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Overview

ID MAG04201
Name WLSH2_bin.22
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Elusimicrobiota
Class Elusimicrobia
Order FEN-1173
Family FEN-1173
Genus
Species
Assembly information
Completeness (%) 95.54
Contamination (%) 1.34
GC content (%) 62.0
N50 (bp) 20,186
Genome size (bp) 2,810,385

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2076

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10040705_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 403.0
WLSH2_k127_10040705_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 379.0
WLSH2_k127_10040705_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000317 246.0
WLSH2_k127_10040705_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000111 235.0
WLSH2_k127_10040705_4 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000001389 160.0
WLSH2_k127_10040705_5 Preprotein translocase subunit K03210 - - 0.0000000000000000000006318 100.0
WLSH2_k127_10040705_6 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000002327 83.0
WLSH2_k127_10040705_7 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000004838 70.0
WLSH2_k127_10040705_8 Protein involved in outer membrane biogenesis K07289 - - 0.0000009508 63.0
WLSH2_k127_10040705_9 PFAM AsmA family protein K07289 - - 0.000001253 62.0
WLSH2_k127_10121749_0 chalcone and stilbene synthase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000008881 224.0
WLSH2_k127_10121749_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000001486 134.0
WLSH2_k127_10121749_2 FAD binding domain - - - 0.000000000002378 78.0
WLSH2_k127_10121749_3 long-chain fatty acid transport protein - - - 0.00000000005674 72.0
WLSH2_k127_10152347_0 Domain of unknown function K03737 - 1.2.7.1 0.0 1624.0
WLSH2_k127_10152347_1 Sulfatase - - - 7.524e-308 953.0
WLSH2_k127_10152347_2 Flotillin K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 498.0
WLSH2_k127_10152347_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 389.0
WLSH2_k127_10152347_4 - - - - 0.000000000000101 78.0
WLSH2_k127_10152347_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0002425 44.0
WLSH2_k127_10152347_6 Protein conserved in bacteria - - - 0.0003371 47.0
WLSH2_k127_1022689_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 562.0
WLSH2_k127_1022689_1 hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000002387 212.0
WLSH2_k127_1022689_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000001387 198.0
WLSH2_k127_1022689_3 DNA polymerase III, delta' K02341 - 2.7.7.7 0.000000000000000000000000000000001089 147.0
WLSH2_k127_1022689_4 Addiction module toxin, RelE StbE family - - - 0.000000000000000000000002495 105.0
WLSH2_k127_1022689_5 - - - - 0.00000000004793 67.0
WLSH2_k127_1022689_6 Lysin motif - - - 0.0000002971 63.0
WLSH2_k127_1022689_8 Lamin Tail Domain - - - 0.0002027 56.0
WLSH2_k127_1022689_9 Bacterial Ig-like domain (group 1) - - - 0.0009996 53.0
WLSH2_k127_10262013_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000003009 267.0
WLSH2_k127_10262013_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000009425 251.0
WLSH2_k127_10262013_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000005325 141.0
WLSH2_k127_10262013_3 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000004169 56.0
WLSH2_k127_102633_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 568.0
WLSH2_k127_102633_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 416.0
WLSH2_k127_102633_10 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000009198 112.0
WLSH2_k127_102633_11 Ankyrin repeats (many copies) - - - 0.00000000000000001793 96.0
WLSH2_k127_102633_12 Methylmuconolactone methyl-isomerase - - - 0.00000000002227 70.0
WLSH2_k127_102633_13 Prokaryotic N-terminal methylation motif K02650,K02655 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000000006179 64.0
WLSH2_k127_102633_14 Predicted membrane protein (DUF2238) - - - 0.0000005456 59.0
WLSH2_k127_102633_15 domain protein - - - 0.000001619 61.0
WLSH2_k127_102633_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 339.0
WLSH2_k127_102633_3 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009251 277.0
WLSH2_k127_102633_4 Patatin-like phospholipase K01999,K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006736 285.0
WLSH2_k127_102633_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002591 270.0
WLSH2_k127_102633_6 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000005496 217.0
WLSH2_k127_102633_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000001129 210.0
WLSH2_k127_102633_8 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000001958 152.0
WLSH2_k127_102633_9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000003712 139.0
WLSH2_k127_10343193_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 369.0
WLSH2_k127_10343193_1 - - - - 0.0001453 53.0
WLSH2_k127_10510545_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.744e-203 662.0
WLSH2_k127_10510545_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 329.0
WLSH2_k127_10510545_2 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000101 253.0
WLSH2_k127_10510545_3 COGs COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM invasin domains) K08309 - - 0.00000000000000000000000000000174 127.0
WLSH2_k127_10510545_4 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000002579 102.0
WLSH2_k127_10510545_5 Belongs to the UPF0434 family K09791 - - 0.000000000000004133 82.0
WLSH2_k127_10692373_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 538.0
WLSH2_k127_10692373_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 381.0
WLSH2_k127_10692373_2 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000008737 269.0
WLSH2_k127_10692373_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004186 265.0
WLSH2_k127_10692373_4 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000005461 203.0
WLSH2_k127_10692373_5 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000003242 160.0
WLSH2_k127_10692373_6 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000005104 150.0
WLSH2_k127_10692373_7 Methyltransferase domain - - - 0.00000000000000000000000000000009126 133.0
WLSH2_k127_10692373_8 Methyltransferase domain - - - 0.00000000000000000000000000003925 132.0
WLSH2_k127_10692373_9 - - - - 0.0000000005587 72.0
WLSH2_k127_10783541_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 432.0
WLSH2_k127_10783541_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 326.0
WLSH2_k127_10783541_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004847 285.0
WLSH2_k127_10783541_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000002076 201.0
WLSH2_k127_10783541_5 outer membrane efflux protein - - - 0.00000001106 64.0
WLSH2_k127_10945164_0 chelatase, subunit ChlI K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 565.0
WLSH2_k127_10945164_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 411.0
WLSH2_k127_10945164_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 323.0
WLSH2_k127_10945164_3 Alkyl hydroperoxide reductase and or thiol-specific antioxidant family (AhpC TSA) protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 285.0
WLSH2_k127_10945164_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000003631 131.0
WLSH2_k127_10945164_5 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000597 79.0
WLSH2_k127_10945164_6 Cell division protein FtsJ - - - 0.000000000134 66.0
WLSH2_k127_10990017_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000462 310.0
WLSH2_k127_10990017_1 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000218 182.0
WLSH2_k127_10990017_2 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.0000000000000000000000000000000001411 155.0
WLSH2_k127_10990017_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000003066 78.0
WLSH2_k127_10990017_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000003822 63.0
WLSH2_k127_10990017_5 - - - - 0.0000002059 61.0
WLSH2_k127_10990017_6 Curli production assembly/transport component CsgG - - - 0.000002368 59.0
WLSH2_k127_10990017_7 COG0457 FOG TPR repeat - - - 0.000009512 55.0
WLSH2_k127_11105822_0 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 460.0
WLSH2_k127_11105822_1 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 422.0
WLSH2_k127_11105822_2 TIGRFAM alpha-L-glutamate ligase-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004415 249.0
WLSH2_k127_11105822_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000001613 145.0
WLSH2_k127_11105822_4 Universal stress protein - - - 0.00000005426 64.0
WLSH2_k127_11105822_5 ABC transporter, substrate-binding protein, family 5 K02035,K15580 - - 0.0006789 51.0
WLSH2_k127_11106070_0 PDZ domain (Also known as DHR K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 333.0
WLSH2_k127_11106070_1 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000006215 171.0
WLSH2_k127_11106070_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000001813 104.0
WLSH2_k127_111481_0 amino acid - - - 1.156e-207 668.0
WLSH2_k127_111481_1 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 599.0
WLSH2_k127_111481_10 Nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002385 248.0
WLSH2_k127_111481_11 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000929 166.0
WLSH2_k127_111481_12 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000003106 154.0
WLSH2_k127_111481_14 glutamine-fructose-6-phosphate transaminase (isomerizing) activity - - - 0.000000000000000000000000002626 132.0
WLSH2_k127_111481_15 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000005536 98.0
WLSH2_k127_111481_16 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000211 79.0
WLSH2_k127_111481_17 TonB C terminal K03832 - - 0.000003416 57.0
WLSH2_k127_111481_18 PFAM ABC transporter related K06148 - - 0.0001233 46.0
WLSH2_k127_111481_2 Cytochrome bd-type quinol oxidase subunit 1 K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 557.0
WLSH2_k127_111481_3 Carbon starvation protein K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 546.0
WLSH2_k127_111481_4 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 396.0
WLSH2_k127_111481_5 COG1294 Cytochrome bd-type quinol oxidase subunit 2 K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 374.0
WLSH2_k127_111481_6 SPFH domain / Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 359.0
WLSH2_k127_111481_7 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 349.0
WLSH2_k127_111481_8 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 341.0
WLSH2_k127_111481_9 PFAM Archaeal ATPase K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 297.0
WLSH2_k127_11167827_0 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005044 268.0
WLSH2_k127_11167827_1 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000002257 237.0
WLSH2_k127_11167827_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000001484 213.0
WLSH2_k127_11167827_3 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000087 164.0
WLSH2_k127_11167827_4 Periplasmic binding protein LacI transcriptional regulator - - - 0.00000000000000000000000000000000000000001635 166.0
WLSH2_k127_11167827_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000006371 140.0
WLSH2_k127_11167827_6 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration K05574 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000001171 113.0
WLSH2_k127_11167827_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000002236 119.0
WLSH2_k127_11167827_8 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.00000000000000000000000003022 113.0
WLSH2_k127_11167827_9 protein heterodimerization activity - - - 0.0002224 46.0
WLSH2_k127_11220229_0 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 493.0
WLSH2_k127_11220229_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 346.0
WLSH2_k127_11220229_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 344.0
WLSH2_k127_11220229_3 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 333.0
WLSH2_k127_11220229_4 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 303.0
WLSH2_k127_11220229_5 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001278 285.0
WLSH2_k127_11220229_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003145 285.0
WLSH2_k127_11220229_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000002547 123.0
WLSH2_k127_11227108_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000001031 204.0
WLSH2_k127_11227108_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000005655 169.0
WLSH2_k127_11231005_0 PFAM aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 473.0
WLSH2_k127_11231005_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 369.0
WLSH2_k127_11231005_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000006812 211.0
WLSH2_k127_11231005_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000002723 203.0
WLSH2_k127_11231005_4 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000168 154.0
WLSH2_k127_11231005_5 PFAM plasmid stabilization system K06218 - - 0.0000000000000000008653 89.0
WLSH2_k127_11231005_6 PFAM Protein kinase domain K05385,K12132,K13590 - 2.7.11.1,2.7.7.65 0.000000000000001432 91.0
WLSH2_k127_11231005_7 - - - - 0.0000000000001466 79.0
WLSH2_k127_11231005_8 - - - - 0.00000006016 57.0
WLSH2_k127_11241009_0 Transposase DDE domain group 1 - - - 0.0000000000000000000000000000000003435 147.0
WLSH2_k127_11378737_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 311.0
WLSH2_k127_11378737_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000002279 220.0
WLSH2_k127_11378737_2 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000001338 181.0
WLSH2_k127_11378737_3 Helix-hairpin-helix motif K02337,K14162 - 2.7.7.7 0.00000000000000000000000000001132 126.0
WLSH2_k127_11378737_4 membrane K08978 - - 0.000000000000000000000002271 109.0
WLSH2_k127_11378737_5 PFAM translation initiation factor SUI1 K03113 - - 0.0000000000000004687 80.0
WLSH2_k127_11378737_6 - - - - 0.000000004609 59.0
WLSH2_k127_11378737_7 Helix-turn-helix domain - - - 0.00000004626 58.0
WLSH2_k127_11439428_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 557.0
WLSH2_k127_11439428_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000002843 179.0
WLSH2_k127_11484175_0 chorismate binding enzyme K01665,K02619,K03342,K13503,K13950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 460.0
WLSH2_k127_11484175_1 ATPase (AAA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 433.0
WLSH2_k127_11484175_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 345.0
WLSH2_k127_11484175_3 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000005477 253.0
WLSH2_k127_11484175_4 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000007989 238.0
WLSH2_k127_11484175_6 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K07400 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - 0.00000000000000000000000001384 117.0
WLSH2_k127_11484175_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.00000000000000005472 87.0
WLSH2_k127_11484175_8 Periplasmic binding protein K02016 - - 0.000000006667 63.0
WLSH2_k127_11485577_0 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 304.0
WLSH2_k127_11485577_1 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000352 157.0
WLSH2_k127_11485577_2 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000008596 91.0
WLSH2_k127_11485577_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000005444 63.0
WLSH2_k127_11485577_4 long-chain fatty acid transport protein - - - 0.000008665 53.0
WLSH2_k127_11517367_0 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000000000000003112 239.0
WLSH2_k127_1268411_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 4.779e-196 629.0
WLSH2_k127_1268411_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001394 280.0
WLSH2_k127_1268411_2 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004234 226.0
WLSH2_k127_1268411_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000001 225.0
WLSH2_k127_1268411_4 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000002133 197.0
WLSH2_k127_1268411_5 TPR repeat - - - 0.000000000000000000000000000000000000000000000003057 188.0
WLSH2_k127_1268411_6 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000006524 157.0
WLSH2_k127_1268411_7 Tetratricopeptide repeat - - - 0.000000000005024 79.0
WLSH2_k127_1287043_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 485.0
WLSH2_k127_1287043_1 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000003121 271.0
WLSH2_k127_1287043_2 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000001237 91.0
WLSH2_k127_1287043_3 - - - - 0.000000000000000003197 93.0
WLSH2_k127_1287043_4 - - - - 0.0000002264 61.0
WLSH2_k127_1358113_0 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005002 281.0
WLSH2_k127_1358113_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000001489 116.0
WLSH2_k127_1358113_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000007063 107.0
WLSH2_k127_1358113_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000009179 96.0
WLSH2_k127_1358113_4 Tetratricopeptide repeat - - - 0.00000000000000000002201 106.0
WLSH2_k127_1408437_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 378.0
WLSH2_k127_1408437_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008495 278.0
WLSH2_k127_1408437_10 PFAM regulatory protein AsnC Lrp family - - - 0.0000008961 56.0
WLSH2_k127_1408437_11 permease K15771 GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - 0.000004001 54.0
WLSH2_k127_1408437_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004608 289.0
WLSH2_k127_1408437_3 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003321 263.0
WLSH2_k127_1408437_4 Zinc-uptake complex component A periplasmic K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001697 254.0
WLSH2_k127_1408437_5 Insulinase family (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000009723 236.0
WLSH2_k127_1408437_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000003715 214.0
WLSH2_k127_1408437_7 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000003918 188.0
WLSH2_k127_1408437_8 PFAM ABC transporter related K02013 - 3.6.3.34 0.00000000000000000000000000000000009877 143.0
WLSH2_k127_1408437_9 ABC 3 transport family K09819,K19976 - - 0.000000000000009763 85.0
WLSH2_k127_14238_0 Chaperone - - - 0.00006739 53.0
WLSH2_k127_1595432_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 333.0
WLSH2_k127_1595432_1 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007316 280.0
WLSH2_k127_1595432_2 ABC transporter permease K02025,K10193 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004834 285.0
WLSH2_k127_1595432_3 F5/8 type C domain - - - 0.000000000001593 79.0
WLSH2_k127_171200_0 Redoxin K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000006795 211.0
WLSH2_k127_171200_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000003608 115.0
WLSH2_k127_1729157_0 Glycogen debranching enzyme - - - 5.47e-312 965.0
WLSH2_k127_1729157_1 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 525.0
WLSH2_k127_1729157_2 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 418.0
WLSH2_k127_1729157_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001385 181.0
WLSH2_k127_1729157_4 Protein of unknown function (DUF1778) - - - 0.00000000000000000000000003413 110.0
WLSH2_k127_1781294_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 487.0
WLSH2_k127_1781294_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 308.0
WLSH2_k127_1781294_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000111 242.0
WLSH2_k127_1781294_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000006843 213.0
WLSH2_k127_1822689_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 591.0
WLSH2_k127_1822689_1 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 347.0
WLSH2_k127_1822689_2 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000001078 181.0
WLSH2_k127_1822689_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000003218 138.0
WLSH2_k127_1822689_5 - K07283 - - 0.00000000000001544 83.0
WLSH2_k127_1844451_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 9.306e-212 674.0
WLSH2_k127_1844451_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 306.0
WLSH2_k127_1844451_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001991 250.0
WLSH2_k127_1844451_3 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000193 211.0
WLSH2_k127_1844451_4 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000001837 191.0
WLSH2_k127_1844451_5 Flavin containing amine oxidoreductase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000004996 199.0
WLSH2_k127_1844451_6 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000006078 169.0
WLSH2_k127_1844451_7 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000001246 158.0
WLSH2_k127_1844451_8 Belongs to the peptidase S8 family - - - 0.0001904 53.0
WLSH2_k127_1885789_0 Sulfatase K01130 - 3.1.6.1 0.0 1142.0
WLSH2_k127_1885789_1 Belongs to the GPI family K01810 - 5.3.1.9 5.652e-274 851.0
WLSH2_k127_1885789_10 - - - - 0.000000000000000000000000000000000000000000000000000007959 214.0
WLSH2_k127_1885789_11 - - - - 0.000000000000000000000000000000000000000000000000003353 197.0
WLSH2_k127_1885789_12 - - - - 0.00000000000000000000000000000000000000000000001839 190.0
WLSH2_k127_1885789_13 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000007285 190.0
WLSH2_k127_1885789_14 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000006927 157.0
WLSH2_k127_1885789_15 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000005777 141.0
WLSH2_k127_1885789_16 nucleotidyltransferase activity - - - 0.000000000000000000000000000000003465 132.0
WLSH2_k127_1885789_17 Endoglucanase K01218 - 3.2.1.78 0.0000000000000000000001197 116.0
WLSH2_k127_1885789_18 - - - - 0.0000000000000000000001439 109.0
WLSH2_k127_1885789_19 Nucleotidyltransferase domain - - - 0.0000000000000002211 82.0
WLSH2_k127_1885789_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K04085 - - 1.285e-258 809.0
WLSH2_k127_1885789_20 - - - - 0.000000000000006183 88.0
WLSH2_k127_1885789_21 Fibronectin type III - - - 0.00000000000006164 87.0
WLSH2_k127_1885789_22 chitin catabolic process K01183,K03933,K13381 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.14,3.2.1.17 0.000000000002702 75.0
WLSH2_k127_1885789_23 - - - - 0.0000005795 61.0
WLSH2_k127_1885789_24 metallopeptidase activity - - - 0.00002511 55.0
WLSH2_k127_1885789_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 1.14e-233 733.0
WLSH2_k127_1885789_4 radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 529.0
WLSH2_k127_1885789_5 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 464.0
WLSH2_k127_1885789_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 301.0
WLSH2_k127_1885789_7 TspO MBR family protein K05770 - - 0.000000000000000000000000000000000000000000000000000000000000000000644 232.0
WLSH2_k127_1885789_8 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000006653 216.0
WLSH2_k127_1885789_9 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.0000000000000000000000000000000000000000000000000000000002002 207.0
WLSH2_k127_1933152_0 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002506 253.0
WLSH2_k127_1933152_2 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000002079 55.0
WLSH2_k127_1974753_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1088.0
WLSH2_k127_1974753_1 PFAM peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 3.228e-196 639.0
