Overview

ID MAG04194
Name WLSH2_bin.12
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Acidiferrobacterales
Family UBA6901
Genus UBA6901
Species
Assembly information
Completeness (%) 71.86
Contamination (%) 3.62
GC content (%) 62.0
N50 (bp) 14,357
Genome size (bp) 1,931,256

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1938

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10032438_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 474.0
WLSH2_k127_10032438_1 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 317.0
WLSH2_k127_10032438_2 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 289.0
WLSH2_k127_10032438_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000001038 250.0
WLSH2_k127_10092576_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 7.631e-200 629.0
WLSH2_k127_10092576_1 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 580.0
WLSH2_k127_10092576_10 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 340.0
WLSH2_k127_10092576_11 PFAM MoeZ MoeB domain K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 329.0
WLSH2_k127_10092576_12 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 323.0
WLSH2_k127_10092576_13 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 299.0
WLSH2_k127_10092576_14 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005851 276.0
WLSH2_k127_10092576_15 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions K05501 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000004857 228.0
WLSH2_k127_10092576_16 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000003865 225.0
WLSH2_k127_10092576_17 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000001108 209.0
WLSH2_k127_10092576_18 auxin efflux carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000236 207.0
WLSH2_k127_10092576_19 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000001186 198.0
WLSH2_k127_10092576_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 543.0
WLSH2_k127_10092576_20 PFAM Ion transport 2 domain protein - - - 0.0000000000000000000000000000000000003337 144.0
WLSH2_k127_10092576_21 - - - - 0.0000000000000000000000000000000000003887 143.0
WLSH2_k127_10092576_22 EamA-like transporter family - - - 0.00000000000000000000000000000001975 135.0
WLSH2_k127_10092576_23 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000009 130.0
WLSH2_k127_10092576_24 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000009668 116.0
WLSH2_k127_10092576_25 - - - - 0.00000000000000000005805 94.0
WLSH2_k127_10092576_26 Cytochrome c - - - 0.000000002589 62.0
WLSH2_k127_10092576_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 489.0
WLSH2_k127_10092576_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 490.0
WLSH2_k127_10092576_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 469.0
WLSH2_k127_10092576_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 445.0
WLSH2_k127_10092576_7 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 424.0
WLSH2_k127_10092576_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 403.0
WLSH2_k127_10092576_9 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 407.0
WLSH2_k127_10172002_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1759.0
WLSH2_k127_10172002_1 Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000000000000000000000000000000002968 203.0
WLSH2_k127_10172002_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000005219 135.0
WLSH2_k127_10192545_0 FAD linked - - - 4.145e-292 904.0
WLSH2_k127_10192545_1 - - - - 0.00000000000000000000000003145 113.0
WLSH2_k127_10192545_2 lysine methyltransferase K07117 - - 0.0000000000000000000007388 100.0
WLSH2_k127_10212575_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 496.0
WLSH2_k127_10212575_1 Transcriptional regulatory protein, C terminal K07662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 318.0
WLSH2_k127_10212575_2 serine-type peptidase activity K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 318.0
WLSH2_k127_10212575_3 Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system K01990,K09695 - - 0.0000000000000000000000000000000000001244 143.0
WLSH2_k127_10212575_4 ATP-independent chaperone mediated protein folding K06006 - - 0.0006503 50.0
WLSH2_k127_10290852_0 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 420.0
WLSH2_k127_10290852_1 Abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 368.0
WLSH2_k127_10290852_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 325.0
WLSH2_k127_10290852_3 oxidoreductase K06940 - - 0.00000000000000000000000000000000000000000000000000000000000001129 216.0
WLSH2_k127_10290852_4 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000003699 181.0
WLSH2_k127_10290852_5 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000000000000008533 174.0
WLSH2_k127_10290852_6 Cytochrome C' - - - 0.000000000000000000000001125 108.0
WLSH2_k127_10309794_0 GTP-binding protein TypA K06207 - - 2.504e-284 885.0
WLSH2_k127_10309794_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 408.0
WLSH2_k127_10309794_2 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000001619 242.0
WLSH2_k127_10309794_3 Sulfurtransferase TusA - - - 0.000000000000000000002673 94.0
WLSH2_k127_10309794_4 protein conserved in bacteria K09908 - - 0.000000000000002996 82.0
WLSH2_k127_10309794_5 Belongs to the sulfur carrier protein TusA family - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000002079 59.0
WLSH2_k127_10359616_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.0 1110.0
WLSH2_k127_10359616_1 Belongs to the glycosyl hydrolase 57 family - - - 1.952e-223 706.0
WLSH2_k127_10359616_10 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 444.0
WLSH2_k127_10359616_11 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 441.0
WLSH2_k127_10359616_12 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 349.0
WLSH2_k127_10359616_13 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 311.0
WLSH2_k127_10359616_14 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 290.0
WLSH2_k127_10359616_15 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002432 276.0
WLSH2_k127_10359616_16 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000008415 241.0
WLSH2_k127_10359616_17 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000006617 244.0
WLSH2_k127_10359616_18 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000004288 235.0
WLSH2_k127_10359616_19 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000006604 220.0
WLSH2_k127_10359616_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.299e-221 692.0
WLSH2_k127_10359616_20 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000001266 203.0
WLSH2_k127_10359616_21 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.00000000000000000000000000000000000000000000000000000399 195.0
WLSH2_k127_10359616_22 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000003523 193.0
WLSH2_k127_10359616_23 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000188 151.0
WLSH2_k127_10359616_24 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000000000005092 139.0
WLSH2_k127_10359616_25 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000879 45.0
WLSH2_k127_10359616_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 5.878e-218 693.0
WLSH2_k127_10359616_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism - - - 1.039e-215 678.0
WLSH2_k127_10359616_5 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 610.0
WLSH2_k127_10359616_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 582.0
WLSH2_k127_10359616_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 542.0
WLSH2_k127_10359616_8 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 462.0
WLSH2_k127_10359616_9 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 450.0
WLSH2_k127_10461895_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 565.0
WLSH2_k127_10461895_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000001462 168.0
WLSH2_k127_10461895_2 - - - - 0.000000182 59.0
WLSH2_k127_10521642_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.024e-245 765.0
WLSH2_k127_10521642_1 4Fe-4S single cluster domain - - - 1.014e-197 619.0
WLSH2_k127_10521642_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 364.0
WLSH2_k127_10521642_11 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 347.0
WLSH2_k127_10521642_12 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 354.0
WLSH2_k127_10521642_13 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 319.0
WLSH2_k127_10521642_14 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 302.0
WLSH2_k127_10521642_15 pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 325.0
WLSH2_k127_10521642_16 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 301.0
WLSH2_k127_10521642_17 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006855 279.0
WLSH2_k127_10521642_18 MltA-interacting protein MipA K07274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003523 272.0
WLSH2_k127_10521642_19 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004962 269.0
WLSH2_k127_10521642_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 2.674e-194 610.0
WLSH2_k127_10521642_20 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003024 246.0
WLSH2_k127_10521642_21 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000003033 223.0
WLSH2_k127_10521642_22 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000000009617 224.0
WLSH2_k127_10521642_23 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000002425 206.0
WLSH2_k127_10521642_24 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000000000005685 150.0
WLSH2_k127_10521642_25 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000002865 142.0
WLSH2_k127_10521642_26 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000000000001576 117.0
WLSH2_k127_10521642_27 Protein of unknown function (DUF3617) - - - 0.00000000000000000006546 95.0
WLSH2_k127_10521642_29 - - - - 0.0000000000000211 77.0
WLSH2_k127_10521642_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 565.0
WLSH2_k127_10521642_30 - - - - 0.000001979 56.0
WLSH2_k127_10521642_31 - - - - 0.000003172 49.0
WLSH2_k127_10521642_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 543.0
WLSH2_k127_10521642_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 471.0
WLSH2_k127_10521642_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 411.0
WLSH2_k127_10521642_7 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 406.0
WLSH2_k127_10521642_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 398.0
WLSH2_k127_10521642_9 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 398.0
WLSH2_k127_10531463_0 2 iron, 2 sulfur cluster binding - - - 0.0 1095.0
WLSH2_k127_10531463_1 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000003537 227.0
WLSH2_k127_10531463_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000001117 224.0
WLSH2_k127_10531463_3 PFAM Cyclic nucleotide-binding K21563 - - 0.0000000000000000000003889 99.0
WLSH2_k127_10531463_4 Protein of unknown function (DUF2892) - - - 0.0000000000000000001539 92.0
WLSH2_k127_10612466_0 Putative nucleotidyltransferase substrate binding domain K07182 - - 6.122e-261 818.0
WLSH2_k127_10612466_1 Ion channel K10716 - - 2.721e-211 670.0
WLSH2_k127_10612466_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001637 270.0
WLSH2_k127_10612466_3 - - - - 0.0000000000000000000000000000000000000000000000000009876 186.0
WLSH2_k127_10612466_4 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000005641 177.0
WLSH2_k127_10612466_5 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000005073 185.0
WLSH2_k127_10612466_6 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000000002804 139.0
WLSH2_k127_10612466_7 Sodium:solute symporter family - - - 0.00000000000000000000000000000000001711 139.0
WLSH2_k127_10612466_8 Nad-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000009011 140.0
WLSH2_k127_10612466_9 - - - - 0.000000000000000000009283 93.0
WLSH2_k127_10730739_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1364.0
WLSH2_k127_10730739_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 496.0
WLSH2_k127_10730739_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001166 269.0
WLSH2_k127_10730739_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000002726 261.0
WLSH2_k127_10730739_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000002124 246.0
WLSH2_k127_10730739_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000004326 237.0
WLSH2_k127_10730739_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000001108 217.0
WLSH2_k127_10730739_7 PFAM Smr - - - 0.000000000000000000000000000000000000000000000001431 180.0
WLSH2_k127_10730739_8 transcriptional regulator K07736 - - 0.0000000000000000003134 93.0
WLSH2_k127_10778517_0 Belongs to the UPF0061 (SELO) family - - - 2.372e-201 639.0
WLSH2_k127_10778517_1 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005097 253.0
WLSH2_k127_10778517_2 conserved protein (DUF2132) - - - 0.000000000001289 67.0
WLSH2_k127_10820040_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 463.0
WLSH2_k127_10820040_1 response regulator K20977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 402.0
WLSH2_k127_10820040_2 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 347.0
WLSH2_k127_10820040_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 327.0
WLSH2_k127_10820040_4 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000002083 268.0
WLSH2_k127_10820040_5 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000003698 229.0
WLSH2_k127_10820040_6 response regulator K02488 - 2.7.7.65 0.0000000000000000000000000000000004216 138.0
WLSH2_k127_10820040_7 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K20978 - - 0.000000000000000000000000000002231 124.0
WLSH2_k127_10820040_8 response regulator receiver - - - 0.000000000000000000002144 101.0
WLSH2_k127_10855570_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1361.0
WLSH2_k127_10855570_1 Dehydrogenase K00382 - 1.8.1.4 3.224e-275 857.0
WLSH2_k127_10855570_10 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06020 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 323.0
WLSH2_k127_10855570_11 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005509 280.0
WLSH2_k127_10855570_12 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000002967 227.0
WLSH2_k127_10855570_13 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000001915 222.0
WLSH2_k127_10855570_14 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000001544 240.0
WLSH2_k127_10855570_15 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000003762 185.0
WLSH2_k127_10855570_16 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000002641 173.0
WLSH2_k127_10855570_17 Thioredoxin-like domain K03805 - - 0.000000000000000000000000000000000000363 147.0
WLSH2_k127_10855570_18 MarC family integral membrane protein - - - 0.0000000000000000000000000000000007867 139.0
WLSH2_k127_10855570_19 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000001392 134.0
WLSH2_k127_10855570_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 4.816e-260 813.0
WLSH2_k127_10855570_20 COG2998 ABC-type tungstate transport system, permease component K05772 - - 0.000000000000000000000000001439 130.0
WLSH2_k127_10855570_21 FR47-like protein - - - 0.000000000000000000004533 100.0
WLSH2_k127_10855570_22 PFAM cytochrome c, class I K17230 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000006611 76.0
WLSH2_k127_10855570_23 Putative zinc-finger - - - 0.00000001056 61.0
WLSH2_k127_10855570_3 Diguanylate cyclase - - - 3.014e-231 744.0
WLSH2_k127_10855570_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.156e-225 704.0
WLSH2_k127_10855570_5 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 512.0
WLSH2_k127_10855570_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17229 - 1.8.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 513.0
WLSH2_k127_10855570_7 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 471.0
WLSH2_k127_10855570_8 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 419.0
WLSH2_k127_10855570_9 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 355.0
WLSH2_k127_10857637_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.121e-206 657.0
WLSH2_k127_10857637_1 Aspartate ammonia-lyase K01744 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319 4.3.1.1 6.177e-206 650.0
WLSH2_k127_10857637_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003424 256.0
WLSH2_k127_10857637_11 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000002727 224.0
WLSH2_k127_10857637_12 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000003154 216.0
WLSH2_k127_10857637_13 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000004331 214.0
WLSH2_k127_10857637_14 pfam nudix K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000001335 207.0
WLSH2_k127_10857637_15 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000002307 205.0
WLSH2_k127_10857637_16 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000003927 205.0
WLSH2_k127_10857637_17 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000006415 165.0
WLSH2_k127_10857637_18 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000001531 176.0
WLSH2_k127_10857637_19 Membrane - - - 0.000000000000000000000000000000000000002525 152.0
WLSH2_k127_10857637_2 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 525.0
WLSH2_k127_10857637_20 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000007209 151.0
WLSH2_k127_10857637_21 PFAM CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000007087 151.0
WLSH2_k127_10857637_22 LysM domain - - - 0.00000000000000000000000000000000228 134.0
WLSH2_k127_10857637_23 AntiSigma factor K09004 - - 0.0000000000000000000000000000008176 135.0
WLSH2_k127_10857637_24 Thioredoxin-like - - - 0.000000000000000000000005176 107.0
WLSH2_k127_10857637_25 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.00000000000000001329 87.0
WLSH2_k127_10857637_26 Protein of unknown function (DUF3108) - - - 0.000000000000001016 88.0
WLSH2_k127_10857637_27 - - - - 0.0000000000000135 79.0
WLSH2_k127_10857637_28 membrane - - - 0.0000000000000211 79.0
WLSH2_k127_10857637_29 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' K03556 GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030246,GO:0031323,GO:0031326,GO:0042802,GO:0044238,GO:0048031,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070492,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.000004154 53.0
WLSH2_k127_10857637_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 488.0
WLSH2_k127_10857637_4 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 426.0
WLSH2_k127_10857637_5 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 359.0
WLSH2_k127_10857637_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 317.0
WLSH2_k127_10857637_7 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 295.0
WLSH2_k127_10857637_8 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 287.0
WLSH2_k127_10857637_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
WLSH2_k127_10899429_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 1.347e-217 682.0
WLSH2_k127_10899429_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 464.0
WLSH2_k127_10899429_10 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000003753 230.0
WLSH2_k127_10899429_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000102 215.0
WLSH2_k127_10899429_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000005091 204.0
WLSH2_k127_10899429_13 transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000002264 207.0
WLSH2_k127_10899429_14 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000007603 193.0
WLSH2_k127_10899429_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000002866 189.0
WLSH2_k127_10899429_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000004992 179.0
WLSH2_k127_10899429_17 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000001133 183.0
WLSH2_k127_10899429_18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000105 153.0
WLSH2_k127_10899429_19 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000005552 151.0
WLSH2_k127_10899429_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 442.0
WLSH2_k127_10899429_20 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000001554 148.0
WLSH2_k127_10899429_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001047 147.0
WLSH2_k127_10899429_22 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000002644 139.0
WLSH2_k127_10899429_23 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000006406 124.0
WLSH2_k127_10899429_24 Ribosomal protein L30 K02907 - - 0.0000000000000000001117 92.0
WLSH2_k127_10899429_25 Histidine kinase K20974 - 2.7.13.3 0.000000000000003738 83.0
WLSH2_k127_10899429_26 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002292 72.0
WLSH2_k127_10899429_27 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000006646 73.0
WLSH2_k127_10899429_28 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000001472 55.0
WLSH2_k127_10899429_3 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 452.0
WLSH2_k127_10899429_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 333.0
WLSH2_k127_10899429_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 325.0
WLSH2_k127_10899429_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 282.0
WLSH2_k127_10899429_7 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001115 281.0
WLSH2_k127_10899429_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001619 242.0
WLSH2_k127_10899429_9 Belongs to the universal ribosomal protein uS5 family K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005946 240.0
WLSH2_k127_10973868_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 359.0
WLSH2_k127_10973868_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 338.0
WLSH2_k127_10973868_10 Type II transport protein GspH - - - 0.000000000000000000000001104 109.0
WLSH2_k127_10973868_11 Domain of unknown function (DUF4845) - - - 0.00000008707 60.0
WLSH2_k127_10973868_2 carboxylate-amine ligase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 345.0
WLSH2_k127_10973868_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 312.0
WLSH2_k127_10973868_4 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002215 278.0
