Overview

ID MAG04180
Name WLSH1_bin.3
Sample SMP0109
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order UBA10834
Family UBA10834
Genus UBA9653
Species
Assembly information
Completeness (%) 67.65
Contamination (%) 0.46
GC content (%) 65.0
N50 (bp) 29,181
Genome size (bp) 1,468,671

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1276

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH1_k127_10044924_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 510.0
WLSH1_k127_10044924_1 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 422.0
WLSH1_k127_10044924_10 RIO1 family K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001744 223.0
WLSH1_k127_10044924_11 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000002377 220.0
WLSH1_k127_10044924_12 K homology RNA-binding domain K06961 - - 0.00000000000000000000000000000000000000000000000009259 190.0
WLSH1_k127_10044924_13 - - - - 0.00000000000000000000000000000000000000000003019 180.0
WLSH1_k127_10044924_14 PAC2 family K07159 - - 0.000000000000000000000000000000000000003561 149.0
WLSH1_k127_10044924_15 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000000000001016 147.0
WLSH1_k127_10044924_16 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000044 138.0
WLSH1_k127_10044924_17 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.0000000000000000000000000005564 116.0
WLSH1_k127_10044924_18 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000000002143 106.0
WLSH1_k127_10044924_19 - - - - 0.0000000000000000002097 98.0
WLSH1_k127_10044924_2 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 381.0
WLSH1_k127_10044924_20 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000002302 92.0
WLSH1_k127_10044924_21 - - - - 0.00000000415 68.0
WLSH1_k127_10044924_22 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00000645 52.0
WLSH1_k127_10044924_3 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 379.0
WLSH1_k127_10044924_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 333.0
WLSH1_k127_10044924_5 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 329.0
WLSH1_k127_10044924_6 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001247 270.0
WLSH1_k127_10044924_7 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 259.0
WLSH1_k127_10044924_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000003106 221.0
WLSH1_k127_10044924_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000009029 218.0
WLSH1_k127_10324225_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 315.0
WLSH1_k127_10324225_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000004625 186.0
WLSH1_k127_10324225_2 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.0000000000000000000000000000000000001914 149.0
WLSH1_k127_10324225_3 Met-10+ like-protein - - - 0.000000000000000000000000007939 115.0
WLSH1_k127_10324225_4 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000004106 105.0
WLSH1_k127_10324225_5 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.000000000000008662 78.0
WLSH1_k127_10324225_6 SCP-2 sterol transfer family - - - 0.0000000001082 72.0
WLSH1_k127_10324225_7 Tetratricopeptide TPR_2 repeat protein - - - 0.00006016 52.0
WLSH1_k127_10500434_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.258e-269 851.0
WLSH1_k127_10500434_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 621.0
WLSH1_k127_10500434_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 419.0
WLSH1_k127_10500434_3 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005644 284.0
WLSH1_k127_10500434_4 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002874 262.0
WLSH1_k127_10500434_5 Band 7 protein K07192 - - 0.00000000000000000000000000000000000000000000000002344 199.0
WLSH1_k127_10500434_6 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000005451 155.0
WLSH1_k127_10500434_7 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000008909 120.0
WLSH1_k127_10500434_8 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000768 89.0
WLSH1_k127_10500434_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000009307 87.0
WLSH1_k127_10683671_0 Cobalamin B12-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 543.0
WLSH1_k127_10683671_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 477.0
WLSH1_k127_10683671_10 - - - - 0.0000000000000000000000000000000000000000000000003746 182.0
WLSH1_k127_10683671_11 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.0000000000000000000000000000000000000000003368 179.0
WLSH1_k127_10683671_12 EamA-like transporter family - - - 0.00000000000000000000000000000000000007489 154.0
WLSH1_k127_10683671_13 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000002405 146.0
WLSH1_k127_10683671_14 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000003675 134.0
WLSH1_k127_10683671_15 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000009633 115.0
WLSH1_k127_10683671_16 Clostripain family - - - 0.0000000000000000000002136 111.0
WLSH1_k127_10683671_17 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000001793 90.0
WLSH1_k127_10683671_18 Belongs to the UPF0273 family - - - 0.0000000000003378 79.0
WLSH1_k127_10683671_19 - - - - 0.000000000005668 75.0
WLSH1_k127_10683671_2 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 482.0
WLSH1_k127_10683671_20 membrane - - - 0.00001502 55.0
WLSH1_k127_10683671_3 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K04940 - 1.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 406.0
WLSH1_k127_10683671_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 399.0
WLSH1_k127_10683671_5 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001848 292.0
WLSH1_k127_10683671_6 CO dehydrogenase acetyl-CoA synthase K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000001414 260.0
WLSH1_k127_10683671_7 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000001999 259.0
WLSH1_k127_10683671_8 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000001155 232.0
WLSH1_k127_10683671_9 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000803 191.0
WLSH1_k127_1157181_0 4Fe-4S single cluster domain K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 575.0
WLSH1_k127_1157181_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 565.0
WLSH1_k127_1157181_10 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 293.0
WLSH1_k127_1157181_11 GtrA-like protein K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004788 295.0
WLSH1_k127_1157181_12 glutathione-regulated potassium exporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005755 289.0
WLSH1_k127_1157181_13 Diphthamide K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000007128 270.0
WLSH1_k127_1157181_14 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001112 272.0
WLSH1_k127_1157181_15 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000397 263.0
WLSH1_k127_1157181_16 Archaeal transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000000000184 226.0
WLSH1_k127_1157181_17 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000001063 232.0
WLSH1_k127_1157181_18 Lamin Tail Domain - - - 0.00000000000000000000000000000000000000000000000000000005358 226.0
WLSH1_k127_1157181_19 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000005247 208.0
WLSH1_k127_1157181_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 514.0
WLSH1_k127_1157181_20 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001367 200.0
WLSH1_k127_1157181_21 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000005668 195.0
WLSH1_k127_1157181_22 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000006273 191.0
WLSH1_k127_1157181_23 Glycosyltransferase Family 4 K13677 - 2.4.1.208 0.000000000000000000000000000000000000000000000002891 188.0
WLSH1_k127_1157181_24 methyltransferase activity - - - 0.00000000000000000000000000000000000000008257 160.0
WLSH1_k127_1157181_25 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000002127 168.0
WLSH1_k127_1157181_26 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000002065 162.0
WLSH1_k127_1157181_27 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000001604 160.0
WLSH1_k127_1157181_28 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000134 138.0
WLSH1_k127_1157181_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 490.0
WLSH1_k127_1157181_30 PFAM polysaccharide biosynthesis protein - - - 0.00000000000000000000000002048 125.0
WLSH1_k127_1157181_31 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000005834 121.0
WLSH1_k127_1157181_32 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000001704 113.0
WLSH1_k127_1157181_33 - - - - 0.00000000000000000001647 104.0
WLSH1_k127_1157181_34 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000002529 88.0
WLSH1_k127_1157181_35 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000004 84.0
WLSH1_k127_1157181_36 YjbR - - - 0.00000000000000004168 86.0
WLSH1_k127_1157181_37 - - - - 0.000000000379 63.0
WLSH1_k127_1157181_38 CRS1_YhbY K07574 - - 0.00000002635 58.0
WLSH1_k127_1157181_39 Peptidase, S9A B C family, catalytic domain protein - - - 0.0000008574 60.0
WLSH1_k127_1157181_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 428.0
WLSH1_k127_1157181_40 ACT domain protein - - - 0.000002213 55.0
WLSH1_k127_1157181_41 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000005239 59.0
WLSH1_k127_1157181_42 sequence-specific DNA binding - - - 0.00000813 57.0
WLSH1_k127_1157181_43 acetyltransferase - - - 0.0001375 53.0
WLSH1_k127_1157181_44 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0008962 48.0
WLSH1_k127_1157181_5 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 418.0
WLSH1_k127_1157181_6 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 387.0
WLSH1_k127_1157181_7 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 380.0
WLSH1_k127_1157181_8 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 378.0
WLSH1_k127_1157181_9 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 371.0
WLSH1_k127_1333251_0 CobW/HypB/UreG, nucleotide-binding domain - - - 5.393e-195 617.0
WLSH1_k127_1333251_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 461.0
WLSH1_k127_1333251_10 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000003367 258.0
WLSH1_k127_1333251_11 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001332 269.0
WLSH1_k127_1333251_12 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000002142 250.0
WLSH1_k127_1333251_13 nitrogen compound transport K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000003877 240.0
WLSH1_k127_1333251_14 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000000000000001361 238.0
WLSH1_k127_1333251_15 Putative RNA methylase family UPF0020 K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000009261 193.0
WLSH1_k127_1333251_16 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.00000000000000000000000000000000000000000000000002337 196.0
WLSH1_k127_1333251_17 amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000813 186.0
WLSH1_k127_1333251_18 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000002421 176.0
WLSH1_k127_1333251_19 PFAM GvpD gas vesicle - - - 0.000000000000000000000000000000000000000000003158 183.0
WLSH1_k127_1333251_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 456.0
WLSH1_k127_1333251_20 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000007297 158.0
WLSH1_k127_1333251_21 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000001545 162.0
WLSH1_k127_1333251_22 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000001267 108.0
WLSH1_k127_1333251_23 - - - - 0.0000000000000000000004586 100.0
WLSH1_k127_1333251_24 transcriptional regulators - - - 0.0000000000000006306 82.0
WLSH1_k127_1333251_25 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000000000000342 71.0
WLSH1_k127_1333251_26 pectinesterase activity K01728 - 4.2.2.2 0.0000000002188 74.0
WLSH1_k127_1333251_27 4Fe-4S dicluster domain - - - 0.000000005038 68.0
WLSH1_k127_1333251_28 - - - - 0.00000003717 64.0
WLSH1_k127_1333251_29 domain, Protein - - - 0.000001545 61.0
WLSH1_k127_1333251_3 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 450.0
WLSH1_k127_1333251_30 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000374 53.0
WLSH1_k127_1333251_31 protein conserved in archaea - - - 0.00001072 59.0
WLSH1_k127_1333251_32 Major Facilitator Superfamily K08222 - - 0.0000289 56.0
WLSH1_k127_1333251_33 zinc-ribbon domain - - - 0.00004021 52.0
WLSH1_k127_1333251_34 zinc-ribbon domain - - - 0.00005348 53.0
WLSH1_k127_1333251_4 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 407.0
WLSH1_k127_1333251_5 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 402.0
WLSH1_k127_1333251_6 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 366.0
WLSH1_k127_1333251_7 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 351.0
WLSH1_k127_1333251_8 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 321.0
WLSH1_k127_1333251_9 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 305.0
WLSH1_k127_1473424_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 559.0
WLSH1_k127_1473424_1 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 329.0
WLSH1_k127_1473424_2 PFAM ApbE family K09740 - - 0.00000000000000000000485 100.0
WLSH1_k127_1473424_3 - - - - 0.000006563 57.0
WLSH1_k127_1479944_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1403.0
WLSH1_k127_1479944_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.619e-221 711.0
WLSH1_k127_1479944_10 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 407.0
WLSH1_k127_1479944_11 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 420.0
WLSH1_k127_1479944_12 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 396.0
WLSH1_k127_1479944_13 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 386.0
WLSH1_k127_1479944_14 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 378.0
WLSH1_k127_1479944_15 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 381.0
WLSH1_k127_1479944_16 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 374.0
WLSH1_k127_1479944_17 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 360.0
WLSH1_k127_1479944_18 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 361.0
WLSH1_k127_1479944_19 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 333.0
WLSH1_k127_1479944_2 AAA domain K01338 - 3.4.21.53 4.222e-202 641.0
WLSH1_k127_1479944_20 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 318.0
WLSH1_k127_1479944_21 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 318.0
WLSH1_k127_1479944_22 PP-loop family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 308.0
WLSH1_k127_1479944_23 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 309.0
WLSH1_k127_1479944_24 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 291.0