WLSH2_k127_1974753_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 366.0
WLSH2_k127_1974753_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 358.0
WLSH2_k127_1974753_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000007186 166.0
WLSH2_k127_1974753_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000007831 143.0
WLSH2_k127_2046114_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity - - - 0.0 1090.0
WLSH2_k127_2046114_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 518.0
WLSH2_k127_2046114_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001604 286.0
WLSH2_k127_2046114_3 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002582 278.0
WLSH2_k127_2046114_4 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000002669 160.0
WLSH2_k127_2046114_5 Crp-like helix-turn-helix domain K10914 - - 0.0000000000000006455 87.0
WLSH2_k127_2046114_6 Cro/C1-type HTH DNA-binding domain - - - 0.000009178 50.0
WLSH2_k127_2068955_0 ATPase (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 545.0
WLSH2_k127_2068955_1 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 454.0
WLSH2_k127_2068955_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 337.0
WLSH2_k127_2068955_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000001421 202.0
WLSH2_k127_2068955_4 COGs COG0317 Guanosine polyphosphate pyrophosphohydrolase synthetase K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000002962 194.0
WLSH2_k127_2068955_5 - - - - 0.0000000000000000000000000000000000002862 148.0
WLSH2_k127_2068955_6 - - - - 0.000000000000000000000008102 115.0
WLSH2_k127_2068955_7 membrane - - - 0.0000000000002245 74.0
WLSH2_k127_2068955_8 DNA mediated transformation K04096 - - 0.000000000000318 73.0
WLSH2_k127_2068955_9 SMART Chromosomal replication initiator DnaA domain - - - 0.00000001079 58.0
WLSH2_k127_2093230_0 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 442.0
WLSH2_k127_2093230_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 304.0
WLSH2_k127_2093230_2 PFAM CoA-binding domain protein K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 290.0
WLSH2_k127_2093230_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000002088 222.0
WLSH2_k127_2093230_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000001077 168.0
WLSH2_k127_2093230_5 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000001239 136.0
WLSH2_k127_2093230_6 Ribosomal protein L17 K02879 - - 0.00000000000000000000006606 107.0
WLSH2_k127_2093230_7 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000006994 94.0
WLSH2_k127_2093230_8 Rod shape-determining protein (MreD) K03571 - - 0.0001012 54.0
WLSH2_k127_2131562_0 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 561.0
WLSH2_k127_2131562_1 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000003379 187.0
WLSH2_k127_2131562_2 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.00000000000005042 85.0
WLSH2_k127_2131562_3 - - - - 0.00000000001948 77.0
WLSH2_k127_2131562_4 - - - - 0.00002362 56.0
WLSH2_k127_2131562_5 chitin catabolic process K01183,K03933,K13381 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.14,3.2.1.17 0.0001136 52.0
WLSH2_k127_2154271_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 4.405e-215 678.0
WLSH2_k127_2154271_1 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 512.0
WLSH2_k127_2154271_10 - - - - 0.0000000000000000000000000000000000000001679 164.0
WLSH2_k127_2154271_11 PFAM metal-dependent phosphohydrolase, HD sub domain K02030,K02103,K02529 - - 0.000000000000000000000000000000000000002838 158.0
WLSH2_k127_2154271_12 Protein of unknown function (DUF2490) - - - 0.00000000000000000002069 100.0
WLSH2_k127_2154271_13 metallopeptidase activity - - - 0.00000000000000002818 93.0
WLSH2_k127_2154271_14 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000006668 93.0
WLSH2_k127_2154271_15 long-chain fatty acid transport protein - - - 0.000000000001865 78.0
WLSH2_k127_2154271_16 long-chain fatty acid transporting porin activity - - - 0.000000000002299 78.0
WLSH2_k127_2154271_17 penicillin-binding protein - - - 0.0000000001409 72.0
WLSH2_k127_2154271_18 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000004404 60.0
WLSH2_k127_2154271_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 490.0
WLSH2_k127_2154271_3 Domain of unknown function (DUF4172) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 474.0
WLSH2_k127_2154271_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 467.0
WLSH2_k127_2154271_5 Belongs to the glutaminase family K01425 - 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 422.0
WLSH2_k127_2154271_6 Protein conserved in bacteria K11891,K11902,K11910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 362.0
WLSH2_k127_2154271_7 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000003122 204.0
WLSH2_k127_2154271_8 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000000000006658 186.0
WLSH2_k127_2154271_9 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.0000000000000000000000000000000000000000000000001061 190.0
WLSH2_k127_2197906_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 325.0
WLSH2_k127_2197906_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000001365 233.0
WLSH2_k127_2197906_2 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000001459 205.0
WLSH2_k127_2197906_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000007808 200.0
WLSH2_k127_2197906_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000001726 195.0
WLSH2_k127_2197906_5 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000003337 118.0
WLSH2_k127_2197906_6 Belongs to the UPF0235 family K09131 - - 0.00000000000005015 76.0
WLSH2_k127_2197906_7 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - 0.0000000000001222 81.0
WLSH2_k127_2197906_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000002195 65.0
WLSH2_k127_2197906_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000001783 69.0
WLSH2_k127_2325603_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 5.289e-257 805.0
WLSH2_k127_2325603_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.628e-207 678.0
WLSH2_k127_2325603_10 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000005237 97.0
WLSH2_k127_2325603_11 COGs COG3377 conserved - - - 0.00000000000000003668 84.0
WLSH2_k127_2325603_12 phytol kinase activity K16368 GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006629,GO:0006644,GO:0006650,GO:0006654,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046473,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0098827,GO:1901576 2.7.1.174 0.000000000002895 78.0
WLSH2_k127_2325603_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000001604 70.0
WLSH2_k127_2325603_14 helix_turn_helix, mercury resistance K03713,K15580 GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - 0.00000000002079 68.0
WLSH2_k127_2325603_15 - - - - 0.0000000006822 70.0
WLSH2_k127_2325603_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 343.0
WLSH2_k127_2325603_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 311.0
WLSH2_k127_2325603_4 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 291.0
WLSH2_k127_2325603_5 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006579 298.0
WLSH2_k127_2325603_6 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000001626 152.0
WLSH2_k127_2325603_7 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000001047 153.0
WLSH2_k127_2325603_8 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000000000001774 124.0
WLSH2_k127_2325603_9 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000000000000000000001357 117.0
WLSH2_k127_2432214_0 Glycogen debranching enzyme - - - 0.0 1302.0
WLSH2_k127_2432214_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K04085 - - 4.246e-253 796.0
WLSH2_k127_2432214_10 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001976 279.0
WLSH2_k127_2432214_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000000000000000000000000000006612 220.0
WLSH2_k127_2432214_12 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000006734 203.0
WLSH2_k127_2432214_13 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.000000000000000000000000000000000000000000000001265 180.0
WLSH2_k127_2432214_14 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000003831 175.0
WLSH2_k127_2432214_15 - - - - 0.000000000000000000000000000000000000000000009796 174.0
WLSH2_k127_2432214_17 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000008121 129.0
WLSH2_k127_2432214_18 hydroperoxide reductase activity - - - 0.00000000000000000000000000057 119.0
WLSH2_k127_2432214_2 alpha amylase, catalytic region - - - 1.462e-216 682.0
WLSH2_k127_2432214_20 acr, cog1430 K09005 - - 0.0000000000000000000002358 103.0
WLSH2_k127_2432214_21 - - - - 0.00000000000000002206 90.0
WLSH2_k127_2432214_22 - - - - 0.00000000000000009703 86.0
WLSH2_k127_2432214_23 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.00000000005309 71.0
WLSH2_k127_2432214_3 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 529.0
WLSH2_k127_2432214_4 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 464.0
WLSH2_k127_2432214_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 403.0
WLSH2_k127_2432214_6 Phospholipase D. Active site motifs. K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 350.0
WLSH2_k127_2432214_7 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 327.0
WLSH2_k127_2432214_8 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 313.0
WLSH2_k127_2432214_9 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 303.0
WLSH2_k127_2445565_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 504.0
WLSH2_k127_2445565_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 467.0
WLSH2_k127_2445565_2 GPI anchored protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002331 286.0
WLSH2_k127_2445565_3 PIN domain - - - 0.00000000000000000000000000000000000002387 148.0
WLSH2_k127_2445565_4 - - - - 0.0000000000003038 72.0
WLSH2_k127_2445565_5 coagulation factor 5 8 type - - - 0.000003566 55.0
WLSH2_k127_2445565_6 Ami_3 K01448 - 3.5.1.28 0.000004889 63.0
WLSH2_k127_2477507_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 408.0
WLSH2_k127_2477507_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 345.0
WLSH2_k127_2477507_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 289.0
WLSH2_k127_2493085_0 RHS Repeat - - - 0.0000004694 65.0
WLSH2_k127_2545220_0 Iron hydrogenase small subunit K00336,K18006 - 1.12.1.2,1.6.5.3 8.144e-269 838.0
WLSH2_k127_2545220_1 NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit K00335,K18331 - 1.12.1.3,1.6.5.3 1.475e-201 640.0
WLSH2_k127_2545220_10 TIGRFAM Hydrogenase expression formation protein K03605 - - 0.000000000000000001158 95.0
WLSH2_k127_2545220_2 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 547.0
WLSH2_k127_2545220_3 PFAM Nickel-dependent hydrogenase, large subunit K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 452.0
WLSH2_k127_2545220_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003384 268.0
WLSH2_k127_2545220_5 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000006103 235.0
WLSH2_k127_2545220_6 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000289 229.0
WLSH2_k127_2545220_7 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000001396 195.0
WLSH2_k127_2545220_8 Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000002241 188.0
WLSH2_k127_2545220_9 nickel cation binding K04651 - - 0.00000000000000000000000005787 111.0
WLSH2_k127_2548896_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 426.0
WLSH2_k127_2548896_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 302.0
WLSH2_k127_2548896_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000001088 203.0
WLSH2_k127_2548896_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.000000000000000000000000000000005286 134.0
WLSH2_k127_2548896_4 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000005871 126.0
WLSH2_k127_2548896_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000005843 112.0
WLSH2_k127_2548896_6 - - - - 0.00000004992 58.0
WLSH2_k127_2548896_7 - - - - 0.00006785 48.0
WLSH2_k127_2549332_0 TIGRFAM glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 375.0
WLSH2_k127_2549332_1 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 306.0
WLSH2_k127_2549332_2 Protein of unknown function (DUF819) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001014 247.0
WLSH2_k127_2549332_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000003654 189.0
WLSH2_k127_2549332_4 PFAM Mandelate racemase muconate lactonizing - GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000004603 192.0
WLSH2_k127_2549332_5 cysteine-type peptidase activity K20742,K21471 - 3.4.14.13 0.0000000000000000000000000000000000000000008893 175.0
WLSH2_k127_2549332_6 Helix-turn-helix XRE-family like proteins - - - 0.000000000182 72.0
WLSH2_k127_2591623_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000001948 231.0
WLSH2_k127_2591623_1 protein conserved in bacteria K09973 - - 0.00000000000000002958 94.0
WLSH2_k127_2591623_2 SUPERFAMILY SSF53098, Polynucleotidyl transferase, Ribonuclease H fold - - - 0.0000000001466 67.0
WLSH2_k127_2591623_3 Pkd domain containing protein - - - 0.0000000006983 72.0
WLSH2_k127_2593683_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 437.0
WLSH2_k127_2593683_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 336.0
WLSH2_k127_2593683_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 292.0
WLSH2_k127_2593683_3 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 293.0
WLSH2_k127_2593683_4 COGs COG0683 ABC-type branched-chain amino acid transport systems periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009334 303.0
WLSH2_k127_2593683_5 Two component transcriptional regulator, winged helix family K07657 - - 0.000000000000000000000000000000000000000000000209 177.0
WLSH2_k127_2593683_6 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000004137 184.0
WLSH2_k127_2593683_7 peptidase K21471 - - 0.00000000000000000000000002323 117.0
WLSH2_k127_2593683_8 alginic acid biosynthetic process K20276 - - 0.00000000001362 79.0
WLSH2_k127_2595161_0 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000001222 115.0
WLSH2_k127_2597801_0 - K06921 - - 0.000000000000000000000000000000000000000000000000006625 198.0
WLSH2_k127_2597801_1 3'-5' exonuclease - - - 0.00000000000000000000000000000000000000000000000002185 188.0
WLSH2_k127_271856_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 2.988e-224 704.0
WLSH2_k127_271856_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.871e-221 692.0
WLSH2_k127_271856_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000003168 239.0
WLSH2_k127_271856_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000001596 173.0
WLSH2_k127_271856_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000003966 111.0
WLSH2_k127_271856_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000004544 89.0
WLSH2_k127_271856_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000005803 88.0
WLSH2_k127_271856_7 overlaps another CDS with the same product name - - - 0.0000000006386 70.0
WLSH2_k127_271856_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000001837 65.0
WLSH2_k127_271856_9 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0005206 47.0
WLSH2_k127_2753465_0 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 438.0
WLSH2_k127_2753465_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 367.0
WLSH2_k127_2753465_10 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000005015 76.0
WLSH2_k127_2753465_2 LytB protein K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 349.0
WLSH2_k127_2753465_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001018 253.0
WLSH2_k127_2753465_4 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000005292 215.0
WLSH2_k127_2753465_5 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000119 194.0
WLSH2_k127_2753465_6 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000003438 171.0
WLSH2_k127_2753465_7 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000001083 162.0
WLSH2_k127_2753465_8 - - - - 0.00000000000000000000000125 113.0
WLSH2_k127_2753465_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000001057 79.0
WLSH2_k127_2769633_0 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002706 282.0
WLSH2_k127_2769633_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000002407 64.0
WLSH2_k127_2774004_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 531.0
WLSH2_k127_2774004_1 Peptidase, M20 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 321.0
WLSH2_k127_2774004_10 Glycosyl transferases group 1 K02844 - - 0.00000000000000000000004412 112.0
WLSH2_k127_2774004_11 Histidine kinase K10681 - 2.7.13.3 0.000000000000000000002099 110.0
WLSH2_k127_2774004_12 glycoprotease K01409,K14742 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000372 100.0
WLSH2_k127_2774004_13 HAMP domain - - - 0.00000000000000000005877 105.0
WLSH2_k127_2774004_14 His Kinase A (phosphoacceptor) domain - - - 0.000000002353 65.0
WLSH2_k127_2774004_15 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000008931 60.0
WLSH2_k127_2774004_16 PFAM outer membrane efflux protein - - - 0.000002524 60.0
WLSH2_k127_2774004_17 nucleotidyltransferase activity K07076 - - 0.000002799 53.0
WLSH2_k127_2774004_18 - - - - 0.0001671 49.0
WLSH2_k127_2774004_19 tail collar domain protein - - - 0.0002058 53.0
WLSH2_k127_2774004_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 314.0
WLSH2_k127_2774004_20 positive regulation of growth - - - 0.0003248 47.0
WLSH2_k127_2774004_3 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000003303 216.0
WLSH2_k127_2774004_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000008879 200.0
WLSH2_k127_2774004_5 PFAM ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.000000000000000000000000000000000007346 156.0
WLSH2_k127_2774004_6 PhoQ Sensor - - - 0.00000000000000000000000000000000001261 156.0
WLSH2_k127_2774004_7 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000153 134.0
WLSH2_k127_2774004_8 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.00000000000000000000000231 109.0
WLSH2_k127_2774004_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.00000000000000000000002644 113.0
WLSH2_k127_2848458_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.976e-207 673.0
WLSH2_k127_2848458_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 337.0
WLSH2_k127_2848458_2 pyridine nucleotide-disulfide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 314.0
WLSH2_k127_2848458_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001692 269.0
WLSH2_k127_2848458_4 - - - - 0.000000005416 70.0
WLSH2_k127_2851717_0 Putative sugar-binding N-terminal domain K22129 - 2.7.1.219,2.7.1.220 0.00000000000000000000000000000000000000003382 168.0
WLSH2_k127_2851717_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000001545 164.0
WLSH2_k127_2851717_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000001038 124.0
WLSH2_k127_2851717_3 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000005144 104.0
WLSH2_k127_286029_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000001837 73.0
WLSH2_k127_286029_1 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000008747 78.0
WLSH2_k127_286029_2 Glycosyl hydrolase family 57 - - - 0.00000000002658 77.0
WLSH2_k127_2893675_0 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000001978 205.0
WLSH2_k127_2893675_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000001683 119.0
WLSH2_k127_2955470_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.132e-232 734.0
WLSH2_k127_2955470_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 424.0
WLSH2_k127_2955470_10 SpoIID LytB domain protein K06381 - - 0.000000000000000000000000000000000000000000000000000005426 214.0
WLSH2_k127_2955470_11 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000004629 173.0
WLSH2_k127_2955470_12 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000007475 127.0
WLSH2_k127_2955470_13 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000009486 111.0
WLSH2_k127_2955470_14 Plasmid maintenance system killer K07334 - - 0.00000000000000000000000001052 112.0
WLSH2_k127_2955470_15 Domain of unknown function (DUF4160) - - - 0.000000000000000000000004816 106.0
WLSH2_k127_2955470_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000006513 111.0
WLSH2_k127_2955470_17 Protein of unknown function (DUF2442) - - - 0.000000000000000000001119 97.0
WLSH2_k127_2955470_18 CBS domain - - - 0.00000000000000000003846 96.0
WLSH2_k127_2955470_19 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.00000000000001133 83.0
WLSH2_k127_2955470_2 ATPase (AAA superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 414.0
WLSH2_k127_2955470_20 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000006335 73.0
WLSH2_k127_2955470_21 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.00005331 60.0
WLSH2_k127_2955470_22 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0002097 58.0
WLSH2_k127_2955470_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 409.0
WLSH2_k127_2955470_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 391.0
WLSH2_k127_2955470_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 379.0
WLSH2_k127_2955470_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 370.0
WLSH2_k127_2955470_7 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 326.0
WLSH2_k127_2955470_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 300.0
WLSH2_k127_2955470_9 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 289.0
WLSH2_k127_2980541_0 Type I restriction enzyme R protein N terminus (HSDR_N) K01153 - 3.1.21.3 0.0 1480.0
WLSH2_k127_2980541_1 transcriptional regulator K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 552.0
WLSH2_k127_2980541_2 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 301.0
WLSH2_k127_2980541_3 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006964 273.0
WLSH2_k127_2980541_4 PFAM restriction modification system DNA specificity domain K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000001294 216.0
WLSH2_k127_2980541_5 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000744 173.0
WLSH2_k127_2980541_6 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000000003109 94.0
WLSH2_k127_2980541_7 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0006089 44.0
WLSH2_k127_2980545_0 Protein of unknown function (DUF499) K06922 - - 0.0 1495.0
WLSH2_k127_2980545_1 Protein of unknown function (DUF1156) K07445 - - 1.065e-293 914.0
WLSH2_k127_2980545_2 DNA methylAse K07445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 499.0
WLSH2_k127_2980545_3 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 295.0
WLSH2_k127_2980545_4 Divergent AAA domain protein K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000005833 184.0
WLSH2_k127_2990993_0 magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase K04034 GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 427.0
WLSH2_k127_2990993_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 342.0
WLSH2_k127_2990993_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 289.0
WLSH2_k127_2990993_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001272 294.0
WLSH2_k127_2990993_4 polysaccharide biosynthetic process K19431 - - 0.000000000000000000006119 107.0
