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Overview

ID MAG04195
Name WLSH2_bin.15
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order GIF9
Family AB-539-J10
Genus RBG-13-51-36
Species
Assembly information
Completeness (%) 60.67
Contamination (%) 0.99
GC content (%) 51.0
N50 (bp) 5,447
Genome size (bp) 1,173,753

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1160

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10054610_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 368.0
WLSH2_k127_10054610_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 352.0
WLSH2_k127_10054610_2 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 330.0
WLSH2_k127_10054610_3 Protein of unknown function (DUF1385) K09153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 311.0
WLSH2_k127_10054610_4 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009703 302.0
WLSH2_k127_10054610_5 Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 297.0
WLSH2_k127_10054610_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000004076 155.0
WLSH2_k127_10054610_7 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000004154 118.0
WLSH2_k127_10054610_8 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000004126 114.0
WLSH2_k127_10054610_9 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000181 111.0
WLSH2_k127_1006708_0 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009067 260.0
WLSH2_k127_1006708_1 Endonuclease containing a URI domain K07461 - - 0.00000000000000000000000000000000006459 135.0
WLSH2_k127_10073994_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000131 155.0
WLSH2_k127_10073994_1 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.00000000000000000000001081 115.0
WLSH2_k127_10073994_2 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000001776 91.0
WLSH2_k127_10073994_3 Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000001649 86.0
WLSH2_k127_10085057_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 1.374e-217 690.0
WLSH2_k127_10085057_1 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 355.0
WLSH2_k127_10085057_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000001184 95.0
WLSH2_k127_10085057_3 PBP superfamily domain K02040 - - 0.000000000000001312 86.0
WLSH2_k127_10140765_0 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.0 1182.0
WLSH2_k127_10140765_1 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1062.0
WLSH2_k127_10140765_10 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006151 229.0
WLSH2_k127_10140765_11 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000001676 209.0
WLSH2_k127_10140765_12 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000001017 191.0
WLSH2_k127_10140765_13 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000004581 186.0
WLSH2_k127_10140765_14 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000000000000001125 177.0
WLSH2_k127_10140765_15 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000003371 141.0
WLSH2_k127_10140765_16 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000005827 136.0
WLSH2_k127_10140765_17 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000001199 138.0
WLSH2_k127_10140765_18 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000001382 126.0
WLSH2_k127_10140765_19 Methyltransferase type 11 - - - 0.000000000000003438 84.0
WLSH2_k127_10140765_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.515e-304 945.0
WLSH2_k127_10140765_20 AAA domain K07028 - - 0.0000000000001473 78.0
WLSH2_k127_10140765_21 - - - - 0.000000000002844 67.0
WLSH2_k127_10140765_22 Biotin-requiring enzyme - - - 0.00000000003265 66.0
WLSH2_k127_10140765_23 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K00558,K13639,K13640 - 2.1.1.37 0.00000000004698 65.0
WLSH2_k127_10140765_24 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000001942 63.0
WLSH2_k127_10140765_25 transferase activity, transferring glycosyl groups - - - 0.000000000368 69.0
WLSH2_k127_10140765_26 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000002613 56.0
WLSH2_k127_10140765_27 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000003488 55.0
WLSH2_k127_10140765_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 496.0
WLSH2_k127_10140765_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 493.0
WLSH2_k127_10140765_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 474.0
WLSH2_k127_10140765_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 391.0
WLSH2_k127_10140765_7 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 322.0
WLSH2_k127_10140765_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003119 275.0
WLSH2_k127_10140765_9 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000888 270.0
WLSH2_k127_10159454_0 Na H ion antiporter subunit K05569 - - 0.000000000000000000000000000000000000000000000000002018 186.0
WLSH2_k127_10159454_1 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.00000000000000000000000000000000005577 140.0
WLSH2_k127_10159454_2 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000000000003035 134.0
WLSH2_k127_10159454_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000000000005109 117.0
WLSH2_k127_10159454_4 Membrane bound hydrogenase - - - 0.0000000000000000000003442 98.0
WLSH2_k127_10159454_5 PFAM multiple resistance and pH regulation protein F K05570 - - 0.000000000000000002877 88.0
WLSH2_k127_10159454_6 Domain of unknown function (DUF4040) - - - 0.0000000000061 68.0
WLSH2_k127_10179641_0 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.000000000000000000000000000000000007997 139.0
WLSH2_k127_10179641_1 Clostripain family - - - 0.0000000000000000000000000001262 129.0
WLSH2_k127_10179641_2 - - - - 0.000000000000000000000000001378 126.0
WLSH2_k127_10219835_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000006559 244.0
WLSH2_k127_10219835_1 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000005156 252.0
WLSH2_k127_10219835_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00006128 51.0
WLSH2_k127_10265414_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 406.0
WLSH2_k127_10265414_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000001394 241.0
WLSH2_k127_10382316_0 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 530.0
WLSH2_k127_10382316_1 methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000005874 242.0
WLSH2_k127_10382316_2 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000006526 124.0
WLSH2_k127_10382316_3 Domain of unknown function (DUF4445) - - - 0.000000000000000000002076 101.0
WLSH2_k127_10382316_4 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000005198 76.0
WLSH2_k127_10399524_0 Putative modulator of DNA gyrase K03568 - - 6.913e-196 623.0
WLSH2_k127_10399524_1 metallopeptidase activity K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 553.0
WLSH2_k127_10399524_2 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 429.0
WLSH2_k127_10399524_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 422.0
WLSH2_k127_10399524_4 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 403.0
WLSH2_k127_10399524_5 nitrogen compound transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 389.0
WLSH2_k127_10404604_0 Telomere recombination K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 462.0
WLSH2_k127_10404604_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000008746 159.0
WLSH2_k127_10404604_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000000000000000000000573 108.0
WLSH2_k127_10407029_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001264 233.0
WLSH2_k127_10407029_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000000875 207.0
WLSH2_k127_10407029_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000001184 183.0
WLSH2_k127_10460885_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 506.0
WLSH2_k127_10460885_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 317.0
WLSH2_k127_10460885_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002668 263.0
WLSH2_k127_10460885_3 RNA recognition motif - - - 0.0000000000000000000000000002957 117.0
WLSH2_k127_10464226_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.695e-258 806.0
WLSH2_k127_10464226_1 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 2.167e-213 672.0
WLSH2_k127_10464226_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000003603 170.0
WLSH2_k127_10464226_11 isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000005896 170.0
WLSH2_k127_10464226_12 Evidence 4 Homologs of previously reported genes of - - - 0.00000000009948 65.0
WLSH2_k127_10464226_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.769e-195 617.0
WLSH2_k127_10464226_3 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 440.0
WLSH2_k127_10464226_4 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 390.0
WLSH2_k127_10464226_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 374.0
WLSH2_k127_10464226_6 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 338.0
WLSH2_k127_10464226_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001746 271.0
WLSH2_k127_10464226_8 Zn-dependent hydrolase, glyoxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006337 239.0
WLSH2_k127_10464226_9 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000002715 185.0
WLSH2_k127_10507509_0 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 519.0
WLSH2_k127_10507509_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000348 196.0
WLSH2_k127_10507509_2 - - - - 0.00000000000002104 74.0
WLSH2_k127_10509592_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 458.0
WLSH2_k127_10509592_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000001558 200.0
WLSH2_k127_10509592_2 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000007503 191.0
WLSH2_k127_10558603_0 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001748 267.0
WLSH2_k127_10558603_1 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000001446 214.0
WLSH2_k127_10558603_2 Methionine biosynthesis protein MetW K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000001425 149.0
WLSH2_k127_10772151_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003581 287.0
WLSH2_k127_10772151_1 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005463 258.0
WLSH2_k127_10772151_3 amine dehydrogenase activity - - - 0.0000000000000000000000004496 123.0
WLSH2_k127_10772151_4 Metallo-peptidase family M12 - - - 0.00002323 58.0
WLSH2_k127_10873573_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 476.0
WLSH2_k127_10873573_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 306.0
WLSH2_k127_10873573_2 Cys/Met metabolism PLP-dependent enzyme K01758,K01761 - 4.4.1.1,4.4.1.11 0.000000000000000001396 91.0
WLSH2_k127_10873573_3 PFAM Cys Met metabolism, pyridoxal phosphate-dependent enzyme K01760 - 4.4.1.8 0.00000000000000003192 87.0
WLSH2_k127_10873573_4 MacB-like periplasmic core domain K02004 - - 0.000000000003173 72.0
WLSH2_k127_10956849_0 haemagglutination activity domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005307 287.0
WLSH2_k127_10956849_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000001083 239.0
WLSH2_k127_10956849_2 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000001348 190.0
WLSH2_k127_10956849_3 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000004017 169.0
WLSH2_k127_10956849_4 Telomere recombination K04656 - - 0.000000000000000000000000000000000000000000008903 168.0
WLSH2_k127_10956849_5 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000001897 76.0
WLSH2_k127_11189661_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 6.505e-231 734.0
WLSH2_k127_11189661_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 340.0
WLSH2_k127_11189661_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000002087 178.0
WLSH2_k127_11189661_3 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000000000000001343 96.0
WLSH2_k127_11218147_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 491.0
WLSH2_k127_11218147_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 457.0
WLSH2_k127_11218147_2 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 449.0
WLSH2_k127_11218147_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 416.0
WLSH2_k127_11218147_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 413.0
WLSH2_k127_11218147_5 PFAM sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000001411 242.0
WLSH2_k127_11218147_6 HIT domain K01518,K02503,K19710,K21220 - 2.5.1.3,2.7.7.53,3.6.1.17 0.000000000000000000000000000000000000000000000000000000000002383 213.0
WLSH2_k127_11218147_7 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000002313 196.0
WLSH2_k127_11218147_8 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000003495 138.0
WLSH2_k127_11223331_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1017.0
WLSH2_k127_11223331_1 Rhodanese-like domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 610.0
WLSH2_k127_11223331_2 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000004689 179.0
WLSH2_k127_11223331_3 Rubrerythrin - - - 0.00000000000000000000000000000001374 138.0
