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Overview

ID MAG04192
Name WLSH2_bin.1
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Campylobacterota
Class Campylobacteria
Order Campylobacterales
Family Sulfurimonadaceae
Genus Sulfurimonas
Species
Assembly information
Completeness (%) 80.27
Contamination (%) 2.23
GC content (%) 38.0
N50 (bp) 5,363
Genome size (bp) 1,660,858

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1855

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10027669_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 1.645e-198 629.0
WLSH2_k127_10051695_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 513.0
WLSH2_k127_10051695_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001985 257.0
WLSH2_k127_10051695_2 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002257 256.0
WLSH2_k127_10076019_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 393.0
WLSH2_k127_10076019_1 Belongs to the pseudouridine synthase RluA family K06179,K06180 - 5.4.99.23,5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 359.0
WLSH2_k127_10076019_2 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006959 262.0
WLSH2_k127_10076019_3 endonuclease containing a URI domain K07461 - - 0.000000000000000000000000005278 112.0
WLSH2_k127_10084393_0 Belongs to the ClpA ClpB family K03694,K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 586.0
WLSH2_k127_10084393_1 Could be involved in insertion of integral membrane proteins into the membrane - - - 0.00000000000000000000000000000000000000003643 152.0
WLSH2_k127_10084393_2 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000000000001094 141.0
WLSH2_k127_10084393_3 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000002142 79.0
WLSH2_k127_10086430_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 470.0
WLSH2_k127_10086430_1 TIGRFAM SagB-type dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000002721 212.0
WLSH2_k127_10112340_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 546.0
WLSH2_k127_10112340_1 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 511.0
WLSH2_k127_10113889_0 PFAM tRNA synthetase class II (G H P and S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 517.0
WLSH2_k127_10113889_1 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 467.0
WLSH2_k127_10113889_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 394.0
WLSH2_k127_10116341_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1528.0
WLSH2_k127_10116341_1 AsmA-like C-terminal region - - - 0.0 1048.0
WLSH2_k127_10116341_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 8.442e-222 691.0
WLSH2_k127_10116341_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 548.0
WLSH2_k127_10116341_4 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000003268 198.0
WLSH2_k127_10116341_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000001075 188.0
WLSH2_k127_10119918_0 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 368.0
WLSH2_k127_10119918_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 308.0
WLSH2_k127_10119918_2 Rhodanese domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 279.0
WLSH2_k127_10119918_3 Transcriptional regulator K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003886 242.0
WLSH2_k127_10135308_0 PFAM TonB-dependent Receptor Plug Domain K02014 - - 1.171e-247 773.0
WLSH2_k127_10135308_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 2.367e-195 621.0
WLSH2_k127_10135308_2 Acyl-homoserine-lactone synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001102 255.0
WLSH2_k127_10140207_0 chemotaxis protein K03406 - - 4.355e-295 918.0
WLSH2_k127_10140207_1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 1.658e-211 661.0
WLSH2_k127_10140207_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 481.0
WLSH2_k127_10140207_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 286.0
WLSH2_k127_10140207_4 - - - - 0.000000000000000000000000000000000005219 138.0
WLSH2_k127_10140207_5 Sigma factor PP2C-like phosphatases - - - 0.00000000000000001554 83.0
WLSH2_k127_10146858_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 4.714e-236 734.0
WLSH2_k127_10146858_1 Belongs to the heme-copper respiratory oxidase family - - - 1.487e-195 617.0
WLSH2_k127_10146858_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 497.0
WLSH2_k127_10146858_3 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 442.0
WLSH2_k127_10146858_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 425.0
WLSH2_k127_10146858_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000001492 251.0
WLSH2_k127_10146858_6 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004025 239.0
WLSH2_k127_10146858_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000001274 142.0
WLSH2_k127_10146858_8 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000007233 68.0
WLSH2_k127_10149148_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 577.0
WLSH2_k127_10149148_1 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 522.0
WLSH2_k127_10149148_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 436.0
WLSH2_k127_10149148_3 cytochrome c class I - - - 0.000000000000000000000000000000000000000000000000009284 182.0
WLSH2_k127_10170688_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1292.0
WLSH2_k127_10170688_1 apolipoprotein N-acyltransferase K03820 - - 7.679e-198 625.0
WLSH2_k127_10170688_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 355.0
WLSH2_k127_10170688_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 343.0
WLSH2_k127_10170688_4 Preprotein translocase K03210 - - 0.00000000000000000000000000002591 124.0
WLSH2_k127_10170688_5 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000002516 106.0
WLSH2_k127_10172101_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.025e-261 810.0
WLSH2_k127_10172101_1 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000001632 207.0
WLSH2_k127_10281660_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1142.0
WLSH2_k127_10281660_1 Circularly permuted ATP-grasp type 2 - - - 1.763e-251 780.0
WLSH2_k127_10281660_10 Bacterial transglutaminase-like N-terminal region - - - 0.000000000000000000001757 96.0
WLSH2_k127_10281660_11 dna polymerase iii K02342 - 2.7.7.7 0.000000000000001176 78.0
WLSH2_k127_10281660_2 Succinylglutamate desuccinylase K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 489.0
WLSH2_k127_10281660_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 451.0
WLSH2_k127_10281660_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 355.0
WLSH2_k127_10281660_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 316.0
WLSH2_k127_10281660_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000001915 244.0
WLSH2_k127_10281660_7 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000358 226.0
WLSH2_k127_10281660_8 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000002432 209.0
WLSH2_k127_10281660_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000003741 108.0
WLSH2_k127_10286929_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 4.706e-237 736.0
WLSH2_k127_10286929_1 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 470.0
WLSH2_k127_10286929_2 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001919 260.0
WLSH2_k127_10289901_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1023.0
WLSH2_k127_10289901_1 Lipopolysaccharide-assembly - - - 0.00000000000000000000000005774 109.0
WLSH2_k127_10388195_0 PFAM biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 1e-323 992.0
WLSH2_k127_10388195_1 Molecular chaperone. Has ATPase activity K04079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 518.0
WLSH2_k127_10388195_3 - - - - 0.000000000000000000000000000000000000000000000000002381 183.0
WLSH2_k127_10388195_4 Domain of unknown function (DUF3817) - - - 0.00000000000000000000000000000000000000000001022 164.0
WLSH2_k127_10388195_5 PFAM biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 0.000000000000000000000000000000000000000001366 156.0
WLSH2_k127_10388195_6 COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000002327 154.0
WLSH2_k127_10388195_7 Oxaloacetate decarboxylase, gamma chain K01573 - 4.1.1.3 0.000000000000000000000000000000004484 129.0
WLSH2_k127_10507494_0 Acts as a magnesium transporter K06213 - - 4.584e-218 683.0
WLSH2_k127_10507494_1 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 405.0
WLSH2_k127_10507494_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000007121 175.0
WLSH2_k127_10507494_3 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000001903 117.0
WLSH2_k127_10507494_4 - - - - 0.000005778 50.0
WLSH2_k127_10509312_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.289e-262 812.0
WLSH2_k127_10509312_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.269e-258 803.0
WLSH2_k127_10509312_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 8.357e-244 767.0
WLSH2_k127_10509312_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 348.0
WLSH2_k127_10509312_4 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000285 282.0
WLSH2_k127_10509312_5 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001092 249.0
WLSH2_k127_10509312_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000001056 182.0
WLSH2_k127_10509312_8 - - - - 0.00000000000000000000000000000002641 127.0
WLSH2_k127_10510944_0 Abc transporter K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 419.0
WLSH2_k127_10510944_1 Methyltransferase domain K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 357.0
WLSH2_k127_10510944_2 PFAM MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000019 235.0
WLSH2_k127_10510944_3 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000165 231.0
WLSH2_k127_10522601_0 ATPase (AAA - - - 0.0 1039.0
WLSH2_k127_10522601_1 CMP dCMP deaminase K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000001936 223.0
WLSH2_k127_10522601_2 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000002303 177.0
WLSH2_k127_10522601_3 Long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000006289 143.0
WLSH2_k127_10522601_4 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000001745 132.0
WLSH2_k127_10542402_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 543.0
WLSH2_k127_10542402_1 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 368.0
WLSH2_k127_10542402_2 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 316.0
WLSH2_k127_10542402_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000003266 216.0
WLSH2_k127_10542402_4 - - - - 0.000000000000000000000000000000000000000000000001608 175.0
WLSH2_k127_10542402_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000001161 143.0
WLSH2_k127_10642275_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 516.0
WLSH2_k127_10642275_1 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 501.0
WLSH2_k127_10642275_2 Co Zn Cd efflux system component K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 430.0
WLSH2_k127_10642275_3 Redox-active disulfide protein - - - 0.00000000000000000000000000000006889 125.0
WLSH2_k127_10658873_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 531.0
WLSH2_k127_10658873_1 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 387.0
WLSH2_k127_10658873_2 Cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 357.0
WLSH2_k127_10658873_3 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 318.0
WLSH2_k127_1066860_0 fructose-bisphosphate aldolase K01624 - 4.1.2.13 1.072e-208 652.0
WLSH2_k127_1066860_1 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 436.0
WLSH2_k127_1066860_2 Hpt sensor hybrid histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 330.0
WLSH2_k127_1066860_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000228 240.0
WLSH2_k127_10691409_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 1.738e-206 644.0
WLSH2_k127_10691409_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 401.0
WLSH2_k127_10691409_2 7TMR-DISM extracellular 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 329.0
WLSH2_k127_10691409_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 307.0
WLSH2_k127_10691409_4 Biopolymer transporter ExbB K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001195 251.0
WLSH2_k127_10691409_5 biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000000000000000000000004674 213.0
WLSH2_k127_10691409_6 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000001549 126.0
WLSH2_k127_10722134_0 Hpt sensor hybrid histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 606.0
WLSH2_k127_10722134_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 407.0
WLSH2_k127_10771703_0 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 2.218e-302 929.0
WLSH2_k127_10771703_1 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 354.0
WLSH2_k127_10771703_2 PFAM Bacterial transcription activator, effector binding domain K13652 - - 0.00000000000006973 72.0
WLSH2_k127_107927_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 486.0
WLSH2_k127_107927_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 460.0
WLSH2_k127_107927_2 Belongs to the 'phage' integrase family K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 456.0
WLSH2_k127_107927_3 PFAM Fimbrial assembly family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003069 278.0
WLSH2_k127_107927_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000174 257.0
WLSH2_k127_107927_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007489 232.0
WLSH2_k127_107927_6 - - - - 0.000000000000000000000000000000000001762 145.0
WLSH2_k127_10804669_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 317.0
WLSH2_k127_10804669_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000216 228.0
WLSH2_k127_10804669_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000004668 176.0
WLSH2_k127_10815441_0 COG4775 Outer membrane protein protective antigen OMA87 K07278 - - 8.742e-237 743.0
WLSH2_k127_10815441_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 557.0
WLSH2_k127_10815441_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 508.0
WLSH2_k127_10815441_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003887 288.0
WLSH2_k127_10815441_4 - - - - 0.0000000000000000000000000000000007703 130.0
WLSH2_k127_10815441_5 acetolactate synthase K01653 - 2.2.1.6 0.00000000000000000114 85.0
WLSH2_k127_10844742_0 cation transport ATPase - - - 3.504e-235 746.0
WLSH2_k127_10844742_1 ATPase associated with various cellular activities, AAA_5 K07452 - - 0.000000000000000000000000000000000000000000000000000000000000008521 227.0
WLSH2_k127_10844742_2 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000000000000000000001766 177.0
WLSH2_k127_10855990_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 1.071e-276 869.0
WLSH2_k127_10855990_1 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 290.0
WLSH2_k127_10855990_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.0000000000000000000000000000283 118.0
WLSH2_k127_10864664_0 C-terminal domain of metallo-carboxypeptidase - - - 8.16e-217 679.0
WLSH2_k127_10864664_1 Pilus assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 306.0
WLSH2_k127_10864664_2 ErfK YbiS YcfS YnhG family protein - - - 0.000000000001687 67.0
WLSH2_k127_10871096_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1542.0
WLSH2_k127_10871096_1 Belongs to the NifD NifK NifE NifN family K02592 - - 1.168e-211 663.0
WLSH2_k127_10871096_10 (Lipo)protein K09860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008668 270.0
WLSH2_k127_10871096_11 Nitrogen fixation protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001001 244.0
WLSH2_k127_10871096_12 Dinitrogenase iron-molybdenum cofactor biosynthesis protein K02596 - - 0.000000000000000000000000000000000000000000000000000000004285 202.0
WLSH2_k127_10871096_13 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000003455 188.0
WLSH2_k127_10871096_14 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000000000000000000000005937 176.0
WLSH2_k127_10871096_15 PFAM NifZ K02597 - - 0.000000000000000000000000000000000000000000001167 168.0
WLSH2_k127_10871096_17 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000001224 131.0
WLSH2_k127_10871096_18 oxygen carrier activity K07216 - - 0.0000000000000000000000000000002556 126.0
WLSH2_k127_10871096_19 Nitrogen fixation protein NifW K02595 - - 0.0000000000000000000000000004899 114.0
WLSH2_k127_10871096_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 3.497e-209 651.0
WLSH2_k127_10871096_21 Nitrogen fixation protein NifW K02595 - - 0.0000000000224 63.0
WLSH2_k127_10871096_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 9.629e-201 630.0
WLSH2_k127_10871096_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 572.0
WLSH2_k127_10871096_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 554.0
WLSH2_k127_10871096_6 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 511.0
WLSH2_k127_10871096_7 cofactor biosynthesis protein NifE K02587 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 375.0
WLSH2_k127_10871096_8 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 304.0
WLSH2_k127_10871096_9 Low-potential electron donor to a number of redox enzymes K03839 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001354 276.0
WLSH2_k127_10889373_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1516.0
WLSH2_k127_10889373_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.886e-279 860.0
WLSH2_k127_10889373_10 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000000000000000000000003907 188.0
WLSH2_k127_10889373_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000003541 169.0
WLSH2_k127_10889373_12 - - - - 0.00000000000000000000000000000000000000000009154 162.0
WLSH2_k127_10889373_13 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000003997 113.0
WLSH2_k127_10889373_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.309e-227 707.0
WLSH2_k127_10889373_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 3.224e-224 702.0
WLSH2_k127_10889373_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 1.963e-205 643.0
WLSH2_k127_10889373_5 PAS domain K09155 - - 4.567e-201 627.0
WLSH2_k127_10889373_6 Belongs to the pseudouridine synthase RluA family K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 518.0
WLSH2_k127_10889373_7 phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 326.0
WLSH2_k127_10889373_8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 300.0
WLSH2_k127_10889373_9 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002715 259.0
WLSH2_k127_10899503_0 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 401.0
WLSH2_k127_10899503_1 - - - - 0.000000000000000000000000000000000000000000001462 168.0
WLSH2_k127_10899503_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000001719 115.0
WLSH2_k127_10899503_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000007503 74.0
WLSH2_k127_10899503_4 - - - - 0.00000000000002195 77.0
WLSH2_k127_10908358_0 Peptidase M48 K06013 - 3.4.24.84 1.457e-226 706.0
WLSH2_k127_10908358_1 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.000000000000000000000000000000000000000001838 160.0
WLSH2_k127_10940468_0 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 492.0
WLSH2_k127_10940468_1 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 438.0
WLSH2_k127_10940468_2 Belongs to the ATPase B chain family K02109 - - 0.0000000000000000000000000000000000000000000000006041 176.0
WLSH2_k127_10970120_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 456.0
WLSH2_k127_10970120_1 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 319.0
WLSH2_k127_10997833_0 flagellar motor switch protein K02416 - - 4.451e-202 632.0
WLSH2_k127_10997833_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 5.938e-201 628.0
WLSH2_k127_10997833_2 Belongs to the ParA family K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 501.0
WLSH2_k127_10997833_3 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 416.0
WLSH2_k127_10997833_4 Belongs to the sigma-70 factor family K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 400.0
WLSH2_k127_10997833_5 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 389.0
WLSH2_k127_10997833_6 flagellar biosynthesis K02404 - - 0.00000000000000000000000000000000000000000000000000000000000000007435 222.0
WLSH2_k127_110202_0 diguanylate cyclase - - - 3.263e-295 917.0
WLSH2_k127_110202_1 TonB-dependent receptor K02014 - - 3.421e-214 681.0
WLSH2_k127_110202_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 321.0
WLSH2_k127_110202_3 transformation system protein K02242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 282.0
WLSH2_k127_110202_4 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000009137 196.0
WLSH2_k127_110202_5 - - - - 0.000000000007603 71.0
WLSH2_k127_11056445_0 lipopolysaccharide heptosyltransferase K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 560.0
WLSH2_k127_11056445_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005 246.0
WLSH2_k127_11056445_2 Phosphate acetyl butaryl transferase K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000001563 155.0
WLSH2_k127_11056445_3 ABC transporter K11085 - - 0.000004785 48.0
WLSH2_k127_11079700_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.105e-316 968.0
WLSH2_k127_11079700_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000007817 92.0
WLSH2_k127_11115012_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 531.0
WLSH2_k127_11115012_1 TrkA-N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009828 255.0
