Overview

ID MAG04189
Name WLSH1_bin.6
Sample SMP0109
Taxonomy
Kingdom Bacteria
Phylum Omnitrophota
Class Koll11
Order Gygaellales
Family Profunditerraquicolaceae
Genus UBA6249
Species
Assembly information
Completeness (%) 96.79
Contamination (%) 0.82
GC content (%) 42.0
N50 (bp) 13,759
Genome size (bp) 1,298,683

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1263

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH1_k127_10008504_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 497.0
WLSH1_k127_10008504_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 366.0
WLSH1_k127_10008504_10 Yqey-like protein K09117 - - 0.0000000000000000000000003186 111.0
WLSH1_k127_10008504_11 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000003106 103.0
WLSH1_k127_10008504_12 Asparagine synthase K06864 - - 0.0000000001244 62.0
WLSH1_k127_10008504_2 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 361.0
WLSH1_k127_10008504_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 354.0
WLSH1_k127_10008504_4 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 313.0
WLSH1_k127_10008504_5 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 302.0
WLSH1_k127_10008504_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005147 286.0
WLSH1_k127_10008504_7 TonB-dependent receptor plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000002385 251.0
WLSH1_k127_10008504_8 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000007131 166.0
WLSH1_k127_10008504_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000004216 138.0
WLSH1_k127_10129139_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 527.0
WLSH1_k127_10129139_1 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 541.0
WLSH1_k127_10129139_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000005954 74.0
WLSH1_k127_10129139_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 380.0
WLSH1_k127_10129139_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000004796 219.0
WLSH1_k127_10129139_4 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000003665 147.0
WLSH1_k127_10129139_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000117 139.0
WLSH1_k127_10129139_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000004388 135.0
WLSH1_k127_10129139_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000006488 109.0
WLSH1_k127_10129139_8 Helix-turn-helix domain - - - 0.000000000000000000008467 102.0
WLSH1_k127_10129139_9 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000002489 71.0
WLSH1_k127_10149300_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 360.0
WLSH1_k127_10149300_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 301.0
WLSH1_k127_10149300_2 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000128 153.0
WLSH1_k127_10316319_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 600.0
WLSH1_k127_10316319_1 recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 312.0
WLSH1_k127_10316319_2 CBS domain containing protein K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002545 286.0
WLSH1_k127_10316319_3 riboflavin biosynthesis protein K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000004983 227.0
WLSH1_k127_10316319_4 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000001425 227.0
WLSH1_k127_10316319_5 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000001148 186.0
WLSH1_k127_10316319_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000005277 117.0
WLSH1_k127_10316319_7 Acylphosphatase K01512 - 3.6.1.7 0.000392 44.0
WLSH1_k127_10324918_0 4Fe-4S single cluster domain - - - 0.000000000000000000000000002316 115.0
WLSH1_k127_10324918_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000001542 61.0
WLSH1_k127_10340094_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 375.0
WLSH1_k127_10340094_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 295.0
WLSH1_k127_10340094_2 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000005459 228.0
WLSH1_k127_10340094_3 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000287 219.0
WLSH1_k127_10340094_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000007621 83.0
WLSH1_k127_10340094_5 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000000131 78.0
WLSH1_k127_10394681_0 Glycosyltransferase 36 associated - - - 1.476e-271 866.0
WLSH1_k127_10394681_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000001475 94.0
WLSH1_k127_10398681_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003078 278.0
WLSH1_k127_10398681_1 general secretion pathway protein K02453 - - 0.00000000000000000007198 97.0
WLSH1_k127_10625371_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001607 242.0
WLSH1_k127_10625371_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000166 160.0
WLSH1_k127_10670271_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009612 445.0
WLSH1_k127_10670271_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 420.0
WLSH1_k127_10670271_10 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000067 178.0
WLSH1_k127_10670271_11 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000001844 176.0
WLSH1_k127_10670271_12 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000001542 139.0
WLSH1_k127_10670271_13 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000002604 137.0
WLSH1_k127_10670271_14 Transposase IS200 like - - - 0.0000000000000000000000000000009701 137.0
WLSH1_k127_10670271_15 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000001433 130.0
WLSH1_k127_10670271_16 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000001431 123.0
WLSH1_k127_10670271_17 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000134 122.0
WLSH1_k127_10670271_18 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000001368 115.0
WLSH1_k127_10670271_19 cheY-homologous receiver domain K02490 - - 0.000000000000000002654 89.0
WLSH1_k127_10670271_2 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002349 274.0
WLSH1_k127_10670271_20 - - - - 0.000000000001031 81.0
WLSH1_k127_10670271_21 - - - - 0.00000000001005 70.0
WLSH1_k127_10670271_23 GDSL-like lipase acylhydrolase - - - 0.00000002306 66.0
WLSH1_k127_10670271_24 Transcriptional regulator K11923 - - 0.0004488 47.0
WLSH1_k127_10670271_25 Tetratricopeptide repeat - - - 0.0005037 51.0
WLSH1_k127_10670271_3 Elongator protein 3, MiaB family, Radical SAM K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000005196 263.0
WLSH1_k127_10670271_4 Histidine kinase K11383 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000003138 235.0
WLSH1_k127_10670271_5 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000341 232.0
WLSH1_k127_10670271_6 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000004357 226.0
WLSH1_k127_10670271_7 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000006401 218.0
WLSH1_k127_10670271_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000006112 205.0
WLSH1_k127_10670271_9 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000004523 176.0
WLSH1_k127_10692117_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000003667 214.0
WLSH1_k127_10692117_1 MutS protein K08740 GO:0000003,GO:0000228,GO:0000280,GO:0000793,GO:0000794,GO:0000795,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007059,GO:0007127,GO:0007129,GO:0007131,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0022414,GO:0022607,GO:0030983,GO:0031974,GO:0031981,GO:0033554,GO:0034641,GO:0035825,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045132,GO:0045143,GO:0046483,GO:0048285,GO:0050896,GO:0051026,GO:0051276,GO:0051321,GO:0051716,GO:0061982,GO:0070013,GO:0070192,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0098813,GO:0099086,GO:0140013,GO:1901360,GO:1901363,GO:1903046 - 0.000000008106 68.0
WLSH1_k127_10757444_0 PFAM glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 7.238e-197 624.0
WLSH1_k127_10757444_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 535.0
WLSH1_k127_10757444_2 PFAM glycine cleavage T protein (aminomethyl transferase) K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002162 285.0
WLSH1_k127_10757444_3 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.00000000000000000000000000000000000009586 145.0
WLSH1_k127_1079877_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 477.0
WLSH1_k127_1079877_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 465.0
WLSH1_k127_1079877_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000002701 202.0
WLSH1_k127_1079877_3 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000002735 172.0
WLSH1_k127_1079877_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000002574 154.0
WLSH1_k127_1079877_5 PFAM peptidase - - - 0.00000000000000000000000000007874 124.0
WLSH1_k127_1079877_6 Protein conserved in bacteria - - - 0.0000000009595 64.0
WLSH1_k127_1079877_7 ATPase, AAA superfamily K06921 - - 0.000004343 60.0
WLSH1_k127_1079877_8 - - - - 0.0003196 46.0
WLSH1_k127_10893227_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 503.0
WLSH1_k127_10893227_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 303.0
WLSH1_k127_10893227_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001507 266.0
WLSH1_k127_11006199_0 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 454.0
WLSH1_k127_11006199_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000001649 144.0
WLSH1_k127_11006199_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000002209 127.0
WLSH1_k127_11006199_4 Flavodoxin - - - 0.000000000000000000001795 102.0
WLSH1_k127_11006199_5 UV-endonuclease UvdE K13281 - - 0.0000000000582 64.0
WLSH1_k127_11006199_6 PFAM Uncharacterised protein domain Spy-rel - - - 0.000002364 55.0
WLSH1_k127_11006199_7 Domain of unknown function (DUF4349) - - - 0.0000764 51.0
WLSH1_k127_1169750_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 513.0
WLSH1_k127_1169750_1 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 300.0
WLSH1_k127_1169750_2 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - 0.000000000000000000000000000000000000000000000000000000000000000828 226.0
WLSH1_k127_1169750_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000002882 170.0
WLSH1_k127_1169750_4 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000003897 149.0
WLSH1_k127_1186417_0 radical SAM domain protein - - - 0.0000000000000000000000000000004141 128.0
WLSH1_k127_1186417_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000002036 126.0
WLSH1_k127_1186417_2 PFAM Conserved TM helix - - - 0.0000000000000000000000000001951 123.0
WLSH1_k127_1186417_3 YacP-like NYN domain - - - 0.0003282 49.0
WLSH1_k127_1188566_0 Heat shock 70 kDa protein K04043 - - 2.522e-252 792.0
WLSH1_k127_1188566_1 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 499.0
WLSH1_k127_1188566_10 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000002333 218.0
WLSH1_k127_1188566_11 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000004289 213.0
WLSH1_k127_1188566_12 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0000000000000000000000000000000000000000004477 180.0
WLSH1_k127_1188566_13 diguanylate cyclase K21022 - 2.7.7.65 0.000000000000000000000000000000000000000004866 170.0
WLSH1_k127_1188566_14 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000547 167.0
WLSH1_k127_1188566_15 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000003681 146.0
WLSH1_k127_1188566_16 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000002281 130.0
WLSH1_k127_1188566_17 FmdB family - - - 0.00000000000000011 82.0
WLSH1_k127_1188566_18 MerR HTH family regulatory protein K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000004857 57.0
WLSH1_k127_1188566_19 Sporulation related domain K01448 - 3.5.1.28 0.000007716 56.0
WLSH1_k127_1188566_2 ABC transporter K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 460.0
WLSH1_k127_1188566_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008463 352.0
WLSH1_k127_1188566_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 345.0
WLSH1_k127_1188566_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 332.0
WLSH1_k127_1188566_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 288.0
WLSH1_k127_1188566_7 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003475 291.0
WLSH1_k127_1188566_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000002371 255.0
WLSH1_k127_1188566_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000004079 230.0
WLSH1_k127_1267069_0 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 535.0
WLSH1_k127_1267069_1 type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 531.0
WLSH1_k127_1267069_2 type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000429 276.0
WLSH1_k127_1267069_3 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000000003954 118.0
WLSH1_k127_1267069_4 Sensor diguanylate cyclase, GAF domain-containing - - - 0.000000000000000000000000001376 128.0
WLSH1_k127_145253_0 neurotransmitter:sodium symporter activity K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 554.0
WLSH1_k127_145253_1 Patatin-like phospholipase K01999,K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001476 269.0
WLSH1_k127_145253_2 Mazg nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000001376 118.0
WLSH1_k127_145253_3 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000006991 115.0
WLSH1_k127_145253_5 PFAM alpha beta hydrolase fold - - - 0.00001206 47.0
WLSH1_k127_1524461_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.458e-297 927.0
WLSH1_k127_1524461_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.63e-258 808.0
WLSH1_k127_1524461_10 DRTGG domain K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 338.0
WLSH1_k127_1524461_11 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 314.0
WLSH1_k127_1524461_12 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 318.0
WLSH1_k127_1524461_13 PFAM Phosphate acetyl butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009322 282.0
WLSH1_k127_1524461_14 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008724 264.0
WLSH1_k127_1524461_15 methyltransferase K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000005605 236.0
WLSH1_k127_1524461_16 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000257 221.0
WLSH1_k127_1524461_17 Nitroreductase family - - - 0.0000000000000000000000000000000000000000003584 163.0
WLSH1_k127_1524461_18 CHAT domain - - - 0.0000000000000000000000000000000000000000008893 179.0
WLSH1_k127_1524461_19 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0016485,GO:0016540,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564 4.1.1.11 0.000000000000000000000000000000000000000007688 156.0