WLSH2_k127_11223331_4 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.00000000000000000000000000000004621 128.0
WLSH2_k127_11223331_5 Mo-molybdopterin cofactor metabolic process - - - 0.0006811 46.0
WLSH2_k127_11233280_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 610.0
WLSH2_k127_11233280_1 GXWXG protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 300.0
WLSH2_k127_11233280_2 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002151 292.0
WLSH2_k127_11233280_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000002118 139.0
WLSH2_k127_11245639_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 518.0
WLSH2_k127_11245639_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 416.0
WLSH2_k127_11245639_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 312.0
WLSH2_k127_11245639_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000001624 219.0
WLSH2_k127_11245639_4 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000005545 139.0
WLSH2_k127_11245639_5 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000004053 110.0
WLSH2_k127_11245639_6 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000004111 79.0
WLSH2_k127_11259970_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 484.0
WLSH2_k127_11259970_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 462.0
WLSH2_k127_11259970_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 348.0
WLSH2_k127_11259970_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000001026 178.0
WLSH2_k127_11357014_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 478.0
WLSH2_k127_11357014_1 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 386.0
WLSH2_k127_11357014_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 378.0
WLSH2_k127_11357014_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 367.0
WLSH2_k127_11357014_4 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 306.0
WLSH2_k127_11357174_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 407.0
WLSH2_k127_11357174_1 EcsC protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 299.0
WLSH2_k127_11357174_2 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000000000000009574 184.0
WLSH2_k127_11357174_3 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000000000000000003252 154.0
WLSH2_k127_11357174_4 Phage integrase family K04763 - - 0.00000000000000000000007796 98.0
WLSH2_k127_11357174_5 PFAM helix-turn-helix domain protein - - - 0.0000000000000002211 82.0
WLSH2_k127_11357174_7 6-phosphogluconolactonase activity K20952 - - 0.00008696 53.0
WLSH2_k127_11357174_8 SWIM zinc finger domain protein - - - 0.0002207 45.0
WLSH2_k127_11357174_9 Helix-turn-helix - - - 0.0006046 45.0
WLSH2_k127_11390930_0 Bacterial dnaA protein K02315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 474.0
WLSH2_k127_11390930_1 Replication initiation and membrane attachment - - - 0.0000000000000000000000000000000000005904 147.0
WLSH2_k127_11390930_3 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000004673 49.0
WLSH2_k127_11442980_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000001058 243.0
WLSH2_k127_11442980_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000775 138.0
WLSH2_k127_11442980_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000008781 115.0
WLSH2_k127_11491055_0 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 314.0
WLSH2_k127_11491055_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000004871 139.0
WLSH2_k127_11491055_2 4Fe-4S binding domain K00171 - 1.2.7.1 0.000000000000000000000000000001617 122.0
WLSH2_k127_11504249_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.361e-239 750.0
WLSH2_k127_11504249_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 4.87e-201 633.0
WLSH2_k127_11543246_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 493.0
WLSH2_k127_11543246_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 468.0
WLSH2_k127_11543246_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000009367 96.0
WLSH2_k127_1178833_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 8.413e-201 632.0
WLSH2_k127_1178833_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 487.0
WLSH2_k127_1178833_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 306.0
WLSH2_k127_1178833_3 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003039 261.0
WLSH2_k127_1178833_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000002177 232.0
WLSH2_k127_1178833_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000344 213.0
WLSH2_k127_1178833_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K01953,K06927 - 6.3.1.14,6.3.5.4 0.00000000000000000000000000008474 128.0
WLSH2_k127_1178833_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - 0.000001104 50.0
WLSH2_k127_1254315_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.0000000000000000000000000000000000000000000000000000000002171 209.0
WLSH2_k127_1254315_1 PFAM transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000006692 211.0
WLSH2_k127_1259173_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1091.0
WLSH2_k127_1259173_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.523e-276 872.0
WLSH2_k127_1259173_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.74e-247 773.0
WLSH2_k127_1259173_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 607.0
WLSH2_k127_1259173_4 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 439.0
WLSH2_k127_1259173_5 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 432.0
WLSH2_k127_1259173_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007329 280.0
WLSH2_k127_1259173_7 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000001629 269.0
WLSH2_k127_1344093_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
WLSH2_k127_1344093_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000004458 116.0
WLSH2_k127_1344093_2 alginic acid biosynthetic process K20276 - - 0.00000000000006811 85.0
WLSH2_k127_1344093_3 Putative Ig domain - - - 0.0000000000001187 85.0
WLSH2_k127_1344093_4 PFAM blue (type 1) copper domain protein K00728,K01179,K13669 - 2.4.1.109,3.2.1.4 0.00000000001752 78.0
WLSH2_k127_1344093_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K01885,K02341,K02343 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,6.1.1.17 0.00005622 48.0
WLSH2_k127_1352617_0 IMG reference gene - - - 7.958e-219 690.0
WLSH2_k127_1352617_1 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 581.0
WLSH2_k127_1352617_2 PFAM lipopolysaccharide biosynthesis protein K16554 - - 0.0000000003801 73.0
WLSH2_k127_1352617_3 Transposase - - - 0.0000000008037 64.0
WLSH2_k127_1460706_0 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 497.0
WLSH2_k127_1460706_1 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000003555 176.0
WLSH2_k127_1469365_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 316.0
WLSH2_k127_1469365_1 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000331 182.0
WLSH2_k127_1469365_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000006245 168.0
WLSH2_k127_1500821_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 565.0
WLSH2_k127_1500821_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000002771 214.0
WLSH2_k127_1500821_2 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000258 208.0
WLSH2_k127_1500821_3 peptidase U32 - - - 0.000000000000000000000006379 103.0
WLSH2_k127_1500821_4 - - - - 0.000000000000000000001394 96.0
WLSH2_k127_1500821_5 - - - - 0.000000000000000000002853 95.0
WLSH2_k127_1500821_6 - - - - 0.000000000000000000004804 94.0
WLSH2_k127_1500821_7 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000667 66.0
WLSH2_k127_1500821_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000003326 62.0
WLSH2_k127_1500821_9 - - - - 0.00000002463 58.0
WLSH2_k127_1525648_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 599.0
WLSH2_k127_1525648_1 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 317.0
WLSH2_k127_1525648_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000184 283.0
WLSH2_k127_1525648_3 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001777 278.0
WLSH2_k127_1525648_4 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000002506 190.0
WLSH2_k127_1525648_5 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000001615 146.0
WLSH2_k127_1525648_6 - - - - 0.00000000000391 67.0
WLSH2_k127_1525648_7 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0002839 44.0
WLSH2_k127_1688101_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1016.0
WLSH2_k127_1688101_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 432.0
WLSH2_k127_1688101_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 308.0
WLSH2_k127_1688101_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000002257 201.0
WLSH2_k127_1688101_4 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.0000000000000005078 79.0
WLSH2_k127_1688101_5 PFAM Integrase core domain - - - 0.00000004452 56.0
WLSH2_k127_1771236_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 513.0
WLSH2_k127_1771236_1 phosphoribosylanthranilate isomerase activity K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000329 212.0
WLSH2_k127_1771236_2 indole-3-glycerol-phosphate synthase activity K01609 - 4.1.1.48 0.000000000000000000000000000000006323 130.0
WLSH2_k127_1773660_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 495.0
WLSH2_k127_1773660_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 335.0
WLSH2_k127_1773660_2 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 314.0
WLSH2_k127_1773660_3 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003822 264.0
WLSH2_k127_1773660_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000003172 49.0
WLSH2_k127_1869985_0 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 437.0
WLSH2_k127_1869985_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 353.0
WLSH2_k127_1869985_2 nitrogen compound transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 337.0
WLSH2_k127_1869985_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000008053 194.0
WLSH2_k127_1899803_0 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 478.0
WLSH2_k127_1899803_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000007517 181.0
WLSH2_k127_1947284_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 416.0
WLSH2_k127_1947284_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 402.0
WLSH2_k127_1947284_2 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 306.0
WLSH2_k127_1947284_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 284.0
WLSH2_k127_1947284_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000002729 180.0
WLSH2_k127_1947284_5 NUDIX domain K17879 - - 0.000000000000002735 78.0
WLSH2_k127_2080033_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000004285 216.0
WLSH2_k127_2080033_1 TIGRFAM signal peptidase I, bacterial type K03100 - 3.4.21.89 0.0000000000000000000000000000000000000003652 155.0
WLSH2_k127_2080033_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000003358 129.0
WLSH2_k127_2080033_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000003596 124.0
WLSH2_k127_2080033_4 Belongs to the peptidase M50B family - - - 0.00000000003363 68.0
WLSH2_k127_2080033_5 - - - - 0.000009178 50.0
WLSH2_k127_2139758_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 579.0
WLSH2_k127_2139758_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 497.0
WLSH2_k127_2139758_2 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 323.0
WLSH2_k127_2139758_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000004753 215.0
WLSH2_k127_2139758_4 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.000000000000000000000000000000000000000000000000001211 188.0
WLSH2_k127_2139758_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000001091 142.0
WLSH2_k127_2139758_6 Trm112p-like protein - - - 0.00000000000000000004628 90.0
WLSH2_k127_2139758_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000001078 91.0
WLSH2_k127_2162203_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 490.0
WLSH2_k127_2162203_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000001406 218.0
WLSH2_k127_2173722_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 4.354e-263 832.0
WLSH2_k127_2173722_1 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 447.0
WLSH2_k127_2173722_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003595 273.0
WLSH2_k127_2173722_3 Winged helix-turn-helix - - - 0.0000000000000000000000001955 107.0
WLSH2_k127_2193243_0 COG2414 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 512.0
WLSH2_k127_2193243_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 456.0
WLSH2_k127_2193243_10 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000748 74.0
WLSH2_k127_2193243_2 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003096 284.0
WLSH2_k127_2193243_3 ligase activity K01469 - 3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
WLSH2_k127_2193243_4 DNA-binding transcription factor activity K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000848 258.0
WLSH2_k127_2193243_5 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000016 252.0
WLSH2_k127_2193243_6 cobalamin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000001044 239.0
