
WH3_k127_3508672_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.29e-241 753.0
WH3_k127_3508672_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 467.0
WH3_k127_3508672_2 Nucleoside triphosphate K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 444.0
WH3_k127_3508672_3 nucleotidase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 422.0
WH3_k127_3508672_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 423.0
WH3_k127_3508672_5 protein-glutamate methylesterase K06597 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 367.0
WH3_k127_3508672_6 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 353.0
WH3_k127_3508672_7 ADP-ribose diphosphatase K08312 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 329.0
WH3_k127_3508672_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 313.0
WH3_k127_3508672_9 Two component signalling adaptor domain K06598 - - 0.00000000000000000000000000000000000000000000000000000000000000000003163 239.0
WH3_k127_3521711_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000001308 213.0
WH3_k127_3521711_1 Ribonucleotide reductase subunit alpha - - - 0.0000000000000000000000000000000000000004319 153.0
WH3_k127_3521711_2 LacY proton/sugar symporter K02575 - - 0.00000000000000000000000000000003317 126.0
WH3_k127_3556501_0 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 517.0
WH3_k127_3556501_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 461.0
WH3_k127_3556501_2 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 384.0
WH3_k127_3556501_3 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000000000000000000000000000000002126 215.0
WH3_k127_3556501_4 Belongs to the transcriptional regulatory Fis family K03557 GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0032991,GO:0032993,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815 - 0.00000000000000000000000000000000000003198 145.0
WH3_k127_3556772_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 557.0
WH3_k127_3556772_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 403.0
WH3_k127_3556772_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 361.0
WH3_k127_3561168_0 aminopeptidase n - - - 5.694e-241 751.0
WH3_k127_3561168_1 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 547.0
WH3_k127_3561168_10 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 296.0
WH3_k127_3561168_11 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000222 279.0
WH3_k127_3561168_12 Purine nucleoside phosphorylase K03784 GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
WH3_k127_3561168_13 - - - - 0.0000000000000000000000000000000000000000000000000000000005349 208.0
WH3_k127_3561168_14 Domain of unknown function (DUF3817) - - - 0.0000000000000000000000000000000000000001452 155.0
WH3_k127_3561168_15 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000366 156.0
WH3_k127_3561168_16 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000117 104.0
WH3_k127_3561168_18 - - - - 0.0000000001002 72.0
WH3_k127_3561168_19 - - - - 0.000000000145 64.0
WH3_k127_3561168_2 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 486.0
WH3_k127_3561168_20 Methyltransferase type 12 - - - 0.0005415 48.0
WH3_k127_3561168_3 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 481.0
WH3_k127_3561168_4 Methyltransferase K06983 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 453.0
WH3_k127_3561168_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 412.0
WH3_k127_3561168_6 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 406.0
WH3_k127_3561168_7 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 373.0
WH3_k127_3561168_8 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 334.0
WH3_k127_3561168_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 309.0
WH3_k127_3689764_0 Histidine kinase - - - 1.995e-209 666.0
WH3_k127_3689764_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 432.0
WH3_k127_3689764_2 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 338.0
WH3_k127_3689764_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000002338 201.0
WH3_k127_3698474_0 Prolyl oligopeptidase family - - - 0.0 1024.0
WH3_k127_3698474_1 diguanylate cyclase - - - 0.00000006724 56.0
WH3_k127_3737093_0 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 546.0
WH3_k127_3737093_1 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K07400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 323.0
WH3_k127_3737093_2 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000000000000001687 204.0
WH3_k127_3751585_0 COG0457 FOG TPR repeat - - - 2.354e-227 722.0
WH3_k127_3751585_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 4.195e-200 631.0
WH3_k127_3751585_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 612.0
WH3_k127_3751585_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 402.0
WH3_k127_3751585_4 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005422 257.0
WH3_k127_3752456_0 Prolyl oligopeptidase family - - - 3.462e-211 676.0
WH3_k127_3752456_1 - - - - 0.0000000000000000000000000000000000000000001728 165.0
WH3_k127_3752456_2 ABC transporter transmembrane region - - - 0.000000000000000000000000006594 110.0
WH3_k127_3753358_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0 1157.0
WH3_k127_3753358_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 567.0
WH3_k127_3753358_2 dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 497.0
WH3_k127_3753358_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 459.0
WH3_k127_3753358_5 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 421.0
WH3_k127_3753358_6 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 413.0
WH3_k127_3753358_7 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000117 247.0
WH3_k127_3753358_8 - - - - 0.000000000001464 77.0
WH3_k127_3755058_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 7.829e-308 961.0
WH3_k127_3755058_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.167e-266 831.0
WH3_k127_3755058_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 479.0
WH3_k127_3755058_3 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 313.0
WH3_k127_3755058_4 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004735 245.0
WH3_k127_3755058_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000000000000000000004157 149.0
WH3_k127_3755058_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000004952 144.0
WH3_k127_3788058_0 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 1.239e-281 882.0
WH3_k127_3788058_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 344.0
WH3_k127_3788058_2 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003734 257.0
WH3_k127_3788058_3 Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD K03592 - - 0.000000000000000000000000000000000000001626 152.0
WH3_k127_3788954_0 Patatin-like phospholipase - - - 8.92e-217 678.0
WH3_k127_3788954_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 321.0
WH3_k127_3788954_2 Poly(hydroxyalcanoate) granule associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000139 218.0
WH3_k127_3788954_3 Restriction endonuclease - - - 0.000000000000000000000000000000001165 134.0
WH3_k127_3788954_4 FHA domain - - - 0.000000008282 57.0
WH3_k127_3817126_0 Cardiolipin synthase - - - 2.919e-263 820.0
WH3_k127_3852088_0 Tropinone reductase K08081 - 1.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 468.0
WH3_k127_3852088_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001498 286.0
WH3_k127_3852088_2 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002132 250.0
WH3_k127_3852088_3 - - - - 0.000000000000000000000000001096 113.0
WH3_k127_3854370_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 3.503e-313 963.0
WH3_k127_3854370_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 320.0
WH3_k127_3854370_2 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003537 228.0
WH3_k127_3899827_0 ABC transporter K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006146 278.0
WH3_k127_3899827_1 Sulfotransferase domain - - - 0.00000000000000000000000000000003055 141.0
WH3_k127_3906383_0 Histidine kinase K07641 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 605.0
WH3_k127_3906383_1 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 456.0
WH3_k127_3906383_2 response regulator K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 314.0
WH3_k127_3906383_3 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007786 249.0
WH3_k127_3916246_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1125.0
WH3_k127_3916246_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886,K16066 - 1.1.1.276,1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 429.0
WH3_k127_3916246_2 Cell division protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000008681 236.0
WH3_k127_3916246_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000136 128.0
WH3_k127_3932688_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 461.0
WH3_k127_3932688_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 437.0
WH3_k127_3932688_2 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 346.0
WH3_k127_4005379_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 554.0
WH3_k127_4005379_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 542.0
WH3_k127_4005379_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 527.0
WH3_k127_4017880_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1054.0
WH3_k127_4029482_0 peptidoglycan-binding protein, lysm - - - 8.739e-200 628.0
WH3_k127_4029482_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 514.0
WH3_k127_4029482_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 287.0
WH3_k127_4029482_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000001277 176.0
WH3_k127_4029482_4 DNA processing protein DprA K04096 - - 0.00000000000000000000000008728 112.0
WH3_k127_4047027_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1116.0
WH3_k127_4047027_1 Glutaryl-7-ACA acylase K06978 - - 0.0 1092.0
WH3_k127_4047027_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 504.0
WH3_k127_4047027_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 498.0
WH3_k127_4047027_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 464.0
WH3_k127_4047027_5 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 312.0
WH3_k127_4047027_6 Belongs to the ArsC family - - - 0.00000000000000000000000000000000000000000000000000000000008379 223.0
WH3_k127_4097745_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 461.0
WH3_k127_4097745_1 Peptidyl-prolyl cis-trans K01802,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 332.0
