Overview

ID MAG04204
Name WLSH2_bin.29
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Omnitrophota
Class Koll11
Order Velamenicoccales
Family Velamenicoccaceae
Genus
Species
Assembly information
Completeness (%) 92.02
Contamination (%) 0.25
GC content (%) 51.0
N50 (bp) 19,295
Genome size (bp) 1,770,058

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1485

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10145467_0 4-alpha-glucanotransferase - - - 0.00000001556 70.0
WLSH2_k127_10145467_1 TIGRFAM HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.00000002048 69.0
WLSH2_k127_1023904_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000003303 241.0
WLSH2_k127_1023904_1 PFAM metallophosphoesterase K07098 - - 0.000000000000000000000000000000002171 142.0
WLSH2_k127_1023904_2 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.000000000000000000000000000004029 137.0
WLSH2_k127_10397878_0 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000004147 183.0
WLSH2_k127_10397878_1 Belongs to the GSP D family K02666 - - 0.00000000000000000000000000000000000000003103 170.0
WLSH2_k127_10397878_2 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.000000000000000000000000000001127 137.0
WLSH2_k127_10397878_3 TPR repeat - - - 0.00001727 55.0
WLSH2_k127_10452935_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000005874 232.0
WLSH2_k127_10452935_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000002307 134.0
WLSH2_k127_10452935_2 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.0000000000000000000000000006349 116.0
WLSH2_k127_10452935_3 Peptidase, M23 - - - 0.000000000000000000000002313 112.0
WLSH2_k127_10452935_4 PFAM Archaeal ATPase - - - 0.00000000000003429 86.0
WLSH2_k127_10455305_0 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000009262 221.0
WLSH2_k127_10455305_1 Haloacid dehalogenase-like hydrolase K01838 - 5.4.2.6 0.0000000000000000000000000000000000000009207 156.0
WLSH2_k127_10455305_2 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000007318 132.0
WLSH2_k127_10455305_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000005589 81.0
WLSH2_k127_10744172_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000106 291.0
WLSH2_k127_10744172_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000001346 207.0
WLSH2_k127_10849864_0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000002227 210.0
WLSH2_k127_10849864_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000001244 132.0
WLSH2_k127_10849864_2 OsmC-like protein K09136 - - 0.0000000000000000000000003532 109.0
WLSH2_k127_10849864_3 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000001643 72.0
WLSH2_k127_10886735_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 560.0
WLSH2_k127_10886735_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 534.0
WLSH2_k127_10886735_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000001723 176.0
WLSH2_k127_10886735_11 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000893 162.0
WLSH2_k127_10886735_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000002062 169.0
WLSH2_k127_10886735_13 - - - - 0.000000000000000000000000000000000000154 145.0
WLSH2_k127_10886735_14 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000001205 132.0
WLSH2_k127_10886735_15 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000000000000000000004092 117.0
WLSH2_k127_10886735_16 - - - - 0.000000000006545 70.0
WLSH2_k127_10886735_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 479.0
WLSH2_k127_10886735_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 339.0
WLSH2_k127_10886735_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002213 281.0
WLSH2_k127_10886735_5 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000007215 229.0
WLSH2_k127_10886735_6 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000009521 222.0
WLSH2_k127_10886735_7 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000006803 191.0
WLSH2_k127_10886735_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000008748 189.0
WLSH2_k127_10886735_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000001583 175.0
WLSH2_k127_10924406_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.569e-313 977.0
WLSH2_k127_10924406_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 459.0
WLSH2_k127_10924406_10 protein trimerization - - - 0.000000000000000000000000000000002028 150.0
WLSH2_k127_10924406_11 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000007541 133.0
WLSH2_k127_10924406_12 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000001538 89.0
WLSH2_k127_10924406_13 positive regulation of macromolecule biosynthetic process K03973 - - 0.0000000000001412 73.0
WLSH2_k127_10924406_14 MotA TolQ ExbB proton channel family K03561 - - 0.000000000002834 76.0
WLSH2_k127_10924406_15 - - - - 0.000000001074 62.0
WLSH2_k127_10924406_16 Winged helix-turn-helix domain (DUF2582) - - - 0.00000003771 58.0
WLSH2_k127_10924406_17 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000006329 65.0
WLSH2_k127_10924406_18 DNA excision K02806 - - 0.0001124 46.0
WLSH2_k127_10924406_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 419.0
WLSH2_k127_10924406_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 336.0
WLSH2_k127_10924406_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 292.0
WLSH2_k127_10924406_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000006771 221.0
WLSH2_k127_10924406_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000007793 216.0
WLSH2_k127_10924406_7 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000001198 196.0
WLSH2_k127_10924406_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000001107 174.0
WLSH2_k127_10924406_9 Type II and III secretion system protein K02507,K02666 - - 0.000000000000000000000000000000000001659 156.0
WLSH2_k127_10937213_0 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003755 267.0
WLSH2_k127_10976291_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 355.0
WLSH2_k127_10976291_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 304.0
WLSH2_k127_10976291_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000003408 91.0
WLSH2_k127_10976291_2 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000003419 222.0
WLSH2_k127_10976291_3 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000009432 223.0