WLSH1_k127_1479944_25 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000003765 253.0
WLSH1_k127_1479944_26 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000001051 265.0
WLSH1_k127_1479944_27 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000003375 246.0
WLSH1_k127_1479944_28 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000615 243.0
WLSH1_k127_1479944_29 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000003284 241.0
WLSH1_k127_1479944_3 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 576.0
WLSH1_k127_1479944_30 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000218 220.0
WLSH1_k127_1479944_31 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000164 218.0
WLSH1_k127_1479944_32 - - - - 0.000000000000000000000000000000000000000000000000000000001408 210.0
WLSH1_k127_1479944_33 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000006126 211.0
WLSH1_k127_1479944_34 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000001501 192.0
WLSH1_k127_1479944_35 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000002147 187.0
WLSH1_k127_1479944_36 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.00000000000000000000000000000000000000000000000003782 201.0
WLSH1_k127_1479944_37 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.0000000000000000000000000000000000000000000000003736 194.0
WLSH1_k127_1479944_38 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000003215 188.0
WLSH1_k127_1479944_39 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000102 181.0
WLSH1_k127_1479944_4 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 514.0
WLSH1_k127_1479944_40 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000001466 171.0
WLSH1_k127_1479944_41 LysE type translocator - - - 0.000000000000000000000000000000000000000000001021 173.0
WLSH1_k127_1479944_42 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000000133 169.0
WLSH1_k127_1479944_43 Archaeal holliday junction resolvase (hjc) - - - 0.00000000000000000000000000000000000000000000199 172.0
WLSH1_k127_1479944_44 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000000000000000000000000005105 183.0
WLSH1_k127_1479944_45 shikimate kinase activity K00891 - 2.7.1.71 0.000000000000000000000000000000000000000003961 171.0
WLSH1_k127_1479944_46 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000000000001385 156.0
WLSH1_k127_1479944_47 Domains REC, HisKA, HATPase_c - - - 0.00000000000000000000000000000000000000002398 174.0
WLSH1_k127_1479944_48 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000000004011 151.0
WLSH1_k127_1479944_49 PFAM Pyruvate K00177 - 1.2.7.3 0.0000000000000000000000000000000000001044 148.0
WLSH1_k127_1479944_5 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 493.0
WLSH1_k127_1479944_50 Phosphatidylserine decarboxylase K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000001302 142.0
WLSH1_k127_1479944_51 PFAM NIL domain - - - 0.00000000000000000000000000000006734 129.0
WLSH1_k127_1479944_52 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000004326 138.0
WLSH1_k127_1479944_53 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000001985 110.0
WLSH1_k127_1479944_54 YHS domain - - - 0.0000000000000000005422 86.0
WLSH1_k127_1479944_55 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000017 84.0
WLSH1_k127_1479944_56 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000001402 90.0
WLSH1_k127_1479944_57 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.0000000000000008821 89.0
WLSH1_k127_1479944_58 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000005292 79.0
WLSH1_k127_1479944_59 Transcriptional - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000006341 83.0
WLSH1_k127_1479944_6 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 488.0
WLSH1_k127_1479944_60 COG1522 Transcriptional regulators - - - 0.0000000000005754 80.0
WLSH1_k127_1479944_61 - - - - 0.00000001694 64.0
WLSH1_k127_1479944_62 Sulfur transfer protein involved in thiamine biosynthesis K03154,K21947 GO:0003674,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031386,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070647,GO:0071704,GO:1901564 2.8.1.15 0.00000004076 57.0
WLSH1_k127_1479944_63 Belongs to the UPF0280 family K09740 - - 0.0000001558 56.0
WLSH1_k127_1479944_64 PFAM Prenyltransferase and squalene oxidase repeat K06045 - 4.2.1.129,5.4.99.17 0.00004417 56.0
WLSH1_k127_1479944_7 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 470.0
WLSH1_k127_1479944_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 468.0
WLSH1_k127_1479944_9 Toprim domain K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 421.0
WLSH1_k127_1589256_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 370.0
WLSH1_k127_1589256_1 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001594 265.0
WLSH1_k127_1589256_2 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000003985 241.0
WLSH1_k127_1589256_3 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.000000000000000000000001035 116.0
WLSH1_k127_1679284_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.939e-264 850.0
WLSH1_k127_1679284_1 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 520.0
WLSH1_k127_1679284_10 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000000007543 242.0
WLSH1_k127_1679284_11 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004328 251.0
WLSH1_k127_1679284_12 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.00000000000000000000000000000000000000000000000000000000006996 210.0
WLSH1_k127_1679284_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000002089 184.0
WLSH1_k127_1679284_14 VIT family - - - 0.0000000000000000000000000000000000000002939 158.0
WLSH1_k127_1679284_15 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000005654 155.0
WLSH1_k127_1679284_16 Peptidase family M28 K01439 - 3.5.1.18 0.00000000000000000000000000000000000008469 163.0
WLSH1_k127_1679284_17 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000001964 130.0
WLSH1_k127_1679284_18 - - - - 0.0000000000000000000000000000004217 134.0
WLSH1_k127_1679284_19 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000009674 132.0
WLSH1_k127_1679284_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 466.0
WLSH1_k127_1679284_21 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000000000625 108.0
WLSH1_k127_1679284_22 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000008426 109.0
WLSH1_k127_1679284_23 Lrp/AsnC ligand binding domain - - - 0.000000000000000000001109 98.0
WLSH1_k127_1679284_24 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000008637 99.0
WLSH1_k127_1679284_25 - - - - 0.000000000000004366 76.0
WLSH1_k127_1679284_26 Domain of unknown function (DUF296) K06934 - - 0.00000000000001023 79.0
WLSH1_k127_1679284_27 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.0000000000000221 79.0
WLSH1_k127_1679284_28 Major facilitator superfamily - - - 0.00000000000002266 85.0
WLSH1_k127_1679284_29 - - - - 0.000000000001018 71.0
WLSH1_k127_1679284_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 439.0
WLSH1_k127_1679284_30 - - - - 0.0000000003016 65.0
WLSH1_k127_1679284_31 Periplasmic copper-binding protein (NosD) - - - 0.000000001334 70.0
WLSH1_k127_1679284_32 Protein of unknown function (DUF998) - - - 0.000000264 60.0
WLSH1_k127_1679284_33 Protein of unknown function DUF131 - - - 0.00001112 54.0
WLSH1_k127_1679284_34 acid phosphatase activity - - - 0.0003521 51.0
WLSH1_k127_1679284_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 328.0
WLSH1_k127_1679284_5 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001804 288.0
WLSH1_k127_1679284_6 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002321 291.0
WLSH1_k127_1679284_7 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005118 282.0
WLSH1_k127_1679284_8 PFAM sodium calcium exchanger K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001164 269.0
WLSH1_k127_1679284_9 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000005408 239.0
WLSH1_k127_1752187_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 596.0
WLSH1_k127_1752187_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 509.0
WLSH1_k127_1752187_10 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000001135 201.0
WLSH1_k127_1752187_11 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000001872 194.0
WLSH1_k127_1752187_12 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000003116 202.0
WLSH1_k127_1752187_13 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000002207 145.0
WLSH1_k127_1752187_14 domain, Protein K00077,K01179,K07260,K13735 - 1.1.1.169,3.2.1.4,3.4.17.14 0.000000000000000000000000000000000004017 157.0
WLSH1_k127_1752187_15 4Fe-4S binding domain - - - 0.000000000000000000000000000000000247 138.0
WLSH1_k127_1752187_16 Cobalt transport protein K16785 - - 0.000000000000000000000000000000006203 145.0
WLSH1_k127_1752187_17 Flavodoxin - - - 0.000000000000000000000000000007061 132.0
WLSH1_k127_1752187_18 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000000000000000000000001041 109.0
WLSH1_k127_1752187_19 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000002973 97.0
WLSH1_k127_1752187_2 Arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 387.0
WLSH1_k127_1752187_20 - - - - 0.00000000000000000005153 100.0
WLSH1_k127_1752187_21 Roadblock LC7 family protein K07131 - - 0.0000000000000000001358 92.0
WLSH1_k127_1752187_22 serine threonine protein kinase - - - 0.0000000000000000006012 96.0
WLSH1_k127_1752187_23 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000007535 100.0
WLSH1_k127_1752187_24 binds to the 23S rRNA K02922 - - 0.00000000000000000381 84.0
WLSH1_k127_1752187_25 - - - - 0.0000000000000007623 86.0
WLSH1_k127_1752187_26 - - - - 0.00000001513 61.0
WLSH1_k127_1752187_27 transcriptional K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000005544 59.0
WLSH1_k127_1752187_3 ABC transporter K00400,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 359.0
WLSH1_k127_1752187_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 351.0
WLSH1_k127_1752187_5 Peptidase family S51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 312.0
WLSH1_k127_1752187_6 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000007124 237.0
WLSH1_k127_1752187_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000002076 220.0
WLSH1_k127_1752187_8 COG2041 Sulfite oxidase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000104 223.0
WLSH1_k127_1752187_9 RibD C-terminal domain K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000005651 194.0
WLSH1_k127_1918495_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.0 1166.0
WLSH1_k127_1918495_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 4.541e-254 794.0
WLSH1_k127_1918495_2 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 314.0
WLSH1_k127_1918495_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000228 270.0
WLSH1_k127_1918495_4 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000002834 247.0
WLSH1_k127_1918495_5 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007039 207.0
WLSH1_k127_1918495_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000003021 209.0
WLSH1_k127_1918495_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000007817 187.0
WLSH1_k127_1918495_8 cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000315 68.0
WLSH1_k127_1918495_9 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000004917 64.0
WLSH1_k127_1984102_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1038.0
WLSH1_k127_1984102_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 295.0
WLSH1_k127_1984102_2 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000002736 243.0
WLSH1_k127_1984102_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000002544 236.0
WLSH1_k127_1984102_4 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000001089 164.0
WLSH1_k127_1984102_5 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.0000000000000000000000000000000000002232 145.0
WLSH1_k127_1984102_6 Protein of unknown function (DUF1616) - - - 0.0000000000000000000003027 103.0
WLSH1_k127_1984102_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000006964 54.0
WLSH1_k127_2067819_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.306e-304 955.0
WLSH1_k127_2067819_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 4.243e-212 674.0
WLSH1_k127_2067819_10 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000000000000000000000000002744 222.0
WLSH1_k127_2067819_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000001963 201.0
WLSH1_k127_2067819_12 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000001059 198.0
WLSH1_k127_2067819_13 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000005912 183.0
WLSH1_k127_2067819_14 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000001592 162.0
WLSH1_k127_2067819_15 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000003859 173.0
WLSH1_k127_2067819_16 - - - - 0.000000000000000000000000000000000000000003037 160.0
WLSH1_k127_2067819_17 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000001473 158.0
WLSH1_k127_2067819_18 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000004854 157.0
WLSH1_k127_2067819_19 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000009584 149.0
WLSH1_k127_2067819_2 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 542.0
WLSH1_k127_2067819_20 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000004902 134.0
WLSH1_k127_2067819_21 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.00000000000000000000000000002266 117.0
WLSH1_k127_2067819_22 Thiamine-binding protein - - - 0.0000000000000000000000008555 108.0
WLSH1_k127_2067819_23 PFAM Forkhead-associated protein - - - 0.00000000000000000000000466 118.0
WLSH1_k127_2067819_24 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000003639 95.0
WLSH1_k127_2067819_25 Papain family cysteine protease - - - 0.00000000000001361 88.0
WLSH1_k127_2067819_26 spore germination - - - 0.00000000000008777 82.0
WLSH1_k127_2067819_27 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000002584 82.0
WLSH1_k127_2067819_28 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000147 54.0
WLSH1_k127_2067819_3 HELICc2 K03722,K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 491.0
WLSH1_k127_2067819_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 412.0
WLSH1_k127_2067819_5 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 362.0
WLSH1_k127_2067819_6 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 298.0
WLSH1_k127_2067819_7 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003493 292.0
WLSH1_k127_2067819_8 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002791 268.0