WLSH2_k127_11115012_2 potassium channel protein K10716 - - 0.0000000000000000000000000000000000000000000000000005039 187.0
WLSH2_k127_11115012_3 transporter K14445 - - 0.0000000000001196 72.0
WLSH2_k127_11128490_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.466e-315 968.0
WLSH2_k127_11128490_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.051e-294 906.0
WLSH2_k127_11128490_10 Belongs to the ATPase B chain family K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000001564 235.0
WLSH2_k127_11128490_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000000000000001639 222.0
WLSH2_k127_11128490_12 transport protein K03559 - - 0.000000000000000000000000000004194 123.0
WLSH2_k127_11128490_13 Belongs to the ParB family K03497 - - 0.000001356 51.0
WLSH2_k127_11128490_2 Involved in the TonB-independent uptake of proteins K03641 - - 7.422e-222 692.0
WLSH2_k127_11128490_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 533.0
WLSH2_k127_11128490_4 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 367.0
WLSH2_k127_11128490_5 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 350.0
WLSH2_k127_11128490_6 MotA TolQ ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 318.0
WLSH2_k127_11128490_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 284.0
WLSH2_k127_11128490_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001806 280.0
WLSH2_k127_11128490_9 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004267 255.0
WLSH2_k127_11142345_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000009687 235.0
WLSH2_k127_11142345_1 TIGRFAM SagB-type dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000003638 177.0
WLSH2_k127_11185317_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 9.934e-256 789.0
WLSH2_k127_11185317_1 2-acylglycerophosphoethanolamine acyltransferase K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000002004 225.0
WLSH2_k127_11185317_2 Signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000004368 186.0
WLSH2_k127_111950_0 Histidine kinase K02484 - 2.7.13.3 1.215e-241 750.0
WLSH2_k127_111950_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.617e-235 731.0
WLSH2_k127_111950_10 Ferritin K03594 - 1.16.3.1 0.00000000000000000001024 91.0
WLSH2_k127_111950_11 - - - - 0.000000000000001137 83.0
WLSH2_k127_111950_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 4.772e-204 636.0
WLSH2_k127_111950_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 595.0
WLSH2_k127_111950_4 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 512.0
WLSH2_k127_111950_5 response regulator K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 417.0
WLSH2_k127_111950_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 394.0
WLSH2_k127_111950_7 Receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 361.0
WLSH2_k127_111950_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 296.0
WLSH2_k127_111950_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000198 100.0
WLSH2_k127_11201818_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 524.0
WLSH2_k127_11201818_1 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000004517 188.0
WLSH2_k127_11201818_2 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000001436 147.0
WLSH2_k127_11202445_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 449.0
WLSH2_k127_11202445_1 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000004522 170.0
WLSH2_k127_11202445_2 involved in chromosome partitioning K03496 - - 0.00000000003664 64.0
WLSH2_k127_11213804_0 Belongs to the DegT DnrJ EryC1 family K15910 - 2.6.1.34 1.502e-206 646.0
WLSH2_k127_11213804_1 Mitochondrial degradasome RNA helicase subunit C terminal K17675 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 503.0
WLSH2_k127_11213804_2 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 419.0
WLSH2_k127_11213804_3 Transferase K15915 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 355.0
WLSH2_k127_11213804_4 O-acyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000006908 203.0
WLSH2_k127_11222991_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1439.0
WLSH2_k127_11222991_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 2.025e-194 610.0
WLSH2_k127_11222991_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 583.0
WLSH2_k127_11222991_3 (EAL) domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 546.0
WLSH2_k127_11222991_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 304.0
WLSH2_k127_11222991_5 PAS domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004962 276.0
WLSH2_k127_11222991_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001054 251.0
WLSH2_k127_11222991_7 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.000000000000000000000000000000000000001399 152.0
WLSH2_k127_11268349_0 Glycosyl transferase family, helical bundle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 529.0
WLSH2_k127_11268349_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K16066 - 1.1.1.381 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 456.0
WLSH2_k127_11268349_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000001115 125.0
WLSH2_k127_11279384_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 0.0 1025.0
WLSH2_k127_11279384_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.242e-259 801.0
WLSH2_k127_11279384_2 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 3.838e-215 671.0
WLSH2_k127_11279384_3 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 383.0
WLSH2_k127_11279384_4 hydrolase K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 293.0
WLSH2_k127_11279384_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009427 247.0
WLSH2_k127_11279384_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004788 243.0
WLSH2_k127_11326122_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 322.0
WLSH2_k127_11326122_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000001104 68.0
WLSH2_k127_11340704_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.0 1171.0
WLSH2_k127_11340704_1 chaperone-mediated protein folding - - - 0.0 1095.0
WLSH2_k127_11340704_2 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1049.0
WLSH2_k127_11340704_3 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 1.642e-301 928.0
WLSH2_k127_11340704_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 5.106e-297 915.0
WLSH2_k127_11340704_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 1.749e-197 617.0
WLSH2_k127_11340704_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 432.0
WLSH2_k127_11340704_7 ORF6N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 337.0
WLSH2_k127_11340704_8 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 304.0
WLSH2_k127_11340704_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001444 198.0
WLSH2_k127_11393712_0 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 502.0
WLSH2_k127_11393712_1 dna polymerase iii K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 369.0
WLSH2_k127_11400146_0 Glycolate oxidase subunit K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 598.0
WLSH2_k127_11400146_1 Plasminogen-binding protein pgbA N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 383.0
WLSH2_k127_11453863_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1267.0
WLSH2_k127_11453863_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000000000004001 168.0
WLSH2_k127_11486984_0 Flagellar hook protein flgE K02390 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.0 1244.0
WLSH2_k127_11486984_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 554.0
WLSH2_k127_11486984_2 Flagellar basal body protein K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 282.0
WLSH2_k127_11490895_0 Nitrogenase cofactor biosynthesis protein NifB K02585 - - 9.294e-217 677.0
WLSH2_k127_11490895_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002506 222.0
WLSH2_k127_11490895_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000007573 206.0
WLSH2_k127_11490895_3 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000002142 188.0
WLSH2_k127_11490895_4 thioredoxin peroxidase activity K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000002747 170.0
WLSH2_k127_11490895_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000004387 133.0
WLSH2_k127_1168921_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.084e-299 923.0
WLSH2_k127_1168921_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 529.0
WLSH2_k127_1168921_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 321.0
WLSH2_k127_1168921_3 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002545 268.0
WLSH2_k127_1168921_4 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000002078 162.0
WLSH2_k127_1168921_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000002206 93.0
WLSH2_k127_1262959_0 chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 480.0
WLSH2_k127_1262959_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 361.0
WLSH2_k127_1284064_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 3.409e-318 980.0
WLSH2_k127_1284064_1 ATPase (AAA K01714,K12283 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 381.0
WLSH2_k127_1284064_2 Type II secretion system K02455,K12278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 317.0
WLSH2_k127_1284064_3 proteins homologs of microcin C7 resistance protein MccF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005636 259.0
WLSH2_k127_1284064_4 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000006417 207.0
WLSH2_k127_1284064_5 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.000000000000000000000000000000000000000004141 166.0
WLSH2_k127_1290456_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 480.0
WLSH2_k127_1290456_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 405.0
WLSH2_k127_1290456_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 293.0
WLSH2_k127_1290456_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000000000000005987 231.0
WLSH2_k127_1290456_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000000000000003043 155.0
WLSH2_k127_1290456_5 Belongs to the UPF0109 family K06960 - - 0.0000001155 56.0
WLSH2_k127_1338391_0 Pilus assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 443.0
WLSH2_k127_1338391_1 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 346.0
WLSH2_k127_1338391_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001152 279.0
WLSH2_k127_1356660_0 PFAM dUTPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 372.0
WLSH2_k127_1356660_1 ABC transporter, ATP-binding protein K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 310.0
WLSH2_k127_1356660_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000002285 141.0
WLSH2_k127_1362703_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1258.0
WLSH2_k127_1362703_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 1.984e-203 642.0
WLSH2_k127_1362703_2 phosphohydrolase (DHH superfamily) K07097 - - 3.573e-197 618.0
WLSH2_k127_1362703_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 409.0
WLSH2_k127_1362703_4 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 346.0
WLSH2_k127_1362703_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001272 240.0
WLSH2_k127_1362703_6 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000002335 208.0
WLSH2_k127_1362703_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000000002092 160.0
WLSH2_k127_1366404_0 ribosomal protein S1 K02945 - - 0.0 1020.0
WLSH2_k127_1366404_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 6.414e-320 983.0
WLSH2_k127_1366404_2 COG0841 Cation multidrug efflux pump - - - 1.902e-314 968.0
WLSH2_k127_1366404_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.967e-300 925.0
WLSH2_k127_1366404_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 427.0
WLSH2_k127_1366404_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001525 272.0
WLSH2_k127_1366404_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 253.0
WLSH2_k127_1366404_7 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000004162 206.0
WLSH2_k127_1386890_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1269.0
WLSH2_k127_1386890_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000004323 205.0
WLSH2_k127_1386890_2 COG0474 Cation transport ATPase - - - 0.000000000000000000000000000000000000000003071 157.0
WLSH2_k127_14471_0 Belongs to the DNA mismatch repair MutS family K03555 - - 2.52e-280 865.0
WLSH2_k127_14471_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 1.689e-199 625.0
WLSH2_k127_14471_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 443.0
WLSH2_k127_14471_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000000000002363 219.0
WLSH2_k127_14471_4 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000000000000000000000000000008986 194.0
WLSH2_k127_14471_5 - - - - 0.00000000002227 70.0
WLSH2_k127_1471435_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 410.0
WLSH2_k127_1471435_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 404.0
WLSH2_k127_1632762_0 Histidine kinase - - - 0.0 1079.0
WLSH2_k127_1632762_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 1.717e-312 964.0
WLSH2_k127_1632762_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 378.0
WLSH2_k127_1632762_3 - - - - 0.00000000000000000000000000000000000000000000000009854 181.0
WLSH2_k127_1632762_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03776 - - 0.00000000000000000000000000000000000000000000008925 171.0
WLSH2_k127_173430_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 359.0
WLSH2_k127_173430_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000502 268.0
WLSH2_k127_1792830_0 UPF0313 protein - - - 2.033e-257 795.0
WLSH2_k127_1792830_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 518.0
WLSH2_k127_1792830_2 S4 domain protein - - - 0.000000000000000000000000000000000009251 136.0
WLSH2_k127_1810712_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 1.172e-284 876.0
WLSH2_k127_1810712_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 457.0
WLSH2_k127_1810712_2 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 308.0
WLSH2_k127_1810712_3 ABC transporter, ATP-binding protein K15738 - - 0.00000000000000000000000000000000000000000000000000000000006976 206.0
WLSH2_k127_1810712_4 Belongs to the Fur family K03711 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000006501 124.0
WLSH2_k127_1846822_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 602.0
WLSH2_k127_1846822_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 431.0
WLSH2_k127_1846822_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 295.0
WLSH2_k127_1846822_3 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000001231 160.0
WLSH2_k127_1856339_0 Sel1-like repeats. - - - 0.00000000003 73.0
WLSH2_k127_1856339_1 diguanylate cyclase - - - 0.000004942 58.0
WLSH2_k127_1939688_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 3.946e-239 754.0
WLSH2_k127_1939688_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.87e-229 714.0
WLSH2_k127_1939688_2 Co-chaperone-curved DNA binding protein A K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 505.0
WLSH2_k127_1939688_3 Transcriptional regulator K13640 - - 0.0000000000000000000000000000000000000000000000000000000000000000007494 228.0
WLSH2_k127_1939688_4 Belongs to the peptidase M48B family K03799 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000005036 188.0
WLSH2_k127_2001278_0 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 506.0
WLSH2_k127_2001278_1 membrane K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 503.0
WLSH2_k127_2001278_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 299.0
WLSH2_k127_2001278_4 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 293.0
WLSH2_k127_2001278_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006172 259.0
WLSH2_k127_2021199_0 Belongs to the DNA mismatch repair MutS family K03555 - - 0.0 1041.0
WLSH2_k127_2102243_0 dihydropteroate synthase K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 533.0
WLSH2_k127_2102243_1 DNA polymerase III K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009372 268.0
WLSH2_k127_2109892_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 2.362e-235 732.0
WLSH2_k127_2109892_1 ABC transporter, ATP-binding protein K01990,K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 440.0
WLSH2_k127_2109892_2 Virulence protein RhuM family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 400.0
WLSH2_k127_2109892_3 ORF6N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 391.0
WLSH2_k127_2109892_4 tigr02757 - - - 0.000000000000000000000000000000000000000000001542 165.0
WLSH2_k127_2109892_5 ATPase or kinase K06925 - - 0.00000000000000000007141 89.0
WLSH2_k127_2113954_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1221.0
WLSH2_k127_2113954_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 3.102e-286 881.0
WLSH2_k127_2113954_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 571.0
WLSH2_k127_2113954_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000473 235.0
WLSH2_k127_2113954_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000002656 90.0
WLSH2_k127_2135751_0 ATP citrate synthase K15230 - 2.3.3.8 0.0 1102.0
WLSH2_k127_2135751_1 flagellar hook-associated protein K02396 - - 2.748e-290 902.0
WLSH2_k127_2135751_2 Belongs to the succinate malate CoA ligase beta subunit family K15231 - 2.3.3.8 1.097e-271 838.0
WLSH2_k127_2135751_3 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 540.0
WLSH2_k127_2135751_4 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034,K12370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 464.0
WLSH2_k127_2135751_5 Anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 347.0
WLSH2_k127_2135751_6 Tfp pilus assembly protein FimT - - - 0.00000000000000000000000000000000000000000000000000000028 201.0
WLSH2_k127_2135751_7 - - - - 0.000000000000005762 74.0
WLSH2_k127_218193_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 2.96e-211 660.0
WLSH2_k127_218193_1 Putative glycosyl hydrolase domain - - - 0.00000000000006977 73.0
WLSH2_k127_2182717_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2656.0
WLSH2_k127_2182717_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1214.0
WLSH2_k127_2182717_10 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 334.0
WLSH2_k127_2182717_11 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000006116 263.0
WLSH2_k127_2182717_12 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000001611 246.0
WLSH2_k127_2182717_13 DnaK suppressor protein K06204 - - 0.0000000000000000000000000000000000000000000000000000000000001956 212.0
WLSH2_k127_2182717_15 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000000000000000000006247 193.0
WLSH2_k127_2182717_2 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 3.429e-286 881.0
WLSH2_k127_2182717_3 - - - - 3.341e-204 639.0
WLSH2_k127_2182717_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 562.0
WLSH2_k127_2182717_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 509.0
WLSH2_k127_2182717_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 489.0
WLSH2_k127_2182717_7 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 374.0
WLSH2_k127_2182717_8 flagellar - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 372.0
WLSH2_k127_2182717_9 RecO N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 348.0
WLSH2_k127_2251832_0 peptidase U32 family K08303 - - 3.222e-266 822.0
WLSH2_k127_2251832_1 Protein of unknown function (DUF3972) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 294.0
WLSH2_k127_2251832_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 291.0
WLSH2_k127_2251832_3 - - - - 0.00000000000000000000000000000000000005953 142.0
WLSH2_k127_2251832_4 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000356 100.0
WLSH2_k127_2299286_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 366.0
WLSH2_k127_2299286_2 metallophosphoesterase K09769 - - 0.000000000000000000000000000000001526 129.0
WLSH2_k127_2299286_3 Histidine kinase - - - 0.00000000000000001503 83.0
WLSH2_k127_2369653_0 Type I secretion system ATPase K12541 - - 0.0 1104.0
WLSH2_k127_2369653_1 HlyD membrane-fusion protein of T1SS K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 417.0
WLSH2_k127_2369653_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 252.0
WLSH2_k127_2369653_3 Cobalamin biosynthesis protein CobT VWA domain K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000001856 82.0
WLSH2_k127_2383137_0 Flagellar Assembly Protein A - - - 1.45e-264 824.0
WLSH2_k127_2383137_1 phosphate transporter K03306 - - 4.659e-253 786.0
WLSH2_k127_2383137_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 297.0
WLSH2_k127_2383137_3 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000000000000000000000000000000005177 164.0
WLSH2_k127_2383137_4 DNA-binding protein - - - 0.000000000000000000000000000000000000001592 147.0
WLSH2_k127_2445936_0 2-acylglycerophosphoethanolamine acyltransferase K05939 - 2.3.1.40,6.2.1.20 9.637e-305 942.0
WLSH2_k127_2445936_1 Family of unknown function (DUF695) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 364.0
WLSH2_k127_2445936_2 unfolded protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001574 263.0
WLSH2_k127_2445936_3 Nucleoside-specific channel-forming protein, Tsx - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006693 255.0
WLSH2_k127_2524745_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1087.0
WLSH2_k127_2524745_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 571.0