WLSH2_k127_10976291_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000001249 211.0
WLSH2_k127_10976291_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000009361 178.0
WLSH2_k127_10976291_6 MOSC domain - - - 0.00000000000000000000000000000000000003529 151.0
WLSH2_k127_10976291_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000002204 145.0
WLSH2_k127_10976291_8 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000000000002019 138.0
WLSH2_k127_10976291_9 CS domain K13993 - - 0.00000000000000000000009138 106.0
WLSH2_k127_11133003_0 L-glutamate biosynthetic process K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 1.139e-274 863.0
WLSH2_k127_11133003_1 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000000000000000000000000000000000000002337 232.0
WLSH2_k127_11133003_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000144 204.0
WLSH2_k127_11185984_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 535.0
WLSH2_k127_11185984_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 485.0
WLSH2_k127_11185984_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000003474 218.0
WLSH2_k127_11185984_11 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000006406 213.0
WLSH2_k127_11185984_12 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000001228 186.0
WLSH2_k127_11185984_13 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000000000005475 183.0
WLSH2_k127_11185984_14 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000006253 178.0
WLSH2_k127_11185984_15 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000002406 174.0
WLSH2_k127_11185984_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000002284 164.0
WLSH2_k127_11185984_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000144 153.0
WLSH2_k127_11185984_18 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001154 146.0
WLSH2_k127_11185984_19 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000002521 132.0
WLSH2_k127_11185984_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 487.0
WLSH2_k127_11185984_20 Ribosomal protein L17 K02879,K16193 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000004595 102.0
WLSH2_k127_11185984_21 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000009623 99.0
WLSH2_k127_11185984_22 e3 binding domain K00658 - 2.3.1.61 0.000000000000001057 79.0
WLSH2_k127_11185984_23 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000001514 63.0
WLSH2_k127_11185984_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 426.0
WLSH2_k127_11185984_4 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 387.0
WLSH2_k127_11185984_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 328.0
WLSH2_k127_11185984_6 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 329.0
WLSH2_k127_11185984_7 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004666 279.0
WLSH2_k127_11185984_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008271 274.0
WLSH2_k127_11185984_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003461 258.0
WLSH2_k127_11217068_0 Belongs to the ClpA ClpB family K03696 - - 1.123e-232 732.0
WLSH2_k127_11217068_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 7.866e-222 697.0
WLSH2_k127_11217068_10 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 324.0
WLSH2_k127_11217068_11 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 304.0
WLSH2_k127_11217068_12 binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002829 277.0
WLSH2_k127_11217068_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000005527 260.0
WLSH2_k127_11217068_14 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000003453 239.0
WLSH2_k127_11217068_15 Thiamine biosynthesis protein ThiF K03148 - 2.7.7.73 0.00000000000000000000000000000000000000000000000000000000000000001228 229.0
WLSH2_k127_11217068_16 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000001445 211.0
WLSH2_k127_11217068_17 PFAM Oligosaccharyl transferase STT3 subunit K07151,K21306 - 2.4.99.18,2.4.99.21 0.0000000000000000000000000000000000000000003703 181.0
WLSH2_k127_11217068_18 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.00000000000000000000000000000000000217 146.0
WLSH2_k127_11217068_19 UvrB/uvrC motif K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - 0.000000000000000000000000000000000008802 143.0
WLSH2_k127_11217068_2 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 2.572e-209 657.0
WLSH2_k127_11217068_20 Yqey-like protein K09117 - - 0.00000000000000000000000000004621 122.0
WLSH2_k127_11217068_21 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000000000003247 121.0
WLSH2_k127_11217068_22 S-adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.0000000000000000000000000003399 119.0
WLSH2_k127_11217068_23 Evidence 5 No homology to any previously reported sequences K09005 - - 0.00000000000000000004038 96.0
WLSH2_k127_11217068_24 thiamine diphosphate biosynthetic process K03154 - - 0.00000000000004698 74.0
WLSH2_k127_11217068_3 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 534.0
WLSH2_k127_11217068_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 518.0
WLSH2_k127_11217068_5 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 490.0
WLSH2_k127_11217068_6 biosynthesis protein ThiH K03150 - 4.1.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 387.0
WLSH2_k127_11217068_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 372.0
WLSH2_k127_11217068_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 352.0
WLSH2_k127_11217068_9 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 350.0
WLSH2_k127_11328310_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 515.0
WLSH2_k127_11328310_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 480.0
WLSH2_k127_11328310_2 - - - - 0.000000000000000000000006379 103.0
WLSH2_k127_11328310_3 - - - - 0.0000000000000000000001675 99.0
WLSH2_k127_11328310_4 - - - - 0.000000000000002002 76.0
WLSH2_k127_11328310_6 - - - - 0.0000000005694 61.0
WLSH2_k127_11328310_7 - - - - 0.00000004551 55.0
WLSH2_k127_11382450_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 304.0
WLSH2_k127_11382450_1 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000003084 223.0
WLSH2_k127_11382450_2 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000001184 231.0
WLSH2_k127_11382450_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000003112 216.0
WLSH2_k127_11382450_4 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000002109 172.0