WLSH2_k127_10973868_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001984 256.0
WLSH2_k127_10973868_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000001991 203.0
WLSH2_k127_10973868_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000001613 131.0
WLSH2_k127_10973868_8 Bacterial Fe(2+) trafficking - - - 0.000000000000000000000000000004592 121.0
WLSH2_k127_10973868_9 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000000123 111.0
WLSH2_k127_10983991_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 334.0
WLSH2_k127_10983991_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002502 261.0
WLSH2_k127_10983991_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000002021 212.0
WLSH2_k127_10983991_3 Clan AA aspartic protease K06985 - - 0.00000000000000000000000000000000000000000001308 169.0
WLSH2_k127_10983991_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000004828 149.0
WLSH2_k127_10983991_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000146 152.0
WLSH2_k127_11006290_0 COG1530 Ribonucleases G and E K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 576.0
WLSH2_k127_11006290_1 Protein of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 469.0
WLSH2_k127_11006290_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 377.0
WLSH2_k127_11006290_3 TldD PmbA family protein K03568 - - 0.00000000000001648 81.0
WLSH2_k127_11158093_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2103.0
WLSH2_k127_11158093_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2048.0
WLSH2_k127_11158093_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000001064 80.0
WLSH2_k127_11158093_11 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000005732 51.0
WLSH2_k127_11158093_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 337.0
WLSH2_k127_11158093_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006126 278.0
WLSH2_k127_11158093_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000001195 232.0
WLSH2_k127_11158093_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000002145 231.0
WLSH2_k127_11158093_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000004224 226.0
WLSH2_k127_11158093_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000002716 213.0
WLSH2_k127_11158093_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000002982 155.0
WLSH2_k127_11158093_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000001805 106.0
WLSH2_k127_11178934_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.668e-203 638.0
WLSH2_k127_11178934_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 618.0
WLSH2_k127_11178934_10 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 364.0
WLSH2_k127_11178934_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 356.0
WLSH2_k127_11178934_12 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000203 271.0
WLSH2_k127_11178934_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000001832 160.0
WLSH2_k127_11178934_14 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000002671 77.0
WLSH2_k127_11178934_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 601.0
WLSH2_k127_11178934_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 539.0
WLSH2_k127_11178934_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 485.0
WLSH2_k127_11178934_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 484.0
WLSH2_k127_11178934_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 467.0
WLSH2_k127_11178934_7 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 440.0
WLSH2_k127_11178934_8 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 407.0
WLSH2_k127_11178934_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 372.0
WLSH2_k127_11224886_0 Bacterial protein of unknown function (DUF853) K06915 - - 4.089e-196 622.0
WLSH2_k127_11224886_1 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 374.0
WLSH2_k127_11224886_2 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000008678 231.0
WLSH2_k127_11224886_3 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000007131 221.0
WLSH2_k127_11229980_0 Sodium calcium exchanger K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 305.0
WLSH2_k127_11229980_1 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000000000000000000000000000000001986 228.0
WLSH2_k127_11229980_2 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000001838 171.0
WLSH2_k127_11230742_0 Multicopper oxidase - - - 2.476e-287 892.0
WLSH2_k127_11230742_1 PFAM AMP-dependent synthetase and ligase K00666 - - 1.152e-240 756.0
WLSH2_k127_11230742_10 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000001698 206.0
WLSH2_k127_11230742_11 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000003047 182.0
WLSH2_k127_11230742_12 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000000000000000004272 168.0
WLSH2_k127_11230742_13 3-carboxymuconate cyclase quinoprotein amine dehydrogenase, beta chain-like - - - 0.000000000000000000000000000000000000007771 167.0
WLSH2_k127_11230742_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000005726 147.0
WLSH2_k127_11230742_15 Cytochrome c - - - 0.0000000000000000000000000000009598 129.0
WLSH2_k127_11230742_16 - - - - 0.0000000000000000000000000001088 117.0
WLSH2_k127_11230742_17 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000000000003607 95.0
WLSH2_k127_11230742_18 Cytochrome c, class I - - - 0.00000000000002078 80.0
WLSH2_k127_11230742_19 Putative zinc- or iron-chelating domain - - - 0.0000001912 55.0
WLSH2_k127_11230742_2 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 424.0
WLSH2_k127_11230742_20 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.0000002456 64.0
WLSH2_k127_11230742_3 antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 426.0
WLSH2_k127_11230742_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 421.0
WLSH2_k127_11230742_5 Histidine Phosphotransfer domain K10715,K20974 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 446.0
WLSH2_k127_11230742_6 Copper resistance K07233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 350.0
WLSH2_k127_11230742_7 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 333.0
WLSH2_k127_11230742_8 Enoyl-CoA hydratase/isomerase K13816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005712 273.0
WLSH2_k127_11230742_9 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001816 238.0
WLSH2_k127_11233425_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 522.0
WLSH2_k127_11233425_1 Acid phosphatase homologues K12978 - - 0.000000000000000000000000000000000000000000000000000000001608 211.0
WLSH2_k127_11233425_2 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000000003214 96.0
WLSH2_k127_11252971_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 7.567e-317 975.0
WLSH2_k127_11252971_1 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 334.0
WLSH2_k127_11252971_2 Urea ABC transporter, urea binding protein K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 284.0
WLSH2_k127_11252971_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008306 259.0
WLSH2_k127_11252971_4 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004703 239.0
WLSH2_k127_11252971_5 Urease, gamma subunit K01430 - 3.5.1.5 0.00000000000000000000000000000000000000000000000008307 178.0
WLSH2_k127_11252971_6 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.0000000000000000000000000000000000000000000007358 168.0
WLSH2_k127_11252971_7 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000000000000218 160.0
WLSH2_k127_11252971_8 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000001201 67.0
WLSH2_k127_11258947_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 621.0
WLSH2_k127_11258947_1 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 516.0
WLSH2_k127_11258947_10 EamA-like transporter family - - - 0.0000000000000000000000000000000006604 136.0
WLSH2_k127_11258947_11 protein conserved in bacteria K09928 - - 0.000000000000000000000556 100.0
WLSH2_k127_11258947_12 protein conserved in bacteria K09928 - - 0.00000000000000003571 89.0
WLSH2_k127_11258947_13 Protein of unknown function (DUF721) - - - 0.0000003293 58.0
WLSH2_k127_11258947_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 300.0
WLSH2_k127_11258947_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 301.0
WLSH2_k127_11258947_4 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005516 250.0
WLSH2_k127_11258947_5 peptidase M48, Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000001484 234.0
WLSH2_k127_11258947_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000001986 192.0
WLSH2_k127_11258947_7 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000000001058 169.0
WLSH2_k127_11258947_8 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000002339 150.0
WLSH2_k127_11258947_9 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000001133 139.0
WLSH2_k127_11276705_0 peptidase K01414 - 3.4.24.70 1.642e-241 756.0
WLSH2_k127_11276705_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 7.486e-210 661.0
WLSH2_k127_11276705_10 Domain of unknown function (DUF4124) - - - 0.000000000000000000005222 101.0
WLSH2_k127_11276705_11 Phospholipid methyltransferase - - - 0.000000000000000007805 91.0
WLSH2_k127_11276705_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 469.0
WLSH2_k127_11276705_3 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 376.0
WLSH2_k127_11276705_4 Elongator protein 3, MiaB family, Radical SAM K03644 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 309.0
WLSH2_k127_11276705_5 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000007991 226.0
WLSH2_k127_11276705_6 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000001095 225.0
WLSH2_k127_11276705_7 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000002145 205.0
WLSH2_k127_11276705_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000002921 184.0
WLSH2_k127_11276705_9 organic phosphonate transport K02044 - - 0.0000000000000000000000000000000000009869 150.0
WLSH2_k127_11278334_0 leucine-zipper of insertion element IS481 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 499.0
WLSH2_k127_11278334_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 379.0
WLSH2_k127_11278334_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 319.0
WLSH2_k127_11278334_3 carbonic - - - 0.0000000000000000000000000000000000000000000000000000000000000001363 226.0
WLSH2_k127_11278334_4 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000004184 213.0
WLSH2_k127_11278334_5 Putative member of DMT superfamily (DUF486) - - - 0.0000000000000000000000000000000000000000000000000002935 188.0
WLSH2_k127_11348835_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 564.0
WLSH2_k127_11348835_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 396.0
WLSH2_k127_11348835_10 Belongs to the frataxin K06202 - - 0.0000000000000000000000119 108.0
WLSH2_k127_11348835_11 - - - - 0.000000000000001447 81.0
WLSH2_k127_11348835_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 344.0
WLSH2_k127_11348835_3 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 295.0
WLSH2_k127_11348835_4 coa-binding K06929 - - 0.00000000000000000000000000000000000000000000000002916 182.0
WLSH2_k127_11348835_5 PFAM Outer membrane lipoprotein Slp K07285 - - 0.0000000000000000000000000000000000000000005815 162.0
WLSH2_k127_11348835_6 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000279 147.0
WLSH2_k127_11348835_7 Dodecin K09165 - - 0.000000000000000000000000001447 118.0
WLSH2_k127_11348835_8 PFAM Peptidase S24 S26A S26B, conserved region - - - 0.0000000000000000000000005133 107.0
WLSH2_k127_11348835_9 PFAM FIST C domain - - - 0.000000000000000000000001054 104.0
WLSH2_k127_11424849_0 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 602.0
WLSH2_k127_11424849_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 453.0
WLSH2_k127_11424849_10 Protein of unknown function (DUF3579) - - - 0.000000000000005973 79.0
WLSH2_k127_11424849_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009582 383.0
WLSH2_k127_11424849_3 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 362.0
WLSH2_k127_11424849_4 PFAM DegT DnrJ EryC1 StrS aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 361.0
WLSH2_k127_11424849_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 345.0
WLSH2_k127_11424849_6 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000003451 254.0
WLSH2_k127_11424849_7 Multicopper oxidase - - - 0.000000000000000000000000000000000000004811 157.0
WLSH2_k127_11424849_8 Multicopper oxidase - - - 0.00000000000000000000000000001621 134.0
WLSH2_k127_11424849_9 Electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000002157 122.0
WLSH2_k127_11514196_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 9.176e-223 711.0
WLSH2_k127_11514196_1 Fructosamine kinase - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 355.0
WLSH2_k127_11514196_2 Pfam Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002462 275.0
WLSH2_k127_11514196_3 Patatin-like phospholipase - - - 0.0000000003225 70.0
WLSH2_k127_1193206_0 Amidohydrolase family K01465 - 3.5.2.3 7.341e-197 621.0
WLSH2_k127_1193206_1 PFAM aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 484.0
WLSH2_k127_1193206_10 PFAM VanZ - - - 0.000000000000000003193 88.0
WLSH2_k127_1193206_11 Protein required for attachment to host cells - - - 0.0000000001587 63.0
WLSH2_k127_1193206_12 - - - - 0.0000161 53.0
WLSH2_k127_1193206_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 416.0
WLSH2_k127_1193206_3 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 376.0
WLSH2_k127_1193206_4 HAD-superfamily hydrolase subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 359.0
WLSH2_k127_1193206_5 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002053 276.0
WLSH2_k127_1193206_7 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.000000000000000000000000000000000000000000000000000000001162 204.0
WLSH2_k127_1193206_8 - - - - 0.0000000000000000000000000000000000000000000000000000297 193.0
WLSH2_k127_1193206_9 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000006974 167.0
WLSH2_k127_1230838_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 9.598e-292 926.0
WLSH2_k127_1230838_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 6.144e-249 775.0
WLSH2_k127_1230838_10 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003773 250.0
WLSH2_k127_1230838_11 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000002073 240.0
WLSH2_k127_1230838_12 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000001079 217.0
WLSH2_k127_1230838_13 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000004015 205.0
WLSH2_k127_1230838_14 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000003873 157.0
WLSH2_k127_1230838_15 SnoaL-like domain - - - 0.00000000000000000000000000000000004051 139.0
WLSH2_k127_1230838_16 PFAM Rhodanese domain protein - - - 0.000000000000000000000000000000001146 132.0
WLSH2_k127_1230838_17 Cephalosporin hydroxylase - - - 0.0000000000000000000000000000001228 134.0
WLSH2_k127_1230838_18 protein conserved in bacteria - - - 0.000000000000000000009182 101.0
WLSH2_k127_1230838_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 512.0
WLSH2_k127_1230838_3 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 442.0
WLSH2_k127_1230838_4 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 435.0
WLSH2_k127_1230838_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 366.0
WLSH2_k127_1230838_6 Mitochondrial fission ELM1 K07276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 310.0
WLSH2_k127_1230838_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 312.0
WLSH2_k127_1230838_8 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001528 272.0
WLSH2_k127_1230838_9 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000005396 258.0
WLSH2_k127_1250739_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1163.0
WLSH2_k127_1250739_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.266e-267 830.0
WLSH2_k127_1250739_10 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 458.0
WLSH2_k127_1250739_11 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 443.0
WLSH2_k127_1250739_12 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 461.0
WLSH2_k127_1250739_13 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 393.0
WLSH2_k127_1250739_14 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 336.0
WLSH2_k127_1250739_15 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 329.0
WLSH2_k127_1250739_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 328.0
WLSH2_k127_1250739_17 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007296 275.0
WLSH2_k127_1250739_18 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000001812 262.0
WLSH2_k127_1250739_19 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003607 239.0
WLSH2_k127_1250739_2 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 1.244e-263 825.0
WLSH2_k127_1250739_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002806 253.0
WLSH2_k127_1250739_21 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000002918 218.0
WLSH2_k127_1250739_22 Protein of unknown function, DUF484 - - - 0.0000000000000000000000000000000000000000000000000000000001006 220.0
WLSH2_k127_1250739_23 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000452 203.0
WLSH2_k127_1250739_24 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000003559 203.0
WLSH2_k127_1250739_25 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000007627 203.0
WLSH2_k127_1250739_26 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000000000000005804 198.0
WLSH2_k127_1250739_27 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000000001482 186.0
WLSH2_k127_1250739_28 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K05997,K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0019538,GO:0022607,GO:0031163,GO:0034986,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901564 - 0.000000000000000000000000000000000000000000000007217 177.0
WLSH2_k127_1250739_29 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.0000000000000000000000000000000000000003882 154.0
WLSH2_k127_1250739_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.784e-228 715.0
WLSH2_k127_1250739_30 protein conserved in bacteria - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - 0.0000000000000000000000000000000002862 141.0
WLSH2_k127_1250739_31 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000000001118 127.0
WLSH2_k127_1250739_32 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.00000000000000000000000000151 114.0
WLSH2_k127_1250739_33 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000000000000006623 106.0
WLSH2_k127_1250739_34 Modulates RecA activity K03565 - - 0.00000000000008966 73.0
WLSH2_k127_1250739_35 Recombinase zinc beta ribbon domain K06400 - - 0.00000000003237 66.0
WLSH2_k127_1250739_36 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000003681 56.0
WLSH2_k127_1250739_37 - - - - 0.000002366 53.0
WLSH2_k127_1250739_38 - - - - 0.00002329 52.0
WLSH2_k127_1250739_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.225e-213 667.0
WLSH2_k127_1250739_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 5.968e-198 623.0
WLSH2_k127_1250739_6 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 541.0
WLSH2_k127_1250739_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 517.0
WLSH2_k127_1250739_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 514.0
WLSH2_k127_1250739_9 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 509.0
WLSH2_k127_1507679_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.449e-231 725.0
WLSH2_k127_1507679_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 9.195e-210 663.0
WLSH2_k127_1507679_2 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000000000000009103 153.0
WLSH2_k127_161728_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 366.0
WLSH2_k127_161728_1 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000001667 261.0
WLSH2_k127_161728_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000004512 212.0
WLSH2_k127_161728_3 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000004931 109.0
WLSH2_k127_161728_4 - - - - 0.00000000000000000000001102 104.0
WLSH2_k127_161728_5 - - - - 0.000000000005812 73.0
WLSH2_k127_1647117_0 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 421.0
WLSH2_k127_1647117_1 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 370.0
WLSH2_k127_1647117_10 Belongs to the pirin family K06911 - - 0.00000000000000000000000000006888 117.0
WLSH2_k127_1647117_2 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 344.0
WLSH2_k127_1647117_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001869 268.0
WLSH2_k127_1647117_4 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000001703 234.0
WLSH2_k127_1647117_5 Cytochrome B561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000005676 218.0
WLSH2_k127_1647117_6 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000003399 188.0
WLSH2_k127_1647117_7 Molybdopterin binding - - - 0.00000000000000000000000000000000000000000000001173 174.0
WLSH2_k127_1647117_8 YceI-like domain - - - 0.0000000000000000000000000000000000000000000008851 175.0
WLSH2_k127_1647117_9 Outer Membrane Lipoprotein K07285 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802 - 0.0000000000000000000000000000000003615 145.0
WLSH2_k127_1672116_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.213e-234 745.0
WLSH2_k127_1672116_1 Inner membrane protein PRK11099 K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000222 287.0
WLSH2_k127_1672116_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001885 253.0
WLSH2_k127_1672116_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000002835 219.0
WLSH2_k127_1672116_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000002703 156.0
WLSH2_k127_1693298_0 electron transport coupled proton transport - - - 5.763e-290 895.0
WLSH2_k127_1693298_1 Outer membrane usher protein K07347 - - 4.504e-248 788.0
WLSH2_k127_1693298_10 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000685 269.0
WLSH2_k127_1693298_11 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000004347 243.0
WLSH2_k127_1693298_12 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000000000000000000000007284 239.0