WLSH2_k127_2530182_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.137e-264 818.0
WLSH2_k127_2530182_1 Pyridine nucleotide-disulphide oxidoreductase - - - 2.556e-248 770.0
WLSH2_k127_2530182_10 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 306.0
WLSH2_k127_2530182_11 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008315 250.0
WLSH2_k127_2530182_12 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000007581 233.0
WLSH2_k127_2530182_13 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000000000000000005853 149.0
WLSH2_k127_2530182_14 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000005989 147.0
WLSH2_k127_2530182_15 Protein of unknown function (DUF2892) - - - 0.000000000000000000001557 94.0
WLSH2_k127_2530182_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.941e-227 710.0
WLSH2_k127_2530182_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 1.871e-208 650.0
WLSH2_k127_2530182_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 593.0
WLSH2_k127_2530182_5 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 539.0
WLSH2_k127_2530182_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 399.0
WLSH2_k127_2530182_7 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 399.0
WLSH2_k127_2530182_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 374.0
WLSH2_k127_2530182_9 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 342.0
WLSH2_k127_2543048_0 Cytochrome K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 579.0
WLSH2_k127_2543048_1 COG0433 Predicted ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 450.0
WLSH2_k127_2543048_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 374.0
WLSH2_k127_2543048_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 350.0
WLSH2_k127_25446_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1512.0
WLSH2_k127_25446_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1019.0
WLSH2_k127_25446_10 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000505 236.0
WLSH2_k127_25446_12 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000008814 69.0
WLSH2_k127_25446_2 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 573.0
WLSH2_k127_25446_3 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 458.0
WLSH2_k127_25446_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 414.0
WLSH2_k127_25446_5 abc transporter atp-binding protein K02031,K15587 - 3.6.3.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 352.0
WLSH2_k127_25446_7 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 307.0
WLSH2_k127_25446_8 nucleotide-binding protein implicated in inhibition of septum formation K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 284.0
WLSH2_k127_25446_9 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001118 265.0
WLSH2_k127_2545610_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.265e-314 964.0
WLSH2_k127_2545610_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 543.0
WLSH2_k127_2545610_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000007361 161.0
WLSH2_k127_2545610_3 MOSC domain - - - 0.0000000000000003609 79.0
WLSH2_k127_2565548_0 Domain of unknown function (DUF4055) - - - 0.000000000000000000000000000000000000000000000000000000003076 214.0
WLSH2_k127_2565548_1 Head morphogenesis protein - - - 0.000000000000007021 83.0
WLSH2_k127_2591969_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 8.924e-194 608.0
WLSH2_k127_2591969_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 567.0
WLSH2_k127_2591969_2 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 296.0
WLSH2_k127_2591969_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 289.0
WLSH2_k127_2591969_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000003613 147.0
WLSH2_k127_2602231_0 Chemotaxis phosphatase CheX - - - 4.534e-256 794.0
WLSH2_k127_2602231_1 Potassium channel protein K10716 - - 1.9e-218 680.0
WLSH2_k127_2602231_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 556.0
WLSH2_k127_2602231_3 dna polymerase iii K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 420.0
WLSH2_k127_2602231_4 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 416.0
WLSH2_k127_2602231_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 407.0
WLSH2_k127_2602231_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 336.0
WLSH2_k127_2602231_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000001318 158.0
WLSH2_k127_2602231_8 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000008459 116.0
WLSH2_k127_2602231_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000001407 96.0
WLSH2_k127_2629937_0 NMT1/THI5 like - - - 0.0 1057.0
WLSH2_k127_2629937_1 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 610.0
WLSH2_k127_2629937_2 fumarate reductase, iron-sulfur protein K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 374.0
WLSH2_k127_2629937_3 Belongs to the 'phage' integrase family K14059 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 309.0
WLSH2_k127_2629937_4 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 288.0
WLSH2_k127_2629937_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001933 273.0
WLSH2_k127_2629937_6 metal cluster binding - - - 0.0000000000000000000000000000000176 127.0
WLSH2_k127_2629937_7 Bacteriophage replication gene A protein (GPA) - - - 0.00000002759 59.0
WLSH2_k127_2631969_0 Thiol disulfide interchange protein K04084 - 1.8.1.8 5.993e-269 838.0
WLSH2_k127_2631969_1 Highly conserved protein containing a thioredoxin domain K06888 - - 2.515e-227 708.0
WLSH2_k127_2631969_2 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 9.493e-207 646.0
WLSH2_k127_2631969_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 597.0
WLSH2_k127_2631969_4 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 512.0
WLSH2_k127_2631969_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 408.0
WLSH2_k127_2631969_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000003409 213.0
WLSH2_k127_2631969_7 that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - 0.000000000000000000000000000000000000000855 158.0
WLSH2_k127_2710379_0 Radical SAM - - - 1.636e-271 840.0
WLSH2_k127_2710379_1 LapD/MoxY periplasmic domain - - - 1.515e-199 632.0
WLSH2_k127_2710379_2 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 292.0
WLSH2_k127_2716878_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 447.0
WLSH2_k127_2716878_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003268 281.0
WLSH2_k127_2808632_0 DNA helicase K03657 - 3.6.4.12 0.0 1245.0
WLSH2_k127_2808632_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 571.0
WLSH2_k127_2808632_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 501.0
WLSH2_k127_2808632_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 484.0
WLSH2_k127_2808632_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000001559 258.0
WLSH2_k127_2808632_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002765 249.0
WLSH2_k127_2808632_6 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000002477 203.0
WLSH2_k127_2808632_7 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000004994 199.0
WLSH2_k127_2838294_0 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 330.0
WLSH2_k127_2838294_1 acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003059 271.0
WLSH2_k127_2838294_3 Lipopolysaccharide transport periplasmic protein lpta K09774 - - 0.00000000000000000000000000000000000000000000000000000000001282 210.0
WLSH2_k127_2838294_4 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000007353 187.0
WLSH2_k127_2838294_6 penicillin-binding protein K05515 - 3.4.16.4 0.000000000000000000000000000000000000002787 147.0
WLSH2_k127_2850683_0 COG1252 NADH dehydrogenase FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 527.0
WLSH2_k127_2850683_1 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 289.0
WLSH2_k127_2895425_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 1.904e-255 789.0
WLSH2_k127_2895425_1 anthranilate synthase component K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 526.0
WLSH2_k127_2895425_2 Domain of unknown function (DUF1882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009101 356.0
WLSH2_k127_2895425_3 Cell division protein K03591,K03749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004468 276.0
WLSH2_k127_29400_0 Na H antiporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 604.0
WLSH2_k127_29400_1 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 408.0
WLSH2_k127_29400_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 372.0
WLSH2_k127_29400_3 Protein of unknown function (DUF819) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 374.0
WLSH2_k127_29400_4 N-Acetylmuramoyl-L-alanine amidase K01207,K01447,K11066 - 3.2.1.52,3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 306.0
WLSH2_k127_29400_6 COGs COG3786 conserved - - - 0.0000002377 54.0
WLSH2_k127_2986388_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 6.355e-249 772.0
WLSH2_k127_2986388_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 592.0
WLSH2_k127_2986388_2 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001925 252.0
WLSH2_k127_2986388_3 PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001431 238.0
WLSH2_k127_2986388_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000003446 218.0
WLSH2_k127_2986388_5 Nitrogen fixation protein NifU - - - 0.00000000000000000000000000000000000000000000000001666 179.0
WLSH2_k127_2986388_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000001054 159.0
WLSH2_k127_2986388_7 - - - - 0.0000000000000000000000000000000000002029 148.0
WLSH2_k127_2986388_8 ribosomal protein L17 K02879 - - 0.00000000000000000000003031 98.0
WLSH2_k127_2989302_0 Abc transporter K02035 - - 1.749e-283 875.0
WLSH2_k127_2989302_1 pyruvate ferredoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 354.0
WLSH2_k127_2989302_2 Hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 356.0
WLSH2_k127_2989302_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 278.0
WLSH2_k127_2989302_4 pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002463 264.0
WLSH2_k127_2989302_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007629 243.0
WLSH2_k127_2989302_6 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000333 215.0
WLSH2_k127_2989302_7 NlpC/P60 family K13694,K13695 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000001563 196.0
WLSH2_k127_2989302_8 diguanylate cyclase K21020 - 2.7.7.65 0.00000000000000000000000000000000000000567 164.0
WLSH2_k127_2989302_9 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.000000000000000000361 95.0
WLSH2_k127_3005088_0 Potassium uptake protein K03498 - - 8.858e-221 691.0
WLSH2_k127_3005088_1 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 357.0
WLSH2_k127_3005088_2 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
WLSH2_k127_3005088_3 (HIT) family - - - 0.00000000000000000000000000000000000000000000000000000000001122 208.0
WLSH2_k127_3005088_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000004952 199.0
WLSH2_k127_3005088_5 Putative mono-oxygenase ydhR - - - 0.0000000000000000000000000000000000008292 141.0
WLSH2_k127_3014106_0 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 2.816e-260 805.0
WLSH2_k127_3014106_1 May be involved in recombinational repair of damaged DNA K03631 - - 3.015e-237 742.0
WLSH2_k127_3014106_10 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000001335 96.0
WLSH2_k127_3014106_11 Domain of unknown function (DUF4136) - - - 0.00005899 51.0
WLSH2_k127_3014106_2 lytic murein transglycosylase K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 578.0
WLSH2_k127_3014106_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 489.0
WLSH2_k127_3014106_4 hydrolase, TatD K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 418.0
WLSH2_k127_3014106_5 Imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 340.0
WLSH2_k127_3014106_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 340.0
WLSH2_k127_3014106_7 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001857 276.0
WLSH2_k127_3014106_8 Type VI secretion protein, VC_A0107 family K11901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001617 258.0
WLSH2_k127_30167_0 TaqI-like C-terminal specificity domain - - - 7.195e-283 883.0
WLSH2_k127_30167_1 - - - - 0.00000000003298 64.0
WLSH2_k127_3028841_0 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1296.0
WLSH2_k127_3028841_1 ADP-L-glycero-D-manno-heptose-6-epimerase K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 608.0
WLSH2_k127_3028841_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009318 271.0
WLSH2_k127_3028841_3 cytochrome - - - 0.0000000000000000000000000000000000000000002433 159.0
WLSH2_k127_3028841_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000007413 151.0
WLSH2_k127_3028841_5 Cytochrome oxidase maturation protein - - - 0.00000000000000000000000000000002777 126.0
WLSH2_k127_3028841_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000001888 123.0
WLSH2_k127_3028841_7 cytochrome - - - 0.0000000000000000000000000000003863 124.0
WLSH2_k127_3028841_8 asparaginase activity K01424 - 3.5.1.1 0.00000000000002608 79.0
WLSH2_k127_3042962_0 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 386.0
WLSH2_k127_3042962_1 protein conserved in bacteria K09859 - - 0.00000000000000000000000000000000000000000000000000000000000000001889 236.0
WLSH2_k127_3042962_2 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000245 225.0
WLSH2_k127_3042962_3 - - - - 0.000000002435 68.0
WLSH2_k127_3050873_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1254.0
WLSH2_k127_3050873_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 4.837e-220 686.0
WLSH2_k127_3050873_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000002123 228.0
WLSH2_k127_3112586_0 Polysaccharide biosynthesis protein K15912 - 4.2.1.135 1.317e-248 773.0
WLSH2_k127_3112586_1 Glutathionylspermidine synthase - - - 0.0000000000000000000000000000000000000000000000000000002796 194.0
WLSH2_k127_3120105_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.574e-213 665.0
WLSH2_k127_3120105_1 DNA replication regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 342.0
WLSH2_k127_3132984_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1809.0
WLSH2_k127_3132984_1 COG2199 FOG GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 589.0
WLSH2_k127_3132984_2 TIGRFAM MauM NapG family ferredoxin-type protein K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 492.0
WLSH2_k127_3132984_3 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 478.0
WLSH2_k127_3132984_4 Ferredoxin-type protein, NapH MauN family K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 463.0
WLSH2_k127_3132984_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 438.0
WLSH2_k127_3132984_6 - catabolite gene activator and regulatory subunit of cAMP-dependent protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 357.0
WLSH2_k127_3132984_7 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 346.0
WLSH2_k127_3167686_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1474.0
WLSH2_k127_3167686_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 399.0
WLSH2_k127_3303526_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 5.2e-204 638.0
WLSH2_k127_3303526_1 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 408.0
WLSH2_k127_3321277_0 molybdopterin biosynthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 565.0
WLSH2_k127_3321277_1 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000141 218.0
WLSH2_k127_3350072_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 357.0
WLSH2_k127_3350072_1 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 348.0
WLSH2_k127_3372667_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1009.0
WLSH2_k127_3372667_1 Belongs to the GARS family K01945 - 6.3.4.13 2.934e-255 790.0
WLSH2_k127_3372667_2 COG1055 Na H antiporter NhaD and related arsenite - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 515.0
WLSH2_k127_3372667_3 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 329.0
WLSH2_k127_3372667_4 RDD family - - - 0.0000002052 55.0
WLSH2_k127_3388497_0 UDP-N-acetylglucosamine 2-epimerase K18429 GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016787,GO:0016798,GO:0044238,GO:0071704,GO:1901576 3.2.1.184 1.022e-207 650.0
WLSH2_k127_3388497_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 538.0
WLSH2_k127_3388497_2 NeuB family K18430 GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016740,GO:0016765,GO:0044238,GO:0071704,GO:1901576 2.5.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 488.0
WLSH2_k127_3388497_3 Cytidylyltransferase K18431 - 2.7.7.82 0.0000000000000000000000000000000000009139 139.0
WLSH2_k127_3388497_4 NeuB family K18430 GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016740,GO:0016765,GO:0044238,GO:0071704,GO:1901576 2.5.1.101 0.0000000000000001341 79.0
WLSH2_k127_3443584_0 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 509.0
WLSH2_k127_3443584_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 454.0
WLSH2_k127_3450864_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 5.652e-196 613.0
WLSH2_k127_3450864_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 608.0
WLSH2_k127_3472075_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 570.0
WLSH2_k127_3472075_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 446.0
WLSH2_k127_3532386_0 TonB-dependent copper receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 505.0
WLSH2_k127_3532386_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 432.0
WLSH2_k127_3532386_2 GGDEF domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000802 167.0
WLSH2_k127_3571352_0 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 380.0
WLSH2_k127_3571352_1 Chemotaxis protein CheY K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 294.0
WLSH2_k127_357366_0 MMPL family K07003 - - 0.0 1026.0
WLSH2_k127_357366_1 - - - - 0.0003798 44.0
WLSH2_k127_3678748_0 Phage terminase large subunit (GpA) - - - 0.000000000001696 81.0
WLSH2_k127_3729781_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 474.0
WLSH2_k127_3729781_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 417.0
WLSH2_k127_3729781_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 401.0
WLSH2_k127_3729781_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 350.0
WLSH2_k127_3729781_4 Aminotransferase K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000003518 231.0
WLSH2_k127_3729781_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000002838 214.0
WLSH2_k127_3729781_7 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000004959 132.0
WLSH2_k127_3742972_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 582.0
WLSH2_k127_3742972_1 NosL - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 497.0
WLSH2_k127_3742972_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 437.0
WLSH2_k127_3742972_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 369.0
WLSH2_k127_3742972_4 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 337.0
WLSH2_k127_3742972_5 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 309.0
WLSH2_k127_3742972_6 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000001455 244.0
WLSH2_k127_3742972_7 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000001085 221.0
WLSH2_k127_3742972_8 - - - - 0.000000000000000000000000001648 114.0
WLSH2_k127_3839361_0 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 342.0
WLSH2_k127_3839361_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000003168 237.0
WLSH2_k127_3839361_2 Ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000000000000000000000000000000000001324 143.0
WLSH2_k127_3924446_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 499.0
WLSH2_k127_3924446_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 428.0
WLSH2_k127_3924446_2 CHASE3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 364.0
WLSH2_k127_3924446_3 Molybdenum ABC transporter K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 300.0
WLSH2_k127_3924446_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002257 291.0
WLSH2_k127_3924446_5 - - - - 0.00000000000000000000000000000000000000001716 155.0
WLSH2_k127_3924446_6 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000007355 170.0
WLSH2_k127_395899_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 595.0
WLSH2_k127_395899_1 lactate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000001391 204.0
WLSH2_k127_395899_2 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000003222 196.0
WLSH2_k127_3990269_0 Ammonium Transporter K03320 - - 3.485e-228 711.0
WLSH2_k127_3990269_1 Ammonium Transporter K03320 - - 4.165e-213 666.0
WLSH2_k127_3990269_2 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000000031 212.0
WLSH2_k127_3990269_3 SMART GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000002739 202.0
WLSH2_k127_3990269_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000281 169.0
WLSH2_k127_4006850_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 1.261e-225 703.0
WLSH2_k127_4006850_1 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 607.0
WLSH2_k127_4006850_2 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000000000000000009179 160.0
WLSH2_k127_4066981_0 permease K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 416.0
WLSH2_k127_4066981_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 314.0
WLSH2_k127_4066981_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 310.0