WLSH2_k127_11382450_5 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000002003 143.0
WLSH2_k127_11382450_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000001983 119.0
WLSH2_k127_11382450_7 BioY family K02014,K03523 - - 0.0000000000000000000000000009476 119.0
WLSH2_k127_11382450_8 PFAM CBS domain K07182 - - 0.00000000000000000001018 97.0
WLSH2_k127_11474053_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 398.0
WLSH2_k127_11474053_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 387.0
WLSH2_k127_11474053_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 368.0
WLSH2_k127_11474053_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 339.0
WLSH2_k127_11474053_4 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 306.0
WLSH2_k127_11474053_5 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000004162 259.0
WLSH2_k127_11474053_6 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000287 190.0
WLSH2_k127_11474053_7 Belongs to the MurCDEF family. MurE subfamily K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000002095 174.0
WLSH2_k127_11474053_8 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000002534 184.0
WLSH2_k127_11474053_9 Peptidase MA superfamily - - - 0.000000003596 67.0
WLSH2_k127_1359226_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 595.0
WLSH2_k127_1359226_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 400.0
WLSH2_k127_1359226_10 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0003288 48.0
WLSH2_k127_1359226_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 346.0
WLSH2_k127_1359226_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000001659 201.0
WLSH2_k127_1359226_4 - - - - 0.000000000000000000000000000000000000000007217 156.0
WLSH2_k127_1359226_5 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000226 143.0
WLSH2_k127_1359226_6 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000006994 80.0
WLSH2_k127_1359226_7 acr, cog1399 K07040 - - 0.0000000000001712 76.0
WLSH2_k127_1359226_9 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00004545 51.0
WLSH2_k127_1499166_0 Amylo-alpha-1,6-glucosidase - - - 0.000000000000000000000000000000000000000000000000000000001677 231.0
WLSH2_k127_1711338_0 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.00000001577 66.0
WLSH2_k127_1714606_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 309.0
WLSH2_k127_1714606_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001383 263.0
WLSH2_k127_1714606_10 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000005085 214.0
WLSH2_k127_1714606_11 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.000000000000000000000000000000000001697 152.0
WLSH2_k127_1714606_12 Transposase IS200 like K07491 - - 0.000000000000000000000000169 121.0
WLSH2_k127_1714606_13 Methyltransferase domain - - - 0.0000000000000000000000004412 113.0
WLSH2_k127_1714606_14 Glycosyl transferase, group 1 - - - 0.0000000000000000001706 100.0
WLSH2_k127_1714606_15 UbiE COQ5 methyltransferase - - - 0.00000000000000000107 94.0
WLSH2_k127_1714606_16 Methyltransferase type 11 - - - 0.00000002536 60.0
WLSH2_k127_1714606_17 Methyltransferase domain - - - 0.0000001418 61.0
WLSH2_k127_1714606_3 LmbE homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000005666 237.0
WLSH2_k127_1714606_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001665 244.0
WLSH2_k127_1714606_5 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000002435 244.0
WLSH2_k127_1714606_6 Type II secretory pathway component ExeA - - - 0.00000000000000000000000000000000000000000000000000000000000000001738 233.0
WLSH2_k127_1714606_7 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000000000009518 222.0
WLSH2_k127_1714606_8 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.000000000000000000000000000000000000000000000000000000000001986 222.0
WLSH2_k127_1714606_9 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000002361 216.0
WLSH2_k127_182060_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 533.0
WLSH2_k127_182060_1 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 328.0
WLSH2_k127_182060_2 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 317.0
WLSH2_k127_182060_3 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000001079 245.0
WLSH2_k127_182060_4 AAA domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000227 211.0
WLSH2_k127_1954069_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.129e-235 740.0
WLSH2_k127_1954069_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 7.77e-235 738.0
WLSH2_k127_1954069_10 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 370.0
WLSH2_k127_1954069_11 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 343.0
WLSH2_k127_1954069_12 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 313.0
WLSH2_k127_1954069_13 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 314.0
WLSH2_k127_1954069_14 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 315.0
WLSH2_k127_1954069_15 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 300.0
WLSH2_k127_1954069_16 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02236,K02278,K02506,K02654,K10966 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000005375 248.0
WLSH2_k127_1954069_17 TIGRFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000001603 258.0
WLSH2_k127_1954069_18 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000008752 233.0
WLSH2_k127_1954069_19 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000006612 192.0
WLSH2_k127_1954069_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 609.0
WLSH2_k127_1954069_20 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000002261 185.0
WLSH2_k127_1954069_21 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000005546 184.0
WLSH2_k127_1954069_22 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000001708 150.0
WLSH2_k127_1954069_23 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000001952 146.0
WLSH2_k127_1954069_24 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000312 142.0
WLSH2_k127_1954069_25 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02768,K02806 - 2.7.1.202 0.000000000000000000000000000000000005281 141.0
WLSH2_k127_1954069_26 phosphocarrier protein HPr K11189 - - 0.0000000000000000003835 89.0
WLSH2_k127_1954069_27 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000006756 61.0