WLSH2_k127_1693298_13 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.0000000000000000000000000000000000000000000000000000000000000001268 233.0
WLSH2_k127_1693298_14 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000001005 220.0
WLSH2_k127_1693298_15 Competence protein - - - 0.000000000000000000000000000000000000000000000000000000000001367 217.0
WLSH2_k127_1693298_16 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.0000000000000000000000000000000000000000000000000000006428 200.0
WLSH2_k127_1693298_17 Spore Coat Protein U domain - - - 0.0000000000000000000000000000000000000000003801 171.0
WLSH2_k127_1693298_18 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000003264 158.0
WLSH2_k127_1693298_19 regulatory protein, arsR - - - 0.00000000000000000000000000000000002056 138.0
WLSH2_k127_1693298_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 3.974e-230 722.0
WLSH2_k127_1693298_20 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000001083 134.0
WLSH2_k127_1693298_21 signal sequence binding - - - 0.000000000000000000000000000000001563 146.0
WLSH2_k127_1693298_22 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000002019 122.0
WLSH2_k127_1693298_23 Rhodanese Homology Domain - - - 0.0000000000000000000000000004315 117.0
WLSH2_k127_1693298_24 Spore Coat Protein U domain - - - 0.00000000000000003155 89.0
WLSH2_k127_1693298_26 Electron transport protein SCO1 SenC K07152 - - 0.00000001305 58.0
WLSH2_k127_1693298_27 Outer membrane usher protein K07347 - - 0.0000006466 52.0
WLSH2_k127_1693298_28 Spore Coat Protein U domain - - - 0.00001534 56.0
WLSH2_k127_1693298_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 473.0
WLSH2_k127_1693298_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 465.0
WLSH2_k127_1693298_5 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 367.0
WLSH2_k127_1693298_6 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 365.0
WLSH2_k127_1693298_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 351.0
WLSH2_k127_1693298_8 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 324.0
WLSH2_k127_1693298_9 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002249 276.0
WLSH2_k127_1733890_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.337e-256 803.0
WLSH2_k127_1733890_1 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 425.0
WLSH2_k127_1733890_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 352.0
WLSH2_k127_1733890_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000079 257.0
WLSH2_k127_1733890_4 Protein of unknown function (DUF2782) - - - 0.00000000000000000006133 96.0
WLSH2_k127_1733890_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000002526 75.0
WLSH2_k127_1733890_6 - - - - 0.00000005433 63.0
WLSH2_k127_1734889_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1912.0
WLSH2_k127_1734889_1 Transport of potassium into the cell K03549 - - 2.321e-286 892.0
WLSH2_k127_1734889_10 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 347.0
WLSH2_k127_1734889_11 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 310.0
WLSH2_k127_1734889_12 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 300.0
WLSH2_k127_1734889_13 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 306.0
WLSH2_k127_1734889_14 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005475 252.0
WLSH2_k127_1734889_15 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001116 258.0
WLSH2_k127_1734889_16 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000007959 237.0
WLSH2_k127_1734889_17 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001226 217.0
WLSH2_k127_1734889_18 NlpB/DapX lipoprotein K07287 - - 0.000000000000000000000000000000000000000000000000000002435 206.0
WLSH2_k127_1734889_19 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000001031 180.0
WLSH2_k127_1734889_2 PFAM PhoH family protein K07175 - - 1.335e-204 645.0
WLSH2_k127_1734889_20 long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000001113 176.0
WLSH2_k127_1734889_21 - - - - 0.00000000000000000000000000000000000000001049 157.0
WLSH2_k127_1734889_22 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000000000004042 154.0
WLSH2_k127_1734889_23 Sulfurtransferase TusA K04085 - - 0.00000000000000000000000000000005919 126.0
WLSH2_k127_1734889_24 Rhodanese Homology Domain - - - 0.000000000000000000000000000001427 124.0
WLSH2_k127_1734889_25 - - - - 0.0000000000000000000000000000401 121.0
WLSH2_k127_1734889_26 Cytochrome C oxidase, cbb3-type, subunit III K17223 - - 0.00000000000000000000000001573 113.0
WLSH2_k127_1734889_27 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000208 108.0
WLSH2_k127_1734889_28 Protein of unknown function (DUF2892) - - - 0.00000000000000000000653 94.0
WLSH2_k127_1734889_29 Domain of unknown function DUF302 - - - 0.000000002738 68.0
WLSH2_k127_1734889_3 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 605.0
WLSH2_k127_1734889_30 Sulfur oxidation protein SoxY K17226 - - 0.000008339 49.0
WLSH2_k127_1734889_4 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 565.0
WLSH2_k127_1734889_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 412.0
WLSH2_k127_1734889_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 414.0
WLSH2_k127_1734889_7 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 383.0
WLSH2_k127_1734889_8 Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 349.0
WLSH2_k127_1734889_9 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 347.0
WLSH2_k127_1761315_0 Dynamin family - - - 2.671e-218 695.0
WLSH2_k127_1761315_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 467.0
WLSH2_k127_1761315_10 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000003845 205.0
WLSH2_k127_1761315_11 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000006281 198.0
WLSH2_k127_1761315_12 HemY domain protein K02498 - - 0.0000000000000000000000000000000000000000000000002618 188.0
WLSH2_k127_1761315_13 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000004365 143.0
WLSH2_k127_1761315_14 HET domain-containing protein - - - 0.00000000000000000000000000000005429 136.0
WLSH2_k127_1761315_15 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000001395 109.0
WLSH2_k127_1761315_2 PFAM ABC-type uncharacterised transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 415.0
WLSH2_k127_1761315_3 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 366.0
WLSH2_k127_1761315_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 351.0
WLSH2_k127_1761315_5 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 343.0
WLSH2_k127_1761315_6 Protein of unknown function (DUF455) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 310.0
WLSH2_k127_1761315_7 SMART Metal-dependent phosphohydrolase, HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 300.0
WLSH2_k127_1761315_8 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005783 276.0
WLSH2_k127_1761315_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000254 214.0
WLSH2_k127_1782636_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 600.0
WLSH2_k127_1782636_1 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004439 248.0
WLSH2_k127_1782636_11 Kinase D-interacting substrate of K12460 GO:0000186,GO:0001932,GO:0001934,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005829,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007399,GO:0008150,GO:0009719,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010720,GO:0010975,GO:0010976,GO:0012505,GO:0019207,GO:0019220,GO:0019222,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022008,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030165,GO:0030234,GO:0031323,GO:0031325,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031410,GO:0031982,GO:0032147,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032991,GO:0033674,GO:0038179,GO:0038180,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043549,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0051716,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0065007,GO:0065009,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071900,GO:0071902,GO:0080090,GO:0097708,GO:0098772,GO:0120035,GO:1902531,GO:1902533,GO:1990089,GO:1990090,GO:2000026 - 0.00000001396 65.0
WLSH2_k127_1782636_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005253 244.0
WLSH2_k127_1782636_3 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000703 215.0
WLSH2_k127_1782636_4 PFAM DGPFAETKE family protein - - - 0.00000000000000000000000000000000000000000000000000000000006721 207.0
WLSH2_k127_1782636_5 Protein conserved in bacteria K04750 - - 0.000000000000000000000000000000000000000000000000000006648 192.0
WLSH2_k127_1782636_6 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000001409 185.0
WLSH2_k127_1782636_7 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000003966 144.0
WLSH2_k127_1782636_8 YCII-related domain - - - 0.000000000000000000000000000000001073 135.0
WLSH2_k127_1782636_9 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000007194 131.0
WLSH2_k127_1852343_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.122e-291 913.0
WLSH2_k127_1852343_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 7.372e-254 790.0
WLSH2_k127_1852343_10 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 315.0
WLSH2_k127_1852343_11 acid phosphatase activity K01179,K21449 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 293.0
WLSH2_k127_1852343_12 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002261 284.0
WLSH2_k127_1852343_13 PKHD-type hydroxylase K07336 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000316 276.0
WLSH2_k127_1852343_14 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006059 254.0
WLSH2_k127_1852343_15 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000000000000000000000000000000000004431 210.0
WLSH2_k127_1852343_16 SelR domain - - - 0.0000000000000000000000000000000000000000000000000000000001564 205.0
WLSH2_k127_1852343_17 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000007187 181.0
WLSH2_k127_1852343_18 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000007824 178.0
WLSH2_k127_1852343_19 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000258 175.0
WLSH2_k127_1852343_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 1.205e-205 646.0
WLSH2_k127_1852343_20 - - - - 0.000000000000000000000000000000000000000001009 163.0
WLSH2_k127_1852343_21 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000004341 132.0
WLSH2_k127_1852343_22 - - - - 0.000000000000000000000000000000006681 135.0
WLSH2_k127_1852343_23 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000000000000000006869 129.0
WLSH2_k127_1852343_24 - - - - 0.000000000000000000000000000002551 129.0
WLSH2_k127_1852343_26 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000145 69.0
WLSH2_k127_1852343_27 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000004551 55.0
WLSH2_k127_1852343_28 membrane transporter protein K07090 - - 0.00001081 55.0
WLSH2_k127_1852343_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.041e-198 627.0
WLSH2_k127_1852343_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 533.0
WLSH2_k127_1852343_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 473.0
WLSH2_k127_1852343_6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 409.0
WLSH2_k127_1852343_7 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 369.0
WLSH2_k127_1852343_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 347.0
WLSH2_k127_1852343_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 343.0
WLSH2_k127_1941946_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 614.0
WLSH2_k127_1941946_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 479.0
WLSH2_k127_1941946_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 387.0
WLSH2_k127_1941946_3 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 361.0
WLSH2_k127_1941946_4 protein required for cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000009322 197.0
WLSH2_k127_1941946_5 Invasion gene expression up-regulator SirB - - - 0.000000000000000001621 87.0
WLSH2_k127_2008683_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1362.0
WLSH2_k127_2008683_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 382.0
WLSH2_k127_2008683_2 COG0530 Ca2 Na antiporter K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000005978 242.0
WLSH2_k127_2008683_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000004145 203.0
WLSH2_k127_2008683_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000007512 55.0
WLSH2_k127_2154176_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 552.0
WLSH2_k127_2154176_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 519.0
WLSH2_k127_2154176_2 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.00000000000000002505 86.0
WLSH2_k127_2154176_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.0000000000001187 71.0
WLSH2_k127_215450_0 COG1032 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 524.0
WLSH2_k127_215450_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 494.0
WLSH2_k127_2290670_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1349.0
WLSH2_k127_2290670_1 ATP-dependent helicase K03579 - 3.6.4.13 2.282e-319 997.0
WLSH2_k127_2290670_10 domain, Protein - - - 0.000000000000000000000000000000000000000000000000001534 203.0
WLSH2_k127_2290670_11 methyltransferase activity - - - 0.0000000000000000000000000000005923 130.0
WLSH2_k127_2290670_12 protein kinase activity - - - 0.00000000000000000000000000782 121.0
WLSH2_k127_2290670_13 Subtilase family - - - 0.0000000000000005663 92.0
WLSH2_k127_2290670_15 extracellular matrix structural constituent - - - 0.00000000000008656 85.0
WLSH2_k127_2290670_16 Helicase K03579 - 3.6.4.13 0.0000000000003949 78.0
WLSH2_k127_2290670_17 Belongs to the SlyX family K03745 - - 0.0000000000009902 70.0
WLSH2_k127_2290670_18 hydratase K02509 - - 0.00000001102 66.0
WLSH2_k127_2290670_2 PFAM ABC transporter K06158 - - 3.188e-200 636.0
WLSH2_k127_2290670_3 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 414.0
WLSH2_k127_2290670_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 352.0
WLSH2_k127_2290670_5 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 333.0
WLSH2_k127_2290670_6 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000139 265.0
WLSH2_k127_2290670_7 Putative diguanylate phosphodiesterase K21025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001835 286.0
WLSH2_k127_2290670_8 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000001943 226.0
WLSH2_k127_2290670_9 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000006003 215.0
WLSH2_k127_2326965_0 Twin-arginine translocation pathway signal sequence - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 455.0
WLSH2_k127_2326965_1 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 393.0
WLSH2_k127_2326965_2 PFAM Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000296 285.0
WLSH2_k127_2326965_3 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000006049 219.0
WLSH2_k127_236106_0 PFAM FAD linked oxidase domain protein K03777 - 1.1.5.12 5.305e-197 627.0
WLSH2_k127_236106_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 2.574e-194 625.0
WLSH2_k127_236106_10 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.0000000000008881 68.0
WLSH2_k127_236106_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005219 282.0
WLSH2_k127_236106_3 Cytochrome C1 family K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001354 282.0
WLSH2_k127_236106_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000007578 250.0
WLSH2_k127_236106_5 PFAM Glutathione S-transferase, N-terminal K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005158 245.0
WLSH2_k127_236106_6 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001559 232.0
WLSH2_k127_236106_7 BON domain - - - 0.0000000000000000000000000000000000000000000004271 173.0
WLSH2_k127_236106_8 stringent starvation protein b K03600 - - 0.0000000000000000000000000000000000006837 143.0
WLSH2_k127_236106_9 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000001493 136.0
WLSH2_k127_2543029_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 569.0
WLSH2_k127_2543029_1 Belongs to the TtcA family K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 317.0
WLSH2_k127_2543029_2 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005078 281.0
WLSH2_k127_2543029_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000003022 216.0
WLSH2_k127_2543029_4 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000004987 169.0
WLSH2_k127_2630535_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 471.0
WLSH2_k127_2630535_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000000003198 145.0
WLSH2_k127_2630535_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000000000000000000000009748 142.0
WLSH2_k127_2630535_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000044 136.0
WLSH2_k127_2645533_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1089.0
WLSH2_k127_2645533_1 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 3.282e-245 796.0
WLSH2_k127_2645533_2 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 409.0
WLSH2_k127_2645533_3 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 356.0
WLSH2_k127_2645533_4 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 338.0
WLSH2_k127_2645533_5 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 0.000000000000000000000000006602 113.0
WLSH2_k127_2645533_6 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000001054 56.0
WLSH2_k127_2755548_0 inner membrane component K02011 - - 4.976e-244 765.0
WLSH2_k127_2755548_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 6.594e-204 641.0
WLSH2_k127_2755548_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 479.0
WLSH2_k127_2755548_3 Biotin and Thiamin Synthesis associated domain K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 476.0
WLSH2_k127_2755548_4 extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 433.0
WLSH2_k127_2755548_5 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000000007364 239.0
WLSH2_k127_2755548_6 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000001555 217.0
WLSH2_k127_2755548_7 transcriptional regulator K01420 - - 0.0000000007448 61.0
WLSH2_k127_2758764_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.233e-260 808.0
WLSH2_k127_2758764_1 Sodium:sulfate symporter transmembrane region - - - 1.028e-252 788.0
WLSH2_k127_2758764_10 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 396.0
WLSH2_k127_2758764_11 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 402.0
WLSH2_k127_2758764_12 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 398.0
WLSH2_k127_2758764_13 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 376.0
WLSH2_k127_2758764_14 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 353.0
WLSH2_k127_2758764_15 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 316.0
WLSH2_k127_2758764_16 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 314.0
WLSH2_k127_2758764_17 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 289.0
WLSH2_k127_2758764_18 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000002612 279.0
WLSH2_k127_2758764_19 Phosphoribosyl-ATP pyrophosphohydrolase - - - 0.00000000000000000000000000000000000000000002069 164.0
WLSH2_k127_2758764_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 3.307e-208 670.0
WLSH2_k127_2758764_20 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000001105 170.0
WLSH2_k127_2758764_21 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000183 162.0
WLSH2_k127_2758764_22 Transcriptional regulator crp fnr family K10914 - - 0.0000000000000000000000000000000000000006833 158.0
WLSH2_k127_2758764_23 sulfur carrier activity K04085 - - 0.0000000000000000000000000002777 115.0
WLSH2_k127_2758764_3 response regulator K07712 - - 3.942e-203 644.0
WLSH2_k127_2758764_4 - - - - 7.531e-200 626.0
WLSH2_k127_2758764_5 PFAM tRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 524.0
WLSH2_k127_2758764_6 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 507.0
WLSH2_k127_2758764_7 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 504.0
WLSH2_k127_2758764_8 PFAM sulfotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 431.0
WLSH2_k127_2758764_9 signal transduction histidine kinase K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 406.0
WLSH2_k127_2774506_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1071.0
WLSH2_k127_2774506_1 EAL domain - - - 9.572e-228 744.0
WLSH2_k127_2774506_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000244 125.0
WLSH2_k127_2774506_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 589.0
WLSH2_k127_2774506_3 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 467.0
WLSH2_k127_2774506_4 type I secretion outer membrane protein, TolC K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 387.0
WLSH2_k127_2774506_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006908 243.0
WLSH2_k127_2774506_6 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000000001277 207.0
WLSH2_k127_2774506_7 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000008922 169.0
WLSH2_k127_2774506_8 Alkylmercury lyase - - - 0.000000000000000000000000000000000000000004326 165.0
WLSH2_k127_2774506_9 helix_turn_helix, mercury resistance K08365 - - 0.00000000000000000000000000000002502 131.0
WLSH2_k127_2801697_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.116e-315 978.0
WLSH2_k127_2801697_1 O-methyltransferase activity - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 564.0
WLSH2_k127_2801697_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 332.0
WLSH2_k127_2801697_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009321 261.0
WLSH2_k127_2801697_4 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000007733 199.0
WLSH2_k127_2801697_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000001046 152.0
WLSH2_k127_2801697_7 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000004318 134.0
WLSH2_k127_2801697_8 protein kinase activity - - - 0.00000000000000005542 92.0
WLSH2_k127_2910485_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.647e-271 846.0
WLSH2_k127_2910485_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 392.0