WLSH1_k127_1524461_2 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.318e-237 738.0
WLSH1_k127_1524461_20 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000008356 157.0
WLSH1_k127_1524461_21 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000009896 150.0
WLSH1_k127_1524461_22 Thioredoxin K03671 - - 0.000000000000000000000000000000000000135 143.0
WLSH1_k127_1524461_23 Transcriptional regulator K13643 - - 0.00000000000000000000000000000004912 129.0
WLSH1_k127_1524461_24 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000001314 115.0
WLSH1_k127_1524461_25 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000001185 100.0
WLSH1_k127_1524461_26 Histidine kinase - - - 0.0000000000000000002102 104.0
WLSH1_k127_1524461_27 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000002871 70.0
WLSH1_k127_1524461_28 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000002134 75.0
WLSH1_k127_1524461_29 Sortilin, neurotensin receptor 3, - - - 0.00000000002505 76.0
WLSH1_k127_1524461_3 Ferrous iron transport protein B K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 591.0
WLSH1_k127_1524461_30 FeoA K04758 - - 0.00000000346 61.0
WLSH1_k127_1524461_31 Belongs to the 'phage' integrase family - - - 0.0005693 43.0
WLSH1_k127_1524461_32 Belongs to the 'phage' integrase family - - - 0.0006291 42.0
WLSH1_k127_1524461_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 572.0
WLSH1_k127_1524461_5 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 458.0
WLSH1_k127_1524461_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 417.0
WLSH1_k127_1524461_7 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 387.0
WLSH1_k127_1524461_8 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 360.0
WLSH1_k127_1524461_9 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 339.0
WLSH1_k127_1647078_0 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 327.0
WLSH1_k127_1647078_1 Type II secretory pathway component ExeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 298.0
WLSH1_k127_1647078_10 Psort location Cytoplasmic, score 8.87 - - - 0.000003437 59.0
WLSH1_k127_1647078_11 4Fe-4S single cluster domain - - - 0.00001125 51.0
WLSH1_k127_1647078_12 Uncharacterised nucleotidyltransferase - - - 0.00001759 57.0
WLSH1_k127_1647078_2 protein involved in exopolysaccharide biosynthesis K16692 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001497 278.0
WLSH1_k127_1647078_3 O-Antigen ligase K02847,K13009 - - 0.0000000000000000000000000000000000000000000000000000000000003017 228.0
WLSH1_k127_1647078_4 Domain of unknown function (DUF3391) - - - 0.000000000000000000000000000000000002065 152.0
WLSH1_k127_1647078_5 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000001933 124.0
WLSH1_k127_1647078_6 polysaccharide K01991,K20987 - - 0.0000000000000000000000001888 120.0
WLSH1_k127_1647078_7 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000287 73.0
WLSH1_k127_1647078_8 polysaccharide export K01991 - - 0.00000004196 65.0
WLSH1_k127_1647078_9 ABC transporter K06147 - - 0.000002772 51.0
WLSH1_k127_1678903_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 565.0
WLSH1_k127_1678903_1 PFAM TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001343 287.0
WLSH1_k127_1678903_10 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.000000000000003944 76.0
WLSH1_k127_1678903_11 Domain of unknown function (DUF1844) - - - 0.0000000000001637 75.0
WLSH1_k127_1678903_12 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000007668 58.0
WLSH1_k127_1678903_13 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0001582 52.0
WLSH1_k127_1678903_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000008164 273.0
WLSH1_k127_1678903_3 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001696 250.0
WLSH1_k127_1678903_4 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000001274 226.0
WLSH1_k127_1678903_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000001933 219.0
WLSH1_k127_1678903_6 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000001813 166.0
WLSH1_k127_1678903_7 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000000005125 144.0
WLSH1_k127_1678903_8 - - - - 0.0000000000000000000000000000007182 128.0
WLSH1_k127_1678903_9 Asp23 family, cell envelope-related function - - - 0.000000000000000001005 89.0
WLSH1_k127_1747567_0 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000003422 102.0
WLSH1_k127_1747567_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000002083 78.0
WLSH1_k127_2018992_0 UV-endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 362.0
WLSH1_k127_2018992_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006206 273.0
WLSH1_k127_2020935_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 378.0
WLSH1_k127_2020935_1 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00000000000000000000000000001648 120.0
WLSH1_k127_2020935_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000004403 125.0
WLSH1_k127_2027936_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 513.0
WLSH1_k127_2027936_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 475.0
WLSH1_k127_2027936_10 transferase activity, transferring glycosyl groups K00786 - - 0.0000000000000000000002402 99.0
WLSH1_k127_2027936_11 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000711 72.0
WLSH1_k127_2027936_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 369.0
WLSH1_k127_2027936_3 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 330.0
WLSH1_k127_2027936_4 Aminotransferase K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004518 280.0
WLSH1_k127_2027936_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007734 279.0
WLSH1_k127_2027936_6 PFAM Glycosyltransferase family 28 C-terminal domain K03429 - 2.4.1.315 0.000000000000000000000000000000000000000000000000000000000000000000000000002017 267.0
WLSH1_k127_2027936_7 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000009377 224.0
WLSH1_k127_2027936_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000003901 200.0
WLSH1_k127_2027936_9 Lipid A biosynthesis K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.000000000000000000000000000000000001012 149.0
WLSH1_k127_2099712_0 Chaperone - - - 0.000000000000002458 86.0
WLSH1_k127_210441_0 Bacterial DNA topoisomeraes I ATP-binding domain K03168 - 5.99.1.2 9.297e-196 630.0
WLSH1_k127_210441_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 357.0
WLSH1_k127_210441_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 290.0
WLSH1_k127_210441_3 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000006015 218.0
WLSH1_k127_210441_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000009896 150.0
WLSH1_k127_210441_5 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000000000000000389 141.0
WLSH1_k127_210441_6 Could be involved in septation K06412 - - 0.00000000001378 67.0
WLSH1_k127_2146233_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 519.0
WLSH1_k127_2146233_1 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 428.0
WLSH1_k127_2146233_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000003664 170.0
WLSH1_k127_2146233_3 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000005775 147.0
WLSH1_k127_2146233_4 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001854 145.0
WLSH1_k127_2146233_5 rRNA binding K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001431 85.0
WLSH1_k127_2146233_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000004557 69.0
WLSH1_k127_2204825_0 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 468.0
WLSH1_k127_2204825_1 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 392.0
WLSH1_k127_2204825_2 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 390.0
WLSH1_k127_2204825_3 belongs to the phosphoglycerate kinase family K00927,K01803 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 369.0
WLSH1_k127_2204825_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001825 269.0
WLSH1_k127_2204825_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008333 265.0
WLSH1_k127_2204825_6 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000006005 207.0
WLSH1_k127_2204825_7 Monogalactosyldiacylglycerol synthase K03429,K03715 - 2.4.1.315,2.4.1.46 0.00000000000000000000000000000000000000000000000000001507 202.0
WLSH1_k127_2204825_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000001413 188.0
WLSH1_k127_2204825_9 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000003236 152.0
WLSH1_k127_2237205_0 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 315.0
WLSH1_k127_2237205_1 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000009131 170.0
WLSH1_k127_2237205_2 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.0000000000000004998 82.0
WLSH1_k127_235349_0 Amidohydrolase K07045 - - 0.00000000000000000000397 104.0
WLSH1_k127_235349_1 hydrolase, family 3 K05349 - 3.2.1.21 0.0000000000001582 78.0
WLSH1_k127_235349_2 Phosphorylase superfamily K00757 - 2.4.2.3 0.0003798 44.0
WLSH1_k127_239816_0 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 416.0
WLSH1_k127_239816_1 actin binding K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001146 283.0
WLSH1_k127_239816_2 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009971 277.0
WLSH1_k127_239816_3 PFAM zinc iron permease K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001986 246.0
WLSH1_k127_239816_4 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000007314 130.0
WLSH1_k127_239816_5 BioY family K03523 - - 0.0000000000000000000000001386 114.0
WLSH1_k127_239816_6 Curli production assembly/transport component CsgG - - - 0.0000000002917 69.0
WLSH1_k127_2425487_0 Carbamoyltransferase C-terminus K00612 - - 2.266e-215 683.0
WLSH1_k127_2425487_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000008598 147.0
WLSH1_k127_2425487_2 Radical SAM superfamily - - - 0.000000000000000000000000000002643 131.0
WLSH1_k127_254501_0 PFAM Carbon starvation protein CstA K06200 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0008150,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 336.0
WLSH1_k127_254501_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000008903 158.0
WLSH1_k127_254501_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000003843 64.0
WLSH1_k127_254501_3 - - - - 0.0000000006438 64.0
WLSH1_k127_2594358_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001627 254.0
WLSH1_k127_2594358_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006125 249.0
WLSH1_k127_2594358_2 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000115 214.0
WLSH1_k127_2594358_3 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000007169 181.0
WLSH1_k127_2594429_0 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 380.0
WLSH1_k127_2594429_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000003765 161.0
WLSH1_k127_2594429_2 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.0000000123 64.0
WLSH1_k127_2722174_0 Type II secretion system K12511 - - 0.000000000000000000000000000009395 123.0
WLSH1_k127_2722174_1 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000001262 105.0
WLSH1_k127_2722174_2 PFAM Integrase catalytic region K07497 - - 0.00004649 48.0
WLSH1_k127_2722988_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 3.333e-316 995.0
WLSH1_k127_2722988_1 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 9.149e-310 968.0
WLSH1_k127_2722988_10 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000002318 153.0
WLSH1_k127_2722988_11 cell envelope organization K05807,K08309 - - 0.00000000000000000000000000001098 130.0
WLSH1_k127_2722988_12 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000213 94.0
WLSH1_k127_2722988_13 methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000000003146 91.0
WLSH1_k127_2722988_14 DNA uptake protein and related DNA-binding proteins K02237 - - 0.0000001131 57.0
WLSH1_k127_2722988_15 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000004386 55.0
WLSH1_k127_2722988_16 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.00000817 51.0
WLSH1_k127_2722988_17 Lipopolysaccharide-assembly - - - 0.000009512 55.0
WLSH1_k127_2722988_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 388.0
WLSH1_k127_2722988_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 333.0
WLSH1_k127_2722988_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 312.0
WLSH1_k127_2722988_5 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 306.0
WLSH1_k127_2722988_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 295.0
WLSH1_k127_2722988_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000004078 235.0
WLSH1_k127_2722988_8 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000003598 221.0
WLSH1_k127_2722988_9 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000002678 172.0
WLSH1_k127_2763955_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 351.0
WLSH1_k127_2763955_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 298.0
WLSH1_k127_2763955_2 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000003441 205.0
WLSH1_k127_2763955_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000001724 176.0
WLSH1_k127_2763955_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000009848 61.0
WLSH1_k127_2867240_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 502.0
WLSH1_k127_2867240_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 301.0
WLSH1_k127_2867240_2 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000819 213.0
WLSH1_k127_2867240_3 MlaD protein K02067 - - 0.00000000000000000006348 97.0
WLSH1_k127_3005023_0 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 344.0
WLSH1_k127_3005023_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001625 276.0
WLSH1_k127_3005023_10 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000009195 132.0
WLSH1_k127_3005023_11 DoxX K15977 - - 0.00000000000000000000000175 107.0
WLSH1_k127_3005023_12 lycopene cyclase - - - 0.0000000000000000008274 89.0
WLSH1_k127_3005023_13 lycopene cyclase - - - 0.000000000000000002126 88.0
WLSH1_k127_3005023_15 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000001388 82.0
WLSH1_k127_3005023_16 Peptidase MA superfamily - - - 0.000000000001481 78.0
WLSH1_k127_3005023_17 Type IV pilus assembly protein PilM K02662 - - 0.00000000000897 78.0
WLSH1_k127_3005023_18 TIGRFAM PEP-CTERM system TPR-repeat lipoprotein - - - 0.000000008525 66.0
WLSH1_k127_3005023_19 Type II secretion system (T2SS), protein J K02459 - - 0.0006139 49.0
WLSH1_k127_3005023_2 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002661 261.0
WLSH1_k127_3005023_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000001565 243.0