WLSH2_k127_1954069_28 Phosphorylase superfamily - - - 0.00000322 57.0
WLSH2_k127_1954069_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 562.0
WLSH2_k127_1954069_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 551.0
WLSH2_k127_1954069_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 536.0
WLSH2_k127_1954069_6 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 473.0
WLSH2_k127_1954069_7 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 466.0
WLSH2_k127_1954069_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 442.0
WLSH2_k127_1954069_9 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 418.0
WLSH2_k127_2017283_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003966 243.0
WLSH2_k127_2017283_1 - - - - 0.000000000000000005371 95.0
WLSH2_k127_2017283_2 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000005624 61.0
WLSH2_k127_2017283_3 signal peptide processing K13280 - 3.4.21.89 0.0000005062 57.0
WLSH2_k127_2017283_4 Tetratricopeptide repeat - - - 0.00001389 54.0
WLSH2_k127_2017283_5 Putative zinc- or iron-chelating domain - - - 0.00004644 54.0
WLSH2_k127_202297_0 transferase activity, transferring glycosyl groups K00694,K20541 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016020,GO:0016051,GO:0030243,GO:0030244,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:0090540,GO:1901576 2.4.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 482.0
WLSH2_k127_202297_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 336.0
WLSH2_k127_202297_10 - - - - 0.00001303 50.0
WLSH2_k127_202297_11 Tetratricopeptide repeat - - - 0.0003316 52.0
WLSH2_k127_202297_2 Belongs to the glycosyl hydrolase 8 (cellulase D) family K00694,K15531,K20542 - 2.4.1.12,3.2.1.156,3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001639 291.0
WLSH2_k127_202297_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000004628 258.0
WLSH2_k127_202297_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000003521 243.0
WLSH2_k127_202297_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000002326 161.0
WLSH2_k127_202297_6 lycopene cyclase - - - 0.00000000000000006401 85.0
WLSH2_k127_202297_7 lycopene cyclase - - - 0.0000000000001772 76.0
WLSH2_k127_202297_8 Glycosyl transferase family group 2 - - - 0.000000000584 70.0
WLSH2_k127_202297_9 protein secretion K03116 - - 0.000000004474 59.0
WLSH2_k127_2028796_0 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 325.0
WLSH2_k127_2028796_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000004128 125.0
WLSH2_k127_2049186_0 PFAM Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 422.0
WLSH2_k127_2049186_1 Radical SAM superfamily K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 297.0
WLSH2_k127_2049186_2 Radical SAM superfamily K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007798 294.0
WLSH2_k127_2049186_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000246 253.0
WLSH2_k127_2049186_4 - - - - 0.0000000000000000000000000000000000000008481 166.0
WLSH2_k127_2049186_5 Psort location Cytoplasmic, score - - - 0.00000000000000000000429 97.0
WLSH2_k127_2158957_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 606.0
WLSH2_k127_2158957_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 397.0
WLSH2_k127_2158957_10 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000109 135.0
WLSH2_k127_2158957_11 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000005464 121.0
WLSH2_k127_2158957_12 PFAM CHAD domain containing protein - - - 0.000000000000000000000003937 113.0
WLSH2_k127_2158957_13 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000001332 93.0
WLSH2_k127_2158957_14 biogenesis protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000008496 88.0
WLSH2_k127_2158957_15 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000549 73.0
WLSH2_k127_2158957_16 Protein of unknown function (DUF1318) K09978 - - 0.000000003924 65.0
WLSH2_k127_2158957_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001713 253.0
WLSH2_k127_2158957_3 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000002081 237.0
WLSH2_k127_2158957_4 Psort location Cytoplasmic, score 9.97 K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000007038 225.0
WLSH2_k127_2158957_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000001337 228.0
WLSH2_k127_2158957_6 PP-loop family K14058 - - 0.0000000000000000000000000000000000000000000000000000000006032 211.0
WLSH2_k127_2158957_7 endonuclease III K03653 - 4.2.99.18 0.0000000000000000000000000000000000000000000000007175 182.0
WLSH2_k127_2158957_8 diguanylate cyclase - - - 0.00000000000000000000000000000000000001621 162.0
WLSH2_k127_2158957_9 beta-galactosidase activity - - - 0.00000000000000000000000000000000001253 153.0
WLSH2_k127_2160013_0 Alternative locus ID K00705 - 2.4.1.25 0.00000000000000002898 98.0
WLSH2_k127_2274216_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 370.0
WLSH2_k127_2274216_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 341.0
WLSH2_k127_2274216_10 Maf-like protein K06287 - - 0.0000000000000000000000000000000000001889 158.0
WLSH2_k127_2274216_11 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000001352 151.0
WLSH2_k127_2274216_12 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000001339 143.0
WLSH2_k127_2274216_13 Cold-shock protein K03704 - - 0.0000000000000000000000006362 105.0
WLSH2_k127_2274216_14 Pfam Response regulator receiver - - - 0.000000000000004839 80.0
WLSH2_k127_2274216_15 Belongs to the UPF0235 family K09131 - - 0.00000003327 58.0
WLSH2_k127_2274216_16 TM2 domain - - - 0.0000003193 56.0
WLSH2_k127_2274216_17 PFAM NADPH-dependent FMN reductase - - - 0.0004784 51.0
WLSH2_k127_2274216_2 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000424 284.0
WLSH2_k127_2274216_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002194 291.0
WLSH2_k127_2274216_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 259.0
WLSH2_k127_2274216_5 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000001083 261.0
WLSH2_k127_2274216_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000001541 239.0
WLSH2_k127_2274216_7 Conserved protein K01163 - - 0.00000000000000000000000000000000000000000000000000000001034 211.0
WLSH2_k127_2274216_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000001414 169.0
WLSH2_k127_2274216_9 Zn-dependent protease contains TPR repeats - - - 0.00000000000000000000000000000000000005741 160.0