WLSH2_k127_2193243_7 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000001264 216.0
WLSH2_k127_2193243_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000009694 195.0
WLSH2_k127_2193243_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000001186 176.0
WLSH2_k127_2231778_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.305e-269 855.0
WLSH2_k127_2231778_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.085e-218 692.0
WLSH2_k127_2231778_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - 2.807e-214 678.0
WLSH2_k127_2231778_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 531.0
WLSH2_k127_2231778_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 375.0
WLSH2_k127_2231778_5 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004274 269.0
WLSH2_k127_2231778_6 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004067 252.0
WLSH2_k127_223193_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 365.0
WLSH2_k127_223193_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000003389 220.0
WLSH2_k127_2271327_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 445.0
WLSH2_k127_2271327_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006478 277.0
WLSH2_k127_2271327_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000009347 211.0
WLSH2_k127_2271327_3 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.00000000000000000000000000000000000004608 147.0
WLSH2_k127_2271327_4 Zincin-like metallopeptidase - - - 0.0000000000000000000000000009925 116.0
WLSH2_k127_2282484_0 PFAM Glutamine cyclotransferase K00683 - 2.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 305.0
WLSH2_k127_2282484_1 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000001126 233.0
WLSH2_k127_2337705_0 phosphorelay sensor kinase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 445.0
WLSH2_k127_2337705_1 PFAM iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000001274 175.0
WLSH2_k127_238218_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 443.0
WLSH2_k127_238218_1 - - - - 0.000000000000000000000000000000002647 134.0
WLSH2_k127_238218_3 amidohydrolase - - - 0.00008702 45.0
WLSH2_k127_243182_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 363.0
WLSH2_k127_243182_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 345.0
WLSH2_k127_243182_2 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001799 261.0
WLSH2_k127_243182_3 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000921 193.0
WLSH2_k127_243182_4 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000321 188.0
WLSH2_k127_243182_5 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000004913 164.0
WLSH2_k127_243182_6 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000003966 128.0
WLSH2_k127_243182_7 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000002957 118.0
WLSH2_k127_243182_8 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000001937 64.0
WLSH2_k127_2581715_0 aminopeptidase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 419.0
WLSH2_k127_2581715_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 403.0
WLSH2_k127_2581715_2 excinuclease ABC - - - 0.0000000000007889 75.0
WLSH2_k127_2646936_0 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000005624 175.0
WLSH2_k127_2646936_1 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000001019 119.0
WLSH2_k127_2646936_2 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000007145 111.0
WLSH2_k127_2651004_0 Transposase K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 391.0
WLSH2_k127_2651004_1 Domain of unknown function (DUF4258) - - - 0.00000000000000000000000001499 111.0
WLSH2_k127_2651004_2 - - - - 0.0000000000000000000001576 98.0
WLSH2_k127_2709224_0 PFAM ferredoxin-dependent glutamate synthase - - - 1.194e-294 909.0
WLSH2_k127_2709224_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 498.0
WLSH2_k127_2709224_2 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 398.0
WLSH2_k127_2709224_3 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 383.0
WLSH2_k127_2709224_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 296.0
WLSH2_k127_2709224_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000005027 184.0
WLSH2_k127_2709224_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000005432 64.0
WLSH2_k127_2730674_0 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 469.0
WLSH2_k127_2730674_1 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 GO:0003674,GO:0005488,GO:0005515,GO:0042802 6.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 381.0
WLSH2_k127_2730674_10 Domain of unknown function (DUF4342) - - - 0.0000000000000000003199 90.0
WLSH2_k127_2730674_11 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000268 90.0
WLSH2_k127_2730674_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 337.0
WLSH2_k127_2730674_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 305.0
WLSH2_k127_2730674_4 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 302.0
WLSH2_k127_2730674_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000275 245.0
WLSH2_k127_2730674_6 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000000000000000000001093 159.0
WLSH2_k127_2730674_7 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000001332 138.0
WLSH2_k127_2730674_9 PFAM Radical SAM domain protein - - - 0.0000000000000000000005781 108.0
WLSH2_k127_2935188_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 585.0
WLSH2_k127_2935188_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 526.0
WLSH2_k127_2935188_2 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 458.0
WLSH2_k127_2935188_3 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000001444 153.0
WLSH2_k127_2967423_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.35e-235 741.0
WLSH2_k127_2967423_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000007107 224.0
WLSH2_k127_2967423_2 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000006714 99.0
WLSH2_k127_2967423_3 PFAM YcfA-like protein - - - 0.000003068 51.0
WLSH2_k127_3031410_0 PFAM FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 526.0
WLSH2_k127_3031410_1 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 290.0
WLSH2_k127_3031410_2 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000001126 215.0
WLSH2_k127_3031410_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000001193 216.0
WLSH2_k127_3031410_4 Protein of unknown function (DUF429) K09147 - - 0.0000000000007519 73.0
WLSH2_k127_3080599_0 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000001202 262.0
WLSH2_k127_3080599_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000007553 238.0
WLSH2_k127_3080599_2 Pfam SNARE associated Golgi protein - - - 0.00000000000000000002965 100.0
WLSH2_k127_3214693_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 425.0
WLSH2_k127_3214693_1 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 383.0
WLSH2_k127_3214693_2 - - - - 0.0000000000000000000007841 101.0
WLSH2_k127_3214693_3 Dodecin K09165 - - 0.00000000000000000001659 93.0
WLSH2_k127_3214693_4 - - - - 0.0000000000001855 71.0
WLSH2_k127_32222_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.082e-268 841.0
WLSH2_k127_32222_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 343.0
WLSH2_k127_32222_2 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 306.0
WLSH2_k127_32222_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 302.0
WLSH2_k127_32222_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000001536 203.0
WLSH2_k127_3302487_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K18016 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 527.0
WLSH2_k127_3302487_1 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 507.0
WLSH2_k127_3302487_2 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 331.0
WLSH2_k127_3302487_3 Belongs to the complex I 20 kDa subunit family K18023 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000006731 242.0
WLSH2_k127_3302487_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000004203 162.0
WLSH2_k127_3302487_5 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K18017 - 1.12.7.2 0.000000000000000000000000000000000000001044 155.0
WLSH2_k127_3302487_6 - - - - 0.00000000000000000001652 94.0
WLSH2_k127_3302487_7 TIGRFAM hydrogenase maturation protease K08315 - 3.4.23.51 0.0000000000000009243 79.0
WLSH2_k127_3319645_0 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 391.0
WLSH2_k127_3319645_1 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000002129 137.0
WLSH2_k127_3319645_2 PQ loop repeat K15383 - - 0.000000000000000000000000002349 113.0
WLSH2_k127_3319645_3 RNA recognition motif - - - 0.0000000000000000000000004215 110.0
WLSH2_k127_3328753_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 449.0
WLSH2_k127_3328753_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 363.0
WLSH2_k127_3328753_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000006036 130.0
WLSH2_k127_3329480_0 Domain of unknown function (DUF1998) K06877 - - 3.057e-230 733.0
WLSH2_k127_3329480_1 Protein of unknown function (DUF503) K09764 - - 0.00000000000001356 75.0
WLSH2_k127_3371585_0 carbon-monoxide dehydrogenase (ferredoxin) activity K00192,K02572,K02573,K14138 - 1.2.7.4,2.3.1.169 7.087e-314 977.0
WLSH2_k127_3371585_1 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 496.0
WLSH2_k127_3371585_2 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K00193,K14138 - 2.3.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 470.0
WLSH2_k127_3371585_3 PFAM CO dehydrogenase beta subunit acetyl-CoA synthase epsilon subunit K00195,K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000001015 194.0
WLSH2_k127_3429750_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 417.0
WLSH2_k127_3429750_1 Penicillin amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 347.0
WLSH2_k127_3429750_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001057 248.0
WLSH2_k127_3429750_3 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000001172 131.0
WLSH2_k127_3451338_0 Dehydrogenase K00294 GO:0003674,GO:0003824,GO:0003842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006536,GO:0006560,GO:0006562,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009507,GO:0009536,GO:0009628,GO:0009651,GO:0009987,GO:0010133,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019752,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0055114,GO:0071704,GO:0072593,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 570.0
WLSH2_k127_3451338_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 449.0
WLSH2_k127_3451338_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 320.0
WLSH2_k127_3451338_3 Saccharopine dehydrogenase - - - 0.0000000000000000000000000000000000000000004283 173.0
WLSH2_k127_3451338_4 oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000003873 134.0
WLSH2_k127_3463234_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 334.0
WLSH2_k127_3463234_1 PFAM Cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000000000001867 186.0
WLSH2_k127_3463234_2 Cysteine-rich domain - - - 0.0000000000000000000000000000000000001779 149.0
WLSH2_k127_3463234_3 4Fe-4S binding domain - - - 0.00000004277 57.0
WLSH2_k127_3463234_4 Helix-turn-helix domain - - - 0.00001065 52.0
WLSH2_k127_3552845_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 406.0
WLSH2_k127_3552845_1 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648,K22317 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 392.0
WLSH2_k127_3552845_2 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 340.0
WLSH2_k127_3552845_3 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000008971 147.0
WLSH2_k127_3552845_4 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone - - - 0.000000000000000000000000000001024 127.0
WLSH2_k127_3552845_5 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000002122 60.0
WLSH2_k127_3552845_6 3-oxoacyl-[acyl-carrier-protein] synthase activity K00646,K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000004666 56.0
WLSH2_k127_3552845_7 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00001275 47.0
WLSH2_k127_3659372_0 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 378.0
WLSH2_k127_3659372_1 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000001096 280.0
WLSH2_k127_3659372_2 COG1233 Phytoene dehydrogenase and related proteins K09835 - 5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000003931 231.0
WLSH2_k127_3789243_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 2.031e-312 993.0
WLSH2_k127_3790698_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1592.0
WLSH2_k127_3790698_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1339.0
WLSH2_k127_3790698_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 467.0
WLSH2_k127_3790698_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 323.0
WLSH2_k127_3790698_4 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 306.0
WLSH2_k127_3790698_5 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002056 265.0
WLSH2_k127_3790698_6 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000009691 239.0