WH3_k127_4097745_2 Protein of unknown function (DUF1289) - - - 0.00000000000000000868 86.0
WH3_k127_4097745_3 - - - - 0.00000000000000001104 95.0
WH3_k127_4097745_4 DNA mismatch repair protein MutT - - - 0.0000000000008714 73.0
WH3_k127_4104727_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 4.076e-244 761.0
WH3_k127_4123379_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.149e-243 758.0
WH3_k127_4123379_1 protein involved in response to NO K07234 - - 1.137e-194 614.0
WH3_k127_4123379_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 435.0
WH3_k127_4123379_3 Invasion gene expression up-regulator, SirB - - - 0.000000000000000000000000000000000000006082 149.0
WH3_k127_4123379_4 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000000000001508 132.0
WH3_k127_4123379_5 Beta-Casp domain - - - 0.0000000000000000001113 90.0
WH3_k127_4185342_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 590.0
WH3_k127_4185342_1 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 309.0
WH3_k127_4185342_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 293.0
WH3_k127_4258882_0 Thiamine pyrophosphate enzyme, central domain K04103 - 4.1.1.74 2.91e-228 715.0
WH3_k127_4258882_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 451.0
WH3_k127_4258882_2 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 393.0
WH3_k127_4258882_3 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000001182 135.0
WH3_k127_4272872_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1117.0
WH3_k127_4272872_1 - - - - 0.000000005121 62.0
WH3_k127_4275234_0 membrane - - - 8.649e-217 682.0
WH3_k127_4275234_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 419.0
WH3_k127_4275234_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000004078 186.0
WH3_k127_4306523_0 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.0 1384.0
WH3_k127_4306523_1 transcriptional regulator K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 610.0
WH3_k127_4306523_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 385.0
WH3_k127_4306523_3 COG0491 Zn-dependent hydrolases, including glyoxylases K17837 - 3.5.2.6 0.0000005352 53.0
WH3_k127_4355827_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.033e-240 746.0
WH3_k127_4355827_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000005454 154.0
WH3_k127_4463438_0 glutamate--cysteine ligase K01919 - 6.3.2.2 3.523e-266 826.0
WH3_k127_4463438_1 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 5.435e-246 775.0
WH3_k127_4463438_2 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 355.0
WH3_k127_4463438_3 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 323.0
WH3_k127_448505_0 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 592.0
WH3_k127_448505_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 378.0
WH3_k127_448505_2 Alpha beta K07018 - - 0.0000000001863 61.0
WH3_k127_448505_3 - - - - 0.000000134 60.0
WH3_k127_4511804_0 Sulfotransferase family - - - 2.799e-224 720.0
WH3_k127_4511804_1 Outer membrane receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 569.0
WH3_k127_4511804_2 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 572.0
WH3_k127_4511804_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001196 312.0
WH3_k127_4511804_4 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002105 260.0
WH3_k127_4511804_5 - - - - 0.0000000000000000000000000000002342 132.0
WH3_k127_4517962_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 544.0
WH3_k127_4517962_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 534.0
WH3_k127_4523066_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1145.0
WH3_k127_4523066_1 TraB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 480.0
WH3_k127_4523066_2 MerR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000002251 231.0
WH3_k127_4523066_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000007598 184.0
WH3_k127_4523066_4 dehydrogenase - - - 0.00005131 46.0
WH3_k127_4523497_0 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 532.0
WH3_k127_4523497_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0016491,GO:0016667,GO:0016671,GO:0020012,GO:0030682,GO:0033744,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0075136 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 320.0
WH3_k127_4523497_2 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 292.0
WH3_k127_4523497_3 peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000004638 250.0
WH3_k127_4523497_4 Adenylate cyclase - - - 0.000000000000000000000000000000004805 142.0
WH3_k127_4542098_0 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 431.0
WH3_k127_4542098_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000001431 204.0
WH3_k127_4543262_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 532.0
WH3_k127_4543262_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000005638 205.0
WH3_k127_4543262_2 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000001575 130.0
WH3_k127_4548678_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 4.489e-200 657.0
WH3_k127_4548678_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 520.0
WH3_k127_4548678_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 413.0
WH3_k127_4548678_3 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003507 267.0
WH3_k127_4548678_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000005191 186.0
WH3_k127_4548678_5 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000008546 156.0
WH3_k127_4585062_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 409.0
WH3_k127_4585062_1 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 308.0
WH3_k127_4585062_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001082 274.0
WH3_k127_4587851_0 phosphate transporter K03306 - - 9.502e-200 626.0
WH3_k127_4587851_1 Hemolysins and related proteins containing CBS domains K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 605.0
WH3_k127_4587851_2 Pit accessory protein K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 333.0
WH3_k127_4587851_3 exopolysaccharide synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000244 229.0
WH3_k127_459943_0 COG2202 FOG PAS PAC domain K21025 - - 2.097e-255 805.0
WH3_k127_459943_1 lysine 2,3-aminomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 508.0
WH3_k127_459943_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 482.0
WH3_k127_459943_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 476.0
WH3_k127_459943_4 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 461.0
WH3_k127_459943_5 Lysine-specific metallo-endopeptidase K08646 - 3.4.24.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 369.0
WH3_k127_459943_6 cytochrome - - - 0.000000000000000000000000000000000000000000000000004555 185.0
WH3_k127_4603304_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 425.0
WH3_k127_4603304_1 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000304 256.0
WH3_k127_4647484_0 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 347.0
WH3_k127_4647484_1 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000008808 255.0
WH3_k127_4647484_2 translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000006898 250.0
WH3_k127_4647484_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000005167 197.0
WH3_k127_4650928_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11745,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002313 252.0
WH3_k127_4650928_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000002283 113.0
WH3_k127_4677977_0 Helicase K03578 - 3.6.4.13 0.0 1978.0
WH3_k127_4677977_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1108.0
WH3_k127_4677977_2 Glycosyl transferase K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 456.0
WH3_k127_4720055_0 Ferrous iron transport protein B K04759 - - 3.854e-315 976.0
WH3_k127_4720055_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 459.0
WH3_k127_4720055_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000000000000000000000000002706 229.0
WH3_k127_4720055_3 - - - - 0.000000000000000000000000000000000000000000000000000007588 201.0
WH3_k127_4720055_4 - - - - 0.00000000000000000001038 108.0
WH3_k127_4720055_5 ferrous iron transport protein K04758 - - 0.0000000000000000001217 89.0
WH3_k127_4786732_0 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 2.051e-233 729.0
WH3_k127_4786732_1 PilZ domain - - - 0.000000000000000000000000000000002255 132.0
WH3_k127_4857688_0 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 448.0
WH3_k127_4857688_1 cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 369.0
WH3_k127_4857688_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 366.0
WH3_k127_4857688_3 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.00001681 48.0
WH3_k127_4976077_0 Na dependent nucleoside transporter K03317 - - 8.971e-232 723.0
WH3_k127_4976077_1 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 541.0
WH3_k127_4976077_2 potassium channel beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 514.0
WH3_k127_4976077_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 486.0
WH3_k127_4976077_4 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 287.0
WH3_k127_4976077_5 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007608 252.0
WH3_k127_4976077_6 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000001232 247.0
WH3_k127_4976077_7 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000005159 84.0
WH3_k127_4987151_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.417e-317 976.0
WH3_k127_5002730_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 439.0
WH3_k127_5002730_1 Acyltransferase family - - - 0.000000000000000000000000000000366 126.0
WH3_k127_5011833_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 7.214e-194 626.0
WH3_k127_5011833_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 317.0
WH3_k127_5011833_2 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006467 281.0
WH3_k127_5011833_3 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000000000001668 164.0
WH3_k127_5011833_4 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000003818 154.0
WH3_k127_5011833_5 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000002372 151.0
WH3_k127_5011833_6 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000001157 139.0
WH3_k127_5011833_7 4Fe-4S binding domain - - - 0.0000000000000000000000000001074 119.0
WH3_k127_5011833_8 Uncharacterized conserved protein (DUF2249) - - - 0.00000000005525 72.0
WH3_k127_5016273_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.044e-209 656.0
WH3_k127_5016273_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 382.0