WLSH2_k127_2430241_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1163.0
WLSH2_k127_2430241_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 1.948e-212 671.0
WLSH2_k127_2430241_10 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 501.0
WLSH2_k127_2430241_11 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 467.0
WLSH2_k127_2430241_12 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 453.0
WLSH2_k127_2430241_13 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 377.0
WLSH2_k127_2430241_14 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 358.0
WLSH2_k127_2430241_15 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 324.0
WLSH2_k127_2430241_16 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 318.0
WLSH2_k127_2430241_17 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 301.0
WLSH2_k127_2430241_18 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 288.0
WLSH2_k127_2430241_19 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001941 286.0
WLSH2_k127_2430241_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 3.304e-209 659.0
WLSH2_k127_2430241_20 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006884 289.0
WLSH2_k127_2430241_21 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000111 280.0
WLSH2_k127_2430241_22 PFAM Bacterial protein of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002666 269.0
WLSH2_k127_2430241_23 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004587 246.0
WLSH2_k127_2430241_24 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000105 235.0
WLSH2_k127_2430241_25 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000001337 214.0
WLSH2_k127_2430241_26 ABC transporter, ATP-binding protein K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000003321 213.0
WLSH2_k127_2430241_27 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000699 210.0
WLSH2_k127_2430241_28 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000001173 204.0
WLSH2_k127_2430241_29 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000007267 199.0
WLSH2_k127_2430241_3 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 608.0
WLSH2_k127_2430241_30 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000001813 184.0
WLSH2_k127_2430241_31 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000005219 178.0
WLSH2_k127_2430241_32 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000002812 169.0
WLSH2_k127_2430241_33 helix_turn _helix lactose operon repressor K02525,K02529 - - 0.0000000000000000000000000000000000000001807 160.0
WLSH2_k127_2430241_34 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000009557 159.0
WLSH2_k127_2430241_35 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000003531 141.0
WLSH2_k127_2430241_36 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000008971 132.0
WLSH2_k127_2430241_37 IMG reference gene - - - 0.00000000000000000000000000002111 136.0
WLSH2_k127_2430241_38 chlorophyll binding K03640 - - 0.0000000000000007913 89.0
WLSH2_k127_2430241_39 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000001895 78.0
WLSH2_k127_2430241_4 Dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 584.0
WLSH2_k127_2430241_40 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000001242 78.0
WLSH2_k127_2430241_41 Putative peptidoglycan binding domain - - - 0.00000000007646 70.0
WLSH2_k127_2430241_42 Produces ATP from ADP in the presence of a proton gradient across the membrane K02113,K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000001067 67.0
WLSH2_k127_2430241_43 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.000000002269 68.0
WLSH2_k127_2430241_44 ATP synthase B/B' CF(0) K02109 - - 0.00001247 53.0
WLSH2_k127_2430241_45 PFAM Preprotein translocase SecG subunit K03075 - - 0.00002172 53.0
WLSH2_k127_2430241_5 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 570.0
WLSH2_k127_2430241_6 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 561.0
WLSH2_k127_2430241_7 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 538.0
WLSH2_k127_2430241_8 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 530.0
WLSH2_k127_2430241_9 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 519.0
WLSH2_k127_2509017_0 type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 526.0
WLSH2_k127_2509017_1 General secretory system II protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 524.0
WLSH2_k127_2509017_2 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 370.0
WLSH2_k127_2509017_3 response - - - 0.00000000000000000000000000000000000000000000000000001674 202.0
WLSH2_k127_2509017_4 General secretory system II protein E domain protein K02652 - - 0.0000000000000000000000000002584 119.0
WLSH2_k127_2509017_5 diguanylate cyclase - - - 0.000000000001366 80.0
WLSH2_k127_2665913_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.483e-270 856.0
WLSH2_k127_2665913_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 485.0
WLSH2_k127_2712864_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.843e-300 947.0
WLSH2_k127_2712864_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.389e-194 621.0
WLSH2_k127_2712864_10 Patatin-like phospholipase K01999,K07001 - - 0.00000000000000000000000000000000000000000000000000000001542 221.0
WLSH2_k127_2712864_11 CDP-glucose 4,6-dehydratase K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000002529 203.0
WLSH2_k127_2712864_12 DoxX K15977 - - 0.00000000000000000000000000000000009752 137.0
WLSH2_k127_2712864_13 diguanylate cyclase - - - 0.0000000000000000000001867 102.0
WLSH2_k127_2712864_14 phosphopantothenoylcysteine decarboxylase activity K01598,K13038,K21977 - 4.1.1.36,6.3.2.5 0.00000000000000000004897 98.0
WLSH2_k127_2712864_15 - - - - 0.0000003356 57.0
WLSH2_k127_2712864_16 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0004857 43.0
WLSH2_k127_2712864_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 460.0
WLSH2_k127_2712864_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 459.0
WLSH2_k127_2712864_4 Carbon starvation protein K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 446.0
WLSH2_k127_2712864_5 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 420.0
WLSH2_k127_2712864_6 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 385.0
WLSH2_k127_2712864_7 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 340.0