WLSH2_k127_2990993_5 PFAM Methyltransferase type - - - 0.00000000001133 74.0
WLSH2_k127_2990993_6 Methyltransferase domain K00588 - 2.1.1.104 0.0006958 50.0
WLSH2_k127_3031830_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000105 256.0
WLSH2_k127_3031830_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000002689 87.0
WLSH2_k127_3035336_0 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 466.0
WLSH2_k127_3035336_1 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000336 290.0
WLSH2_k127_3035336_2 PLD-like domain - - - 0.00000000000001221 87.0
WLSH2_k127_3035336_3 Domain of unknown function (DUF4172) - - - 0.0000000000001241 71.0
WLSH2_k127_3035336_4 - - - - 0.000000127 64.0
WLSH2_k127_3083038_0 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 395.0
WLSH2_k127_3083038_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 378.0
WLSH2_k127_3083038_2 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000009123 138.0
WLSH2_k127_3083038_3 response regulator K02657 - - 0.0000000000000007482 83.0
WLSH2_k127_3091487_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 466.0
WLSH2_k127_3091487_1 NeuB family K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 409.0
WLSH2_k127_3091487_2 PFAM Thermolysin metallopeptidase, alpha-helical domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 379.0
WLSH2_k127_3091487_3 PFAM acylneuraminate cytidylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002279 245.0
WLSH2_k127_3091487_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000005572 213.0
WLSH2_k127_3091487_5 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.000000000000000000000000000000000000000000000000000002805 204.0
WLSH2_k127_3091487_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000001885 161.0
WLSH2_k127_3091487_7 Cytidylyltransferase K03270 - 3.1.3.45 0.0000000000000000008601 92.0
WLSH2_k127_3202307_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 404.0
WLSH2_k127_3202307_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 318.0
WLSH2_k127_3202307_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000001846 237.0
WLSH2_k127_3202307_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000385 199.0
WLSH2_k127_3202307_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000004439 66.0
WLSH2_k127_3202307_5 Tetratricopeptide repeat - - - 0.00009197 52.0
WLSH2_k127_3219177_0 Pectate lyase superfamily protein - - - 0.00000000000000000000000000000000000000000000000000000000000000524 238.0
WLSH2_k127_322533_0 Large extracellular alpha-helical protein K06894 - - 0.0 1979.0
WLSH2_k127_322533_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1161.0
WLSH2_k127_322533_10 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004619 283.0
WLSH2_k127_322533_11 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001394 274.0
WLSH2_k127_322533_12 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002848 242.0
WLSH2_k127_322533_13 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000007443 246.0
WLSH2_k127_322533_14 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000000000000000000732 189.0
WLSH2_k127_322533_15 Beta-propeller repeat - - - 0.00000000000000000000000000000000000000000001809 188.0
WLSH2_k127_322533_16 PFAM Class I peptide chain release factor - - - 0.0000000000000000000000000000005845 128.0
WLSH2_k127_322533_17 - - - - 0.000000000000000000000005814 111.0
WLSH2_k127_322533_18 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000006618 120.0
WLSH2_k127_322533_19 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000001176 104.0
WLSH2_k127_322533_2 ABC-type uncharacterized transport system K01992 - - 0.0 1095.0
WLSH2_k127_322533_20 - - - - 0.0000001514 64.0
WLSH2_k127_322533_21 Appr-1-p processing domain protein - - - 0.000001564 59.0
WLSH2_k127_322533_3 Alpha amylase, catalytic domain K01176 - 3.2.1.1 4.37e-294 914.0
WLSH2_k127_322533_4 Conserved region in glutamate synthase - - - 3.549e-278 865.0
WLSH2_k127_322533_5 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 550.0
WLSH2_k127_322533_6 Pyridine nucleotide-disulphide oxidoreductase K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 412.0
WLSH2_k127_322533_7 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 383.0
WLSH2_k127_322533_8 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 348.0
WLSH2_k127_322533_9 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 343.0
WLSH2_k127_3319255_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.181e-205 667.0
WLSH2_k127_3319255_1 N-4 methylation of cytosine K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 512.0
WLSH2_k127_3319255_10 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005051 271.0
WLSH2_k127_3319255_11 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001129 270.0
WLSH2_k127_3319255_12 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000001922 235.0
WLSH2_k127_3319255_13 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000002353 245.0
WLSH2_k127_3319255_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000004976 195.0
WLSH2_k127_3319255_15 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000141 185.0
WLSH2_k127_3319255_16 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000002138 168.0
WLSH2_k127_3319255_17 - - - - 0.00000000000000000000000000000000000000007411 156.0
WLSH2_k127_3319255_18 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000009791 161.0
WLSH2_k127_3319255_19 PhoQ Sensor - - - 0.0000000000000000000000000000000000000001098 163.0
WLSH2_k127_3319255_2 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 487.0
WLSH2_k127_3319255_20 ggdef domain - - - 0.000000000000000000000000000000000001048 155.0
WLSH2_k127_3319255_21 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000001403 137.0
WLSH2_k127_3319255_22 CHAD - - - 0.000000000000000000000000000008255 130.0
WLSH2_k127_3319255_23 - - - - 0.0000000000000000000000000189 116.0
WLSH2_k127_3319255_24 Phosphoglycerate mutase family K03574 - 3.6.1.55 0.00001113 57.0
WLSH2_k127_3319255_3 TIGRFAM phosphate binding protein K02040 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 443.0
WLSH2_k127_3319255_4 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 439.0
WLSH2_k127_3319255_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 410.0
WLSH2_k127_3319255_6 Monogalactosyldiacylglycerol synthase, C-terminal domain protein K03429 - 2.4.1.315 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 406.0
WLSH2_k127_3319255_7 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 402.0
WLSH2_k127_3319255_8 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 370.0
WLSH2_k127_3319255_9 Belongs to the pirin family K06911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002382 280.0
WLSH2_k127_3322193_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 9.008e-223 721.0
WLSH2_k127_3322193_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 588.0
WLSH2_k127_3322193_10 ABC transporter K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 399.0
WLSH2_k127_3322193_11 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 392.0
WLSH2_k127_3322193_12 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 364.0
WLSH2_k127_3322193_13 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 349.0
WLSH2_k127_3322193_14 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 315.0
WLSH2_k127_3322193_15 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 310.0
WLSH2_k127_3322193_16 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 297.0
WLSH2_k127_3322193_17 Elongator protein 3, MiaB family, Radical SAM K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003671 281.0
WLSH2_k127_3322193_18 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000007939 240.0
WLSH2_k127_3322193_19 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000004782 220.0
WLSH2_k127_3322193_2 cytochrome c - GO:0005575,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017004,GO:0022607,GO:0031224,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0065003,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 586.0
WLSH2_k127_3322193_20 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000003543 225.0
WLSH2_k127_3322193_21 Secondary thiamine-phosphate synthase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000001733 208.0
WLSH2_k127_3322193_22 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000001211 218.0
WLSH2_k127_3322193_23 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000002549 203.0
WLSH2_k127_3322193_24 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000001972 192.0
WLSH2_k127_3322193_25 PFAM cytochrome B561 - - - 0.0000000000000000000000000000000000000000000000000149 191.0
WLSH2_k127_3322193_26 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000001279 190.0
WLSH2_k127_3322193_27 Polypeptide deformylase K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000001692 169.0
WLSH2_k127_3322193_28 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000009692 168.0
WLSH2_k127_3322193_29 iron-sulfur cluster assembly - - - 0.0000000000000000000000000000000000000000001594 165.0
WLSH2_k127_3322193_3 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 541.0
WLSH2_k127_3322193_30 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000001476 172.0
WLSH2_k127_3322193_31 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000003371 161.0
WLSH2_k127_3322193_32 diguanylate cyclase - - - 0.000000000000000000000000000000000000002702 164.0
WLSH2_k127_3322193_33 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000002925 142.0
WLSH2_k127_3322193_35 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000001607 154.0
WLSH2_k127_3322193_36 heat shock protein binding - - - 0.000000000000000000000000000001964 134.0
WLSH2_k127_3322193_37 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000005055 126.0
WLSH2_k127_3322193_38 regulation of RNA biosynthetic process K03567 - - 0.0000000000000000000000000006976 121.0
WLSH2_k127_3322193_39 - - - - 0.0000000000000000000000000009212 122.0
WLSH2_k127_3322193_4 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 541.0
WLSH2_k127_3322193_40 diguanylate cyclase - - - 0.000000000000000000000000001541 128.0
WLSH2_k127_3322193_41 Binds the 23S rRNA K02909 - - 0.0000000000000000000000404 106.0
WLSH2_k127_3322193_42 PFAM VanZ family protein - - - 0.0000000000000004524 85.0
WLSH2_k127_3322193_43 - - - - 0.0000000000002516 74.0
WLSH2_k127_3322193_44 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000001341 69.0
WLSH2_k127_3322193_45 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000003287 64.0
WLSH2_k127_3322193_46 - - - - 0.0001485 52.0
WLSH2_k127_3322193_5 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 516.0
WLSH2_k127_3322193_6 Cytochrome c bacterial - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 467.0
WLSH2_k127_3322193_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 428.0
WLSH2_k127_3322193_8 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 433.0
WLSH2_k127_3322193_9 Protein of unknown function (DUF3373) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 403.0
WLSH2_k127_3355925_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0 1282.0
WLSH2_k127_3355925_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.90 5.344e-213 676.0
WLSH2_k127_3355925_10 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 323.0
WLSH2_k127_3355925_11 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 319.0
WLSH2_k127_3355925_12 RibD C-terminal domain K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 302.0
WLSH2_k127_3355925_13 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004706 301.0
WLSH2_k127_3355925_14 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001855 260.0
WLSH2_k127_3355925_15 Iron-sulfur cluster-binding domain K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000006162 234.0
WLSH2_k127_3355925_16 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000001601 210.0
WLSH2_k127_3355925_17 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000001717 212.0
WLSH2_k127_3355925_18 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000002088 211.0
WLSH2_k127_3355925_19 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000001456 198.0
WLSH2_k127_3355925_2 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 547.0
WLSH2_k127_3355925_20 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000003848 187.0
WLSH2_k127_3355925_21 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000003493 182.0
WLSH2_k127_3355925_22 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000007268 146.0
WLSH2_k127_3355925_23 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000000000001999 142.0
WLSH2_k127_3355925_24 response regulator K07668,K07775 - - 0.0000000000000000000000000000000164 130.0
WLSH2_k127_3355925_25 manually curated - - - 0.0000000000000000000000000000001148 125.0
WLSH2_k127_3355925_26 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000002708 120.0
WLSH2_k127_3355925_27 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000009746 130.0
WLSH2_k127_3355925_28 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000003098 120.0
WLSH2_k127_3355925_29 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000003374 122.0
WLSH2_k127_3355925_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 518.0
WLSH2_k127_3355925_30 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.000000000000000000000002997 109.0
WLSH2_k127_3355925_31 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000002062 108.0
WLSH2_k127_3355925_32 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000004613 109.0
WLSH2_k127_3355925_33 - - - - 0.0000000000001138 72.0
WLSH2_k127_3355925_34 - - - - 0.0000000000005499 76.0
WLSH2_k127_3355925_35 Prokaryotic N-terminal methylation motif - - - 0.000000000005092 72.0
WLSH2_k127_3355925_36 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000004445 66.0
WLSH2_k127_3355925_37 - - - - 0.0000000001567 70.0
WLSH2_k127_3355925_38 - - - - 0.000000003511 67.0
WLSH2_k127_3355925_39 AsmA-like C-terminal region - - - 0.00001891 58.0
WLSH2_k127_3355925_4 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 472.0
WLSH2_k127_3355925_40 Zinc ribbon domain K07164 - - 0.00004439 54.0
WLSH2_k127_3355925_5 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 461.0
WLSH2_k127_3355925_6 ATPase (AAA superfamily K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 453.0
WLSH2_k127_3355925_7 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 437.0
WLSH2_k127_3355925_8 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 382.0
WLSH2_k127_3355925_9 Sigma-70 factor, region 1.1 K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 366.0
WLSH2_k127_337845_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 8.506e-279 894.0
WLSH2_k127_337845_1 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 612.0
WLSH2_k127_337845_10 Uncharacterized conserved protein (DUF2183) - - - 0.00000000000000000000000000000000000000000000000000000000003641 218.0
WLSH2_k127_337845_11 FusA NodT family protein - - - 0.0000000000000000000000000000000000000000000000000000000001369 220.0
WLSH2_k127_337845_12 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000001759 203.0
WLSH2_k127_337845_13 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000003314 171.0
WLSH2_k127_337845_14 PFAM short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.000000000000000000000000000000000000001682 156.0
WLSH2_k127_337845_15 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000000003497 130.0
WLSH2_k127_337845_16 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000001229 125.0
WLSH2_k127_337845_17 Sigma-70 region 2 K03088 - - 0.00000000000000000000000005357 115.0
WLSH2_k127_337845_18 transcriptional regulator - - - 0.00000000000000000000004626 106.0
WLSH2_k127_337845_19 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000001287 110.0
WLSH2_k127_337845_2 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 508.0
WLSH2_k127_337845_20 Tfp pilus assembly protein FimV - - - 0.00000002571 68.0
WLSH2_k127_337845_21 Protein of unknown function (DUF3106) - - - 0.0001163 51.0
WLSH2_k127_337845_4 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 361.0
WLSH2_k127_337845_5 Efflux ABC transporter permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 372.0
WLSH2_k127_337845_6 macrolide-specific efflux protein K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 322.0
WLSH2_k127_337845_7 Protein of unknown function (DUF3999) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 329.0
WLSH2_k127_337845_9 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 301.0
WLSH2_k127_3417008_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1361.0
WLSH2_k127_3417008_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000006282 160.0
WLSH2_k127_3417008_2 Outer membrane efflux protein - - - 0.000000000000002163 89.0
WLSH2_k127_3606303_0 Large extracellular alpha-helical protein K06894 - - 3.439e-253 857.0
WLSH2_k127_3606303_1 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 1.226e-195 623.0
WLSH2_k127_3606303_10 Domain of unknown function (DUF4301) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 327.0
WLSH2_k127_3606303_11 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000164 265.0
WLSH2_k127_3606303_12 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000002498 188.0
WLSH2_k127_3606303_13 Stage II sporulation D domain protein K06381 - - 0.00000000000000000000000000000000000000000001155 177.0
WLSH2_k127_3606303_14 PFAM Peptidase M23 K21471 - - 0.0000000000000000000000001159 122.0
WLSH2_k127_3606303_15 Ubiquinol-cytochrome C reductase - - - 0.00000000000000000000001127 106.0
WLSH2_k127_3606303_16 Protein of unknown function DUF86 - - - 0.00000000000000000000001513 106.0
WLSH2_k127_3606303_17 nucleotidyltransferase activity - - - 0.00000000000000000007686 94.0
WLSH2_k127_3606303_19 Septum formation initiator - - - 0.000838 46.0
WLSH2_k127_3606303_2 HI0933-like protein K10210 - 1.14.99.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 543.0
WLSH2_k127_3606303_20 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0009532 50.0
WLSH2_k127_3606303_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 530.0
WLSH2_k127_3606303_4 penicillin binding K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 507.0
WLSH2_k127_3606303_5 Belongs to the aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 463.0
WLSH2_k127_3606303_6 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 443.0
WLSH2_k127_3606303_7 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 419.0
WLSH2_k127_3606303_8 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 348.0
WLSH2_k127_3606303_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 341.0
WLSH2_k127_365812_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.184e-319 997.0
WLSH2_k127_365812_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008397 355.0
WLSH2_k127_365812_10 Protein of unknown function (DUF1571) - - - 0.000000000000000000000000000000000001016 147.0
WLSH2_k127_365812_11 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000267 126.0
WLSH2_k127_365812_12 PFAM Nitroreductase - - - 0.000000000000000000005222 101.0
WLSH2_k127_365812_13 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.000000000000000000009966 100.0
WLSH2_k127_365812_14 Phosphopantetheine attachment site - - - 0.0000000000000004381 88.0
WLSH2_k127_365812_15 Protein-S-isoprenylcysteine methyltransferase - - - 0.000000000000171 78.0
WLSH2_k127_365812_16 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000768 73.0
WLSH2_k127_365812_17 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372,K16363 - 3.5.1.108,4.2.1.59 0.0000003463 54.0
WLSH2_k127_365812_18 FabA-like domain K02372 - 4.2.1.59 0.00003816 53.0
WLSH2_k127_365812_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 330.0
WLSH2_k127_365812_3 Elongator protein 3, MiaB family, Radical SAM K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 313.0
WLSH2_k127_365812_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 301.0
WLSH2_k127_365812_5 Elongator protein 3, MiaB family, Radical SAM K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001222 289.0
WLSH2_k127_365812_6 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008162 286.0
WLSH2_k127_365812_7 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000003174 215.0
WLSH2_k127_365812_8 Enoyl-(Acyl carrier protein) reductase K00034,K03366 - 1.1.1.304,1.1.1.47,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000004969 211.0
WLSH2_k127_365812_9 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000001599 199.0
WLSH2_k127_3690807_0 Sulfatase - - - 0.00000005891 65.0
WLSH2_k127_37788_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 288.0
WLSH2_k127_37788_1 SPTR NmrA family protein - - - 0.00000000000000000000000000001677 128.0
WLSH2_k127_37788_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000001074 62.0
WLSH2_k127_37788_3 Transposase IS200 like - - - 0.000000003035 63.0
WLSH2_k127_3823809_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1585.0
WLSH2_k127_3823809_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1264.0
WLSH2_k127_3823809_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000001315 145.0
WLSH2_k127_3823809_11 - - - - 0.00000000000000000000000000000002152 129.0
WLSH2_k127_3823809_12 - - - - 0.0000000000000000000000000005418 118.0
WLSH2_k127_3823809_13 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000002442 119.0
WLSH2_k127_3823809_14 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000004163 103.0
WLSH2_k127_3823809_15 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000001155 92.0
WLSH2_k127_3823809_16 - - - - 0.000000000000000005056 85.0
WLSH2_k127_3823809_17 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000002433 85.0
WLSH2_k127_3823809_19 - - - - 0.00000000000003711 76.0
WLSH2_k127_3823809_2 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 366.0
WLSH2_k127_3823809_20 COG NOG15344 non supervised orthologous group - - - 0.0000000000008078 72.0
WLSH2_k127_3823809_21 ORF located using Blastx - - - 0.00000000000324 71.0
WLSH2_k127_3823809_22 - - - - 0.00000000001411 68.0
WLSH2_k127_3823809_24 COG NOG14552 non supervised orthologous group - - - 0.0000000001244 62.0
WLSH2_k127_3823809_25 COG NOG14600 non supervised orthologous group - - - 0.0000000001828 65.0
WLSH2_k127_3823809_27 - - - - 0.00000006636 55.0
WLSH2_k127_3823809_28 non supervised orthologous group - - - 0.0000001354 54.0
WLSH2_k127_3823809_29 - - - - 0.0000004342 53.0
WLSH2_k127_3823809_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004163 251.0
WLSH2_k127_3823809_30 non supervised orthologous group - - - 0.000002218 51.0
WLSH2_k127_3823809_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002794 210.0
WLSH2_k127_3823809_5 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000004433 207.0
WLSH2_k127_3823809_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000002988 216.0
WLSH2_k127_3823809_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000007298 186.0
WLSH2_k127_3823809_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000003933 179.0
WLSH2_k127_3823809_9 - - - - 0.00000000000000000000000000000000000000000003084 163.0
WLSH2_k127_3825200_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1543.0
WLSH2_k127_3825200_1 HsdM N-terminal domain K03427 - 2.1.1.72 1.753e-287 888.0
WLSH2_k127_3825200_10 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000003441 158.0