WLSH2_k127_3790698_7 MaoC like domain - - - 0.0000000000000000000000000000000002847 137.0
WLSH2_k127_3790698_8 transcriptional regulator PadR family K10947 - - 0.0000000000000000001234 91.0
WLSH2_k127_3790698_9 - - - - 0.00004785 55.0
WLSH2_k127_3829898_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 343.0
WLSH2_k127_3829898_1 - - - - 0.000000000000000000000000000000000000000002251 169.0
WLSH2_k127_3829898_2 sequence-specific DNA binding K07726 - - 0.000000000000000000000001608 107.0
WLSH2_k127_3829898_3 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0000000000000000000004906 97.0
WLSH2_k127_3829898_4 Chitinase class I K03791 - - 0.00000000000002433 76.0
WLSH2_k127_3904107_0 - - - - 0.0000000000000000000000000000000000000000000009158 177.0
WLSH2_k127_3904107_1 bacterial-type flagellum-dependent cell motility K13276 - - 0.000000000003744 79.0
WLSH2_k127_3904107_2 - - - - 0.00006543 49.0
WLSH2_k127_3904107_3 pyrroloquinoline quinone binding - - - 0.0002452 53.0
WLSH2_k127_3929154_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 323.0
WLSH2_k127_3929154_1 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 297.0
WLSH2_k127_3929154_2 electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000001827 242.0
WLSH2_k127_3929154_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000324 94.0
WLSH2_k127_3929154_4 Mut7-C RNAse domain K09122 - - 0.00000000000000000009906 93.0
WLSH2_k127_3929154_5 Electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000008982 75.0
WLSH2_k127_3929154_6 Mut7-C RNAse domain K09122 - - 0.000000000007552 68.0
WLSH2_k127_39979_0 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 417.0
WLSH2_k127_39979_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 360.0
WLSH2_k127_39979_2 3-keto-5-aminohexanoate cleavage protein K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 339.0
WLSH2_k127_39979_3 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000016 244.0
WLSH2_k127_39979_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000001149 173.0
WLSH2_k127_39979_5 Allophanate hydrolase subunit 2 K01941 - 6.3.4.6 0.00000000000003479 76.0
WLSH2_k127_4157594_0 Protein of unknown function (DUF1016) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 469.0
WLSH2_k127_4157594_1 HNH endonuclease K07454 - - 0.000000000000000000000000000000000000000000000000000000000000009789 226.0
WLSH2_k127_4157594_2 HIT domain - - - 0.00000000000000000000000000000006453 129.0
WLSH2_k127_4157594_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000005534 121.0
WLSH2_k127_4157594_4 Psort location Cytoplasmic, score - - - 0.00000000002385 64.0
WLSH2_k127_4174843_0 Heat shock 70 kDa protein K04043 - - 4.069e-312 967.0
WLSH2_k127_4174843_1 glycine hydroxymethyltransferase activity K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 528.0
WLSH2_k127_4174843_2 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 334.0
WLSH2_k127_4174843_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009651 274.0
WLSH2_k127_4174843_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000002461 130.0
WLSH2_k127_4174843_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000006163 123.0
WLSH2_k127_4174843_6 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000001593 104.0
WLSH2_k127_4178366_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1021.0
WLSH2_k127_4178366_1 DeoC/LacD family aldolase K01635 - 4.1.2.40 0.000000000000000000000000003104 114.0
WLSH2_k127_4178366_2 DeoC/LacD family aldolase K01635 - 4.1.2.40 0.000000000000002508 77.0
WLSH2_k127_4180947_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.0 1138.0
WLSH2_k127_4180947_1 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 402.0
WLSH2_k127_4180947_2 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002215 270.0
WLSH2_k127_4247732_0 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 334.0
WLSH2_k127_4247732_1 - - - - 0.00005108 51.0
WLSH2_k127_4247732_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00005684 46.0
WLSH2_k127_4276838_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1071.0
WLSH2_k127_4276838_1 DNA polymerase X family K02347 - - 5.286e-250 783.0
WLSH2_k127_4276838_2 IMP dehydrogenase / GMP reductase domain K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 437.0
WLSH2_k127_4276838_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 383.0
WLSH2_k127_4276838_4 - - - - 0.0000000000000000000000000000000000000000000000001561 184.0
WLSH2_k127_4276838_5 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000003425 126.0
WLSH2_k127_4299863_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000002511 162.0
WLSH2_k127_4299863_1 - - - - 0.00000000000000000000000000000000000006976 147.0
WLSH2_k127_4299863_2 - - - - 0.00000000805 65.0
WLSH2_k127_4399108_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 495.0
WLSH2_k127_4399108_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003534 275.0
WLSH2_k127_4399108_2 Preprotein translocase SecG subunit K03075 - - 0.000000000000004068 77.0
WLSH2_k127_4399108_3 chitinase K01183 - 3.2.1.14 0.0004832 49.0
WLSH2_k127_4411989_0 Domain of unknown function (DUF4372) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 520.0
WLSH2_k127_4411989_1 - - - - 0.00000000002151 64.0
WLSH2_k127_4411989_2 transferase activity, transferring glycosyl groups K00754,K19422 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0001621 46.0
WLSH2_k127_4431666_0 nuclease activity K06218 - - 0.000000000000000000000000000006095 120.0
WLSH2_k127_4431666_1 Protein of unknown function (DUF433) - - - 0.00000000000000000000001449 102.0
WLSH2_k127_4431666_2 - - - - 0.0000000000000000007902 87.0
WLSH2_k127_4431666_3 nucleic acid-binding protein contains PIN domain - - - 0.0000000000000004799 85.0
WLSH2_k127_4431666_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000002966 64.0
WLSH2_k127_4431666_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000004052 54.0
WLSH2_k127_4431666_6 Domain of unknown function (DUF1902) - - - 0.00000008619 54.0
WLSH2_k127_4431666_7 - - - - 0.0000002747 55.0
WLSH2_k127_4435571_0 Fibronectin type 3 domain - - - 0.000000000000000001057 101.0
WLSH2_k127_4435571_1 Hep Hag repeat protein K01406 - 3.4.24.40 0.000000002666 70.0
WLSH2_k127_4435571_3 tail collar domain protein - - - 0.0003931 53.0
WLSH2_k127_4435571_4 6-phosphogluconolactonase activity K20952 - - 0.0007594 51.0
WLSH2_k127_4504546_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 407.0
WLSH2_k127_4504546_1 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 311.0
WLSH2_k127_4504546_2 SMART regulatory protein, Crp K07730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008478 248.0
WLSH2_k127_4504546_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000001898 210.0
WLSH2_k127_4504546_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000001836 122.0
WLSH2_k127_4504546_5 KH domain K06960 - - 0.00000000000000000004875 91.0
WLSH2_k127_4504546_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000001117 92.0
WLSH2_k127_4608628_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 391.0
WLSH2_k127_4608628_1 PFAM Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 371.0
WLSH2_k127_4608628_2 Transketolase, central region K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 355.0
WLSH2_k127_4608628_3 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000001206 149.0
WLSH2_k127_4612544_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 2.34e-270 848.0
WLSH2_k127_4612544_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 516.0
WLSH2_k127_4612544_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002009 253.0
WLSH2_k127_4612544_11 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000137 251.0
WLSH2_k127_4612544_12 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000003918 256.0
WLSH2_k127_4612544_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001745 233.0
WLSH2_k127_4612544_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000002137 236.0
WLSH2_k127_4612544_15 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
WLSH2_k127_4612544_16 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000003133 219.0
WLSH2_k127_4612544_17 50S ribosomal protein L4 K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002296 211.0
WLSH2_k127_4612544_18 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000001518 181.0
WLSH2_k127_4612544_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000002908 183.0
WLSH2_k127_4612544_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 386.0
WLSH2_k127_4612544_20 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000001974 175.0
WLSH2_k127_4612544_21 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000009698 171.0
WLSH2_k127_4612544_22 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000002094 170.0
WLSH2_k127_4612544_23 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000006336 171.0
WLSH2_k127_4612544_24 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000001983 159.0
WLSH2_k127_4612544_25 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000003035 148.0
WLSH2_k127_4612544_26 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000005826 148.0
WLSH2_k127_4612544_27 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000005938 144.0
WLSH2_k127_4612544_28 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000007935 146.0
WLSH2_k127_4612544_29 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000002341 143.0
WLSH2_k127_4612544_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 376.0
WLSH2_k127_4612544_30 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000002349 140.0
WLSH2_k127_4612544_31 PFAM MaoC like domain - - - 0.0000000000000000000000000000000002406 136.0
WLSH2_k127_4612544_32 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000001308 121.0
WLSH2_k127_4612544_33 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000004045 114.0
WLSH2_k127_4612544_34 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000006286 102.0
WLSH2_k127_4612544_35 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000005165 98.0
WLSH2_k127_4612544_36 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000001237 77.0
WLSH2_k127_4612544_37 structural constituent of ribosome K02904 - - 0.0000000000001404 72.0
WLSH2_k127_4612544_38 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000004013 72.0
WLSH2_k127_4612544_4 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 315.0
WLSH2_k127_4612544_40 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000005898 53.0
WLSH2_k127_4612544_42 dehydratase - - - 0.0001322 50.0
WLSH2_k127_4612544_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 306.0
WLSH2_k127_4612544_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 304.0
WLSH2_k127_4612544_7 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 293.0
WLSH2_k127_4612544_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001026 260.0
WLSH2_k127_4612544_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007314 252.0
WLSH2_k127_467178_0 Rad52/22 family double-strand break repair protein - - - 0.00000000000000000000000000000000000000000000005596 176.0
WLSH2_k127_467178_1 - - - - 0.00000000000000000001024 94.0
WLSH2_k127_467178_2 NinB protein - - - 0.000000000001727 72.0
WLSH2_k127_467178_3 Psort location Cytoplasmic, score 8.96 - - - 0.0000000007614 65.0
WLSH2_k127_467178_4 - - - - 0.00006046 46.0
WLSH2_k127_4694136_0 competence protein - - - 0.0000000000000000000000000000000000000000000000000000000001032 212.0
WLSH2_k127_4694136_1 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000001997 187.0
WLSH2_k127_4694136_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000002541 164.0
WLSH2_k127_4694136_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000000000007303 158.0
WLSH2_k127_4694136_4 - - - - 0.0000000000000000000000000001485 115.0
WLSH2_k127_4751228_0 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 413.0
WLSH2_k127_4751228_1 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 382.0
WLSH2_k127_4751228_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 317.0
WLSH2_k127_4751228_3 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000001241 214.0
WLSH2_k127_4751228_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0006046 45.0
WLSH2_k127_4773725_0 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 385.0
WLSH2_k127_4773725_1 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000006044 235.0
WLSH2_k127_4773725_2 TFIIE alpha subunit - - - 0.00000000000000000000000009526 110.0
WLSH2_k127_4993277_0 Cytochrome c554 and c-prime - - - 3.006e-216 677.0
WLSH2_k127_4993277_1 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 374.0
WLSH2_k127_4993277_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 313.0
WLSH2_k127_5054298_0 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 417.0
WLSH2_k127_5054298_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 362.0
WLSH2_k127_5054298_2 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 302.0
WLSH2_k127_5054298_3 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009055 274.0
WLSH2_k127_5094816_0 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 358.0