WLSH1_k127_2067819_9 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000004259 261.0
WLSH1_k127_2503062_0 GXGXG motif - - - 1.365e-283 900.0
WLSH1_k127_2503062_1 Glutamate synthase - - - 9.087e-197 626.0
WLSH1_k127_2503062_10 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 410.0
WLSH1_k127_2503062_11 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 382.0
WLSH1_k127_2503062_12 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 365.0
WLSH1_k127_2503062_13 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 346.0
WLSH1_k127_2503062_14 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 330.0
WLSH1_k127_2503062_15 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 315.0
WLSH1_k127_2503062_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 314.0
WLSH1_k127_2503062_17 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 295.0
WLSH1_k127_2503062_18 Bacterial Na+/H+ antiporter B (NhaB) K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001247 285.0
WLSH1_k127_2503062_19 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005728 235.0
WLSH1_k127_2503062_2 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 579.0
WLSH1_k127_2503062_20 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000005751 231.0
WLSH1_k127_2503062_21 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000002114 220.0
WLSH1_k127_2503062_22 GAF domain - - - 0.000000000000000000000000000000000000000000000009424 192.0
WLSH1_k127_2503062_23 PIN domain - - - 0.00000000000000000000000000000000000000000000891 183.0
WLSH1_k127_2503062_24 LacY proton/sugar symporter - - - 0.0000000000000000000000000000001845 138.0
WLSH1_k127_2503062_25 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000005543 130.0
WLSH1_k127_2503062_26 OsmC-like protein - - - 0.000000000000000000000000000004923 127.0
WLSH1_k127_2503062_27 - - - - 0.0000000000000000000000000001484 124.0
WLSH1_k127_2503062_29 - - - - 0.000000000000000000000000315 111.0
WLSH1_k127_2503062_3 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 520.0
WLSH1_k127_2503062_30 PFAM Glutaredoxin K06191 - - 0.000000000000000007957 85.0
WLSH1_k127_2503062_31 - - - - 0.0000000000000001971 82.0
WLSH1_k127_2503062_32 - - - - 0.000000000002171 78.0
WLSH1_k127_2503062_33 SpoVT / AbrB like domain - - - 0.000000000002988 70.0
WLSH1_k127_2503062_34 4Fe-4S binding domain - - - 0.00000000006374 66.0
WLSH1_k127_2503062_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 514.0
WLSH1_k127_2503062_5 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 509.0
WLSH1_k127_2503062_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 476.0
WLSH1_k127_2503062_7 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 447.0
WLSH1_k127_2503062_8 histidyl-tRNA aminoacylation K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 446.0
WLSH1_k127_2503062_9 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 415.0
WLSH1_k127_2517308_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 436.0
WLSH1_k127_2517308_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 346.0
WLSH1_k127_2517308_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000005956 141.0
WLSH1_k127_2517386_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1489.0
WLSH1_k127_2517386_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.427e-272 861.0
WLSH1_k127_2517386_10 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 329.0
WLSH1_k127_2517386_11 Rad51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 325.0
WLSH1_k127_2517386_12 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 293.0
WLSH1_k127_2517386_13 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000007957 256.0
WLSH1_k127_2517386_14 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001897 249.0
WLSH1_k127_2517386_15 ATPase component of various ABC-type transport systems with duplicated ATPase domain K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000002395 247.0
WLSH1_k127_2517386_16 ATP-binding protein K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000001593 237.0
WLSH1_k127_2517386_17 PFAM Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000002513 216.0
WLSH1_k127_2517386_18 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000003576 222.0
WLSH1_k127_2517386_19 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000699 223.0
WLSH1_k127_2517386_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.315e-264 836.0
WLSH1_k127_2517386_20 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000005055 198.0
WLSH1_k127_2517386_21 Double zinc ribbon - - - 0.0000000000000000000000000000000000000000000000003181 204.0
WLSH1_k127_2517386_22 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000008936 183.0
WLSH1_k127_2517386_23 NMD3 family K07562 - - 0.00000000000000000000000000000000000000000000004415 182.0
WLSH1_k127_2517386_24 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000007074 172.0
WLSH1_k127_2517386_25 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000004811 151.0
WLSH1_k127_2517386_26 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000009103 153.0
WLSH1_k127_2517386_27 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000005954 110.0
WLSH1_k127_2517386_28 DnaB-like helicase C terminal domain - - - 0.0000000000000000000003521 107.0
WLSH1_k127_2517386_29 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000002466 106.0
WLSH1_k127_2517386_3 MCM OB domain K10726 - - 1.326e-216 693.0
WLSH1_k127_2517386_30 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000009381 78.0
WLSH1_k127_2517386_31 Belongs to the peptidase S8 family - - - 0.00000000003289 76.0
WLSH1_k127_2517386_32 RDD family - - - 0.000002188 56.0
WLSH1_k127_2517386_33 Double zinc ribbon - - - 0.000008424 59.0
WLSH1_k127_2517386_34 - - - - 0.00002121 55.0
WLSH1_k127_2517386_35 Pfam:DUF1628 - - - 0.00003299 53.0
WLSH1_k127_2517386_36 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.0002242 50.0
WLSH1_k127_2517386_37 PKD domain - - - 0.0002745 52.0
WLSH1_k127_2517386_4 Type II/IV secretion system protein K07332 - - 3.963e-202 635.0
WLSH1_k127_2517386_5 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 499.0
WLSH1_k127_2517386_6 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 492.0
WLSH1_k127_2517386_7 FAD binding domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 371.0
WLSH1_k127_2517386_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 339.0
WLSH1_k127_2517386_9 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 327.0
WLSH1_k127_2792365_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 411.0
WLSH1_k127_2792365_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 401.0
WLSH1_k127_2792365_10 response to antibiotic - - - 0.0005611 51.0
WLSH1_k127_2792365_11 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0008285 47.0
WLSH1_k127_2792365_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 323.0
WLSH1_k127_2792365_3 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 323.0
WLSH1_k127_2792365_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 312.0
WLSH1_k127_2792365_5 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 308.0
WLSH1_k127_2792365_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000295 267.0
WLSH1_k127_2792365_7 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000001105 190.0
WLSH1_k127_2792365_8 ICC-like phosphoesterases K06953 - - 0.0000000000000000000000000000000000000000000000005254 186.0
WLSH1_k127_2792365_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000001446 183.0
WLSH1_k127_3017633_0 DNA polymerase type-B family K02319 - 2.7.7.7 8.345e-262 835.0
WLSH1_k127_3017633_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 488.0
WLSH1_k127_3017633_10 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000008337 79.0
WLSH1_k127_3017633_2 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 466.0
WLSH1_k127_3017633_3 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 334.0
WLSH1_k127_3017633_4 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003036 255.0
WLSH1_k127_3017633_5 Helix-hairpin-helix motif K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000000002289 237.0
WLSH1_k127_3017633_6 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000004545 226.0
WLSH1_k127_3017633_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000003346 175.0
WLSH1_k127_3017633_8 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000001314 182.0
WLSH1_k127_3017633_9 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000007342 112.0
WLSH1_k127_3224146_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 540.0
WLSH1_k127_3224146_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 533.0
WLSH1_k127_3224146_10 PFAM Forkhead-associated protein - - - 0.0000000000000000000000002086 120.0
WLSH1_k127_3224146_11 - - - - 0.0000000000000000008437 100.0
WLSH1_k127_3224146_12 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000007457 85.0
WLSH1_k127_3224146_13 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000003333 83.0
WLSH1_k127_3224146_14 Sulfite exporter TauE/SafE K07090 - - 0.000000000002124 77.0
WLSH1_k127_3224146_15 PKD domain - - - 0.00000000005008 77.0
WLSH1_k127_3224146_16 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.00000003849 66.0
WLSH1_k127_3224146_17 Double zinc ribbon - - - 0.000001263 58.0
WLSH1_k127_3224146_18 Dinitrogenase iron-molybdenum cofactor - - - 0.000004679 56.0
WLSH1_k127_3224146_19 PFAM Flavodoxin K03809 - 1.6.5.2 0.000008002 54.0
WLSH1_k127_3224146_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 389.0
WLSH1_k127_3224146_4 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 306.0
WLSH1_k127_3224146_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003022 285.0
WLSH1_k127_3224146_6 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000000000000000000000000000000000000000000004143 189.0
WLSH1_k127_3224146_7 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000006281 177.0
WLSH1_k127_3224146_8 PFAM amidinotransferase K01478,K01482 - 3.5.3.18,3.5.3.6 0.000000000000000000000000000000000000000000003578 179.0
WLSH1_k127_3224146_9 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000002868 150.0
WLSH1_k127_3350140_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 517.0
WLSH1_k127_3350140_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 462.0
WLSH1_k127_3350140_10 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000000000000000000000000000000000000000007995 179.0
WLSH1_k127_3350140_11 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.00000000000000000000000000000000000000489 154.0
WLSH1_k127_3350140_12 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.0000000000000000000000000000000000004014 162.0
WLSH1_k127_3350140_13 Rubrerythrin - - - 0.0000000002645 68.0
WLSH1_k127_3350140_2 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 416.0
WLSH1_k127_3350140_3 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 385.0
WLSH1_k127_3350140_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 359.0
WLSH1_k127_3350140_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 328.0
WLSH1_k127_3350140_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002994 273.0
WLSH1_k127_3350140_7 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000002298 258.0
WLSH1_k127_3350140_8 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004979 261.0
WLSH1_k127_3350140_9 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000007803 240.0
WLSH1_k127_3385507_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 496.0
WLSH1_k127_3385507_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 472.0
WLSH1_k127_3385507_10 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 325.0
WLSH1_k127_3385507_11 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 325.0
WLSH1_k127_3385507_12 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 333.0
WLSH1_k127_3385507_13 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 299.0
WLSH1_k127_3385507_14 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000056 279.0
WLSH1_k127_3385507_15 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000003973 243.0
WLSH1_k127_3385507_16 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000004871 238.0
WLSH1_k127_3385507_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000006663 241.0
WLSH1_k127_3385507_18 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000002536 231.0
WLSH1_k127_3385507_19 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000002536 221.0
WLSH1_k127_3385507_2 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 426.0
WLSH1_k127_3385507_20 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000002013 224.0
WLSH1_k127_3385507_21 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000005677 211.0
WLSH1_k127_3385507_22 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000164 202.0
WLSH1_k127_3385507_23 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000003484 186.0
WLSH1_k127_3385507_24 SIS domain K08094 - 5.3.1.27 0.00000000000000000000000000000000000000000000007616 175.0
WLSH1_k127_3385507_25 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000002476 186.0
WLSH1_k127_3385507_26 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000007585 170.0
WLSH1_k127_3385507_27 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000385 174.0
WLSH1_k127_3385507_28 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000476 183.0
WLSH1_k127_3385507_29 PFAM UBA THIF-type NAD FAD binding protein - - - 0.0000000000000000000000000000000000000002202 160.0
WLSH1_k127_3385507_3 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 383.0
WLSH1_k127_3385507_30 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000007728 149.0
WLSH1_k127_3385507_31 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000001668 152.0
WLSH1_k127_3385507_32 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002866 132.0
WLSH1_k127_3385507_33 - - - - 0.0000000000000000000000000002456 126.0
WLSH1_k127_3385507_34 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000001919 111.0
WLSH1_k127_3385507_35 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000003046 108.0
WLSH1_k127_3385507_36 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.000000000000000000000004135 113.0
WLSH1_k127_3385507_37 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000001166 100.0
WLSH1_k127_3385507_38 Tetratricopeptide repeats - - - 0.0000000000002706 84.0
WLSH1_k127_3385507_39 to Saccharomyces cerevisiae RPN11 (YFR004W) K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.000000000001807 77.0
WLSH1_k127_3385507_4 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 383.0