WLSH2_k127_2910485_2 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 382.0
WLSH2_k127_2910485_3 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004238 245.0
WLSH2_k127_2922820_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1098.0
WLSH2_k127_2922820_1 - - - - 0.000000000000000000000000001267 113.0
WLSH2_k127_2953675_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 6.58e-303 937.0
WLSH2_k127_2953675_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 524.0
WLSH2_k127_2953675_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 504.0
WLSH2_k127_2953675_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 438.0
WLSH2_k127_2953675_4 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 298.0
WLSH2_k127_2953675_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001782 273.0
WLSH2_k127_2953675_6 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000006359 260.0
WLSH2_k127_2966262_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1046.0
WLSH2_k127_2966262_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000003349 96.0
WLSH2_k127_2966262_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000009854 66.0
WLSH2_k127_3029579_0 cell division protein K03466 - - 7.069e-208 654.0
WLSH2_k127_3029579_1 AAA ATPase, central domain protein K07478 - - 2.636e-199 631.0
WLSH2_k127_3029579_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000001128 188.0
WLSH2_k127_3029579_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000002395 118.0
WLSH2_k127_3061849_0 Tetratricopeptide repeat - - - 3.19e-308 971.0
WLSH2_k127_3061849_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 553.0
WLSH2_k127_3061849_2 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004708 269.0
WLSH2_k127_3061849_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000004645 165.0
WLSH2_k127_3061849_4 - - - - 0.00000000000000000000000003634 115.0
WLSH2_k127_3061849_5 Biopolymer transport protein ExbD/TolR - - - 0.000000000000002484 78.0
WLSH2_k127_3069288_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 3.265e-196 621.0
WLSH2_k127_3069288_1 in Yersinia the HmsR protein is an inner membrane protein K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 494.0
WLSH2_k127_3069288_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 421.0
WLSH2_k127_3069288_3 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 287.0
WLSH2_k127_3069288_4 response regulator receiver K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000003059 241.0
WLSH2_k127_3069288_5 Hypothetical glycosyl hydrolase family 13 K11931 - - 0.00000000000000000000000000000000000000000000000000000000000001324 235.0
WLSH2_k127_3069288_6 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000005312 134.0
WLSH2_k127_3069288_7 Tetratricopeptide repeat K11935 - - 0.0000000000002577 82.0
WLSH2_k127_3104141_0 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145 2.7.13.3 7.484e-220 701.0
WLSH2_k127_3104141_1 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 428.0
WLSH2_k127_3104141_2 PFAM Chemotaxis methyl-accepting receptor, signalling - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 323.0
WLSH2_k127_3104141_3 response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000000000000003536 193.0
WLSH2_k127_3104141_4 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000005808 196.0
WLSH2_k127_3104141_5 antisigma factor binding K03409,K05946 - 2.4.1.187 0.0000004509 57.0
WLSH2_k127_325455_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 4.249e-253 801.0
WLSH2_k127_325455_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 338.0
WLSH2_k127_325455_2 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 297.0
WLSH2_k127_325455_3 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004276 285.0
WLSH2_k127_325455_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000005995 227.0
WLSH2_k127_325455_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000001611 226.0
WLSH2_k127_325455_6 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000005984 208.0
WLSH2_k127_325455_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000001626 99.0
WLSH2_k127_325455_8 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000001759 73.0
WLSH2_k127_3395371_0 Outer membrane protein beta-barrel family - - - 1.854e-259 818.0
WLSH2_k127_3395371_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 475.0
WLSH2_k127_3395371_10 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000759 197.0
WLSH2_k127_3395371_11 Protein of unknown function (DUF489) K07153 - - 0.00000000000000000000000000000000000000000000000008551 184.0
WLSH2_k127_3395371_12 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000005285 171.0
WLSH2_k127_3395371_13 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000000000000003956 136.0
WLSH2_k127_3395371_14 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000006318 119.0
WLSH2_k127_3395371_15 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000004449 76.0
WLSH2_k127_3395371_16 Protein of unknown function (DUF1375) - - - 0.0000006494 56.0
WLSH2_k127_3395371_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 428.0
WLSH2_k127_3395371_3 Signal transduction histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 383.0
WLSH2_k127_3395371_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 387.0
WLSH2_k127_3395371_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 366.0
WLSH2_k127_3395371_6 CBS-domain-containing membrane protein K07168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 361.0
WLSH2_k127_3395371_7 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 328.0
WLSH2_k127_3395371_8 response regulator K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000003326 238.0
WLSH2_k127_3395371_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000009454 199.0
WLSH2_k127_3481295_0 Aconitase C-terminal domain K01681 - 4.2.1.3 1.769e-304 951.0
WLSH2_k127_3481295_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.092e-253 798.0
WLSH2_k127_3481295_10 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 301.0
WLSH2_k127_3481295_11 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000004067 273.0
WLSH2_k127_3481295_12 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001906 242.0
WLSH2_k127_3481295_13 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000006443 224.0
WLSH2_k127_3481295_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000005638 205.0
WLSH2_k127_3481295_15 Universal stress protein - - - 0.000000000000000000000000000000000000000001652 160.0
WLSH2_k127_3481295_16 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000003895 167.0
WLSH2_k127_3481295_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.026e-238 749.0
WLSH2_k127_3481295_20 dehydrogenase e1 component K00161,K11381 - 1.2.4.1,1.2.4.4 0.0003638 46.0
WLSH2_k127_3481295_21 - - - - 0.0008741 42.0
WLSH2_k127_3481295_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 579.0
WLSH2_k127_3481295_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 495.0
WLSH2_k127_3481295_5 TIGRFAM malate synthase A K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 380.0
WLSH2_k127_3481295_6 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 378.0
WLSH2_k127_3481295_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 360.0
WLSH2_k127_3481295_8 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 358.0
WLSH2_k127_3481295_9 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 301.0
WLSH2_k127_3516921_0 FtsX-like permease family K02004 - - 8.541e-228 728.0
WLSH2_k127_3516921_1 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 355.0
WLSH2_k127_3516921_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 294.0
WLSH2_k127_3516921_3 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000004377 237.0
WLSH2_k127_3516921_4 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000372 179.0
WLSH2_k127_3516921_5 Zinc-ribbon containing domain - - - 0.0000000000006545 78.0
WLSH2_k127_3527646_0 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1069.0
WLSH2_k127_3527646_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 7.362e-300 944.0
WLSH2_k127_3527646_10 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 469.0
WLSH2_k127_3527646_11 phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 432.0
WLSH2_k127_3527646_12 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 391.0
WLSH2_k127_3527646_13 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 372.0
WLSH2_k127_3527646_14 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 346.0
WLSH2_k127_3527646_15 ZIP Zinc transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 319.0
WLSH2_k127_3527646_16 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 327.0
WLSH2_k127_3527646_17 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 306.0
WLSH2_k127_3527646_18 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001243 280.0
WLSH2_k127_3527646_19 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001735 271.0
WLSH2_k127_3527646_2 PFAM Glycoside hydrolase 15-related K01178 - 3.2.1.3 2.479e-278 865.0
WLSH2_k127_3527646_20 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000001738 269.0
WLSH2_k127_3527646_21 pseudouridine synthase activity K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000002628 269.0
WLSH2_k127_3527646_22 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000006367 245.0
WLSH2_k127_3527646_23 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000001263 253.0
WLSH2_k127_3527646_24 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006808,GO:0008144,GO:0008150,GO:0009889,GO:0010565,GO:0017076,GO:0019216,GO:0019217,GO:0019222,GO:0030234,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042304,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0046890,GO:0050789,GO:0050790,GO:0050794,GO:0062012,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:0097367,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000001987 203.0
WLSH2_k127_3527646_25 Bacterial type II and III secretion system protein - - - 0.0000000000000000000000000000000000000000000000000002311 196.0
WLSH2_k127_3527646_26 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000007133 194.0
WLSH2_k127_3527646_27 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000001085 186.0
WLSH2_k127_3527646_28 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000004873 183.0
WLSH2_k127_3527646_29 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000001848 151.0
WLSH2_k127_3527646_3 Belongs to the IlvD Edd family - - - 1.276e-235 734.0
WLSH2_k127_3527646_30 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000002755 155.0
WLSH2_k127_3527646_31 - - - - 0.00000000000000000000000000000000000004226 150.0
WLSH2_k127_3527646_32 aminopeptidase activity - - - 0.00000000000000000000000000000000003853 149.0
WLSH2_k127_3527646_33 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000005301 137.0
WLSH2_k127_3527646_34 PFAM NLP P60 protein - - - 0.00000000000000000000000000000001014 132.0
WLSH2_k127_3527646_35 - - - - 0.00000000000000000000000006704 110.0
WLSH2_k127_3527646_36 Cold shock protein K03704 - - 0.00000000000000000000000007054 107.0
WLSH2_k127_3527646_37 AntiSigma factor - - - 0.000000000000000000000000229 115.0
WLSH2_k127_3527646_38 protein acetylation - - - 0.00000003465 61.0
WLSH2_k127_3527646_39 - - - - 0.0000002897 59.0
WLSH2_k127_3527646_4 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114 1.1.1.42 2.112e-218 685.0
WLSH2_k127_3527646_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 - 6.3.1.5,6.3.5.1 2.091e-211 669.0
WLSH2_k127_3527646_6 Adenylosuccinate lyase C-terminal K01756 - 4.3.2.2 2.646e-206 651.0
WLSH2_k127_3527646_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 513.0
WLSH2_k127_3527646_8 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 497.0
WLSH2_k127_3527646_9 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 481.0
WLSH2_k127_3657776_0 cation transport ATPase K17686 - 3.6.3.54 2.063e-266 839.0
WLSH2_k127_3657776_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.106e-266 829.0
WLSH2_k127_3657776_10 Cytochrome c, class I - - - 0.000000000002052 70.0
WLSH2_k127_3657776_12 Domain of unknown function (DUF3330) - - - 0.000004229 59.0
WLSH2_k127_3657776_13 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00004342 49.0
WLSH2_k127_3657776_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 509.0
WLSH2_k127_3657776_3 protein conserved in bacteria K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 387.0
WLSH2_k127_3657776_5 Amine oxidase, flavin-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000001248 239.0
WLSH2_k127_3657776_6 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000003283 208.0
WLSH2_k127_3657776_7 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000000000000000002045 134.0
WLSH2_k127_3657776_8 sulfur carrier activity - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0033554,GO:0042592,GO:0048878,GO:0050896,GO:0051716,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000004607 123.0
WLSH2_k127_3657776_9 protein histidine kinase activity K06375 - - 0.00000000000000000000000000002523 126.0
WLSH2_k127_3729098_0 Beta-Casp domain K07576 - - 1.438e-213 672.0
WLSH2_k127_3729098_1 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 2.468e-198 644.0
WLSH2_k127_3729098_2 Glycosyl transferases group 1 K13057 - 2.4.1.245 4.091e-196 618.0
WLSH2_k127_3729098_3 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 605.0
WLSH2_k127_3729098_4 mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 371.0
WLSH2_k127_3729098_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003075 261.0
WLSH2_k127_3729098_6 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000008605 242.0
WLSH2_k127_3729098_7 - - - - 0.000000000000000000000000000000000000000004646 158.0
WLSH2_k127_3768366_0 Bifunctional transglycosylase second domain K05365 - 2.4.1.129,3.4.16.4 3.116e-297 931.0
WLSH2_k127_3768366_1 Cytochrome D1 heme domain - - - 2.819e-240 751.0
WLSH2_k127_3768366_10 heme biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
WLSH2_k127_3768366_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000002223 219.0
WLSH2_k127_3768366_12 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000003839 218.0
WLSH2_k127_3768366_13 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 GO:0006139,GO:0006351,GO:0006352,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010604,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031437,GO:0031439,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903311,GO:1903313,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000002802 214.0
WLSH2_k127_3768366_14 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000002574 198.0
WLSH2_k127_3768366_15 SseB protein N-terminal domain - - - 0.000000000000000000000000000000000000000000883 160.0
WLSH2_k127_3768366_16 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000001188 147.0
WLSH2_k127_3768366_17 PLD-like domain K06131 - - 0.00000000000000000000000000000000004004 138.0
WLSH2_k127_3768366_18 Chalcone isomerase-like - - - 0.0000000000000000000000000000000005407 138.0
WLSH2_k127_3768366_19 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000000001565 121.0
WLSH2_k127_3768366_2 fad dependent oxidoreductase K07137 - - 7.097e-232 728.0
WLSH2_k127_3768366_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000121 116.0
WLSH2_k127_3768366_21 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07226 - - 0.00000000000000000000000000375 117.0
WLSH2_k127_3768366_22 COG2010 Cytochrome c, mono- and diheme variants K19344 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000001275 113.0
WLSH2_k127_3768366_3 4Fe-4S single cluster domain - - - 3.001e-217 678.0
WLSH2_k127_3768366_4 cytochrome d1, heme region K19345 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 567.0
WLSH2_k127_3768366_5 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 481.0
WLSH2_k127_3768366_6 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006566 327.0
WLSH2_k127_3768366_7 serine threonine protein kinase K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001992 280.0
WLSH2_k127_3768366_8 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 256.0
WLSH2_k127_3768366_9 transcriptional regulator AsnC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002348 252.0
WLSH2_k127_3778168_0 PFAM Carbamoyl-phosphate synthase L chain K01961 - 6.3.4.14,6.4.1.2 2.325e-237 739.0
WLSH2_k127_3778168_1 bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 6.984e-233 732.0
WLSH2_k127_3778168_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
WLSH2_k127_3778168_11 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000004202 204.0
WLSH2_k127_3778168_12 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000001492 188.0
WLSH2_k127_3778168_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000001211 188.0
WLSH2_k127_3778168_14 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000001764 150.0
WLSH2_k127_3778168_15 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000001204 128.0
WLSH2_k127_3778168_16 Bacterial regulatory protein, Fis family K03557 - - 0.00000000000000000000006988 100.0
WLSH2_k127_3778168_17 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.0000000000000000000265 93.0
WLSH2_k127_3778168_18 Iron permease FTR1 K07243 - - 0.000004154 53.0
WLSH2_k127_3778168_2 Belongs to the GARS family K01945 - 6.3.4.13 5.949e-198 624.0
WLSH2_k127_3778168_3 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 580.0
WLSH2_k127_3778168_4 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 533.0
WLSH2_k127_3778168_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 480.0
WLSH2_k127_3778168_6 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 425.0
WLSH2_k127_3778168_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 334.0
WLSH2_k127_3778168_8 Methylates ribosomal protein L11 K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 305.0
WLSH2_k127_3778168_9 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000609 234.0
WLSH2_k127_3780303_0 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 510.0
WLSH2_k127_3780303_1 Belongs to the phosphatidylserine decarboxylase family K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 430.0
WLSH2_k127_3780303_2 Prolipoprotein diacylglyceryl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 348.0
WLSH2_k127_3796541_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.321e-300 937.0
WLSH2_k127_3796541_1 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 548.0
WLSH2_k127_3796541_10 Thioredoxin domain - - - 0.0000000000000000000000000000000003321 132.0
WLSH2_k127_3796541_11 cytochrome - - - 0.00000000000000000000000000004946 120.0
WLSH2_k127_3796541_12 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000006107 108.0
WLSH2_k127_3796541_2 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 528.0
WLSH2_k127_3796541_3 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 465.0
WLSH2_k127_3796541_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 453.0
WLSH2_k127_3796541_5 Phosphate transport system permease protein K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 446.0
WLSH2_k127_3796541_6 AAA domain, putative AbiEii toxin, Type IV TA system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008053 428.0
WLSH2_k127_3796541_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 315.0
WLSH2_k127_3796541_8 low molecular weight K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000006977 233.0
WLSH2_k127_3796541_9 PFAM CHAD domain containing protein - - - 0.00000000000000000000000000000000000005028 154.0
WLSH2_k127_3854450_0 von Willebrand factor (vWF) type A domain - - - 0.0 1297.0
WLSH2_k127_3854450_1 BMC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001698 252.0
WLSH2_k127_3871136_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008236 271.0
WLSH2_k127_3871136_1 Belongs to the peptidase S11 family K07262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001172 252.0
WLSH2_k127_3871136_2 Protein of unknown function (DUF3775) - - - 0.00000000000000000000000000000000000000000000000000118 185.0
WLSH2_k127_3871136_3 - - - - 0.000000000000000000000000000000000000003095 150.0
WLSH2_k127_3914795_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1047.0
WLSH2_k127_3914795_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 - 1.5e-292 910.0
WLSH2_k127_3914795_10 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001665 260.0
WLSH2_k127_3914795_11 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001978 249.0
WLSH2_k127_3914795_12 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000404 247.0
WLSH2_k127_3914795_13 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000000000000008417 215.0
WLSH2_k127_3914795_14 PFAM Di-haem cytochrome c - - - 0.00000000000000000000000000000000000000000000000001033 184.0
WLSH2_k127_3914795_15 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000000000000000000004511 170.0
WLSH2_k127_3914795_16 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000000000004675 161.0
WLSH2_k127_3914795_2 Cysteine-rich domain - - - 2.469e-243 757.0
WLSH2_k127_3914795_3 type II secretion system protein E K02454,K02504,K02652,K12276 - - 3.267e-213 675.0
WLSH2_k127_3914795_4 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 595.0
WLSH2_k127_3914795_5 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 452.0
WLSH2_k127_3914795_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 388.0
WLSH2_k127_3914795_7 CoA-binding domain protein K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 330.0
WLSH2_k127_3914795_8 PFAM response regulator receiver K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 308.0
WLSH2_k127_3914795_9 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007282 273.0
WLSH2_k127_3981980_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 513.0
WLSH2_k127_3981980_1 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 324.0
WLSH2_k127_3981980_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000008584 230.0
WLSH2_k127_3981980_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000006409 183.0
WLSH2_k127_3981980_4 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000000003155 163.0
WLSH2_k127_3981980_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000001522 76.0