WLSH2_k127_5094816_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000004052 114.0
WLSH2_k127_5094816_2 - - - - 0.0000000000007957 69.0
WLSH2_k127_5094816_3 - - - - 0.000000000008959 68.0
WLSH2_k127_5112875_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 605.0
WLSH2_k127_5112875_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 341.0
WLSH2_k127_5112875_2 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000153 250.0
WLSH2_k127_5112875_3 cysteinyl-tRNA aminoacylation K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000265 203.0
WLSH2_k127_5112875_4 NIL - - - 0.000000000000000000000000000000000000000000000000003186 184.0
WLSH2_k127_5112875_5 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000001467 171.0
WLSH2_k127_5112875_6 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000001707 119.0
WLSH2_k127_529403_0 Flavin containing amine oxidoreductase K09516,K09835 - 1.3.99.23,5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 287.0
WLSH2_k127_529403_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000253 227.0
WLSH2_k127_531664_0 acyl-CoA dehydrogenase - - - 1.783e-216 685.0
WLSH2_k127_531664_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000007693 181.0
WLSH2_k127_531664_2 Belongs to the 'phage' integrase family K04763 - - 0.0001273 45.0
WLSH2_k127_5317268_0 Putative cyclase - - - 2.615e-196 617.0
WLSH2_k127_5317268_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 396.0
WLSH2_k127_5317268_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000004897 132.0
WLSH2_k127_5317268_11 - - - - 0.0000000000000366 77.0
WLSH2_k127_5317268_12 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000001685 61.0
WLSH2_k127_5317268_13 domain, Protein - - - 0.00001013 58.0
WLSH2_k127_5317268_2 mannitol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 381.0
WLSH2_k127_5317268_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 317.0
WLSH2_k127_5317268_4 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 306.0
WLSH2_k127_5317268_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000001521 237.0
WLSH2_k127_5317268_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000004513 204.0
WLSH2_k127_5317268_7 PFAM Extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000007648 194.0
WLSH2_k127_5317268_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000001242 173.0
WLSH2_k127_5317268_9 Cupin domain - - - 0.00000000000000000000000000000000000002465 146.0
WLSH2_k127_5335976_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.122e-222 698.0
WLSH2_k127_5335976_1 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000005507 134.0
WLSH2_k127_5335976_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000362 125.0
WLSH2_k127_5335976_3 Phospholipid methyltransferase - - - 0.0000000000000000000000000009318 119.0
WLSH2_k127_5335976_4 Belongs to the UPF0216 family K09737 - - 0.0000000000000004801 84.0
WLSH2_k127_5335976_5 acetyltransferase - - - 0.0000003333 59.0
WLSH2_k127_5404481_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 592.0
WLSH2_k127_5404481_1 TFIIE alpha subunit - - - 0.00000000000000000000000000004873 119.0
WLSH2_k127_5434466_0 elongation factor G K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 624.0
WLSH2_k127_5434466_1 ATPase associated with various cellular activities, AAA_5 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 396.0
WLSH2_k127_5434466_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001343 284.0
WLSH2_k127_5434466_3 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000002377 255.0
WLSH2_k127_5434466_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000002344 238.0
WLSH2_k127_5434466_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000001561 164.0
WLSH2_k127_5434466_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000001226 97.0
WLSH2_k127_5434466_7 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000003391 70.0
WLSH2_k127_5434466_8 Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase - - - 0.0000002493 54.0
WLSH2_k127_5469261_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 508.0
WLSH2_k127_5469261_1 alcohol dehydrogenase K04072 - 1.1.1.1,1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 332.0
WLSH2_k127_5469261_2 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000248 127.0
WLSH2_k127_5479318_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.729e-207 659.0
WLSH2_k127_5479318_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 450.0
WLSH2_k127_5479318_2 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 391.0
WLSH2_k127_5479318_3 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 360.0
WLSH2_k127_5479318_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002127 257.0
WLSH2_k127_5479318_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000006624 194.0
WLSH2_k127_5479318_6 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000008932 146.0
WLSH2_k127_5479318_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000001226 144.0
WLSH2_k127_5479318_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000004903 109.0
WLSH2_k127_5479318_9 Protein of unknown function (DUF448) K02600,K07742 - - 0.0000000000000003907 81.0
WLSH2_k127_5517012_0 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 590.0
WLSH2_k127_5517012_1 GH3 auxin-responsive promoter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 484.0
WLSH2_k127_5517012_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 496.0
WLSH2_k127_5517012_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000003922 220.0
WLSH2_k127_5517012_4 - - - - 0.000000000000000000000111 100.0
WLSH2_k127_5517012_6 Methyltransferase domain - - - 0.00000000000002869 81.0
WLSH2_k127_5517012_7 Double zinc ribbon - - - 0.0000001681 61.0
WLSH2_k127_5517012_8 Protein of unknown function (DUF498/DUF598) - - - 0.0001912 48.0
WLSH2_k127_5537162_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.0 1222.0
WLSH2_k127_5537162_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 418.0
WLSH2_k127_5537162_10 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000006157 55.0
WLSH2_k127_5537162_2 Pfam:Kce K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 393.0
WLSH2_k127_5537162_3 L-phenylalanine transmembrane transporter activity K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 355.0
WLSH2_k127_5537162_4 leucine import across plasma membrane K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 330.0
WLSH2_k127_5537162_5 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 297.0
WLSH2_k127_5537162_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006757 273.0
WLSH2_k127_5537162_7 Similarity to COG0437 Fe-S-cluster-containing hydrogenase components 1(Evalue - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008312 263.0
WLSH2_k127_5537162_8 - - - - 0.00000000000000000000000000000000000000000004631 169.0
WLSH2_k127_5537162_9 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000001901 81.0
WLSH2_k127_559521_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 452.0
WLSH2_k127_559521_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 384.0
WLSH2_k127_559521_2 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000002112 157.0
WLSH2_k127_5646878_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 419.0
WLSH2_k127_5646878_1 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 GO:0003674,GO:0003824,GO:0004553,GO:0004805,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009628,GO:0009651,GO:0009987,GO:0015927,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0019203,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896 3.1.3.12 0.000000000000000000000000000000000656 138.0
WLSH2_k127_5646878_2 transmembrane transport - - - 0.0000000001073 68.0
WLSH2_k127_5700063_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000001307 238.0
WLSH2_k127_5700063_1 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000009331 214.0
WLSH2_k127_5720395_0 phosphoribosylformylglycinamidine synthase K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0007275,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009555,GO:0009570,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0030554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048229,GO:0048856,GO:0055046,GO:0097159,GO:0097367,GO:1901265,GO:1901363 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 537.0
WLSH2_k127_5720395_1 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 284.0
WLSH2_k127_5720395_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K01905,K11175,K22224 - 2.1.2.2,6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000004135 256.0
WLSH2_k127_5720395_3 4Fe-4S dicluster domain K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000469 236.0
WLSH2_k127_5753975_0 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 524.0
WLSH2_k127_5753975_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 494.0
WLSH2_k127_5753975_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001895 284.0
WLSH2_k127_5753975_3 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000000239 203.0
WLSH2_k127_5753975_4 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000006199 173.0
WLSH2_k127_5753975_5 - - - - 0.0000000000000000000000000002428 121.0
WLSH2_k127_5753975_6 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.000000000000000000002057 97.0
WLSH2_k127_5753975_7 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000006334 76.0
WLSH2_k127_5753975_8 - - - - 0.0000005593 55.0
WLSH2_k127_5778953_0 Glycosyltransferase family 20 K16055 - 2.4.1.15,3.1.3.12 4.996e-196 623.0
WLSH2_k127_5778953_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000002881 259.0
WLSH2_k127_5778953_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose - - - 0.00004682 47.0
WLSH2_k127_5788729_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 355.0
WLSH2_k127_5788729_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 290.0
WLSH2_k127_5788729_2 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002118 284.0
WLSH2_k127_5788729_3 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000000000008403 151.0
WLSH2_k127_5788729_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000002441 101.0
WLSH2_k127_5788729_5 Cupin 2 conserved barrel domain - - - 0.000000000000000001844 89.0
WLSH2_k127_5788729_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000003539 71.0
WLSH2_k127_5799594_0 Lon protease (S16) C-terminal proteolytic domain K07177 - - 0.000000000000000000000000000000000000000000000000000000000000003371 239.0
WLSH2_k127_5799594_1 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000008423 156.0
WLSH2_k127_5799594_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000001737 61.0
WLSH2_k127_5804432_0 Homeodomain-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 570.0
WLSH2_k127_5804432_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000136 59.0
WLSH2_k127_5833158_0 sh3 domain protein - - - 0.0000000000000000000000000000000000000002727 169.0
WLSH2_k127_5833158_1 domain, Protein - - - 0.00000000000000000000000000000003096 132.0
WLSH2_k127_5855209_0 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000028 234.0
WLSH2_k127_5864182_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 525.0
WLSH2_k127_5864182_1 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.000000000000000000000000000000000005388 138.0
WLSH2_k127_5864182_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000001493 54.0
WLSH2_k127_5864793_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.134e-251 792.0
WLSH2_k127_5864793_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.176e-203 644.0
WLSH2_k127_5864793_2 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 449.0
WLSH2_k127_5864793_3 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 385.0
WLSH2_k127_5864793_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 298.0
WLSH2_k127_5864793_5 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000003646 161.0
WLSH2_k127_5893910_0 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 317.0
WLSH2_k127_5893910_1 glucose-1-phosphate adenylyltransferase activity K00975 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 0.000000000000000000000000000000000000000000000000000000002713 204.0
WLSH2_k127_5893910_2 Cytidylate kinase-like family - - - 0.00000000599 60.0
WLSH2_k127_5911322_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000618 280.0
WLSH2_k127_5911322_1 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001925 256.0
WLSH2_k127_5914462_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 502.0
WLSH2_k127_5914462_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 284.0
WLSH2_k127_5914462_2 LysE type translocator - - - 0.00000000000000000000000000000000006443 141.0
WLSH2_k127_5914462_3 - - - - 0.0000000000000000000006809 105.0
WLSH2_k127_5914462_4 ABC-2 family transporter protein - - - 0.00000000000000005085 85.0
WLSH2_k127_5914462_5 - - - - 0.0000000000004346 71.0
WLSH2_k127_5914462_6 4-hydroxybenzoate K03179 - 2.5.1.39 0.0007574 51.0
WLSH2_k127_59207_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009205 277.0