WLSH2_k127_4072515_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1155.0
WLSH2_k127_4072515_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0 1140.0
WLSH2_k127_4072515_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 366.0
WLSH2_k127_4072515_11 Chemotaxis protein cheY K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000002937 235.0
WLSH2_k127_4072515_12 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000004442 203.0
WLSH2_k127_4072515_13 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000002121 72.0
WLSH2_k127_4072515_14 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000005712 57.0
WLSH2_k127_4072515_2 COG0457 FOG TPR repeat - - - 0.0 1138.0
WLSH2_k127_4072515_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.743e-231 719.0
WLSH2_k127_4072515_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 5.484e-196 614.0
WLSH2_k127_4072515_5 acid membrane antigen A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 550.0
WLSH2_k127_4072515_6 General glycosylation pathway protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 504.0
WLSH2_k127_4072515_7 lipid a biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 469.0
WLSH2_k127_4072515_8 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 466.0
WLSH2_k127_4072515_9 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 422.0
WLSH2_k127_4078144_0 Flagellar biosynthetic protein fliR K02421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 411.0
WLSH2_k127_4078144_1 abc transporter atp-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 355.0
WLSH2_k127_4078144_2 COG1252 NADH dehydrogenase FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000001339 92.0
WLSH2_k127_4132108_0 TonB dependent receptor K02014 - - 0.0 1074.0
WLSH2_k127_4132108_1 4Fe-4S binding domain - - - 3.616e-250 778.0
WLSH2_k127_4132108_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 581.0
WLSH2_k127_4132108_3 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 300.0
WLSH2_k127_4132108_4 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001303 258.0
WLSH2_k127_4132108_5 Domain of Unknown Function (DUF350) K08989 - - 0.000000000000000000000000000000000000002394 148.0
WLSH2_k127_4164491_0 Acts as a magnesium transporter K06213 - - 1.77e-242 753.0
WLSH2_k127_4164491_1 Metallo-beta-lactamase superfamily - - - 4.403e-228 712.0
WLSH2_k127_4164491_2 Fad-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 580.0
WLSH2_k127_4164491_3 Sel1-like repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 314.0
WLSH2_k127_4164491_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000855 246.0
WLSH2_k127_4164491_5 Belongs to the UPF0312 family - - - 0.0000004084 53.0
WLSH2_k127_4174190_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 3.114e-215 674.0
WLSH2_k127_4174190_1 Arginosuccinate synthase K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 582.0
WLSH2_k127_4174190_2 Flagellar hook-length control protein FliK - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 496.0
WLSH2_k127_4174190_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000008778 214.0
WLSH2_k127_4188864_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 1.436e-209 657.0
WLSH2_k127_4188864_1 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 477.0
WLSH2_k127_4188864_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 423.0
WLSH2_k127_4188864_3 riboflavin biosynthesis protein K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 392.0
WLSH2_k127_4188864_4 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 347.0
WLSH2_k127_4188864_5 Formylmethanofuran dehydrogenase, subunit e - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 302.0
WLSH2_k127_4188864_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002414 228.0
WLSH2_k127_4188864_7 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000002904 215.0
WLSH2_k127_4226719_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 405.0
WLSH2_k127_4226719_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 395.0
WLSH2_k127_4226719_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 379.0
WLSH2_k127_4226719_3 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 374.0
WLSH2_k127_4226719_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004369 269.0
WLSH2_k127_4226719_5 - - - - 0.0000000000000000000000000000000000000000000000000000001887 195.0
WLSH2_k127_4226719_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000009715 164.0
WLSH2_k127_4240892_0 Fibronectin fibrinogen-binding protein - - - 9.186e-240 745.0
WLSH2_k127_4240892_1 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 465.0
WLSH2_k127_4240892_2 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000001963 189.0
WLSH2_k127_4240892_3 - - - - 0.000000000000000000000000000000000000004661 149.0
WLSH2_k127_4240892_4 - - - - 0.0000000000000000000000000000000002435 134.0
WLSH2_k127_4240892_5 TonB dependent receptor K16092 - - 0.0000000008966 61.0
WLSH2_k127_4244436_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 2.55e-223 694.0
WLSH2_k127_4244436_1 o-acetylhomoserine K01740 - 2.5.1.49 0.0000000000000000000000000005853 113.0
WLSH2_k127_4244436_2 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000000000000000000000006362 105.0
WLSH2_k127_4244436_3 hydrolase K01501 - 3.5.5.1 0.0001172 44.0
WLSH2_k127_425491_0 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002875 268.0
WLSH2_k127_425491_1 YaeQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000068 245.0
WLSH2_k127_425491_3 - - - - 0.00000000000000000000000000000001949 128.0
WLSH2_k127_4293552_0 Putative diguanylate phosphodiesterase - - - 3.656e-303 938.0
WLSH2_k127_4293552_1 Belongs to the CarA family K01956 - 6.3.5.5 2.741e-219 683.0
WLSH2_k127_4293552_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 458.0
WLSH2_k127_4293552_3 protein conserved in bacteria K09804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 336.0
WLSH2_k127_4293552_4 PDP protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
WLSH2_k127_4293552_5 Flagellar FliJ protein - - - 0.000000000000000000000000000000000000000000001674 168.0
WLSH2_k127_4303696_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 391.0
WLSH2_k127_4303696_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002512 267.0
WLSH2_k127_4303696_2 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000486 174.0
WLSH2_k127_4365873_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.448e-294 906.0
WLSH2_k127_4365873_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 604.0
WLSH2_k127_4365873_2 Response regulator receiver K07814 - - 0.000000000000000000000000000000000000000000000000000000008532 199.0
WLSH2_k127_4392591_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 2.861e-195 611.0
WLSH2_k127_4392591_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 402.0
WLSH2_k127_4392591_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004665 246.0
WLSH2_k127_4392591_3 Mannosyl-glycoprotein K03796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001477 249.0
WLSH2_k127_4392591_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000000000000003488 235.0
WLSH2_k127_4392591_5 - - - - 0.000000000000000000000000000000000000000000000000000000000001097 210.0
WLSH2_k127_4392591_6 ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000003728 196.0
WLSH2_k127_4392591_7 - - - - 0.000000000000000000000000000000000007434 137.0
WLSH2_k127_4392591_8 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000001704 76.0
WLSH2_k127_440548_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 4.507e-230 714.0
WLSH2_k127_440548_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000004765 243.0
WLSH2_k127_440548_2 ORF6N domain - - - 0.000000000000000000000000000000000000004625 148.0
WLSH2_k127_4483392_0 ATP-dependent CLP protease ATP-binding subunit K03694 - - 4.256e-305 940.0
WLSH2_k127_4483392_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 395.0
WLSH2_k127_4520059_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.802e-226 704.0
WLSH2_k127_4520059_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 2.106e-197 617.0
WLSH2_k127_4520059_10 NosL - - - 0.00001543 51.0
WLSH2_k127_4520059_2 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 526.0
WLSH2_k127_4520059_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 473.0
WLSH2_k127_4520059_4 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 376.0
WLSH2_k127_4520059_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 259.0
WLSH2_k127_4520059_6 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000021 203.0
WLSH2_k127_4520059_7 metal-binding, possibly nucleic acid-binding protein - - - 0.0000000000000000000000000000000000000000000000000000005433 194.0
WLSH2_k127_4520059_8 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member - - - 0.000000000000000000000000000000000000000002169 156.0
WLSH2_k127_4520059_9 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000001326 103.0
WLSH2_k127_456055_0 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 352.0
WLSH2_k127_456055_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 346.0
WLSH2_k127_456055_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000004326 169.0
WLSH2_k127_456055_3 molybdopterin converting factor K03636 - - 0.00000000000000000000000000000005135 125.0
WLSH2_k127_4564803_0 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 3.358e-238 744.0
WLSH2_k127_4564803_1 Histidine kinase K02484 - 2.7.13.3 1.255e-229 715.0
WLSH2_k127_4564803_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008401 433.0
WLSH2_k127_4564803_3 Ferredoxin K05337 - - 0.00000000000000000000000000000000000000000000000693 171.0
WLSH2_k127_4564803_4 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000002766 171.0
WLSH2_k127_4584190_0 Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 535.0
WLSH2_k127_4584190_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 338.0
WLSH2_k127_4594310_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.745e-202 631.0
WLSH2_k127_4594310_1 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 501.0
WLSH2_k127_4594310_2 PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000009565 199.0
WLSH2_k127_4596101_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2363.0
WLSH2_k127_4596101_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 - 2.7.7.6 0.0 1457.0
WLSH2_k127_4601827_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 587.0
WLSH2_k127_4601827_1 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 563.0
WLSH2_k127_4601827_2 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 417.0
WLSH2_k127_4601827_3 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002111 258.0
WLSH2_k127_4601827_4 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000007428 169.0
WLSH2_k127_4601827_5 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000000000000002622 165.0
WLSH2_k127_4601827_6 Thioredoxin-like domain - - - 0.000000009356 63.0
WLSH2_k127_4622774_0 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 504.0
WLSH2_k127_4622774_1 Belongs to the GSP D family K02453,K12282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 469.0
WLSH2_k127_4622774_3 cell adhesion K02650 - - 0.000000000000000000000002463 108.0
WLSH2_k127_4640059_0 Belongs to the HypD family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 598.0
WLSH2_k127_4640059_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 529.0
WLSH2_k127_4640059_2 Hydrogenase K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 398.0
WLSH2_k127_4640059_3 hydrogenase assembly chaperone HypC K04653 - - 0.000000000000000000000000000004441 120.0
WLSH2_k127_4730251_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 8.497e-258 795.0
WLSH2_k127_4730251_1 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 499.0
WLSH2_k127_4730251_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 449.0
WLSH2_k127_4730251_3 ABC transporter permease K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 354.0
WLSH2_k127_4730251_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 333.0
WLSH2_k127_4730251_5 PFAM ABC transporter related K02017 - 3.6.3.29 0.0000000000000000000000000000000008708 132.0
WLSH2_k127_4730251_6 molybdate ion transport - - - 0.000000000000000000000001211 108.0
WLSH2_k127_4730251_7 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000004236 63.0
WLSH2_k127_4736010_0 hydrogenase expression formation protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 532.0
WLSH2_k127_4736010_1 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000000000005489 168.0
WLSH2_k127_4736010_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000004241 83.0
WLSH2_k127_4736010_3 CHAD domain - - - 0.00006374 53.0
WLSH2_k127_4746080_0 YqaJ-like viral recombinase domain - - - 0.0000000000000000000000000000000000000000000001473 174.0
WLSH2_k127_4746080_1 dextransucrase activity - - - 0.00000000000000000000000000000000000000000000726 170.0
WLSH2_k127_4746080_2 Bacteriophage Lambda NinG protein - - - 0.000000000000000000000000000000005303 134.0
WLSH2_k127_4746080_3 Protein of unknown function (DUF1367) - - - 0.00000000000000000003109 95.0
WLSH2_k127_4746080_4 Single-stranded DNA-binding protein K03111 - - 0.0000000000000106 79.0
WLSH2_k127_4746080_5 HNH endonuclease - - - 0.000002449 57.0
WLSH2_k127_4749513_0 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 372.0
WLSH2_k127_4749513_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 312.0
WLSH2_k127_4749513_2 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001128 269.0
WLSH2_k127_4749513_3 - - - - 0.000000000000000000000000000000000000000000000000000007728 191.0
WLSH2_k127_4886915_0 arginine decarboxylase K01585 - 4.1.1.19 0.0 1173.0
WLSH2_k127_4886915_1 COGs COG0069 Glutamate synthase domain 2 - - - 6.967e-313 964.0
WLSH2_k127_4886915_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 2.451e-230 716.0
WLSH2_k127_4886915_3 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 440.0
WLSH2_k127_4886915_4 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 409.0
WLSH2_k127_4886915_5 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 383.0
WLSH2_k127_4886915_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 312.0
WLSH2_k127_4886915_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000004127 48.0
WLSH2_k127_4889774_0 The M ring may be actively involved in energy transduction K02409 - - 1.999e-291 902.0
WLSH2_k127_4889774_1 flagellar motor switch protein K02410 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 1.544e-196 615.0
WLSH2_k127_4889774_2 flagellar assembly protein FliH K02411 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 334.0
WLSH2_k127_4889774_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000008526 83.0
WLSH2_k127_4900808_0 AAA domain - - - 0.0000000000000000000000002756 115.0
WLSH2_k127_4900808_1 YqaJ-like viral recombinase domain K18173 - - 0.0000000000000000004333 94.0
WLSH2_k127_4914841_0 - - - - 0.0000000000000271 82.0
WLSH2_k127_4914841_1 nuclear chromosome segregation - - - 0.0000000000004037 76.0
WLSH2_k127_496453_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1060.0
WLSH2_k127_496453_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.694e-274 851.0
WLSH2_k127_496453_2 glucose galactose transporter K02429 - - 2.524e-202 636.0
WLSH2_k127_496453_3 of the HAD superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 426.0
WLSH2_k127_496453_4 Single-stranded-DNA-specific exonuclease (RecJ) K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000001252 235.0
WLSH2_k127_496453_5 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.000000000000001004 77.0
WLSH2_k127_496453_6 TM2 domain - - - 0.000000000000003707 84.0
WLSH2_k127_4970697_0 Aminotransferase, class I K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 374.0
WLSH2_k127_4970697_1 PFAM dUTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 369.0
WLSH2_k127_4970697_2 cofactor binding K09979 - - 0.0000000000000000000000000000000000000000000000000000000000004358 214.0
WLSH2_k127_4970697_3 ABC transporter, ATP-binding protein K02032 - - 0.00000000000000000000000000000000000000006891 152.0
WLSH2_k127_4970697_4 Uracil-DNA glycosylase - - - 0.00000000003495 65.0
WLSH2_k127_5000182_0 Archaea bacterial proteins of unknown function K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 434.0
WLSH2_k127_5000182_1 Domain of unknown function (DUF4172) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 377.0
WLSH2_k127_5000182_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000806 263.0
WLSH2_k127_5000182_3 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000002419 223.0
WLSH2_k127_500702_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0 1145.0
WLSH2_k127_500702_1 Na Pi-cotransporter K03324 - - 5.33e-295 913.0
WLSH2_k127_500702_10 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000000000000001847 217.0
WLSH2_k127_500702_11 - - - - 0.000000000000000000000000342 108.0
WLSH2_k127_500702_13 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000008282 57.0
WLSH2_k127_500702_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 9.634e-230 717.0
WLSH2_k127_500702_3 phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 552.0
WLSH2_k127_500702_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 516.0
WLSH2_k127_500702_5 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 371.0
WLSH2_k127_500702_6 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 363.0
WLSH2_k127_500702_7 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 324.0
WLSH2_k127_500702_8 PFAM Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000518 266.0
WLSH2_k127_500702_9 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000002503 267.0
WLSH2_k127_5018468_0 COGs COG3864 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 556.0
WLSH2_k127_5018468_1 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005976 248.0
WLSH2_k127_5018468_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000006929 195.0
WLSH2_k127_5039792_0 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 479.0
WLSH2_k127_5039792_1 ABC transporter permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 365.0
WLSH2_k127_5039792_2 - K21817 - 1.13.11.63 0.000000000000000000000000000000000000000000000000000003359 199.0
WLSH2_k127_5039792_3 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000001181 197.0
WLSH2_k127_5039792_5 bacteriocin export ABC transporter, lactococcin 972 group K02003 - - 0.00000000000000000000000000000001443 134.0
WLSH2_k127_5039792_6 (twin-arginine translocation) pathway signal - - - 0.000000000000002114 77.0
WLSH2_k127_5039792_7 Protein of unknown function (DUF3313) - - - 0.00002699 54.0
WLSH2_k127_5064918_0 transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 582.0
WLSH2_k127_5064918_1 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 377.0
WLSH2_k127_5064918_2 Stress responsive A B Barrel Domain - - - 0.00000000000000000000000000000000000000001752 154.0
WLSH2_k127_5064918_3 EF hand - - - 0.00000000000000000000000001508 112.0
WLSH2_k127_5064918_5 Peptidase M48 K06013 - 3.4.24.84 0.00000003669 55.0
WLSH2_k127_5122059_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 406.0
WLSH2_k127_5122059_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 358.0
WLSH2_k127_5122059_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 298.0
WLSH2_k127_5134182_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.915e-280 864.0
WLSH2_k127_5134182_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 561.0
WLSH2_k127_5134182_2 potassium channel protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 531.0
WLSH2_k127_5134182_3 diguanylate cyclase K13590,K21088 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 518.0
WLSH2_k127_5134182_4 COG0226 ABC-type phosphate transport system, periplasmic component - - - 0.00000002956 61.0
WLSH2_k127_5139509_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 611.0
WLSH2_k127_5139509_1 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 354.0
WLSH2_k127_5139509_2 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000001945 109.0
WLSH2_k127_5229872_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 1.571e-195 614.0
WLSH2_k127_5229872_1 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 422.0
WLSH2_k127_5229872_2 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 307.0
WLSH2_k127_5299698_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1410.0
WLSH2_k127_5299698_1 peptidase M23 - - - 2.608e-216 679.0
WLSH2_k127_5299698_10 riboflavin biosynthesis protein K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000003703 122.0
WLSH2_k127_5299698_11 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000004173 110.0
WLSH2_k127_5299698_12 nucleic-acid-binding protein implicated in transcription termination - - - 0.00000000000001589 76.0
WLSH2_k127_5299698_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 592.0
WLSH2_k127_5299698_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 567.0
WLSH2_k127_5299698_4 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 560.0
WLSH2_k127_5299698_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 462.0
WLSH2_k127_5299698_6 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 314.0
WLSH2_k127_5299698_7 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001207 244.0
WLSH2_k127_5299698_8 COG1214 Inactive homolog of metal-dependent proteases - - - 0.00000000000000000000000000000000000000000000000000000000000000001257 227.0
WLSH2_k127_5299698_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000000000000000000007341 205.0