WLSH2_k127_3990447_0 Major Facilitator - - - 3.984e-232 723.0
WLSH2_k127_3990447_1 Bacterial transcriptional activator domain - - - 6.477e-204 672.0
WLSH2_k127_3990447_10 Ribosomal protein L33 K02913 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001017 97.0
WLSH2_k127_3990447_11 Short C-terminal domain K08982 - - 0.0000000000000001204 82.0
WLSH2_k127_3990447_12 - - - - 0.000002905 53.0
WLSH2_k127_3990447_2 oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 451.0
WLSH2_k127_3990447_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 381.0
WLSH2_k127_3990447_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 306.0
WLSH2_k127_3990447_5 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003 268.0
WLSH2_k127_3990447_6 DsrE/DsrF-like family K06039 - - 0.00000000000000000000000000000000000000000000000002544 182.0
WLSH2_k127_3990447_7 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000008552 178.0
WLSH2_k127_3990447_8 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000006257 131.0
WLSH2_k127_3990447_9 DsrE/DsrF-like family K06039 - - 0.0000000000000000000000403 104.0
WLSH2_k127_4043926_0 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 294.0
WLSH2_k127_4043926_1 auxin efflux carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000004871 200.0
WLSH2_k127_4043926_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000001509 119.0
WLSH2_k127_4043926_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00004313 48.0
WLSH2_k127_4053812_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 557.0
WLSH2_k127_4053812_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 428.0
WLSH2_k127_4053812_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 396.0
WLSH2_k127_4053812_3 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000000000000000000000003427 164.0
WLSH2_k127_4053812_4 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000009018 71.0
WLSH2_k127_4053812_5 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000001309 57.0
WLSH2_k127_4144911_0 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 419.0
WLSH2_k127_4144911_1 Molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 294.0
WLSH2_k127_4144911_2 Outer Membrane Lipoprotein K07285 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802 - 0.000000000000000000000000000000000000003173 153.0
WLSH2_k127_4144911_3 Haem-degrading - - - 0.00000000000000000000000000000197 123.0
WLSH2_k127_4144911_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000007288 116.0
WLSH2_k127_4158038_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.9e-220 690.0
WLSH2_k127_4158038_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 561.0
WLSH2_k127_4158038_2 Zn-dependent protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 486.0
WLSH2_k127_4158038_3 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.000000000000000000000000000000000000000000000000000000002789 208.0
WLSH2_k127_4158038_4 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000007582 189.0
WLSH2_k127_4158038_5 nuclease - - - 0.00000000000000000000000000000000000000000000523 173.0
WLSH2_k127_4158038_6 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.00000000000000000000000000000000000000000002462 166.0
WLSH2_k127_4158038_7 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000739 120.0
WLSH2_k127_4158368_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0 1186.0
WLSH2_k127_4158368_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 562.0
WLSH2_k127_4158368_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 530.0
WLSH2_k127_4158368_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 524.0
WLSH2_k127_4158368_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 478.0
WLSH2_k127_4158368_5 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 467.0
WLSH2_k127_4158368_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 437.0
WLSH2_k127_4158368_7 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 334.0
WLSH2_k127_4158368_8 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000003608 249.0
WLSH2_k127_41629_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 537.0
WLSH2_k127_41629_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 293.0
WLSH2_k127_41629_2 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000001963 205.0
WLSH2_k127_41629_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000002531 180.0
WLSH2_k127_41629_4 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000001053 158.0
WLSH2_k127_41629_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000002022 102.0
WLSH2_k127_41629_6 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000002574 58.0
WLSH2_k127_4170566_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1247.0
WLSH2_k127_4170566_1 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002426 246.0
WLSH2_k127_4170566_2 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000006028 133.0
WLSH2_k127_4170566_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000002029 108.0
WLSH2_k127_4298094_0 Epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 380.0
WLSH2_k127_4298094_1 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 319.0
WLSH2_k127_4298094_2 Type II secretion system protein B K02451 - - 0.000000000001948 76.0
WLSH2_k127_4309406_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 429.0
WLSH2_k127_4309406_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 331.0
WLSH2_k127_4309406_2 TIGRFAM 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 302.0
WLSH2_k127_4309406_3 HIT domain - - - 0.00000000000000000000000000000000000000000000003308 173.0
WLSH2_k127_4309406_4 - - - - 0.00000000000000000000000000005574 121.0
WLSH2_k127_4309406_5 Domain of unknown function (DUF4198) - - - 0.000000000000007102 77.0
WLSH2_k127_4309406_6 Thioesterase-like superfamily - - - 0.000001416 52.0
WLSH2_k127_4326236_0 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 404.0
WLSH2_k127_4326236_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 386.0
WLSH2_k127_4376971_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 499.0
WLSH2_k127_4376971_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004742 261.0
WLSH2_k127_4376971_2 Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000002719 159.0
WLSH2_k127_4376971_3 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000462 146.0
WLSH2_k127_4376971_4 Cell envelope biogenesis protein TolA K03646 - - 0.000000000000000000000002313 113.0
WLSH2_k127_4376971_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00027 48.0
WLSH2_k127_4426667_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 7.334e-287 893.0
WLSH2_k127_4426667_1 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 415.0
WLSH2_k127_4426667_2 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 355.0
WLSH2_k127_4426667_3 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009448 283.0
WLSH2_k127_4426667_4 ABC-type phosphate transport system, periplasmic component - - - 0.0000000000000000000000000000000003913 136.0
WLSH2_k127_4426667_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000000001517 79.0
WLSH2_k127_4479107_0 Ammonium transporter K03320,K06580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 597.0
WLSH2_k127_4479107_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 551.0
WLSH2_k127_4479107_10 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002563 272.0
WLSH2_k127_4479107_11 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002102 273.0
WLSH2_k127_4479107_12 ATPase or kinase K06925 GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000001961 178.0
WLSH2_k127_4479107_13 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000002208 157.0
WLSH2_k127_4479107_14 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000153 134.0
WLSH2_k127_4479107_15 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000005391 94.0
WLSH2_k127_4479107_16 Cytochrome c - - - 0.0000000000004009 74.0
WLSH2_k127_4479107_17 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0001601 48.0
WLSH2_k127_4479107_2 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 534.0
WLSH2_k127_4479107_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 501.0
WLSH2_k127_4479107_4 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 494.0
WLSH2_k127_4479107_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 483.0
WLSH2_k127_4479107_6 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 420.0
WLSH2_k127_4479107_7 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 366.0
WLSH2_k127_4479107_8 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 343.0
WLSH2_k127_4479107_9 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 304.0
WLSH2_k127_4483288_0 Aminotransferase K01845 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 599.0
WLSH2_k127_4483288_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 486.0
WLSH2_k127_4483288_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 325.0
WLSH2_k127_4483288_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000001305 232.0
WLSH2_k127_4483288_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000524 223.0
WLSH2_k127_4483288_5 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000007547 214.0
WLSH2_k127_4483288_6 COG2863 Cytochrome c553 - - - 0.00000000000000000000000000000000000000000000000000003246 194.0
WLSH2_k127_4516823_0 Putative nucleotide-binding of sugar-metabolising enzyme - - - 1.917e-196 621.0
WLSH2_k127_4516823_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 429.0
WLSH2_k127_4516823_2 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000002922 196.0
WLSH2_k127_4587528_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 0.0 1116.0
WLSH2_k127_4587528_1 PFAM von Willebrand factor type A - - - 0.0 1103.0
WLSH2_k127_4587528_10 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 384.0
WLSH2_k127_4587528_11 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 338.0
WLSH2_k127_4587528_12 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006566 272.0
WLSH2_k127_4587528_13 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000149 233.0
WLSH2_k127_4587528_14 transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000001607 223.0
WLSH2_k127_4587528_15 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002354 227.0
WLSH2_k127_4587528_16 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000002475 215.0
WLSH2_k127_4587528_17 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000001377 213.0
WLSH2_k127_4587528_18 protein conserved in bacteria K09928 - - 0.000000000000000000000000000000000000000000000000000007493 194.0
WLSH2_k127_4587528_19 Cysteine-rich CPCC - - - 0.00000000000000000000000000000000000000000000000000003374 191.0
WLSH2_k127_4587528_2 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 3.051e-299 919.0
WLSH2_k127_4587528_20 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000001946 123.0
WLSH2_k127_4587528_21 Cupin 2, conserved barrel domain protein K21700 - - 0.0000000000000000000008003 100.0
WLSH2_k127_4587528_22 Phosphate-starvation-inducible E K13256 - - 0.000002104 50.0
WLSH2_k127_4587528_3 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 1.383e-222 693.0
WLSH2_k127_4587528_4 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 1.154e-208 651.0
WLSH2_k127_4587528_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 1.892e-200 626.0
WLSH2_k127_4587528_6 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.78e-196 623.0
WLSH2_k127_4587528_7 Hpt domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 552.0
WLSH2_k127_4587528_8 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 479.0
WLSH2_k127_4587528_9 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 471.0
WLSH2_k127_458948_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 566.0
WLSH2_k127_458948_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000001256 269.0
WLSH2_k127_458948_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000002554 245.0
WLSH2_k127_458948_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000004539 238.0
WLSH2_k127_4651870_0 Putative diguanylate phosphodiesterase - - - 4.291e-239 749.0
WLSH2_k127_4651870_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 361.0
WLSH2_k127_4651870_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 297.0
WLSH2_k127_4651870_3 PFAM ApaG domain protein K06195 - - 0.000000000000000000000000000000000000000000000000000000005584 201.0
WLSH2_k127_4722647_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2318.0
WLSH2_k127_4722647_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.944e-281 874.0
WLSH2_k127_4722647_10 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000002544 208.0
WLSH2_k127_4722647_11 PFAM Fimbrial assembly K02663 - - 0.0000000000000000000000000000000000000000000000004001 183.0
WLSH2_k127_4722647_12 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000006648 171.0
WLSH2_k127_4722647_13 pilus assembly protein PilP K02665 - - 0.0000000000000000000000000000000000000000001118 166.0
WLSH2_k127_4722647_14 - - - - 0.00000000000000000000000005882 114.0
WLSH2_k127_4722647_15 PFAM Sporulation domain protein - - - 0.00000000000000000000002112 108.0
WLSH2_k127_4722647_2 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 1.203e-251 801.0
WLSH2_k127_4722647_3 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 4.74e-236 737.0
WLSH2_k127_4722647_4 type IV pilus secretin PilQ K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 597.0
WLSH2_k127_4722647_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 560.0
WLSH2_k127_4722647_6 dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 512.0
WLSH2_k127_4722647_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 496.0
WLSH2_k127_4722647_8 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 408.0
WLSH2_k127_4722647_9 PFAM Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000004644 212.0
WLSH2_k127_4773087_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 364.0
WLSH2_k127_4773087_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 354.0
WLSH2_k127_4773087_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002057 261.0
WLSH2_k127_4773087_3 Sulphur transport K07112 - - 0.000000000000000000000000000000000000003476 155.0
WLSH2_k127_4773087_4 membrane K15977 - - 0.000000000000000000000000000000000000007922 158.0
WLSH2_k127_4773087_5 - K07112 - - 0.0000000000000000000000000000493 121.0
WLSH2_k127_4773087_7 Ankyrin repeat - - - 0.0000000006369 67.0
WLSH2_k127_4773087_8 Haem-degrading - - - 0.00055 46.0
WLSH2_k127_4881287_0 response regulator receiver K02487,K06596 - - 6.94e-282 934.0
WLSH2_k127_4881287_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 2.344e-219 688.0
WLSH2_k127_4881287_10 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000002985 258.0
WLSH2_k127_4881287_11 phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000002824 226.0
WLSH2_k127_4881287_12 TIGRFAM TonB family protein K03832 - - 0.000000000000000000000000000000000000000000000000000000000007666 218.0
WLSH2_k127_4881287_13 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000001847 186.0
WLSH2_k127_4881287_14 response regulator K02657 - - 0.000000000000000000000000000000000000000000000000002334 185.0
WLSH2_k127_4881287_15 RESPONSE REGULATOR receiver K02658 - - 0.000000000000000000000000000000000000000000005133 167.0
WLSH2_k127_4881287_16 - - - - 0.00000000000000000000000000000000000000000005393 163.0
WLSH2_k127_4881287_17 COG1651 Protein-disulfide isomerase K21990 - - 0.0000000000000000000000000000000000004704 150.0
WLSH2_k127_4881287_18 Type IV pili signal transduction protein PilI K02659 - - 0.000000000000000000000000000000002571 138.0
WLSH2_k127_4881287_19 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000003056 134.0
WLSH2_k127_4881287_2 Glutamate-cysteine ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 576.0
WLSH2_k127_4881287_20 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000001589 115.0
WLSH2_k127_4881287_21 chemotaxis signal transduction protein K06598 - - 0.00000000002074 72.0
WLSH2_k127_4881287_22 regulation of response to stimulus K13730 - - 0.000000002085 71.0
WLSH2_k127_4881287_23 Subtilase family K14645 - - 0.00001566 52.0
WLSH2_k127_4881287_3 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 481.0
WLSH2_k127_4881287_4 COG0840 Methyl-accepting chemotaxis protein K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 476.0
WLSH2_k127_4881287_5 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 391.0
WLSH2_k127_4881287_6 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 309.0
WLSH2_k127_4881287_7 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 308.0
WLSH2_k127_4881287_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 285.0
WLSH2_k127_4881287_9 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000005094 236.0
WLSH2_k127_4884348_0 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 512.0
WLSH2_k127_4884348_1 Domain of unknown function (DUF3329) K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 393.0
WLSH2_k127_4884348_2 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 332.0
WLSH2_k127_4884348_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 297.0
WLSH2_k127_4884348_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004789 259.0
WLSH2_k127_4884348_5 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000004171 186.0
WLSH2_k127_4884348_6 - - - - 0.0000000000000000000000000000000000000000000000648 173.0
WLSH2_k127_4884348_7 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000001635 172.0
WLSH2_k127_4884348_8 PFAM Bacterial regulatory protein, arsR family K03892 - - 0.0000000000000000000000000000000002479 138.0
WLSH2_k127_4884348_9 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000007803 119.0
WLSH2_k127_4911248_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 554.0
WLSH2_k127_4911248_1 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 383.0
WLSH2_k127_4911248_2 PFAM AsmA family protein K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 321.0
WLSH2_k127_4911248_3 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000002168 197.0
WLSH2_k127_4911248_4 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000004078 200.0
WLSH2_k127_4911248_5 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000001993 145.0
WLSH2_k127_4911248_6 positive regulation of type IV pilus biogenesis K07343 - - 0.0000000000000000000000000001964 119.0
WLSH2_k127_4911248_7 Resolvase - - - 0.0000008099 59.0
WLSH2_k127_4991910_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1400.0
WLSH2_k127_4991910_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1089.0
WLSH2_k127_4991910_10 Cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003597 277.0
WLSH2_k127_4991910_11 ferredoxin-type protein napF K02572 - - 0.0000000000000000000000000000000000000000005815 162.0
WLSH2_k127_4991910_12 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000001053 155.0
WLSH2_k127_4991910_13 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.0000000000000000000000000000006355 132.0
WLSH2_k127_4991910_14 cytochrome - - - 0.00000000000000000000000001326 109.0
WLSH2_k127_4991910_15 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000004519 106.0
WLSH2_k127_4991910_16 NapD protein K02570 - - 0.00000000000003361 77.0
WLSH2_k127_4991910_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 485.0
WLSH2_k127_4991910_4 HI0933-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 462.0
WLSH2_k127_4991910_5 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 402.0
WLSH2_k127_4991910_6 4Fe-4S dicluster domain K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 387.0
WLSH2_k127_4991910_7 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 330.0
WLSH2_k127_4991910_8 4Fe-4S dicluster domain K16887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 319.0
WLSH2_k127_4991910_9 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000168 285.0
WLSH2_k127_5035719_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.598e-317 993.0
WLSH2_k127_5035719_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 5.528e-301 933.0
WLSH2_k127_5035719_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 592.0
WLSH2_k127_5035719_11 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 585.0
WLSH2_k127_5035719_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 518.0
WLSH2_k127_5035719_13 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 340.0
WLSH2_k127_5035719_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 325.0
WLSH2_k127_5035719_15 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 329.0
WLSH2_k127_5035719_16 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 319.0
WLSH2_k127_5035719_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 290.0
WLSH2_k127_5035719_18 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003172 269.0
WLSH2_k127_5035719_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001199 263.0
WLSH2_k127_5035719_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 6.5e-286 891.0
WLSH2_k127_5035719_20 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001629 252.0
WLSH2_k127_5035719_21 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004541 240.0
WLSH2_k127_5035719_22 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000003572 234.0
WLSH2_k127_5035719_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000002995 213.0
WLSH2_k127_5035719_24 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000001281 181.0
WLSH2_k127_5035719_25 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000003487 175.0
WLSH2_k127_5035719_26 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000003542 125.0
WLSH2_k127_5035719_27 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000004788 118.0
WLSH2_k127_5035719_28 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000002976 116.0
WLSH2_k127_5035719_29 RNA-binding protein, YhbY family K07574 - - 0.000000000000000000000008768 104.0
WLSH2_k127_5035719_3 Belongs to the CarB family K01955 - 6.3.5.5 2.982e-280 872.0
WLSH2_k127_5035719_30 Preprotein translocase subunit SecG K03075 - - 0.00000000000000000003596 94.0
WLSH2_k127_5035719_31 Helix-turn-helix domain - - - 0.00000000000000000007464 92.0
WLSH2_k127_5035719_32 Domain of unknown function (DUF4149) - - - 0.00000000000000001204 89.0
WLSH2_k127_5035719_33 - - - - 0.000000006599 58.0