WLSH2_k127_59207_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000004708 69.0
WLSH2_k127_59207_2 - K03546 - - 0.000004681 57.0
WLSH2_k127_5951776_0 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 3.438e-264 859.0
WLSH2_k127_5951776_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00123,K00266 - 1.17.1.9,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 330.0
WLSH2_k127_5951776_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000866 163.0
WLSH2_k127_5960176_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 606.0
WLSH2_k127_5960176_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 394.0
WLSH2_k127_5960176_2 Indole-3-glycerol phosphate synthase K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000003047 193.0
WLSH2_k127_5998362_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 542.0
WLSH2_k127_5998362_1 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 420.0
WLSH2_k127_5998362_2 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 373.0
WLSH2_k127_5998362_3 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 319.0
WLSH2_k127_5998362_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172 284.0
WLSH2_k127_5998362_5 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000007918 230.0
WLSH2_k127_5998362_6 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000004277 128.0
WLSH2_k127_5998362_7 translation release factor activity - - - 0.00000000000000006503 90.0
WLSH2_k127_5998362_8 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000008167 81.0
WLSH2_k127_6023587_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 559.0
WLSH2_k127_6023587_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000005835 142.0
WLSH2_k127_6023587_2 Right handed beta helix region - - - 0.00000000003636 76.0
WLSH2_k127_6023587_3 Domain of unknown function (DUF4091) - - - 0.0000004209 55.0
WLSH2_k127_6027210_0 Formate/nitrite transporter K03459,K06212,K21993 GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015318,GO:0015499,GO:0015711,GO:0015718,GO:0015724,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003755 261.0
WLSH2_k127_6027210_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000001321 235.0
WLSH2_k127_6027210_2 Histidine kinase - - - 0.000000000000000000000007229 113.0
WLSH2_k127_6027210_3 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000005178 67.0
WLSH2_k127_6027210_4 cheY-homologous receiver domain - - - 0.00002691 50.0
WLSH2_k127_6074761_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 575.0
WLSH2_k127_6074761_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000001626 218.0
WLSH2_k127_6074761_2 small multidrug export protein - - - 0.00000000000000000000006372 102.0
WLSH2_k127_6074761_3 - - - - 0.00000000000000004887 81.0
WLSH2_k127_6233787_0 DNA polymerase III beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 505.0
WLSH2_k127_6233787_1 decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 376.0
WLSH2_k127_6233787_3 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000171 154.0
WLSH2_k127_62954_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 572.0
WLSH2_k127_62954_1 - - - - 0.0000000000000000000000000001504 118.0
WLSH2_k127_62954_2 - - - - 0.00000000000000000000007424 100.0
WLSH2_k127_62954_3 - - - - 0.00000000000000004447 82.0
WLSH2_k127_62954_4 regulation of response to stimulus - - - 0.000000000000001544 87.0
WLSH2_k127_62954_5 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000003356 53.0
WLSH2_k127_6322688_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 3.695e-217 715.0
WLSH2_k127_6339504_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 5.63e-209 662.0
WLSH2_k127_6339504_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000007798 195.0
WLSH2_k127_6339504_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000157 161.0
WLSH2_k127_6339504_3 PFAM zinc finger, SWIM domain protein - - - 0.0000000000000000000000000000533 119.0
WLSH2_k127_6402072_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.663e-214 675.0
WLSH2_k127_6402072_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 443.0
WLSH2_k127_6402072_10 Helix-turn-helix - - - 0.00000000000000002355 84.0
WLSH2_k127_6402072_11 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000003885 76.0
WLSH2_k127_6402072_2 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 391.0
WLSH2_k127_6402072_3 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 319.0
WLSH2_k127_6402072_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 311.0
WLSH2_k127_6402072_5 oxidoreductase gamma subunit K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000001033 188.0
WLSH2_k127_6402072_6 Protein of unknown function (DUF2851) - - - 0.00000000000000000000000000000000000000000002893 179.0
WLSH2_k127_6402072_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000002267 150.0
WLSH2_k127_6402072_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000001472 140.0
WLSH2_k127_6402072_9 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000000001181 95.0
WLSH2_k127_6406510_0 PFAM Fic DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 422.0
WLSH2_k127_6406510_1 Peptidase C13 family - - - 0.0000000000000000008934 97.0
WLSH2_k127_6406510_2 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.00000000001445 74.0
WLSH2_k127_6475344_0 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000007049 188.0
WLSH2_k127_6475344_1 Peptidase C13 family - - - 0.00000000000000000000001531 107.0
WLSH2_k127_6475344_2 - - - - 0.00000000000000000000001905 105.0
WLSH2_k127_6475344_3 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0000000000004585 70.0
WLSH2_k127_6475344_4 Belongs to the bacterial histone-like protein family - - - 0.0000007924 55.0
WLSH2_k127_6484213_0 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 437.0
WLSH2_k127_6484213_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 336.0
WLSH2_k127_6484213_2 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000001697 183.0
WLSH2_k127_6521506_0 dihydroxy-acid dehydratase activity K01687 - 4.2.1.9 1.055e-251 786.0
WLSH2_k127_6521506_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.122e-243 764.0
WLSH2_k127_6521506_2 ACT domain K01653 - 2.2.1.6 0.00000000000000000000001842 101.0
WLSH2_k127_6560515_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 441.0
WLSH2_k127_6560515_1 alcohol dehydrogenase K04072 - 1.1.1.1,1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 331.0
WLSH2_k127_6560515_2 PFAM UBA THIF-type NAD FAD binding - - - 0.000000000000000000000000000000000000000000000000000000000000006142 230.0
WLSH2_k127_6560515_3 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000002754 133.0
WLSH2_k127_6560515_4 ThiS family K03636 - - 0.000001446 53.0
WLSH2_k127_6561104_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 606.0
WLSH2_k127_6561104_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 430.0
WLSH2_k127_6561104_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000002378 66.0
WLSH2_k127_6652920_0 response regulator, receiver K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 322.0
WLSH2_k127_6652920_1 SMART ATP-binding region ATPase domain protein, histidine kinase A domain protein, histidine kinase HAMP region domain protein K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 324.0
WLSH2_k127_6652920_2 PDZ domain (Also known as DHR or GLGF) - - - 0.0000000000000000000000000000000000000007428 155.0
WLSH2_k127_6652920_3 PFAM regulatory protein LuxR - - - 0.00000000000002036 74.0
WLSH2_k127_6666088_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 505.0
WLSH2_k127_6666088_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 315.0
WLSH2_k127_6707344_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.231e-211 671.0
WLSH2_k127_6707344_1 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000001939 130.0
WLSH2_k127_6707344_2 FAD dependent oxidoreductase - - - 0.00001242 49.0
WLSH2_k127_6788471_0 BadF BadG BcrA BcrD - - - 1.708e-282 902.0
WLSH2_k127_6788471_1 The GLUG motif - - - 0.00000000000000000000000000000000000000000001941 183.0
WLSH2_k127_6797465_0 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 505.0
WLSH2_k127_6797465_2 transcriptional - - - 0.0000000000000000000001121 102.0
WLSH2_k127_6797465_3 - - - - 0.00000002141 57.0
WLSH2_k127_6800419_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 314.0
WLSH2_k127_6800419_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000006411 196.0
WLSH2_k127_6857862_0 Protein of unknown function (DUF559) - - - 4.742e-319 996.0
WLSH2_k127_6857862_1 - - - - 0.000000000000000000000000000002595 125.0
WLSH2_k127_6857862_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000000000000000000002703 125.0
WLSH2_k127_6857862_3 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.000000000006926 68.0
WLSH2_k127_6857862_4 Helix-turn-helix - - - 0.0000001925 57.0
WLSH2_k127_6857862_5 DNA integration K03733,K14059 - - 0.0000007482 53.0
WLSH2_k127_6857862_6 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.000005802 53.0
WLSH2_k127_6857862_7 - - - - 0.0002377 46.0
WLSH2_k127_6960163_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.238e-247 784.0
WLSH2_k127_6960163_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 437.0
WLSH2_k127_6960163_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 392.0
WLSH2_k127_6960163_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000494 272.0
WLSH2_k127_6960163_4 Ribosomal_S15 K02956 - - 0.000000000000000000004145 95.0
WLSH2_k127_6976780_0 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000002118 93.0
WLSH2_k127_6976780_1 2TM domain - - - 0.000000000000001567 79.0
WLSH2_k127_7049263_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 1.214e-201 639.0
WLSH2_k127_7049263_1 DeoC/LacD family aldolase K01635 - 4.1.2.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 350.0
WLSH2_k127_7049263_2 TIGRFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000228 280.0
WLSH2_k127_7065883_0 Pterin binding enzyme K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 346.0
WLSH2_k127_7065883_1 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 312.0
WLSH2_k127_7065883_2 heat shock protein DnaJ domain protein K03686,K05516 - - 0.0000000000000000000000000008905 121.0
WLSH2_k127_7065883_3 - K07018 - - 0.000000000000000000000000002159 113.0
WLSH2_k127_7085703_0 PFAM amidohydrolase 2 K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 394.0
WLSH2_k127_7085703_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 299.0
WLSH2_k127_7085703_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001055 278.0
WLSH2_k127_7085703_3 - - - - 0.00000000000000000000000000000001672 135.0
WLSH2_k127_7085703_4 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000001443 112.0
WLSH2_k127_7085703_5 Resolvase, N terminal domain - - - 0.0004212 53.0
WLSH2_k127_7104262_0 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 300.0
WLSH2_k127_7104262_1 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000002284 251.0
WLSH2_k127_7104262_2 PFAM Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006175 252.0
WLSH2_k127_7104262_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000001475 131.0
WLSH2_k127_7104262_4 toxin-antitoxin pair type II binding - - - 0.000000003532 62.0
WLSH2_k127_7175147_0 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01847,K01848 - 5.4.99.2 1.761e-250 783.0
WLSH2_k127_7175147_1 SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 309.0
WLSH2_k127_7175147_2 Cobalamin B12-binding K01849 - 5.4.99.2 0.00000000000000000000000000000000000001773 145.0
WLSH2_k127_7175147_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000000008497 134.0
WLSH2_k127_7175147_4 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000003541 84.0
WLSH2_k127_721807_0 Ftsk_gamma K03466 - - 4.205e-205 654.0
WLSH2_k127_721807_1 Subtilase family - - - 0.0000000000001062 83.0
WLSH2_k127_721807_2 Parallel beta-helix repeats - - - 0.000000002747 69.0
WLSH2_k127_7281056_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000009484 182.0
WLSH2_k127_7281056_1 low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000007574 140.0
WLSH2_k127_7281056_2 Putative Fe-S cluster - - - 0.000000000000000000000000000000003442 134.0
WLSH2_k127_7281056_3 Thioredoxin domain - - - 0.0000000000000000000001665 99.0
WLSH2_k127_7281056_4 DGC domain - - - 0.0000000000000001194 86.0
WLSH2_k127_7281056_5 - - - - 0.0000000000005641 72.0
WLSH2_k127_7329245_0 Radical SAM domain protein - - - 1.136e-198 631.0
WLSH2_k127_7329245_1 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 528.0
WLSH2_k127_7329245_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 372.0
WLSH2_k127_7329245_3 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000879 290.0
WLSH2_k127_7329245_4 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000004873 252.0
WLSH2_k127_7329245_5 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000003688 201.0
WLSH2_k127_7329245_6 dUTPase K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000151 181.0
WLSH2_k127_7329245_7 acetyltransferase K18815 - 2.3.1.82 0.000000000000000000000000000000000325 137.0