WLSH2_k127_5370673_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 8.743e-247 764.0
WLSH2_k127_5370673_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.139e-242 756.0
WLSH2_k127_5370673_2 Mediates zinc uptake. May also transport other divalent cations K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 447.0
WLSH2_k127_5370673_3 RNase H - - - 0.000000000000000000000000000000000000000000000000000000000002647 212.0
WLSH2_k127_5370673_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000002075 170.0
WLSH2_k127_539626_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.211e-274 846.0
WLSH2_k127_539626_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0003674,GO:0005488,GO:0005515,GO:0042802 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 422.0
WLSH2_k127_539626_2 HAMP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 334.0
WLSH2_k127_539626_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 312.0
WLSH2_k127_539626_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009068 283.0
WLSH2_k127_539626_5 - - - - 0.000000000000000000000000000000131 136.0
WLSH2_k127_539626_6 HNH endonuclease - - - 0.0000000000000000198 89.0
WLSH2_k127_539626_7 Domain of unknown function(DUF2779) - - - 0.0000000000000003363 80.0
WLSH2_k127_5448383_0 unfolded protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 480.0
WLSH2_k127_5448383_1 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000796 212.0
WLSH2_k127_5462386_0 Outer membrane efflux protein K12543 - - 1.157e-215 676.0
WLSH2_k127_5462386_1 Belongs to the DNA mismatch repair MutS family K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 483.0
WLSH2_k127_5462386_2 Type I secretion system ATPase K12541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 465.0
WLSH2_k127_5549523_0 Inorganic pyrophosphatase K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 563.0
WLSH2_k127_5549523_1 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 442.0
WLSH2_k127_5549523_2 UPF0313 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 389.0
WLSH2_k127_5561716_0 Putative diguanylate phosphodiesterase - - - 3.22e-278 869.0
WLSH2_k127_5561716_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003198 244.0
WLSH2_k127_5561716_2 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000941 169.0
WLSH2_k127_5561716_3 PFAM TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000002828 124.0
WLSH2_k127_5561716_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000007541 71.0
WLSH2_k127_5581211_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 434.0
WLSH2_k127_5581211_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 328.0
WLSH2_k127_55836_0 Domain of Unknown Function (DUF748) - - - 0.0 1270.0
WLSH2_k127_55836_1 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 3.589e-284 876.0
WLSH2_k127_55836_2 Cytochrome c oxidase accessory protein - - - 1.064e-259 805.0
WLSH2_k127_55836_3 Belongs to the UPF0324 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 606.0
WLSH2_k127_55836_4 tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 579.0
WLSH2_k127_55836_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 288.0
WLSH2_k127_5613352_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0 1006.0
WLSH2_k127_5613352_1 Mg chelatase-related protein K07391 - - 5.979e-270 836.0
WLSH2_k127_5793075_0 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 379.0
WLSH2_k127_5793075_1 leucine binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001359 256.0
WLSH2_k127_5803523_0 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 392.0
WLSH2_k127_5803523_1 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003075 271.0
WLSH2_k127_5803523_2 GtrA-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000007185 220.0
WLSH2_k127_5803523_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000002534 213.0
WLSH2_k127_5803523_4 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000007943 48.0
WLSH2_k127_5807815_0 MMPL family K07003 - - 0.0 1067.0
WLSH2_k127_5807815_1 Glycosyl transferase - - - 2.321e-209 659.0
WLSH2_k127_5807815_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 2.7e-205 640.0
WLSH2_k127_5807815_3 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 559.0
WLSH2_k127_5807815_4 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 344.0
WLSH2_k127_5807815_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 320.0
WLSH2_k127_5807815_6 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000783 264.0
WLSH2_k127_5828943_1 Cold-shock protein K03704 - - 0.0000000000000000000000000000000000009593 140.0
WLSH2_k127_5828943_2 EAL domain - - - 0.00000000000000000000000000000004586 127.0
WLSH2_k127_5828943_3 Mut7-C RNAse domain K09122 - - 0.000000000000000001301 88.0
WLSH2_k127_5849_0 beta (1-6) glucans synthase - - - 6.566e-247 778.0
WLSH2_k127_5849_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 462.0
WLSH2_k127_5849_2 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000007749 246.0
WLSH2_k127_5849_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000003232 221.0
WLSH2_k127_5880476_0 tail specific protease K03797 - 3.4.21.102 0.000000000000000000002464 106.0
WLSH2_k127_5880476_1 Ankyrin repeats (3 copies) - - - 0.00000000003423 77.0
WLSH2_k127_5880476_2 Phospholipid glycerol acyltransferase - - - 0.000001775 51.0
WLSH2_k127_5896625_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.741e-259 807.0
WLSH2_k127_5896625_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 4.171e-210 656.0
WLSH2_k127_5896625_2 DNA methyltransferase K07318 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 419.0
WLSH2_k127_5896625_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000241 231.0
WLSH2_k127_5896625_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000000004545 185.0
WLSH2_k127_5896625_5 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000000000006412 166.0
WLSH2_k127_5924449_0 Belongs to the peptidase M16 family - - - 8.935e-259 800.0
WLSH2_k127_5924449_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 1.389e-198 621.0
WLSH2_k127_5924449_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 534.0
WLSH2_k127_5924449_3 dehydrogenase K00076 - 1.1.1.159 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 472.0
WLSH2_k127_5924449_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000006845 138.0
WLSH2_k127_5952227_0 penicillin-binding protein K05515 - 3.4.16.4 3.119e-320 984.0
WLSH2_k127_5952227_1 K -dependent Na Ca exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009189 492.0
WLSH2_k127_5952227_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000000000000001884 232.0
WLSH2_k127_5952227_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000001092 74.0
WLSH2_k127_5958853_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 9.951e-318 974.0
WLSH2_k127_5958853_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 544.0
WLSH2_k127_5958853_2 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 439.0
WLSH2_k127_5958853_3 COG3893 inactivated superfamily I helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 406.0
WLSH2_k127_5958853_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 364.0
WLSH2_k127_5958853_5 FixH - - - 0.00000000000000000000000000000000000000002063 158.0
WLSH2_k127_5958853_6 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.0000000000000000000000001398 106.0
WLSH2_k127_5958853_7 Family of unknown function (DUF4006) - - - 0.0000000000000000000001396 98.0
WLSH2_k127_5969352_0 COG2067 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 452.0
WLSH2_k127_5969352_1 - - - - 0.000000000000001626 83.0
WLSH2_k127_5996604_0 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 581.0
WLSH2_k127_5996604_1 threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 546.0
WLSH2_k127_5996604_2 Cell division protein FtsX K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 414.0
WLSH2_k127_5996604_3 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000001607 242.0
WLSH2_k127_5996604_4 - - - - 0.0000000000000000000000000000001527 128.0
WLSH2_k127_6062506_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 6.175e-274 847.0
WLSH2_k127_6062506_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 6.818e-194 608.0
WLSH2_k127_6062506_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000001038 155.0
WLSH2_k127_6098986_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 377.0
WLSH2_k127_6098986_1 COG1070 Sugar (pentulose and hexulose) K11216 - 2.7.1.189 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 348.0
WLSH2_k127_6098986_2 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000000007473 189.0
WLSH2_k127_6149760_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.513e-220 685.0
WLSH2_k127_6149760_1 Sodium/hydrogen exchanger family - - - 4.615e-194 611.0
WLSH2_k127_6149760_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 485.0
WLSH2_k127_6149760_3 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003322 265.0
WLSH2_k127_6149760_4 Phosphoesterase K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002426 241.0
WLSH2_k127_6149760_5 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000006363 153.0
WLSH2_k127_6177191_0 amino acid carrier protein K03310 - - 7.391e-259 803.0
WLSH2_k127_6177191_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 6.079e-196 618.0
WLSH2_k127_6177191_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008592 567.0
WLSH2_k127_6177191_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 488.0
WLSH2_k127_6177191_4 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 286.0
WLSH2_k127_6177191_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000003844 55.0
WLSH2_k127_6177191_8 - - - - 0.0000005859 51.0
WLSH2_k127_6177191_9 - - - - 0.0000008475 53.0
WLSH2_k127_6184914_0 Virulence protein RhuM family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 524.0
WLSH2_k127_6184914_1 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 501.0
WLSH2_k127_6184914_2 homoserine kinase type II (Protein kinase fold) K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 325.0
WLSH2_k127_6184914_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000114 238.0
WLSH2_k127_6184914_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000003944 76.0
WLSH2_k127_6184914_5 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000002525 49.0
WLSH2_k127_6213583_0 diguanylate cyclase - - - 0.0 1234.0
WLSH2_k127_6213583_1 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 1.514e-296 911.0
WLSH2_k127_6213583_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000002402 155.0
WLSH2_k127_6213716_0 COG0474 Cation transport ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 530.0
WLSH2_k127_6213716_1 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 419.0
WLSH2_k127_624678_0 - - - - 0.000000000000000000000000000000000001425 149.0
WLSH2_k127_624678_1 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000001967 147.0
WLSH2_k127_624678_2 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000002 113.0
WLSH2_k127_624678_3 Cytochrome c - - - 0.000000000000007881 83.0
WLSH2_k127_624678_4 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000001186 80.0
WLSH2_k127_624678_5 Cytochrome c - - - 0.00000000000001958 82.0
WLSH2_k127_6264749_0 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 0.0 1000.0
WLSH2_k127_6264749_1 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000000000000000000000000003098 159.0
WLSH2_k127_6264749_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000002285 82.0
WLSH2_k127_6264749_3 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000001808 70.0
WLSH2_k127_6268647_0 Protein of unknown function (DUF819) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 526.0
WLSH2_k127_6268647_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 470.0
WLSH2_k127_6268647_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 385.0
WLSH2_k127_6268647_3 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 362.0
WLSH2_k127_6268647_4 N-Acetylmuramoyl-L-alanine amidase K01207,K01447,K11066 - 3.2.1.52,3.5.1.28 0.0000000000000000000000001018 107.0
WLSH2_k127_6280897_0 Permease, YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 549.0
WLSH2_k127_6280897_1 Peptidase A24 K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 413.0
WLSH2_k127_6280897_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000181 135.0
WLSH2_k127_6284010_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 369.0
WLSH2_k127_6284010_1 SprA-related family - - - 0.000000000000000000000000000000000000000000000000000000000000000004847 231.0
WLSH2_k127_6284010_2 S4 domain K14761 - - 0.0000000000000000000000000004554 114.0
WLSH2_k127_6285484_0 GTP-binding protein K06207 - - 0.0 1151.0
WLSH2_k127_6285484_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.77e-208 649.0
WLSH2_k127_6285484_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 539.0
WLSH2_k127_6285484_3 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 377.0
WLSH2_k127_6285484_4 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000001537 199.0
WLSH2_k127_6285484_5 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.00000000000000000000008567 99.0
WLSH2_k127_6285484_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000001078 95.0
WLSH2_k127_6314251_0 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 550.0
WLSH2_k127_6314251_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 372.0
WLSH2_k127_6314251_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 339.0
WLSH2_k127_6314251_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 286.0
WLSH2_k127_633287_0 cytochrome complex assembly - - - 4.516e-320 1011.0
WLSH2_k127_633287_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000006782 63.0
WLSH2_k127_6347236_0 acetolactate synthase K01652 - 2.2.1.6 0.0 1095.0
WLSH2_k127_6347236_1 acetolactate synthase K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 286.0
WLSH2_k127_6347236_2 WD40 repeats - - - 0.000000000000000000000000001201 114.0
WLSH2_k127_6368970_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1111.0
WLSH2_k127_6368970_1 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 2.508e-246 764.0
WLSH2_k127_6368970_10 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000000000000000000000000000000000001078 161.0
WLSH2_k127_6368970_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 507.0
WLSH2_k127_6368970_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 496.0
WLSH2_k127_6368970_4 flagellar basal body K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 460.0
WLSH2_k127_6368970_5 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 454.0
WLSH2_k127_6368970_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 370.0
WLSH2_k127_6368970_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 338.0
WLSH2_k127_6368970_8 - - - - 0.000000000000000000000000000000000000000000000000000000000001535 215.0
WLSH2_k127_6368970_9 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000009487 193.0
WLSH2_k127_6378656_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.5e-323 993.0
WLSH2_k127_6378656_1 glutamine synthetase K01915 - 6.3.1.2 1.426e-306 940.0
WLSH2_k127_6378656_2 MacB-like periplasmic core domain - - - 2.15e-204 641.0
WLSH2_k127_6378656_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 560.0
WLSH2_k127_6378656_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 497.0
WLSH2_k127_6378656_5 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 368.0
WLSH2_k127_6378656_6 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 344.0
WLSH2_k127_6378656_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000003843 132.0
WLSH2_k127_6378656_8 PhoU family K02039 - - 0.000000000003702 66.0
WLSH2_k127_6389010_0 Ion transport protein K08714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 391.0
WLSH2_k127_6389010_1 Protein of unknown function (DUF3050) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 358.0
WLSH2_k127_6389010_2 - - - - 0.00000000000000000000000000000000000000000000000000000007429 197.0
WLSH2_k127_6397327_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 3.943e-231 717.0
WLSH2_k127_6397327_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 349.0
WLSH2_k127_6397327_2 - - - - 0.00000000000000000000003502 111.0
WLSH2_k127_6397327_3 - - - - 0.000001255 55.0
WLSH2_k127_6400981_0 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 1.086e-237 740.0
WLSH2_k127_6400981_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 494.0
WLSH2_k127_6400981_2 Transport permease protein K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 429.0
WLSH2_k127_6425890_0 DUF218 domain - - - 0.000000000000000000000000000000000000000000000001921 176.0
WLSH2_k127_6425890_1 COG0642 Signal transduction histidine kinase K20971 - - 0.000000000000000000000006692 113.0
WLSH2_k127_6427612_0 N-4 methylation of cytosine K03497,K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 421.0
WLSH2_k127_6427612_1 Terminase-like family - - - 0.00000000000000000000000000000000000000000000006384 178.0
WLSH2_k127_6434170_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001299 269.0
WLSH2_k127_6434170_1 Hemolysin K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000001077 133.0
WLSH2_k127_6434170_2 - - - - 0.000000000000007306 78.0
WLSH2_k127_6564331_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 389.0
WLSH2_k127_6564331_1 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000001648 216.0
WLSH2_k127_6565868_0 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 1.171e-245 764.0
WLSH2_k127_6565868_1 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 497.0
WLSH2_k127_6565868_2 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 355.0
WLSH2_k127_6565868_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 332.0
WLSH2_k127_6565868_4 diguanylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001596 284.0
WLSH2_k127_6565868_5 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007429 261.0
WLSH2_k127_6565868_6 - - - - 0.0000000000000000000000000000000000000000000003309 168.0
WLSH2_k127_6565868_7 of the cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000000000000000000000006513 140.0
WLSH2_k127_6565868_9 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000001051 101.0
WLSH2_k127_6634365_0 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 564.0
WLSH2_k127_6634365_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 344.0
WLSH2_k127_6634365_2 - - - - 0.000000000000000000000000000000000000000003043 155.0
WLSH2_k127_6647659_0 peptidylprolyl isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 441.0
WLSH2_k127_6647659_1 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 361.0
WLSH2_k127_6647659_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000008505 232.0
WLSH2_k127_6655090_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.024e-320 986.0
WLSH2_k127_6655090_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 513.0
WLSH2_k127_6655090_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 368.0
WLSH2_k127_6655090_4 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000001879 111.0
WLSH2_k127_6670870_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 488.0
WLSH2_k127_6670870_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000001128 242.0
WLSH2_k127_6670870_2 beta-lactamase K17838 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000001203 211.0
WLSH2_k127_6670870_3 Heavy-metal-associated domain - - - 0.000000000000000000000000000000000000001045 150.0
WLSH2_k127_6699668_0 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 441.0
WLSH2_k127_6699668_1 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 338.0
WLSH2_k127_6699668_2 Abc transporter K09816 - - 0.00000000002664 64.0
WLSH2_k127_6709771_0 transporter - - - 5.547e-239 743.0
WLSH2_k127_6709771_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000001223 159.0
WLSH2_k127_6724121_0 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 1.705e-196 615.0
WLSH2_k127_6724121_1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 593.0
WLSH2_k127_6724121_2 phage repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 381.0
WLSH2_k127_6724121_3 Flagellar hook protein flgE - - - 0.00000000000000000000000000000000000002024 145.0
WLSH2_k127_6736855_0 molybdopterin oxidoreductase - - - 2.967e-313 965.0
WLSH2_k127_6736855_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 1.269e-240 745.0
WLSH2_k127_6736855_10 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004042 273.0
WLSH2_k127_6736855_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008013 256.0
WLSH2_k127_6736855_12 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003789 246.0
WLSH2_k127_6736855_13 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001241 246.0
WLSH2_k127_6736855_14 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000001377 157.0
WLSH2_k127_6736855_15 PFAM secretion protein HlyD family protein - - - 0.00000000000000000000000000000000000005095 153.0
WLSH2_k127_6736855_2 twitching motility protein K02669 - - 6.627e-200 627.0
WLSH2_k127_6736855_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 565.0
WLSH2_k127_6736855_4 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 459.0
WLSH2_k127_6736855_5 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 443.0
WLSH2_k127_6736855_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 449.0
WLSH2_k127_6736855_7 Response regulator receiver K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 399.0