WLSH2_k127_2712864_8 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000002577 233.0
WLSH2_k127_2712864_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000002602 230.0
WLSH2_k127_2729557_0 PFAM ferredoxin-dependent glutamate synthase - - - 1.616e-279 867.0
WLSH2_k127_2729557_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000007573 226.0
WLSH2_k127_2729557_2 OmpA family - - - 0.0000000000000000000000000000005517 130.0
WLSH2_k127_2902798_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1020.0
WLSH2_k127_2902798_1 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007528 563.0
WLSH2_k127_2903171_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 594.0
WLSH2_k127_2903171_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 523.0
WLSH2_k127_2903171_2 type II secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006538 260.0
WLSH2_k127_2903171_4 Membrane K08981 - - 0.00000479 55.0
WLSH2_k127_296513_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.971e-202 646.0
WLSH2_k127_296513_1 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 452.0
WLSH2_k127_296513_2 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 323.0
WLSH2_k127_296513_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001141 266.0
WLSH2_k127_296513_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000007175 255.0
WLSH2_k127_296513_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.0000000000000000000000000000000000000000000000000000004178 202.0
WLSH2_k127_296513_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000002328 193.0
WLSH2_k127_296513_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000002507 98.0
WLSH2_k127_3033548_0 AcrB/AcrD/AcrF family K03296 - - 3.235e-238 772.0
WLSH2_k127_3033548_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.422e-226 721.0
WLSH2_k127_3033548_10 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000003672 216.0
WLSH2_k127_3033548_11 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000001296 212.0
WLSH2_k127_3033548_12 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000003845 210.0
WLSH2_k127_3033548_13 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000009287 210.0
WLSH2_k127_3033548_14 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000001959 180.0
WLSH2_k127_3033548_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000002494 149.0
WLSH2_k127_3033548_16 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000004871 139.0
WLSH2_k127_3033548_17 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000002855 136.0
WLSH2_k127_3033548_18 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000007629 140.0
WLSH2_k127_3033548_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000001439 136.0
WLSH2_k127_3033548_2 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 546.0
WLSH2_k127_3033548_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000000321 128.0
WLSH2_k127_3033548_21 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000003437 127.0
WLSH2_k127_3033548_22 outer membrane efflux protein - - - 0.00000000000000000000000005001 122.0
WLSH2_k127_3033548_23 phosphatidylglycerophosphatase activity K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.0000000000000000000000002512 111.0
WLSH2_k127_3033548_24 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000006441 101.0
WLSH2_k127_3033548_25 Secretion system protein K12276 - - 0.00000000000000000000007712 106.0
WLSH2_k127_3033548_26 cheY-homologous receiver domain K02490 - - 0.0000000000000000000764 93.0
WLSH2_k127_3033548_27 Helix-turn-helix domain - - - 0.000000000000000000433 99.0
WLSH2_k127_3033548_28 Type II IV secretion system protein K02454,K02652 - - 0.00000000000000000119 91.0
WLSH2_k127_3033548_29 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000001029 85.0
WLSH2_k127_3033548_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 527.0
WLSH2_k127_3033548_30 - - - - 0.000000000002846 72.0
WLSH2_k127_3033548_31 Rubrerythrin - - - 0.00000003252 56.0
WLSH2_k127_3033548_32 Membrane transport protein K07088 - - 0.00001459 56.0
WLSH2_k127_3033548_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 338.0
WLSH2_k127_3033548_5 Uncharacterized protein family UPF0004 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 324.0
WLSH2_k127_3033548_6 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002756 267.0
WLSH2_k127_3033548_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000764 275.0
WLSH2_k127_3033548_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000001189 243.0
WLSH2_k127_3033548_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000007875 237.0
WLSH2_k127_3129784_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 588.0
WLSH2_k127_3129784_1 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001538 286.0
WLSH2_k127_3129784_2 PFAM binding-protein-dependent transport systems inner membrane component K02026,K10119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002386 284.0
WLSH2_k127_3129784_3 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002293 273.0
WLSH2_k127_3129784_4 Type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000002899 238.0
WLSH2_k127_3129784_5 type II and III secretion system protein K02507,K02666 - - 0.0000000000000000000000000000000000000000003332 174.0
WLSH2_k127_3129784_6 cell wall anchor domain - - - 0.00000002464 67.0
WLSH2_k127_3129784_7 Pfam:N_methyl_2 - - - 0.0000001945 58.0
WLSH2_k127_3129784_8 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00002562 57.0
WLSH2_k127_3129784_9 Pilus assembly protein PilX - - - 0.0008835 51.0
WLSH2_k127_3156374_0 PFAM fumarate lyase K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 580.0
WLSH2_k127_3156374_1 TIGRFAM Small GTP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 526.0
WLSH2_k127_3156374_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000004164 216.0
WLSH2_k127_3156374_3 Thioredoxin K03671 - - 0.000000000000000000000000000000000002553 141.0
WLSH2_k127_3156374_4 - - - - 0.0000000000000000001644 105.0
WLSH2_k127_3156374_5 - - - - 0.000000000000000006593 98.0
WLSH2_k127_3330573_0 PKD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 492.0
WLSH2_k127_3330573_1 Belongs to the DEAD box helicase family K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 463.0
WLSH2_k127_3330573_10 Peptidase S24-like K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000002045 214.0