WLSH2_k127_3825200_11 SEC-C Motif Domain Protein - - - 0.00000000000000000000000000000003568 138.0
WLSH2_k127_3825200_12 Homeodomain-like domain - - - 0.00000000000003941 74.0
WLSH2_k127_3825200_2 PFAM filamentation induced by cAMP protein Fic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 458.0
WLSH2_k127_3825200_3 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 380.0
WLSH2_k127_3825200_4 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 366.0
WLSH2_k127_3825200_5 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 360.0
WLSH2_k127_3825200_6 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006788 256.0
WLSH2_k127_3825200_7 - - - - 0.00000000000000000000000000000000000000000000000000000001144 206.0
WLSH2_k127_3825200_8 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000003701 157.0
WLSH2_k127_3825200_9 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000003346 154.0
WLSH2_k127_3827582_0 Belongs to the ClpA ClpB family K03696 - - 1.884e-315 986.0
WLSH2_k127_3827582_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 7.712e-232 745.0
WLSH2_k127_3827582_10 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000001649 235.0
WLSH2_k127_3827582_11 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000008498 99.0
WLSH2_k127_3827582_12 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.00000000000000000182 91.0
WLSH2_k127_3827582_13 - - - - 0.000000004388 64.0
WLSH2_k127_3827582_14 Modulates RecA activity K03565 GO:0006282,GO:0008150,GO:0019219,GO:0019222,GO:0031323,GO:0048583,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0080090,GO:0080134,GO:0080135,GO:2001020 - 0.0000958 51.0
WLSH2_k127_3827582_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 617.0
WLSH2_k127_3827582_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 557.0
WLSH2_k127_3827582_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 544.0
WLSH2_k127_3827582_5 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 442.0
WLSH2_k127_3827582_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 391.0
WLSH2_k127_3827582_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 375.0
WLSH2_k127_3827582_8 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002882 291.0
WLSH2_k127_3827582_9 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000005157 234.0
WLSH2_k127_3834871_0 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 381.0
WLSH2_k127_3834871_1 ORF6N domain - - - 0.0000000000000000000000000000000000000000006835 165.0
WLSH2_k127_3834871_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000001005 155.0
WLSH2_k127_3834871_3 - - - - 0.0000000000000000001787 92.0
WLSH2_k127_3834871_4 HEAT repeats - - - 0.000001334 61.0
WLSH2_k127_3834871_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000003496 57.0
WLSH2_k127_3857161_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000005637 248.0
WLSH2_k127_3862391_0 Site-specific recombinase, DNA invertase Pin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001579 262.0
WLSH2_k127_3862391_1 Domain of unknown function (DUF4870) - - - 0.0000006807 54.0
WLSH2_k127_3878752_0 Transposase domain (DUF772) - - - 0.00000000000000000000000000000000000000000000000000003518 207.0
WLSH2_k127_3878752_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000005644 161.0
WLSH2_k127_4001977_0 - - - - 0.0001744 49.0
WLSH2_k127_4001977_1 Recombinase zinc beta ribbon domain - - - 0.0008754 49.0
WLSH2_k127_4001977_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0009895 53.0
WLSH2_k127_4015289_0 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 350.0
WLSH2_k127_4015289_1 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 308.0
WLSH2_k127_4015289_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 299.0
WLSH2_k127_4015289_3 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.000000000000000000000000000000000621 139.0
WLSH2_k127_4015289_4 Cold shock protein domain K03704 - - 0.0000000000000000000000002071 108.0
WLSH2_k127_4015289_5 modulation protein K05808 - - 0.00000000000000006696 85.0
WLSH2_k127_4015289_6 Lipopolysaccharide-assembly, LptC-related - - - 0.0000001463 60.0
WLSH2_k127_4063054_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000002139 137.0
WLSH2_k127_4063054_1 - - - - 0.0000000000002708 79.0
WLSH2_k127_409375_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 489.0
WLSH2_k127_409375_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 431.0
WLSH2_k127_409375_10 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007769 277.0
WLSH2_k127_409375_11 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000009426 274.0
WLSH2_k127_409375_12 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000001043 222.0
WLSH2_k127_409375_13 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000009321 214.0
WLSH2_k127_409375_14 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000004408 212.0
WLSH2_k127_409375_15 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000007817 220.0
WLSH2_k127_409375_16 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000002106 205.0
WLSH2_k127_409375_17 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000004802 196.0
WLSH2_k127_409375_18 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000001709 186.0
WLSH2_k127_409375_19 heptosyltransferase II K02843 - - 0.0000000000000000000000000000000000000000000006078 178.0
WLSH2_k127_409375_2 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 361.0
WLSH2_k127_409375_20 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000004546 160.0
WLSH2_k127_409375_21 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000002556 171.0
WLSH2_k127_409375_22 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000007251 139.0
WLSH2_k127_409375_23 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000004121 137.0
WLSH2_k127_409375_24 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000001416 107.0
WLSH2_k127_409375_25 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000004557 111.0
WLSH2_k127_409375_26 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000003112 91.0
WLSH2_k127_409375_27 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000002558 90.0
WLSH2_k127_409375_28 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000000000005787 73.0
WLSH2_k127_409375_29 Pilus assembly protein, PilO K02664 - - 0.000000000003812 74.0
WLSH2_k127_409375_3 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 356.0
WLSH2_k127_409375_30 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000002409 63.0
WLSH2_k127_409375_31 COG3307 Lipid A core - O-antigen ligase and related enzymes K18814 - - 0.00000001536 68.0
WLSH2_k127_409375_32 Transmembrane and TPR repeat-containing protein - - - 0.0000005911 59.0
WLSH2_k127_409375_33 O-Antigen ligase - - - 0.000005188 60.0
WLSH2_k127_409375_34 OmpA family K03286 - - 0.00005778 55.0
WLSH2_k127_409375_35 PFAM Fimbrial assembly family protein K02663 - - 0.0007487 49.0
WLSH2_k127_409375_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 354.0
WLSH2_k127_409375_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 340.0
WLSH2_k127_409375_6 involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 336.0
WLSH2_k127_409375_7 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 293.0
WLSH2_k127_409375_8 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001085 275.0
WLSH2_k127_409375_9 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000003339 276.0
WLSH2_k127_4104900_0 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000393 211.0
WLSH2_k127_4104900_1 long-chain fatty acid transporting porin activity - - - 0.00000000000000001523 95.0
WLSH2_k127_4104900_2 cellulose binding - - - 0.000007626 57.0
WLSH2_k127_4104900_3 ompA family - - - 0.00002502 56.0
WLSH2_k127_4128276_0 Protein of unknown function, DUF255 K06888 - - 1.217e-195 633.0
WLSH2_k127_4128276_1 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003038 293.0
WLSH2_k127_4128276_2 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001753 270.0
WLSH2_k127_4128276_3 ORF6N domain - - - 0.000000000000000000000000000000000000000006927 160.0
WLSH2_k127_4128276_4 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000005578 129.0
WLSH2_k127_4128276_5 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000001106 106.0
WLSH2_k127_4128674_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 299.0
WLSH2_k127_4128674_1 proteolysis - - - 0.000000000000000000000000000000000002425 147.0
WLSH2_k127_4128674_2 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000001221 87.0
WLSH2_k127_4128674_3 PFAM Diacylglycerol kinase, catalytic - - - 0.000000000003661 77.0
WLSH2_k127_4128674_4 Type IV Pilus-assembly protein W K02672 - - 0.0008459 49.0
WLSH2_k127_4181017_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 6.13e-199 663.0
WLSH2_k127_4181017_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 611.0
WLSH2_k127_4181017_10 Creatinase/Prolidase N-terminal domain K01262,K01271 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000002892 219.0
WLSH2_k127_4181017_11 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000001161 205.0
WLSH2_k127_4181017_12 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000008455 207.0
WLSH2_k127_4181017_13 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000003038 198.0
WLSH2_k127_4181017_14 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000003419 210.0
WLSH2_k127_4181017_15 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000002147 207.0
WLSH2_k127_4181017_16 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000005983 195.0
WLSH2_k127_4181017_17 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000003848 187.0
WLSH2_k127_4181017_18 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.000000000000000000000000000000000000000000001783 176.0
WLSH2_k127_4181017_19 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000004678 171.0
WLSH2_k127_4181017_2 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 532.0
WLSH2_k127_4181017_20 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000006119 167.0
WLSH2_k127_4181017_21 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000005851 159.0
WLSH2_k127_4181017_22 Tetratricopeptide repeat - - - 0.0000000000000000000000000000007334 140.0
WLSH2_k127_4181017_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000004905 133.0
WLSH2_k127_4181017_24 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000001145 96.0
WLSH2_k127_4181017_25 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.000000000000000001665 91.0
WLSH2_k127_4181017_26 outer membrane efflux protein - - - 0.000000000001543 81.0
WLSH2_k127_4181017_27 Fibronectin type III domain - - - 0.00000003264 69.0
WLSH2_k127_4181017_28 Hep Hag repeat protein - - - 0.0000000419 63.0
WLSH2_k127_4181017_29 - - - - 0.00000008472 55.0
WLSH2_k127_4181017_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 503.0
WLSH2_k127_4181017_30 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000002322 60.0
WLSH2_k127_4181017_31 Molybdopterin K03636 - - 0.00001083 51.0
WLSH2_k127_4181017_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 426.0
WLSH2_k127_4181017_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 373.0
WLSH2_k127_4181017_6 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 365.0
WLSH2_k127_4181017_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 297.0
WLSH2_k127_4181017_8 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001363 267.0
WLSH2_k127_4181017_9 Integral membrane sensor signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001347 233.0
WLSH2_k127_4229105_0 Sulfatase - - - 0.00003839 56.0
WLSH2_k127_4290446_0 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 485.0
WLSH2_k127_4290446_1 uridine kinase K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 438.0
WLSH2_k127_4290446_10 - - - - 0.0000000000000008728 84.0
WLSH2_k127_4290446_11 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.0000000000000188 87.0
WLSH2_k127_4290446_12 ATP-dependent Clp protease adaptor protein ClpS - - - 0.000000002118 62.0
WLSH2_k127_4290446_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 396.0
WLSH2_k127_4290446_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000005204 234.0
WLSH2_k127_4290446_4 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000002531 229.0
WLSH2_k127_4290446_5 E3 Ubiquitin ligase - - - 0.00000000000000000000000000000000000000000000000000231 195.0
WLSH2_k127_4290446_7 ROK family K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.00000000000000000000000000000000000000006388 160.0
WLSH2_k127_4290446_8 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000006011 110.0
WLSH2_k127_4290446_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000001947 88.0
WLSH2_k127_4296933_0 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 392.0
WLSH2_k127_4296933_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000005733 245.0
WLSH2_k127_4296933_10 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000007872 89.0
WLSH2_k127_4296933_11 domain protein K13735,K15125,K20276 - - 0.0000000002133 76.0
WLSH2_k127_4296933_12 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000005755 66.0
WLSH2_k127_4296933_13 Belongs to the UPF0109 family K06960 - - 0.00000002966 57.0
WLSH2_k127_4296933_14 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000003851 60.0
WLSH2_k127_4296933_15 Parallel beta-helix repeats - - - 0.00003754 59.0
WLSH2_k127_4296933_16 TonB C terminal K03832 - - 0.0000694 55.0
WLSH2_k127_4296933_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000002337 235.0
WLSH2_k127_4296933_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000007434 207.0
WLSH2_k127_4296933_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000001221 166.0
WLSH2_k127_4296933_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000002233 154.0
WLSH2_k127_4296933_6 PFAM Tetratricopeptide - - - 0.000000000000000000000000000000845 142.0
WLSH2_k127_4296933_7 Tetratricopeptide repeat - - - 0.000000000000000000000000005323 125.0
WLSH2_k127_4296933_8 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000003142 99.0
WLSH2_k127_4296933_9 Belongs to the UPF0102 family K07460 - - 0.0000000000000000002444 94.0
WLSH2_k127_4310538_0 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000001255 172.0
WLSH2_k127_4310538_1 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000002084 159.0
WLSH2_k127_4310538_2 Maf-like protein K06287 - - 0.00000000000000000000000000000001506 135.0
WLSH2_k127_4310538_3 protein involved in tolerance to K03926 - - 0.0000000000000000000000001346 111.0
WLSH2_k127_4310538_4 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000007406 100.0
WLSH2_k127_4310538_5 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000000000000006481 90.0
WLSH2_k127_4310538_6 Sigma-54 factor, core binding domain K03092 - - 0.0001981 53.0
WLSH2_k127_4367620_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 417.0
WLSH2_k127_4367620_1 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 386.0
WLSH2_k127_4367620_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 381.0
WLSH2_k127_4367620_3 peroxidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001432 283.0
WLSH2_k127_443719_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688,K21298 - 2.4.1.20,2.4.1.333 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 644.0
WLSH2_k127_443719_1 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 513.0
WLSH2_k127_443719_10 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000008008 68.0
WLSH2_k127_443719_11 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000166 52.0
WLSH2_k127_443719_12 Tellurite resistance protein TehB - - - 0.0003338 46.0
WLSH2_k127_443719_2 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 471.0
WLSH2_k127_443719_3 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003442 250.0
WLSH2_k127_443719_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000003058 237.0
WLSH2_k127_443719_5 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000004022 213.0
WLSH2_k127_443719_6 PFAM tRNA rRNA methyltransferase, SpoU K02533 - - 0.0000000000000000000000000000000000000000006048 172.0
WLSH2_k127_443719_7 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000005485 115.0
WLSH2_k127_443719_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000002907 95.0
WLSH2_k127_443719_9 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000002305 87.0
WLSH2_k127_4438056_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 424.0
WLSH2_k127_4438056_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004799 286.0
WLSH2_k127_4438056_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000009272 279.0
WLSH2_k127_4438056_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000001306 176.0
WLSH2_k127_4438056_4 MazG family K02499 - - 0.000000000000000000000000000000000000003653 150.0
WLSH2_k127_4438056_5 Cytochrome C assembly protein - - - 0.0000000000000000000000000000002197 134.0
WLSH2_k127_4438056_6 PIN domain - - - 0.0000000000000000000000003884 114.0
WLSH2_k127_4438056_7 Protein of unknown function (DUF2442) - - - 0.000000000000000000000005857 104.0
WLSH2_k127_4438056_8 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.000000000000000003072 93.0
WLSH2_k127_4438056_9 COG1587 Uroporphyrinogen-III synthase K01719 GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.75 0.0008695 50.0
WLSH2_k127_4587132_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 585.0
WLSH2_k127_4587132_1 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 524.0
WLSH2_k127_4587132_10 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000001516 111.0
WLSH2_k127_4587132_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000216 91.0
WLSH2_k127_4587132_12 RibD C-terminal domain - - - 0.00000000000002762 75.0
WLSH2_k127_4587132_2 PFAM HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 468.0
WLSH2_k127_4587132_3 Beta-Casp domain K07576,K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 366.0
WLSH2_k127_4587132_4 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 353.0
WLSH2_k127_4587132_5 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000008415 262.0
WLSH2_k127_4587132_6 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000001089 222.0
WLSH2_k127_4587132_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000000000000000000000000000000000000000000000168 216.0
WLSH2_k127_4587132_8 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000003121 158.0
WLSH2_k127_4587132_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000002125 155.0
WLSH2_k127_4646596_0 Glycogen debranching enzyme - - - 2.365e-195 614.0
WLSH2_k127_4646596_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000002952 131.0
WLSH2_k127_4648472_0 ABC transporter, ATP-binding protein K13926 - - 0.0 1149.0
WLSH2_k127_4648472_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1141.0
WLSH2_k127_4648472_10 Autotransporter beta-domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 381.0
WLSH2_k127_4648472_11 ATPase (AAA superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 349.0
WLSH2_k127_4648472_12 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 336.0
WLSH2_k127_4648472_13 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 335.0
WLSH2_k127_4648472_14 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006078 286.0
WLSH2_k127_4648472_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002393 255.0
WLSH2_k127_4648472_16 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000002074 173.0
WLSH2_k127_4648472_17 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000001446 172.0
WLSH2_k127_4648472_18 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000006853 164.0
WLSH2_k127_4648472_19 Protein of unknown function (DUF2442) - - - 0.000000000000000000004939 96.0
WLSH2_k127_4648472_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 563.0
WLSH2_k127_4648472_20 COG2829 Outer membrane phospholipase A K01058 - 3.1.1.32,3.1.1.4 0.0000000000000008801 87.0
WLSH2_k127_4648472_21 - - - - 0.0000000000001885 78.0
WLSH2_k127_4648472_22 - - - - 0.000000000007867 77.0
WLSH2_k127_4648472_23 SMART Chromosomal replication initiator DnaA domain - - - 0.00000001718 57.0
WLSH2_k127_4648472_24 polygalacturonase activity - - - 0.00001194 56.0
WLSH2_k127_4648472_3 Phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 549.0
WLSH2_k127_4648472_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 554.0
WLSH2_k127_4648472_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 486.0
WLSH2_k127_4648472_6 ATPase (AAA superfamily) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 479.0
WLSH2_k127_4648472_7 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 452.0
WLSH2_k127_4648472_8 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 455.0
WLSH2_k127_4648472_9 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 446.0
WLSH2_k127_4648618_0 Phospholipase D. Active site motifs. - - - 0.0000000912 64.0
WLSH2_k127_4649336_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.676e-228 718.0
WLSH2_k127_4649336_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008884 525.0
WLSH2_k127_4649336_2 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 440.0
WLSH2_k127_4649336_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000002264 162.0
WLSH2_k127_4649336_4 PFAM outer membrane efflux protein - - - 0.0000007264 58.0
WLSH2_k127_4649336_5 Protein tyrosine kinase - - - 0.00001157 60.0
WLSH2_k127_4649336_6 Protein tyrosine kinase - - - 0.00001157 60.0
WLSH2_k127_4649604_0 HsdM N-terminal domain K03427 - 2.1.1.72 0.0 1159.0
WLSH2_k127_4649604_1 type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000000000000000000000001392 165.0
WLSH2_k127_4649604_2 - - - - 0.000000000000000000000000000000000000000004176 162.0
WLSH2_k127_4649604_3 TIGRFAM Competence protein ComEA, helix-hairpin-helix - - - 0.000006504 59.0
WLSH2_k127_4652295_0 Nucleotidyltransferase - - - 0.00000000000000003031 85.0
WLSH2_k127_4652295_1 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.0000003214 63.0
WLSH2_k127_4652295_2 - - - - 0.0004335 47.0
WLSH2_k127_4652618_0 PFAM C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 407.0
WLSH2_k127_4652618_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 318.0
WLSH2_k127_4652618_2 May nick specific sequences that contain T G mispairs resulting from m5C-deamination - - - 0.0000000000000000000000000000000001716 138.0
WLSH2_k127_4652618_3 Nucleotidyltransferase - - - 0.00000000000000002681 88.0
WLSH2_k127_4652618_4 COG3209 Rhs family protein - - - 0.0000000000000006455 87.0
WLSH2_k127_4652618_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000003005 54.0
WLSH2_k127_4652618_6 - - - - 0.0001506 51.0
WLSH2_k127_4652618_7 - - - - 0.0005938 46.0
WLSH2_k127_477556_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.611e-219 689.0
WLSH2_k127_477556_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.763e-197 627.0
WLSH2_k127_477556_10 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000005815 203.0
WLSH2_k127_477556_11 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000002111 199.0
WLSH2_k127_477556_12 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000001727 169.0
WLSH2_k127_477556_13 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000002585 126.0
WLSH2_k127_477556_14 - - - - 0.000000000000000000372 100.0
WLSH2_k127_477556_15 - - - - 0.000000000000000001112 99.0