WLSH2_k127_6736855_8 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 400.0
WLSH2_k127_6736855_9 Signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 394.0
WLSH2_k127_6765689_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 1.124e-212 662.0
WLSH2_k127_6765689_1 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 573.0
WLSH2_k127_6765689_2 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 304.0
WLSH2_k127_6765689_3 Membrane protease subunits - - - 0.0000000000000000000000000000000000000003352 150.0
WLSH2_k127_6784023_0 molybdopterin biosynthesis K03750 - 2.10.1.1 5.283e-201 629.0
WLSH2_k127_6784023_1 ATPase (AAA K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 593.0
WLSH2_k127_6784023_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 533.0
WLSH2_k127_6784023_3 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 377.0
WLSH2_k127_6784023_4 ribosomal protein L3 K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 362.0
WLSH2_k127_6784023_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 299.0
WLSH2_k127_6784023_6 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000000001931 198.0
WLSH2_k127_6784023_7 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000000000000000001381 185.0
WLSH2_k127_6845176_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 453.0
WLSH2_k127_6845176_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 324.0
WLSH2_k127_6845176_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 293.0
WLSH2_k127_6845176_4 YGGT family K02221 - - 0.000000000000000000000000000000000000004508 147.0
WLSH2_k127_685215_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 1.525e-302 931.0
WLSH2_k127_685215_1 Belongs to the Fur family K03711 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 308.0
WLSH2_k127_685215_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 0.000000000000000001932 85.0
WLSH2_k127_6860712_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0 1187.0
WLSH2_k127_6860712_1 WD40 repeats - - - 5.812e-295 920.0
WLSH2_k127_6860712_2 ATP synthase K02412 - 3.6.3.14 4.589e-238 740.0
WLSH2_k127_6860712_3 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 354.0
WLSH2_k127_6919026_0 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 3.9e-206 645.0
WLSH2_k127_6919026_1 COGs COG0665 Glycine D-amino acid oxidase (deaminating) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 541.0
WLSH2_k127_6919026_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 531.0
WLSH2_k127_6919026_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 445.0
WLSH2_k127_6919026_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 442.0
WLSH2_k127_6919026_5 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000003459 204.0
WLSH2_k127_6943416_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1334.0
WLSH2_k127_6943416_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 391.0
WLSH2_k127_6943416_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000001382 177.0
WLSH2_k127_6943416_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000001654 64.0
WLSH2_k127_6943416_5 - - - - 0.000002332 52.0
WLSH2_k127_6960565_0 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 2.484e-210 660.0
WLSH2_k127_6960565_1 Cysteine desulfurase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 477.0
WLSH2_k127_6960565_2 cofactor biosynthesis protein NifE K02587 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 456.0
WLSH2_k127_6960565_3 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 438.0
WLSH2_k127_6960565_4 NifQ K15790 - - 0.0000000000000000000000000000000000000000001011 162.0
WLSH2_k127_6960565_5 Dinitrogenase iron-molybdenum cofactor K02596 - - 0.0000000000000000000000000000000000000000001657 161.0
WLSH2_k127_6960565_6 nitrogen fixation - - - 0.00000000000000000000000000007382 122.0
WLSH2_k127_7057051_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 4.431e-236 739.0
WLSH2_k127_7061917_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1228.0
WLSH2_k127_7061917_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 1.768e-227 715.0
WLSH2_k127_7061917_2 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 533.0
WLSH2_k127_7061917_3 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 459.0
WLSH2_k127_7061917_4 general secretion pathway protein K02247,K02456,K02679,K12285 - - 0.0000000000000000000000000000000000000000000000000000000000000000002978 235.0
WLSH2_k127_7061917_5 Prokaryotic N-terminal methylation motif K12285 - - 0.00000000000000000000000000000001705 132.0
WLSH2_k127_7061917_6 cell adhesion K02650 - - 0.0000000000000000000082 100.0
WLSH2_k127_7061917_7 Type II secretion system (T2SS), protein F K02653 - - 0.000004452 58.0
WLSH2_k127_7064985_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1108.0
WLSH2_k127_7064985_1 Ferritin K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 314.0
WLSH2_k127_7073764_0 Sulfatase - - - 0.0 1024.0
WLSH2_k127_7073764_1 PFAM HI0933 family protein K07007 - - 3.02e-207 649.0
WLSH2_k127_7073764_2 Protein of unknown function (DUF3137) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 456.0
WLSH2_k127_7073764_3 Etoposide-induced protein 2.4 (EI24) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 359.0
WLSH2_k127_7073764_4 Outer membrane protein beta-barrel family K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 319.0
WLSH2_k127_7073764_5 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 285.0
WLSH2_k127_7073764_6 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000000001586 184.0
WLSH2_k127_7073764_7 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000000000000000000001091 153.0
WLSH2_k127_7073764_8 cytochrome K08738 - - 0.000000000000000000000000000000000002812 143.0
WLSH2_k127_7073764_9 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 0.000000000000000000000001941 102.0
WLSH2_k127_7085459_0 Histidine kinase - - - 5.272e-209 654.0
WLSH2_k127_7085459_1 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006490,GO:0006629,GO:0008150,GO:0008152,GO:0008960,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0042597,GO:0044237,GO:0044238,GO:0044255,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576 2.7.8.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 461.0
WLSH2_k127_7085459_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 290.0
WLSH2_k127_7085459_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000006292 217.0
WLSH2_k127_7085459_4 COG0155 Sulfite reductase, beta subunit (hemoprotein) K00366 - 1.7.7.1 0.000000000000000000003197 92.0
WLSH2_k127_7096128_0 abc transporter atp-binding protein - - - 0.0 1027.0
WLSH2_k127_7096128_1 Malate quinone- oxidoreductase K00116 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.5.4 1.359e-291 898.0
WLSH2_k127_7096128_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006625 276.0
WLSH2_k127_7096128_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001408 231.0
WLSH2_k127_7096128_4 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000000000000000000000000008836 185.0
WLSH2_k127_7096128_5 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000000000000009773 153.0
WLSH2_k127_7096128_6 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.3,1.4.1.4 0.00000000004067 64.0
WLSH2_k127_7129047_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 3.744e-305 953.0
WLSH2_k127_7129047_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.321e-257 794.0
WLSH2_k127_7129047_10 Flagellar biosynthetic protein FliQ K02420 - - 0.00000000000000000000000000000000000000001032 154.0
WLSH2_k127_7129047_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000006565 152.0
WLSH2_k127_7129047_2 Cysteine desulfurase K04487 - 2.8.1.7 2.121e-241 748.0
WLSH2_k127_7129047_3 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 1.159e-196 614.0
WLSH2_k127_7129047_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 520.0
WLSH2_k127_7129047_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 518.0
WLSH2_k127_7129047_6 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 482.0
WLSH2_k127_7129047_7 cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 449.0
WLSH2_k127_7129047_8 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 355.0
WLSH2_k127_7129047_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006056 249.0
WLSH2_k127_7144473_0 Peptidase, M16 - - - 5.285e-195 615.0
WLSH2_k127_7144473_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 309.0
WLSH2_k127_7144473_2 ATP-dependent DNA helicase K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000001489 240.0
WLSH2_k127_7177942_0 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 301.0
WLSH2_k127_7177942_1 iron-sulfur transferase activity K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 294.0
WLSH2_k127_7177942_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003254 272.0
WLSH2_k127_7177942_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000001774 218.0
WLSH2_k127_7177942_4 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000001211 166.0
WLSH2_k127_7177942_6 COG1393 Arsenate reductase and related K00537 - 1.20.4.1 0.00000000000000000000000000000000000000008391 153.0
WLSH2_k127_7177942_7 Predicted membrane protein (DUF2061) - - - 0.0000000000000000000000000000000001285 133.0
WLSH2_k127_7177942_8 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000006603 122.0
WLSH2_k127_7190327_0 Protein of unknown function (DUF2867) - - - 3.051e-228 711.0
WLSH2_k127_7190327_1 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000148 131.0
WLSH2_k127_7215814_0 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 510.0
WLSH2_k127_7215814_1 Protein of unknown function (DUF3015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005886 259.0
WLSH2_k127_7215814_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000001939 137.0
WLSH2_k127_7240723_0 nitrite reductase K15864 - 1.7.2.1,1.7.99.1 0.0 1062.0
WLSH2_k127_7240723_1 Heme d1 biosynthesis protein NirJ - - - 3.013e-227 705.0
WLSH2_k127_7240723_2 Heme d1 biosynthesis protein NirF K19345 - - 1.321e-212 663.0
WLSH2_k127_7240723_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02303,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 460.0
WLSH2_k127_7240723_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 323.0
WLSH2_k127_7240723_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000004515 162.0
WLSH2_k127_7240723_6 Nitric oxide reductase K04561 - 1.7.2.5 0.0000000000000000000000000000000000716 134.0
WLSH2_k127_7240723_7 - - - - 0.00000000000000000001253 91.0
WLSH2_k127_7247162_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1666.0
WLSH2_k127_7247162_1 DNA helicase K03657 - 3.6.4.12 0.0 1031.0
WLSH2_k127_7247162_10 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000002906 70.0
WLSH2_k127_7247162_2 Sulfate permease K03321 - - 9.27e-287 887.0
WLSH2_k127_7247162_3 COG0659 Sulfate permease and related K03321 - - 9.18e-277 856.0
WLSH2_k127_7247162_4 cyclic-guanylate-specific phosphodiesterase activity - - - 1.54e-197 621.0
WLSH2_k127_7247162_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 599.0
WLSH2_k127_7247162_6 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000005579 255.0
WLSH2_k127_7247162_7 GatB Yqey family protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000000000000216 228.0
WLSH2_k127_7247162_9 COG1734 DnaK suppressor protein K06204 - - 0.00000000000000000000000000000003709 128.0
WLSH2_k127_7257666_0 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 582.0
WLSH2_k127_7257666_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 387.0
WLSH2_k127_7257666_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 324.0
WLSH2_k127_7257666_3 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000007616 226.0
WLSH2_k127_7257666_4 carbonic anhydrase K01674 - 4.2.1.1 0.000000000000000000001783 93.0
WLSH2_k127_7277676_0 na -driven multidrug efflux - - - 2.846e-220 690.0
WLSH2_k127_7277676_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 482.0
WLSH2_k127_7277676_2 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001243 274.0
WLSH2_k127_7277676_3 - - - - 0.000000000000000000000000000000000002363 139.0
WLSH2_k127_7277676_4 NnrS protein K07234 - - 0.00000003677 55.0
WLSH2_k127_7322824_0 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 565.0
WLSH2_k127_7322824_1 Belongs to the TtcA family K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 438.0
WLSH2_k127_7322824_2 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K18284 - 3.2.2.30,3.2.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 405.0
WLSH2_k127_7322824_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 362.0
WLSH2_k127_7322824_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 327.0
WLSH2_k127_7322824_5 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 298.0
WLSH2_k127_7322824_6 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 282.0
WLSH2_k127_7322824_7 - - - - 0.0000000000000000000000000000000000000000000000000000000002747 206.0
WLSH2_k127_7322824_8 repeat protein - - - 0.00000000000000000000000000000000000000009687 151.0
WLSH2_k127_7376808_0 DnaJ domain protein K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 405.0
WLSH2_k127_7376808_2 phosphoribosyltransferase K00769 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000004377 231.0
WLSH2_k127_7428134_0 Glycosyltransferase (GlcNAc) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 358.0
WLSH2_k127_7428134_1 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000000003445 228.0
WLSH2_k127_7428134_2 Cobalamin biosynthesis protein CobT VWA domain K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000007348 144.0
WLSH2_k127_7453834_0 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 352.0
WLSH2_k127_7453834_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000005495 195.0
WLSH2_k127_7456686_0 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 434.0
WLSH2_k127_7456686_1 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000006425 133.0
WLSH2_k127_7456686_2 Cytochrome c K08738 - - 0.00000000000000000000000387 105.0
WLSH2_k127_7463169_0 Flagellar Assembly Protein A - - - 9.65e-316 977.0
WLSH2_k127_7463169_1 Mur ligase middle domain K01929 - 6.3.2.10 3.299e-270 835.0
WLSH2_k127_7463169_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 575.0
WLSH2_k127_7463169_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 421.0
WLSH2_k127_7463169_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 302.0
WLSH2_k127_7463169_5 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000001179 219.0
WLSH2_k127_7463169_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000172 70.0
WLSH2_k127_7491298_0 Aminotransferase - - - 1.228e-231 722.0
WLSH2_k127_7491298_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 561.0
WLSH2_k127_7491298_2 Sulfite reductase beta subunit (hemoprotein) K00392 - 1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 506.0
WLSH2_k127_7491298_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 441.0
WLSH2_k127_7491298_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 384.0
WLSH2_k127_7491298_5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 331.0
WLSH2_k127_7496356_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 452.0
WLSH2_k127_7496356_1 Signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 452.0
WLSH2_k127_7496356_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 291.0
WLSH2_k127_7496356_3 - - - - 0.000000000000000000000000000000000000000000000000002749 184.0
WLSH2_k127_7496356_4 Ribonuclease K12573 - - 0.0000000000000000000000000000000000000000000004327 168.0
WLSH2_k127_7497481_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 3.69e-221 687.0
WLSH2_k127_7497481_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 330.0
WLSH2_k127_7497481_2 - - - - 0.00000000000000000000000000000000000000000764 156.0
WLSH2_k127_7497481_3 Belongs to the flagella basal body rod proteins family K02392 - - 0.000000000000000000000000000000001248 129.0
WLSH2_k127_7497481_4 - - - - 0.0000000000000000000003252 98.0
WLSH2_k127_7517611_0 o-acetylhomoserine K01740 - 2.5.1.49 3.177e-224 698.0
WLSH2_k127_7517611_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 404.0
WLSH2_k127_7517611_2 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 291.0
WLSH2_k127_7517611_3 - - - - 0.00000000000000000000000000000000000000000000000000000002657 198.0
WLSH2_k127_7517611_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000002422 125.0
WLSH2_k127_7576951_0 diguanylate cyclase - - - 0.0 1001.0
WLSH2_k127_7576951_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 3.73e-293 900.0
WLSH2_k127_7576951_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.692e-253 785.0
WLSH2_k127_7576951_3 sulfate adenylyltransferase K00958 - 2.7.7.4 1.371e-224 700.0
WLSH2_k127_7576951_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 6.56e-217 675.0
WLSH2_k127_7576951_5 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 8.179e-203 636.0
WLSH2_k127_7576951_6 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 302.0
WLSH2_k127_7576951_7 response regulator - - - 0.00000000000000000000000000000000000001992 155.0
WLSH2_k127_7576951_8 - - - - 0.00000000000000007891 80.0
WLSH2_k127_7591887_0 Hpt sensor hybrid histidine kinase - - - 1.606e-311 964.0
WLSH2_k127_7591887_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 486.0
WLSH2_k127_7591887_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 397.0
WLSH2_k127_7591887_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 348.0
WLSH2_k127_7595635_0 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 353.0
WLSH2_k127_7595635_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 310.0
WLSH2_k127_7595635_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002609 237.0
WLSH2_k127_7596005_0 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0 1011.0
WLSH2_k127_7596005_1 cAMP phosphodiesterases class-II - - - 3.6e-291 905.0
WLSH2_k127_7596005_2 PFAM FecR protein - - - 0.000000000000000000000000000000000001307 141.0
WLSH2_k127_7596005_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000004343 108.0
WLSH2_k127_7596005_4 - - - - 0.000000146 55.0
WLSH2_k127_7606151_0 helicase superfamily c-terminal domain K19789 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 323.0
WLSH2_k127_7639956_0 PFAM EAL domain - - - 9.169e-241 760.0
WLSH2_k127_7639956_1 Belongs to the ALAD family K01698 - 4.2.1.24 1.313e-195 611.0
WLSH2_k127_7639956_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 546.0
WLSH2_k127_7639956_3 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 497.0
WLSH2_k127_7639956_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 487.0
WLSH2_k127_7639956_5 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 335.0
WLSH2_k127_7639956_6 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 324.0
WLSH2_k127_7639956_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000009405 243.0
WLSH2_k127_7639956_8 - - - - 0.000000000000000000000000000000000000000000000000000001969 194.0
WLSH2_k127_7639956_9 - - - - 0.0000000000000000000000000000000000000005832 154.0
WLSH2_k127_7674484_0 threonine synthase K01733 - 4.2.3.1 2.634e-244 757.0
WLSH2_k127_7674484_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 392.0
WLSH2_k127_7729160_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 512.0
WLSH2_k127_7729160_1 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 477.0
WLSH2_k127_7729160_2 Fibronectin type 3 domain-containing protein K06882 - - 0.000000000000000000000000000000000000000000000000000000000000000002175 230.0
WLSH2_k127_7787_0 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007886 493.0
WLSH2_k127_7787_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 368.0
WLSH2_k127_7787_2 - - - - 0.000000000000000000000000000007511 120.0
WLSH2_k127_7885156_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.274e-315 970.0
WLSH2_k127_7885156_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000126 278.0
WLSH2_k127_7885156_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006534 241.0
WLSH2_k127_7885156_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000003306 147.0
WLSH2_k127_7889438_0 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 522.0
WLSH2_k127_7889438_1 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 457.0
WLSH2_k127_7889438_2 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.00000000006576 63.0
WLSH2_k127_7906935_0 Mechanosensitive ion channel - - - 3.844e-220 691.0
WLSH2_k127_7906935_1 M42 glutamyl aminopeptidase - - - 1.705e-196 615.0
WLSH2_k127_7906935_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000004561 209.0
WLSH2_k127_7906935_11 - - - - 0.0000000000000000000000000000000000002842 141.0
WLSH2_k127_7906935_12 - - - - 0.000000000000000000000000000000001206 130.0
WLSH2_k127_7906935_15 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000003538 66.0
WLSH2_k127_7906935_2 Belongs to the RimK family K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 549.0
WLSH2_k127_7906935_3 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 472.0
WLSH2_k127_7906935_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 438.0
WLSH2_k127_7906935_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 423.0
WLSH2_k127_7906935_6 CorA-like Mg2 transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 371.0
WLSH2_k127_7906935_7 Prolyl 4-hydroxylase alpha subunit homologues. K07394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000476 271.0
WLSH2_k127_7906935_8 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003296 246.0