WH3_k127_5016273_2 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000000000000002482 188.0
WH3_k127_5016273_3 RNA-binding protein K07574 - - 0.0000000000000000000000000000000000000000000025 172.0
WH3_k127_5016610_0 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 484.0
WH3_k127_5016610_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001084 253.0
WH3_k127_5016610_2 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000002438 163.0
WH3_k127_5024783_0 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 395.0
WH3_k127_5024783_1 metallo-beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 290.0
WH3_k127_5024783_2 MAPEG family - - - 0.000000000000000000000000000000000000000000000000000000000000641 212.0
WH3_k127_5024811_0 protease - - - 3.698e-209 652.0
WH3_k127_5024811_1 protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 354.0
WH3_k127_503844_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0 1226.0
WH3_k127_503844_1 Catalyzes the reversible formation of glyoxylate and succinate from isocitrate K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 517.0
WH3_k127_503844_2 Cyclic nucleotide-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 456.0
WH3_k127_503844_3 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 407.0
WH3_k127_503844_4 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 393.0
WH3_k127_503844_5 - - - - 0.0008963 51.0
WH3_k127_5047652_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 379.0
WH3_k127_5047652_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 326.0
WH3_k127_5047652_2 EVE domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 281.0
WH3_k127_5047652_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000016 259.0
WH3_k127_5047652_4 - - - - 0.00000000000000000000000000000000000000000000000000000616 202.0
WH3_k127_5047652_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000005811 124.0
WH3_k127_5047652_6 TIGRFAM TIGR02449 family protein K09892 - - 0.000000000000000007521 95.0
WH3_k127_5062227_0 Beta-Casp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 454.0
WH3_k127_5062227_1 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 443.0
WH3_k127_5074633_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 4.367e-210 656.0
WH3_k127_5074633_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 569.0
WH3_k127_5074633_2 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008270,GO:0008798,GO:0016787,GO:0019538,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 566.0
WH3_k127_5074633_3 Peptidase family S51 K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 408.0
WH3_k127_5074633_4 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 349.0
WH3_k127_5074633_5 Prokaryotic glutathione synthetase, ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000004083 224.0
WH3_k127_5125397_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.322e-254 803.0
WH3_k127_5125397_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 3.12e-226 709.0
WH3_k127_5125397_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 3.039e-203 637.0
WH3_k127_5125397_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 396.0
WH3_k127_5125397_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme - - - 0.00000000000000000000000000000000000000000000001744 175.0
WH3_k127_5125397_5 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000002838 117.0
WH3_k127_5125397_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000001933 85.0
WH3_k127_5159660_0 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 589.0
WH3_k127_5159660_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 520.0
WH3_k127_5159660_2 Uncharacterized protein conserved in bacteria (DUF2272) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 447.0
WH3_k127_5159660_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000102 261.0
WH3_k127_5159660_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000003649 84.0
WH3_k127_5159660_6 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000002645 63.0
WH3_k127_5196715_0 chemotaxis protein K02660 - - 1.347e-198 631.0
WH3_k127_5196715_1 chemotaxis signal transduction protein K02659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 326.0
WH3_k127_5196715_2 response regulator K02657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002404 246.0
WH3_k127_5196715_3 response K02658 - - 0.000000000000000000000000000000000000000000000000000000000004148 209.0
WH3_k127_5196715_4 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.0000000000000000000000001378 109.0
WH3_k127_5258842_0 MASE1 - - - 1.04e-267 842.0
WH3_k127_5258842_1 Serine dehydratase K01752 - 4.3.1.17 1.517e-246 764.0
WH3_k127_5258842_2 homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 528.0
WH3_k127_5258842_3 cystathionine K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 374.0
WH3_k127_5276346_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 378.0
WH3_k127_5276346_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 359.0
WH3_k127_5300231_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.385e-271 846.0
WH3_k127_5300231_1 trab family - - - 2.558e-219 684.0
WH3_k127_5300231_2 hydrolase, carbon-nitrogen family K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000002323 221.0
WH3_k127_5300231_3 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000009795 136.0
WH3_k127_5305985_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.0 1389.0
WH3_k127_5305985_1 Helicase K03722 - 3.6.4.12 0.0 1065.0
WH3_k127_5305985_2 glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000002365 168.0
WH3_k127_5305985_3 Glycosyl transferase K20444 - - 0.0000000000000000006171 88.0
WH3_k127_5308694_0 alpha-glucosidase K01187 - 3.2.1.20 9.365e-282 889.0
WH3_k127_5308694_1 Major facilitator superfamily K16211 - - 1.77e-278 895.0
WH3_k127_5308694_2 cyclomaltodextrin glucanotransferase K00701 - 2.4.1.19 6.654e-256 802.0
WH3_k127_5308694_3 LacI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 563.0
WH3_k127_5308694_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000004566 92.0
WH3_k127_5308694_5 Domain of unknown function (DUF3372) - - - 0.0003352 48.0
WH3_k127_531852_0 aminotransferase K00812 - 2.6.1.1 6.596e-230 722.0
WH3_k127_531852_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 356.0
WH3_k127_531852_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 308.0
WH3_k127_531852_3 gtp-binding protein K06207 - - 0.00000000000000000000000000000000000000001523 153.0
WH3_k127_5324246_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1262.0
WH3_k127_5324246_1 Participates in both transcription termination and antitermination K02600 - - 2.816e-287 885.0
WH3_k127_5324246_2 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 4.124e-273 846.0
WH3_k127_5324246_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.844e-239 746.0
WH3_k127_5324246_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 497.0
WH3_k127_5324246_5 NADH ubiquinone oxidoreductase subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 339.0
WH3_k127_5324246_6 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 329.0
WH3_k127_5324246_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000000000000001308 192.0
WH3_k127_5324246_8 Bacteriophage replication gene A protein (GPA) - - - 0.00000005122 56.0
WH3_k127_5332157_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 3.061e-308 954.0
WH3_k127_5332157_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 1.011e-216 680.0
WH3_k127_5332157_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000002059 226.0
WH3_k127_5332157_3 Preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000000000000000000000000000007719 179.0
WH3_k127_5332157_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000005139 122.0
WH3_k127_5373662_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0 1308.0
WH3_k127_5373662_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 9.64e-236 737.0
WH3_k127_5373662_2 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000003014 239.0
WH3_k127_542358_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 8.127e-301 929.0
WH3_k127_542358_1 Threonine/Serine exporter, ThrE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 564.0
WH3_k127_542358_2 abc transporter, permease K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 422.0
WH3_k127_542358_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 315.0
WH3_k127_542358_4 dna-binding protein K03746 - - 0.0000000000000000000000000000000000000000004294 161.0
WH3_k127_542358_5 Sigma factor PP2C-like phosphatases - - - 0.00000000000000002056 87.0
WH3_k127_542358_6 Domain of unknown function (DUF4124) - - - 0.00000003936 61.0
WH3_k127_542358_7 Domain of unknown function (DUF4124) - - - 0.0003561 48.0
WH3_k127_5461484_0 diguanylate cyclase - - - 0.0 1253.0
WH3_k127_5461484_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 533.0
WH3_k127_5461484_2 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 460.0
WH3_k127_5461484_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 348.0
WH3_k127_5461484_4 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 319.0
WH3_k127_5461484_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002127 265.0
WH3_k127_5501055_0 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 2.808e-227 713.0
WH3_k127_5501055_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000000002931 144.0
WH3_k127_554222_0 serine protease - - - 0.0 1379.0
WH3_k127_554222_1 Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 334.0
WH3_k127_554222_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000001573 67.0
WH3_k127_5556503_0 Involved in the TonB-independent uptake of proteins K03641 - - 2.709e-229 715.0
WH3_k127_5556503_1 Type II/IV secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 438.0
WH3_k127_5556503_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 423.0
WH3_k127_5556503_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 407.0
WH3_k127_5556503_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 314.0
WH3_k127_5556503_5 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001996 274.0
WH3_k127_557176_0 protein conserved in bacteria - - - 4.232e-296 921.0
WH3_k127_557176_1 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 482.0
WH3_k127_557176_2 Dolichol-phosphate mannosyltransferase K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 436.0
WH3_k127_557176_3 chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 432.0
WH3_k127_557176_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 326.0