WLSH2_k127_7402845_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 548.0
WLSH2_k127_7402845_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 478.0
WLSH2_k127_7402845_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000005816 206.0
WLSH2_k127_7402845_3 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000002925 91.0
WLSH2_k127_7459064_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 327.0
WLSH2_k127_7459064_1 - - - - 0.00000000000000000000000000000000000000000000001919 177.0
WLSH2_k127_7459064_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000002249 145.0
WLSH2_k127_7459064_3 Domain of unknown function (DUF1998) K06877 - - 0.00000000000000000000000000000006386 125.0
WLSH2_k127_7459064_4 Belongs to the Fur family K09823 - - 0.00000000000000003243 87.0
WLSH2_k127_7465533_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 8.106e-231 734.0
WLSH2_k127_7465533_1 arginine biosynthetic process via ornithine K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 546.0
WLSH2_k127_7465533_2 Dak1_2 K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 507.0
WLSH2_k127_7465533_3 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 335.0
WLSH2_k127_7465533_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002911 274.0
WLSH2_k127_7465533_5 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001038 264.0
WLSH2_k127_7465533_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000001089 154.0
WLSH2_k127_7465533_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000264 165.0
WLSH2_k127_7465533_8 Ribosomal L28 family K02902 - - 0.000000000000009593 76.0
WLSH2_k127_7465533_9 - - - - 0.00008576 51.0
WLSH2_k127_7529087_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.481e-269 849.0
WLSH2_k127_7529087_1 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 565.0
WLSH2_k127_7529087_2 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 370.0
WLSH2_k127_7529087_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000008107 212.0
WLSH2_k127_7529087_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000002716 181.0
WLSH2_k127_7529087_5 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000007364 80.0
WLSH2_k127_7567724_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K16264 - - 0.000000000000000000000000000000000000000000000000000000294 203.0
WLSH2_k127_7567724_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000005527 190.0
WLSH2_k127_7567724_2 Amidohydrolase family - - - 0.000000000000005314 79.0
WLSH2_k127_7625521_0 PFAM Beta propeller domain K14475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 471.0
WLSH2_k127_7625521_1 Secreted protein with C-terminal beta-propeller domain - - - 0.0000000000000000000000000000000000002726 150.0
WLSH2_k127_7625521_2 DNA-templated transcription, initiation K03088 - - 0.000000000000005511 79.0
WLSH2_k127_7672588_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 341.0
WLSH2_k127_7672588_1 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 289.0
WLSH2_k127_7672588_2 acyl-CoA dehydrogenase - - - 0.000000145 54.0
WLSH2_k127_7870986_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 531.0
WLSH2_k127_7870986_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000002218 269.0
WLSH2_k127_7870986_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008424 228.0
WLSH2_k127_7870986_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000005189 231.0
WLSH2_k127_7870986_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.000000000000000000000000000000001352 134.0
WLSH2_k127_7870986_5 GYD domain - - - 0.00000000000000000000000000000005214 126.0
WLSH2_k127_7870986_6 Domain of unknown function (DUF4347) - - - 0.00000000000000000000000000001069 138.0
WLSH2_k127_7870986_7 C-terminal domain of CHU protein family - - - 0.00000000000000001651 98.0
WLSH2_k127_7870986_8 Leucine-rich repeat (LRR) protein - - - 0.0000000000004642 83.0
WLSH2_k127_7887149_0 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000004889 152.0
WLSH2_k127_7887149_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000487 103.0
WLSH2_k127_7887149_2 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000003736 102.0
WLSH2_k127_7887149_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000008821 96.0
WLSH2_k127_7887149_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000001863 92.0
WLSH2_k127_7887149_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000002274 79.0
WLSH2_k127_7887149_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000005533 69.0
WLSH2_k127_7887149_7 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.0002948 47.0
WLSH2_k127_7902295_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 421.0
WLSH2_k127_7902295_1 SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 316.0
WLSH2_k127_7902295_2 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000004037 145.0
WLSH2_k127_7902295_3 Alcohol dehydrogenase GroES-like domain - - - 0.000000000005866 69.0
WLSH2_k127_7949165_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 486.0
WLSH2_k127_7949165_1 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000001475 185.0
WLSH2_k127_7962725_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 466.0
WLSH2_k127_7962725_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004876 247.0
WLSH2_k127_7962725_2 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000006487 187.0
WLSH2_k127_8067095_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 9.76e-242 751.0
WLSH2_k127_8067095_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 492.0
WLSH2_k127_8067095_2 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 306.0
WLSH2_k127_8067095_3 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 286.0
WLSH2_k127_8073706_0 PFAM glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002188 274.0
WLSH2_k127_8073706_1 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000007755 186.0
WLSH2_k127_8073706_2 Predicted permease K07089 - - 0.00000000000000000000000000000000000000004346 164.0
WLSH2_k127_8073706_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000004215 113.0
WLSH2_k127_8073706_4 Galactose oxidase, central domain - - - 0.00000000000000000003498 102.0
WLSH2_k127_8073706_5 PFAM permease K07089 - - 0.00000000000000005698 85.0
WLSH2_k127_8073706_6 intermembrane phospholipid transfer K07323 - - 0.000000114 62.0
WLSH2_k127_8083843_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 375.0
WLSH2_k127_8083843_1 Methyl-viologen-reducing hydrogenase, delta subunit K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 329.0
WLSH2_k127_8083843_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 311.0
WLSH2_k127_8083843_3 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009217 265.0
WLSH2_k127_8083843_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000003318 151.0
WLSH2_k127_8106485_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 523.0
WLSH2_k127_8106485_1 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000004113 219.0
WLSH2_k127_8106485_2 BadF BadG BcrA BcrD - - - 0.000000000000000000000000000000000000000000308 169.0
WLSH2_k127_8106485_3 Transcriptional regulator PadR-like family K10947 - - 0.0000000000000002072 83.0
WLSH2_k127_8119115_0 enoyl-CoA hydratase K20036 - 4.2.1.155 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003535 284.0
WLSH2_k127_8119115_1 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000003263 155.0
WLSH2_k127_8119115_2 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000005437 95.0
WLSH2_k127_8119115_3 cellulose binding - - - 0.000003755 60.0
WLSH2_k127_81739_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 327.0
WLSH2_k127_81739_1 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 294.0
WLSH2_k127_81739_2 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000003916 168.0
WLSH2_k127_8290404_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000003375 166.0
WLSH2_k127_8290404_1 Histidine kinase - - - 0.0000000003219 67.0
WLSH2_k127_8290404_2 COG2801 Transposase and inactivated derivatives K07497 - - 0.00005441 46.0
WLSH2_k127_8290404_3 transposase activity K07483,K07497 - - 0.0003912 43.0
WLSH2_k127_8321966_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001225 239.0
WLSH2_k127_8321966_1 PFAM NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000137 225.0
WLSH2_k127_8321966_2 2Fe-2S iron-sulfur cluster binding domain K00123 - 1.17.1.9 0.0000000000000000000000000000003976 137.0
WLSH2_k127_8347797_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.184e-232 745.0
WLSH2_k127_8347797_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 434.0
WLSH2_k127_8347797_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 407.0
WLSH2_k127_8347797_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00002856 46.0
WLSH2_k127_8372755_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001057 262.0
WLSH2_k127_8372755_1 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009499 251.0
WLSH2_k127_8372755_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000007907 199.0
WLSH2_k127_8372755_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000009215 165.0
WLSH2_k127_8372755_4 Flavodoxin domain - - - 0.000000000000000000000000000000000000000001658 158.0
WLSH2_k127_8372755_5 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000002012 139.0
WLSH2_k127_8372755_6 Flavodoxin - GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000392 44.0
WLSH2_k127_8376202_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 425.0
WLSH2_k127_8376202_1 Sugar (pentulose and hexulose) kinases K00854 - 2.7.1.17 0.00000000000000000000000004253 109.0
WLSH2_k127_8376202_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000808 63.0
WLSH2_k127_8426204_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.072e-199 643.0
WLSH2_k127_8426204_1 Phospholipid methyltransferase - - - 0.000000000000000000000000001551 119.0
WLSH2_k127_843569_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004051 278.0
WLSH2_k127_843569_1 Protein of unknown function (DUF401) K09133 - - 0.0000000000000000000000000000000000000000000000000000000001918 218.0
WLSH2_k127_8518518_0 PFAM WD-40 repeat - - - 0.000000000000000000000000000000000000000000000000000001811 216.0
WLSH2_k127_8518518_1 - - - - 0.000000000000000000000000000000002542 149.0
WLSH2_k127_8518518_2 PEP-CTERM motif - - - 0.0000000000000000000002111 105.0
WLSH2_k127_8518518_3 - - - - 0.000000000000001231 91.0
WLSH2_k127_8518518_4 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.00000000000001149 73.0
WLSH2_k127_8518518_5 Conserved repeat domain - - - 0.00000001537 68.0
WLSH2_k127_8530885_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 6.8e-308 958.0
WLSH2_k127_858713_0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) K05947 - 2.4.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 443.0
WLSH2_k127_858713_1 Protein of unknown function (DUF933) K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001927 251.0
WLSH2_k127_858713_2 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.0000000000000000000000000000000000000000000000000000000000000000000000074 251.0
WLSH2_k127_858713_3 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000002152 228.0
WLSH2_k127_8620267_0 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000004623 271.0
WLSH2_k127_8620267_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14387 - - 0.000000000000000000000000000000000000000000000000000000000000242 229.0
WLSH2_k127_8620267_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000001911 165.0
WLSH2_k127_8620267_3 domain protein - - - 0.0000000000000000004311 97.0
WLSH2_k127_8667695_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 1.404e-312 968.0
WLSH2_k127_8667695_1 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 557.0
WLSH2_k127_8667695_2 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 466.0
WLSH2_k127_8667695_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 467.0
WLSH2_k127_8667695_4 Helix-turn-helix XRE-family like proteins - - - 0.0000004094 57.0
WLSH2_k127_8667695_5 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000001909 56.0
WLSH2_k127_866795_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000004375 238.0
WLSH2_k127_866795_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000001716 192.0
WLSH2_k127_866795_2 Glycoprotease family - - - 0.000000000000000000000000000000000000000000000000009816 194.0
WLSH2_k127_866795_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000095 168.0
WLSH2_k127_866795_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000005452 153.0
WLSH2_k127_866795_5 PFAM peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000002222 150.0
WLSH2_k127_866795_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000001799 121.0
WLSH2_k127_866795_7 Thioesterase superfamily protein - - - 0.00000000000000000000008506 111.0
WLSH2_k127_8687813_0 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 436.0
WLSH2_k127_8687813_1 Transposase - - - 0.00000000000000000000000000000000001818 140.0
WLSH2_k127_8687813_2 - - - - 0.000000000000000000000000222 107.0
WLSH2_k127_8687813_3 - - - - 0.000003578 49.0