WLSH2_k127_7906935_9 Histidine kinase K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001381 220.0
WLSH2_k127_7920302_0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.0 1009.0
WLSH2_k127_7920302_1 Chaperone for flagella basal body P-ring formation K02386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 355.0
WLSH2_k127_7920302_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 311.0
WLSH2_k127_7920302_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000591 271.0
WLSH2_k127_7920302_4 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.000003989 49.0
WLSH2_k127_7938586_0 Transglycosylase SLT domain K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 527.0
WLSH2_k127_7938586_1 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 405.0
WLSH2_k127_7938586_2 - - - - 0.000000000000000000000000000000745 123.0
WLSH2_k127_7954151_0 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 8.581e-217 682.0
WLSH2_k127_7954151_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 512.0
WLSH2_k127_7954151_2 component I K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 362.0
WLSH2_k127_7954151_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 349.0
WLSH2_k127_7954151_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001012 231.0
WLSH2_k127_7956812_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.081e-249 775.0
WLSH2_k127_7956812_1 peptidylprolyl isomerase K03770 - 5.2.1.8 1.426e-213 673.0
WLSH2_k127_7956812_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 5.715e-210 655.0
WLSH2_k127_7956812_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.31e-203 636.0
WLSH2_k127_7956812_5 - - - - 0.0000000000000000000000000000000000000000000001742 170.0
WLSH2_k127_7956812_6 outer membrane porin, OprD family - - - 0.0000000000000000004338 87.0
WLSH2_k127_7961906_0 Phage-related minor tail protein - - - 0.0000000000000000000000004191 123.0
WLSH2_k127_7961906_1 Phage head-tail joining protein - - - 0.000000000000000001114 89.0
WLSH2_k127_7961906_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000371 83.0
WLSH2_k127_7961906_3 Bacteriophage HK97-gp10, putative tail-component - - - 0.00000000000008479 76.0
WLSH2_k127_7961906_4 Protein of unknown function (DUF3168) - - - 0.0000002829 57.0
WLSH2_k127_7961906_5 Phage gp6-like head-tail connector protein - - - 0.00002938 53.0
WLSH2_k127_8000423_0 Major Facilitator Superfamily K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 555.0
WLSH2_k127_8000423_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 331.0
WLSH2_k127_8000423_2 alanine dehydrogenase K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000007847 243.0
WLSH2_k127_8000423_3 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000005602 155.0
WLSH2_k127_8009190_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.673e-233 725.0
WLSH2_k127_8009190_1 HAD-superfamily hydrolase, subfamily IIA K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 430.0
WLSH2_k127_8009190_2 permease K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001326 244.0
WLSH2_k127_8009190_3 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000003346 171.0
WLSH2_k127_803266_0 Abc transporter K06158 - - 3.046e-316 974.0
WLSH2_k127_803266_1 Diguanylate cyclase K21021 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 385.0
WLSH2_k127_803266_2 diguanylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000002532 189.0
WLSH2_k127_8034362_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 554.0
WLSH2_k127_8034362_1 COG4886 Leucine-rich repeat (LRR) protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 407.0
WLSH2_k127_8034362_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 342.0
WLSH2_k127_8034362_3 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000003991 220.0
WLSH2_k127_8034362_4 Nitrogenase cofactor biosynthesis protein NifB K02585 - - 0.000000000000000000000000000000000000000000000000001888 184.0
WLSH2_k127_8034362_5 - - - - 0.00000000000000000000000000000001105 128.0
WLSH2_k127_8040719_0 Belongs to the AAA ATPase family - - - 2.376e-281 871.0
WLSH2_k127_8040719_1 mechanosensitive ion channel - - - 7.224e-271 841.0
WLSH2_k127_8040719_2 MiaB-like tRNA modifying enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 536.0
WLSH2_k127_8040719_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 372.0
WLSH2_k127_8053395_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 9.931e-254 786.0
WLSH2_k127_8053395_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 337.0
WLSH2_k127_8053395_2 Binds to the 23S rRNA K02939 - - 0.0000000000002744 69.0
WLSH2_k127_8069760_0 ABC transporter, ATP-binding protein K15738 - - 2.775e-314 965.0
WLSH2_k127_8069760_1 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 7.858e-252 781.0
WLSH2_k127_8069760_2 Molecular chaperone. Has ATPase activity K04079 - - 5.184e-229 712.0
WLSH2_k127_8069760_3 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 346.0
WLSH2_k127_8145234_0 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000002297 214.0
WLSH2_k127_8145234_1 Sporulation related domain - - - 0.000000000000000000000000005842 126.0
WLSH2_k127_8145234_2 amine dehydrogenase activity - - - 0.000000000000000009299 84.0
WLSH2_k127_8153712_0 3-deoxy-d-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 4.443e-200 628.0
WLSH2_k127_8153712_1 dinuclear metal center protein, YbgI K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 441.0
WLSH2_k127_8153712_2 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 412.0
WLSH2_k127_8153712_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001703 269.0
WLSH2_k127_8153712_4 peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000009983 228.0
WLSH2_k127_8153712_5 Belongs to the pseudouridine synthase RluA family K06179,K06180 - 5.4.99.23,5.4.99.24 0.00000000000000000000000000000000000000000000000000001884 188.0
WLSH2_k127_8166816_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 399.0
WLSH2_k127_8166816_1 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 303.0
WLSH2_k127_8166816_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000001001 94.0
WLSH2_k127_8166816_3 Ankyrin repeat K06867,K21440 - - 0.000000000004225 72.0
WLSH2_k127_8177905_0 flagellar biosynthesis K02404 - - 1.346e-202 636.0
WLSH2_k127_8177905_1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003217 258.0
WLSH2_k127_8177905_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000001319 248.0
WLSH2_k127_8264803_0 EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009559 598.0
WLSH2_k127_8264803_1 McrBC 5-methylcytosine restriction system component K19147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 555.0
WLSH2_k127_8264803_2 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 493.0
WLSH2_k127_8264803_3 AAA domain (dynein-related subfamily) K07452 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 334.0
WLSH2_k127_8264803_4 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003325 245.0
WLSH2_k127_8279_0 NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 319.0
WLSH2_k127_8293462_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 561.0
WLSH2_k127_8293462_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 548.0
WLSH2_k127_8293462_10 PFAM PAS fold-3 domain protein K03776 - - 0.0000000000000000000000000000000000000001292 150.0
WLSH2_k127_8293462_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000116 110.0
WLSH2_k127_8293462_2 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 511.0
WLSH2_k127_8293462_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 469.0
WLSH2_k127_8293462_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 454.0
WLSH2_k127_8293462_5 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 452.0
WLSH2_k127_8293462_6 DNA processing protein K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 370.0
WLSH2_k127_8293462_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001071 271.0
WLSH2_k127_8293462_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001709 248.0
WLSH2_k127_8293462_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000000001329 174.0
WLSH2_k127_829415_0 wide pore channel activity K07267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 345.0
WLSH2_k127_829415_1 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000000002612 134.0
WLSH2_k127_829415_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000618 89.0
WLSH2_k127_8317336_0 Terminase RNaseH-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 292.0
WLSH2_k127_8317336_1 Domain of unknown function (DUF4055) - - - 0.00000000000000000000000000000000000000000000000000000000000009734 229.0
WLSH2_k127_8317336_2 Phage Mu protein F like protein - - - 0.000000000000000000000000000000000000000000000976 178.0
WLSH2_k127_8317336_3 - - - - 0.0000000000000001352 90.0
WLSH2_k127_8317336_4 - - - - 0.0000000001333 68.0
WLSH2_k127_8317336_5 - - - - 0.00000008327 61.0
WLSH2_k127_8342888_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1493.0
WLSH2_k127_8342888_1 Diguanylate cyclase - - - 1.57e-257 801.0
WLSH2_k127_8342888_2 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 530.0
WLSH2_k127_8342888_3 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000001018 238.0
WLSH2_k127_8342888_4 Lipopolysaccharide-assembly - - - 0.00000000000000000000000000000000000000000000000000000000000002482 216.0
WLSH2_k127_8342888_5 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000000001107 172.0
WLSH2_k127_8344664_0 Ribonuclease K12573 - - 0.0 1001.0
WLSH2_k127_8344664_1 DNA polymerase III K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 524.0
WLSH2_k127_8344664_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000002163 232.0
WLSH2_k127_8344664_3 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000008767 202.0
WLSH2_k127_8346640_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 361.0
WLSH2_k127_8346640_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 284.0
WLSH2_k127_8346640_2 - - - - 0.000000000000000000000000000000000000000000000000000000000008266 207.0
WLSH2_k127_8391313_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 4.484e-217 677.0
WLSH2_k127_8391313_1 Jag_N K06346 - - 0.0000001254 61.0
WLSH2_k127_8409831_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 6.792e-199 623.0
WLSH2_k127_8409831_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 486.0
WLSH2_k127_8409831_2 COG1252 NADH dehydrogenase FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000171 256.0
WLSH2_k127_8409831_3 Protein of unknown function (DUF3373) - - - 0.00000000003332 68.0
WLSH2_k127_8463686_0 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 536.0
WLSH2_k127_8463686_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 434.0
WLSH2_k127_8463686_2 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 311.0
WLSH2_k127_8463686_3 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0000000003577 60.0
WLSH2_k127_8471964_0 Major facilitator superfamily K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 378.0
WLSH2_k127_8471964_1 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000008536 226.0
WLSH2_k127_848821_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 1.752e-224 713.0
WLSH2_k127_848821_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 4.311e-194 606.0
WLSH2_k127_848821_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 535.0
WLSH2_k127_848821_3 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 392.0
WLSH2_k127_848821_4 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 341.0
WLSH2_k127_848821_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 332.0
WLSH2_k127_8489525_0 chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 529.0
WLSH2_k127_8489525_1 Major facilitator superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 300.0
WLSH2_k127_8489525_2 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007732 271.0
WLSH2_k127_8489525_3 Telomere recombination K04656 - - 0.000000000000000000000000000000000000000002609 158.0
WLSH2_k127_8489525_4 PAS fold K03776 - - 0.0000000000000000000000000000000000001301 147.0
WLSH2_k127_8489525_5 chemotaxis protein - - - 0.000000000000003877 79.0
WLSH2_k127_8529863_0 COG0642 Signal transduction histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 450.0
WLSH2_k127_8529863_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000002078 137.0
WLSH2_k127_8533248_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 561.0
WLSH2_k127_8533248_1 TIGRFAM cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 307.0
WLSH2_k127_8533248_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000688 94.0
WLSH2_k127_8625814_0 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 8.71e-234 725.0
WLSH2_k127_8625814_1 chemotaxis protein K03406 - - 3.185e-220 694.0
WLSH2_k127_8625814_2 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 380.0
WLSH2_k127_8625814_3 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009436 329.0
WLSH2_k127_8625814_4 Signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000001755 216.0
WLSH2_k127_8625814_5 Dihaem cytochrome c - - - 0.000000000000000000000000000000000000000000000000001589 187.0
WLSH2_k127_8625814_6 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000112 175.0
WLSH2_k127_8625814_7 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000000000000003896 158.0
WLSH2_k127_8626112_0 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 2.548e-198 624.0
WLSH2_k127_8626112_1 Fibronectin type 3 domain-containing protein K06882 - - 0.0000000000000000000000000000000000000000000000000000005577 196.0
WLSH2_k127_8659529_0 Glutathionylspermidine synthase - - - 1.6e-227 708.0
WLSH2_k127_8659529_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002155 251.0
WLSH2_k127_8659529_2 - - - - 0.000000000000000000000000000000000000000000000000001243 186.0
WLSH2_k127_8659529_3 Polysaccharide biosynthesis protein K15912 - 4.2.1.135 0.00000000000000000002644 90.0
WLSH2_k127_867701_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 2142.0
WLSH2_k127_867701_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 512.0
WLSH2_k127_867701_2 4Fe-4S ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 446.0
WLSH2_k127_867701_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 366.0
WLSH2_k127_867701_4 phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000052 235.0
WLSH2_k127_867701_5 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000003033 223.0
WLSH2_k127_867701_6 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000006464 205.0
WLSH2_k127_867701_7 Membrane - - - 0.00000000000000000000000000000000000000000000005835 173.0
WLSH2_k127_8701123_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 6.462e-195 610.0
WLSH2_k127_8701123_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 351.0
WLSH2_k127_8701123_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000003978 189.0
WLSH2_k127_8701123_3 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000004608 159.0
WLSH2_k127_8701123_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000002985 152.0
WLSH2_k127_8750285_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 1.893e-217 676.0
WLSH2_k127_8750285_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 490.0
WLSH2_k127_8750285_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000005963 201.0
WLSH2_k127_8750285_3 - - - - 0.000000000000000000000000000000000000000000876 159.0
WLSH2_k127_8750285_4 - - - - 0.000000000000000000001171 97.0
WLSH2_k127_8757158_0 pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 1.307e-271 841.0
WLSH2_k127_8757158_1 Single-stranded-DNA-specific exonuclease (RecJ) K07462 - - 2.76e-256 799.0
WLSH2_k127_8757158_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000009188 204.0
WLSH2_k127_8757158_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000004637 79.0
WLSH2_k127_8772106_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.141e-247 766.0
WLSH2_k127_8772106_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.367e-238 742.0
WLSH2_k127_8772106_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 477.0
WLSH2_k127_8772106_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 449.0
WLSH2_k127_8772106_4 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 384.0
WLSH2_k127_8772106_5 FxsA cytoplasmic membrane protein K01649,K07113 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000004945 216.0
WLSH2_k127_8772106_7 Domain of unknown function (DUF2018) - - - 0.0000000000000000000000000000000000001152 143.0
WLSH2_k127_8833406_0 Haem-binding uptake, Tiki superfamily, ChaN K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 384.0
WLSH2_k127_8833406_1 COG0155 Sulfite reductase, beta subunit (hemoprotein) K00366 - 1.7.7.1 0.000000000000000000000000001221 112.0
WLSH2_k127_8839283_0 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 426.0
WLSH2_k127_8839283_1 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) K00557 - 2.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 417.0
WLSH2_k127_8839283_2 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 401.0
WLSH2_k127_8839283_3 forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 383.0
WLSH2_k127_8925577_0 OmpA family - - - 3.71e-235 739.0
WLSH2_k127_8925577_1 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 388.0
WLSH2_k127_8925577_2 - - - - 0.00000000000000000000000000000000000000000000001641 172.0
WLSH2_k127_8925577_3 Protein of unknown function (DUF2846) - - - 0.00000000000000000000000000017 118.0
WLSH2_k127_8932744_0 GGDEF domain - - - 3.753e-235 741.0
WLSH2_k127_8932744_1 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 566.0
WLSH2_k127_8932744_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 519.0
WLSH2_k127_8932744_3 Glycolate oxidase subunit K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000009682 200.0
WLSH2_k127_8940626_0 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 481.0
WLSH2_k127_8940626_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 456.0
WLSH2_k127_8940626_2 outer membrane porin, OprD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 424.0
WLSH2_k127_8940626_3 mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 398.0
WLSH2_k127_8940626_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 306.0
WLSH2_k127_8940626_5 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000000000004472 199.0
WLSH2_k127_8940626_6 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000009331 163.0
WLSH2_k127_8940626_7 iron ion homeostasis K04758 - - 0.000000000000000000000000002108 113.0
WLSH2_k127_8940626_8 - - - - 0.000000000000000000001377 96.0
WLSH2_k127_8944622_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 2.554e-218 682.0
WLSH2_k127_8944622_1 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 469.0
WLSH2_k127_8944622_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 341.0
WLSH2_k127_8944622_3 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000001195 205.0
WLSH2_k127_8944622_4 Chorismate mutase K04782 - 4.2.99.21 0.0000000000000000000000000000000000000000000000000001307 187.0
WLSH2_k127_8944622_5 Transcriptional regulator K03892 - - 0.000000000000000000000000000000000000000000004353 165.0
WLSH2_k127_8944622_8 thiosulfate sulfurtransferase activity K01011 GO:0005575,GO:0005623,GO:0042597,GO:0044464 2.8.1.1,2.8.1.2 0.0000000000000000000003301 98.0
WLSH2_k127_8957848_0 TonB dependent receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 571.0
WLSH2_k127_8957848_1 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 307.0
WLSH2_k127_8957848_2 COGs COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase components K02013 - 3.6.3.34 0.00000000000000000000002162 101.0
WLSH2_k127_8964752_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1071.0
WLSH2_k127_8964752_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 291.0
WLSH2_k127_8966956_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.449e-221 689.0
WLSH2_k127_8966956_1 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002845 278.0
WLSH2_k127_9001956_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002831 245.0
WLSH2_k127_9001956_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000005247 226.0
WLSH2_k127_9001956_2 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000002629 150.0
WLSH2_k127_9031838_0 Belongs to the UPF0246 family K09861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 364.0
WLSH2_k127_9031838_1 PFAM FecR protein - - - 0.00000000000000000000000000000000000000000000000004554 182.0
WLSH2_k127_9031838_2 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000009544 127.0
WLSH2_k127_908179_0 chemotaxis protein K03407 - 2.7.13.3 0.0 1205.0
WLSH2_k127_908179_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 1.713e-209 658.0
WLSH2_k127_908179_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 544.0
WLSH2_k127_908179_3 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 425.0
WLSH2_k127_908179_4 chemotaxis protein K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 412.0
WLSH2_k127_908179_5 abc transporter atp-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 388.0
WLSH2_k127_908179_6 chemotaxis protein K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 299.0
WLSH2_k127_908179_7 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000000000000000000000000000000000000000002024 232.0
WLSH2_k127_908179_8 - - - - 0.00000000000007372 71.0
WLSH2_k127_9140614_0 protein involved in exopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 336.0