WH3_k127_557176_5 membrane - - - 0.0000000000000000000000000000000000000000000000000000005483 203.0
WH3_k127_5574349_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1594.0
WH3_k127_5574349_1 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 4.389e-307 949.0
WH3_k127_5574349_10 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000000000000000003499 177.0
WH3_k127_5574349_11 - - - - 0.0000000000000000000000000000000000001984 149.0
WH3_k127_5574349_12 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000003522 126.0
WH3_k127_5574349_13 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000000000000003515 106.0
WH3_k127_5574349_14 - - - - 0.000000000000006053 81.0
WH3_k127_5574349_2 Cytochrome b(N-terminal)/b6/petB - - - 2.558e-233 760.0
WH3_k127_5574349_3 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 598.0
WH3_k127_5574349_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 430.0
WH3_k127_5574349_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 347.0
WH3_k127_5574349_6 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 332.0
WH3_k127_5574349_7 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003092 288.0
WH3_k127_5574349_8 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000000000000000000000000000001225 239.0
WH3_k127_5574349_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000005105 210.0
WH3_k127_5614552_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 3.925e-260 805.0
WH3_k127_5614552_1 FAD-dependent dehydrogenases K07137 - - 1.576e-215 673.0
WH3_k127_5614552_2 lipolytic protein G-D-S-L family K00612 - - 0.000000000000003757 85.0
WH3_k127_5687171_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 585.0
WH3_k127_5687171_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000002652 224.0
WH3_k127_5687171_3 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000009147 168.0
WH3_k127_5687171_4 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000000000000000000000004744 169.0
WH3_k127_569616_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 611.0
WH3_k127_569616_1 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000012 276.0
WH3_k127_569616_2 Pathogenicity protein K09800 - - 0.000000000000001113 76.0
WH3_k127_5731592_0 Helicase K03579 - 3.6.4.13 0.0 1502.0
WH3_k127_5731592_1 Preprotein translocase subunit TatD K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 490.0
WH3_k127_5731592_2 - - - - 0.00000000000000000000000000003039 121.0
WH3_k127_5731592_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000004538 71.0
WH3_k127_575182_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 416.0
WH3_k127_575182_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 333.0
WH3_k127_575182_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001404 279.0
WH3_k127_5774680_0 aminopeptidase K01262 - 3.4.11.9 3.865e-255 790.0
WH3_k127_5774680_1 Belongs to the UPF0149 family K09895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008897 254.0
WH3_k127_5774680_2 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 0.0000000000000000006039 86.0
WH3_k127_5804749_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 624.0
WH3_k127_5804749_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 370.0
WH3_k127_5804749_2 membrane protein terc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 328.0
WH3_k127_5804749_3 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000000000000154 216.0
WH3_k127_5804749_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000005453 154.0
WH3_k127_58321_0 fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644 503.0
WH3_k127_58321_1 NAD FAD-binding protein K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 407.0
WH3_k127_58321_2 ChrR Cupin-like domain K07167 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001009 288.0
WH3_k127_58321_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001451 266.0
WH3_k127_58321_4 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000002295 245.0
WH3_k127_58321_5 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000000000005738 123.0
WH3_k127_5963344_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.263e-311 958.0
WH3_k127_5992449_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.261e-268 838.0
WH3_k127_5992449_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 360.0
WH3_k127_6043441_0 peptidase - - - 1.694e-200 644.0
WH3_k127_6043441_1 acid dehydrogenase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 627.0
WH3_k127_6043441_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 447.0
WH3_k127_6043441_3 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 425.0
WH3_k127_6043441_4 Thermolysin metallopeptidase, catalytic domain K20273 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 419.0
WH3_k127_6069569_0 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 574.0
WH3_k127_6138704_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 1.205e-248 774.0
WH3_k127_6138704_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000001732 211.0
WH3_k127_61457_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 329.0
WH3_k127_61457_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 286.0
WH3_k127_61457_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000002583 261.0
WH3_k127_61457_3 Belongs to the UPF0758 family K03630 - - 0.000000000001108 78.0
WH3_k127_6164671_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 1.261e-248 774.0
WH3_k127_6164671_1 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 377.0
WH3_k127_6164671_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000005881 166.0
WH3_k127_6207325_0 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 438.0
WH3_k127_6207325_1 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 384.0
WH3_k127_6207325_2 - - - - 0.00000000000000000000008403 104.0
WH3_k127_6207325_3 Uncharacterized protein conserved in bacteria (DUF2239) K09965 - - 0.000000000000006477 77.0
WH3_k127_6209642_0 Belongs to the glutamate synthase family - - - 1.502e-216 675.0
WH3_k127_6209642_1 Sulfate adenylyltransferase subunit 2 K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 482.0
WH3_k127_6238384_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.781e-216 674.0
WH3_k127_6238384_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 484.0
WH3_k127_6238384_2 transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 394.0
WH3_k127_6238384_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 387.0
WH3_k127_6242821_0 Acetyltransferase (GNAT) domain - - - 5.312e-298 925.0
WH3_k127_6242821_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 7.182e-221 687.0
WH3_k127_6242821_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 466.0
WH3_k127_6242821_3 serine threonine protein kinase K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008884 312.0
WH3_k127_6242821_4 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000000000000000001909 194.0
WH3_k127_6242821_5 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000002494 143.0
WH3_k127_6242821_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000006351 92.0
WH3_k127_6248684_0 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 495.0
WH3_k127_6248684_1 - - - - 0.000000000000000000000000000000000000000000003122 169.0
WH3_k127_6248684_2 Catalyzes the reversible formation of glyoxylate and succinate from isocitrate K01637 - 4.1.3.1 0.0000000000000000000000000000000000003895 141.0
WH3_k127_6250078_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 559.0
WH3_k127_6250078_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 347.0
WH3_k127_6250078_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000003785 173.0
WH3_k127_6259804_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 542.0
WH3_k127_6259804_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 337.0
WH3_k127_6398364_0 LuxR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 331.0
WH3_k127_6398364_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 304.0
WH3_k127_6428669_0 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 461.0
WH3_k127_6428669_1 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 469.0
WH3_k127_6428669_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 293.0
WH3_k127_6428669_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000001137 223.0
WH3_k127_6428669_4 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000002662 196.0
WH3_k127_6453328_0 phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 475.0
WH3_k127_6453328_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 471.0
WH3_k127_6453328_2 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 448.0
WH3_k127_6453328_3 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 372.0
WH3_k127_6453328_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 372.0
WH3_k127_6453328_5 Putative DNA-binding domain K09929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 360.0
WH3_k127_6453328_6 EF hand - - - 0.000000000000000000000000000000000000009791 151.0
WH3_k127_6453328_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000009445 53.0
WH3_k127_6457673_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1226.0
WH3_k127_6457673_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000003849 228.0
WH3_k127_6459899_0 Belongs to the GPI family K01810 - 5.3.1.9 2.647e-212 678.0
WH3_k127_6459899_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 422.0
WH3_k127_6459899_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000001044 239.0
WH3_k127_6459899_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000002856 105.0
WH3_k127_6461838_0 Oxidoreductase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 411.0
WH3_k127_6461838_1 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 421.0
WH3_k127_6461838_2 RmuC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 413.0
WH3_k127_647538_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 396.0
WH3_k127_647538_1 esterase K12686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 376.0
WH3_k127_647538_2 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000000000000008699 106.0
WH3_k127_6507026_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 460.0
WH3_k127_6507026_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 389.0
WH3_k127_6507026_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 351.0
WH3_k127_6507026_3 membrane - - - 0.000000000000000000000000000000000000002268 155.0
WH3_k127_6507026_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000266 84.0
WH3_k127_6528341_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.564e-250 786.0
WH3_k127_6528341_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 418.0