WLSH1_k127_3385507_40 histone ubiquitination K10573 GO:0000151,GO:0000209,GO:0000228,GO:0000785,GO:0000790,GO:0000792,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006325,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016043,GO:0016567,GO:0016569,GO:0016570,GO:0016574,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0030163,GO:0031371,GO:0031625,GO:0031974,GO:0031981,GO:0032446,GO:0032991,GO:0033503,GO:0033554,GO:0034641,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051603,GO:0051716,GO:0061630,GO:0061659,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234 2.3.2.23 0.00000000005776 72.0
WLSH1_k127_3385507_5 Major facilitator Superfamily K08217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 374.0
WLSH1_k127_3385507_6 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 349.0
WLSH1_k127_3385507_7 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 364.0
WLSH1_k127_3385507_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 349.0
WLSH1_k127_3385507_9 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 333.0
WLSH1_k127_3622015_0 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000008823 197.0
WLSH1_k127_3622015_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000000001523 190.0
WLSH1_k127_3633948_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 4.037e-288 909.0
WLSH1_k127_3633948_1 Aminotransferase class-III K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 437.0
WLSH1_k127_3633948_10 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000004867 170.0
WLSH1_k127_3633948_11 Transcriptional regulator, ArsR family - - - 0.00000000000000000000000000000000000009528 150.0
WLSH1_k127_3633948_12 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000001025 142.0
WLSH1_k127_3633948_13 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000007024 146.0
WLSH1_k127_3633948_14 - - - - 0.000000000000000001281 100.0
WLSH1_k127_3633948_15 Transcriptional regulator K07730 - - 0.00000000000000003621 91.0
WLSH1_k127_3633948_16 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000003745 97.0
WLSH1_k127_3633948_17 Di-glucose binding within endoplasmic reticulum - - - 0.00000000000001479 87.0
WLSH1_k127_3633948_18 cell wall binding repeat 2 - - - 0.0000000001449 77.0
WLSH1_k127_3633948_19 BON domain - - - 0.0001739 50.0
WLSH1_k127_3633948_2 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 351.0
WLSH1_k127_3633948_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 308.0
WLSH1_k127_3633948_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 291.0
WLSH1_k127_3633948_5 Clostripain family - - - 0.000000000000000000000000000000000000000000000000000000000000000008913 259.0
WLSH1_k127_3633948_6 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000001964 230.0
WLSH1_k127_3633948_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000006037 230.0
WLSH1_k127_3633948_8 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000001455 212.0
WLSH1_k127_3633948_9 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000007791 182.0
WLSH1_k127_4008576_0 Aminotransferase class-III K00823,K03918,K20428 - 2.6.1.19,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 426.0
WLSH1_k127_4008576_1 PFAM elongation factor Tu domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 379.0
WLSH1_k127_4008576_10 hmm pf03415 K08587 - 3.4.22.8 0.0000000000000000000000000113 124.0
WLSH1_k127_4008576_11 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000002657 115.0
WLSH1_k127_4008576_12 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000002322 106.0
WLSH1_k127_4008576_13 Clostripain family - - - 0.00000000000000000002924 104.0
WLSH1_k127_4008576_14 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000102 81.0
WLSH1_k127_4008576_15 ABC-2 family transporter protein K01992 - - 0.00000000000007071 84.0
WLSH1_k127_4008576_16 Predicted membrane protein (DUF2085) - - - 0.000000000155 70.0
WLSH1_k127_4008576_17 - - - - 0.00000000248 62.0
WLSH1_k127_4008576_18 - K01992 - - 0.000000005709 66.0
WLSH1_k127_4008576_19 Esterase PHB depolymerase - - - 0.0000004417 61.0
WLSH1_k127_4008576_2 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 311.0
WLSH1_k127_4008576_20 PFAM amino acid-binding ACT domain protein - - - 0.0000005062 57.0
WLSH1_k127_4008576_21 - - - - 0.0000005516 62.0
WLSH1_k127_4008576_22 Predicted RNA-binding protein - - - 0.0002677 46.0
WLSH1_k127_4008576_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 311.0
WLSH1_k127_4008576_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 295.0
WLSH1_k127_4008576_5 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002968 283.0
WLSH1_k127_4008576_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004641 252.0
WLSH1_k127_4008576_7 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000001716 235.0
WLSH1_k127_4008576_8 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000000004155 222.0
WLSH1_k127_4008576_9 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000008237 198.0
WLSH1_k127_404069_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 4.812e-231 728.0
WLSH1_k127_404069_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 6.535e-226 722.0
WLSH1_k127_404069_10 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000595 193.0
WLSH1_k127_404069_11 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000005954 177.0
WLSH1_k127_404069_12 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000000000002069 173.0
WLSH1_k127_404069_13 AAA domain - - - 0.000000000000000000000000000000000000000002413 165.0
WLSH1_k127_404069_14 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000002521 169.0
WLSH1_k127_404069_15 Sodium hydrogen exchanger K11105 - - 0.0000000000000000000000000000000000001439 163.0
WLSH1_k127_404069_16 DsrE/DsrF-like family K07235 - - 0.000000000000000000000000002058 115.0
WLSH1_k127_404069_17 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000002573 112.0
WLSH1_k127_404069_18 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000000005479 114.0
WLSH1_k127_404069_19 ABC-2 family transporter protein K01992 - - 0.000000000000000000000006593 116.0
WLSH1_k127_404069_2 aspartate carbamoyltransferase activity K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 405.0
WLSH1_k127_404069_20 4Fe-4S dicluster domain - - - 0.00000000000000000002734 94.0
WLSH1_k127_404069_21 4Fe-4S binding domain K18979 - 1.17.99.6 0.0000000000000000000682 94.0
WLSH1_k127_404069_22 PFAM regulatory protein, ArsR K21903 - - 0.00000000000000000007686 94.0
WLSH1_k127_404069_23 Response regulator receiver domain - - - 0.0000000000000000001225 94.0
WLSH1_k127_404069_24 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.0000000000000000002669 90.0
WLSH1_k127_404069_25 protein involved in the oxidation of intracellular sulfur K07236 - - 0.0000000000000007402 81.0
WLSH1_k127_404069_26 Roadblock LC7 family protein K07131 - - 0.000000000001126 72.0
WLSH1_k127_404069_27 - K21029 - 2.7.7.80 0.000000003413 61.0
WLSH1_k127_404069_28 cytochrome c biogenesis protein transmembrane region K06196 - - 0.000003229 59.0
WLSH1_k127_404069_29 Protein of unknown function (DUF3494) - - - 0.00004753 55.0
WLSH1_k127_404069_3 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 393.0
WLSH1_k127_404069_30 - - - - 0.00005496 50.0
WLSH1_k127_404069_4 oligoendopeptidase F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 381.0
WLSH1_k127_404069_5 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 335.0
WLSH1_k127_404069_6 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 303.0
WLSH1_k127_404069_7 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001429 284.0
WLSH1_k127_404069_8 Patch-forming domain C2 of tRNA-guanine transglycosylase K07557 GO:0002927,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000225 290.0
WLSH1_k127_404069_9 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000008179 201.0
WLSH1_k127_4101811_0 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 1.604e-273 848.0
WLSH1_k127_4101811_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 376.0
WLSH1_k127_4101811_10 Transferrin receptor-like dimerisation domain K01301,K14592 GO:0001505,GO:0003674,GO:0003824,GO:0004177,GO:0004180,GO:0004181,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0008239,GO:0008652,GO:0009056,GO:0009058,GO:0009986,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016021,GO:0016053,GO:0016787,GO:0016805,GO:0016810,GO:0016811,GO:0017171,GO:0018193,GO:0018200,GO:0018410,GO:0019538,GO:0019752,GO:0031224,GO:0031226,GO:0033218,GO:0034641,GO:0035608,GO:0035609,GO:0036211,GO:0042133,GO:0042135,GO:0042277,GO:0042558,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0046483,GO:0048518,GO:0048522,GO:0050129,GO:0050789,GO:0050794,GO:0051186,GO:0065007,GO:0065008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1900750,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1904492,GO:1904493 3.4.17.21 0.000000000001154 81.0
WLSH1_k127_4101811_11 Transcriptional regulator K11924 - - 0.00000000002317 67.0
WLSH1_k127_4101811_12 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000001452 74.0
WLSH1_k127_4101811_13 ACT domain protein - - - 0.0000000002739 66.0
WLSH1_k127_4101811_14 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000005374 55.0
WLSH1_k127_4101811_15 transferase activity, transferring acyl groups K14658,K17840 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.59 0.00001788 55.0
WLSH1_k127_4101811_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 312.0
WLSH1_k127_4101811_3 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001514 267.0
WLSH1_k127_4101811_4 LemA family K03744 - - 0.00000000000000000000000000000000000001252 151.0
WLSH1_k127_4101811_5 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000007282 156.0
WLSH1_k127_4101811_6 Methanol dehydrogenase K06872 - - 0.000000000000000000000000006689 119.0
WLSH1_k127_4101811_7 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000113 104.0
WLSH1_k127_4101811_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000604 91.0
WLSH1_k127_4101811_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000002741 86.0
WLSH1_k127_4316097_0 Conserved repeat domain - - - 0.0000000000000000000005761 112.0
WLSH1_k127_4316097_1 - - - - 0.0000305 55.0
WLSH1_k127_4365438_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 552.0
WLSH1_k127_4365438_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 553.0
WLSH1_k127_4365438_10 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.000000000000000000000000000000000000000000000000003397 191.0
WLSH1_k127_4365438_11 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000004092 191.0
WLSH1_k127_4365438_12 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000000001325 171.0
WLSH1_k127_4365438_13 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000003692 158.0
WLSH1_k127_4365438_14 hydrolase (HAD superfamily) K07025 - - 0.000000000000000000000000000000000000009114 155.0
WLSH1_k127_4365438_15 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.00000000000000000000000000000000000003325 164.0
WLSH1_k127_4365438_16 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000008448 155.0
WLSH1_k127_4365438_17 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000001008 144.0
WLSH1_k127_4365438_18 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000002582 129.0
WLSH1_k127_4365438_19 FG-GAP repeat - - - 0.0000000000000000000000000001387 136.0
WLSH1_k127_4365438_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 329.0
WLSH1_k127_4365438_20 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000006551 117.0
WLSH1_k127_4365438_21 Pkd domain containing protein - - - 0.0000000000000000006427 104.0
WLSH1_k127_4365438_22 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.00000000002712 76.0
WLSH1_k127_4365438_23 OmpA family - - - 0.00000003497 68.0
WLSH1_k127_4365438_24 Antifreeze protein type I - - - 0.00009947 54.0
WLSH1_k127_4365438_3 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005033 269.0
WLSH1_k127_4365438_4 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000001524 267.0
WLSH1_k127_4365438_5 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000006814 244.0
WLSH1_k127_4365438_6 TIGRFAM TIGR00268 family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000004866 241.0
WLSH1_k127_4365438_7 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000001374 221.0
WLSH1_k127_4365438_8 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000001571 203.0
WLSH1_k127_4365438_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000002505 198.0
WLSH1_k127_4393142_0 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000001016 218.0
WLSH1_k127_4393142_1 Sugar (and other) transporter - - - 0.0000000002103 72.0
WLSH1_k127_4764684_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.269e-198 629.0
WLSH1_k127_4764684_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 576.0
WLSH1_k127_4764684_10 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001284 265.0
WLSH1_k127_4764684_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005723 278.0
WLSH1_k127_4764684_12 - - - - 0.0000000000000000000000000000000000000000000000000006062 199.0
WLSH1_k127_4764684_13 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000065 190.0
WLSH1_k127_4764684_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000002412 184.0
WLSH1_k127_4764684_15 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000135 167.0
WLSH1_k127_4764684_16 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000004659 173.0
WLSH1_k127_4764684_17 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000006101 155.0
WLSH1_k127_4764684_18 Protein of unknown function (DUF357) K09728 - - 0.00000000000000000000000000000000007299 136.0
WLSH1_k127_4764684_19 Aminotransferase class-III K00823 - 2.6.1.19 0.000000000000000000000000000001103 125.0
WLSH1_k127_4764684_2 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 544.0
WLSH1_k127_4764684_20 TOPRIM - - - 0.0000000000000000006076 93.0
WLSH1_k127_4764684_21 PFAM Forkhead-associated protein - - - 0.000000000000000003502 99.0
WLSH1_k127_4764684_22 Belongs to the UPF0235 family K09131 - - 0.000000000001007 73.0
WLSH1_k127_4764684_23 protein conserved in archaea K09723 - - 0.000000000001371 76.0
WLSH1_k127_4764684_24 sequence-specific DNA binding - - - 0.000000005398 60.0
WLSH1_k127_4764684_25 transferase activity, transferring glycosyl groups K01186,K01371,K20276 - 3.2.1.18,3.4.22.38 0.0000002493 64.0
WLSH1_k127_4764684_26 membrane-associated protein domain - - - 0.0000008285 58.0
WLSH1_k127_4764684_27 haloacid dehalogenase-like hydrolase K07025 - - 0.00001942 54.0
WLSH1_k127_4764684_28 chlorophyll binding - - - 0.00003361 54.0
WLSH1_k127_4764684_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 418.0
WLSH1_k127_4764684_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 400.0