WLSH2_k127_477556_16 - - - - 0.00000000000000004546 94.0
WLSH2_k127_477556_17 cell adhesion K02650,K02682 - - 0.000000003693 64.0
WLSH2_k127_477556_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 614.0
WLSH2_k127_477556_3 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 604.0
WLSH2_k127_477556_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 562.0
WLSH2_k127_477556_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 465.0
WLSH2_k127_477556_6 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 417.0
WLSH2_k127_477556_7 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003845 248.0
WLSH2_k127_477556_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000004827 233.0
WLSH2_k127_4844842_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 464.0
WLSH2_k127_4844842_1 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 391.0
WLSH2_k127_4844842_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008386 282.0
WLSH2_k127_4844842_3 Esterase PHB depolymerase - - - 0.00000000000000000000317 111.0
WLSH2_k127_5000383_0 Aminotransferase class I and II K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 387.0
WLSH2_k127_5000383_1 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.0001342 53.0
WLSH2_k127_5001690_0 Biotin and Thiamin Synthesis associated K03150 - 4.1.99.19 1.772e-210 664.0
WLSH2_k127_5001690_1 PFAM fumarate lyase K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 541.0
WLSH2_k127_5001690_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000009677 266.0
WLSH2_k127_5001690_11 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000001932 212.0
WLSH2_k127_5001690_12 PFAM Cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000003624 170.0
WLSH2_k127_5001690_13 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000006743 168.0
WLSH2_k127_5001690_14 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000008565 163.0
WLSH2_k127_5001690_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000001039 125.0
WLSH2_k127_5001690_16 Iron-only hydrogenase system regulator - - - 0.00000000000000000000000002416 109.0
WLSH2_k127_5001690_17 Protein of unknown function (DUF3015) - - - 0.00000000000000000000003039 105.0
WLSH2_k127_5001690_18 Protein of unknown function (DUF3015) - - - 0.000000000000000000009633 98.0
WLSH2_k127_5001690_19 Heavy-metal resistance - - - 0.00001739 54.0
WLSH2_k127_5001690_2 50S ribosome-binding GTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 516.0
WLSH2_k127_5001690_20 Domain of unknown function (DUF4179) - - - 0.000619 50.0
WLSH2_k127_5001690_3 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 377.0
WLSH2_k127_5001690_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 357.0
WLSH2_k127_5001690_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 346.0
WLSH2_k127_5001690_6 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 348.0
WLSH2_k127_5001690_7 PFAM Radical SAM K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 328.0
WLSH2_k127_5001690_8 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 311.0
WLSH2_k127_5001690_9 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 303.0
WLSH2_k127_5001936_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 526.0
WLSH2_k127_5001936_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 337.0
WLSH2_k127_5001936_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000002934 231.0
WLSH2_k127_5001936_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000002179 192.0
WLSH2_k127_5001936_4 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000004508 197.0
WLSH2_k127_5002006_0 Methicillin resistance protein K05363,K11693 - 2.3.2.10,2.3.2.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 321.0
WLSH2_k127_5002006_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000006915 55.0
WLSH2_k127_5149662_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 328.0
WLSH2_k127_5149662_1 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000001229 232.0
WLSH2_k127_5149662_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000009605 221.0
WLSH2_k127_5149662_3 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000005702 222.0
WLSH2_k127_5149662_4 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.000000000000000009966 98.0
WLSH2_k127_5149662_5 RHS repeat-associated core domain protein - - - 0.00000000000000214 91.0
WLSH2_k127_5149662_6 Amidohydrolase K07045 - - 0.000000000004237 77.0
WLSH2_k127_5149861_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000001078 224.0
WLSH2_k127_5158557_0 PFAM metallophosphoesterase K07098 - - 0.000000000000000000001001 110.0
WLSH2_k127_5301843_0 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000000000000000000000000000000000000000000000000000003977 253.0
WLSH2_k127_5301843_1 Alpha-L-fucosidase - - - 0.000000000000000000000000005776 129.0
WLSH2_k127_5301843_2 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000001759 108.0
WLSH2_k127_5301843_4 Bacterial Ig-like domain (group 3) - - - 0.000000000000003416 91.0
WLSH2_k127_5301843_5 Esterase PHB depolymerase - - - 0.00000000000003021 87.0
WLSH2_k127_5302010_0 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000000000059 153.0
WLSH2_k127_5302010_1 Alpha-L-fucosidase - - - 0.00000000000000000000000002824 127.0
WLSH2_k127_5302010_2 Alpha-L-fucosidase - - - 0.0000000000000000000004425 113.0
WLSH2_k127_5302010_3 RHS Repeat - - - 0.000000000000000001736 102.0
WLSH2_k127_5377866_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 374.0
WLSH2_k127_5377866_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000002837 231.0
WLSH2_k127_5405602_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 396.0
WLSH2_k127_5405602_1 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 361.0
WLSH2_k127_5405602_10 YacP-like NYN domain K06962 - - 0.00000000004744 70.0
WLSH2_k127_5405602_11 Fungal specific transcription factor domain - - - 0.00001161 56.0
WLSH2_k127_5405602_12 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0003248 47.0
WLSH2_k127_5405602_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 324.0
WLSH2_k127_5405602_3 Protein of unknown function (DUF3800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 302.0
WLSH2_k127_5405602_4 Sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002954 262.0
WLSH2_k127_5405602_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000155 227.0
WLSH2_k127_5405602_6 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000002141 187.0
WLSH2_k127_5405602_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000403 145.0
WLSH2_k127_5405602_8 - - - - 0.0000000000000000000000007029 113.0
WLSH2_k127_5405602_9 by glimmer - - - 0.000000000000000007418 89.0
WLSH2_k127_5406074_0 B12 binding domain K00548 - 2.1.1.13 0.0 1306.0
WLSH2_k127_5406074_1 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1107.0
WLSH2_k127_5406074_10 - - - - 0.0000000000000000000000000000000000000000000000000000001304 222.0
WLSH2_k127_5406074_11 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000000000000000000000000000009816 194.0
WLSH2_k127_5406074_12 RNA polymerase sigma factor K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000003425 185.0
WLSH2_k127_5406074_13 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000762 140.0
WLSH2_k127_5406074_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000009068 132.0
WLSH2_k127_5406074_15 - - - - 0.00000000000000000000001378 118.0
WLSH2_k127_5406074_16 Arsenate reductase and related K00537 - 1.20.4.1 0.00000000000000000001361 96.0
WLSH2_k127_5406074_17 membrane-associated protein - - - 0.00000000000000005524 90.0
WLSH2_k127_5406074_18 COGs COG0058 Glucan phosphorylase K00688,K00691 - 2.4.1.1,2.4.1.8 0.000000000000006397 88.0
WLSH2_k127_5406074_19 Bacterial membrane protein, YfhO - - - 0.000000000007381 79.0
WLSH2_k127_5406074_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 561.0
WLSH2_k127_5406074_20 Putative zinc-finger - - - 0.0000000009616 64.0
WLSH2_k127_5406074_3 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 485.0
WLSH2_k127_5406074_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 420.0
WLSH2_k127_5406074_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 401.0
WLSH2_k127_5406074_6 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 306.0
WLSH2_k127_5406074_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 315.0
WLSH2_k127_5406074_8 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006932 271.0
WLSH2_k127_5406074_9 FAD dependent oxidoreductase K00285,K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000001598 253.0
WLSH2_k127_554927_0 Terminase RNaseH-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 347.0
WLSH2_k127_554927_1 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 352.0
WLSH2_k127_554927_10 - - - - 0.00000003499 62.0
WLSH2_k127_554927_12 phage tail tape measure protein - - - 0.000009385 59.0
WLSH2_k127_554927_13 - - - - 0.00003359 51.0
WLSH2_k127_554927_2 Phage portal protein - - - 0.00000000000000000000000000000000000000000000000000000006478 220.0
WLSH2_k127_554927_3 crossover junction endodeoxyribonuclease activity - - - 0.00000000000000000000000000000000000000000000001498 184.0
WLSH2_k127_554927_4 Replication initiation and membrane attachment - - - 0.000000000000000000000003968 113.0
WLSH2_k127_554927_5 Phage prohead protease, HK97 family - - - 0.0000000000000000000002094 104.0
WLSH2_k127_554927_6 Protein of unknown function (DUF2793) - - - 0.000000000000000000005433 98.0
WLSH2_k127_554927_7 phage major capsid protein, HK97 family - - - 0.00000000000000002094 95.0
WLSH2_k127_554927_8 - - - - 0.00000000003584 70.0
WLSH2_k127_554927_9 defense response to virus - - - 0.00000003065 65.0
WLSH2_k127_5561880_0 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 296.0
WLSH2_k127_5561880_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000006071 94.0
WLSH2_k127_5561880_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000002078 80.0
WLSH2_k127_5561880_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000004042 83.0
WLSH2_k127_5561880_4 Histidine kinase - - - 0.000003026 57.0
WLSH2_k127_5584683_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 343.0
WLSH2_k127_5584683_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 293.0
WLSH2_k127_5584683_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000001357 228.0
WLSH2_k127_5584683_3 PFAM Imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000001173 209.0
WLSH2_k127_5584683_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000002604 198.0
WLSH2_k127_5584683_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000007585 158.0
WLSH2_k127_5584683_6 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000001062 120.0
WLSH2_k127_5584683_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.000000000009081 72.0
WLSH2_k127_5611639_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.736e-230 719.0
WLSH2_k127_5611639_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 497.0
WLSH2_k127_5611639_2 TIGRFAM methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000006038 222.0
WLSH2_k127_5670858_0 SPTR CHU large protein - - - 0.0006735 52.0
WLSH2_k127_5754939_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.955e-195 639.0
WLSH2_k127_5754939_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 327.0
WLSH2_k127_5754939_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 307.0
WLSH2_k127_5754939_3 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000174 275.0
WLSH2_k127_5754939_4 Catabolite gene activator and regulatory subunit of cAMP-dependent protein K10914 - - 0.00000000001153 73.0
WLSH2_k127_5787893_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 317.0
WLSH2_k127_5787893_1 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007518 280.0
WLSH2_k127_5787893_2 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000319 159.0
WLSH2_k127_5787893_3 Acetyltransferase (GNAT) domain - - - 0.000000002898 65.0
WLSH2_k127_5837670_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 324.0
WLSH2_k127_5837670_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000124 216.0
WLSH2_k127_5837670_2 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000007102 153.0
WLSH2_k127_5837670_3 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000001051 158.0
WLSH2_k127_5837670_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000001231 95.0
WLSH2_k127_5837670_5 photosystem II stabilization K02237 - - 0.000000005512 67.0
WLSH2_k127_5837670_6 Psort location OuterMembrane, score - - - 0.00000001451 68.0
WLSH2_k127_5837670_7 Lamin Tail Domain - - - 0.000001406 60.0
WLSH2_k127_5837670_8 pilus organization - - - 0.0001262 54.0
WLSH2_k127_5848535_0 ABC transporter - - - 2.957e-210 667.0
WLSH2_k127_5848535_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 556.0
WLSH2_k127_5848535_10 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000001027 217.0
WLSH2_k127_5848535_11 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.00000000000000000000000000000000000000000000000000007007 193.0
WLSH2_k127_5848535_12 Belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K03977 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25 0.0000000000000000000000000000000000000000000000000005491 192.0
WLSH2_k127_5848535_13 Telomere recombination K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000006496 157.0
WLSH2_k127_5848535_14 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000001917 156.0
WLSH2_k127_5848535_15 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 0.000000000000000000000006795 118.0
WLSH2_k127_5848535_16 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000002744 89.0
WLSH2_k127_5848535_17 Probable zinc-ribbon domain - - - 0.000000001858 61.0
WLSH2_k127_5848535_2 ABC transporter K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 449.0
WLSH2_k127_5848535_3 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 412.0
WLSH2_k127_5848535_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009287 404.0
WLSH2_k127_5848535_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 364.0
WLSH2_k127_5848535_6 - K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 324.0
WLSH2_k127_5848535_7 ArgJ family K00620,K00930 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 324.0
WLSH2_k127_5848535_8 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000001191 233.0
WLSH2_k127_5848535_9 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000001772 231.0
WLSH2_k127_5904498_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 - 2.4.1.321 0.00000000000000000000000000000000001715 158.0
WLSH2_k127_5904498_1 photosystem II stabilization K02237 - - 0.0000000264 65.0
WLSH2_k127_5985985_0 alpha amylase catalytic K01182,K05343 - 3.2.1.1,3.2.1.10,5.4.99.16 0.0 1236.0
WLSH2_k127_5985985_1 Glycosyltransferase family 20 - - - 6.628e-238 755.0
WLSH2_k127_5985985_2 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 358.0
WLSH2_k127_5985985_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000002044 250.0
WLSH2_k127_5985985_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000003821 150.0
WLSH2_k127_5985985_5 OmpA family K02557 - - 0.0000000000000000000000000000000001324 144.0
WLSH2_k127_5985985_6 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000001542 139.0
WLSH2_k127_5985985_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000004905 133.0
WLSH2_k127_5985985_8 Could be involved in septation K06412 - - 0.000000000000000000000002283 105.0
WLSH2_k127_5985985_9 - - - - 0.0001562 45.0
WLSH2_k127_598851_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 9.672e-240 747.0
WLSH2_k127_598851_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 431.0
WLSH2_k127_598851_2 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 345.0
WLSH2_k127_598851_3 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 332.0
WLSH2_k127_598851_4 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 321.0
WLSH2_k127_598851_5 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 300.0
WLSH2_k127_598851_6 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008119 265.0
WLSH2_k127_598851_7 subunit of a heme lyase K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.0000000000000000000001023 109.0
WLSH2_k127_598851_8 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000008691 83.0
WLSH2_k127_599056_0 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 385.0
WLSH2_k127_599056_1 Belongs to the SEDS family. MrdB RodA subfamily K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000004142 260.0
WLSH2_k127_599056_2 penicillin binding K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000001901 225.0
WLSH2_k127_5991352_0 Elongation factor G C-terminus K06207 - - 1.682e-211 676.0
WLSH2_k127_5991352_1 Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) K00209 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.44,1.3.1.9 0.000004037 52.0
WLSH2_k127_6033110_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 469.0
WLSH2_k127_6033110_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000001138 141.0
WLSH2_k127_6158995_0 glutamate synthase K00284 - 1.4.7.1 0.0 2175.0
WLSH2_k127_6158995_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K04090 - 1.2.7.8 0.0 1045.0
WLSH2_k127_6158995_10 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 316.0
WLSH2_k127_6158995_11 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 316.0
WLSH2_k127_6158995_12 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 299.0
WLSH2_k127_6158995_13 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001075 260.0
WLSH2_k127_6158995_14 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000003075 255.0
WLSH2_k127_6158995_15 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000884 173.0
WLSH2_k127_6158995_16 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000001635 165.0
WLSH2_k127_6158995_17 Oxidoreductase FAD NAD(P)-binding domain protein K00351 - 1.6.5.8 0.0000000000000000000000000000000000000002179 159.0
WLSH2_k127_6158995_18 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000001122 150.0
WLSH2_k127_6158995_19 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000005176 132.0
WLSH2_k127_6158995_2 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 5.119e-244 764.0
WLSH2_k127_6158995_20 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000001023 139.0
WLSH2_k127_6158995_21 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000001119 142.0
WLSH2_k127_6158995_22 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000002663 141.0
WLSH2_k127_6158995_23 Transporter associated domain - - - 0.0000000000000000000000000004758 126.0
WLSH2_k127_6158995_24 Stress responsive A/B Barrel Domain - - - 0.00000000000000000000000003571 110.0
WLSH2_k127_6158995_25 Diguanylate cyclase - - - 0.0000000000000000000000001506 120.0
WLSH2_k127_6158995_26 diguanylate cyclase - - - 0.0000000000000000000000064 115.0
WLSH2_k127_6158995_27 DNA protecting protein DprA K04096 - - 0.00000000000001619 80.0
WLSH2_k127_6158995_28 LysM domain - - - 0.000000000001288 79.0
WLSH2_k127_6158995_29 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000007052 70.0
WLSH2_k127_6158995_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.394e-208 672.0
WLSH2_k127_6158995_30 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000005659 65.0
WLSH2_k127_6158995_31 PD-(D/E)XK nuclease superfamily K07465 - - 0.0000000101 67.0
WLSH2_k127_6158995_32 Dolichyl-phosphate-mannose-protein mannosyltransferase K00786 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000004433 66.0
WLSH2_k127_6158995_33 DNA-binding transcriptional activator of the SARP family - - - 0.00001247 58.0
WLSH2_k127_6158995_4 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 493.0
WLSH2_k127_6158995_5 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 437.0
WLSH2_k127_6158995_6 Zinc-binding dehydrogenase K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 431.0
WLSH2_k127_6158995_7 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 389.0
WLSH2_k127_6158995_8 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 369.0
WLSH2_k127_6158995_9 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 344.0
WLSH2_k127_6213006_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.736e-257 822.0
WLSH2_k127_6213006_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 324.0
WLSH2_k127_6213006_2 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002249 276.0
WLSH2_k127_6213006_3 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000005181 213.0
WLSH2_k127_6213006_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000001657 212.0
WLSH2_k127_6213006_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000001518 220.0
WLSH2_k127_6213006_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000003385 179.0
WLSH2_k127_6213006_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000001854 138.0
WLSH2_k127_6213006_8 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.0000000000002497 70.0
WLSH2_k127_6244149_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 3.956e-211 665.0
WLSH2_k127_6244149_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 620.0
WLSH2_k127_6244149_10 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000005783 195.0
WLSH2_k127_6244149_11 Protein of unknown function (DUF2442) - - - 0.000000000000000000000008626 102.0
WLSH2_k127_6244149_12 PIN domain - - - 0.00000000000000000000006913 106.0
WLSH2_k127_6244149_13 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000001506 107.0
WLSH2_k127_6244149_15 Integral membrane sensor hybrid histidine kinase - - - 0.000000000006294 72.0
WLSH2_k127_6244149_16 SNARE associated Golgi protein - - - 0.0000000004807 68.0
WLSH2_k127_6244149_17 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000009696 54.0
WLSH2_k127_6244149_18 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0001034 49.0
WLSH2_k127_6244149_2 AAA ATPase, central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 476.0
WLSH2_k127_6244149_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 343.0
WLSH2_k127_6244149_4 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 338.0
WLSH2_k127_6244149_5 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 311.0
WLSH2_k127_6244149_6 metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 289.0
WLSH2_k127_6244149_7 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000004564 233.0
WLSH2_k127_6244149_8 Ribosomal RNA large subunit methyltransferase J K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000005694 229.0
WLSH2_k127_6244149_9 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000316 202.0
WLSH2_k127_6244355_0 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000004067 149.0
WLSH2_k127_6270044_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.363e-246 772.0
WLSH2_k127_6270044_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000003613 142.0
WLSH2_k127_6378987_0 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 448.0
WLSH2_k127_6378987_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 416.0
WLSH2_k127_6378987_10 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000002014 179.0