WH3_k127_6528341_2 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000288 284.0
WH3_k127_6528341_3 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000000000000000000000000006756 224.0
WH3_k127_6528341_5 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000002502 117.0
WH3_k127_6528341_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000001163 64.0
WH3_k127_653481_0 Methyltransferase K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 412.0
WH3_k127_653481_1 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 350.0
WH3_k127_653481_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005139 270.0
WH3_k127_653481_3 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000002169 132.0
WH3_k127_6539077_0 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 1.645e-262 814.0
WH3_k127_6539077_1 MFS transporter permease - - - 1.812e-210 659.0
WH3_k127_6539077_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - - 6.524e-197 616.0
WH3_k127_6539077_3 periplasmic protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 541.0
WH3_k127_6539077_4 Protein of unknown function (DUF1615) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 496.0
WH3_k127_6539077_5 Predicted permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 325.0
WH3_k127_6539077_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006731 258.0
WH3_k127_6539077_7 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000003049 193.0
WH3_k127_6539077_8 - - - - 0.000000000000000000000000000000000000000000000000002954 188.0
WH3_k127_6539077_9 Thioredoxin domain - - - 0.0000000000000000000000000000000005997 141.0
WH3_k127_6547244_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1157.0
WH3_k127_6547244_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1069.0
WH3_k127_6547244_10 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000000000000000001924 180.0
WH3_k127_6547244_11 Ribosomal protein L31 K02909 - - 0.0000000000000000000000000000000000000000000319 162.0
WH3_k127_6547244_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.116e-261 808.0
WH3_k127_6547244_3 Belongs to the IUNH family K01239 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 513.0
WH3_k127_6547244_4 stress-induced protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 467.0
WH3_k127_6547244_5 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 363.0
WH3_k127_6547244_6 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 337.0
WH3_k127_6547244_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 301.0
WH3_k127_6547244_8 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 253.0
WH3_k127_6547244_9 endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000009084 196.0
WH3_k127_655562_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 3.91e-274 861.0
WH3_k127_655562_1 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 586.0
WH3_k127_655562_2 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 377.0
WH3_k127_655562_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004295 280.0
WH3_k127_655562_4 SufE protein probably involved in Fe-S center assembly K02426 - - 0.0000000000000000000000000000000000000000000000000000000000000000006051 236.0
WH3_k127_655562_5 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000002362 162.0
WH3_k127_6564261_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 542.0
WH3_k127_6564261_1 glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 532.0
WH3_k127_6564261_10 - - - - 0.00000000000000000000000000004413 121.0
WH3_k127_6564261_11 - - - - 0.0005638 48.0
WH3_k127_6564261_2 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 488.0
WH3_k127_6564261_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 284.0
WH3_k127_6564261_4 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002921 276.0
WH3_k127_6564261_5 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000002817 254.0
WH3_k127_6564261_6 - - - - 0.000000000000000000000000000000000000000000000000000004192 197.0
WH3_k127_6564261_7 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000001086 186.0
WH3_k127_6564261_8 ferredoxin - - - 0.00000000000000000000000000000000000000000002838 163.0
WH3_k127_6564261_9 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000001005 162.0
WH3_k127_6569472_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 471.0
WH3_k127_6569472_1 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 471.0
WH3_k127_6569472_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 410.0
WH3_k127_6569472_3 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 426.0
WH3_k127_6569472_4 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 357.0
WH3_k127_6585021_0 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 297.0
WH3_k127_6585021_1 Protein chain release factor B K15034 - - 0.000000000000000000000000000000000000000000000000000000000000000000002765 236.0
WH3_k127_6585021_2 pseudouridylate synthase K06175 - 5.4.99.26 0.0000000000000000000000000000000000000002057 150.0
WH3_k127_6591052_0 NAD FAD-binding protein K06954 - - 3.729e-209 652.0
WH3_k127_6591052_1 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 414.0
WH3_k127_6591052_2 synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 298.0
WH3_k127_6592397_0 glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1216.0
WH3_k127_6592397_1 acyl-CoA dehydrogenase - - - 2.194e-236 739.0
WH3_k127_6592397_2 Methyltransferase K00548 - 2.1.1.13 8.429e-204 646.0
WH3_k127_6592397_3 ArsR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 558.0
WH3_k127_6598982_0 Peptidase family M1 domain - - - 0.0 1130.0
WH3_k127_6598982_1 Beta-lactamase - - - 5.044e-230 715.0
WH3_k127_6598982_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 301.0
WH3_k127_6598982_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009215 237.0
WH3_k127_6601965_0 Amidohydrolase family - - - 1.407e-264 836.0
WH3_k127_6601965_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 7.237e-238 749.0
WH3_k127_6601965_2 transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 382.0
WH3_k127_6601965_3 Phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 318.0
WH3_k127_6619766_0 Phosphate starvation protein PhoH K07175 - - 4.519e-282 869.0
WH3_k127_6619766_1 Sulfate transporter K03321 - - 6.455e-214 679.0
WH3_k127_6619766_10 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 321.0
WH3_k127_6619766_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 319.0
WH3_k127_6619766_12 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005718 250.0
WH3_k127_6619766_2 catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 2.272e-210 659.0
WH3_k127_6619766_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 4.963e-203 655.0
WH3_k127_6619766_4 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 573.0
WH3_k127_6619766_5 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 505.0
WH3_k127_6619766_6 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 391.0
WH3_k127_6619766_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 364.0
WH3_k127_6619766_8 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 360.0
WH3_k127_6619766_9 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 338.0
WH3_k127_6636281_0 methyl-accepting chemotaxis protein K07315 - 3.1.3.3 9.187e-228 731.0
WH3_k127_6636281_1 dna polymerase K02337 - 2.7.7.7 7.74e-226 706.0
WH3_k127_6636281_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 602.0
WH3_k127_6636281_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 309.0
WH3_k127_6636281_4 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000000000000000000000006704 170.0
WH3_k127_6636281_5 - - - - 0.000000000000000004971 87.0
WH3_k127_6654174_0 Dak2 K07030 - - 4.064e-270 850.0
WH3_k127_6654174_1 two-component system sensor protein K07637 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 432.0
WH3_k127_6654174_2 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 398.0
WH3_k127_6654174_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000181 283.0
WH3_k127_666365_0 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 583.0
WH3_k127_666365_1 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 307.0
WH3_k127_666365_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000001213 256.0
WH3_k127_666365_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000003035 233.0
WH3_k127_6718060_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 584.0
WH3_k127_6718060_1 antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 375.0
WH3_k127_6718060_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 347.0
WH3_k127_6723099_0 E3 component of 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 3.302e-293 904.0
WH3_k127_6723099_1 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000004619 145.0
WH3_k127_6778528_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 5.605e-237 744.0
WH3_k127_6778528_1 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 539.0
WH3_k127_6778528_2 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000001816 266.0
WH3_k127_6778528_3 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.00000000000000000000000000000000000000000000000000000000000001745 229.0
WH3_k127_6778528_4 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000000002061 130.0
WH3_k127_6778528_5 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.000000457 55.0
WH3_k127_6847199_0 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 404.0
WH3_k127_6847199_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001191 280.0
WH3_k127_6847199_2 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002456 255.0
WH3_k127_6847199_3 - - - - 0.000000000000000000000000000000000000000000000002536 179.0
WH3_k127_6867724_0 Carboxypeptidase - - - 7.158e-277 863.0
WH3_k127_6867724_1 Transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 381.0
WH3_k127_6867724_2 glutathione s-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 336.0
WH3_k127_6867724_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 299.0
WH3_k127_6943575_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 4.069e-195 610.0
WH3_k127_6943575_1 COG0258 5'-3' exonuclease (including N-terminal domain of PolI) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 569.0
WH3_k127_6943575_2 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 280.0
WH3_k127_6943575_3 DNA mismatch repair protein MutT K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000004477 181.0
WH3_k127_6943575_4 NADP transhydrogenase K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000173 167.0