WLSH2_k127_8704747_0 Belongs to the peptidase S8 family K13274,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 336.0
WLSH2_k127_8704747_1 Conserved repeat domain - - - 0.000000000000000000001148 111.0
WLSH2_k127_8704747_2 PFAM DSBA oxidoreductase - - - 0.000000000000000007306 91.0
WLSH2_k127_8704747_3 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000000311 68.0
WLSH2_k127_8704747_4 toxin-antitoxin pair type II binding K19159 - - 0.00002144 51.0
WLSH2_k127_8734798_0 Flavin containing amine oxidoreductase K09516,K09835 - 1.3.99.23,5.2.1.13 0.00000000000000000000000000000000000000000000000005972 182.0
WLSH2_k127_8734798_2 AraC-like ligand binding domain - - - 0.00000000000000000000000000000001402 128.0
WLSH2_k127_8840580_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 308.0
WLSH2_k127_8840580_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000801 266.0
WLSH2_k127_8840580_2 polysaccharide deacetylase - - - 0.0000000642 61.0
WLSH2_k127_8870936_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 458.0
WLSH2_k127_8870936_1 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 296.0
WLSH2_k127_8870936_2 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 302.0
WLSH2_k127_8870936_3 carotenoid biosynthetic process K10212 - - 0.0000000000000000000000000000000000007601 145.0
WLSH2_k127_8870936_4 Belongs to the Fur family K09825 - - 0.00000000000000000000000000000000001027 140.0
WLSH2_k127_8870936_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000007605 113.0
WLSH2_k127_8882060_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 420.0
WLSH2_k127_8882060_1 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 340.0
WLSH2_k127_8882060_2 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000287 268.0
WLSH2_k127_8882060_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000007969 228.0
WLSH2_k127_9142613_0 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007669 275.0
WLSH2_k127_9142613_1 ATP-grasp domain K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000284 246.0
WLSH2_k127_9142613_2 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000001539 151.0
WLSH2_k127_9142613_3 PFAM methyltransferase - - - 0.000000000000443 79.0
WLSH2_k127_9145203_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 347.0
WLSH2_k127_9145203_1 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000003618 264.0
WLSH2_k127_9145203_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000002557 177.0
WLSH2_k127_9145203_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000004474 59.0
WLSH2_k127_9145203_4 acetyltransferase - - - 0.0002154 52.0
WLSH2_k127_9172773_0 Elongation factor G C-terminus K06207 - - 1.035e-253 792.0
WLSH2_k127_9172773_1 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000008603 209.0
WLSH2_k127_9172773_2 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000000000002716 149.0
WLSH2_k127_9201208_0 Belongs to the ClpA ClpB family K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 491.0
WLSH2_k127_9201208_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 316.0
WLSH2_k127_9201208_2 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000001903 107.0
WLSH2_k127_9215031_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 388.0
WLSH2_k127_9215031_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000002789 196.0
WLSH2_k127_9215031_2 Class ii aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000006802 177.0
WLSH2_k127_9233949_0 DNA restriction-modification system - - - 1.12e-199 634.0
WLSH2_k127_9233949_1 XamI restriction endonuclease K01155 - 3.1.21.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 295.0
WLSH2_k127_9233949_2 XamI restriction endonuclease K01155 - 3.1.21.4 0.0000000000000000000000000000000000000000000000000000000003917 205.0
WLSH2_k127_9233949_3 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000005493 141.0
WLSH2_k127_9233949_4 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000003875 109.0
WLSH2_k127_9233949_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000007696 106.0
WLSH2_k127_9235762_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 331.0
WLSH2_k127_9235762_1 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000005408 208.0
WLSH2_k127_9256018_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1264.0
WLSH2_k127_9256018_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000002416 85.0
WLSH2_k127_9291453_0 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000009239 230.0
WLSH2_k127_9291453_1 Na H ion antiporter subunit K05569 - - 0.000000000000000000000000000000000000000000000000001472 187.0
WLSH2_k127_9291453_2 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.000000000000000000000000000000000006184 143.0
WLSH2_k127_9291453_3 Na+/H+ antiporter subunit K05571 - - 0.00000000000000000000000000000125 124.0
WLSH2_k127_9291453_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000001938 123.0
WLSH2_k127_9291453_5 Membrane bound hydrogenase - - - 0.00000000000000000000001056 102.0
WLSH2_k127_9291453_6 PFAM multiple resistance and pH regulation protein F K05570 - - 0.000000000000000009766 86.0
WLSH2_k127_9291453_7 Domain of unknown function (DUF4040) - - - 0.0000000000002243 74.0
WLSH2_k127_9306614_0 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 449.0
WLSH2_k127_9306614_1 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003888 285.0
WLSH2_k127_9306614_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000001099 219.0
WLSH2_k127_9306614_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000002115 136.0
WLSH2_k127_9306614_4 Bacterial regulatory protein, Fis family K07712 - - 0.00000000000000000007426 97.0
WLSH2_k127_9306614_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000001203 65.0
WLSH2_k127_9338701_0 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004041 246.0
WLSH2_k127_9338701_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000009561 165.0
WLSH2_k127_9338701_2 - - - - 0.000000000000000000000000000000000006732 147.0
WLSH2_k127_9338701_3 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000001307 124.0
WLSH2_k127_9338701_4 4Fe-4S dicluster domain - - - 0.000000000000000000000007601 104.0
WLSH2_k127_9373010_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006718 485.0
WLSH2_k127_9373010_1 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000037 267.0
WLSH2_k127_9373010_2 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000007299 121.0
WLSH2_k127_9373010_3 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000004398 111.0
WLSH2_k127_9373010_4 viral genome integration into host DNA K04763 - - 0.0000000000000000000000003277 105.0
WLSH2_k127_9373010_5 - - - - 0.000000000000000000000001047 105.0
WLSH2_k127_9373010_6 mRNA binding K07339 - - 0.00001053 49.0
WLSH2_k127_950963_0 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 304.0
WLSH2_k127_950963_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000005111 145.0
WLSH2_k127_950963_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00006997 49.0
WLSH2_k127_9547016_0 Belongs to the RimK family K05844 - - 0.000000005677 66.0
WLSH2_k127_9547016_1 SIS domain K00820 - 2.6.1.16 0.000005231 59.0
WLSH2_k127_9569297_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.294e-240 761.0
WLSH2_k127_9569297_1 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 407.0
WLSH2_k127_9569297_2 COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001311 302.0
WLSH2_k127_9569297_3 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000002681 221.0
WLSH2_k127_9569297_4 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000005819 215.0
WLSH2_k127_9569297_5 Large-conductance mechanosensitive channel, MscL K03282 - - 0.000000000000000000000000000000000000000000000000000002813 193.0
WLSH2_k127_9569297_6 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000001028 187.0
WLSH2_k127_9569297_7 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000000000000001119 181.0
WLSH2_k127_9589784_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 475.0
WLSH2_k127_9589784_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003388 290.0
WLSH2_k127_9589784_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000009287 251.0
WLSH2_k127_9589784_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000003552 226.0
WLSH2_k127_9622152_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 527.0
WLSH2_k127_9622152_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 399.0
WLSH2_k127_9622152_2 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000000001285 138.0
WLSH2_k127_9637669_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 316.0
WLSH2_k127_9637669_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001392 276.0
WLSH2_k127_9637669_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000002403 178.0
WLSH2_k127_9696992_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 466.0
WLSH2_k127_9696992_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 451.0
WLSH2_k127_9696992_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005449 284.0
WLSH2_k127_9696992_3 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001808 221.0
WLSH2_k127_9696992_4 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000002359 201.0
WLSH2_k127_9696992_5 S-layer homology domain - - - 0.000000000001886 79.0
WLSH2_k127_9697093_0 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 334.0
WLSH2_k127_9697093_1 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 313.0
WLSH2_k127_9697093_2 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001832 267.0
WLSH2_k127_9697093_3 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000006281 219.0
WLSH2_k127_9697093_4 PFAM Integrase, catalytic region - - - 0.0000000000000000000000000000000000000000005135 161.0
WLSH2_k127_9697093_5 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000001017 117.0
WLSH2_k127_9697093_6 PFAM transposase IS116 IS110 IS902 family - - - 0.000000000000000000003441 100.0
WLSH2_k127_9703631_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000009116 227.0
WLSH2_k127_9703631_1 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000002316 172.0
WLSH2_k127_9703631_2 AhpC/TSA family - - - 0.000000000000000197 86.0
WLSH2_k127_9710692_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1564.0
WLSH2_k127_9710692_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000005469 214.0
WLSH2_k127_9710692_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000007637 167.0
WLSH2_k127_9710692_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.00000000000000000000000006265 108.0
WLSH2_k127_9713232_0 Aminotransferase class I and II K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 548.0
WLSH2_k127_9713232_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 416.0
WLSH2_k127_9713232_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 287.0
WLSH2_k127_9713232_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000007241 232.0
WLSH2_k127_9713232_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000003324 72.0
WLSH2_k127_9746390_0 carboxylase, biotin carboxylase K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 457.0
WLSH2_k127_9746390_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 383.0
WLSH2_k127_9746390_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 331.0
WLSH2_k127_9746390_3 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002298 269.0
WLSH2_k127_9746390_4 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002226 250.0
WLSH2_k127_9746390_5 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component K04113 - 1.3.7.8 0.0003874 48.0
WLSH2_k127_9895914_0 Ferrous iron transport protein B K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 349.0
WLSH2_k127_9895914_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 334.0
WLSH2_k127_9895914_2 SMART iron dependent repressor K03709 - - 0.0000000000000000000000000000001377 129.0
WLSH2_k127_9895914_3 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000001741 92.0
WLSH2_k127_9895914_4 FeoA K04758 - - 0.00000000000000006683 83.0
WLSH2_k127_9929306_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 593.0
WLSH2_k127_9929306_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 384.0
WLSH2_k127_9929306_2 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 322.0
WLSH2_k127_9929306_3 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000009791 241.0
WLSH2_k127_9929306_4 RNase_H superfamily K07502 - - 0.000009006 55.0
WLSH2_k127_9945949_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000001499 174.0
WLSH2_k127_9945949_1 - - - - 0.0000000000000000000000000000000005939 135.0
WLSH2_k127_9945949_2 - - - - 0.0000001331 55.0
WLSH2_k127_9945949_3 - - - - 0.0002316 45.0
WLSH2_k127_9956843_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 306.0
WLSH2_k127_9956843_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000428 230.0
WLSH2_k127_9956843_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000001859 183.0
WLSH2_k127_9956843_3 Belongs to the UPF0178 family - - - 0.00000000000000000000000000000000000000236 150.0
WLSH2_k127_9956843_4 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.00000001026 57.0