WLSH1_k127_4764684_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 333.0
WLSH1_k127_4764684_6 alcohol dehydrogenase K00008,K00060 - 1.1.1.103,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 322.0
WLSH1_k127_4764684_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003428 272.0
WLSH1_k127_4764684_8 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008702 286.0
WLSH1_k127_4764684_9 Conserved hypothetical ATP binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006426 261.0
WLSH1_k127_4844694_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 611.0
WLSH1_k127_4844694_1 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 423.0
WLSH1_k127_4844694_10 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.0000000000000000000000000000000000001002 144.0
WLSH1_k127_4844694_11 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000002422 133.0
WLSH1_k127_4844694_12 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.000000000000000000000000000007761 123.0
WLSH1_k127_4844694_13 NifU-like N terminal domain K04488 - - 0.000000000000000000000000009401 121.0
WLSH1_k127_4844694_14 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.00000000000000000000001595 109.0
WLSH1_k127_4844694_15 Belongs to the UPF0251 family - - - 0.00000000000000000000009645 101.0
WLSH1_k127_4844694_16 DsrE/DsrF-like family - - - 0.00000000000000000178 90.0
WLSH1_k127_4844694_17 Bacterio-opsin activator HTH K06930 - - 0.00000000002526 72.0
WLSH1_k127_4844694_18 Protein of unknown function DUF134 - - - 0.0000000001 64.0
WLSH1_k127_4844694_19 4Fe-4S binding domain K03616 - - 0.00001864 51.0
WLSH1_k127_4844694_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 398.0
WLSH1_k127_4844694_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 310.0
WLSH1_k127_4844694_4 CobQ/CobB/MinD/ParA nucleotide binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009448 283.0
WLSH1_k127_4844694_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005564 262.0
WLSH1_k127_4844694_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000006057 257.0
WLSH1_k127_4844694_7 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000002596 215.0
WLSH1_k127_4844694_8 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000009708 176.0
WLSH1_k127_4844694_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000001042 153.0
WLSH1_k127_4976528_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 551.0
WLSH1_k127_4976528_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000001167 177.0
WLSH1_k127_4976528_2 Sulfite exporter TauE/SafE K07090 - - 0.000000001085 68.0
WLSH1_k127_5011553_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 393.0
WLSH1_k127_5011553_1 Protein of unknown function (DUF1616) - - - 0.000000000000000000000000000000000000000000000000000000006095 211.0
WLSH1_k127_5011553_2 membrane - - - 0.000000000000000218 88.0
WLSH1_k127_5011553_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000729 44.0
WLSH1_k127_5299160_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 487.0
WLSH1_k127_5299160_1 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 333.0
WLSH1_k127_5299160_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000003718 239.0
WLSH1_k127_5299160_3 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000000002613 203.0
WLSH1_k127_5299160_4 COG0119 Isopropylmalate homocitrate citramalate synthases K01649 - 2.3.3.13 0.00002578 47.0
WLSH1_k127_5458805_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 473.0
WLSH1_k127_5458805_1 Arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 377.0
WLSH1_k127_5458805_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000001317 138.0
WLSH1_k127_5523521_0 Galactose oxidase, central domain - - - 0.000000000000000000000000000000000000000000001116 183.0
WLSH1_k127_5523521_1 Protein of unknown function (DUF835) - - - 0.0000405 53.0
WLSH1_k127_5738731_0 Cell division protein 48, CDC48, domain 2 K13525 - - 2.472e-275 865.0
WLSH1_k127_5738731_1 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 599.0
WLSH1_k127_5738731_10 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000006976 194.0
WLSH1_k127_5738731_11 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000001778 186.0
WLSH1_k127_5738731_12 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000006802 177.0
WLSH1_k127_5738731_13 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000001415 179.0
WLSH1_k127_5738731_14 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000002053 170.0
WLSH1_k127_5738731_15 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000004043 166.0
WLSH1_k127_5738731_16 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000001026 156.0
WLSH1_k127_5738731_17 Thioredoxin K03671 - - 0.000000000000000000000000000000000002908 141.0
WLSH1_k127_5738731_18 - - - - 0.000000000000000000000000000000002233 149.0
WLSH1_k127_5738731_19 PRC-barrel domain - - - 0.0000000000000000000000002149 107.0
WLSH1_k127_5738731_2 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00186 - 1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 349.0
WLSH1_k127_5738731_20 protein conserved in archaea - - - 0.0000000000000000000000007377 106.0
WLSH1_k127_5738731_21 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000009075 107.0
WLSH1_k127_5738731_22 PRC-barrel domain - - - 0.000000000000000004483 87.0
WLSH1_k127_5738731_23 TPR repeat-containing protein - - - 0.000000000002853 80.0
WLSH1_k127_5738731_24 glutamine amidotransferase K07008 - 3.5.1.118 0.0000000001319 71.0
WLSH1_k127_5738731_25 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000002838 66.0
WLSH1_k127_5738731_26 OsmC-like protein - - - 0.000000001237 65.0
WLSH1_k127_5738731_27 - - - - 0.00002946 51.0
WLSH1_k127_5738731_3 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 313.0
WLSH1_k127_5738731_4 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009786 261.0
WLSH1_k127_5738731_5 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008534 239.0
WLSH1_k127_5738731_6 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.0000000000000000000000000000000000000000000000000000000000006757 215.0
WLSH1_k127_5738731_7 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000946 236.0
WLSH1_k127_5738731_8 PFAM Thiamine pyrophosphate enzyme, C-terminal K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000002182 210.0
WLSH1_k127_5738731_9 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000004192 209.0
WLSH1_k127_5778094_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 1.532e-217 703.0
WLSH1_k127_5778094_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 573.0
WLSH1_k127_5778094_10 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000493 168.0
WLSH1_k127_5778094_11 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000000000000008191 131.0
WLSH1_k127_5778094_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 387.0
WLSH1_k127_5778094_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 379.0
WLSH1_k127_5778094_4 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001349 286.0
WLSH1_k127_5778094_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000003796 269.0
WLSH1_k127_5778094_6 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000276 247.0
WLSH1_k127_5778094_7 4Fe-4S dicluster domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000001218 218.0
WLSH1_k127_5778094_9 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000004899 163.0
WLSH1_k127_5966537_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1292.0
WLSH1_k127_5966537_1 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 1.699e-243 827.0
WLSH1_k127_5966537_10 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000000000000000002853 170.0
WLSH1_k127_5966537_11 archaeal Zn-finger protein - - - 0.0000000000000000000000000000000000000007998 155.0
WLSH1_k127_5966537_12 Methyltransferase domain K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000003117 147.0
WLSH1_k127_5966537_13 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000003698 128.0
WLSH1_k127_5966537_14 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000001838 140.0
WLSH1_k127_5966537_15 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000416 119.0
WLSH1_k127_5966537_16 PFAM Rhomboid family protein K07059 - - 0.00000000000000000001482 102.0
WLSH1_k127_5966537_17 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000005118 92.0
WLSH1_k127_5966537_18 Carbohydrate binding module (family 35) - - - 0.0006758 51.0
WLSH1_k127_5966537_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 8.298e-221 688.0
WLSH1_k127_5966537_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 597.0
WLSH1_k127_5966537_4 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007727 462.0
WLSH1_k127_5966537_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 437.0
WLSH1_k127_5966537_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 413.0
WLSH1_k127_5966537_7 4Fe-4S single cluster domain K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 366.0
WLSH1_k127_5966537_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000005928 261.0
WLSH1_k127_5966537_9 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000000000000000000000006435 201.0
WLSH1_k127_6089159_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 461.0
WLSH1_k127_6089159_1 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 364.0
WLSH1_k127_6089159_10 COG3209 Rhs family protein - - - 0.00000000000002166 87.0
WLSH1_k127_6089159_11 methyltransferase K07755 - 2.1.1.137 0.00000000000003914 81.0
WLSH1_k127_6089159_12 Psort location Periplasmic, score K01999 - - 0.00000000002473 76.0
WLSH1_k127_6089159_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000001582 67.0
WLSH1_k127_6089159_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.000007469 58.0
WLSH1_k127_6089159_15 Lamin Tail Domain - - - 0.00001467 59.0
WLSH1_k127_6089159_16 Protein of unknown function (DUF1616) - - - 0.00003577 55.0
WLSH1_k127_6089159_17 4-vinyl reductase, 4VR K06382,K07013 - 3.1.3.16 0.0001041 53.0
WLSH1_k127_6089159_18 - - - - 0.0001064 52.0
WLSH1_k127_6089159_19 efflux transmembrane transporter activity K02004 - - 0.0001344 55.0
WLSH1_k127_6089159_2 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 302.0
WLSH1_k127_6089159_20 MacB-like periplasmic core domain K09808 GO:0005575,GO:0005623,GO:0005886,GO:0008104,GO:0008150,GO:0016020,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.000316 52.0
WLSH1_k127_6089159_21 Transcriptional regulator K07722 - - 0.0004679 46.0
WLSH1_k127_6089159_3 PFAM Iron-containing alcohol dehydrogenase K00005,K08317 - 1.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000203 257.0
WLSH1_k127_6089159_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000002165 211.0
WLSH1_k127_6089159_5 Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000000000000000000000000004668 191.0
WLSH1_k127_6089159_6 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000004118 199.0
WLSH1_k127_6089159_7 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000007452 185.0
WLSH1_k127_6089159_8 Acts probably as a methyl group carrier between MttB and either MtbA or MtaA K14084 - - 0.0000000000000000000000000000000000000000004365 166.0
WLSH1_k127_6089159_9 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.00000000000000000000000000000001746 147.0
WLSH1_k127_6321507_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 3.362e-228 727.0
WLSH1_k127_6321507_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 556.0
WLSH1_k127_6321507_10 structural constituent of ribosome K02984 - - 0.0000000000000000000000000000000000000000000000000000000000000001284 231.0
WLSH1_k127_6321507_11 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000589 195.0
WLSH1_k127_6321507_12 PFAM Peptidase - - - 0.00000000000000000000000000000000000005596 151.0
WLSH1_k127_6321507_13 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000001276 130.0
WLSH1_k127_6321507_14 Ribonuclease H K03469 - 3.1.26.4 0.00000000000000000000000000008032 120.0
WLSH1_k127_6321507_15 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000001268 131.0
WLSH1_k127_6321507_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000001059 103.0
WLSH1_k127_6321507_17 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000001232 102.0
WLSH1_k127_6321507_18 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000002579 95.0
WLSH1_k127_6321507_19 - - - - 0.0000000000000001535 90.0
WLSH1_k127_6321507_2 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 529.0
WLSH1_k127_6321507_20 Domain of unknown function (DUF749) - - - 0.0000001766 56.0
WLSH1_k127_6321507_21 - - - - 0.000004447 55.0
WLSH1_k127_6321507_3 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 359.0
WLSH1_k127_6321507_4 PFAM Peptidase family M20 M25 M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 327.0
WLSH1_k127_6321507_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007101 296.0
WLSH1_k127_6321507_6 SMART ATPase, AAA type, core K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003215 263.0
WLSH1_k127_6321507_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004194 261.0
WLSH1_k127_6321507_8 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002548 256.0
WLSH1_k127_6321507_9 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000004125 242.0
WLSH1_k127_6412740_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000465 194.0
WLSH1_k127_6412740_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000001069 172.0
WLSH1_k127_6412740_2 - - - - 0.00000000000000000000000000000000000001998 157.0
WLSH1_k127_6412740_3 - - - - 0.00000000000000000000000000000002076 130.0
WLSH1_k127_6412740_4 - - - - 0.00000000000000000068 95.0
WLSH1_k127_6412740_6 PHP domain protein - - - 0.000001952 52.0
WLSH1_k127_6412740_7 Tetratricopeptide repeat - - - 0.00003488 53.0
WLSH1_k127_6607661_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 608.0
WLSH1_k127_6607661_1 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 321.0
WLSH1_k127_6607661_2 Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000124 264.0
WLSH1_k127_6607661_3 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000000000000000002519 257.0
WLSH1_k127_6607661_4 Protein of unknown function TPD sequence-motif - - - 0.00000000000000000000000000000000000000000000000000000000000002605 231.0
WLSH1_k127_6700474_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 640.0
WLSH1_k127_6700474_1 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 485.0
WLSH1_k127_6700474_10 - - - - 0.00001317 57.0
WLSH1_k127_6700474_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 437.0
WLSH1_k127_6700474_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 384.0
WLSH1_k127_6700474_4 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 368.0