WLSH1_k127_3005023_4 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000663 220.0
WLSH1_k127_3005023_5 ergosterol biosynthetic process K00801,K02291,K10208 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000005853 217.0
WLSH1_k127_3005023_6 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000006407 182.0
WLSH1_k127_3005023_7 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000002427 160.0
WLSH1_k127_3005023_8 Cytochrome C biogenesis protein - - - 0.0000000000000000000000000000000006897 145.0
WLSH1_k127_3005023_9 General Secretion Pathway protein K02456 - - 0.0000000000000000000000000000009128 126.0
WLSH1_k127_3166419_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1159.0
WLSH1_k127_3166419_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 464.0
WLSH1_k127_3166419_10 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.000000000000000000007342 109.0
WLSH1_k127_3166419_11 Excisionase - - - 0.00000000004237 65.0
WLSH1_k127_3166419_12 Winged helix-turn-helix domain (DUF2582) - - - 0.00000002369 57.0
WLSH1_k127_3166419_13 Bacterial membrane protein, YfhO - - - 0.000001624 60.0
WLSH1_k127_3166419_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 395.0
WLSH1_k127_3166419_3 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 355.0
WLSH1_k127_3166419_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 310.0
WLSH1_k127_3166419_5 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 305.0
WLSH1_k127_3166419_6 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008591 274.0
WLSH1_k127_3166419_7 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006585 261.0
WLSH1_k127_3166419_8 Predicted membrane protein (DUF2079) K07778 - 2.7.13.3 0.00000000000000000000001256 117.0
WLSH1_k127_3166419_9 Glycosyl transferase family 2 - - - 0.000000000000000000001788 104.0
WLSH1_k127_3170760_0 PFAM binding-protein-dependent transport systems inner membrane component K02026,K10119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 293.0
WLSH1_k127_3170760_1 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007231 252.0
WLSH1_k127_3170760_2 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003794 252.0
WLSH1_k127_3170760_3 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000002141 203.0
WLSH1_k127_3170760_4 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.0000000000000000000000000001354 129.0
WLSH1_k127_3170760_5 beta-galactosidase activity K01224 - 3.2.1.89 0.0000000000000000000000003406 115.0
WLSH1_k127_3170760_6 beta-galactosidase activity - - - 0.0000000000000000000003977 109.0
WLSH1_k127_3170760_7 - - - - 0.00000000000001154 88.0
WLSH1_k127_3207519_0 protein (ATP-grasp superfamily) K07159 - - 0.0000000000000000000000000000000000000000000109 175.0
WLSH1_k127_3207519_1 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.0000000000000000000000000000001483 132.0
WLSH1_k127_3207519_2 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000005449 93.0
WLSH1_k127_3207519_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000276 54.0
WLSH1_k127_3222889_0 Dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 449.0
WLSH1_k127_3222889_1 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000001205 200.0
WLSH1_k127_3222889_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000006825 126.0
WLSH1_k127_3252829_1 NeuB family K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006466 276.0
WLSH1_k127_3252829_10 radical SAM domain protein - - - 0.00003602 48.0
WLSH1_k127_3252829_11 Phage integrase family - - - 0.00007671 46.0
WLSH1_k127_3252829_12 PFAM Integrase catalytic region K07497 - - 0.0003341 44.0
WLSH1_k127_3252829_2 3-deoxy-manno-octulosonate-8-phosphatase activity K00983,K03270 - 2.7.7.43,3.1.3.45 0.0000000000000000000000000000000000000000000000000004335 193.0
WLSH1_k127_3252829_3 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000002543 164.0
WLSH1_k127_3252829_4 regulation of single-species biofilm formation K02342,K03763,K13573 - 2.7.7.7 0.000000000000000000000000000000005082 138.0
WLSH1_k127_3252829_5 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000002951 129.0
WLSH1_k127_3252829_6 Uncharacterised conserved protein (DUF2156) K01163,K06940 - - 0.00000000000000005296 87.0
WLSH1_k127_3252829_7 Belongs to the 'phage' integrase family - - - 0.00000000000000005637 81.0
WLSH1_k127_3252829_8 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.00000000000002862 86.0
WLSH1_k127_3252829_9 Iron-sulfur cluster-binding domain - - - 0.000000000597 64.0
WLSH1_k127_3259807_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000004919 201.0
WLSH1_k127_3259807_1 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 0.00000000000000000000000000000000001718 147.0
WLSH1_k127_3259807_2 Iron-sulfur cluster-binding domain - - - 0.00000000000000000002993 103.0
WLSH1_k127_3259807_3 SPTR Glycosyl transferase group 1 - - - 0.0000000000002607 82.0
WLSH1_k127_3288079_0 type IV pilus secretin PilQ K02666 - - 0.0000000000000000006423 98.0
WLSH1_k127_3288079_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000001238 74.0
WLSH1_k127_3415086_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 3.68e-238 747.0
WLSH1_k127_3415086_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 570.0
WLSH1_k127_3442649_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1338.0
WLSH1_k127_3442649_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.019e-237 747.0
WLSH1_k127_3442649_10 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000086 250.0
WLSH1_k127_3442649_11 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000001081 249.0
WLSH1_k127_3442649_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000003053 235.0
WLSH1_k127_3442649_13 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000001221 233.0
WLSH1_k127_3442649_14 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000001477 237.0
WLSH1_k127_3442649_15 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000000000000000001321 221.0
WLSH1_k127_3442649_16 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000002444 195.0
WLSH1_k127_3442649_17 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000001786 190.0
WLSH1_k127_3442649_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000005509 179.0
WLSH1_k127_3442649_19 ATP synthase subunit K K02124 - - 0.00000000000000000000000000000000000000001086 158.0
WLSH1_k127_3442649_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.437e-213 681.0
WLSH1_k127_3442649_20 membrane protein (DUF2079) - - - 0.000000000000000000000003129 117.0
WLSH1_k127_3442649_21 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000001114 102.0
WLSH1_k127_3442649_22 Protein of unknown function (DUF2764) - - - 0.00000000000000000004338 96.0
WLSH1_k127_3442649_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 7.825e-213 668.0
WLSH1_k127_3442649_4 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 491.0
WLSH1_k127_3442649_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 391.0
WLSH1_k127_3442649_6 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 379.0
WLSH1_k127_3442649_7 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 327.0
WLSH1_k127_3442649_8 V-type ATP synthase, subunit I K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 328.0
WLSH1_k127_3442649_9 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000001627 245.0
WLSH1_k127_3693891_0 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 536.0
WLSH1_k127_3693891_1 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 302.0
WLSH1_k127_3693891_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000846 117.0
WLSH1_k127_3706647_0 beta-glucosidase activity K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 357.0
WLSH1_k127_3706647_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000003769 89.0
WLSH1_k127_3706647_2 Putative peptidoglycan binding domain - - - 0.000000001142 65.0
WLSH1_k127_3719912_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1084.0
WLSH1_k127_3719912_1 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 582.0
WLSH1_k127_3719912_10 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000018 157.0
WLSH1_k127_3719912_11 COG2406 Protein distantly related to bacterial ferritins K03594 - 1.16.3.1 0.0000000000000000000000009975 109.0
WLSH1_k127_3719912_12 - - - - 0.000000000000000000000001903 107.0
WLSH1_k127_3719912_13 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000004084 101.0
WLSH1_k127_3719912_14 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000001167 96.0
WLSH1_k127_3719912_15 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000008508 82.0
WLSH1_k127_3719912_16 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000001881 66.0
WLSH1_k127_3719912_17 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000003612 66.0
WLSH1_k127_3719912_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 503.0
WLSH1_k127_3719912_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 454.0
WLSH1_k127_3719912_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 394.0
WLSH1_k127_3719912_5 Catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 349.0
WLSH1_k127_3719912_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003096 284.0
WLSH1_k127_3719912_7 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003153 259.0
WLSH1_k127_3719912_8 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000008037 249.0
WLSH1_k127_3719912_9 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172,K18357 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000007614 195.0
WLSH1_k127_3988443_0 methionine synthase K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000001812 246.0
WLSH1_k127_3988443_1 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000002218 182.0
WLSH1_k127_3988443_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000002416 85.0
WLSH1_k127_4044073_0 mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 423.0
WLSH1_k127_4068221_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 6.537e-279 883.0
WLSH1_k127_4068221_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 370.0
WLSH1_k127_4068221_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000001637 60.0
WLSH1_k127_4068221_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 364.0
WLSH1_k127_4068221_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 357.0
WLSH1_k127_4068221_4 Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 342.0
WLSH1_k127_4068221_5 PFAM Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 321.0
WLSH1_k127_4068221_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000004668 189.0
WLSH1_k127_4068221_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000003184 169.0
WLSH1_k127_4068221_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000008931 162.0
WLSH1_k127_4068221_9 Belongs to the SpoVG family K06412 - - 0.0000000000000000000000000003573 118.0
WLSH1_k127_4088426_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.413e-293 920.0
WLSH1_k127_4088426_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 617.0
WLSH1_k127_4088426_2 aspartate kinase, monofunctional class K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 474.0
WLSH1_k127_4088426_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 458.0
WLSH1_k127_4088426_4 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 456.0
WLSH1_k127_4088426_5 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 451.0
WLSH1_k127_4088426_6 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 337.0
WLSH1_k127_4088426_7 Thymidylate synthase K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000007078 173.0
WLSH1_k127_4088426_8 phosphopantothenoylcysteine decarboxylase activity K01598,K13038,K21977 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000006976 121.0
WLSH1_k127_4088426_9 hydrolase K01048 - 3.1.1.5 0.000006434 48.0
WLSH1_k127_4190566_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 8.798e-238 745.0
WLSH1_k127_4190566_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 481.0
WLSH1_k127_4190566_2 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 403.0
WLSH1_k127_4190566_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 359.0
WLSH1_k127_4190566_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 306.0
WLSH1_k127_4190566_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000002592 251.0
WLSH1_k127_4190566_6 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000003079 242.0
WLSH1_k127_4190566_7 Domain of unknown function (DUF4912) K09942 - - 0.000000000000000000000000000000000000000000000000000000008325 210.0
WLSH1_k127_4190566_8 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000008363 163.0
WLSH1_k127_4190566_9 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000001004 141.0
WLSH1_k127_4408412_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 502.0
WLSH1_k127_4408412_1 MarC family integral membrane protein - - - 0.000000000000000000000000000000000000000005481 161.0
WLSH1_k127_4408412_2 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000008557 92.0
WLSH1_k127_4408412_3 BT1 family - GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0008517,GO:0009507,GO:0009526,GO:0009536,GO:0009941,GO:0015075,GO:0015231,GO:0015238,GO:0015318,GO:0015350,GO:0015711,GO:0015849,GO:0015884,GO:0015885,GO:0015893,GO:0022857,GO:0031967,GO:0031975,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0051958,GO:0055085,GO:0071702,GO:0071705,GO:0072337,GO:0072349,GO:0090482,GO:0098656,GO:1903825,GO:1905039 - 0.00000000000000000001685 104.0
WLSH1_k127_4476061_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 292.0
WLSH1_k127_4476061_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000006065 218.0
WLSH1_k127_4476061_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000006298 171.0
WLSH1_k127_4476061_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000002962 146.0
WLSH1_k127_4476061_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000008559 148.0
WLSH1_k127_4476061_5 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000008807 156.0
WLSH1_k127_4476061_6 auxin efflux carrier K07088 - - 0.00000001241 66.0
WLSH1_k127_4483886_0 HD domain - - - 0.00000002635 58.0
WLSH1_k127_4483886_1 PFAM Tetratricopeptide - - - 0.0000002613 61.0
WLSH1_k127_4488629_0 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000002391 241.0
WLSH1_k127_4488629_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000004761 129.0
WLSH1_k127_4508625_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 530.0
WLSH1_k127_4508625_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005384 258.0
WLSH1_k127_4508625_2 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000000001778 88.0