WLSH2_k127_6378987_11 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process K03361,K10260 GO:0000003,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007275,GO:0007548,GO:0008150,GO:0008593,GO:0009966,GO:0009968,GO:0010564,GO:0010639,GO:0010646,GO:0010648,GO:0010824,GO:0010826,GO:0010948,GO:0019899,GO:0019900,GO:0019901,GO:0022414,GO:0023051,GO:0023057,GO:0030424,GO:0031647,GO:0032501,GO:0032502,GO:0032886,GO:0033043,GO:0040028,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0044424,GO:0044464,GO:0045746,GO:0045786,GO:0046605,GO:0046606,GO:0046660,GO:0046983,GO:0048519,GO:0048523,GO:0048580,GO:0048583,GO:0048585,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051129,GO:0051239,GO:0051493,GO:0051494,GO:0051726,GO:0061062,GO:0065007,GO:0065008,GO:0070507,GO:0097458,GO:0120025,GO:2000026 - 0.00000000000000000000000000000000000000000000005638 196.0
WLSH2_k127_6378987_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000009695 147.0
WLSH2_k127_6378987_13 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000693 120.0
WLSH2_k127_6378987_14 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000004585 122.0
WLSH2_k127_6378987_15 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000464 112.0
WLSH2_k127_6378987_16 PFAM filamentation induced by cAMP protein Fic - - - 0.000000000000000000000179 100.0
WLSH2_k127_6378987_17 helix_turn_helix, mercury resistance - - - 0.0000000000000000305 86.0
WLSH2_k127_6378987_18 PFAM acylphosphatase K01512 - 3.6.1.7 0.0000000000001243 75.0
WLSH2_k127_6378987_19 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000003197 72.0
WLSH2_k127_6378987_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 373.0
WLSH2_k127_6378987_20 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000003169 68.0
WLSH2_k127_6378987_21 Outer membrane lipoprotein - - - 0.0002049 52.0
WLSH2_k127_6378987_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 370.0
WLSH2_k127_6378987_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 345.0
WLSH2_k127_6378987_5 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 312.0
WLSH2_k127_6378987_6 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001526 293.0
WLSH2_k127_6378987_7 PFAM Monogalactosyldiacylglycerol synthase K03429 - 2.4.1.315 0.00000000000000000000000000000000000000000000000000000000000000000000000001422 268.0
WLSH2_k127_6378987_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000004756 198.0
WLSH2_k127_6378987_9 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.0000000000000000000000000000000000000000000000000006198 192.0
WLSH2_k127_6390906_0 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 293.0
WLSH2_k127_6390906_1 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.000000000000000000000000002929 125.0
WLSH2_k127_6390906_2 - - - - 0.000000000005106 77.0
WLSH2_k127_6390906_3 PFAM Transposase K07481 - - 0.00000126 54.0
WLSH2_k127_6390906_8 - - - - 0.0003308 53.0
WLSH2_k127_6390906_9 Transposase IS200 like - - - 0.0004358 48.0
WLSH2_k127_6391296_1 - - - - 0.000000000000007773 89.0
WLSH2_k127_6391296_2 Parallel beta-helix repeats - - - 0.00000008939 65.0
WLSH2_k127_6391296_4 exo-alpha-(2->6)-sialidase activity K02388,K02396 - - 0.00001867 56.0
WLSH2_k127_6391296_5 polygalacturonase activity - - - 0.0005669 51.0
WLSH2_k127_6406202_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 542.0
WLSH2_k127_6406202_1 lipid A export permease ATP-binding protein MsbA K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 509.0
WLSH2_k127_6406202_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000004296 254.0
WLSH2_k127_6406202_11 phosphate acetyltransferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000004001 244.0
WLSH2_k127_6406202_12 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000007856 236.0
WLSH2_k127_6406202_13 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000087 235.0
WLSH2_k127_6406202_14 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000008623 190.0
WLSH2_k127_6406202_15 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000002327 178.0
WLSH2_k127_6406202_16 Ribosomal L28 family K02902 - - 0.000000000000000008861 84.0
WLSH2_k127_6406202_17 PAS domain K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000001421 90.0
WLSH2_k127_6406202_18 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.000000000000005412 77.0
WLSH2_k127_6406202_19 divalent heavy-metal cations transporter K16267 - - 0.000000000000008115 85.0
WLSH2_k127_6406202_2 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 427.0
WLSH2_k127_6406202_20 thiamine biosynthesis protein ThiS K03154 - - 0.000000002107 64.0
WLSH2_k127_6406202_21 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000009997 69.0
WLSH2_k127_6406202_22 long-chain fatty acid transport protein - - - 0.00004163 55.0
WLSH2_k127_6406202_23 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K02343,K03642,K08652,K13733,K14195,K20382 - 2.7.7.7,3.4.21.110 0.0003492 53.0
WLSH2_k127_6406202_3 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 392.0
WLSH2_k127_6406202_4 surface antigen (D15) K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 349.0
WLSH2_k127_6406202_5 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 342.0
WLSH2_k127_6406202_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 310.0
WLSH2_k127_6406202_7 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 301.0
WLSH2_k127_6406202_8 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000005171 269.0
WLSH2_k127_6406202_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005624 267.0
WLSH2_k127_647857_0 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 358.0
WLSH2_k127_647857_1 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000001511 161.0
WLSH2_k127_647857_2 Trehalose-phosphatase K16055 - 2.4.1.15,3.1.3.12 0.0000000000000000000000000000000718 136.0
WLSH2_k127_6522573_0 Transposase, Mutator family K07493 - - 0.00000000000000000000000000000000003943 149.0
WLSH2_k127_6522573_1 protein transport across the cell outer membrane - - - 0.0000000000000002534 87.0
WLSH2_k127_6522573_2 iron dependent repressor - - - 0.000000001693 66.0
WLSH2_k127_6579426_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 363.0
WLSH2_k127_6579426_1 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000002932 215.0
WLSH2_k127_6593962_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1040.0
WLSH2_k127_6593962_1 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 424.0
WLSH2_k127_6593962_10 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000000000000001148 93.0
WLSH2_k127_6593962_11 Domain of unknown function (DUF4340) - - - 0.00000000005817 74.0
WLSH2_k127_6593962_13 efflux transmembrane transporter activity - - - 0.00008344 54.0
WLSH2_k127_6593962_14 RND efflux system, outer membrane lipoprotein K18903 - - 0.000275 53.0
WLSH2_k127_6593962_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 325.0
WLSH2_k127_6593962_3 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002205 280.0
WLSH2_k127_6593962_4 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002084 272.0
WLSH2_k127_6593962_5 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000009127 238.0
WLSH2_k127_6593962_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000007207 182.0
WLSH2_k127_6593962_7 HAMP domain K07651 - 2.7.13.3 0.00000000000000000000000000000000000000004617 167.0
WLSH2_k127_6593962_8 Response regulator receiver domain - - - 0.00000000000000000000000008409 112.0
WLSH2_k127_6593962_9 Sigma-54 interaction domain protein K07712,K07714 - - 0.000000000000000003217 97.0
WLSH2_k127_6619629_0 DNA primase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 482.0
WLSH2_k127_6619629_1 sequence-specific DNA binding - - - 0.0000001174 59.0
WLSH2_k127_6622323_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 369.0
WLSH2_k127_6622323_1 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 340.0
WLSH2_k127_6622323_2 Transposase K07492 - - 0.0000000000000000000005317 97.0
WLSH2_k127_6622323_3 Transposase - - - 0.0000000000000002159 89.0
WLSH2_k127_6622323_4 Transposase - - - 0.00001574 49.0
WLSH2_k127_6671399_0 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 507.0
WLSH2_k127_6671399_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 472.0
WLSH2_k127_6671399_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000003941 192.0
WLSH2_k127_6671399_11 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.0000000000000000000000000000000000000004047 151.0
WLSH2_k127_6671399_12 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000254 140.0
WLSH2_k127_6671399_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000007258 125.0
WLSH2_k127_6671399_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000002459 104.0
WLSH2_k127_6671399_15 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000003254 96.0
WLSH2_k127_6671399_16 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000003235 68.0
WLSH2_k127_6671399_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 453.0
WLSH2_k127_6671399_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 315.0
WLSH2_k127_6671399_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 291.0
WLSH2_k127_6671399_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 312.0
WLSH2_k127_6671399_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001234 282.0
WLSH2_k127_6671399_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000017 273.0
WLSH2_k127_6671399_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000002541 207.0
WLSH2_k127_6671399_9 Belongs to the FPP GGPP synthase family K00805,K21275 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 0.00000000000000000000000000000000000000000000000003708 192.0
WLSH2_k127_668973_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.114e-309 988.0
WLSH2_k127_668973_1 Belongs to the glycosyl hydrolase 57 family - - - 1.995e-229 736.0
WLSH2_k127_668973_10 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 431.0
WLSH2_k127_668973_11 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 402.0
WLSH2_k127_668973_12 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 398.0
WLSH2_k127_668973_13 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 387.0
WLSH2_k127_668973_14 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 381.0
WLSH2_k127_668973_15 4-alpha-glucanotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 391.0
WLSH2_k127_668973_16 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 324.0
WLSH2_k127_668973_17 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007934 275.0
WLSH2_k127_668973_18 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008588 273.0
WLSH2_k127_668973_19 pfam abc K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002658 267.0
WLSH2_k127_668973_2 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.958e-211 679.0
WLSH2_k127_668973_20 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000005883 263.0
WLSH2_k127_668973_21 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001389 254.0
WLSH2_k127_668973_22 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001967 246.0
WLSH2_k127_668973_23 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000004089 248.0
WLSH2_k127_668973_24 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000779 228.0
WLSH2_k127_668973_25 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000007842 224.0
WLSH2_k127_668973_26 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.00000000000000000000000000000000000000000000000000000001069 205.0
WLSH2_k127_668973_27 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000001154 209.0
WLSH2_k127_668973_28 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000001442 199.0
WLSH2_k127_668973_29 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000003912 210.0
WLSH2_k127_668973_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 516.0
WLSH2_k127_668973_30 peptidase activity - - - 0.000000000000000000000000000000000000000000000005002 194.0
WLSH2_k127_668973_31 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000007722 177.0
WLSH2_k127_668973_32 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - - 0.00000000000000000000000000000000000000000006633 180.0
WLSH2_k127_668973_33 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000256 153.0
WLSH2_k127_668973_34 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000003299 150.0
WLSH2_k127_668973_35 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000000000000000000000006065 143.0
WLSH2_k127_668973_36 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000003278 137.0
WLSH2_k127_668973_37 CHASE3 domain - - - 0.00000000000000000001395 95.0
WLSH2_k127_668973_38 Haloacid dehalogenase-like hydrolase K07025,K20866 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050308 3.1.3.10 0.00000000000000002086 91.0
WLSH2_k127_668973_39 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000002811 94.0
WLSH2_k127_668973_4 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 485.0
WLSH2_k127_668973_40 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000006692 81.0
WLSH2_k127_668973_41 BetI-type transcriptional repressor, C-terminal - - - 0.000000000007691 73.0
WLSH2_k127_668973_42 - - - - 0.00000000001615 72.0
WLSH2_k127_668973_43 - K01992,K19341 - - 0.00000000003132 74.0
WLSH2_k127_668973_44 Thioredoxin-like [2Fe-2S] ferredoxin - - - 0.00000000007473 69.0
WLSH2_k127_668973_45 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000001638 65.0
WLSH2_k127_668973_46 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.000001888 50.0
WLSH2_k127_668973_47 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000225 57.0
WLSH2_k127_668973_48 Pectate lyase - - - 0.00002366 55.0
WLSH2_k127_668973_49 - - - - 0.0003641 43.0
WLSH2_k127_668973_5 PFAM Orn Lys Arg decarboxylase major K01582,K01585 - 4.1.1.18,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 459.0
WLSH2_k127_668973_6 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 447.0
WLSH2_k127_668973_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 449.0
WLSH2_k127_668973_8 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 441.0
WLSH2_k127_668973_9 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 423.0
WLSH2_k127_6695335_0 - - - - 0.00000000000001078 78.0
WLSH2_k127_6805404_0 Type III restriction enzyme res subunit K01156 - 3.1.21.5 0.0 1292.0
WLSH2_k127_6805404_1 DNA methylase K07316 - 2.1.1.72 0.0 1065.0
WLSH2_k127_6805404_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 366.0
WLSH2_k127_6805404_11 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 338.0
WLSH2_k127_6805404_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000004884 246.0
WLSH2_k127_6805404_13 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000002354 222.0
WLSH2_k127_6805404_14 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000001678 192.0
WLSH2_k127_6805404_15 TIGRFAM Addiction module toxin, Txe YoeB - - - 0.0000000000000000000000000000000000698 136.0
WLSH2_k127_6805404_16 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000000001363 130.0
WLSH2_k127_6805404_17 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000001131 126.0
WLSH2_k127_6805404_18 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000003812 115.0
WLSH2_k127_6805404_19 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03855 - - 0.0000000000000000000000000132 112.0
WLSH2_k127_6805404_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 4.544e-194 621.0
WLSH2_k127_6805404_20 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000000002571 110.0
WLSH2_k127_6805404_21 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000002098 114.0
WLSH2_k127_6805404_22 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000002298 99.0
WLSH2_k127_6805404_23 PFAM response regulator receiver - - - 0.000000000000000001844 89.0
WLSH2_k127_6805404_24 copG family - - - 0.00000000000000001139 85.0
WLSH2_k127_6805404_25 long-chain fatty acid transport protein - - - 0.00000000000007749 82.0
WLSH2_k127_6805404_26 - - - - 0.000000000007201 69.0
WLSH2_k127_6805404_27 COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.0005907 48.0
WLSH2_k127_6805404_3 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 605.0
WLSH2_k127_6805404_4 PFAM FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 581.0
WLSH2_k127_6805404_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 568.0
WLSH2_k127_6805404_6 Protein of unknown function (DUF1016) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 475.0
WLSH2_k127_6805404_7 Thi4 family K00313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 438.0
WLSH2_k127_6805404_8 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 396.0
WLSH2_k127_6805404_9 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 377.0
WLSH2_k127_6847953_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1351.0
WLSH2_k127_6847953_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.332e-194 613.0
WLSH2_k127_6847953_10 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 445.0
WLSH2_k127_6847953_11 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 438.0
WLSH2_k127_6847953_12 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 446.0
WLSH2_k127_6847953_13 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 379.0
WLSH2_k127_6847953_14 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 372.0
WLSH2_k127_6847953_15 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 338.0
WLSH2_k127_6847953_16 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 341.0
WLSH2_k127_6847953_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 329.0
WLSH2_k127_6847953_18 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 312.0
WLSH2_k127_6847953_19 ABC transporter K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 293.0
WLSH2_k127_6847953_2 GDP-mannose 4,6 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 612.0
WLSH2_k127_6847953_20 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 305.0
WLSH2_k127_6847953_21 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000333 296.0
WLSH2_k127_6847953_22 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001103 286.0
WLSH2_k127_6847953_23 cellulase activity K01179,K01183,K13381,K20276 - 3.2.1.14,3.2.1.17,3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002351 294.0
WLSH2_k127_6847953_24 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000987 276.0
WLSH2_k127_6847953_25 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000104 267.0
WLSH2_k127_6847953_26 Pfam:HipA_N K07154 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000152 252.0
WLSH2_k127_6847953_27 maltose O-acetyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000006662 232.0
WLSH2_k127_6847953_28 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002368 233.0
WLSH2_k127_6847953_29 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000004511 229.0
WLSH2_k127_6847953_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 581.0
WLSH2_k127_6847953_30 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000008722 240.0
WLSH2_k127_6847953_31 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000001137 216.0
WLSH2_k127_6847953_32 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000005007 208.0
WLSH2_k127_6847953_33 dehydratase K17865,K19659 - 4.2.1.119,4.2.1.55 0.00000000000000000000000000000000000000000000000000002349 192.0
WLSH2_k127_6847953_34 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000003624 190.0
WLSH2_k127_6847953_35 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000484 196.0
WLSH2_k127_6847953_36 mannose-6-phosphate isomerase, class I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000001789 177.0
WLSH2_k127_6847953_37 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000004053 159.0
WLSH2_k127_6847953_38 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000007407 156.0
WLSH2_k127_6847953_39 PFAM Phosphoribosyltransferase K02242 - - 0.0000000000000000000000000000000000001418 151.0
WLSH2_k127_6847953_4 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 587.0
WLSH2_k127_6847953_40 methyltransferase - - - 0.00000000000000000000000000000000002881 158.0
WLSH2_k127_6847953_41 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000005158 141.0
WLSH2_k127_6847953_42 Transcriptional regulator - - - 0.0000000000000000000000000007829 118.0
WLSH2_k127_6847953_43 response regulator, receiver K07658 - - 0.0000000000000000000000000014 116.0
WLSH2_k127_6847953_44 protein methyltransferase activity K02687 - - 0.000000000000000000000000001433 124.0
WLSH2_k127_6847953_45 of nitrite reductase and ring-hydroxylating K05710 - - 0.000000000000000000000000001839 115.0
WLSH2_k127_6847953_46 HipA N-terminal domain K07154 - 2.7.11.1 0.000000000000000000000000007513 113.0
WLSH2_k127_6847953_47 FeS assembly SUF system protein - - - 0.0000000000000000000000001871 109.0
WLSH2_k127_6847953_48 - - - - 0.00000000000000000001689 105.0
WLSH2_k127_6847953_49 sequence-specific DNA binding - - - 0.00000000000000000008151 90.0
WLSH2_k127_6847953_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 552.0
WLSH2_k127_6847953_50 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000005393 98.0
WLSH2_k127_6847953_51 Phage derived protein Gp49-like (DUF891) - - - 0.0000000003016 65.0
WLSH2_k127_6847953_52 Protein conserved in bacteria - - - 0.00000003112 66.0
WLSH2_k127_6847953_53 Helix-turn-helix domain - - - 0.0000009396 57.0
WLSH2_k127_6847953_54 penicillin-binding protein - - - 0.00000263 59.0
WLSH2_k127_6847953_55 ATPase, AAA superfamily K07133 - - 0.0001278 45.0
WLSH2_k127_6847953_56 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0001358 49.0
WLSH2_k127_6847953_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 475.0
WLSH2_k127_6847953_7 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 469.0
WLSH2_k127_6847953_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 454.0
WLSH2_k127_6847953_9 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 442.0
WLSH2_k127_6866170_0 Protein of unknown function (DUF3131) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 408.0
WLSH2_k127_6866170_1 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000001797 146.0
WLSH2_k127_6866170_2 Periplasmic binding protein domain - - - 0.00000000000000000000000000001129 133.0
WLSH2_k127_6866170_3 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000000003824 82.0
WLSH2_k127_6866170_4 long-chain fatty acid transport protein - - - 0.000000000000857 79.0
WLSH2_k127_6866170_5 Protein of unknown function (DUF3131) - - - 0.00000000002046 76.0
WLSH2_k127_6866170_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000051 70.0
WLSH2_k127_6866170_7 Cellulase (glycosyl hydrolase family 5) K19355 - 3.2.1.78 0.000003271 59.0
WLSH2_k127_6866170_9 hydrolase, family 9 K01179 - 3.2.1.4 0.0006789 51.0
WLSH2_k127_7041609_0 SNF2 family N-terminal domain - - - 0.0 1607.0
WLSH2_k127_7041609_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 331.0
WLSH2_k127_7041609_2 Putative DNA-binding domain K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 315.0
WLSH2_k127_7041609_3 regulation of methylation-dependent chromatin silencing K07454 - - 0.0000000000000000000000000000000000000000000000000000000000000008222 229.0
WLSH2_k127_7041609_4 KAP family P-loop domain - - - 0.000000000000000000000000002561 130.0
WLSH2_k127_7041609_5 Protein of unknown function (DUF1016) - - - 0.000000006949 68.0
WLSH2_k127_7041609_6 COG1525 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.0000000664 64.0
WLSH2_k127_7138544_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 5e-324 1026.0
WLSH2_k127_7138544_1 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 462.0
WLSH2_k127_7138544_10 CopG antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000000000002537 130.0