WLSH1_k127_6700474_5 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005169 257.0
WLSH1_k127_6700474_6 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000003153 245.0
WLSH1_k127_6700474_7 - - - - 0.00000000006088 72.0
WLSH1_k127_6700474_8 Transcriptional regulator K07108 - - 0.000000001023 64.0
WLSH1_k127_6700474_9 - - - - 0.00001142 55.0
WLSH1_k127_6768003_0 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000003653 150.0
WLSH1_k127_6768003_1 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000009201 151.0
WLSH1_k127_6802209_0 NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K17994,K18007 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 349.0
WLSH1_k127_6802209_1 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001439 275.0
WLSH1_k127_6802209_2 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000004604 259.0
WLSH1_k127_6802209_3 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000002349 226.0
WLSH1_k127_6802209_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000001311 66.0
WLSH1_k127_6856844_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001504 295.0
WLSH1_k127_6856844_1 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000001116 213.0
WLSH1_k127_6856844_2 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000000128 120.0
WLSH1_k127_6856844_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000001 95.0
WLSH1_k127_6908568_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 583.0
WLSH1_k127_6908568_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 513.0
WLSH1_k127_6908568_10 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000001453 218.0
WLSH1_k127_6908568_11 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000000000002517 215.0
WLSH1_k127_6908568_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000268 209.0
WLSH1_k127_6908568_13 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001299 190.0
WLSH1_k127_6908568_14 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000001218 175.0
WLSH1_k127_6908568_15 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000001381 184.0
WLSH1_k127_6908568_16 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000000000000001425 164.0
WLSH1_k127_6908568_17 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000002067 100.0
WLSH1_k127_6908568_18 Ribbon-helix-helix protein, copG family K07722 - - 0.000000000000000000001319 98.0
WLSH1_k127_6908568_19 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000005451 100.0
WLSH1_k127_6908568_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 476.0
WLSH1_k127_6908568_20 PFAM Forkhead-associated protein - - - 0.0000000000000000007344 99.0
WLSH1_k127_6908568_21 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000000008188 86.0
WLSH1_k127_6908568_22 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000000002306 82.0
WLSH1_k127_6908568_23 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000000001293 77.0
WLSH1_k127_6908568_24 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000003921 75.0
WLSH1_k127_6908568_25 Flavodoxin domain - - - 0.000000001874 68.0
WLSH1_k127_6908568_26 Major facilitator superfamily K08222 - - 0.0000000633 64.0
WLSH1_k127_6908568_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 471.0
WLSH1_k127_6908568_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 314.0
WLSH1_k127_6908568_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 321.0
WLSH1_k127_6908568_6 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004288 282.0
WLSH1_k127_6908568_7 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004584 270.0
WLSH1_k127_6908568_8 TatD related DNase K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005038 269.0
WLSH1_k127_6908568_9 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008727 263.0
WLSH1_k127_7118969_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 2.01e-321 1000.0
WLSH1_k127_7118969_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 8.483e-252 793.0
WLSH1_k127_7118969_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 347.0
WLSH1_k127_7118969_11 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 332.0
WLSH1_k127_7118969_12 TIGRFAM phosphate ABC transporter K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 300.0
WLSH1_k127_7118969_13 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 296.0
WLSH1_k127_7118969_14 Helix-turn-helix XRE-family like proteins K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000999 289.0
WLSH1_k127_7118969_15 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008701 287.0
WLSH1_k127_7118969_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002935 279.0
WLSH1_k127_7118969_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002934 255.0
WLSH1_k127_7118969_18 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002363 265.0
WLSH1_k127_7118969_19 Pfam:DUF137 K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000000000000000000000000002156 250.0
WLSH1_k127_7118969_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 3.028e-241 751.0
WLSH1_k127_7118969_20 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000000000000000000000000000000002194 246.0
WLSH1_k127_7118969_21 Belongs to the ompA family K20276 - - 0.000000000000000000000000000000000000000000000000000000000005219 240.0
WLSH1_k127_7118969_22 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000003528 194.0
WLSH1_k127_7118969_23 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000008911 188.0
WLSH1_k127_7118969_24 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000002618 201.0
WLSH1_k127_7118969_25 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000002053 175.0
WLSH1_k127_7118969_26 Signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000007776 169.0
WLSH1_k127_7118969_27 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000003132 156.0
WLSH1_k127_7118969_28 GvpD gas vesicle protein - - - 0.0000000000000000000000000000000000000005794 156.0
WLSH1_k127_7118969_29 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000006891 147.0
WLSH1_k127_7118969_3 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 584.0
WLSH1_k127_7118969_30 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.000000000000000000000000000544 119.0
WLSH1_k127_7118969_31 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000005144 104.0
WLSH1_k127_7118969_32 - - - - 0.00000000000000000000008501 113.0
WLSH1_k127_7118969_33 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000002592 104.0
WLSH1_k127_7118969_34 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000003362 103.0
WLSH1_k127_7118969_35 CAAX protease self-immunity - - - 0.0000000000000000000007776 110.0
WLSH1_k127_7118969_36 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000000000000000000001243 100.0
WLSH1_k127_7118969_37 cheY-homologous receiver domain - - - 0.000000000000000000177 96.0
WLSH1_k127_7118969_38 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.0000000001013 64.0
WLSH1_k127_7118969_39 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000001309 65.0
WLSH1_k127_7118969_4 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 483.0
WLSH1_k127_7118969_40 Belongs to the UPF0200 family - - - 0.0000000002016 73.0
WLSH1_k127_7118969_41 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000002503 65.0
WLSH1_k127_7118969_42 Tetratricopeptide repeats - - - 0.0000003545 62.0
WLSH1_k127_7118969_43 membrane-associated protein domain - - - 0.000005564 56.0
WLSH1_k127_7118969_44 Protein of unknown function (DUF3198) - - - 0.00002074 52.0
WLSH1_k127_7118969_45 H ACA RNA-protein complex K07569 - - 0.000308 49.0
WLSH1_k127_7118969_5 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 475.0
WLSH1_k127_7118969_6 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 445.0
WLSH1_k127_7118969_7 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 403.0
WLSH1_k127_7118969_8 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 413.0
WLSH1_k127_7118969_9 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 376.0
WLSH1_k127_7134931_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.288e-205 652.0
WLSH1_k127_7164744_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1110.0
WLSH1_k127_7164744_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 600.0
WLSH1_k127_7164744_10 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001257 284.0
WLSH1_k127_7164744_11 HisG, C-terminal domain K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000008092 268.0
WLSH1_k127_7164744_12 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 256.0
WLSH1_k127_7164744_13 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000007938 227.0
WLSH1_k127_7164744_14 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001223 231.0
WLSH1_k127_7164744_15 ferredoxin oxidoreductase K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000007564 225.0
WLSH1_k127_7164744_16 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000006778 222.0
WLSH1_k127_7164744_17 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000004129 207.0
WLSH1_k127_7164744_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000003966 199.0
WLSH1_k127_7164744_19 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000901 203.0
WLSH1_k127_7164744_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 522.0
WLSH1_k127_7164744_20 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000001557 206.0
WLSH1_k127_7164744_21 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000004958 197.0
WLSH1_k127_7164744_22 - - - - 0.000000000000000000000000000000000000002884 155.0
WLSH1_k127_7164744_23 hmm pf03415 K08587 - 3.4.22.8 0.000000000000000000000000102 121.0
WLSH1_k127_7164744_24 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000001109 113.0
WLSH1_k127_7164744_25 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000006452 112.0
WLSH1_k127_7164744_26 PFAM Forkhead-associated protein - - - 0.0000000000000000000004058 109.0
WLSH1_k127_7164744_27 cheY-homologous receiver domain K03413 - - 0.0000000000000000001435 93.0
WLSH1_k127_7164744_28 - - - - 0.00000000000000005215 89.0
WLSH1_k127_7164744_29 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000006401 85.0
WLSH1_k127_7164744_3 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 490.0
WLSH1_k127_7164744_30 Acetyltransferase, gnat family - - - 0.0000000000004585 79.0
WLSH1_k127_7164744_31 but it may be involved in stabilization of the trimeric complex - - - 0.0000000003326 62.0
WLSH1_k127_7164744_32 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000003366 65.0
WLSH1_k127_7164744_4 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
WLSH1_k127_7164744_5 NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K17994,K18007 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 359.0
WLSH1_k127_7164744_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 327.0
WLSH1_k127_7164744_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 334.0
WLSH1_k127_7164744_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 331.0
WLSH1_k127_7164744_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 351.0
WLSH1_k127_7317964_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000006666 269.0
WLSH1_k127_7317964_1 extracellular matrix structural constituent K02035 - - 0.0000000000000005264 84.0
WLSH1_k127_7317964_2 Pro-kumamolisin, activation domain - - - 0.00002085 55.0
WLSH1_k127_7338555_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 520.0
WLSH1_k127_7338555_1 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 520.0
WLSH1_k127_7338555_10 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 0.0000000000006222 84.0
WLSH1_k127_7338555_11 - - - - 0.0002773 49.0
WLSH1_k127_7338555_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004791 264.0
WLSH1_k127_7338555_3 peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000008822 228.0
WLSH1_k127_7338555_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000001676 201.0
WLSH1_k127_7338555_5 nitroreductase - - - 0.00000000000000000000000000000000000000000000000263 181.0
WLSH1_k127_7338555_6 EamA-like transporter family - - - 0.000000000000000000004899 104.0
WLSH1_k127_7338555_7 Pkd domain containing protein - - - 0.00000000000000007458 95.0
WLSH1_k127_7338555_8 TIGRFAM C_GCAxxG_C_C family protein - - - 0.0000000000000001041 86.0
WLSH1_k127_7338555_9 Ion channel - - - 0.00000000000002569 77.0
WLSH1_k127_7349220_0 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 300.0
WLSH1_k127_7349220_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 302.0
WLSH1_k127_7349220_2 Oxidoreductase domain protein K18855 - 1.1.1.374 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
WLSH1_k127_7349220_3 PFAM Trm112p-like protein - - - 0.0003443 44.0
WLSH1_k127_7512744_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 521.0
WLSH1_k127_7512744_1 Trm112p-like protein - - - 0.000000000000000004361 85.0
WLSH1_k127_7512744_2 glucose sorbosone - - - 0.0000000000001427 83.0
WLSH1_k127_7512744_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00001101 53.0
WLSH1_k127_7717112_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 517.0
WLSH1_k127_7717112_1 pfkB family carbohydrate kinase K22026 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006213,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008617,GO:0008906,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009129,GO:0009130,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042278,GO:0042455,GO:0043167,GO:0043168,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046033,GO:0046035,GO:0046085,GO:0046087,GO:0046102,GO:0046128,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1905108 2.7.1.213,2.7.1.73 0.000000000000007521 79.0
WLSH1_k127_7881396_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 7.957e-248 782.0
WLSH1_k127_7881396_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 579.0
WLSH1_k127_7881396_10 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 354.0
WLSH1_k127_7881396_11 methanogenesis marker protein 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 331.0
WLSH1_k127_7881396_12 COG0477 Permeases of the major facilitator superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 302.0
WLSH1_k127_7881396_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002022 284.0
WLSH1_k127_7881396_14 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001194 252.0
WLSH1_k127_7881396_15 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002329 244.0
WLSH1_k127_7881396_16 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.00000000000000000000000000000000000000000000000000000000000000001381 231.0
WLSH1_k127_7881396_17 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000005412 231.0