WLSH1_k127_4508625_3 Helix-turn-helix domain - - - 0.000000001028 62.0
WLSH1_k127_4519790_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 421.0
WLSH1_k127_4519790_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 412.0
WLSH1_k127_4519790_2 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 288.0
WLSH1_k127_4519790_3 PFAM metal-dependent phosphohydrolase, HD sub domain K02030,K02103,K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000001554 269.0
WLSH1_k127_4519790_4 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000009207 198.0
WLSH1_k127_4519790_5 epimerase dehydratase K08678 - 4.1.1.35 0.000000000000000000001526 95.0
WLSH1_k127_4720214_0 PFAM Type II secretion system protein E K02283,K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 551.0
WLSH1_k127_4720214_1 PFAM type II and III secretion system protein K02280 - - 0.000000000000000000000000000000000000001871 166.0
WLSH1_k127_4720214_2 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000126 106.0
WLSH1_k127_4720214_3 Peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.000000000000000000000002601 114.0
WLSH1_k127_4720214_4 CAAX protease self-immunity - - - 0.000000000000000000000008796 116.0
WLSH1_k127_4720214_5 COG3745 Flp pilus assembly protein CpaB - - - 0.00000000000001657 84.0
WLSH1_k127_4882234_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 339.0
WLSH1_k127_4882234_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003188 296.0
WLSH1_k127_4882234_10 LmbE homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000008865 224.0
WLSH1_k127_4882234_11 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000002822 238.0
WLSH1_k127_4882234_12 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000002454 228.0
WLSH1_k127_4882234_13 PFAM methyltransferase - - - 0.000000000000000000000000000000000000000000000001557 186.0
WLSH1_k127_4882234_14 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.0000000000000000000000000000000000000000000005593 179.0
WLSH1_k127_4882234_15 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000001084 184.0
WLSH1_k127_4882234_16 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000001188 141.0
WLSH1_k127_4882234_17 Tellurite resistance protein TehB - - - 0.00000000000000000000000000002927 119.0
WLSH1_k127_4882234_18 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000002083 115.0
WLSH1_k127_4882234_19 methyltransferase activity K00563,K02169 - 2.1.1.187,2.1.1.197 0.000000000000000000000000009001 118.0
WLSH1_k127_4882234_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000255 261.0
WLSH1_k127_4882234_20 Glycosyltransferase, group 2 family protein - - - 0.0000000000000267 87.0
WLSH1_k127_4882234_21 Putative methyltransferase - - - 0.0000000003832 69.0
WLSH1_k127_4882234_22 - - - - 0.0000001732 60.0
WLSH1_k127_4882234_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000001194 261.0
WLSH1_k127_4882234_4 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004832 251.0
WLSH1_k127_4882234_5 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000282 249.0
WLSH1_k127_4882234_6 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000005172 237.0
WLSH1_k127_4882234_7 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000007304 243.0
WLSH1_k127_4882234_8 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000001246 245.0
WLSH1_k127_4882234_9 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000001332 228.0
WLSH1_k127_4909035_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000007296 174.0
WLSH1_k127_4909035_1 - - - - 0.00000002863 58.0
WLSH1_k127_4995339_0 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.000000000000000000000000000000000000000000000000000000787 201.0
WLSH1_k127_5017498_0 ABC transporter, ATP-binding protein - - - 6.466e-228 717.0
WLSH1_k127_5017498_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01666 - 4.1.3.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 401.0
WLSH1_k127_5017498_10 membrane transporter protein K07090 - - 0.000000000000000000000000000000003239 131.0
WLSH1_k127_5017498_11 GIY-YIG catalytic domain K07461 - - 0.000000000000000000004107 94.0
WLSH1_k127_5017498_12 - - - - 0.0000000000000008905 78.0
WLSH1_k127_5017498_13 - - - - 0.0000000393 58.0
WLSH1_k127_5017498_14 - - - - 0.0000001415 59.0
WLSH1_k127_5017498_15 Protein of unknown function DUF45 K07043 - - 0.0001872 48.0
WLSH1_k127_5017498_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 321.0
WLSH1_k127_5017498_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K01866,K07304,K07305,K12267 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0016491,GO:0016667,GO:0016671,GO:0020012,GO:0030682,GO:0033744,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0075136 1.8.4.11,1.8.4.12,6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 299.0
WLSH1_k127_5017498_4 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005778 270.0
WLSH1_k127_5017498_5 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001321 255.0
WLSH1_k127_5017498_6 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000003647 185.0
WLSH1_k127_5017498_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000001465 196.0
WLSH1_k127_5017498_8 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000002393 175.0
WLSH1_k127_5017498_9 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000007455 162.0
WLSH1_k127_5021592_0 short chain dehydrogenase - - - 1.284e-218 689.0
WLSH1_k127_5021592_1 Major facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 501.0
WLSH1_k127_5021592_2 Belongs to the DEAD box helicase family K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 479.0
WLSH1_k127_5021592_3 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 373.0
WLSH1_k127_5021592_4 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 354.0
WLSH1_k127_5021592_5 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 300.0
WLSH1_k127_5021592_6 chorismate binding enzyme K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 302.0
WLSH1_k127_5021592_7 cobalt ion transport K02009 - - 0.000000000000000000000000000000003827 132.0
WLSH1_k127_5021592_8 Tetratrico peptide repeat - - - 0.000000000000004971 89.0
WLSH1_k127_5021592_9 domain, Protein K13735,K20276 - - 0.00001991 58.0
WLSH1_k127_5050709_0 RNA binding S1 domain protein K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 381.0
WLSH1_k127_5050709_1 Secretin and TonB N terminus short domain K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.0000000000000000000000000000000000000003813 168.0
WLSH1_k127_5050709_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000006207 95.0
WLSH1_k127_5050709_3 Radical SAM-linked protein - - - 0.00000000000000000007464 92.0
WLSH1_k127_5050709_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0001812 44.0
WLSH1_k127_5150708_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1338.0
WLSH1_k127_5150708_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 620.0
WLSH1_k127_5150708_10 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000006824 171.0
WLSH1_k127_5150708_11 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000000000000000002746 142.0
WLSH1_k127_5150708_12 Smr domain - - - 0.0000000000000000000000000000004236 124.0
WLSH1_k127_5150708_13 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000006124 128.0
WLSH1_k127_5150708_14 Cold shock K03704 - - 0.00000000000000000000000004648 108.0
WLSH1_k127_5150708_15 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000003369 91.0
WLSH1_k127_5150708_16 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000001426 81.0
WLSH1_k127_5150708_17 Cold shock K03704 - - 0.00000000000003794 74.0
WLSH1_k127_5150708_18 zinc-ribbon domain - - - 0.000000007211 60.0
WLSH1_k127_5150708_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 456.0
WLSH1_k127_5150708_20 Uncharacterized ACR, COG1399 K07040 GO:0008150,GO:0040007 - 0.0000002308 58.0
WLSH1_k127_5150708_21 - - - - 0.00008068 48.0
WLSH1_k127_5150708_22 - - - - 0.0002224 46.0
WLSH1_k127_5150708_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 394.0
WLSH1_k127_5150708_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 346.0
WLSH1_k127_5150708_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 334.0
WLSH1_k127_5150708_6 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 308.0
WLSH1_k127_5150708_7 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000158 275.0
WLSH1_k127_5150708_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000006442 227.0
WLSH1_k127_5150708_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000002688 195.0
WLSH1_k127_5240729_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 3.241e-290 919.0
WLSH1_k127_5240729_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.505e-232 739.0
WLSH1_k127_5240729_10 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 450.0
WLSH1_k127_5240729_11 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 452.0
WLSH1_k127_5240729_12 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 427.0
WLSH1_k127_5240729_13 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 426.0
WLSH1_k127_5240729_14 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 389.0
WLSH1_k127_5240729_15 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 383.0
WLSH1_k127_5240729_16 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 362.0
WLSH1_k127_5240729_17 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 363.0
WLSH1_k127_5240729_18 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 361.0
WLSH1_k127_5240729_19 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 346.0
WLSH1_k127_5240729_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 8.109e-221 712.0
WLSH1_k127_5240729_20 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 329.0
WLSH1_k127_5240729_21 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 329.0
WLSH1_k127_5240729_22 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 327.0
WLSH1_k127_5240729_23 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 294.0
WLSH1_k127_5240729_24 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001155 278.0
WLSH1_k127_5240729_25 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009133 269.0
WLSH1_k127_5240729_26 tryptophan synthase activity K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000004867 249.0
WLSH1_k127_5240729_27 CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000008312 246.0
WLSH1_k127_5240729_28 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000007179 228.0
WLSH1_k127_5240729_29 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000001956 209.0
WLSH1_k127_5240729_3 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 5.241e-218 704.0
WLSH1_k127_5240729_30 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000004021 190.0
WLSH1_k127_5240729_31 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000116 186.0
WLSH1_k127_5240729_32 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000001281 181.0
WLSH1_k127_5240729_33 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000002074 181.0
WLSH1_k127_5240729_34 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000003701 170.0
WLSH1_k127_5240729_35 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000004261 145.0
WLSH1_k127_5240729_36 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000349 136.0
WLSH1_k127_5240729_37 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000008739 127.0
WLSH1_k127_5240729_38 - - - - 0.000000000000000000000000000009848 126.0
WLSH1_k127_5240729_39 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000003715 119.0
WLSH1_k127_5240729_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 8.548e-198 623.0
WLSH1_k127_5240729_40 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000006571 117.0
WLSH1_k127_5240729_41 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000001069 115.0
WLSH1_k127_5240729_42 PFAM Class I peptide chain release factor - - - 0.000000000000000000000000001044 117.0
WLSH1_k127_5240729_43 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000005928 105.0
WLSH1_k127_5240729_44 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000003708 96.0
WLSH1_k127_5240729_45 ribosomal small subunit biogenesis K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000001532 98.0
WLSH1_k127_5240729_46 Formiminotransferase-cyclodeaminase - - - 0.00000000000000001913 89.0
WLSH1_k127_5240729_48 Ankyrin repeat - - - 0.000000001789 66.0
WLSH1_k127_5240729_49 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000007153 61.0
WLSH1_k127_5240729_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 632.0
WLSH1_k127_5240729_50 zinc-ribbon domain - - - 0.00001155 52.0
WLSH1_k127_5240729_51 Tetratricopeptide repeat - - - 0.00001302 55.0
WLSH1_k127_5240729_52 Domain of Unknown Function (DUF748) - - - 0.0006984 51.0
WLSH1_k127_5240729_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 529.0
WLSH1_k127_5240729_7 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 482.0
WLSH1_k127_5240729_8 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 454.0
WLSH1_k127_5240729_9 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 460.0
WLSH1_k127_5367190_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 358.0
WLSH1_k127_5367190_1 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 295.0
WLSH1_k127_5367190_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000002789 88.0
WLSH1_k127_544011_0 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 295.0
WLSH1_k127_549468_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 547.0
WLSH1_k127_549468_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 419.0
WLSH1_k127_549468_10 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000001243 225.0
WLSH1_k127_549468_11 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000002117 220.0
WLSH1_k127_549468_12 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000008644 228.0
WLSH1_k127_549468_13 HMGL-like K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000001252 196.0
WLSH1_k127_549468_14 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000001154 209.0
WLSH1_k127_549468_15 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000003248 192.0
WLSH1_k127_549468_16 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000007698 168.0
WLSH1_k127_549468_17 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.00000000000000000000000000000000000000000001617 184.0
WLSH1_k127_549468_18 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000004625 171.0
WLSH1_k127_549468_19 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000004296 147.0