WLSH2_k127_5035719_4 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.811e-279 882.0
WLSH2_k127_5035719_5 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 5.644e-263 835.0
WLSH2_k127_5035719_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 5.31e-245 760.0
WLSH2_k127_5035719_7 NADH-quinone oxidoreductase subunit F K00335 - 1.6.5.3 2.445e-223 697.0
WLSH2_k127_5035719_8 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 6.911e-219 689.0
WLSH2_k127_5035719_9 Participates in both transcription termination and antitermination K02600 - - 8.327e-200 633.0
WLSH2_k127_5052927_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.756e-208 658.0
WLSH2_k127_5052927_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 434.0
WLSH2_k127_5052927_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001285 282.0
WLSH2_k127_5052927_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000003254 158.0
WLSH2_k127_5117302_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.691e-254 787.0
WLSH2_k127_5117302_1 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 366.0
WLSH2_k127_5117302_2 SEC-C motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 347.0
WLSH2_k127_5385228_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 486.0
WLSH2_k127_5385228_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 395.0
WLSH2_k127_5385228_10 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000001004 118.0
WLSH2_k127_5385228_11 Predicted integral membrane protein (DUF2282) - - - 0.0000000000000000000005387 97.0
WLSH2_k127_5385228_12 Integral membrane protein - - - 0.0000000000000000006587 90.0
WLSH2_k127_5385228_13 - - - - 0.000000000000000008292 85.0
WLSH2_k127_5385228_14 acr, cog1678 K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000002767 85.0
WLSH2_k127_5385228_15 PFAM RNA recognition motif - - - 0.000000004486 61.0
WLSH2_k127_5385228_16 Phospholipase lecithinase hemolysin - - - 0.000002366 57.0
WLSH2_k127_5385228_2 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 389.0
WLSH2_k127_5385228_3 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 379.0
WLSH2_k127_5385228_4 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 336.0
WLSH2_k127_5385228_5 Exonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 286.0
WLSH2_k127_5385228_6 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000004335 184.0
WLSH2_k127_5385228_7 Protein of unknown function (DUF1244) K09948 - - 0.0000000000000000000000000000000000000000000002266 173.0
WLSH2_k127_5385228_8 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000000000000004544 168.0
WLSH2_k127_5385228_9 RNA recognition motif - - - 0.000000000000000000000000000007594 121.0
WLSH2_k127_5453202_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1378.0
WLSH2_k127_5453202_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 535.0
WLSH2_k127_5453202_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000004571 189.0
WLSH2_k127_5453202_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000001676 110.0
WLSH2_k127_5453202_4 MacB-like periplasmic core domain K02004 - - 0.0000000000002497 70.0
WLSH2_k127_5463370_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 2.176e-195 625.0
WLSH2_k127_5463370_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 523.0
WLSH2_k127_5463370_10 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000001068 112.0
WLSH2_k127_5463370_11 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000001419 102.0
WLSH2_k127_5463370_12 OstA-like protein K09774 - - 0.000000000000000000002222 102.0
WLSH2_k127_5463370_13 - - - - 0.0006611 48.0
WLSH2_k127_5463370_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 498.0
WLSH2_k127_5463370_3 abc transporter atp-binding protein K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 350.0
WLSH2_k127_5463370_4 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 327.0
WLSH2_k127_5463370_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 308.0
WLSH2_k127_5463370_6 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000002708 227.0
WLSH2_k127_5463370_7 seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing K05808 - - 0.00000000000000000000000000002954 119.0
WLSH2_k127_5463370_8 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000002388 112.0
WLSH2_k127_5463370_9 phosphocarrier protein HPR K11189 - - 0.000000000000000000000000295 111.0
WLSH2_k127_5507962_0 TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type K00123 - 1.17.1.9 0.0 1096.0
WLSH2_k127_5507962_1 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 2.063e-253 806.0
WLSH2_k127_5507962_10 - - - - 0.00000000000000000000001484 110.0
WLSH2_k127_5507962_11 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000006406 99.0
WLSH2_k127_5507962_12 - - - - 0.000000000001344 69.0
WLSH2_k127_5507962_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 478.0
WLSH2_k127_5507962_3 Transcriptional regulatory protein ompR K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 315.0
WLSH2_k127_5507962_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 303.0
WLSH2_k127_5507962_5 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 284.0
WLSH2_k127_5507962_6 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000001616 234.0
WLSH2_k127_5507962_7 - - - - 0.000000000000000000000000000000000000000000000000000000002068 202.0
WLSH2_k127_5507962_8 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000005152 158.0
WLSH2_k127_5507962_9 - - - - 0.00000000000000000000000000000000000005181 154.0
WLSH2_k127_5524523_0 PFAM regulatory protein, MerR K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 362.0
WLSH2_k127_5524523_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 351.0
WLSH2_k127_5524523_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000009212 202.0
WLSH2_k127_5524523_3 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000001107 130.0
WLSH2_k127_5723714_0 - - - - 5.705e-300 921.0
WLSH2_k127_5723714_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 587.0
WLSH2_k127_5723714_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 435.0
WLSH2_k127_5723714_3 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 398.0
WLSH2_k127_5723714_4 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 347.0
WLSH2_k127_5723714_5 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002394 260.0
WLSH2_k127_5723714_6 organic phosphonate transport K02044 - - 0.0000000000000000000000000000000000000004133 161.0
WLSH2_k127_5723714_7 organic phosphonate transport K02044 - - 0.0000000000000000000000000000000000002837 153.0
WLSH2_k127_5723714_8 organic phosphonate transport K02044 - - 0.0000000000000000000000000000000001792 145.0
WLSH2_k127_5731323_0 Abc transporter K15738 - - 1.318e-229 728.0
WLSH2_k127_5731323_1 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 492.0
WLSH2_k127_5731323_2 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 377.0
WLSH2_k127_5731323_3 Pfam:TPM K08988 - - 0.00000000000000000000000000000000018 137.0
WLSH2_k127_5847935_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1146.0
WLSH2_k127_5847935_1 transmembrane transport K02035,K13893 - - 3.117e-223 707.0
WLSH2_k127_5847935_10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 332.0
WLSH2_k127_5847935_11 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 293.0
WLSH2_k127_5847935_12 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000124 119.0
WLSH2_k127_5847935_13 Methyltransferase domain - - - 0.00000000000000000009155 94.0
WLSH2_k127_5847935_14 - - - - 0.000000000007307 74.0
WLSH2_k127_5847935_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 4.983e-213 669.0
WLSH2_k127_5847935_3 Belongs to the ABC transporter superfamily K02031,K02032 - - 9.032e-213 673.0
WLSH2_k127_5847935_4 ABC transporter permease protein K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 514.0
WLSH2_k127_5847935_5 binding-protein-dependent transport systems inner membrane component K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 517.0
WLSH2_k127_5847935_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 400.0
WLSH2_k127_5847935_7 PFAM Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 393.0
WLSH2_k127_5847935_8 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 371.0
WLSH2_k127_5847935_9 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 383.0
WLSH2_k127_5867121_0 Ammonium Transporter Family K03320 - - 1.87e-223 698.0
WLSH2_k127_5867121_1 Bacterial protein of unknown function (DUF945) - - - 0.00000000000000000000000000000000000000246 164.0
WLSH2_k127_5867121_2 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000003967 129.0
WLSH2_k127_5867121_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0003438 43.0
WLSH2_k127_5911624_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 519.0
WLSH2_k127_5911624_1 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 318.0
WLSH2_k127_5911624_2 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000002193 221.0
WLSH2_k127_5911624_3 - - - - 0.000000000000000000000000000000000000000000000000000000000007126 210.0
WLSH2_k127_5911624_4 Zinc transporter zupT K07238 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874 - 0.00000000000000000000000000000000000000000000000000000005092 200.0
WLSH2_k127_5911624_5 THUMP - - - 0.0000000000000000000000000000000000000000001606 166.0
WLSH2_k127_5911624_6 GYD domain - - - 0.00000000000000000000000000000000009752 137.0
WLSH2_k127_5911624_7 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000007761 123.0
WLSH2_k127_5968737_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 537.0
WLSH2_k127_5968737_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 303.0
WLSH2_k127_5968737_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000001223 70.0
WLSH2_k127_5968737_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001168 282.0
WLSH2_k127_5968737_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008801 257.0
WLSH2_k127_5968737_4 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000006178 207.0
WLSH2_k127_5968737_5 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000001293 185.0
WLSH2_k127_5968737_6 MarC family integral membrane protein - - - 0.00000000000000000000000000000000000000000000726 170.0
WLSH2_k127_5968737_7 PFAM Ion transport 2 domain protein - - - 0.000000000000000000000000000000000000000003948 166.0
WLSH2_k127_5968737_8 - - - - 0.0000000000000000000000000001463 129.0
WLSH2_k127_5968737_9 - - - - 0.000000000000000000000000009334 120.0
WLSH2_k127_5997776_0 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 471.0
WLSH2_k127_5997776_1 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009289 260.0
WLSH2_k127_5997776_2 PFAM NnrS family protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000182 257.0
WLSH2_k127_5997776_3 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000003198 180.0
WLSH2_k127_5997776_4 - - - - 0.00000000000000000000000000000000000000006027 158.0
WLSH2_k127_5997776_5 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000008768 142.0
WLSH2_k127_6054070_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.189e-265 823.0
WLSH2_k127_6054070_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.039e-258 798.0
WLSH2_k127_6054070_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000001218 175.0
WLSH2_k127_6054070_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000003307 145.0
WLSH2_k127_6054070_12 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000006837 143.0
WLSH2_k127_6054070_13 Thioredoxin K05838 - - 0.000000000000000000000000000000001532 134.0
WLSH2_k127_6054070_14 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000000000000000000000000005019 126.0
WLSH2_k127_6054070_15 Protein of unknown function (DUF2914) - - - 0.000000000000000000000000002423 118.0
WLSH2_k127_6054070_16 PFAM ATP synthase I chain K02116 GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000004863 74.0
WLSH2_k127_6054070_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000007676 70.0
WLSH2_k127_6054070_18 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0002138 50.0
WLSH2_k127_6054070_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 403.0
WLSH2_k127_6054070_3 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 347.0
WLSH2_k127_6054070_4 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 347.0
WLSH2_k127_6054070_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 336.0
WLSH2_k127_6054070_6 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000569 259.0
WLSH2_k127_6054070_7 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000009573 237.0
WLSH2_k127_6054070_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000001788 184.0
WLSH2_k127_6054070_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000000000000000000001531 180.0
WLSH2_k127_6124600_0 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 2.327e-203 639.0
WLSH2_k127_6124600_1 Chromate transporter K07240 - - 2.787e-201 635.0
WLSH2_k127_6124600_10 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 286.0
WLSH2_k127_6124600_11 PFAM HhH-GPD K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001997 273.0
WLSH2_k127_6124600_12 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003451 254.0
WLSH2_k127_6124600_13 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000015 231.0
WLSH2_k127_6124600_14 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000004998 231.0
WLSH2_k127_6124600_15 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000622 198.0
WLSH2_k127_6124600_16 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000009306 199.0
WLSH2_k127_6124600_17 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000005187 175.0
WLSH2_k127_6124600_18 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000206 153.0
WLSH2_k127_6124600_19 - - - - 0.0000000000000000000000000000000000002702 144.0
WLSH2_k127_6124600_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 522.0
WLSH2_k127_6124600_20 Rhodanese domain protein - - - 0.000000000000000000000000000000006647 131.0
WLSH2_k127_6124600_21 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001825 107.0
WLSH2_k127_6124600_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 502.0
WLSH2_k127_6124600_4 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 355.0
WLSH2_k127_6124600_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 338.0
WLSH2_k127_6124600_6 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 338.0
WLSH2_k127_6124600_7 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 336.0
WLSH2_k127_6124600_8 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 322.0
WLSH2_k127_6124600_9 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 291.0
WLSH2_k127_6196725_0 Domain of unknown function (DUF3400) - - - 0.0 1019.0
WLSH2_k127_6196725_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 435.0
WLSH2_k127_6196725_2 PFAM extracellular solute-binding protein, family 3 K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 366.0
WLSH2_k127_6196725_3 ybak prolyl-trna synthetase associated region K19055 - - 0.0000000000000000000000000000000000000000000574 165.0
WLSH2_k127_6196725_4 Part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000006895 147.0
WLSH2_k127_6196725_5 PFAM Type IV pilus assembly PilZ - - - 0.0000000000000000000000000000000000193 139.0
WLSH2_k127_6196725_6 - - - - 0.00000000000000000001154 97.0
WLSH2_k127_6196725_7 cell redox homeostasis K03671 - - 0.00000000000000000141 93.0
WLSH2_k127_6308999_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.103e-232 734.0
WLSH2_k127_6308999_1 Catalyzes cross-linking of the peptidoglycan cell wall K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 606.0
WLSH2_k127_6308999_10 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 410.0
WLSH2_k127_6308999_11 Amino Acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 377.0
WLSH2_k127_6308999_12 PFAM AMP-dependent synthetase and ligase K01897,K18661 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 357.0
WLSH2_k127_6308999_13 3' exoribonuclease, RNase T-like K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 354.0
WLSH2_k127_6308999_14 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 359.0
WLSH2_k127_6308999_15 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 346.0
WLSH2_k127_6308999_16 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 343.0
WLSH2_k127_6308999_17 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 339.0
WLSH2_k127_6308999_18 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 329.0
WLSH2_k127_6308999_19 PFAM Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 324.0
WLSH2_k127_6308999_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009933 583.0
WLSH2_k127_6308999_20 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 317.0
WLSH2_k127_6308999_21 COG2951 Membrane-bound lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000014 289.0
WLSH2_k127_6308999_22 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000375 250.0
WLSH2_k127_6308999_23 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002006 247.0
WLSH2_k127_6308999_24 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000008578 239.0
WLSH2_k127_6308999_25 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000001441 232.0
WLSH2_k127_6308999_26 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000002264 216.0
WLSH2_k127_6308999_27 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000006436 192.0
WLSH2_k127_6308999_28 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000001389 175.0
WLSH2_k127_6308999_29 Rod shape-determining protein K03569 - - 0.00000000000000000000000000000000000000000000002846 172.0
WLSH2_k127_6308999_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 531.0
WLSH2_k127_6308999_30 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.00000000000000000000000000000000000000000000004253 177.0
WLSH2_k127_6308999_31 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000001204 164.0
WLSH2_k127_6308999_32 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000001453 162.0
WLSH2_k127_6308999_33 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000002578 162.0
WLSH2_k127_6308999_34 DUF218 domain - - - 0.00000000000000000000000000000000000000001925 164.0
WLSH2_k127_6308999_35 - - - - 0.0000000000000000000000000000000000002034 147.0
WLSH2_k127_6308999_36 PFAM Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.00000000000000000000000000000001656 132.0
WLSH2_k127_6308999_37 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000008736 104.0
WLSH2_k127_6308999_38 PFAM RNA recognition motif - - - 0.000000000101 65.0
WLSH2_k127_6308999_39 - - - - 0.00000098 53.0
WLSH2_k127_6308999_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 503.0
WLSH2_k127_6308999_5 COG1012 NAD-dependent aldehyde dehydrogenases K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 484.0
WLSH2_k127_6308999_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 473.0
WLSH2_k127_6308999_7 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 448.0
WLSH2_k127_6308999_8 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 419.0
WLSH2_k127_6308999_9 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 413.0
WLSH2_k127_6324533_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.849e-213 667.0
WLSH2_k127_6324533_1 pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 461.0
WLSH2_k127_6324533_2 Kef-type K transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 423.0
WLSH2_k127_6324533_3 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 310.0
WLSH2_k127_6324533_4 Sulfatase K01002 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006490,GO:0006629,GO:0008150,GO:0008152,GO:0008960,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0042597,GO:0044237,GO:0044238,GO:0044255,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576 2.7.8.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 317.0
WLSH2_k127_6324533_5 - - - - 0.000000000000000000000000000000000000000000000001487 184.0
WLSH2_k127_6382046_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1267.0
WLSH2_k127_6382046_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 566.0
WLSH2_k127_6382046_2 CBS domain containing protein K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 321.0
WLSH2_k127_6382046_3 phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001145 277.0
WLSH2_k127_6382046_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000347 248.0
WLSH2_k127_6382046_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000009654 163.0
WLSH2_k127_6382046_6 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000003343 102.0
WLSH2_k127_6382046_7 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000005855 86.0
WLSH2_k127_6478197_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1718.0
WLSH2_k127_6478197_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 423.0
WLSH2_k127_6478197_2 Rhodanese Homology Domain - - - 0.000000000000000001547 87.0
WLSH2_k127_6572473_0 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000001051 232.0
WLSH2_k127_6572473_1 Esterase-like activity of phytase - - - 0.00000000000000000000000000000000000000000000000000000000009884 216.0
WLSH2_k127_6572473_2 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000001094 177.0
WLSH2_k127_6572473_3 PFAM YCII-related K09780 - - 0.00000000000000000000000000000000000000001357 164.0
WLSH2_k127_6572473_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000003096 131.0
WLSH2_k127_6572473_5 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000101 106.0
WLSH2_k127_6572473_6 Protein of unknown function (DUF1375) - - - 0.000000000001725 71.0
WLSH2_k127_6655121_0 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 402.0
WLSH2_k127_6655121_1 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 352.0
WLSH2_k127_6655121_2 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000144 266.0
WLSH2_k127_6655121_3 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000001265 196.0
WLSH2_k127_6655121_4 Putative thioesterase (yiiD_Cterm) - - - 0.000000000000000000000000000000008033 132.0
WLSH2_k127_6655121_5 Domain of unknown function (DUF4198) - - - 0.00000000000000000000000000000234 130.0
WLSH2_k127_6655121_6 PFAM Bacterial bifunctional deaminase-reductase, C-terminal - - - 0.00000000000000000000000001499 111.0