WH3_k127_6943575_5 DNA mismatch repair protein MutT K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000469 158.0
WH3_k127_6944729_0 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 1.423e-243 768.0
WH3_k127_6944729_1 de-polymerase K05973 - 3.1.1.75 5.246e-198 619.0
WH3_k127_6944729_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 482.0
WH3_k127_6944729_3 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 331.0
WH3_k127_6944729_4 membrane K08973 - - 0.0000000000000000000000000000000000000000000000000000004733 203.0
WH3_k127_6987747_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1159.0
WH3_k127_6987747_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000009744 254.0
WH3_k127_6993140_0 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 626.0
WH3_k127_6993140_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 440.0
WH3_k127_6993140_2 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 381.0
WH3_k127_6993140_3 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000005865 87.0
WH3_k127_6993140_4 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000007093 69.0
WH3_k127_7014731_0 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 2.205e-216 685.0
WH3_k127_7014731_1 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 281.0
WH3_k127_7057076_0 Putative diguanylate phosphodiesterase - - - 1.07e-240 756.0
WH3_k127_7057076_1 amino acid K03294 - - 9.704e-236 742.0
WH3_k127_7057076_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 425.0
WH3_k127_7057076_3 Elongation factor P K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 358.0
WH3_k127_7057076_4 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002035 274.0
WH3_k127_7057076_5 receptor K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002189 251.0
WH3_k127_7057076_6 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03828 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002625 259.0
WH3_k127_7074295_0 Belongs to the ParA family K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 484.0
WH3_k127_7074295_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002582 251.0
WH3_k127_7074295_2 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000000000000000000008464 194.0
WH3_k127_7074295_3 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000000000000000000000003937 152.0
WH3_k127_7095212_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.519e-205 649.0
WH3_k127_7095212_1 abc transporter atp-binding protein K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 301.0
WH3_k127_711087_0 2,4-dienoyl-coa reductase K00219 - 1.3.1.34 0.0 1145.0
WH3_k127_711087_1 also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity K01659 - 2.3.3.5 2.252e-234 726.0
WH3_k127_711087_2 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 574.0
WH3_k127_711087_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 319.0
WH3_k127_711087_4 Cell Wall - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006451 269.0
WH3_k127_711087_5 Ion channel - - - 0.00000000000000000000000000005057 128.0
WH3_k127_7118946_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 480.0
WH3_k127_7118946_1 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 396.0
WH3_k127_7118946_2 DUF167 K09131 - - 0.000000000000000000000000000000001169 131.0
WH3_k127_7118946_3 - - - - 0.00000000008814 69.0
WH3_k127_7127296_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 578.0
WH3_k127_7127296_1 Belongs to the mandelate racemase muconate lactonizing enzyme family K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 539.0
WH3_k127_7127296_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 373.0
WH3_k127_7127296_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 362.0
WH3_k127_7127296_4 helix_turn_helix, Lux Regulon K20264 - - 0.00000000000002294 75.0
WH3_k127_7138496_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.671e-309 952.0
WH3_k127_7138496_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 543.0
WH3_k127_7138496_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 460.0
WH3_k127_7138496_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000004256 261.0
WH3_k127_714867_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 465.0
WH3_k127_714867_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 298.0
WH3_k127_714867_2 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000123 152.0
WH3_k127_7212538_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 9.119e-241 747.0
WH3_k127_7212538_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 473.0
WH3_k127_7212538_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 384.0
WH3_k127_7212538_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002864 283.0
WH3_k127_7267625_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 402.0
WH3_k127_7267625_1 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 393.0
WH3_k127_7267625_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 361.0
WH3_k127_7267625_3 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 353.0
WH3_k127_7267625_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000003302 198.0
WH3_k127_7274211_0 Belongs to the AB hydrolase superfamily. MetX family K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 503.0
WH3_k127_7274211_1 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 384.0
WH3_k127_7274211_2 cystathionine K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004419 281.0
WH3_k127_7274211_3 Histidine kinase K07778 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000002274 232.0
WH3_k127_7274211_4 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002892 237.0
WH3_k127_7274211_5 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000002129 227.0
WH3_k127_7274211_6 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000000000000000000000000000000000000000000000002752 196.0
WH3_k127_7302201_0 diguanylate cyclase - - - 2.762e-243 786.0
WH3_k127_7302201_1 Beta-lactamase - - - 1.405e-232 734.0
WH3_k127_7302201_2 Iron-regulated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 388.0
WH3_k127_7306984_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 7.93e-202 629.0
WH3_k127_7306984_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 561.0
WH3_k127_7306984_2 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007751 264.0
WH3_k127_7309588_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 362.0
WH3_k127_7309588_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003703 250.0
WH3_k127_7309588_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002027 244.0
WH3_k127_7309588_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000002977 152.0
WH3_k127_7377145_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 510.0
WH3_k127_7377145_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 317.0
WH3_k127_7377145_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 320.0
WH3_k127_7386212_0 ABC transporter K06147 - - 4.999e-311 959.0
WH3_k127_7386212_1 - - - - 0.000000000000000001421 87.0
WH3_k127_7386212_2 Cold shock protein domain - - - 0.00000000000000106 76.0
WH3_k127_740332_0 Protein tyrosine kinase K11912 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 471.0
WH3_k127_740332_1 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006337 243.0
WH3_k127_740332_2 Thioredoxin K05838 - - 0.0000000000000001084 79.0
WH3_k127_7461224_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 422.0
WH3_k127_7461224_1 - - - - 0.00000000000000000000000000000000000000000000000000000000009911 212.0
WH3_k127_7461224_2 DUF167 K09131 - - 0.0000000000000000000000000000000008366 131.0
WH3_k127_7461224_3 Curli production assembly/transport component CsgG - - - 0.000000000001361 67.0
WH3_k127_7468192_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 394.0
WH3_k127_7468192_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001753 273.0
WH3_k127_7468192_2 Glutamyl-tRNA amidotransferase K09117 - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
WH3_k127_7468192_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000004961 68.0
WH3_k127_7474070_0 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 449.0
WH3_k127_7474070_1 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 414.0
WH3_k127_7474070_2 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000001245 221.0
WH3_k127_7481358_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 486.0
WH3_k127_7481358_1 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 352.0
WH3_k127_7481358_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000004472 242.0
WH3_k127_7481358_3 Protein of unknown function (DUF3301) - - - 0.00000000000000000000000000000000000000000005209 175.0
WH3_k127_7481358_4 Trm112p-like protein - - - 0.0000000000000000000000000000000003197 141.0
WH3_k127_7518982_0 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 375.0
WH3_k127_7518982_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 354.0
WH3_k127_7518982_2 Protein tyrosine kinase K11912 - 2.7.11.1 0.000000000000000000000000000000000000000000008903 168.0
WH3_k127_7558864_0 Belongs to the arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 548.0
WH3_k127_7558864_1 - - - - 0.00000000000000000000000003479 109.0
WH3_k127_7558864_2 Sporulation related domain - - - 0.0000001811 53.0
WH3_k127_7558864_3 Entericidin EcnA/B family - - - 0.000009694 57.0
WH3_k127_7571901_0 COG0591 Na proline symporter - - - 0.0 1377.0
WH3_k127_7615465_0 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 568.0
WH3_k127_7615465_1 DNA-(Apurinic or apyrimidinic site) lyase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 405.0
WH3_k127_7615465_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000001944 218.0
WH3_k127_7629692_0 DNA helicase K03654 - 3.6.4.12 5.022e-285 880.0
WH3_k127_7629692_1 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 286.0
WH3_k127_7629692_2 Helicase K03578 - 3.6.4.13 0.00000000000000000000000000000000000000000002091 164.0
WH3_k127_7648890_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 421.0
WH3_k127_7648890_1 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001723 258.0
WH3_k127_7648890_2 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001087 204.0
WH3_k127_7648890_3 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000001872 152.0
WH3_k127_7711329_0 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 315.0
WH3_k127_7711329_1 Cell division protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 310.0
WH3_k127_7844550_0 peptidylprolyl isomerase K03770 - 5.2.1.8 1.355e-272 854.0
WH3_k127_7844550_1 Catalyzes a key regulatory step in fatty acid biosynthesis K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 471.0