WLSH1_k127_7881396_18 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000007387 214.0
WLSH1_k127_7881396_19 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000001106 185.0
WLSH1_k127_7881396_2 Proton-conducting membrane transporter K05565,K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 584.0
WLSH1_k127_7881396_20 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000000000000001683 164.0
WLSH1_k127_7881396_21 lactate oxidation K16950 - - 0.000000000000000000000000000000000000000000486 173.0
WLSH1_k127_7881396_22 4Fe-4S dicluster domain K00338,K14121,K22164,K22176 - 1.1.98.4,1.5.98.3,1.6.5.3 0.0000000000000000000000000000000101 138.0
WLSH1_k127_7881396_23 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000001524 124.0
WLSH1_k127_7881396_24 NADH ubiquinone oxidoreductase 27 kD subunit K00332,K22160 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000002056 120.0
WLSH1_k127_7881396_25 NADH ubiquinone oxidoreductase subunit 11 or 4L (Chain K) K00340,K22166 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000009868 117.0
WLSH1_k127_7881396_26 NADH ubiquinone oxidoreductase subunit 3 (Chain a) K00330,K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3,1.6.5.3 0.00000000000000000000000002335 112.0
WLSH1_k127_7881396_27 PFAM molybdopterin-guanine dinucleotide biosynthesis MobB region K03753 - - 0.0000000000000000000000002435 118.0
WLSH1_k127_7881396_28 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000009202 73.0
WLSH1_k127_7881396_29 Protein of unknown function (DUF2797) - - - 0.00000007537 63.0
WLSH1_k127_7881396_3 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 519.0
WLSH1_k127_7881396_30 cellulase activity - - - 0.00002997 57.0
WLSH1_k127_7881396_4 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 487.0
WLSH1_k127_7881396_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 451.0
WLSH1_k127_7881396_6 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 400.0
WLSH1_k127_7881396_7 Proton-conducting membrane transporter K22168 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 392.0
WLSH1_k127_7881396_8 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K00343,K22169 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 384.0
WLSH1_k127_7881396_9 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 373.0
WLSH1_k127_7958384_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1050.0
WLSH1_k127_7958384_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 483.0
WLSH1_k127_7958384_10 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000001578 163.0
WLSH1_k127_7958384_11 exosome subunit K07581 - - 0.00000000000000000000003184 104.0
WLSH1_k127_7958384_12 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00188 - 1.2.7.7 0.0000000000000000000001085 108.0
WLSH1_k127_7958384_13 Belongs to the PDCD5 family K06875 - - 0.0000000000000000000007736 98.0
WLSH1_k127_7958384_14 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000004171 93.0
WLSH1_k127_7958384_15 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000003729 76.0
WLSH1_k127_7958384_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02488 - 2.7.7.65 0.0003221 53.0
WLSH1_k127_7958384_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 397.0
WLSH1_k127_7958384_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 328.0
WLSH1_k127_7958384_4 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005288 297.0
WLSH1_k127_7958384_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000003001 200.0
WLSH1_k127_7958384_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.000000000000000000000000000000000000000000000000000001408 201.0
WLSH1_k127_7958384_7 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000005184 198.0
WLSH1_k127_7958384_8 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.000000000000000000000000000000000000000000000000006447 188.0
WLSH1_k127_7958384_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000001032 170.0
WLSH1_k127_7995786_0 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000001075 203.0
WLSH1_k127_7995786_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000007088 184.0
WLSH1_k127_7995786_2 Peptidase m28 - - - 0.00000000006475 76.0
WLSH1_k127_8008901_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 462.0
WLSH1_k127_8008901_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 449.0
WLSH1_k127_8008901_10 methyltransferase - - - 0.0000000000000002242 89.0
WLSH1_k127_8008901_12 - - - - 0.00001443 54.0
WLSH1_k127_8008901_2 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 366.0
WLSH1_k127_8008901_3 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 332.0
WLSH1_k127_8008901_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002513 281.0
WLSH1_k127_8008901_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000007605 222.0
WLSH1_k127_8008901_7 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000002173 167.0
WLSH1_k127_8008901_8 Histidine kinase-like ATPases - - - 0.00000000000000000000000002557 126.0
WLSH1_k127_8008901_9 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000000005376 101.0
WLSH1_k127_8121360_0 NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K17994,K18007 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 352.0
WLSH1_k127_8121360_1 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000009064 121.0
WLSH1_k127_8121360_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000005228 63.0
WLSH1_k127_8302924_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 386.0
WLSH1_k127_8302924_1 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001551 272.0
WLSH1_k127_8302924_2 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000151 111.0
WLSH1_k127_8302924_3 - - - - 0.00000000000002991 76.0
WLSH1_k127_8302924_4 - - - - 0.0001407 48.0
WLSH1_k127_8339628_0 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 411.0
WLSH1_k127_8339628_1 COG0531 Amino acid transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 402.0
WLSH1_k127_8339628_10 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000007023 244.0
WLSH1_k127_8339628_11 PhoU domain - - - 0.0000000000000000000000000000000000000000000000000000000000003953 226.0
WLSH1_k127_8339628_12 PFAM DoxX family protein K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000000007559 194.0
WLSH1_k127_8339628_13 B12 binding domain K14084 - - 0.00000000000000000000000000000000000000000000000002377 187.0
WLSH1_k127_8339628_14 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000001724 162.0
WLSH1_k127_8339628_15 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000008256 161.0
WLSH1_k127_8339628_16 Glycine cleavage H-protein K02437 - - 0.0000000000000000000000000000000000000004575 153.0
WLSH1_k127_8339628_17 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000002434 149.0
WLSH1_k127_8339628_18 flavin reductase - - - 0.000000000000000000000000000000000002935 144.0
WLSH1_k127_8339628_19 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000009865 144.0
WLSH1_k127_8339628_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 310.0
WLSH1_k127_8339628_20 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000000558 131.0
WLSH1_k127_8339628_21 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000017 127.0
WLSH1_k127_8339628_22 nucleotide metabolic process - - - 0.000000000000000000000000002414 120.0
WLSH1_k127_8339628_23 chloroplast fission K03531 - - 0.00000000000000000002278 102.0
WLSH1_k127_8339628_24 Peptidase family M28 - - - 0.00000000000000000003821 102.0
WLSH1_k127_8339628_25 Hint domain - - - 0.000000000000000002429 102.0
WLSH1_k127_8339628_26 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.00000000000008966 73.0
WLSH1_k127_8339628_27 OmpA family - - - 0.0000000001073 76.0
WLSH1_k127_8339628_3 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 285.0
WLSH1_k127_8339628_4 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002292 310.0
WLSH1_k127_8339628_5 Kef-type K transport K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004157 289.0
WLSH1_k127_8339628_6 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006529 274.0
WLSH1_k127_8339628_7 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007339 276.0
WLSH1_k127_8339628_8 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002252 251.0
WLSH1_k127_8339628_9 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.00000000000000000000000000000000000000000000000000000000000000000002739 254.0
WLSH1_k127_8385266_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000001214 254.0
WLSH1_k127_8385266_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000003209 146.0
WLSH1_k127_8385266_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000002962 124.0
WLSH1_k127_8424491_0 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 482.0
WLSH1_k127_8424491_1 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 365.0
WLSH1_k127_8424491_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 334.0
WLSH1_k127_8424491_3 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000002628 214.0
WLSH1_k127_8469189_0 Citrate transporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 487.0
WLSH1_k127_8469189_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 338.0
WLSH1_k127_8469189_2 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.000000000000000000000000000000000000001233 168.0
WLSH1_k127_8469189_3 Belongs to the peptidase S8 family - - - 0.00003554 57.0
WLSH1_k127_8482436_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 7.561e-217 684.0
WLSH1_k127_8482436_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 328.0
WLSH1_k127_8482436_10 structural constituent of ribosome K02907 - - 0.000000000000000000000000000000000000000001082 161.0
WLSH1_k127_8482436_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001092 169.0
WLSH1_k127_8482436_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000008748 150.0
WLSH1_k127_8482436_13 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000002052 151.0
WLSH1_k127_8482436_14 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000701 146.0
WLSH1_k127_8482436_15 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000004365 150.0
WLSH1_k127_8482436_16 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000008193 139.0
WLSH1_k127_8482436_17 ribosomal protein L24 K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000145 101.0
WLSH1_k127_8482436_18 ribosomal protein S14 K02954 - - 0.000000000000000002486 93.0
WLSH1_k127_8482436_19 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000000000009519 82.0
WLSH1_k127_8482436_2 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000095 231.0
WLSH1_k127_8482436_3 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000002463 222.0
WLSH1_k127_8482436_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000009089 211.0
WLSH1_k127_8482436_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000003232 201.0
WLSH1_k127_8482436_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000006697 199.0
WLSH1_k127_8482436_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001024 191.0
WLSH1_k127_8482436_8 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000008603 181.0
WLSH1_k127_8482436_9 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000002958 177.0
WLSH1_k127_8553784_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 501.0
WLSH1_k127_8553784_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 338.0
WLSH1_k127_8553784_2 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 309.0
WLSH1_k127_8553784_3 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000001338 256.0
WLSH1_k127_8553784_4 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000006501 239.0
WLSH1_k127_8553784_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000001347 216.0
WLSH1_k127_8553784_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000003068 192.0
WLSH1_k127_8553784_7 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000001151 158.0
WLSH1_k127_8553784_8 PFAM SMP-30 Gluconolaconase - - - 0.00000000000007123 86.0
WLSH1_k127_8553784_9 - - - - 0.000000000002021 78.0
WLSH1_k127_8564474_0 acetyl-CoA hydrolase transferase - - - 5.276e-218 695.0
WLSH1_k127_8564474_1 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 411.0
WLSH1_k127_8564474_10 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.00000000000000000000000000000000000852 144.0
WLSH1_k127_8564474_11 homolog of PrgY (pheromone shutdown protein) - - - 0.00000000000000000000000000001121 128.0
WLSH1_k127_8564474_12 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000008118 97.0
WLSH1_k127_8564474_13 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000009227 93.0
WLSH1_k127_8564474_14 translation initiation factor activity K03680 - - 0.0000000001273 73.0
WLSH1_k127_8564474_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 363.0
WLSH1_k127_8564474_3 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 357.0
WLSH1_k127_8564474_4 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 308.0
WLSH1_k127_8564474_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 290.0
WLSH1_k127_8564474_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001487 274.0
WLSH1_k127_8564474_7 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000001626 240.0
WLSH1_k127_8564474_8 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000001587 221.0
WLSH1_k127_8564474_9 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000006719 175.0
WLSH1_k127_8581766_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.083e-198 633.0
WLSH1_k127_8581766_1 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 419.0
WLSH1_k127_8581766_10 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000000001568 148.0
WLSH1_k127_8581766_11 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000003395 167.0
WLSH1_k127_8581766_12 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000003093 146.0
WLSH1_k127_8581766_13 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000000000000000000000000000000276 133.0
WLSH1_k127_8581766_14 histidine kinase A domain protein - - - 0.0000000000000000000000000000003062 144.0
WLSH1_k127_8581766_15 Uncharacterized ArCR, COG1888 K09732 - - 0.0000000000000000000000000003713 116.0
WLSH1_k127_8581766_17 Kelch repeat-containing protein - - - 0.000000000000008732 88.0
WLSH1_k127_8581766_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000005283 87.0
WLSH1_k127_8581766_19 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000005984 72.0
WLSH1_k127_8581766_2 Nickel-dependent hydrogenase K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 340.0
WLSH1_k127_8581766_20 - - - - 0.000000000001055 69.0
WLSH1_k127_8581766_23 PFAM peptidase M52 hydrogen uptake protein K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.00000018 63.0