WLSH2_k127_3330573_11 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000001019 201.0
WLSH2_k127_3330573_12 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000001518 187.0
WLSH2_k127_3330573_13 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000002633 169.0
WLSH2_k127_3330573_14 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000001361 168.0
WLSH2_k127_3330573_15 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000002058 167.0
WLSH2_k127_3330573_16 Psort location CytoplasmicMembrane, score 10.00 K07052 - - 0.00000000000000000000000000000000000000002349 160.0
WLSH2_k127_3330573_17 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000604 163.0
WLSH2_k127_3330573_18 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000001565 151.0
WLSH2_k127_3330573_19 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000004492 138.0
WLSH2_k127_3330573_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 401.0
WLSH2_k127_3330573_20 Cupin domain - - - 0.000000000000000000000000000000001046 132.0
WLSH2_k127_3330573_21 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000007491 133.0
WLSH2_k127_3330573_22 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000000005043 117.0
WLSH2_k127_3330573_23 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000009828 115.0
WLSH2_k127_3330573_24 AsmA-like C-terminal region K07289 - - 0.00000000007096 76.0
WLSH2_k127_3330573_25 UbiA prenyltransferase family K03179,K04040,K17105 - 2.5.1.133,2.5.1.39,2.5.1.42,2.5.1.62 0.0000000479 66.0
WLSH2_k127_3330573_3 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 338.0
WLSH2_k127_3330573_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 293.0
WLSH2_k127_3330573_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 294.0
WLSH2_k127_3330573_6 TIGRFAM hydro-lyases, Fe-S type, tartrate fumarate subfamily, alpha region K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002215 279.0
WLSH2_k127_3330573_7 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000003002 252.0
WLSH2_k127_3330573_8 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000008143 248.0
WLSH2_k127_3330573_9 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000006229 216.0
WLSH2_k127_3444790_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.852e-203 650.0
WLSH2_k127_3444790_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 400.0
WLSH2_k127_3444790_2 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 387.0
WLSH2_k127_3444790_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 359.0
WLSH2_k127_3444790_4 thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 325.0
WLSH2_k127_3444790_5 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00177 - 1.2.7.3 0.000000000000000000000000000000000000003845 152.0
WLSH2_k127_3444790_6 PFAM 4Fe-4S K00176 - 1.2.7.3 0.000000000000000000666 87.0
WLSH2_k127_3444790_7 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.0000000000000326 74.0
WLSH2_k127_3444790_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000005378 67.0
WLSH2_k127_3444790_9 twitching motility protein K02669 - - 0.0007678 48.0
WLSH2_k127_3588371_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 4.997e-266 830.0
WLSH2_k127_3588371_1 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 457.0
WLSH2_k127_3588371_10 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004859 249.0
WLSH2_k127_3588371_11 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003063 238.0
WLSH2_k127_3588371_12 Acyl-homoserine-lactone synthase - - - 0.000000000000000000000000000000000000000000000000002058 191.0
WLSH2_k127_3588371_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.00000000000000000000000000000000000000000000000003178 183.0
WLSH2_k127_3588371_14 Histidine kinase - - - 0.0000000000000000000000000000000000000000008087 172.0
WLSH2_k127_3588371_15 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000007838 165.0
WLSH2_k127_3588371_16 Polysaccharide deacetylase K11931 - - 0.000000000000000000000000000219 125.0
WLSH2_k127_3588371_17 PEP-CTERM motif - - - 0.00000000000000000000153 96.0
WLSH2_k127_3588371_18 spore cortex-lytic enzyme K01449 GO:0005575,GO:0005623,GO:0042763,GO:0044464 3.5.1.28 0.0000000001738 67.0
WLSH2_k127_3588371_19 Carboxypeptidase K01308 - 3.4.19.11 0.0000000002229 68.0
WLSH2_k127_3588371_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 467.0
WLSH2_k127_3588371_20 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000006118 65.0
WLSH2_k127_3588371_21 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.0000000009636 63.0
WLSH2_k127_3588371_23 Protein of unknown function (DUF3485) - - - 0.00000004502 62.0
WLSH2_k127_3588371_24 Sensory domain found in PocR - - - 0.000001597 60.0
WLSH2_k127_3588371_25 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.00001182 53.0
WLSH2_k127_3588371_26 - - - - 0.00009016 44.0
WLSH2_k127_3588371_27 protein trimerization K08309 - - 0.0001128 53.0
WLSH2_k127_3588371_3 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 428.0
WLSH2_k127_3588371_4 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 391.0
WLSH2_k127_3588371_5 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 336.0
WLSH2_k127_3588371_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 295.0
WLSH2_k127_3588371_7 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001893 267.0
WLSH2_k127_3588371_8 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007205 246.0
WLSH2_k127_3588371_9 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002286 249.0
WLSH2_k127_3856689_0 PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 525.0
WLSH2_k127_3856689_1 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 402.0
WLSH2_k127_3856689_2 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 316.0
WLSH2_k127_3856689_3 tRNA processing - - - 0.000000000000000000000000000000000001471 151.0
WLSH2_k127_3983878_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 7.357e-209 669.0
WLSH2_k127_3983878_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 311.0
WLSH2_k127_3983878_2 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002038 269.0
WLSH2_k127_3983878_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000001698 166.0
WLSH2_k127_3985085_0 Glycosyltransferase 36 associated - - - 2.919e-271 871.0
WLSH2_k127_3985085_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 584.0