WH3_k127_7844550_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000000000001041 165.0
WH3_k127_7944113_0 glutamate dehydrogenase K15371 - 1.4.1.2 2.26e-295 911.0
WH3_k127_7944113_1 5'-nucleotidase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 510.0
WH3_k127_7944113_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 404.0
WH3_k127_7985563_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1479.0
WH3_k127_7985563_1 Quinone oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 586.0
WH3_k127_7985563_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 565.0
WH3_k127_7985563_3 Cytochrome C biogenesis protein K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 507.0
WH3_k127_7985563_4 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 468.0
WH3_k127_7985563_5 Protein of unknown function (DUF3011) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 334.0
WH3_k127_7985563_6 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 311.0
WH3_k127_7985563_7 Peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009072 251.0
WH3_k127_7985563_8 Chemotaxis protein CheY K02658 - - 0.0000000000000000000000000000000000000000000000000000000000000004996 226.0
WH3_k127_804582_0 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 436.0
WH3_k127_804582_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 364.0
WH3_k127_8098844_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 589.0
WH3_k127_8098844_1 Polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 546.0
WH3_k127_8098844_2 regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 403.0
WH3_k127_8098844_3 acetyltransferase K06977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 339.0
WH3_k127_8098844_4 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000000004789 196.0
WH3_k127_8106085_0 Potassium transporter TrkA - - - 3.63e-283 877.0
WH3_k127_8106085_1 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 582.0
WH3_k127_8106085_2 fumarylacetoacetate hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 355.0
WH3_k127_8106085_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000001353 194.0
WH3_k127_8106085_4 ferredoxin - - - 0.0000000000000000000000000000000000003252 158.0
WH3_k127_8106085_5 - - - - 0.0000000000000000000008498 99.0
WH3_k127_8174288_0 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 587.0
WH3_k127_8174288_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 378.0
WH3_k127_8174288_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000003047 182.0
WH3_k127_8174288_3 Barstar (barnase inhibitor) - - - 0.0000000000000000000000000000000000000000000741 173.0
WH3_k127_8174288_4 ribonuclease - - - 0.0000000000000000000000000000000000000000001508 169.0
WH3_k127_8174288_5 Preprotein translocase subunit SecG K03075 - - 0.000000000000000000000000000000000002508 144.0
WH3_k127_8174288_7 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000639 75.0
WH3_k127_8228569_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1566.0
WH3_k127_8228569_1 TonB dependent receptor - - - 0.0 1263.0
WH3_k127_8228569_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0042802,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 2.003e-211 662.0
WH3_k127_8228569_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 372.0
WH3_k127_8228569_4 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 286.0
WH3_k127_8228569_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007728 276.0
WH3_k127_8229577_0 - - - - 1.017e-250 778.0
WH3_k127_8229577_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 452.0
WH3_k127_8229577_2 Belongs to the Orn Lys Arg decarboxylase class-II family K12526 - 2.7.2.4,4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 347.0
WH3_k127_8338553_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 7.927e-285 880.0
WH3_k127_8338553_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 524.0
WH3_k127_8338553_2 May be involved in recombination K03554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 515.0
WH3_k127_8338553_3 Protein of unknown function (DUF465) - - - 0.000000000000000000000002521 117.0
WH3_k127_839875_0 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 382.0
WH3_k127_839875_1 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 359.0
WH3_k127_839875_2 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 352.0
WH3_k127_8472090_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.087e-218 683.0
WH3_k127_8472090_1 Peptidoglycan polymerase that is essential for cell division K03588 - - 1.471e-216 698.0
WH3_k127_8472090_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 612.0
WH3_k127_8472090_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 489.0
WH3_k127_8472090_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000001584 156.0
WH3_k127_8551062_0 ABC transporter substrate-binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 448.0
WH3_k127_8551062_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 315.0
WH3_k127_8551062_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 314.0
WH3_k127_8551062_3 Domain of unknown function (DUF4426) - - - 0.0000000000000000000000000000000003443 140.0
WH3_k127_8551062_4 Dodecin K09165 - - 0.00000000000000000000000000000466 120.0
WH3_k127_8551062_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000002 102.0
WH3_k127_8553293_0 Dipeptidyl-peptidase 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001668 265.0
WH3_k127_8553293_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000003834 254.0
WH3_k127_8553293_2 Protein of unknown function (DUF3224) - - - 0.00000000000000000000000000000000000000000000000000000000000000004803 231.0
WH3_k127_8556628_0 Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01867 - 6.1.1.2 2.71e-232 728.0
WH3_k127_8556628_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 447.0
WH3_k127_8556628_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000008113 233.0
WH3_k127_8570946_0 deiminase K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 587.0
WH3_k127_8570946_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 504.0
WH3_k127_8570946_2 proteins of the AP superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 452.0
WH3_k127_8570946_3 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 387.0
WH3_k127_8570946_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000001912 279.0
WH3_k127_8624412_0 Involved in the biosynthesis of porphyrin-containing compound - - - 7.051e-219 681.0
WH3_k127_8624412_1 Protein of unknown function (DUF1631) - - - 0.00000000000000000000000000000000000000000003523 171.0
WH3_k127_8664391_0 Bacterial protein of unknown function (DUF885) - - - 2.245e-254 794.0
WH3_k127_8664391_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000002611 63.0
WH3_k127_8674911_0 carboxylase K01968 - 6.4.1.4 4e-323 1013.0
WH3_k127_8674911_1 enoyl-CoA hydratase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 426.0
WH3_k127_8674911_2 Ferrous iron transport protein B K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 318.0
WH3_k127_8674911_4 ferrous iron transport protein K04758 - - 0.0000000000000000000000000001798 117.0
WH3_k127_8674911_5 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.000000000000000000000000007941 117.0
WH3_k127_8677565_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0 1231.0
WH3_k127_8677565_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1037.0
WH3_k127_8677565_2 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 441.0
WH3_k127_8677565_3 protein conserved in bacteria K09973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 425.0
WH3_k127_8677565_4 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 371.0
WH3_k127_8677565_5 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004422 254.0
WH3_k127_8677565_6 NAD- dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000001578 200.0
WH3_k127_8827480_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 7.2e-202 637.0
WH3_k127_8827480_1 Glutaredoxin K07390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 481.0
WH3_k127_8827480_2 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001913 259.0
WH3_k127_8827480_3 Lysophospholipase L1 and related esterases - - - 0.0000000000000000000000000000000000000000000000002887 178.0
WH3_k127_8831242_0 Histidine kinase - - - 7.536e-289 922.0
WH3_k127_8831242_1 Serine dehydratase K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 418.0
WH3_k127_8831242_2 thiol-disulfide isomerase and - - - 0.00000000000000000000000000005561 118.0
WH3_k127_8928637_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 531.0
WH3_k127_8928637_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006002 269.0
WH3_k127_8928637_2 cytochrome - - - 0.0000000000000000000000000000000000000000000000001791 183.0
WH3_k127_8928637_3 Cytochrome - - - 0.00000000000000000000000000000000000000000000443 177.0
WH3_k127_8959486_0 Terminase RNaseH-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 587.0
WH3_k127_8959486_1 - - - - 0.0009133 46.0
WH3_k127_8965111_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 325.0
WH3_k127_8965111_1 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000005446 254.0
WH3_k127_8965111_2 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000002678 156.0
WH3_k127_8970689_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 2.441e-261 810.0
WH3_k127_8970689_1 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 362.0
WH3_k127_8970689_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000001653 77.0
WH3_k127_9043136_0 beta-lactamase K01467 - 3.5.2.6 1.078e-208 659.0
WH3_k127_9043136_1 Peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 507.0
WH3_k127_9043136_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 321.0
WH3_k127_9081342_0 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 5.23e-208 651.0
WH3_k127_9081342_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 587.0
WH3_k127_9081342_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 342.0
WH3_k127_9081342_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002763 243.0
WH3_k127_9120163_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1165.0
WH3_k127_9120163_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 5.169e-212 666.0
WH3_k127_9120163_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 479.0
WH3_k127_9120163_3 acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 455.0
WH3_k127_9120163_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 450.0
WH3_k127_9120163_5 adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 317.0