WLSH2_k127_7138544_11 COGs COG4771 Outer membrane receptor for ferrienterochelin and colicins K02014 - - 0.000000000000000000000000000178 133.0
WLSH2_k127_7138544_12 Periplasmic binding protein K02016 - - 0.0000000000000000000001895 103.0
WLSH2_k127_7138544_13 Outer membrane efflux protein - - - 0.000000000000000000001166 109.0
WLSH2_k127_7138544_14 Protein of unknown function (DUF2892) - - - 0.0000000000000009243 79.0
WLSH2_k127_7138544_15 - - - - 0.00000000003637 69.0
WLSH2_k127_7138544_16 - - - - 0.000000008477 64.0
WLSH2_k127_7138544_2 ATPase (AAA superfamily) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 454.0
WLSH2_k127_7138544_3 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 407.0
WLSH2_k127_7138544_4 MltA-interacting MipA family protein K07274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 334.0
WLSH2_k127_7138544_5 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 305.0
WLSH2_k127_7138544_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000001421 220.0
WLSH2_k127_7138544_7 PFAM ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000001421 201.0
WLSH2_k127_7138544_8 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000000002038 166.0
WLSH2_k127_7138544_9 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000000001002 139.0
WLSH2_k127_7234672_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 5.96e-311 977.0
WLSH2_k127_7234672_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 563.0
WLSH2_k127_7234672_2 ANTAR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 409.0
WLSH2_k127_7234672_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 394.0
WLSH2_k127_7234672_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000002456 227.0
WLSH2_k127_7234672_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000003175 157.0
WLSH2_k127_7234672_6 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000004004 130.0
WLSH2_k127_7234672_7 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000277 115.0
WLSH2_k127_7301866_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007136 282.0
WLSH2_k127_7301866_1 protein trimerization - - - 0.0000000000000000000004349 113.0
WLSH2_k127_7301866_2 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000002031 93.0
WLSH2_k127_7301866_3 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000001545 68.0
WLSH2_k127_7301866_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000002321 66.0
WLSH2_k127_7301866_5 Biopolymer transport protein ExbD/TolR K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000001351 62.0
WLSH2_k127_7301866_6 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000002726 61.0
WLSH2_k127_7301866_7 ompA family - - - 0.000004679 59.0
WLSH2_k127_7349418_0 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 434.0
WLSH2_k127_7349418_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000001829 236.0
WLSH2_k127_7349418_2 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.00000000000000000001246 101.0
WLSH2_k127_7349418_3 protein conserved in bacteria - - - 0.00000000000001168 76.0
WLSH2_k127_7349418_4 - - - - 0.0000000000001473 78.0
WLSH2_k127_7349418_5 ACT domain - - - 0.00000000001005 70.0
WLSH2_k127_7358008_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 484.0
WLSH2_k127_7358008_1 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008093 456.0
WLSH2_k127_7358008_10 small subunit K06282 - 1.12.99.6 0.000004553 55.0
WLSH2_k127_7358008_11 Winged helix-turn-helix domain (DUF2582) - - - 0.0002151 49.0
WLSH2_k127_7358008_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 329.0
WLSH2_k127_7358008_3 recombinase XerD K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000001191 228.0
WLSH2_k127_7358008_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000003382 145.0
WLSH2_k127_7358008_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000005012 145.0
WLSH2_k127_7358008_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000008406 108.0
WLSH2_k127_7358008_7 Domain of unknown function (DUF4115) - - - 0.0000000000000000002619 102.0
WLSH2_k127_7358008_8 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000005061 87.0
WLSH2_k127_7358008_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000009979 83.0
WLSH2_k127_7522361_0 CoA binding domain K09181 - - 0.0 1093.0
WLSH2_k127_7522361_1 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 593.0
WLSH2_k127_7522361_10 PFAM CheR methyltransferase, SAM binding domain K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000001592 236.0
WLSH2_k127_7522361_11 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000007392 238.0
WLSH2_k127_7522361_12 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000007816 234.0
WLSH2_k127_7522361_13 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660,K03406 - - 0.00000000000000000000000000000000000000000000000000000000004936 222.0
WLSH2_k127_7522361_14 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000000000000000000000000000009626 201.0
WLSH2_k127_7522361_15 PFAM NUDIX domain - - - 0.00000000000000000000000000000000000000000005355 168.0
WLSH2_k127_7522361_16 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000008376 147.0
WLSH2_k127_7522361_17 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000002412 131.0
WLSH2_k127_7522361_18 - - - - 0.0000000000000000000000000003949 128.0
WLSH2_k127_7522361_19 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000009634 128.0
WLSH2_k127_7522361_2 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 595.0
WLSH2_k127_7522361_20 cheY-homologous receiver domain K03413 - - 0.000000000000000000000006182 105.0
WLSH2_k127_7522361_21 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000152 110.0
WLSH2_k127_7522361_22 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000002932 96.0
WLSH2_k127_7522361_23 Domain of unknown function (DUF4149) - - - 0.0000000000000004074 86.0
WLSH2_k127_7522361_24 Histidine kinase - - - 0.0000000000000008124 91.0
WLSH2_k127_7522361_25 phosphorelay signal transduction system - - - 0.000000000000003534 80.0
WLSH2_k127_7522361_26 deoxyhypusine monooxygenase activity - - - 0.00002923 57.0
WLSH2_k127_7522361_27 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00003175 51.0
WLSH2_k127_7522361_3 transport protein K07085 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 523.0
WLSH2_k127_7522361_4 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 520.0
WLSH2_k127_7522361_5 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 387.0
WLSH2_k127_7522361_6 PFAM aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 347.0
WLSH2_k127_7522361_7 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 319.0
WLSH2_k127_7522361_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 308.0
WLSH2_k127_7522361_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000001478 250.0
WLSH2_k127_7537167_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.739e-313 985.0
WLSH2_k127_7537167_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.765e-295 925.0
WLSH2_k127_7537167_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000005462 169.0
WLSH2_k127_7537167_3 glucan 1,4-alpha-glucosidase activity - - - 0.000000000000000000000000000001971 138.0
WLSH2_k127_7537167_4 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000003252 98.0
WLSH2_k127_7597875_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.87e-294 930.0
WLSH2_k127_7597875_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 547.0
WLSH2_k127_7597875_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000002239 177.0
WLSH2_k127_7597875_11 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000006414 161.0
WLSH2_k127_7597875_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000001166 153.0
WLSH2_k127_7597875_13 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000002467 136.0
WLSH2_k127_7597875_14 Polysaccharide pyruvyl transferase - - - 0.00000000000000000003691 106.0
WLSH2_k127_7597875_15 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000691 53.0
WLSH2_k127_7597875_2 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 422.0
WLSH2_k127_7597875_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 410.0
WLSH2_k127_7597875_4 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 392.0
WLSH2_k127_7597875_5 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 323.0
WLSH2_k127_7597875_6 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 301.0
WLSH2_k127_7597875_7 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000002669 232.0
WLSH2_k127_7597875_8 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000003106 187.0
WLSH2_k127_7597875_9 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000003638 177.0
WLSH2_k127_7598961_0 DNA primase activity K02316,K17680 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000002341 264.0
WLSH2_k127_7677492_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 478.0
WLSH2_k127_7677492_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 402.0
WLSH2_k127_7677492_2 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000001569 240.0
WLSH2_k127_7677492_3 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000531 217.0
WLSH2_k127_7677492_4 Zn-dependent hydrolases of the - - - 0.0000000000000000000000000000000000000002576 160.0
WLSH2_k127_7677492_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000007341 103.0
WLSH2_k127_7677492_6 synthase K01719 - 4.2.1.75 0.000000000000433 75.0
WLSH2_k127_7697523_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1166.0
WLSH2_k127_7697523_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.515e-308 966.0
WLSH2_k127_7697523_10 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 415.0
WLSH2_k127_7697523_11 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 420.0
WLSH2_k127_7697523_12 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 382.0
WLSH2_k127_7697523_13 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 318.0
WLSH2_k127_7697523_14 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000004751 270.0
WLSH2_k127_7697523_15 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000004919 266.0
WLSH2_k127_7697523_16 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000632 273.0
WLSH2_k127_7697523_17 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008232 261.0
WLSH2_k127_7697523_18 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009308 246.0
WLSH2_k127_7697523_19 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000005184 244.0
WLSH2_k127_7697523_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.398e-265 835.0
WLSH2_k127_7697523_20 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000008055 206.0
WLSH2_k127_7697523_21 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000001294 192.0
WLSH2_k127_7697523_22 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000006413 158.0
WLSH2_k127_7697523_23 Domain of unknown function (DUF4912) K09942 - - 0.0000000000000000000000000000000000000001247 162.0
WLSH2_k127_7697523_24 GGDEF domain - - - 0.00000000000000000000000000000000000005913 155.0
WLSH2_k127_7697523_25 - - - - 0.00000000000000000000000000000000004368 144.0
WLSH2_k127_7697523_26 COG0607 Rhodanese-related sulfurtransferase - - - 0.00000000000000000000009957 103.0
WLSH2_k127_7697523_27 Belongs to the ompA family K03286 - - 0.0000000000000000000001047 108.0
WLSH2_k127_7697523_28 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.000000000000000000017 106.0
WLSH2_k127_7697523_29 UV-endonuclease UvdE - - - 0.000000000000001665 89.0
WLSH2_k127_7697523_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.907e-253 807.0
WLSH2_k127_7697523_30 general secretion pathway protein K02456 - - 0.00000000125 64.0
WLSH2_k127_7697523_31 HD domain K07023 - - 0.000000003247 72.0
WLSH2_k127_7697523_32 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000001036 60.0
WLSH2_k127_7697523_33 Forkhead associated domain - - - 0.0000007962 60.0
WLSH2_k127_7697523_34 Hemerythrin - - - 0.00001073 53.0
WLSH2_k127_7697523_36 - - - - 0.00003558 54.0
WLSH2_k127_7697523_4 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 5.871e-217 685.0
WLSH2_k127_7697523_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.448e-201 640.0
WLSH2_k127_7697523_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 588.0
WLSH2_k127_7697523_7 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 530.0
WLSH2_k127_7697523_8 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 503.0
WLSH2_k127_7697523_9 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 449.0
WLSH2_k127_7744371_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 365.0
WLSH2_k127_7744371_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 306.0
WLSH2_k127_7744371_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000002595 70.0
WLSH2_k127_7744371_3 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.0000021 59.0
WLSH2_k127_7753477_0 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001631 260.0
WLSH2_k127_7753477_1 PFAM glycoside hydrolase family 3 K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000007801 261.0
WLSH2_k127_7753477_2 BadF BadG BcrA BcrD - - - 0.0000003493 61.0
WLSH2_k127_776504_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1132.0
WLSH2_k127_776504_1 Heat shock 70 kDa protein K04043 - - 8.645e-209 666.0
WLSH2_k127_776504_10 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 361.0
WLSH2_k127_776504_11 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 344.0
WLSH2_k127_776504_12 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 321.0
WLSH2_k127_776504_13 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 288.0
WLSH2_k127_776504_14 ADP-glyceromanno-heptose 6-epimerase activity K03274 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901576,GO:1903509 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 292.0
WLSH2_k127_776504_15 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001729 281.0
WLSH2_k127_776504_16 Tetrapyrrole (Corrin/Porphyrin) Methylases K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000005328 272.0
WLSH2_k127_776504_17 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000003773 245.0
WLSH2_k127_776504_18 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000001915 214.0
WLSH2_k127_776504_19 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000004171 205.0
WLSH2_k127_776504_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 2.018e-195 634.0
WLSH2_k127_776504_20 DJ-1/PfpI family K03152,K05520,K05687 - 3.5.1.124 0.00000000000000000000000000000000000000008905 157.0
WLSH2_k127_776504_21 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000000000149 140.0
WLSH2_k127_776504_22 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000004583 146.0
WLSH2_k127_776504_23 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000172 120.0
WLSH2_k127_776504_24 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000001719 117.0
WLSH2_k127_776504_25 Predicted membrane protein (DUF2061) - - - 0.000000000000000000000122 100.0
WLSH2_k127_776504_26 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000003041 101.0
WLSH2_k127_776504_27 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000003595 98.0
WLSH2_k127_776504_28 HD superfamily hydrolase involved in NAD metabolism - - - 0.0000000000000000006183 97.0
WLSH2_k127_776504_29 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000413 82.0
WLSH2_k127_776504_3 Sulfite reductase beta subunit (hemoprotein) K00381,K00392 - 1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 578.0
WLSH2_k127_776504_30 PFAM Cyclic nucleotide-binding K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000007837 93.0
WLSH2_k127_776504_31 Transcriptional regulator - - - 0.00000000000002057 80.0
WLSH2_k127_776504_32 Helix-turn-helix - - - 0.0000000000005512 72.0
WLSH2_k127_776504_33 Tetratricopeptide repeat protein - - - 0.000000000001112 78.0
WLSH2_k127_776504_34 PFAM UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000007212 61.0
WLSH2_k127_776504_4 PFAM Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 518.0
WLSH2_k127_776504_5 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 509.0
WLSH2_k127_776504_6 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 461.0
WLSH2_k127_776504_7 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 447.0
WLSH2_k127_776504_8 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007413 404.0
WLSH2_k127_776504_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 368.0
WLSH2_k127_7825514_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 398.0
WLSH2_k127_7829334_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 326.0
WLSH2_k127_7829334_1 NUBPL iron-transfer P-loop NTPase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 305.0
WLSH2_k127_7829334_2 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 310.0
WLSH2_k127_7829334_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001407 265.0
WLSH2_k127_7829334_4 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000007625 217.0
WLSH2_k127_7829334_5 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000001433 181.0
WLSH2_k127_7829334_6 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000003885 149.0
WLSH2_k127_7876317_0 C-terminal domain of CHU protein family - - - 0.00005097 56.0
WLSH2_k127_79635_0 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 399.0
WLSH2_k127_79635_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 328.0
WLSH2_k127_79635_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000001201 151.0
WLSH2_k127_79635_3 Prephenate dehydrogenase K00210,K00220,K04517 - 1.3.1.12,1.3.1.43 0.000000000000000000000000001472 121.0
WLSH2_k127_8057243_0 Phage prohead protease, HK97 family - - - 0.000000000000000000000000008503 117.0
WLSH2_k127_8057243_1 Phage capsid family - - - 0.000000000000000001392 100.0
WLSH2_k127_8073521_0 Protein of unknown function (DUF2793) - - - 0.0000000000000000000000000000000000000000003911 167.0
WLSH2_k127_8073521_1 - - - - 0.0000000000000000000000000000000005323 134.0
WLSH2_k127_8073521_2 cephalosporin hydroxylase - - - 0.000000000000000000000000001732 128.0
WLSH2_k127_8073521_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000006308 117.0
WLSH2_k127_8073521_4 N-acetylgalactosaminyltransferase K00710 GO:0003674,GO:0003824,GO:0004653,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005795,GO:0005975,GO:0008150,GO:0008152,GO:0008194,GO:0008376,GO:0009058,GO:0009311,GO:0009312,GO:0012505,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0031984,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0098791,GO:0140096,GO:1901576 2.4.1.41 0.00000002621 66.0
WLSH2_k127_8073521_5 Domain of unknown function (DUF4468) with TBP-like fold - - - 0.00000003619 60.0
WLSH2_k127_8073521_7 - - - - 0.000004834 59.0
WLSH2_k127_8101831_0 Phage Tail Collar Domain - - - 0.000000000000000000000000000005981 128.0
WLSH2_k127_8180463_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.009e-235 744.0
WLSH2_k127_8180463_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 514.0
WLSH2_k127_8180463_10 PTS system K02795 - - 0.0000000000004245 78.0
WLSH2_k127_8180463_11 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00005725 48.0
WLSH2_k127_8180463_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002886 287.0
WLSH2_k127_8180463_3 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001211 272.0
WLSH2_k127_8180463_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000002016 199.0
WLSH2_k127_8180463_5 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000001155 145.0
WLSH2_k127_8180463_6 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.0000000000000000000000000003082 128.0
WLSH2_k127_8180463_7 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000000003651 115.0
WLSH2_k127_8180463_8 phosphocarrier protein HPr K11189 - - 0.000000000000000000005536 96.0
WLSH2_k127_8180463_9 system, fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000002294 89.0
WLSH2_k127_8233303_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 307.0
WLSH2_k127_8233303_1 single-stranded nucleic acid binding R3H K06346 - - 0.0000000000000000001499 96.0
WLSH2_k127_8282879_0 pilus organization K12132 - 2.7.11.1 0.0000004505 60.0
WLSH2_k127_8284529_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.338e-255 802.0
WLSH2_k127_8284529_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 532.0
WLSH2_k127_8284529_10 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.00000000000000000000000000000000000000008597 156.0
WLSH2_k127_8284529_11 Domain of unknown function DUF302 - - - 0.00000000000000000000001765 105.0
WLSH2_k127_8284529_12 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000003811 109.0
WLSH2_k127_8284529_13 Bacterial Ig-like domain (group 1) - - - 0.0000000000006322 83.0
WLSH2_k127_8284529_14 Hep Hag repeat protein - - - 0.00000000003054 76.0
WLSH2_k127_8284529_15 O-antigen polymerase K18814 - - 0.00000000005979 76.0
WLSH2_k127_8284529_16 O-antigen polymerase K18814 - - 0.000000000268 74.0
WLSH2_k127_8284529_17 Chaperone of endosialidase K21449 - - 0.00008129 55.0
WLSH2_k127_8284529_2 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 518.0
WLSH2_k127_8284529_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 385.0
WLSH2_k127_8284529_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 357.0
WLSH2_k127_8284529_5 PFAM type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 335.0
WLSH2_k127_8284529_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 295.0
WLSH2_k127_8284529_7 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006669 287.0
WLSH2_k127_8284529_8 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000001328 216.0
WLSH2_k127_8284529_9 Hpt domain - - - 0.00000000000000000000000000000000000000000000001162 193.0
WLSH2_k127_8303232_0 Cellobiose phosphorylase K00702 - 2.4.1.20 2.287e-209 678.0
WLSH2_k127_8303232_1 Belongs to the glycosyl hydrolase 35 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 421.0
WLSH2_k127_8303232_10 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000108 71.0
WLSH2_k127_8303232_11 - - - - 0.00000000001197 68.0
WLSH2_k127_8303232_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 323.0
WLSH2_k127_8303232_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000005907 228.0
WLSH2_k127_8303232_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000003121 209.0
WLSH2_k127_8303232_5 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000001857 190.0
WLSH2_k127_8303232_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000006924 159.0
WLSH2_k127_8303232_7 ABC transporter - - - 0.00000000000000000000000000000000000000001173 162.0
WLSH2_k127_8303232_8 HD domain - - - 0.00000000000000000000000000000000000004478 156.0
WLSH2_k127_8303232_9 SpoVT / AbrB like domain K07172 - - 0.000000000000000002226 87.0
WLSH2_k127_8330729_0 Saccharopine dehydrogenase C-terminal domain - - - 9.549e-215 671.0
WLSH2_k127_8330729_1 RecQ zinc-binding K03654 - 3.6.4.12 1.197e-194 620.0
WLSH2_k127_8330729_10 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000005818 125.0
WLSH2_k127_8330729_11 Protein of unknown function (DUF2492) - - - 0.00000000000000000000001789 101.0
WLSH2_k127_8330729_12 - - - - 0.0000000000000000000001115 115.0
WLSH2_k127_8330729_13 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000007974 94.0
WLSH2_k127_8330729_2 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 489.0
WLSH2_k127_8330729_3 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 494.0