WLSH2_k127_6655121_7 RibD C-terminal domain - - - 0.000000000000000000003068 99.0
WLSH2_k127_6671345_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 1.842e-293 915.0
WLSH2_k127_6671345_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 8.893e-231 727.0
WLSH2_k127_6671345_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 397.0
WLSH2_k127_6671345_3 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 346.0
WLSH2_k127_6671345_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001342 278.0
WLSH2_k127_6671345_5 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003973 273.0
WLSH2_k127_6671345_6 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000000009797 110.0
WLSH2_k127_6671345_7 Succinate dehydrogenase hydrophobic membrane anchor K00242 - - 0.00000000000000008009 87.0
WLSH2_k127_6671345_8 An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH K09159 GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 - 0.00000000000004481 75.0
WLSH2_k127_6671345_9 PFAM Anti sigma-E protein RseA K03597 - - 0.00000000004825 72.0
WLSH2_k127_6835540_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 5.132e-203 640.0
WLSH2_k127_6835540_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 456.0
WLSH2_k127_6835540_2 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 384.0
WLSH2_k127_6835540_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 360.0
WLSH2_k127_6835540_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 353.0
WLSH2_k127_6835540_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009285 261.0
WLSH2_k127_6835540_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000008491 221.0
WLSH2_k127_6835540_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000001863 59.0
WLSH2_k127_6841465_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 7.6e-234 731.0
WLSH2_k127_6841465_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 510.0
WLSH2_k127_6841465_2 negative regulator of sigma E activity K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000004857 239.0
WLSH2_k127_6882969_0 import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 359.0
WLSH2_k127_6882969_1 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001511 256.0
WLSH2_k127_6882969_2 protein conserved in bacteria K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000007069 232.0
WLSH2_k127_6882969_3 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000001396 187.0
WLSH2_k127_6882969_4 Cupin domain - - - 0.000000000000000000000004371 109.0
WLSH2_k127_6882969_6 Protein of unknown function (DUF465) - - - 0.0000000000008761 76.0
WLSH2_k127_691210_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 5.716e-257 808.0
WLSH2_k127_691210_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00651 - 2.3.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 563.0
WLSH2_k127_691210_10 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000003716 151.0
WLSH2_k127_691210_2 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 453.0
WLSH2_k127_691210_3 Metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 417.0
WLSH2_k127_691210_4 PFAM glutaredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 346.0
WLSH2_k127_691210_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000001341 220.0
WLSH2_k127_691210_6 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000000000000000000000002531 212.0
WLSH2_k127_691210_7 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000008687 200.0
WLSH2_k127_691210_8 CDP-archaeol synthase K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000005972 182.0
WLSH2_k127_691210_9 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 0.0000000000000000000000000000000000000000003369 163.0
WLSH2_k127_6950218_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.758e-268 838.0
WLSH2_k127_6950218_1 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 574.0
WLSH2_k127_6950218_2 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008857 295.0
WLSH2_k127_6950218_3 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002492 257.0
WLSH2_k127_6950218_4 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005623 242.0
WLSH2_k127_6950218_5 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000002666 172.0
WLSH2_k127_6950218_6 Alpha/beta hydrolase family - - - 0.00000000000000000000000004587 112.0
WLSH2_k127_6950218_7 Belongs to the bacterial histone-like protein family - - - 0.00000000000000000000000008751 117.0
WLSH2_k127_6950218_8 Regulatory protein, FmdB family - - - 0.00000000000000000000000051 108.0
WLSH2_k127_7188254_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.395e-271 846.0
WLSH2_k127_7188254_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 549.0
WLSH2_k127_7188254_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000383 187.0
WLSH2_k127_7188254_3 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000002086 187.0
WLSH2_k127_7217795_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 459.0
WLSH2_k127_7217795_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 395.0
WLSH2_k127_7217795_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000003511 213.0
WLSH2_k127_7217795_3 EAL domain - - - 0.00000000000000000000000000000000000000000000000000003139 195.0
WLSH2_k127_7239318_0 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 2.653e-291 917.0
WLSH2_k127_7239318_1 Transcriptional regulator K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006899 275.0
WLSH2_k127_7239318_2 Cytochrome oxidase maturation protein - - - 0.000000000001037 70.0
WLSH2_k127_7239318_3 AAA domain K03496 - - 0.0000000003749 65.0
WLSH2_k127_7296974_0 Glutamate-cysteine ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 575.0
WLSH2_k127_7296974_1 PFAM Type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 552.0
WLSH2_k127_7296974_10 TIGRFAM TonB family protein K03832 - - 0.000000000000000000000000000000000000000000000000000000000003003 219.0
WLSH2_k127_7296974_11 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000632 154.0
WLSH2_k127_7296974_12 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000001516 139.0
WLSH2_k127_7296974_13 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000000003697 120.0
WLSH2_k127_7296974_14 Response regulator receiver domain K02657,K03413 - - 0.00000000000000000000007774 99.0
WLSH2_k127_7296974_2 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 560.0
WLSH2_k127_7296974_3 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 558.0
WLSH2_k127_7296974_4 PFAM type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 530.0
WLSH2_k127_7296974_5 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 524.0
WLSH2_k127_7296974_6 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 477.0
WLSH2_k127_7296974_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 301.0
WLSH2_k127_7296974_8 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000009327 237.0
WLSH2_k127_7296974_9 phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000003868 223.0
WLSH2_k127_7324825_0 synthetase K01908 - 6.2.1.17 2.85e-307 952.0
WLSH2_k127_7324825_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 7.441e-220 691.0
WLSH2_k127_7324825_2 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 587.0
WLSH2_k127_7324825_3 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 583.0
WLSH2_k127_7324825_4 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 416.0
WLSH2_k127_7324825_5 beta-lactamase K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 383.0
WLSH2_k127_7324825_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000039 171.0
WLSH2_k127_7324825_7 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000001213 102.0
WLSH2_k127_7324825_8 Heparinase II/III N-terminus - - - 0.0006682 47.0
WLSH2_k127_7501534_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 547.0
WLSH2_k127_7501534_1 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000001063 166.0
WLSH2_k127_7501534_2 diguanylate cyclase - - - 0.00000000000000000000000000000003157 136.0
WLSH2_k127_7501534_3 Sulfurtransferase TusA - - - 0.00000000002486 66.0
WLSH2_k127_7506692_0 PGAP1-like protein - - - 2.194e-212 664.0
WLSH2_k127_7506692_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000002772 220.0
WLSH2_k127_7506692_2 PFAM NADH Ubiquinone plastoquinone K05568 - - 0.0000000000000000000000000002264 117.0
WLSH2_k127_7540216_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 5.536e-196 619.0
WLSH2_k127_7540216_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 596.0
WLSH2_k127_7540216_10 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 292.0
WLSH2_k127_7540216_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000142 273.0
WLSH2_k127_7540216_12 PFAM toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000001396 195.0
WLSH2_k127_7540216_13 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000005587 173.0
WLSH2_k127_7540216_14 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000003646 151.0
WLSH2_k127_7540216_15 Belongs to the BolA IbaG family - - - 0.0000000000000000000008028 96.0
WLSH2_k127_7540216_16 - - - - 0.0000000000000007524 83.0
WLSH2_k127_7540216_17 NTP binding protein (Contains STAS domain) K07122 - - 0.00000000000002281 79.0
WLSH2_k127_7540216_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 438.0
WLSH2_k127_7540216_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 402.0
WLSH2_k127_7540216_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 378.0
WLSH2_k127_7540216_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 368.0
WLSH2_k127_7540216_6 PFAM ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 355.0
WLSH2_k127_7540216_7 ABC transporter permease K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 353.0
WLSH2_k127_7540216_8 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 337.0
WLSH2_k127_7540216_9 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 327.0
WLSH2_k127_7554183_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1051.0
WLSH2_k127_7554183_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 487.0
WLSH2_k127_7554183_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000001065 124.0
WLSH2_k127_7554183_3 - - - - 0.000000000000000000169 91.0
WLSH2_k127_7554183_4 Protein of unknown function DUF72 - - - 0.0000000000002324 78.0
WLSH2_k127_7578742_0 magnesium chelatase K07391 - - 2.083e-200 636.0
WLSH2_k127_7578742_1 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 548.0
WLSH2_k127_7578742_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002028 260.0
WLSH2_k127_7578742_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000006824 257.0
WLSH2_k127_7578742_4 COG0526 Thiol-disulfide isomerase and thioredoxins K03673 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000008504 179.0
WLSH2_k127_7578742_5 cytochrome - - - 0.000000000000000000000000000000005181 133.0
WLSH2_k127_7578742_6 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000001797 126.0
WLSH2_k127_7578742_7 Membrane fusogenic activity K09806 - - 0.000000000000641 69.0
WLSH2_k127_7578742_8 - - - - 0.0000000000007934 72.0
WLSH2_k127_7717696_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 7.788e-230 721.0
WLSH2_k127_7717696_1 Diguanylate cyclase - - - 1.258e-209 681.0
WLSH2_k127_7717696_10 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 291.0
WLSH2_k127_7717696_11 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003372 294.0
WLSH2_k127_7717696_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000001972 229.0
WLSH2_k127_7717696_13 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000002664 218.0
WLSH2_k127_7717696_14 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001696 220.0
WLSH2_k127_7717696_15 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000003534 205.0
WLSH2_k127_7717696_16 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000002144 203.0
WLSH2_k127_7717696_17 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000001952 192.0
WLSH2_k127_7717696_18 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000131 102.0
WLSH2_k127_7717696_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 591.0
WLSH2_k127_7717696_20 ThiS family K03154 - - 0.0000000000000001005 82.0
WLSH2_k127_7717696_21 - - - - 0.00000001245 58.0
WLSH2_k127_7717696_22 rho-dependent transcription termination K19000 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000303 57.0
WLSH2_k127_7717696_3 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 572.0
WLSH2_k127_7717696_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 466.0
WLSH2_k127_7717696_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 451.0
WLSH2_k127_7717696_6 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 419.0
WLSH2_k127_7717696_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 417.0
WLSH2_k127_7717696_8 tRNA 3'-trailer cleavage K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 366.0
WLSH2_k127_7717696_9 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 342.0
WLSH2_k127_7826770_0 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 393.0
WLSH2_k127_7826770_1 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001925 259.0
WLSH2_k127_7826770_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000001632 233.0
WLSH2_k127_7826770_3 - - - - 0.0000000000000000000000000000000000000000000000000006138 191.0
WLSH2_k127_7826770_4 Rhodanese Homology Domain - - - 0.0000000000002875 71.0
WLSH2_k127_8303464_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 472.0
WLSH2_k127_8303464_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 448.0
WLSH2_k127_8303464_2 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006401 261.0
WLSH2_k127_8303464_3 protein conserved in bacteria K09798 - - 0.0000000000000000000000000000000000000000000000000000000008754 211.0
WLSH2_k127_8303464_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000005165 96.0
WLSH2_k127_8313764_0 Carboxysome shell peptide mid-region - - - 1.773e-194 622.0
WLSH2_k127_8313764_1 Carboxysome Shell Carbonic Anhydrase - - - 6.898e-194 616.0
WLSH2_k127_8313764_10 Pterin 4 alpha carbinolamine dehydratase - - - 0.000000000000000015 85.0
WLSH2_k127_8313764_2 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 440.0
WLSH2_k127_8313764_3 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 301.0
WLSH2_k127_8313764_4 BMC - - - 0.000000000000000000000000000000000000000000000000000000001868 201.0
WLSH2_k127_8313764_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04027 - - 0.0000000000000000000000000000000000000000000000005394 176.0
WLSH2_k127_8313764_6 BMC domain - - - 0.000000000000000000000000000000000000000000000001229 175.0
WLSH2_k127_8313764_7 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000006791 169.0
WLSH2_k127_8313764_8 PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml - - - 0.0000000000000000000000000000000000000001266 151.0
WLSH2_k127_8313764_9 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000000000001543 122.0
WLSH2_k127_83144_0 Sulfate transporter antisigma-factor antagonist STAS - - - 1.117e-301 941.0
WLSH2_k127_83144_1 STAS domain - - - 7.985e-208 677.0
WLSH2_k127_83144_10 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000000004253 201.0
WLSH2_k127_83144_11 Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase K07740 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000002563 154.0
WLSH2_k127_83144_12 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.0000000000000109 79.0
WLSH2_k127_83144_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 9.734e-196 619.0
WLSH2_k127_83144_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 471.0
WLSH2_k127_83144_4 transporter antisigma-factor antagonist STAS K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 448.0
WLSH2_k127_83144_5 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 440.0
WLSH2_k127_83144_6 Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 294.0
WLSH2_k127_83144_7 short-chain dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 289.0
WLSH2_k127_83144_8 PFAM Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000001536 219.0
WLSH2_k127_83144_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000007893 207.0
WLSH2_k127_8327664_0 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 479.0
WLSH2_k127_8327664_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 463.0
WLSH2_k127_8327664_10 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000001465 220.0
WLSH2_k127_8327664_11 Belongs to the beta-ketoacyl-ACP synthases family - - - 0.0000000000000000000000000000000000000000000000000000000000004561 226.0
WLSH2_k127_8327664_12 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000002544 193.0
WLSH2_k127_8327664_13 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000000000007966 130.0
WLSH2_k127_8327664_14 - - - - 0.00000000000000000000000000005617 120.0
WLSH2_k127_8327664_15 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000004478 128.0
WLSH2_k127_8327664_16 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000818 94.0
WLSH2_k127_8327664_17 Phosphopantetheine attachment site K02078 - - 0.000000000000002735 78.0
WLSH2_k127_8327664_18 beta-ketoacyl-acyl-carrier-protein synthase II activity - - - 0.00000000000003636 85.0
WLSH2_k127_8327664_19 membrane - - - 0.000000000002123 77.0
WLSH2_k127_8327664_2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 432.0
WLSH2_k127_8327664_3 Drug resistance transporter Bcr CflA subfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 390.0
WLSH2_k127_8327664_4 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 372.0
WLSH2_k127_8327664_5 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 372.0
WLSH2_k127_8327664_6 Butirosin biosynthesis protein H, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 355.0
WLSH2_k127_8327664_7 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 321.0
WLSH2_k127_8327664_8 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 285.0
WLSH2_k127_8327664_9 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000781 236.0
WLSH2_k127_8349975_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 502.0
WLSH2_k127_8349975_1 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 301.0
WLSH2_k127_8349975_2 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000001072 172.0
WLSH2_k127_8349975_3 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000004599 174.0
WLSH2_k127_8355112_0 Major facilitator superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 569.0
WLSH2_k127_8355112_1 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 282.0
WLSH2_k127_8355112_2 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000009271 196.0
WLSH2_k127_8355112_3 SpoIIAA-like - - - 0.000000000000000000000000000000000000000000000002737 175.0
WLSH2_k127_8355112_4 PFAM RNA-binding S4 domain protein K04762 - - 0.000000000000000000000000001254 129.0
WLSH2_k127_8355112_5 Wd40 repeat-containing protein - - - 0.0000000005318 70.0
WLSH2_k127_8355112_6 - - - - 0.0001577 50.0
WLSH2_k127_8373481_0 Aldehyde K07303 - 1.3.99.16 8.513e-260 816.0
WLSH2_k127_8373481_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000001013 152.0
WLSH2_k127_838288_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 3.616e-237 741.0
WLSH2_k127_838288_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 8.396e-226 710.0
WLSH2_k127_838288_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 298.0
WLSH2_k127_838288_3 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 287.0
WLSH2_k127_8411388_0 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 394.0
WLSH2_k127_8411388_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 291.0
WLSH2_k127_8411388_2 PFAM peptidylprolyl isomerase FKBP-type K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000007227 206.0
WLSH2_k127_8411388_3 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000007509 203.0
WLSH2_k127_8411388_4 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000001181 111.0
WLSH2_k127_8414598_0 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 501.0
WLSH2_k127_8414598_1 PFAM Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 458.0
WLSH2_k127_8414598_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 357.0
WLSH2_k127_8414598_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 313.0
WLSH2_k127_8414598_4 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006915 283.0
WLSH2_k127_8414598_5 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000009144 260.0
WLSH2_k127_8414598_6 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 0.00000002535 55.0
WLSH2_k127_8424677_0 HypF finger - - - 9.537e-283 893.0
WLSH2_k127_8424677_1 Hydrogenase formation hypA family K04654 GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 595.0
WLSH2_k127_8424677_10 PFAM Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002693 258.0
WLSH2_k127_8424677_11 Aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000004122 165.0
WLSH2_k127_8424677_12 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000002332 154.0
WLSH2_k127_8424677_13 HupE / UreJ protein K03192 - - 0.0000000000000000000000000000000000005209 146.0
WLSH2_k127_8424677_14 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000000005132 120.0
WLSH2_k127_8424677_2 AIR synthase related protein, N-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 485.0
WLSH2_k127_8424677_3 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 444.0
WLSH2_k127_8424677_4 ABC-type transport system, involved in lipoprotein release, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 393.0
WLSH2_k127_8424677_5 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 377.0
WLSH2_k127_8424677_6 ABC-type transport system, involved in lipoprotein release, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 372.0
WLSH2_k127_8424677_7 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 303.0
WLSH2_k127_8424677_8 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003231 282.0
WLSH2_k127_8424677_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001207 282.0
WLSH2_k127_8648843_0 Domain of unknown function (DUF4478) K06966 - 3.2.2.10 1.542e-222 697.0
WLSH2_k127_8648843_1 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 338.0
WLSH2_k127_8648843_2 membrane - - - 0.0000000000000000000000000000000000000481 143.0
WLSH2_k127_8698651_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 1.113e-319 983.0