WLSH1_k127_549468_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 349.0
WLSH1_k127_549468_20 heptosyltransferase ii K02843 - - 0.000000000000000000000000000007985 137.0
WLSH1_k127_549468_21 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000002477 115.0
WLSH1_k127_549468_22 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000003775 115.0
WLSH1_k127_549468_23 Nucleoside-diphosphate-sugar epimerase K07276 - - 0.0000000000000000001262 104.0
WLSH1_k127_549468_24 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000005696 97.0
WLSH1_k127_549468_25 Ser Thr phosphatase family protein K01081,K11751 - 3.1.3.5,3.6.1.45 0.0000000000000004546 92.0
WLSH1_k127_549468_26 membrane - - - 0.00000006609 57.0
WLSH1_k127_549468_27 - - - - 0.0000006137 57.0
WLSH1_k127_549468_28 COGs COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) K06378 - - 0.00003701 54.0
WLSH1_k127_549468_29 OstA-like protein K09774 - - 0.0001251 53.0
WLSH1_k127_549468_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 339.0
WLSH1_k127_549468_4 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 322.0
WLSH1_k127_549468_5 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 306.0
WLSH1_k127_549468_6 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 311.0
WLSH1_k127_549468_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 297.0
WLSH1_k127_549468_8 Bifunctional protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001228 271.0
WLSH1_k127_549468_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000003335 251.0
WLSH1_k127_5524404_0 DNA topoisomerase II activity K02469 - 5.99.1.3 3.314e-270 847.0
WLSH1_k127_5524404_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.132e-269 853.0
WLSH1_k127_5524404_10 Belongs to the ParB family K03497 GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002962 262.0
WLSH1_k127_5524404_11 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000006279 235.0
WLSH1_k127_5524404_12 domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000003656 209.0
WLSH1_k127_5524404_13 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000002479 187.0
WLSH1_k127_5524404_14 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000002064 184.0
WLSH1_k127_5524404_15 tigr00255 - - - 0.00000000000000000000000000000000000000000001124 172.0
WLSH1_k127_5524404_16 PFAM TrkA-N domain protein K03499 - - 0.00000000000000000000000000000000000000000003352 168.0
WLSH1_k127_5524404_17 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000002227 143.0
WLSH1_k127_5524404_18 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000001048 136.0
WLSH1_k127_5524404_19 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000343 119.0
WLSH1_k127_5524404_2 threonyl-tRNA aminoacylation K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.659e-199 636.0
WLSH1_k127_5524404_20 - - - - 0.000000000000000000000000004412 116.0
WLSH1_k127_5524404_21 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000371 83.0
WLSH1_k127_5524404_22 R3H domain protein K06346 - - 0.000000004149 59.0
WLSH1_k127_5524404_23 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000003902 57.0
WLSH1_k127_5524404_24 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000005025 55.0
WLSH1_k127_5524404_25 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00001003 50.0
WLSH1_k127_5524404_3 Cation transport protein K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 512.0
WLSH1_k127_5524404_4 ATPase, AAA family K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 476.0
WLSH1_k127_5524404_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 437.0
WLSH1_k127_5524404_6 phenylalanyl-tRNA synthetase (beta subunit) K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 435.0
WLSH1_k127_5524404_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 397.0
WLSH1_k127_5524404_8 COG1192 ATPases involved in chromosome partitioning K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 322.0
WLSH1_k127_5524404_9 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 311.0
WLSH1_k127_5615079_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 513.0
WLSH1_k127_5615079_1 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 407.0
WLSH1_k127_5615079_10 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000182 97.0
WLSH1_k127_5615079_11 lipolytic protein G-D-S-L family - - - 0.000000000002803 71.0
WLSH1_k127_5615079_12 - - - - 0.000007525 49.0
WLSH1_k127_5615079_2 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 336.0
WLSH1_k127_5615079_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 343.0
WLSH1_k127_5615079_4 Electron transport complex K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001193 273.0
WLSH1_k127_5615079_5 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000001298 229.0
WLSH1_k127_5615079_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000003137 196.0
WLSH1_k127_5615079_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000003112 201.0
WLSH1_k127_5615079_8 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000001456 169.0
WLSH1_k127_5615079_9 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000007601 102.0
WLSH1_k127_5696897_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.733e-299 945.0
WLSH1_k127_5696897_1 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 494.0
WLSH1_k127_5696897_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 325.0
WLSH1_k127_5696897_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001568 283.0
WLSH1_k127_5696897_12 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001688 281.0
WLSH1_k127_5696897_13 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000006685 264.0
WLSH1_k127_5696897_14 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000002381 216.0
WLSH1_k127_5696897_15 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000004792 215.0
WLSH1_k127_5696897_16 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000007395 199.0
WLSH1_k127_5696897_17 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000001108 166.0
WLSH1_k127_5696897_18 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000005155 166.0
WLSH1_k127_5696897_19 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000005085 147.0
WLSH1_k127_5696897_2 Penicillin-binding Protein dimerisation domain K03587,K08384,K08724,K12552,K12556 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 437.0
WLSH1_k127_5696897_20 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000402 139.0
WLSH1_k127_5696897_21 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000003933 146.0
WLSH1_k127_5696897_22 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000196 110.0
WLSH1_k127_5696897_23 Peptidase MA superfamily - - - 0.00000000001272 75.0
WLSH1_k127_5696897_24 Cell division protein FtsQ K03589 - - 0.0000002473 61.0
WLSH1_k127_5696897_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 430.0
WLSH1_k127_5696897_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 419.0
WLSH1_k127_5696897_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 402.0
WLSH1_k127_5696897_6 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 355.0
WLSH1_k127_5696897_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 347.0
WLSH1_k127_5696897_8 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 348.0
WLSH1_k127_5696897_9 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 336.0
WLSH1_k127_5754054_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 402.0
WLSH1_k127_5764513_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 442.0
WLSH1_k127_5764513_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 292.0
WLSH1_k127_5764513_2 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000008854 225.0
WLSH1_k127_5764513_3 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000001931 213.0
WLSH1_k127_5764513_4 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000007136 123.0
WLSH1_k127_5764513_5 - - - - 0.00000002423 58.0
WLSH1_k127_5801253_0 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 1.627e-223 715.0
WLSH1_k127_5801253_1 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 567.0
WLSH1_k127_5801253_10 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000000000000000000000000000002327 194.0
WLSH1_k127_5801253_11 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000001013 165.0
WLSH1_k127_5801253_12 dehydrogenase domain of multifunctional non-ribosomal peptide - - - 0.00000000000000000000000000000009054 138.0
WLSH1_k127_5801253_13 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000005454 113.0
WLSH1_k127_5801253_14 Protein of unknown function DUF58 - - - 0.000000000000000000000003287 116.0
WLSH1_k127_5801253_15 Proteolipid membrane potential modulator - - - 0.0000000000007459 69.0
WLSH1_k127_5801253_16 peptidoglycan-binding domain-containing protein - - - 0.000000002602 65.0
WLSH1_k127_5801253_17 Peptidoglycan-binding domain 1 protein - - - 0.000000003617 63.0
WLSH1_k127_5801253_18 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.000001445 51.0
WLSH1_k127_5801253_2 COG0714 MoxR-like ATPases K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 342.0
WLSH1_k127_5801253_3 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 313.0
WLSH1_k127_5801253_4 PFAM Uracil-DNA glycosylase superfamily K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000079 257.0
WLSH1_k127_5801253_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001187 251.0
WLSH1_k127_5801253_6 PFAM 4Fe-4S ferredoxin, iron-sulphur binding, subgroup - - - 0.00000000000000000000000000000000000000000000000000000000002824 215.0
WLSH1_k127_5801253_7 Serine aminopeptidase, S33 K18100 - - 0.0000000000000000000000000000000000000000000000000000000001042 214.0
WLSH1_k127_5801253_8 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000008392 201.0
WLSH1_k127_5801253_9 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K00697,K01087,K16055 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000000000000000009328 203.0
WLSH1_k127_5845626_0 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 319.0
WLSH1_k127_5845626_1 Pyruvate kinase K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 312.0
WLSH1_k127_5845626_2 Ferritin-like domain K02217 - 1.16.3.2 0.000002832 49.0
WLSH1_k127_5925872_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 483.0
WLSH1_k127_5925872_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 452.0
WLSH1_k127_5925872_10 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000000003008 186.0
WLSH1_k127_5925872_11 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000001214 180.0
WLSH1_k127_5925872_12 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00001155 48.0
WLSH1_k127_5925872_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 344.0
WLSH1_k127_5925872_3 Stage 0 sporulation protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002089 279.0
WLSH1_k127_5925872_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004392 277.0
WLSH1_k127_5925872_5 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001487 273.0
WLSH1_k127_5925872_6 Bacterial transferase hexapeptide (six repeats) K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000002247 265.0
WLSH1_k127_5925872_7 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000001089 235.0
WLSH1_k127_5925872_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000005546 194.0
WLSH1_k127_5925872_9 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000001127 192.0
WLSH1_k127_5980984_0 NAD- dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 413.0
WLSH1_k127_5980984_1 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 305.0
WLSH1_k127_5980984_2 UDP binding domain K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000003726 249.0
WLSH1_k127_5980984_3 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000006134 96.0
WLSH1_k127_5986174_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 481.0
WLSH1_k127_5986174_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 300.0
WLSH1_k127_5986174_2 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000002332 235.0
WLSH1_k127_5986174_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000747 183.0
WLSH1_k127_5986174_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000001771 170.0
WLSH1_k127_6013603_0 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000004042 156.0
WLSH1_k127_6013603_1 Secretin and TonB N terminus short domain K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.00000000000000000000000000104 128.0
WLSH1_k127_6158535_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 2.289e-212 667.0
WLSH1_k127_6158535_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000001191 204.0
WLSH1_k127_6158535_2 Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000775 166.0
WLSH1_k127_6158535_3 PFAM Rubredoxin-type Fe(Cys)4 protein K05297 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592 1.18.1.1 0.0000000000000000000000002053 106.0
WLSH1_k127_6158535_4 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000002226 87.0
WLSH1_k127_6158535_5 - - - - 0.00000000000000006049 82.0
WLSH1_k127_6159072_0 RmlD substrate binding domain K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 347.0
WLSH1_k127_6159072_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000001988 164.0
WLSH1_k127_6159072_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000001726 148.0
WLSH1_k127_6159072_3 radical SAM domain protein K15045 - - 0.00001942 56.0
WLSH1_k127_6180493_0 PFAM glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001228 264.0
WLSH1_k127_6180493_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000005194 240.0
WLSH1_k127_6180493_2 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000001546 177.0
WLSH1_k127_6187010_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 344.0
WLSH1_k127_6187010_1 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000001231 161.0
WLSH1_k127_6187010_2 PHP domain K07053 - 3.1.3.97 0.00000000000000000000000002715 111.0
WLSH1_k127_6257418_0 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006698 248.0
WLSH1_k127_6257418_1 Type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000851 223.0
WLSH1_k127_6257418_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000001744 211.0
WLSH1_k127_6343935_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1664.0
WLSH1_k127_6343935_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1229.0
WLSH1_k127_6343935_10 DegT/DnrJ/EryC1/StrS aminotransferase family K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 441.0
WLSH1_k127_6343935_11 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 397.0
WLSH1_k127_6343935_12 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 373.0