WLSH2_k127_8330729_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 464.0
WLSH2_k127_8330729_5 radical SAM domain protein K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 459.0
WLSH2_k127_8330729_6 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 344.0
WLSH2_k127_8330729_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001435 269.0
WLSH2_k127_8330729_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000002194 246.0
WLSH2_k127_8330729_9 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000003982 181.0
WLSH2_k127_8358354_0 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004591 298.0
WLSH2_k127_8358354_1 OB-fold nucleic acid binding domain K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000003479 228.0
WLSH2_k127_8358354_2 UvrD REP helicase K16898 - 3.6.4.12 0.0000000000000000000000000000000000000006576 168.0
WLSH2_k127_8358354_3 methyltransferase - - - 0.0000000000000000000000000000000008658 142.0
WLSH2_k127_8358354_4 Exonuclease VII small subunit K03602 - 3.1.11.6 0.00000003585 59.0
WLSH2_k127_8358354_5 COG0457 FOG TPR repeat - - - 0.0009348 52.0
WLSH2_k127_8379363_0 Type III restriction protein res subunit K01153 - 3.1.21.3 0.0 1135.0
WLSH2_k127_8379363_1 COG0286 Type I restriction-modification system methyltransferase subunit K03427 - 2.1.1.72 4.068e-239 746.0
WLSH2_k127_8379363_10 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000001341 66.0
WLSH2_k127_8379363_2 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 385.0
WLSH2_k127_8379363_4 - - - - 0.00000000000000000000000000001903 128.0
WLSH2_k127_8379363_6 - - - - 0.00000000000000000001026 103.0
WLSH2_k127_8379363_8 nuclease activity - - - 0.000000001085 68.0
WLSH2_k127_8379363_9 COG1525 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.000000004741 66.0
WLSH2_k127_8407516_0 DNA primase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 479.0
WLSH2_k127_8407516_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000003681 210.0
WLSH2_k127_8407516_2 recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000003715 198.0
WLSH2_k127_8407516_3 Nucleotidyltransferase - - - 0.0000000002111 68.0
WLSH2_k127_8407516_4 sequence-specific DNA binding - - - 0.000000002796 64.0
WLSH2_k127_8438194_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 484.0
WLSH2_k127_8438194_1 Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA) K00209 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.44,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 333.0
WLSH2_k127_8438194_2 glycosyl transferase family 2 K00721,K20534 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 320.0
WLSH2_k127_8438194_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000001855 199.0
WLSH2_k127_8438194_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000002087 190.0
WLSH2_k127_8438194_5 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000002374 120.0
WLSH2_k127_8438194_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000101 92.0
WLSH2_k127_8438194_7 Protein SSUH2 homolog - - - 0.00001024 59.0
WLSH2_k127_8445202_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 438.0
WLSH2_k127_8445202_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 377.0
WLSH2_k127_8445202_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000005907 228.0
WLSH2_k127_8445202_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000001833 173.0
WLSH2_k127_8506163_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 442.0
WLSH2_k127_8506163_1 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000003848 181.0
WLSH2_k127_8506163_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000001422 78.0
WLSH2_k127_8539822_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 399.0
WLSH2_k127_8539822_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 402.0
WLSH2_k127_8539822_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 323.0
WLSH2_k127_8539822_3 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004075 274.0
WLSH2_k127_8539822_4 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000003628 231.0
WLSH2_k127_8539822_5 Bifunctional nuclease K08999 - - 0.000000000000000000000000000006469 125.0
WLSH2_k127_8539822_6 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002763 118.0
WLSH2_k127_8539822_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000008823 96.0
WLSH2_k127_8539822_8 Virulence factor Mce family protein K02067 - - 0.000000000000000000006027 107.0
WLSH2_k127_8731912_0 IMP dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 313.0
WLSH2_k127_8731912_1 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000898 241.0
WLSH2_k127_892248_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 - 2.4.1.321 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 568.0
WLSH2_k127_892248_1 Transposase DDE domain - - - 0.000000009679 57.0
WLSH2_k127_89382_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001897 282.0
WLSH2_k127_89382_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000008841 234.0
WLSH2_k127_89382_10 O-antigen ligase like membrane protein - - - 0.000000000000000000001591 108.0
WLSH2_k127_89382_11 Phospholipid methyltransferase - - - 0.00000000000000000001476 98.0
WLSH2_k127_89382_12 integral membrane protein - - - 0.0000000000002508 78.0
WLSH2_k127_89382_2 PFAM glycosyl transferase family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000253 207.0
WLSH2_k127_89382_3 Glycosyltransferase, group 2 family protein - - - 0.00000000000000000000000000000000000000000000000000004153 200.0
WLSH2_k127_89382_4 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000003142 185.0
WLSH2_k127_89382_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000004288 192.0
WLSH2_k127_89382_6 Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.00000000000000000000000000000000000000000000001169 184.0
WLSH2_k127_89382_7 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000001249 179.0
WLSH2_k127_89382_8 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000003033 166.0
WLSH2_k127_89382_9 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000009086 164.0
WLSH2_k127_8939505_0 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007115 274.0
WLSH2_k127_8939505_1 HI0933-like protein K10210 - 1.14.99.44 0.00000000000000000000000000000000000000000000000000000000000000003272 224.0
WLSH2_k127_8939505_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000001495 243.0
WLSH2_k127_8939505_3 Transposase - - - 0.0000000000000000000000000000000000000000000000000000006709 207.0
WLSH2_k127_8939505_4 carotenoid biosynthetic process K10212 - - 0.000000000000000000000000000001264 133.0
WLSH2_k127_8939505_5 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.000000000000000000000003229 111.0
WLSH2_k127_8939505_6 Transposase DDE domain - - - 0.00000001502 58.0
WLSH2_k127_8939505_7 FlgD Ig-like domain - - - 0.0009684 46.0
WLSH2_k127_897743_0 Bacterial Ig-like domain (group 1) - - - 0.0000004299 63.0
WLSH2_k127_897743_1 Lamin Tail Domain - - - 0.000001503 55.0
WLSH2_k127_897743_2 - - - - 0.00009721 55.0
WLSH2_k127_9120168_0 restriction endonuclease K07448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 364.0
WLSH2_k127_9120168_1 Bacterial Ig-like domain (group 3) - - - 0.00000000001207 81.0
WLSH2_k127_9120168_2 SMART Hedgehog intein hint domain protein - - - 0.0000006929 66.0
WLSH2_k127_9229382_0 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 552.0
WLSH2_k127_9229382_1 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 366.0
WLSH2_k127_9229382_2 ATPase (AAA superfamily) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004848 275.0
WLSH2_k127_9229382_3 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000007974 190.0
WLSH2_k127_9229382_4 Protein-disulfide isomerase - - - 0.000000000000000000000000000003564 127.0
WLSH2_k127_9229382_5 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000001761 89.0
WLSH2_k127_9229382_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000001943 79.0
WLSH2_k127_9229382_7 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000002676 70.0
WLSH2_k127_9229382_8 Methylamine utilization protein MauE - - - 0.0002356 53.0
WLSH2_k127_9263311_0 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 405.0
WLSH2_k127_9263311_1 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 347.0
WLSH2_k127_9263311_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 329.0
WLSH2_k127_9263311_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 304.0
WLSH2_k127_9263311_4 Poly A polymerase head domain K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000014 276.0
WLSH2_k127_9263311_5 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000009076 244.0
WLSH2_k127_9263311_6 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000003651 218.0
WLSH2_k127_929160_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.371e-218 698.0
WLSH2_k127_929160_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000004683 243.0
WLSH2_k127_929160_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000008527 209.0
WLSH2_k127_929160_3 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000008316 129.0
WLSH2_k127_929160_4 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000005848 133.0
WLSH2_k127_929160_5 DNA protecting protein DprA K04096 - - 0.00000000000001258 78.0
WLSH2_k127_9355980_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 541.0
WLSH2_k127_9355980_1 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 438.0
WLSH2_k127_9355980_2 PFAM Outer membrane efflux protein - - - 0.000000001124 66.0
WLSH2_k127_9410154_0 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 555.0
WLSH2_k127_9410154_1 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 524.0
WLSH2_k127_9410154_10 Transcriptional regulator K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000001979 91.0
WLSH2_k127_9410154_11 Phospholipase D. Active site motifs. - - - 0.0000000000000001848 93.0
WLSH2_k127_9410154_12 Histidine kinase K02660,K11525 - - 0.0000000000000005066 87.0
WLSH2_k127_9410154_13 PFAM Fic DOC family - - - 0.0000001432 56.0
WLSH2_k127_9410154_2 Alternative oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 284.0
WLSH2_k127_9410154_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006057 291.0
WLSH2_k127_9410154_4 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000008789 228.0
WLSH2_k127_9410154_5 Cytochrome C biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000007218 203.0
WLSH2_k127_9410154_6 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000000223 151.0
WLSH2_k127_9410154_7 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000000002478 142.0
WLSH2_k127_9410154_8 - - - - 0.00000000000000000000000000005739 123.0
WLSH2_k127_9410154_9 Thioredoxin domain - - - 0.00000000000000000000000000006329 117.0
WLSH2_k127_9410778_0 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 403.0
WLSH2_k127_9410778_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 384.0
WLSH2_k127_9410778_10 endo-1,4-beta-xylanase activity - - - 0.00000000000000002266 93.0
WLSH2_k127_9410778_11 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000001356 61.0
WLSH2_k127_9410778_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 377.0
WLSH2_k127_9410778_3 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 353.0
WLSH2_k127_9410778_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 300.0
WLSH2_k127_9410778_5 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002156 279.0
WLSH2_k127_9410778_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008834 258.0
WLSH2_k127_9410778_7 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000001667 205.0
WLSH2_k127_9410778_8 Thioredoxin - - - 0.000000000000000000000000000000000001948 145.0
WLSH2_k127_9410778_9 Domain of unknown function (DUF4266) - - - 0.000000000000000000000006086 103.0
WLSH2_k127_9414784_0 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 314.0
WLSH2_k127_9414784_1 ABC transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 293.0
WLSH2_k127_9414784_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000403 280.0
WLSH2_k127_9414784_3 Abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001241 268.0
WLSH2_k127_942552_0 long-chain fatty acid transporting porin activity - - - 0.00000003281 65.0
WLSH2_k127_942552_1 - - - - 0.000003874 53.0
WLSH2_k127_942552_2 PFAM Protein kinase domain K08884 - 2.7.11.1 0.00000473 59.0
WLSH2_k127_942552_3 Chaperone of endosialidase - - - 0.00007076 54.0
WLSH2_k127_9470366_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 1.565e-311 970.0
WLSH2_k127_9470366_1 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 332.0
WLSH2_k127_9470366_10 - - - - 0.0000000008608 67.0
WLSH2_k127_9470366_2 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003298 290.0
WLSH2_k127_9470366_3 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001146 260.0
WLSH2_k127_9470366_4 Diacylglycerol kinase catalytic domain (presumed) - - - 0.000000000000000000000000000000000000000000000000000000005232 209.0
WLSH2_k127_9470366_5 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000003272 170.0
WLSH2_k127_9470366_6 - - - - 0.00000000000000000000000000000000002534 139.0
WLSH2_k127_9470366_7 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000000005779 122.0
WLSH2_k127_9470366_8 Transcriptional regulator - - - 0.00000000000000000003285 96.0
WLSH2_k127_9470366_9 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000126 81.0
WLSH2_k127_9470470_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 514.0
WLSH2_k127_949482_0 Domain of unknown function DUF11 - - - 0.00000000000000003956 99.0
WLSH2_k127_949482_1 PFAM SMP-30 Gluconolaconase - - - 0.000000005398 60.0
WLSH2_k127_9500122_0 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000001847 170.0
WLSH2_k127_9500122_1 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000001235 94.0
WLSH2_k127_9500122_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000002124 77.0
WLSH2_k127_9500122_3 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000002173 61.0
WLSH2_k127_9500122_4 TonB C terminal K03832 - - 0.0001378 53.0
WLSH2_k127_9500122_5 ompA family - - - 0.0003121 52.0
WLSH2_k127_9509825_0 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 382.0
WLSH2_k127_9509825_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000706 270.0
WLSH2_k127_9509825_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002354 194.0
WLSH2_k127_9509825_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000024 190.0
WLSH2_k127_9509825_4 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000001464 186.0
WLSH2_k127_9509825_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000007883 179.0
WLSH2_k127_9509825_6 VIT family - - - 0.000000000000000000000000002618 124.0
WLSH2_k127_9509825_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000004304 78.0
WLSH2_k127_9509825_8 Aerotolerance regulator N-terminal - - - 0.0000000001829 71.0
WLSH2_k127_9509825_9 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000001843 59.0
WLSH2_k127_9619094_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 3.572e-303 960.0
WLSH2_k127_9619094_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 582.0
WLSH2_k127_9619094_10 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000344 108.0
WLSH2_k127_9619094_11 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000006203 68.0
WLSH2_k127_9619094_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 373.0
WLSH2_k127_9619094_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 324.0
WLSH2_k127_9619094_4 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 328.0
WLSH2_k127_9619094_5 PFAM Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 289.0
WLSH2_k127_9619094_6 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004518 281.0
WLSH2_k127_9619094_7 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000004626 240.0
WLSH2_k127_9619094_8 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000007661 124.0
WLSH2_k127_9619094_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000004693 107.0
WLSH2_k127_9637526_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 517.0
WLSH2_k127_9637526_1 FIST C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 305.0
WLSH2_k127_9637526_2 COG1874 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000006751 239.0
WLSH2_k127_9637526_3 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000002408 155.0
WLSH2_k127_9638442_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.116e-202 655.0
WLSH2_k127_9638442_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 379.0
WLSH2_k127_9638442_10 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000006194 101.0
WLSH2_k127_9638442_11 Aerotolerance regulator N-terminal - - - 0.0000000000000000003778 100.0
WLSH2_k127_9638442_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000006715 72.0
WLSH2_k127_9638442_13 Peptidase MA superfamily - - - 0.00000001476 65.0
WLSH2_k127_9638442_14 Right handed beta helix region - - - 0.000003676 59.0
WLSH2_k127_9638442_15 Belongs to the bacterial solute-binding protein 9 family - - - 0.000007017 60.0
WLSH2_k127_9638442_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 314.0
WLSH2_k127_9638442_3 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000001081 227.0
WLSH2_k127_9638442_4 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000005295 205.0
WLSH2_k127_9638442_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000001818 196.0
WLSH2_k127_9638442_6 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000008017 198.0
WLSH2_k127_9638442_7 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000006042 180.0
WLSH2_k127_9638442_8 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000564 149.0
WLSH2_k127_9638442_9 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000001416 138.0
WLSH2_k127_9698213_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.294e-248 791.0
WLSH2_k127_9698213_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.459e-215 683.0
WLSH2_k127_9698213_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 531.0
WLSH2_k127_9698213_3 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 406.0
WLSH2_k127_9698213_4 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 369.0
WLSH2_k127_9698213_5 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 351.0
WLSH2_k127_9698213_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001612 265.0
WLSH2_k127_9698213_7 ORF6N domain - - - 0.000000000000000000000000000000000000000000007834 168.0
WLSH2_k127_9698213_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000002596 85.0
WLSH2_k127_9716377_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.323e-254 811.0
WLSH2_k127_9716377_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 322.0
WLSH2_k127_9716377_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000001922 239.0
WLSH2_k127_9716377_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000001244 134.0
WLSH2_k127_9770000_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 434.0
WLSH2_k127_9770000_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000008316 107.0
WLSH2_k127_9794560_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 447.0
WLSH2_k127_9794560_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 340.0
WLSH2_k127_9794560_10 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000001184 201.0
WLSH2_k127_9794560_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001389 181.0
WLSH2_k127_9794560_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000003006 172.0
WLSH2_k127_9794560_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000001279 171.0
WLSH2_k127_9794560_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000003173 165.0
WLSH2_k127_9794560_15 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000009673 167.0
WLSH2_k127_9794560_16 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000003511 145.0
WLSH2_k127_9794560_17 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000007287 149.0
WLSH2_k127_9794560_18 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000003598 136.0
WLSH2_k127_9794560_19 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000159 133.0
WLSH2_k127_9794560_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 306.0
WLSH2_k127_9794560_20 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000001348 125.0
WLSH2_k127_9794560_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000003258 108.0
WLSH2_k127_9794560_22 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000005813 108.0
WLSH2_k127_9794560_23 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000001641 96.0
WLSH2_k127_9794560_24 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000006352 97.0
WLSH2_k127_9794560_25 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000002031 91.0
WLSH2_k127_9794560_26 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000004304 78.0
WLSH2_k127_9794560_27 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000001198 64.0
WLSH2_k127_9794560_28 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000003482 59.0
WLSH2_k127_9794560_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001143 251.0
WLSH2_k127_9794560_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000002731 242.0
WLSH2_k127_9794560_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000006436 226.0
WLSH2_k127_9794560_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002484 229.0
WLSH2_k127_9794560_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001797 208.0
WLSH2_k127_9794560_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000002507 210.0
WLSH2_k127_9794560_9 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000001068 203.0
WLSH2_k127_9895362_0 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000002515 250.0
WLSH2_k127_9895362_1 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000002393 198.0
WLSH2_k127_9895362_2 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.000000000000000000000000006701 119.0
WLSH2_k127_9895362_3 cell adhesion K02650,K02682 - - 0.000000005646 64.0
WLSH2_k127_9895362_4 YaeQ protein - - - 0.000001954 56.0
WLSH2_k127_9987305_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.92e-293 924.0
WLSH2_k127_9987305_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.894e-216 683.0
WLSH2_k127_9987305_10 HD domain - - - 0.000000000000000000000000000000000000000000000000000006514 205.0
WLSH2_k127_9987305_11 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000004207 188.0
WLSH2_k127_9987305_12 - - - - 0.0000000000000000000000000000000000625 140.0
WLSH2_k127_9987305_13 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000002234 72.0
WLSH2_k127_9987305_14 LPP20 lipoprotein - - - 0.0000003723 62.0
WLSH2_k127_9987305_15 lyase activity - - - 0.00001953 56.0
WLSH2_k127_9987305_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 435.0
WLSH2_k127_9987305_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 433.0
WLSH2_k127_9987305_4 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 400.0
WLSH2_k127_9987305_5 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 346.0
WLSH2_k127_9987305_6 PFAM Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 307.0
WLSH2_k127_9987305_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000005533 237.0
WLSH2_k127_9987305_8 protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000000000000005414 239.0
WLSH2_k127_9987305_9 Peptidoglycan-synthase activator LpoB K07337 - - 0.00000000000000000000000000000000000000000000000000000000000004267 220.0