WLSH2_k127_9140614_1 Ankyrin repeat K06867,K21440 - - 0.000000000000000000000000000000000000004936 150.0
WLSH2_k127_9146759_0 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 596.0
WLSH2_k127_9146759_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 571.0
WLSH2_k127_9146759_2 COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain) K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 318.0
WLSH2_k127_9146759_3 - - - - 0.00000000000000000000000000000000000000000000000000002667 190.0
WLSH2_k127_9146759_4 - - - - 0.00000000000000000000000000000000000000000000000006834 180.0
WLSH2_k127_9146759_5 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000001603 151.0
WLSH2_k127_9148324_0 Major Facilitator - - - 2.31e-202 636.0
WLSH2_k127_9148324_1 Protein of unknown function (DUF808) K09781 - - 0.00000000000000000000000000000000000000000000000000000000000000000594 227.0
WLSH2_k127_9202186_0 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K03581 - 3.1.11.5 4.457e-218 679.0
WLSH2_k127_9202186_1 Domain of unknown function DUF21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 589.0
WLSH2_k127_9202186_10 Protein of unknown function VcgC/VcgE (DUF2780) - - - 0.00000000000000000000000000000000039 136.0
WLSH2_k127_9202186_2 Hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 535.0
WLSH2_k127_9202186_3 Protein of unknown function (DUF475) K09799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 525.0
WLSH2_k127_9202186_4 DnaJ domain protein K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 456.0
WLSH2_k127_9202186_5 Epimerase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 428.0
WLSH2_k127_9202186_6 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 391.0
WLSH2_k127_9202186_7 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000219 260.0
WLSH2_k127_9202186_8 PFAM Archaea bacterial proteins of K06921 - - 0.00000000000000000000000000000000000000000004515 162.0
WLSH2_k127_9202186_9 Cupin domain K11312 - - 0.00000000000000000000000000000000000000000008414 162.0
WLSH2_k127_9226921_0 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 565.0
WLSH2_k127_9226921_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 460.0
WLSH2_k127_9226921_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000002629 219.0
WLSH2_k127_9236102_0 Sulfatase - - - 2.123e-270 845.0
WLSH2_k127_9236102_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 6.141e-259 803.0
WLSH2_k127_9236102_10 ADP-L-glycero-D-manno-heptose-6-epimerase K03274 - 5.1.3.20 0.00000000000000000000002715 99.0
WLSH2_k127_9236102_11 - - - - 0.000000000563 70.0
WLSH2_k127_9236102_2 Alginate O-acetylation protein - - - 4.582e-211 664.0
WLSH2_k127_9236102_3 lipopolysaccharide core region biosynthetic process - - - 1.49e-209 659.0
WLSH2_k127_9236102_4 COG0859 ADP-heptose LPS heptosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 519.0
WLSH2_k127_9236102_5 heptosyltransferase ii K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 510.0
WLSH2_k127_9236102_6 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 418.0
WLSH2_k127_9236102_7 acetyltransferase (isoleucine patch superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 289.0
WLSH2_k127_9236102_8 PFAM O-Antigen K02847 - - 0.000000000000000000000000000000000000000000000000000002049 195.0
WLSH2_k127_9236102_9 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000001052 141.0
WLSH2_k127_9256771_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.741e-265 821.0
WLSH2_k127_9256771_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 381.0
WLSH2_k127_9256771_2 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000001264 212.0
WLSH2_k127_9256771_3 esterase of the alpha beta hydrolase fold K07002 - - 0.00000000000000000000001692 99.0
WLSH2_k127_9257884_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 370.0
WLSH2_k127_9257884_1 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 331.0
WLSH2_k127_9257884_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 323.0
WLSH2_k127_9257884_3 Glycosyl hydrolase family 3 K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000002256 194.0
WLSH2_k127_9257884_4 Preprotein translocase subunit SecG K03075 - - 0.000000000000000000000000000000000000001045 151.0
WLSH2_k127_9340895_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 9.465e-194 610.0
WLSH2_k127_9340895_1 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 559.0
WLSH2_k127_9340895_2 Pfam Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 315.0
WLSH2_k127_9340895_3 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000006055 156.0
WLSH2_k127_939042_0 COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase K15022 - 1.17.1.10 0.0 1332.0
WLSH2_k127_939042_1 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1288.0
WLSH2_k127_939042_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.591e-271 835.0
WLSH2_k127_939042_3 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 542.0
WLSH2_k127_939042_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 507.0
WLSH2_k127_939042_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 345.0
WLSH2_k127_939042_6 putative NADH-ubiquinone oxidoreductase chain E K00334 - 1.6.5.3 0.000000000000000000000000000000000000791 140.0
WLSH2_k127_939042_7 Phospholipid glycerol acyltransferase - - - 0.0000000000000000007781 86.0
WLSH2_k127_939042_8 Acetyltransferase (GNAT) domain - - - 0.0004317 43.0
WLSH2_k127_9422711_0 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 3.313e-304 936.0
WLSH2_k127_9422711_1 Nitrogenase protein alpha chain K02586 - 1.18.6.1 9.282e-296 910.0
WLSH2_k127_9422711_2 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 5.215e-253 790.0
WLSH2_k127_9422711_3 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 4.989e-251 782.0
WLSH2_k127_9422711_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 584.0
WLSH2_k127_9422711_6 nitrogen fixation protein FixT K02593 - - 0.00000000000000000000000000000001596 127.0
WLSH2_k127_9422711_7 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000001105 118.0
WLSH2_k127_9422711_8 thioredoxin peroxidase activity K11065 - 1.11.1.15 0.000000000003247 70.0
WLSH2_k127_9439499_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1082.0
WLSH2_k127_9439499_1 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 4.746e-217 675.0
WLSH2_k127_9439499_2 fumarate reductase, iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 9.796e-199 620.0
WLSH2_k127_9439499_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 599.0
WLSH2_k127_9439499_4 Heterodisulfide reductase subunit B K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 588.0
WLSH2_k127_9439499_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 441.0
WLSH2_k127_9439499_6 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 394.0
WLSH2_k127_9439499_7 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 288.0
WLSH2_k127_9439499_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000004616 135.0
WLSH2_k127_944094_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 562.0
WLSH2_k127_944094_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000008722 124.0
WLSH2_k127_9473335_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000002557 233.0
WLSH2_k127_9473335_1 cyclic nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000008607 224.0
WLSH2_k127_9473335_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000005279 127.0
WLSH2_k127_9473335_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0001025 46.0
WLSH2_k127_9485781_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.145e-283 872.0
WLSH2_k127_9485781_1 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 7.792e-199 623.0
WLSH2_k127_9485781_10 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000000000003013 214.0
WLSH2_k127_9485781_11 Protein of unknown function (DUF2393) - - - 0.00000000000000000000000000000000000000000000000000000000003018 209.0
WLSH2_k127_9485781_2 Radical SAM protein K07139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 568.0
WLSH2_k127_9485781_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 567.0
WLSH2_k127_9485781_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 459.0
WLSH2_k127_9485781_5 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 424.0
WLSH2_k127_9485781_6 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 389.0
WLSH2_k127_9485781_7 Protein of unknown function (DUF2393) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001207 254.0
WLSH2_k127_9485781_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003749 257.0
WLSH2_k127_9485781_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002791 249.0
WLSH2_k127_9506305_0 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 441.0
WLSH2_k127_9506305_1 Belongs to the DEAD box helicase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 440.0
WLSH2_k127_9506305_2 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 386.0
WLSH2_k127_9506305_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005071 278.0
WLSH2_k127_9506305_4 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001178 243.0
WLSH2_k127_9506305_5 AF0941-like - - - 0.000000000000000000000000000000000000000002703 156.0
WLSH2_k127_9534953_0 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 509.0
WLSH2_k127_9534953_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 481.0
WLSH2_k127_9534953_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 425.0
WLSH2_k127_9534953_3 - - - - 0.00000000000000096 80.0
WLSH2_k127_9560087_0 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 547.0
WLSH2_k127_9560087_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
WLSH2_k127_9560087_2 hmm pf01863 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000003357 220.0
WLSH2_k127_9573232_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1157.0
WLSH2_k127_9573232_1 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000003732 218.0
WLSH2_k127_9573232_2 RDD family - - - 0.000000000000003968 79.0
WLSH2_k127_9574313_0 chemotaxis protein - - - 9.429e-228 715.0
WLSH2_k127_9574313_1 4Fe-4S binding domain - - - 7.952e-207 646.0
WLSH2_k127_9574313_2 component of anaerobic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 359.0
WLSH2_k127_9574313_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 357.0
WLSH2_k127_9574313_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005145 232.0
WLSH2_k127_9574313_5 Protein conserved in bacteria K09943 - - 0.00000000000000000000000000000000000000000000000000000009569 198.0
WLSH2_k127_9578552_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1538.0
WLSH2_k127_9578552_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 8.942e-247 766.0
WLSH2_k127_9578552_2 rod shape-determining protein mreB K03569 - - 4.228e-210 654.0
WLSH2_k127_9578552_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 362.0
WLSH2_k127_9578552_4 Rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000000001472 186.0
WLSH2_k127_9582473_0 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 541.0
WLSH2_k127_9582473_1 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 495.0
WLSH2_k127_9582473_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 414.0
WLSH2_k127_9582473_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000001578 246.0
WLSH2_k127_9582473_4 Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000000000000000000000000000000005487 198.0
WLSH2_k127_9582473_5 GatB Yqey family protein K09117 - - 0.0000000000000000000006102 95.0
WLSH2_k127_9603314_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 2.724e-196 619.0
WLSH2_k127_9603314_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 512.0
WLSH2_k127_9603314_2 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 362.0
WLSH2_k127_9613483_0 methyltransferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 329.0
WLSH2_k127_9613483_1 protein-glutamate methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000004418 230.0
WLSH2_k127_9613803_0 glutamine synthetase K01915 - 6.3.1.2 5.012e-194 606.0
WLSH2_k127_9613803_1 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 490.0
WLSH2_k127_9613803_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 488.0
WLSH2_k127_9613803_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 486.0
WLSH2_k127_9613803_4 polyphosphate kinase K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 463.0
WLSH2_k127_9613803_5 PhoU family K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 370.0
WLSH2_k127_9613803_6 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 363.0
WLSH2_k127_9620502_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1268.0
WLSH2_k127_9620502_1 homoserine dehydrogenase K00003 - 1.1.1.3 7.385e-242 751.0
WLSH2_k127_9620502_2 Belongs to the aldehyde dehydrogenase family - - - 1.164e-235 734.0
WLSH2_k127_9620502_3 Aminotransferase K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 521.0
WLSH2_k127_9620502_4 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 321.0
WLSH2_k127_9620502_5 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000000000000000364 159.0
WLSH2_k127_9620502_6 - - - - 0.00000000000000000000000000000000000000009196 153.0
WLSH2_k127_9626654_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 408.0
WLSH2_k127_9626654_1 AMIN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001813 226.0
WLSH2_k127_9626654_2 - - - - 0.0000000000000000000000000000000007746 132.0
WLSH2_k127_9628695_0 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 424.0
WLSH2_k127_9628695_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 368.0
WLSH2_k127_9628695_2 PFAM sigma-54 factor interaction domain-containing protein K02584,K12266 - - 0.00000000000003519 74.0
WLSH2_k127_9646172_0 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 588.0
WLSH2_k127_9646172_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 310.0
WLSH2_k127_9688093_0 Stage II sporulation protein E (SpoIIE) - - - 8.684e-205 649.0
WLSH2_k127_9688093_1 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 320.0
WLSH2_k127_9688093_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000000000007899 211.0
WLSH2_k127_9688093_3 flagellar protein FliS K02422 - - 0.00000000000000000000000000000000000000000000000000000001784 199.0
WLSH2_k127_9688093_4 - - - - 0.000000000000000000000000000000000001988 139.0
WLSH2_k127_9688093_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000002607 109.0
WLSH2_k127_9689963_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0 1109.0
WLSH2_k127_9689963_1 argininosuccinate lyase K01755 - 4.3.2.1 9.256e-276 851.0
WLSH2_k127_9689963_2 Membrane-bound lytic murein transglycosylase C K08306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 416.0
WLSH2_k127_9689963_3 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001522 278.0
WLSH2_k127_9689963_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000006579 166.0
WLSH2_k127_9704769_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 434.0
WLSH2_k127_9704769_1 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 353.0
WLSH2_k127_9704769_2 Ferredoxin-type protein, NapH MauN family K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 344.0
WLSH2_k127_9704769_3 ferredoxin-type protein NapF K02572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003332 275.0
WLSH2_k127_9704769_4 nitrate reductase K02570 - - 0.00000000000000000000000000000000000000000000000000000000000000002136 224.0
WLSH2_k127_9704769_5 - - - - 0.000000000000000000000000000002998 121.0
WLSH2_k127_9752207_0 Circularly permuted ATP-grasp type 2 - - - 0.0 1044.0
WLSH2_k127_9752207_1 Putative amidoligase enzyme (DUF2126) - - - 4.799e-215 671.0
WLSH2_k127_9752207_2 Bacterial transglutaminase-like N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 380.0
WLSH2_k127_9779497_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.833e-301 933.0
WLSH2_k127_9810295_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 583.0
WLSH2_k127_9810295_1 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member - - - 0.000000000000000000000000000000000000000000000000000000000000000001493 229.0
WLSH2_k127_9812508_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 4.2.3.5 1.087e-201 631.0
WLSH2_k127_9812508_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 494.0
WLSH2_k127_9812508_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 392.0
WLSH2_k127_9812508_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000004735 245.0
WLSH2_k127_9812508_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000004831 220.0
WLSH2_k127_9812508_5 Belongs to the UPF0250 family - - - 0.000000000000000000000000000001369 123.0
WLSH2_k127_9812508_6 tetratricopeptide repeat - - - 0.0000000000000000002424 91.0
WLSH2_k127_9813885_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1062.0
WLSH2_k127_9844559_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1202.0
WLSH2_k127_9844559_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.0 1016.0
WLSH2_k127_9844559_2 membrane-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 347.0
WLSH2_k127_9844559_3 ankyrin repeat family protein - GO:0000151,GO:0000278,GO:0000281,GO:0000902,GO:0000904,GO:0000910,GO:0001508,GO:0002028,GO:0003008,GO:0003254,GO:0003674,GO:0003824,GO:0004842,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005794,GO:0005829,GO:0005856,GO:0005886,GO:0005911,GO:0006464,GO:0006807,GO:0006810,GO:0006888,GO:0006892,GO:0006893,GO:0006996,GO:0007009,GO:0007010,GO:0007016,GO:0007049,GO:0007154,GO:0007275,GO:0007399,GO:0007409,GO:0007528,GO:0008092,GO:0008104,GO:0008150,GO:0008152,GO:0009653,GO:0009893,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010256,GO:0010313,GO:0010468,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010649,GO:0010650,GO:0010765,GO:0010959,GO:0010960,GO:0012505,GO:0014704,GO:0014731,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016192,GO:0016323,GO:0016328,GO:0016528,GO:0016529,GO:0016567,GO:0016740,GO:0019222,GO:0019226,GO:0019228,GO:0019538,GO:0019787,GO:0019899,GO:0022008,GO:0022402,GO:0022407,GO:0022409,GO:0022607,GO:0022898,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030030,GO:0030054,GO:0030154,GO:0030155,GO:0030182,GO:0030315,GO:0030424,GO:0030425,GO:0030507,GO:0030674,GO:0031175,GO:0031594,GO:0031625,GO:0031674,GO:0032026,GO:0032386,GO:0032388,GO:0032409,GO:0032410,GO:0032411,GO:0032412,GO:0032413,GO:0032414,GO:0032446,GO:0032501,GO:0032502,GO:0032507,GO:0032879,GO:0032880,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033157,GO:0033267,GO:0033268,GO:0034110,GO:0034112,GO:0034613,GO:0034762,GO:0034763,GO:0034764,GO:0034765,GO:0034766,GO:0034767,GO:0035637,GO:0036211,GO:0036477,GO:0042221,GO:0042383,GO:0042391,GO:0042592,GO:0042886,GO:0042995,GO:0043001,GO:0043005,GO:0043034,GO:0043170,GO:0043194,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043266,GO:0043267,GO:0043269,GO:0043270,GO:0043271,GO:0043292,GO:0043412,GO:0044085,GO:0044091,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044291,GO:0044304,GO:0044325,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045184,GO:0045185,GO:0045202,GO:0045211,GO:0045296,GO:0045760,GO:0045785,GO:0045838,GO:0046907,GO:0048193,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050808,GO:0050839,GO:0050877,GO:0050896,GO:0051049,GO:0051050,GO:0051051,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051235,GO:0051301,GO:0051641,GO:0051649,GO:0051651,GO:0051716,GO:0055065,GO:0055080,GO:0060090,GO:0060255,GO:0060341,GO:0061024,GO:0061564,GO:0061640,GO:0061951,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070647,GO:0070727,GO:0070887,GO:0071241,GO:0071248,GO:0071286,GO:0071702,GO:0071704,GO:0071705,GO:0071709,GO:0071840,GO:0071944,GO:0072507,GO:0072657,GO:0072658,GO:0072659,GO:0072660,GO:0090087,GO:0090150,GO:0090313,GO:0090314,GO:0090316,GO:0097060,GO:0097447,GO:0097458,GO:0098590,GO:0098771,GO:0098794,GO:0098876,GO:0098900,GO:0098901,GO:0098902,GO:0099080,GO:0099081,GO:0099512,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0140096,GO:1900825,GO:1900827,GO:1901016,GO:1901017,GO:1901379,GO:1901380,GO:1901564,GO:1902259,GO:1902260,GO:1902305,GO:1902307,GO:1902494,GO:1903047,GO:1903533,GO:1903817,GO:1903827,GO:1903829,GO:1904062,GO:1904063,GO:1904064,GO:1904181,GO:1904951,GO:1905475,GO:1905477,GO:1990234,GO:1990778,GO:2000649,GO:2000651,GO:2001257,GO:2001258,GO:2001259 - 0.00002288 53.0
WLSH2_k127_9916724_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1200.0
WLSH2_k127_9916724_1 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 489.0
WLSH2_k127_9916724_2 - - - - 0.000000000000009247 73.0
WLSH2_k127_9916724_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000003329 63.0
WLSH2_k127_9944083_0 ABC transporter K11085 - - 1.346e-301 932.0
WLSH2_k127_9944083_2 Glycosyltransferase - - - 0.0000000000000000000000000000000000000002128 151.0
WLSH2_k127_9944083_3 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000138 129.0
WLSH2_k127_9948732_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 555.0
WLSH2_k127_9948732_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 500.0
WLSH2_k127_9948732_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 465.0
WLSH2_k127_9948732_3 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 426.0
WLSH2_k127_9948732_5 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 336.0
WLSH2_k127_9948732_6 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 273.0
WLSH2_k127_9948732_7 Protein conserved in bacteria K09859 - - 0.00000000000000000002643 96.0
WLSH2_k127_9948732_8 Protein of unknown function (DUF1425) - - - 0.000000000002492 73.0