WLSH1_k127_6343935_13 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 364.0
WLSH1_k127_6343935_14 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 352.0
WLSH1_k127_6343935_15 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 302.0
WLSH1_k127_6343935_16 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000005397 255.0
WLSH1_k127_6343935_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001559 252.0
WLSH1_k127_6343935_18 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000232 254.0
WLSH1_k127_6343935_19 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000001555 249.0
WLSH1_k127_6343935_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 9.042e-288 900.0
WLSH1_k127_6343935_20 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000001711 248.0
WLSH1_k127_6343935_21 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000004265 231.0
WLSH1_k127_6343935_22 Belongs to the PdxA family K22024 - 1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000108 236.0
WLSH1_k127_6343935_23 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000001461 223.0
WLSH1_k127_6343935_24 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000002653 213.0
WLSH1_k127_6343935_25 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000062 203.0
WLSH1_k127_6343935_26 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000002536 209.0
WLSH1_k127_6343935_27 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000004272 203.0
WLSH1_k127_6343935_28 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000005565 203.0
WLSH1_k127_6343935_29 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000002763 203.0
WLSH1_k127_6343935_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.941e-242 775.0
WLSH1_k127_6343935_30 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000005082 193.0
WLSH1_k127_6343935_31 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000002344 188.0
WLSH1_k127_6343935_32 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000002911 186.0
WLSH1_k127_6343935_33 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000005709 188.0
WLSH1_k127_6343935_34 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000001033 184.0
WLSH1_k127_6343935_35 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000007491 180.0
WLSH1_k127_6343935_36 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000001199 181.0
WLSH1_k127_6343935_37 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000004699 164.0
WLSH1_k127_6343935_38 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000003311 159.0
WLSH1_k127_6343935_39 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000001009 160.0
WLSH1_k127_6343935_4 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.59e-197 634.0
WLSH1_k127_6343935_40 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000004625 153.0
WLSH1_k127_6343935_41 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000009987 148.0
WLSH1_k127_6343935_42 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000006387 142.0
WLSH1_k127_6343935_43 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000931 140.0
WLSH1_k127_6343935_44 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000003709 140.0
WLSH1_k127_6343935_45 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000001549 126.0
WLSH1_k127_6343935_46 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000002058 129.0
WLSH1_k127_6343935_47 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000003093 119.0
WLSH1_k127_6343935_48 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000007941 101.0
WLSH1_k127_6343935_49 mitochondrial genome maintenance K02879,K16193 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000009092 108.0
WLSH1_k127_6343935_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 604.0
WLSH1_k127_6343935_50 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002545 95.0
WLSH1_k127_6343935_51 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000003485 93.0
WLSH1_k127_6343935_52 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000006593 89.0
WLSH1_k127_6343935_53 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000005258 87.0
WLSH1_k127_6343935_54 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00000000000000002845 93.0
WLSH1_k127_6343935_55 Modulates RecA activity K03565,K19002 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 0.000000000000000247 85.0
WLSH1_k127_6343935_56 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000004251 85.0
WLSH1_k127_6343935_57 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000001666 79.0
WLSH1_k127_6343935_58 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000005225 76.0
WLSH1_k127_6343935_59 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000004609 66.0
WLSH1_k127_6343935_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 568.0
WLSH1_k127_6343935_60 Peptidoglycan-binding domain 1 protein K07273 - - 0.0000001463 59.0
WLSH1_k127_6343935_61 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000002326 55.0
WLSH1_k127_6343935_62 structural constituent of ribosome K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000004958 55.0
WLSH1_k127_6343935_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 518.0
WLSH1_k127_6343935_8 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 514.0
WLSH1_k127_6343935_9 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 464.0
WLSH1_k127_6476968_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 458.0
WLSH1_k127_6476968_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000975 226.0
WLSH1_k127_6476968_2 PAS domain - - - 0.0000000000000000000000008695 107.0
WLSH1_k127_6476968_3 response regulator, receiver K02030,K13040 - 2.7.13.3 0.00000000000001016 85.0
WLSH1_k127_6476968_4 PFAM VanZ family protein - - - 0.000000000004355 72.0
WLSH1_k127_6480516_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 452.0
WLSH1_k127_6480516_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 396.0
WLSH1_k127_6480516_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000032 284.0
WLSH1_k127_6480516_3 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0000000000000000000000006451 109.0
WLSH1_k127_6480516_4 AMP-binding enzyme C-terminal domain - - - 0.00000000000104 70.0
WLSH1_k127_6552392_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.283e-239 755.0
WLSH1_k127_6552392_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000001502 254.0
WLSH1_k127_6552392_2 PBS lyase HEAT-like repeat - - - 0.0000000004907 72.0
WLSH1_k127_6552392_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000007515 61.0
WLSH1_k127_6600501_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 456.0
WLSH1_k127_6600501_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 444.0
WLSH1_k127_6600501_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 391.0
WLSH1_k127_6600501_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009964 274.0
WLSH1_k127_6600501_4 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000001068 128.0
WLSH1_k127_6600501_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000001037 66.0
WLSH1_k127_6600501_6 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.000001533 53.0
WLSH1_k127_6600501_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00001492 55.0
WLSH1_k127_6600501_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00003837 49.0
WLSH1_k127_660262_0 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 449.0
WLSH1_k127_660262_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K03387 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 288.0
WLSH1_k127_660262_2 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001396 247.0
WLSH1_k127_660262_3 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000007252 200.0
WLSH1_k127_660262_4 NifU-like domain - - - 0.0000000000000000000000000003659 114.0
WLSH1_k127_660262_5 glutaredoxin-like protein, YruB-family - - - 0.00000000000000000000007935 99.0
WLSH1_k127_660262_6 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000006408 94.0
WLSH1_k127_660262_7 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000006251 57.0
WLSH1_k127_6614938_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 301.0
WLSH1_k127_6614938_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000007469 204.0
WLSH1_k127_6638276_0 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000001417 253.0
WLSH1_k127_6638276_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000006539 210.0
WLSH1_k127_6688424_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 529.0
WLSH1_k127_6688424_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 362.0
WLSH1_k127_6688424_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000009176 82.0
WLSH1_k127_6688424_11 Lysin motif - - - 0.000000006079 64.0
WLSH1_k127_6688424_2 Phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 336.0
WLSH1_k127_6688424_3 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 317.0
WLSH1_k127_6688424_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000004319 268.0
WLSH1_k127_6688424_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000005549 192.0
WLSH1_k127_6688424_6 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000005115 151.0
WLSH1_k127_6688424_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000001193 136.0
WLSH1_k127_6688424_8 PQQ-like domain - - - 0.00000000000000000000000000001094 119.0
WLSH1_k127_6688424_9 Belongs to the bacterial histone-like protein family K03530,K05788 - - 0.000000000000000000001341 97.0
WLSH1_k127_6825920_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 1.663e-253 794.0
WLSH1_k127_6825920_1 Glutamine synthetase type III K01915 - 6.3.1.2 1.222e-228 729.0
WLSH1_k127_6825920_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 345.0
WLSH1_k127_6825920_11 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001751 265.0
WLSH1_k127_6825920_12 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000002987 220.0
WLSH1_k127_6825920_13 Thioredoxin-like [2Fe-2S] ferredoxin - - - 0.000000000000000000000000000000000000000000000000000652 188.0
WLSH1_k127_6825920_14 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000005326 164.0
WLSH1_k127_6825920_15 Ferredoxin K00335,K17992 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000105 153.0
WLSH1_k127_6825920_16 cheY-homologous receiver domain K07658 - - 0.0000000000000000000000000000002556 126.0
WLSH1_k127_6825920_17 bacteriocin transport K03561,K03562 - - 0.0000000000000000000000001735 113.0
WLSH1_k127_6825920_18 Iron-only hydrogenase system regulator - - - 0.000000000000000000000001437 105.0
WLSH1_k127_6825920_19 Hydrogenase maturation protease K08315 - 3.4.23.51 0.0000000000000000001025 96.0
WLSH1_k127_6825920_2 Nickel-dependent hydrogenase - - - 1.74e-206 649.0
WLSH1_k127_6825920_20 Biopolymer transport protein K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000004695 74.0
WLSH1_k127_6825920_21 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000002819 55.0
WLSH1_k127_6825920_3 iron-sulfur cluster assembly K00336,K18332 - 1.12.1.3,1.6.5.3 5.086e-204 650.0
WLSH1_k127_6825920_4 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 469.0
WLSH1_k127_6825920_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 457.0
WLSH1_k127_6825920_6 biotin synthase activity K01012,K04653 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009067 419.0
WLSH1_k127_6825920_7 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 393.0
WLSH1_k127_6825920_8 ammonium transporteR K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 384.0
WLSH1_k127_6825920_9 coenzyme F420 hydrogenase activity K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 361.0
WLSH1_k127_6839648_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1187.0
WLSH1_k127_6839648_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.57e-246 770.0
WLSH1_k127_6839648_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 7.288e-208 658.0
WLSH1_k127_6839648_3 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 533.0
WLSH1_k127_6839648_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000008711 178.0
WLSH1_k127_6839648_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000004175 127.0
WLSH1_k127_6839648_6 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0009165 42.0
WLSH1_k127_6872060_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004465 269.0
WLSH1_k127_6872060_1 ORF6N domain - - - 0.000000000000000000000000000000000000000008363 159.0
WLSH1_k127_6872060_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000004729 150.0
WLSH1_k127_6930552_0 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 506.0
WLSH1_k127_6930552_1 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002151 253.0
WLSH1_k127_7043177_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 305.0
WLSH1_k127_7043177_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 306.0
WLSH1_k127_7043177_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000008057 147.0
WLSH1_k127_7114086_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 581.0
WLSH1_k127_7114086_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 556.0
WLSH1_k127_7114086_10 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 324.0
WLSH1_k127_7114086_11 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 327.0
WLSH1_k127_7114086_12 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 317.0
WLSH1_k127_7114086_13 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 288.0
WLSH1_k127_7114086_14 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000003542 251.0
WLSH1_k127_7114086_15 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000008018 231.0
WLSH1_k127_7114086_16 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000001418 226.0
WLSH1_k127_7114086_17 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704,K20453 - 4.2.1.33,4.2.1.35,4.2.1.85 0.0000000000000000000000000000000000000000000000000000002957 198.0
WLSH1_k127_7114086_18 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000007244 189.0
WLSH1_k127_7114086_19 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000001149 145.0
WLSH1_k127_7114086_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 520.0
WLSH1_k127_7114086_20 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000002356 127.0
WLSH1_k127_7114086_21 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000002039 115.0
WLSH1_k127_7114086_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 473.0
WLSH1_k127_7114086_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 458.0
WLSH1_k127_7114086_5 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 449.0