WH3_k127_9120163_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 309.0
WH3_k127_9120163_7 hydroxylase K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003744 256.0
WH3_k127_9120163_8 protein affecting Mg2 Co2 transport K06195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008303 237.0
WH3_k127_9120163_9 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.6.1.41 0.0000000000000000002554 91.0
WH3_k127_913257_0 Histidine Phosphotransfer domain - - - 0.0 1052.0
WH3_k127_913257_1 chemotaxis protein K02660 - - 0.0000000000000000000000000000000000000000008397 158.0
WH3_k127_9154565_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 9.788e-245 767.0
WH3_k127_9154565_1 Sterol-binding protein K03690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 310.0
WH3_k127_9154565_2 3-beta hydroxysteroid dehydrogenase K22320 - 1.1.1.412 0.0000000000000000000000009172 103.0
WH3_k127_9166660_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 2.35e-313 961.0
WH3_k127_9166660_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 405.0
WH3_k127_9166660_2 one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high K00371 - 1.7.5.1 0.0000000000000000000000000000009209 121.0
WH3_k127_9212470_0 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 7.017e-240 746.0
WH3_k127_9212470_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 1.193e-219 685.0
WH3_k127_9225536_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 7.823e-312 969.0
WH3_k127_9225536_1 RNA polymerase sigma factor RpoH K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009986 270.0
WH3_k127_9230468_0 protein conserved in bacteria K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 612.0
WH3_k127_9230468_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 383.0
WH3_k127_9230468_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 337.0
WH3_k127_9230468_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000222 77.0
WH3_k127_9248342_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 413.0
WH3_k127_9248342_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 390.0
WH3_k127_9248342_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 343.0
WH3_k127_9248342_3 Putative adhesin - - - 0.00000000000000000000000000000000000000000006597 162.0
WH3_k127_9264217_0 Prokaryotic glutathione synthetase, ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 2.724e-249 774.0
WH3_k127_9264217_1 Mur ligase family, glutamate ligase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 601.0
WH3_k127_9264217_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 417.0
WH3_k127_9264217_3 haloacid dehalogenase K18697 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 398.0
WH3_k127_9264217_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007722 236.0
WH3_k127_9264217_5 Transcriptional regulator K10914 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0017076,GO:0019001,GO:0019219,GO:0019222,GO:0030551,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032561,GO:0035438,GO:0036094,GO:0043167,GO:0043168,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000001366 156.0
WH3_k127_9344316_0 belongs to the aldehyde dehydrogenase family - - - 5.631e-211 662.0
WH3_k127_9344316_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 608.0
WH3_k127_9370753_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 479.0
WH3_k127_9370753_1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 441.0
WH3_k127_9370753_2 - - - - 0.0000000000000000000000000000001115 125.0
WH3_k127_9458311_0 zinc metalloprotease K11749 - - 2.135e-195 638.0
WH3_k127_9458311_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 589.0
WH3_k127_9458311_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 469.0
WH3_k127_9458311_3 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 418.0
WH3_k127_9458311_4 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 406.0
WH3_k127_9458311_5 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000001037 219.0
WH3_k127_9489372_0 DNA-(Apurinic or apyrimidinic site) lyase K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 428.0
WH3_k127_9489372_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 353.0
WH3_k127_9489372_2 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009557 294.0
WH3_k127_9489372_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002224 258.0
WH3_k127_9502825_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 466.0
WH3_k127_9502825_1 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 413.0
WH3_k127_9502825_2 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 415.0
WH3_k127_9502825_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000003768 68.0
WH3_k127_9502825_4 heptosyltransferase K12982 - - 0.00001225 51.0
WH3_k127_9515066_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1127.0
WH3_k127_9515066_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 505.0
WH3_k127_9515066_2 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 293.0
WH3_k127_9515066_3 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000000000000000000001037 183.0
WH3_k127_9515066_4 succinate dehydrogenase K00242 - - 0.000000000000000000000000000000000000000000003275 173.0
WH3_k127_9515066_5 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000000000000000000000008391 153.0
WH3_k127_956128_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 451.0
WH3_k127_956128_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003524 254.0
WH3_k127_9579258_0 peptidase - - - 9.267e-319 984.0
WH3_k127_9609334_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 6.76e-259 804.0
WH3_k127_9609334_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.315e-197 624.0
WH3_k127_9609334_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000002816 203.0
WH3_k127_9642673_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 475.0
WH3_k127_9642673_1 protein conserved in bacteria K09793 - - 0.000000000000000000000000000000000000000000000000000000003594 205.0
WH3_k127_9642673_2 Lysine-specific metallo-endopeptidase - - - 0.00000000000000000000000000000000000000000000000000003135 187.0
WH3_k127_9642673_3 - - - - 0.000000000000000000000000000000000000000000000000003066 190.0
WH3_k127_9664856_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 584.0
WH3_k127_9664856_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 579.0
WH3_k127_9664856_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 469.0
WH3_k127_9664856_3 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 395.0
WH3_k127_9664856_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001232 253.0
WH3_k127_9664856_5 protein, YerC YecD - - - 0.0000000000000000000000000000000000009892 141.0
WH3_k127_9710926_0 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 602.0
WH3_k127_9710926_1 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 352.0
WH3_k127_9710926_2 assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 324.0
WH3_k127_9710926_3 pilus assembly protein pilp K02665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
WH3_k127_9710926_4 Type II secretory pathway, component HofQ K02666 - - 0.00000009362 55.0
WH3_k127_9720956_0 ferredoxin--nadp reductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 456.0
WH3_k127_9720956_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 302.0
WH3_k127_9720956_2 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 0.00000000000000000000000000000000000000000000000006266 181.0
WH3_k127_9720956_3 - - - - 0.00000000000000000000000000000008714 137.0
WH3_k127_9748473_0 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 8.74e-206 647.0
WH3_k127_9748473_1 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 493.0
WH3_k127_9748473_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18302 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 398.0
WH3_k127_9748473_3 AefR-like transcriptional repressor, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 326.0
WH3_k127_9748473_4 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 305.0
WH3_k127_9748473_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18303 - - 0.000000000000000000000000003162 111.0
WH3_k127_9748473_6 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.00000000000000001193 85.0
WH3_k127_9772580_0 3-beta hydroxysteroid dehydrogenase K22320 - 1.1.1.412 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 578.0
WH3_k127_9772580_1 AMP-binding enzyme K22319 - 6.1.3.1 0.000000000000000000000000000000000000000000000000000000000001211 220.0
WH3_k127_9794368_0 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 422.0
WH3_k127_9794368_1 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 396.0
WH3_k127_9799166_0 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 616.0
WH3_k127_9799166_1 polyphosphate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 422.0
WH3_k127_9799166_2 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001201 252.0
WH3_k127_9799166_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001528 237.0
WH3_k127_9799166_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000001256 171.0
WH3_k127_9799166_5 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000001197 120.0
WH3_k127_9799166_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000004059 63.0
WH3_k127_9906633_0 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 374.0
WH3_k127_9906633_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 312.0
WH3_k127_9906633_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000005704 153.0
WH3_k127_9921858_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 544.0
WH3_k127_9921858_1 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 312.0
WH3_k127_9921858_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 301.0
WH3_k127_9921858_3 membrane - - - 0.000000000000000000000000000000000000000000000000002761 196.0
WH3_k127_9921858_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000006058 165.0
WH3_k127_9921858_5 membrane protein terc - - - 0.00000000000001213 73.0
WH3_k127_9941371_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 371.0
WH3_k127_9941371_1 DNA processing protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 319.0
WH3_k127_9941371_2 Belongs to the Smg family K03747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008716 277.0
WH3_k127_9956125_0 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 557.0
WH3_k127_9956125_1 Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006317 275.0
WH3_k127_9956125_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000009486 216.0
WH3_k127_9956125_3 - - - - 0.00000000000000000000000000000000000000000000000359 180.0