WLSH1_k127_8581766_3 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001051 286.0
WLSH1_k127_8581766_4 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006154 278.0
WLSH1_k127_8581766_5 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000678 289.0
WLSH1_k127_8581766_6 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000000000003707 226.0
WLSH1_k127_8581766_7 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000000000000000000000006629 209.0
WLSH1_k127_8581766_8 hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000001098 207.0
WLSH1_k127_8581766_9 Phenazine biosynthesis protein phzf family - - - 0.0000000000000000000000000000000000000000000000009082 186.0
WLSH1_k127_8677905_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 359.0
WLSH1_k127_8677905_1 ATPases associated with a variety of cellular activities K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 321.0
WLSH1_k127_8677905_2 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003507 274.0
WLSH1_k127_8677905_3 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000001489 209.0
WLSH1_k127_8677905_4 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000001477 186.0
WLSH1_k127_8677905_5 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000001148 172.0
WLSH1_k127_8677905_6 Sodium Bile acid symporter family K03453 - - 0.00000000000000000000000000000002929 138.0
WLSH1_k127_8677905_7 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 0.00000000000000000805 83.0
WLSH1_k127_8677905_8 Bacterial PH domain - - - 0.000000001192 67.0
WLSH1_k127_8765000_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.644e-242 767.0
WLSH1_k127_8765000_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 1.305e-213 692.0
WLSH1_k127_8765000_10 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 290.0
WLSH1_k127_8765000_11 LUD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001001 304.0
WLSH1_k127_8765000_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007274 282.0
WLSH1_k127_8765000_13 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001062 260.0
WLSH1_k127_8765000_14 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002135 267.0
WLSH1_k127_8765000_15 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004017 267.0
WLSH1_k127_8765000_16 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000334 259.0
WLSH1_k127_8765000_17 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000008093 252.0
WLSH1_k127_8765000_18 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003959 259.0
WLSH1_k127_8765000_19 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000002092 248.0
WLSH1_k127_8765000_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.18e-208 669.0
WLSH1_k127_8765000_20 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002756 254.0
WLSH1_k127_8765000_21 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000133 248.0
WLSH1_k127_8765000_22 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000001696 241.0
WLSH1_k127_8765000_23 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000111 229.0
WLSH1_k127_8765000_24 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000008589 224.0
WLSH1_k127_8765000_25 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000006228 211.0
WLSH1_k127_8765000_26 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family - - - 0.000000000000000000000000000000000000000000000000000003321 198.0
WLSH1_k127_8765000_27 domain protein - - - 0.0000000000000000000000000000000000000000000000000002525 214.0
WLSH1_k127_8765000_28 Membrane - - - 0.0000000000000000000000000000000000000000000137 171.0
WLSH1_k127_8765000_29 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000000005425 175.0
WLSH1_k127_8765000_3 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 617.0
WLSH1_k127_8765000_30 transcription regulator activity - - - 0.00000000000000000000000000000000000000007945 155.0
WLSH1_k127_8765000_31 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000001404 159.0
WLSH1_k127_8765000_32 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000429 144.0
WLSH1_k127_8765000_33 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000004012 154.0
WLSH1_k127_8765000_34 Universal stress protein family - - - 0.000000000000000000000000000000001504 135.0
WLSH1_k127_8765000_35 serine threonine protein kinase - - - 0.00000000000000000004736 102.0
WLSH1_k127_8765000_36 - - - - 0.0000000000000000001524 100.0
WLSH1_k127_8765000_37 Pfam:DUF59 - - - 0.0000000000000000003791 90.0
WLSH1_k127_8765000_38 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000003987 88.0
WLSH1_k127_8765000_39 Beta-lactamase enzyme family K01467,K17836 - 3.5.2.6 0.000000000000000000557 100.0
WLSH1_k127_8765000_4 Dehydratase family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 613.0
WLSH1_k127_8765000_40 PAP2 superfamily - - - 0.0000000000000000136 93.0
WLSH1_k127_8765000_41 Protein of unknown function (DUF835) - - - 0.0000000000000001235 93.0
WLSH1_k127_8765000_42 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000002583 88.0
WLSH1_k127_8765000_43 PAS domain K02488 - 2.7.7.65 0.000000000000001048 84.0
WLSH1_k127_8765000_44 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000003804 74.0
WLSH1_k127_8765000_45 TIGRFAM MoaD family protein K03636 - - 0.000000004104 62.0
WLSH1_k127_8765000_5 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 565.0
WLSH1_k127_8765000_6 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 449.0
WLSH1_k127_8765000_7 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 403.0
WLSH1_k127_8765000_8 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 356.0
WLSH1_k127_8765000_9 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 319.0
WLSH1_k127_8795110_0 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 436.0
WLSH1_k127_8795110_1 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 399.0
WLSH1_k127_8795110_10 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000005836 189.0
WLSH1_k127_8795110_11 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000007125 204.0
WLSH1_k127_8795110_12 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000002363 139.0
WLSH1_k127_8795110_13 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000003059 123.0
WLSH1_k127_8795110_14 Belongs to the UPF0248 family K09715 - - 0.0000000000000000000001198 99.0
WLSH1_k127_8795110_15 EamA-like transporter family K08978 - - 0.0000000000000004211 88.0
WLSH1_k127_8795110_16 - - - - 0.000000000001793 72.0
WLSH1_k127_8795110_17 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0001124 53.0
WLSH1_k127_8795110_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 289.0
WLSH1_k127_8795110_3 Domain of unknown function (DUF4910) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001017 297.0
WLSH1_k127_8795110_4 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001865 276.0
WLSH1_k127_8795110_5 Phosphohydrolase K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007089 257.0
WLSH1_k127_8795110_6 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000000000000000000000006128 217.0
WLSH1_k127_8795110_7 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000001718 228.0
WLSH1_k127_8795110_8 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000004308 212.0
WLSH1_k127_8795110_9 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.0000000000000000000000000000000000000000000000000000005086 198.0
WLSH1_k127_8906714_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 511.0
WLSH1_k127_8906714_1 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 312.0
WLSH1_k127_8906714_10 Transcriptional regulator - - - 0.00000000000008173 79.0
WLSH1_k127_8906714_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000258 285.0
WLSH1_k127_8906714_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002251 274.0
WLSH1_k127_8906714_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002991 271.0
WLSH1_k127_8906714_5 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003265 267.0
WLSH1_k127_8906714_6 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000005602 254.0
WLSH1_k127_8906714_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000003655 164.0
WLSH1_k127_8906714_8 - - - - 0.0000000000000000000000000000000000000000927 169.0
WLSH1_k127_8906714_9 - - - - 0.000000000000000000000000000000000006962 143.0
WLSH1_k127_8921380_0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 3.411e-229 760.0
WLSH1_k127_8921380_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 605.0
WLSH1_k127_8921380_2 CO dehydrogenase acetyl-CoA synthase K00194 - 2.1.1.245 0.0000000003574 62.0
WLSH1_k127_9110233_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.163e-249 798.0
WLSH1_k127_9110233_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K02192,K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363 1.6.3.4,1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 312.0
WLSH1_k127_9110233_2 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000001386 158.0
WLSH1_k127_9110233_3 VIT family - - - 0.0000000000000000000000000000000001276 140.0
WLSH1_k127_9110233_4 Ribbon-helix-helix protein, copG family K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000001038 115.0
WLSH1_k127_9110233_5 Double zinc ribbon - - - 0.0005093 50.0
WLSH1_k127_9118709_0 helicase superfamily c-terminal domain K03724 - - 6.247e-292 926.0
WLSH1_k127_9118709_1 Type II/IV secretion system protein K07332 - - 6.558e-226 713.0
WLSH1_k127_9118709_10 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000025 280.0
WLSH1_k127_9118709_11 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001727 268.0
WLSH1_k127_9118709_12 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000004466 239.0
WLSH1_k127_9118709_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000006721 202.0
WLSH1_k127_9118709_14 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.00000000000000000000000000000000000000000000000000000002436 203.0
WLSH1_k127_9118709_15 Protein of unknown function (DUF531) K09725 - - 0.000000000000000000000000000000000000000000000000000002193 196.0
WLSH1_k127_9118709_16 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000000000001511 167.0
WLSH1_k127_9118709_17 sodium:proton antiporter activity K05564,K11105 - - 0.0000000000000000000000000000000000000001911 166.0
WLSH1_k127_9118709_18 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000002761 136.0
WLSH1_k127_9118709_19 - - - - 0.00000000000000000000000006644 112.0
WLSH1_k127_9118709_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 623.0
WLSH1_k127_9118709_20 toxin activity - - - 0.00000000000000000002364 102.0
WLSH1_k127_9118709_21 - - - - 0.0000000000000007321 87.0
WLSH1_k127_9118709_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 535.0
WLSH1_k127_9118709_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 482.0
WLSH1_k127_9118709_5 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 447.0
WLSH1_k127_9118709_6 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 415.0
WLSH1_k127_9118709_7 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 400.0
WLSH1_k127_9118709_8 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 343.0
WLSH1_k127_9118709_9 PFAM Pyruvate carboxyltransferase K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 315.0
WLSH1_k127_918744_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.386e-262 842.0
WLSH1_k127_918744_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 499.0
WLSH1_k127_918744_2 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 410.0
WLSH1_k127_918744_3 Peptidase M14, carboxypeptidase A K05996 - 3.4.17.18 0.00000000000000000000000000000000000000000000000000000000002462 227.0
WLSH1_k127_918744_4 PFAM HD domain K03698 - - 0.000000000000000000000000000000000000000000000002094 191.0
WLSH1_k127_918744_5 CHAT domain - - - 0.00000000000000000000000000000000000000000000002992 192.0
WLSH1_k127_918744_6 Uncharacterised protein family (UPF0179) K09730 - - 0.00000000000000000000000000000000001408 139.0
WLSH1_k127_918744_7 Response regulator receiver domain - - - 0.0000000000000000000000000732 114.0
WLSH1_k127_918744_8 DNA-binding transcription factor activity K18297 - - 0.00000000000000000000008298 108.0
WLSH1_k127_918744_9 PFAM molybdopterin biosynthesis MoaE protein K03635,K21142 - 2.8.1.12 0.000000000000007078 77.0
WLSH1_k127_9354469_0 helicase superfamily c-terminal domain K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004006 260.0
WLSH1_k127_9354469_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000000000004982 82.0
WLSH1_k127_9365449_0 Subtilase family K13274,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000007124 261.0
WLSH1_k127_9365449_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000005242 89.0
WLSH1_k127_9414155_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 458.0
WLSH1_k127_9414155_1 Peptidase S8 and S53 subtilisin kexin sedolisin K01342,K14645 - 3.4.21.62 0.00000000000000000000000000000000000000000000000000000000000000000001257 259.0
WLSH1_k127_9414155_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000004699 173.0
WLSH1_k127_9414155_3 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000000001502 145.0
WLSH1_k127_9414155_4 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.0000000000000000000002158 100.0
WLSH1_k127_9414155_5 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.0000000000002525 79.0
WLSH1_k127_9414155_6 self proteolysis - - - 0.000001473 59.0
WLSH1_k127_961521_0 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 496.0
WLSH1_k127_961521_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000426 116.0
WLSH1_k127_9805704_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 580.0
WLSH1_k127_9805704_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 547.0
WLSH1_k127_9805704_10 Methionine synthase K00549 - 2.1.1.14 0.000000000000000002118 98.0
WLSH1_k127_9805704_11 PFAM PKD domain containing protein - - - 0.00000000000000009396 96.0
WLSH1_k127_9805704_12 FR47-like protein K03789 - 2.3.1.128 0.0007437 51.0
WLSH1_k127_9805704_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 494.0
WLSH1_k127_9805704_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 379.0
WLSH1_k127_9805704_4 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001832 252.0
WLSH1_k127_9805704_5 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000168 209.0
WLSH1_k127_9805704_6 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000008005 211.0
WLSH1_k127_9805704_7 - - - - 0.0000000000000000000000000000000000000000000000000009515 192.0
WLSH1_k127_9805704_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000001406 190.0
WLSH1_k127_9805704_9 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000001327 179.0