WLSH1_k127_7114086_6 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 407.0
WLSH1_k127_7114086_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 357.0
WLSH1_k127_7114086_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 336.0
WLSH1_k127_7114086_9 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 333.0
WLSH1_k127_7143803_0 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 386.0
WLSH1_k127_7143803_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 347.0
WLSH1_k127_7143803_10 Hydrolase, P-loop family K06925 - - 0.00000000000000000000000000000007278 130.0
WLSH1_k127_7143803_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000008631 211.0
WLSH1_k127_7143803_3 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000002803 182.0
WLSH1_k127_7143803_4 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000002971 166.0
WLSH1_k127_7143803_5 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000006448 154.0
WLSH1_k127_7143803_6 Glycoprotease K14742 - - 0.00000000000000000000000000000000001989 145.0
WLSH1_k127_7143803_7 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000002587 148.0
WLSH1_k127_7143803_8 Maf-like protein K06287 - - 0.0000000000000000000000000000000002149 147.0
WLSH1_k127_7143803_9 Peptidase family M48 - - - 0.0000000000000000000000000000000002909 146.0
WLSH1_k127_7185689_0 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 443.0
WLSH1_k127_7185689_1 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 322.0
WLSH1_k127_7185689_10 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000001647 56.0
WLSH1_k127_7185689_11 - - - - 0.000131 49.0
WLSH1_k127_7185689_12 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0003371 47.0
WLSH1_k127_7185689_13 Stage II sporulation protein P (SpoIIP) K06385 - - 0.0005072 51.0
WLSH1_k127_7185689_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 309.0
WLSH1_k127_7185689_3 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 297.0
WLSH1_k127_7185689_4 HD domain - - - 0.000000000000000000000000000000000000000000000000004353 194.0
WLSH1_k127_7185689_5 HIT domain K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000006007 184.0
WLSH1_k127_7185689_6 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000002967 177.0
WLSH1_k127_7185689_7 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000001708 158.0
WLSH1_k127_7185689_8 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.000000000000000000000000000000286 130.0
WLSH1_k127_7270311_0 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.00000000000000000000000000000000000000000000000000004544 208.0
WLSH1_k127_7270311_1 Domain of unknown function DUF11 - - - 0.00000182 59.0
WLSH1_k127_7288699_0 PFAM Carbamoyl-phosphate synthase L chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 1.624e-234 736.0
WLSH1_k127_7288699_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 2.538e-222 695.0
WLSH1_k127_7288699_10 metalloendopeptidase activity K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000001292 247.0
WLSH1_k127_7288699_12 Oxidoreductase domain protein - - - 0.00004046 47.0
WLSH1_k127_7288699_2 Domain of unknown function (DUF1846) - - - 8.637e-217 685.0
WLSH1_k127_7288699_3 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 474.0
WLSH1_k127_7288699_4 Pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 470.0
WLSH1_k127_7288699_5 maturation GTPase HydF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 444.0
WLSH1_k127_7288699_6 PFAM beta-lactamase domain protein K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 423.0
WLSH1_k127_7288699_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 407.0
WLSH1_k127_7288699_8 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 306.0
WLSH1_k127_7288699_9 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 300.0
WLSH1_k127_7302415_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 508.0
WLSH1_k127_7302415_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 434.0
WLSH1_k127_7302415_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 400.0
WLSH1_k127_7302415_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005153 279.0
WLSH1_k127_7302415_4 NAD dependent epimerase dehydratase - - - 0.0000000000000000000000000000000001347 143.0
WLSH1_k127_7302415_5 PQ loop repeat K15383 - - 0.00000000000000206 79.0
WLSH1_k127_7302415_6 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0001147 45.0
WLSH1_k127_7330054_0 PFAM MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 377.0
WLSH1_k127_7330054_1 Receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003372 292.0
WLSH1_k127_7330054_2 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001215 276.0
WLSH1_k127_7354589_0 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 454.0
WLSH1_k127_7354589_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 357.0
WLSH1_k127_7354589_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000009555 133.0
WLSH1_k127_7354589_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0001298 51.0
WLSH1_k127_7354589_2 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 347.0
WLSH1_k127_7354589_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 319.0
WLSH1_k127_7354589_4 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000227 279.0
WLSH1_k127_7354589_5 Psort location CytoplasmicMembrane, score 10.00 K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007309 275.0
WLSH1_k127_7354589_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000008148 255.0
WLSH1_k127_7354589_7 ANTAR - - - 0.000000000000000000000000000000000000000000000000000000004091 207.0
WLSH1_k127_7354589_8 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000006356 207.0
WLSH1_k127_7354589_9 Transcriptional regulator, AsnC family - - - 0.00000000000000000000000000000000000000000002768 167.0
WLSH1_k127_7364082_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 1.176e-213 671.0
WLSH1_k127_7364082_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 576.0
WLSH1_k127_7364082_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000001046 187.0
WLSH1_k127_7364082_11 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000005496 175.0
WLSH1_k127_7364082_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000005881 166.0
WLSH1_k127_7364082_14 PFAM Ribose galactose isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000001082 161.0
WLSH1_k127_7364082_15 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000003869 155.0
WLSH1_k127_7364082_16 Cupin domain protein - - - 0.000000000000000000000000000000000006065 139.0
WLSH1_k127_7364082_17 Bifunctional nuclease K08999 - - 0.000000000000000000000000000002555 124.0
WLSH1_k127_7364082_18 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000002182 105.0
WLSH1_k127_7364082_19 PFAM AsmA family K07289 - - 0.000000000001433 81.0
WLSH1_k127_7364082_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 504.0
WLSH1_k127_7364082_20 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000004486 61.0
WLSH1_k127_7364082_3 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 438.0
WLSH1_k127_7364082_4 SPFH Band 7 PHB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003608 267.0
WLSH1_k127_7364082_5 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000001328 271.0
WLSH1_k127_7364082_6 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000001717 224.0
WLSH1_k127_7364082_7 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000002928 220.0
WLSH1_k127_7364082_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000009201 198.0
WLSH1_k127_7364082_9 MORN repeat variant - - - 0.00000000000000000000000000000000000000000000000001938 193.0
WLSH1_k127_7369594_0 CobQ/CobB/MinD/ParA nucleotide binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 344.0
WLSH1_k127_7369594_1 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 338.0
WLSH1_k127_7369594_2 PFAM zinc iron permease K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005215 244.0
WLSH1_k127_7369594_3 Metal-dependent hydrolase of the beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000003385 172.0
WLSH1_k127_7369594_4 DsrE/DsrF-like family K06039 - - 0.00000000000000000000000000000000000004428 145.0
WLSH1_k127_7369594_5 Nitrogen-fixing NifU domain protein K04488 - - 0.000000000000000000002404 98.0
WLSH1_k127_7369594_6 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000008817 81.0
WLSH1_k127_7369594_7 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000002512 63.0
WLSH1_k127_7451169_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 404.0
WLSH1_k127_7451169_1 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 343.0
WLSH1_k127_7451169_2 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 301.0
WLSH1_k127_7451169_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
WLSH1_k127_7451169_4 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000008957 259.0
WLSH1_k127_7451169_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000006489 250.0
WLSH1_k127_7451169_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.00000000000000000000000000000000000000000000000000003532 196.0
WLSH1_k127_7451169_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000001284 95.0
WLSH1_k127_7451169_9 hydrolase K01048 - 3.1.1.5 0.00005518 49.0
WLSH1_k127_7490693_0 PFAM HhH-GPD family protein K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000003962 237.0
WLSH1_k127_7490693_1 regulation of single-species biofilm formation K02342,K03763,K13573 - 2.7.7.7 0.00000000000000000000000000000003255 136.0
WLSH1_k127_7490693_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000542 134.0
WLSH1_k127_7490693_3 domain, Protein - - - 0.0000000000000000002105 103.0
WLSH1_k127_7496246_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 7.833e-300 938.0
WLSH1_k127_7496246_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 379.0
WLSH1_k127_7496246_2 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000007487 249.0
WLSH1_k127_7496246_3 ROK family - - - 0.000000000000000000000000000000000000000000000000000003124 206.0
WLSH1_k127_7496246_4 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000001125 196.0
WLSH1_k127_7496246_5 nuclear chromosome segregation - - - 0.0004773 52.0
WLSH1_k127_7518233_0 L-glutamate biosynthetic process K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1727.0
WLSH1_k127_7518233_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 1.5e-323 1011.0
WLSH1_k127_7518233_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.604e-212 671.0
WLSH1_k127_7518233_3 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 549.0
WLSH1_k127_7518233_4 TIGRFAM amino acid adenylation domain - - - 0.000000000000000000000000000000000000000000000001413 192.0
WLSH1_k127_7518233_5 Domain of unknown function (DUF1736) - - - 0.000000000000000000000000000000000002265 156.0
WLSH1_k127_7518233_6 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.0000000004727 63.0
WLSH1_k127_7698389_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 340.0
WLSH1_k127_7698389_1 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000008775 196.0
WLSH1_k127_7698389_2 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000005954 159.0
WLSH1_k127_7887514_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000001854 210.0
WLSH1_k127_7887514_1 B12 binding domain - - - 0.000000000002097 72.0
WLSH1_k127_7921562_0 Na Pi-cotransporter II-like protein K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 488.0
WLSH1_k127_7921562_1 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 423.0
WLSH1_k127_7921562_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 361.0
WLSH1_k127_7921562_3 Two component transcriptional regulator, winged helix family K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003507 267.0
WLSH1_k127_7921562_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007341 266.0
WLSH1_k127_7921562_5 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000004222 106.0
WLSH1_k127_799883_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000006901 199.0
WLSH1_k127_799883_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000015 147.0
WLSH1_k127_799883_2 transmembrane transporter activity K03296 - - 0.000000000000000000000000000002231 124.0
WLSH1_k127_799883_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000003038 128.0
WLSH1_k127_799883_4 MacB-like periplasmic core domain - - - 0.000000000000000000007122 96.0
WLSH1_k127_799883_5 PFAM outer membrane efflux protein - - - 0.00000000000000000004389 104.0
WLSH1_k127_799883_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000002565 67.0
WLSH1_k127_799883_7 radical SAM domain protein K07011,K22227 - - 0.0000000005552 71.0
WLSH1_k127_8094439_0 Elongator protein 3, MiaB family, Radical SAM - - - 4.58e-213 668.0
WLSH1_k127_8094439_1 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000008456 151.0
WLSH1_k127_8094439_2 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000002359 134.0
WLSH1_k127_8094439_3 B12 binding domain K04034 - 1.21.98.3 0.0000000000000006051 79.0
WLSH1_k127_8297665_0 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006501 285.0
WLSH1_k127_8297665_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000003944 206.0
WLSH1_k127_8395887_0 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 377.0
WLSH1_k127_8395887_1 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.000000000000000000000000000000000001165 146.0
WLSH1_k127_8395887_2 Predicted permease K07089 - - 0.000000000000000000000000000000000007111 148.0
WLSH1_k127_8464723_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 544.0
WLSH1_k127_8464723_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 516.0
WLSH1_k127_8464723_10 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000605 140.0
WLSH1_k127_8464723_11 Polymer-forming cytoskeletal - - - 0.000000000000008969 81.0
WLSH1_k127_8464723_12 DNA binding domain, excisionase family K07219 - - 0.0007044 46.0
WLSH1_k127_8464723_2 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 435.0
WLSH1_k127_8464723_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 393.0
WLSH1_k127_8464723_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 325.0
WLSH1_k127_8464723_5 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000001106 243.0
WLSH1_k127_8464723_6 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000002724 240.0
WLSH1_k127_8464723_7 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000003737 194.0
WLSH1_k127_8464723_8 PFAM Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000002328 160.0
WLSH1_k127_8464723_9 MgtC SapB transporter K07507 - - 0.00000000000000000000000000000000000004117 147.0