WLSH2_k127_8698651_1 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 610.0
WLSH2_k127_8698651_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004375 277.0
WLSH2_k127_8698651_11 Hydrogenase expression formation protein K03605 - - 0.0000000000000000000000000000000000000000000000003585 186.0
WLSH2_k127_8698651_12 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.000000000000000000000000000003997 127.0
WLSH2_k127_8698651_13 Hydrogenase maturation protease - - - 0.0000000000000000000003171 109.0
WLSH2_k127_8698651_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 603.0
WLSH2_k127_8698651_3 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 539.0
WLSH2_k127_8698651_4 oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 532.0
WLSH2_k127_8698651_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 517.0
WLSH2_k127_8698651_6 formate dehydrogenase, beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 460.0
WLSH2_k127_8698651_7 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 385.0
WLSH2_k127_8698651_8 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 385.0
WLSH2_k127_8698651_9 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 330.0
WLSH2_k127_8714206_0 Bacterial protein of unknown function (DUF839) K07093 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 533.0
WLSH2_k127_8714206_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 483.0
WLSH2_k127_8714206_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 447.0
WLSH2_k127_8714206_3 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 359.0
WLSH2_k127_8714206_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001639 244.0
WLSH2_k127_8714206_5 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000002018 158.0
WLSH2_k127_8714206_6 - - - - 0.0000000000000000000000000000000001281 137.0
WLSH2_k127_8714206_8 - - - - 0.0000000000006173 79.0
WLSH2_k127_8824970_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 3.379e-238 764.0
WLSH2_k127_8824970_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 500.0
WLSH2_k127_8824970_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000989 89.0
WLSH2_k127_8824970_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 422.0
WLSH2_k127_8824970_3 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 430.0
WLSH2_k127_8824970_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 356.0
WLSH2_k127_8824970_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 356.0
WLSH2_k127_8824970_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 314.0
WLSH2_k127_8824970_7 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 309.0
WLSH2_k127_8824970_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000001181 243.0
WLSH2_k127_8824970_9 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000001307 223.0
WLSH2_k127_8867611_0 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 306.0
WLSH2_k127_8867611_1 pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000008848 164.0
WLSH2_k127_8867611_2 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.00000000000000000000000000006526 124.0
WLSH2_k127_8962164_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1344.0
WLSH2_k127_8962164_1 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000001293 191.0
WLSH2_k127_8968697_0 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 346.0
WLSH2_k127_8968697_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 290.0
WLSH2_k127_8968697_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008098 239.0
WLSH2_k127_8968697_3 UPF0056 membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000004334 223.0
WLSH2_k127_9167909_0 Nitronate monooxygenase - - - 6.923e-240 745.0
WLSH2_k127_9167909_1 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 296.0
WLSH2_k127_9167909_2 Peptidoglycan-synthase activator LpoB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004481 258.0
WLSH2_k127_9167909_3 Amidohydrolase K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001371 241.0
WLSH2_k127_9167909_4 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000137 171.0
WLSH2_k127_9167909_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000002418 104.0
WLSH2_k127_9167909_6 Cytochrome b/b6/petB - - - 0.000001232 50.0
WLSH2_k127_9167909_7 cytochrome - - - 0.0007856 46.0
WLSH2_k127_9180144_0 Ecdysteroid kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 601.0
WLSH2_k127_9180144_1 Asparagine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 563.0
WLSH2_k127_9180144_2 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 406.0
WLSH2_k127_9192780_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 313.0
WLSH2_k127_9192780_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 297.0
WLSH2_k127_9192780_2 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000423 289.0
WLSH2_k127_9192780_3 Uncharacterized conserved protein (DUF2183) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003667 285.0
WLSH2_k127_9192780_4 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000008029 224.0
WLSH2_k127_9192780_5 PFAM Amino acid-binding ACT K03567 - - 0.00000000000000000000000000000000000000000000000000000000000001636 231.0
WLSH2_k127_9192780_6 Pfam:DUF479 - - - 0.0000000000000000000000000000000000000000000000000000005089 200.0
WLSH2_k127_9192780_7 PFAM Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000005081 121.0
WLSH2_k127_9192780_8 - - - - 0.000000000000000000000000000006577 123.0
WLSH2_k127_920396_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1268.0
WLSH2_k127_920396_1 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 7.678e-284 882.0
WLSH2_k127_920396_11 6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000002695 228.0
WLSH2_k127_920396_12 - - - - 0.00000000000000000000000000000000000000000000000000000000003437 208.0
WLSH2_k127_920396_13 phosphinothricin N-acetyltransferase activity K03830 - - 0.00000000000000000000000000000000000000000000000004667 183.0
WLSH2_k127_920396_14 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000000008246 156.0
WLSH2_k127_920396_16 lipid catabolic process - - - 0.0000000000000000000000000000000000009385 154.0
WLSH2_k127_920396_17 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000001622 123.0
WLSH2_k127_920396_18 Predicted membrane protein (DUF2061) - - - 0.000000000000000000003953 94.0
WLSH2_k127_920396_19 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000008285 55.0
WLSH2_k127_920396_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 555.0
WLSH2_k127_920396_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 518.0
WLSH2_k127_920396_4 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 503.0
WLSH2_k127_920396_5 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 312.0
WLSH2_k127_920396_6 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004168 285.0
WLSH2_k127_920396_7 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002426 273.0
WLSH2_k127_920396_8 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003217 262.0
WLSH2_k127_920396_9 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001327 263.0
WLSH2_k127_9228470_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 344.0
WLSH2_k127_9228470_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 314.0
WLSH2_k127_9228470_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000191 285.0
WLSH2_k127_9228470_3 PFAM ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000504 228.0
WLSH2_k127_9228470_4 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000397 75.0
WLSH2_k127_9231771_0 AAA domain - - - 1.014e-306 961.0
WLSH2_k127_9231771_1 SMART cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 385.0
WLSH2_k127_9231771_2 COG2829 Outer membrane phospholipase A K01058 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003247 287.0
WLSH2_k127_9231771_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000002839 250.0
WLSH2_k127_9231771_4 cheY-homologous receiver domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000003366 213.0
WLSH2_k127_9231771_5 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000006916 220.0
WLSH2_k127_9231771_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000118 185.0
WLSH2_k127_9231771_7 PFAM UspA - - - 0.00000000000000000000000000000002631 138.0
WLSH2_k127_9231771_9 UPF0391 membrane protein - - - 0.00000002709 57.0
WLSH2_k127_9288667_0 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 509.0
WLSH2_k127_9288667_1 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 309.0
WLSH2_k127_9288667_2 Bacterial lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001666 284.0
WLSH2_k127_9288667_3 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004416 275.0
WLSH2_k127_9288667_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000487 192.0
WLSH2_k127_9288667_5 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000003788 172.0
WLSH2_k127_9288667_6 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.0000000000000002266 81.0
WLSH2_k127_9345932_0 argininosuccinate lyase K01755 - 4.3.2.1 9.515e-224 700.0
WLSH2_k127_9345932_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 404.0
WLSH2_k127_9345932_10 enzyme of heme biosynthesis K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000168 89.0
WLSH2_k127_9345932_11 Protein of unknown function (DUF3106) - - - 0.000000000001004 77.0
WLSH2_k127_9345932_2 Response regulator of the LytR AlgR family K02477,K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001611 259.0
WLSH2_k127_9345932_3 Diguanylate cyclase K13069,K21021 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000002388 248.0
WLSH2_k127_9345932_4 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001231 242.0
WLSH2_k127_9345932_5 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000006038 238.0
WLSH2_k127_9345932_6 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000001259 213.0
WLSH2_k127_9345932_7 Nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000000000000001733 153.0
WLSH2_k127_9345932_8 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000007711 104.0
WLSH2_k127_9345932_9 Thioredoxin-like domain - - - 0.00000000000000000602 90.0
WLSH2_k127_9404756_0 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 325.0
WLSH2_k127_9404756_1 Glycosyl Transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000404 247.0
WLSH2_k127_9404756_2 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000002133 193.0
WLSH2_k127_9404756_3 dehydratase - - - 0.0000000000000000000000000000000001305 138.0
WLSH2_k127_9404756_4 - - - - 0.00000000000001554 79.0
WLSH2_k127_9404756_5 Beta-ketoacyl synthase, N-terminal domain - - - 0.00001355 48.0
WLSH2_k127_9430725_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1063.0
WLSH2_k127_9430725_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 8.538e-250 790.0
WLSH2_k127_9430725_10 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 375.0
WLSH2_k127_9430725_11 Oxygen-insensitive NAD(P)H nitroreductase Dihydropteridine reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002047 278.0
WLSH2_k127_9430725_12 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002631 278.0
WLSH2_k127_9430725_13 PFAM metal-dependent phosphohydrolase, HD sub domain K02103,K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006228 295.0
WLSH2_k127_9430725_14 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001022 268.0
WLSH2_k127_9430725_15 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000002164 261.0
WLSH2_k127_9430725_16 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000148 256.0
WLSH2_k127_9430725_17 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000003315 193.0
WLSH2_k127_9430725_18 - - - - 0.00000000000000000000000000000000000000000000000000479 185.0
WLSH2_k127_9430725_19 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000000000003554 186.0
WLSH2_k127_9430725_2 Periplasmic component of the Tol biopolymer transport system - - - 2.662e-220 716.0
WLSH2_k127_9430725_20 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000001103 160.0
WLSH2_k127_9430725_21 Diguanylate cyclase - - - 0.0000000000000000000000000000000000001441 160.0
WLSH2_k127_9430725_22 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000001641 111.0
WLSH2_k127_9430725_23 RF-1 domain - - - 0.00000000000000000000001185 104.0
WLSH2_k127_9430725_24 integral membrane protein - - - 0.000000000000000000003043 98.0
WLSH2_k127_9430725_25 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000003587 104.0
WLSH2_k127_9430725_26 - - - - 0.00000000000000000001063 93.0
WLSH2_k127_9430725_27 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03789,K03790,K03896 - 2.3.1.102,2.3.1.128 0.000000000000000001933 87.0
WLSH2_k127_9430725_28 - - - - 0.00000000000000002218 85.0
WLSH2_k127_9430725_29 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000003673 57.0
WLSH2_k127_9430725_3 DAHP synthetase I family K03856 - 2.5.1.54 5.134e-198 625.0
WLSH2_k127_9430725_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 569.0
WLSH2_k127_9430725_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 537.0
WLSH2_k127_9430725_6 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 491.0
WLSH2_k127_9430725_7 Belongs to the agmatine deiminase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 482.0
WLSH2_k127_9430725_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 399.0
WLSH2_k127_9430725_9 PFAM Alpha beta hydrolase K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 380.0
WLSH2_k127_947852_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 2279.0
WLSH2_k127_947852_1 crp fnr family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001207 235.0
WLSH2_k127_9501610_0 Aldo keto - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 398.0
WLSH2_k127_9501610_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001908 233.0
WLSH2_k127_9501610_2 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000001669 175.0
WLSH2_k127_9501610_3 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000002505 102.0
WLSH2_k127_9501610_4 Protein of unknown function (DUF504) - - - 0.000000000000000000001333 99.0
WLSH2_k127_9535604_0 Molecular chaperone. Has ATPase activity K04079 - - 6.846e-292 907.0
WLSH2_k127_9535604_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.025e-200 651.0
WLSH2_k127_9535604_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 388.0
WLSH2_k127_9535604_3 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 329.0
WLSH2_k127_9535604_4 UPF0114 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004786 244.0
WLSH2_k127_9535604_5 GtrA-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000007119 228.0
WLSH2_k127_953785_0 FAD linked oxidase K00104 - 1.1.3.15 1.358e-247 777.0
WLSH2_k127_953785_1 4Fe-4S dicluster domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 417.0
WLSH2_k127_953785_2 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 407.0
WLSH2_k127_953785_3 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 299.0
WLSH2_k127_953785_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000001 195.0
WLSH2_k127_953785_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000000000000000003567 155.0
WLSH2_k127_953785_6 - - - - 0.0000000000000000000000001503 112.0
WLSH2_k127_9558479_0 Response regulator receiver K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 567.0
WLSH2_k127_9558479_1 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 302.0
WLSH2_k127_9558479_2 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000002094 170.0
WLSH2_k127_9558479_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000004576 129.0
WLSH2_k127_9602974_0 FMN-binding domain protein K19339 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 559.0
WLSH2_k127_9602974_1 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000004657 196.0
WLSH2_k127_960752_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.4.2.14 6.835e-234 732.0
WLSH2_k127_960752_1 CoA binding domain K09181 - - 1.396e-229 724.0
WLSH2_k127_960752_10 Hydroxypyruvate reductase K11529 - 2.7.1.165 0.000000000000000000000000000000000000000211 156.0
WLSH2_k127_960752_11 Psort location CytoplasmicMembrane, score K03558 - - 0.000000000000000009133 89.0
WLSH2_k127_960752_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.038e-205 648.0
WLSH2_k127_960752_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 611.0
WLSH2_k127_960752_4 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 458.0
WLSH2_k127_960752_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 433.0
WLSH2_k127_960752_6 PFAM Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 419.0
WLSH2_k127_960752_7 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 344.0
WLSH2_k127_960752_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 321.0
WLSH2_k127_960752_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000362 269.0
WLSH2_k127_9607951_0 Fatty acid cis/trans isomerase (CTI) - - - 3.509e-225 723.0
WLSH2_k127_9607951_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 564.0
WLSH2_k127_9607951_2 HD domain - - - 0.0000000000000000000000000000000000000000000229 164.0
WLSH2_k127_9607951_3 Methylmuconolactone methyl-isomerase - - - 0.00000000009943 68.0
WLSH2_k127_9607951_4 - - - - 0.000004721 57.0
WLSH2_k127_9636132_0 Diguanylate cyclase - - - 1.845e-206 668.0
WLSH2_k127_9636132_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 3.02e-196 621.0
WLSH2_k127_9636132_2 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 586.0
WLSH2_k127_9636132_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 522.0
WLSH2_k127_9636132_4 - - - - 0.0000000000000000000001737 100.0
WLSH2_k127_9671913_0 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 401.0
WLSH2_k127_9671913_1 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000006959 183.0
WLSH2_k127_9671913_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000004512 167.0
WLSH2_k127_9681003_0 ABC transporter transmembrane region K06147 - - 3.39e-284 884.0
WLSH2_k127_9681003_1 response regulator K07183 - - 0.00000000000000000000000000000000000000000000000000000351 200.0
WLSH2_k127_9681003_2 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000006427 98.0
WLSH2_k127_9795937_0 daunorubicin resistance ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 450.0
WLSH2_k127_9795937_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 408.0
WLSH2_k127_9795937_10 Fibronectin type 3 domain - - - 0.00000000000000000000002687 114.0
WLSH2_k127_9795937_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K15942 - 2.1.1.288 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 381.0
WLSH2_k127_9795937_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 347.0
WLSH2_k127_9795937_4 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 321.0
WLSH2_k127_9795937_5 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001398 261.0
WLSH2_k127_9795937_6 Protein of unknown function (DUF2938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003278 232.0
WLSH2_k127_9795937_7 PFAM MerR family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000001735 200.0
WLSH2_k127_9795937_8 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000002824 140.0
WLSH2_k127_9795937_9 Protein of unknown function (DUF2798) - - - 0.0000000000000000000000000007243 113.0
WLSH2_k127_982102_0 Diguanylate cyclase - - - 3.105e-246 774.0
WLSH2_k127_982102_1 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 532.0
WLSH2_k127_982102_10 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000002459 217.0
WLSH2_k127_982102_11 von Willebrand factor, type A - - - 0.0000000000000000000000000000000005819 133.0
WLSH2_k127_982102_2 ABC transporter substrate-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 471.0
WLSH2_k127_982102_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 409.0
WLSH2_k127_982102_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 380.0
WLSH2_k127_982102_5 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 367.0
WLSH2_k127_982102_6 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 333.0
WLSH2_k127_982102_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 352.0
WLSH2_k127_982102_8 SMART Signal transduction response regulator, receiver region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001071 258.0
WLSH2_k127_982102_9 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000002443 242.0
WLSH2_k127_9845987_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 3.283e-200 637.0
WLSH2_k127_9845987_1 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 557.0
WLSH2_k127_9845987_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000006019 220.0
WLSH2_k127_9845987_11 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000001098 207.0
WLSH2_k127_9845987_12 - - - - 0.0000000000000000000001296 98.0
WLSH2_k127_9845987_13 - - - - 0.000000000000000000004961 98.0
WLSH2_k127_9845987_2 AMP-dependent synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 309.0
WLSH2_k127_9845987_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K14159 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 300.0
WLSH2_k127_9845987_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 295.0
WLSH2_k127_9845987_5 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 291.0
WLSH2_k127_9845987_6 Methyltransferase type 11 K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000001346 259.0
WLSH2_k127_9845987_7 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004557 250.0
WLSH2_k127_9845987_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000003669 236.0
WLSH2_k127_9845987_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000226 231.0
WLSH2_k127_9960383_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 4.551e-196 620.0
WLSH2_k127_9960383_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000008819 225.0
WLSH2_k127_9960383_2 Involved in the processing of the 5'end of 16S rRNA K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000001248 222.0
WLSH2_k127_9960383_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.00000000000000000000000000000000000000000000000000000002846 200.0
WLSH2_k127_9960383_4 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000001111 194.0
WLSH2_k127_9960383_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000005713 136.0
WLSH2_k127_9960383_6 Processivity clamp loader gamma complex DNA pol III C-term K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000001288 126.0