WLSH1_k127_8519420_0 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000736 229.0
WLSH1_k127_8519420_1 PFAM ABC transporter related K09691 - - 0.00000000000000000000000000000000000000000004536 177.0
WLSH1_k127_8538681_0 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 570.0
WLSH1_k127_8538681_1 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000003104 216.0
WLSH1_k127_8538681_2 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000000000000008215 186.0
WLSH1_k127_8538681_3 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000001073 179.0
WLSH1_k127_8538681_4 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.000000000000000000948 88.0
WLSH1_k127_8538681_5 O-Antigen ligase - - - 0.0000000003198 72.0
WLSH1_k127_8571495_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 390.0
WLSH1_k127_8571495_1 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000001741 231.0
WLSH1_k127_8571495_2 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000814 201.0
WLSH1_k127_8571495_3 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000243 173.0
WLSH1_k127_8571495_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000007213 83.0
WLSH1_k127_8571495_5 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.0000000000000711 75.0
WLSH1_k127_8571495_6 thioesterase K07107 - - 0.0005558 48.0
WLSH1_k127_8608161_0 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000699 252.0
WLSH1_k127_8608161_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000003317 222.0
WLSH1_k127_8608161_2 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000102 181.0
WLSH1_k127_8608161_3 COG3291 FOG PKD repeat K01387 GO:0005575,GO:0005576 3.4.24.3 0.0000001944 62.0
WLSH1_k127_8608161_4 Helix-turn-helix XRE-family like proteins - - - 0.0007442 43.0
WLSH1_k127_8778894_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 9.553e-240 752.0
WLSH1_k127_8778894_1 Dehydratase family K01687 - 4.2.1.9 3.441e-230 724.0
WLSH1_k127_8778894_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008179 327.0
WLSH1_k127_8778894_11 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 326.0
WLSH1_k127_8778894_12 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 291.0
WLSH1_k127_8778894_13 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 292.0
WLSH1_k127_8778894_14 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000008423 220.0
WLSH1_k127_8778894_15 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000008002 192.0
WLSH1_k127_8778894_16 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000002274 187.0
WLSH1_k127_8778894_17 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000001043 167.0
WLSH1_k127_8778894_18 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.0000000000000000000000000000000000000001855 154.0
WLSH1_k127_8778894_19 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000001694 90.0
WLSH1_k127_8778894_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 6.127e-196 617.0
WLSH1_k127_8778894_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 580.0
WLSH1_k127_8778894_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 559.0
WLSH1_k127_8778894_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 512.0
WLSH1_k127_8778894_6 ABC transporter K02021,K06147,K06148,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 512.0
WLSH1_k127_8778894_7 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 475.0
WLSH1_k127_8778894_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 446.0
WLSH1_k127_8778894_9 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 408.0
WLSH1_k127_8788128_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001413 256.0
WLSH1_k127_8788128_1 hopanoid biosynthesis associated protein HpnK - - - 0.000000000000000000000000000000000000000000000000000000000000009877 226.0
WLSH1_k127_8788128_10 Methyltransferase small domain - - - 0.0000000000000000002261 96.0
WLSH1_k127_8788128_2 PFAM Glycosyl transferase family 2 K12992 - - 0.0000000000000000000000000000000000000000000000000005342 195.0
WLSH1_k127_8788128_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000003658 183.0
WLSH1_k127_8788128_4 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000000000006776 181.0
WLSH1_k127_8788128_5 methyltransferase - - - 0.0000000000000000000000000000000000000000000000615 178.0
WLSH1_k127_8788128_6 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000002204 164.0
WLSH1_k127_8788128_7 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000001534 156.0
WLSH1_k127_8788128_8 PFAM Glycosyl transferase family 2 K12992 - - 0.000000000000000000000000000000003261 139.0
WLSH1_k127_8788128_9 PFAM Radical SAM domain protein - - - 0.0000000000000000000003856 102.0
WLSH1_k127_9084871_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000006974 206.0
WLSH1_k127_9084871_1 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000004946 185.0
WLSH1_k127_9084871_2 - K07341 - - 0.000000000000000000000006545 106.0
WLSH1_k127_9084871_3 L-fuculose phosphate aldolase K01628 K01628 - 4.1.2.17 0.00000000000000000001688 103.0
WLSH1_k127_9141817_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 296.0
WLSH1_k127_9141817_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 296.0
WLSH1_k127_9141817_2 Predicted permease K07089 - - 0.00000000000000000000000000000002565 133.0
WLSH1_k127_9141817_3 - - - - 0.00000000000000008308 82.0
WLSH1_k127_9141817_4 Transcriptional regulator - - - 0.0000000000000007482 83.0
WLSH1_k127_9222269_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.877e-205 653.0
WLSH1_k127_9222269_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 418.0
WLSH1_k127_9222269_10 Glycosyltransferase 36 associated - - - 0.000000000000000000000000000000000007913 140.0
WLSH1_k127_9222269_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000008808 135.0
WLSH1_k127_9222269_12 RNase H K03469 - 3.1.26.4 0.0000000000000000000000000000001286 128.0
WLSH1_k127_9222269_13 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000001213 123.0
WLSH1_k127_9222269_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.0000000000000000000000000001873 121.0
WLSH1_k127_9222269_15 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.00000000000000000000001815 110.0
WLSH1_k127_9222269_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 369.0
WLSH1_k127_9222269_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 363.0
WLSH1_k127_9222269_4 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 288.0
WLSH1_k127_9222269_5 belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K03977,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25,6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000001736 219.0
WLSH1_k127_9222269_6 Prephenate dehydrogenase K00210,K00220,K04517 - 1.3.1.12,1.3.1.43 0.0000000000000000000000000000000000000000000000000000000000001739 221.0
WLSH1_k127_9222269_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000003584 208.0
WLSH1_k127_9222269_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000002017 174.0
WLSH1_k127_9222269_9 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000002429 160.0
WLSH1_k127_9286984_0 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000005102 209.0
WLSH1_k127_9286984_1 Glycosyl transferases group 1 - - - 0.00000004871 66.0
WLSH1_k127_9375769_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 355.0
WLSH1_k127_9375769_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 336.0
WLSH1_k127_9375769_10 Smr domain - - - 0.00000002188 61.0
WLSH1_k127_9375769_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000009631 246.0
WLSH1_k127_9375769_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000007533 184.0
WLSH1_k127_9375769_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000002243 150.0
WLSH1_k127_9375769_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000114 139.0
WLSH1_k127_9375769_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000008772 102.0
WLSH1_k127_9375769_7 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000002859 85.0
WLSH1_k127_9375769_8 Glycosyltransferase Family 4 - - - 0.000000001399 70.0
WLSH1_k127_9375769_9 COG NOG19114 non supervised orthologous group - - - 0.000000004871 61.0
WLSH1_k127_9407794_0 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 464.0
WLSH1_k127_9407794_1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000001194 218.0
WLSH1_k127_9407794_2 TM2 domain - - - 0.000000003869 62.0
WLSH1_k127_9541230_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 320.0
WLSH1_k127_9541230_1 type II secretion system protein E K02243,K02652 - - 0.00000000000003227 80.0
WLSH1_k127_9541230_2 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.0009868 47.0
WLSH1_k127_9566176_0 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 586.0
WLSH1_k127_9566176_1 Outer membrane lipoprotein carrier protein LolA - - - 0.0000000000000000000000000000000000000001309 154.0
WLSH1_k127_9566255_0 4-alpha-glucanotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 436.0
WLSH1_k127_9566255_1 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 295.0
WLSH1_k127_9566255_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02236,K02278,K02506,K02654,K10966 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000006346 231.0
WLSH1_k127_9566255_3 PP-loop family K14058 - - 0.000000000000000000000000000000000000000000000000000000000000005632 224.0
WLSH1_k127_9566255_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000747 216.0
WLSH1_k127_9566255_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000003514 166.0
WLSH1_k127_9566255_6 Belongs to the UPF0235 family K09131 - - 0.0000000003788 63.0
WLSH1_k127_9642992_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.869e-212 678.0
WLSH1_k127_9642992_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.625e-198 636.0
WLSH1_k127_9642992_10 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000007433 194.0
WLSH1_k127_9642992_11 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.0000000000000000000000000000000000000000000003681 174.0
WLSH1_k127_9642992_12 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000004976 132.0
WLSH1_k127_9642992_13 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000000002599 83.0
WLSH1_k127_9642992_14 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.000000000006497 79.0
WLSH1_k127_9642992_15 Exonuclease VII small subunit K03602 - 3.1.11.6 0.0000007376 54.0
WLSH1_k127_9642992_16 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000002845 57.0
WLSH1_k127_9642992_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 580.0
WLSH1_k127_9642992_3 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 410.0
WLSH1_k127_9642992_4 glutamate-tRNA ligase activity K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 402.0
WLSH1_k127_9642992_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 347.0
WLSH1_k127_9642992_6 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 326.0
WLSH1_k127_9642992_7 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 325.0
WLSH1_k127_9642992_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000003266 216.0
WLSH1_k127_9642992_9 Fe-S iron-sulfur cluster assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000000000000000004679 204.0
WLSH1_k127_9662580_0 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 539.0
WLSH1_k127_9662580_1 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 422.0
WLSH1_k127_9662580_2 lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 336.0
WLSH1_k127_9662580_3 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000005312 134.0
WLSH1_k127_9700854_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 452.0
WLSH1_k127_9700854_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 296.0
WLSH1_k127_9700854_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001646 261.0
WLSH1_k127_9700854_3 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000004997 223.0
WLSH1_k127_9700854_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000003017 168.0
WLSH1_k127_9700854_5 negative regulation of translational initiation K05554,K14670 - - 0.00000000000000000000000000004541 121.0
WLSH1_k127_9700854_6 Enoyl-(Acyl carrier protein) reductase K00046 - 1.1.1.69 0.00000000000000000000000000005823 122.0
WLSH1_k127_9700854_7 Transcriptional regulator PadR-like family - - - 0.00000000004026 70.0
WLSH1_k127_9700854_8 Major Facilitator Superfamily - - - 0.000000000102 73.0
WLSH1_k127_9700854_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000009283 51.0
WLSH1_k127_9794857_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 475.0
WLSH1_k127_9794857_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000001448 247.0
WLSH1_k127_9794857_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000007941 117.0
WLSH1_k127_9799652_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 579.0
WLSH1_k127_9799652_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000003588 59.0
WLSH1_k127_980795_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 278.0
WLSH1_k127_980795_1 UvrB/uvrC motif K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000000000000000000000000002034 155.0
WLSH1_k127_980795_2 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 - 2.7.14.1 0.0000000000000000000000000000000000193 139.0
WLSH1_k127_9815374_0 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000001206 149.0
WLSH1_k127_9815374_1 Ami_2 - - - 0.00000000000000000000000000000132 128.0
WLSH1_k127_9815374_2 PFAM translation initiation factor SUI1 K03113 - - 0.000000000000000000000000002058 115.0
WLSH1_k127_9815374_3 - - - - 0.00000000000000003769 89.0
WLSH1_k127_9815374_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00001929 46.0
WLSH1_k127_990002_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 322.0
WLSH1_k127_990002_1 transmembrane transporter activity K02007,K02008 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000005051 202.0
WLSH1_k127_990002_2 TIGRFAM prepilin-type N-terminal cleavage methylation domain K02650 - - 0.0000000001559 68.0
WLSH1_k127_9945018_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 430.0
WLSH1_k127_9945018_1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 396.0
WLSH1_k127_9945018_2 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000008021 169.0
WLSH1_k127_9945018_3 Recombinase zinc beta ribbon domain K06400 - - 0.000000000000000000000000000000000000000001131 170.0
WLSH1_k127_9945018_4 Divergent PAP2 family K09775 - - 0.000000000000000000000000000000000008741 141.0
WLSH1_k127_9947077_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001434 256.0
WLSH1_k127_9947077_1 HD domain - - - 0.00000000000000000000009151 99.0