WLSH2_k127_3985085_10 Flagellar motor protein K02557 - - 0.00000000000000000004118 99.0
WLSH2_k127_3985085_11 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000003855 91.0
WLSH2_k127_3985085_13 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000000006788 81.0
WLSH2_k127_3985085_14 - - - - 0.00000000000003687 78.0
WLSH2_k127_3985085_15 Putative zinc- or iron-chelating domain - - - 0.00002136 52.0
WLSH2_k127_3985085_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0007219 50.0
WLSH2_k127_3985085_2 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 310.0
WLSH2_k127_3985085_3 PFAM metal-dependent phosphohydrolase, HD sub domain K02103,K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005989 277.0
WLSH2_k127_3985085_4 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000003824 205.0
WLSH2_k127_3985085_5 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000001279 184.0
WLSH2_k127_3985085_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000001739 157.0
WLSH2_k127_3985085_7 molybdenum cofactor - - - 0.0000000000000000000000000000000000003113 146.0
WLSH2_k127_3985085_8 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000001662 125.0
WLSH2_k127_3985085_9 - - - - 0.000000000000000000001223 104.0
WLSH2_k127_4110486_0 NADH dehydrogenase - - - 7.845e-251 786.0
WLSH2_k127_4110486_1 iron-sulfur cluster assembly K00336,K18332 - 1.12.1.3,1.6.5.3 3.035e-198 636.0
WLSH2_k127_4110486_10 ATPases associated with a variety of cellular activities K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 301.0
WLSH2_k127_4110486_11 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 295.0
WLSH2_k127_4110486_12 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 287.0
WLSH2_k127_4110486_13 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007143 282.0
WLSH2_k127_4110486_14 PFAM periplasmic solute binding protein K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001445 283.0
WLSH2_k127_4110486_15 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000000000000006156 226.0
WLSH2_k127_4110486_16 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000002895 212.0
WLSH2_k127_4110486_17 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000002734 214.0
WLSH2_k127_4110486_18 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000913 195.0
WLSH2_k127_4110486_19 manganese ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000001526 182.0
WLSH2_k127_4110486_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 576.0
WLSH2_k127_4110486_20 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000000000003062 177.0
WLSH2_k127_4110486_21 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000004543 175.0
WLSH2_k127_4110486_22 Thioredoxin-like [2Fe-2S] ferredoxin - - - 0.000000000000000000000000000000000000000000000006248 177.0
WLSH2_k127_4110486_23 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000000000000001908 173.0
WLSH2_k127_4110486_24 Ferredoxin K00335,K17992 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000002075 158.0
WLSH2_k127_4110486_25 Ferric uptake regulator, Fur family K03711 - - 0.00000000000000000000000000000000002324 139.0
WLSH2_k127_4110486_26 cheY-homologous receiver domain K07658 - - 0.000000000000000000000000000000001192 133.0
WLSH2_k127_4110486_27 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000001564 117.0
WLSH2_k127_4110486_28 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000004165 109.0
WLSH2_k127_4110486_29 - - - - 0.00000000000000000008989 91.0
WLSH2_k127_4110486_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 581.0
WLSH2_k127_4110486_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 551.0
WLSH2_k127_4110486_5 Iron-only hydrogenase maturation rSAM protein HydG K03150 - 4.1.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 452.0
WLSH2_k127_4110486_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 373.0
WLSH2_k127_4110486_7 radical SAM domain protein K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 323.0
WLSH2_k127_4110486_8 ABC-3 protein K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 319.0
WLSH2_k127_4110486_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 331.0
WLSH2_k127_4148991_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 515.0
WLSH2_k127_4148991_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 430.0
WLSH2_k127_4148991_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000009654 145.0
WLSH2_k127_4148991_11 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000006328 127.0
WLSH2_k127_4148991_12 calcium ion homeostasis - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827 - 0.0000000000000000000003465 104.0
WLSH2_k127_4148991_13 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000001102 66.0
WLSH2_k127_4148991_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000001278 59.0
WLSH2_k127_4148991_16 pilus assembly protein K02662 - - 0.00002702 57.0
WLSH2_k127_4148991_17 proton-transporting ATP synthase activity, rotational mechanism K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0001531 49.0
WLSH2_k127_4148991_18 Type II secretion system (T2SS), protein K - - - 0.0005181 51.0
WLSH2_k127_4148991_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 407.0
WLSH2_k127_4148991_3 secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 331.0
WLSH2_k127_4148991_4 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 296.0
WLSH2_k127_4148991_5 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001949 269.0
WLSH2_k127_4148991_6 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000048 227.0
WLSH2_k127_4148991_7 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000001091 219.0
WLSH2_k127_4148991_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000008405 221.0
WLSH2_k127_4148991_9 FIST C domain - - - 0.0000000000000000000000000000000000007969 154.0
WLSH2_k127_4174382_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 531.0
WLSH2_k127_4174382_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 336.0
WLSH2_k127_4174382_2 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 340.0
WLSH2_k127_4174382_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000001336 209.0
WLSH2_k127_4174382_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000005301 182.0
WLSH2_k127_4174382_5 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000004632 147.0
WLSH2_k127_4174382_6 imidazoleglycerol-phosphate dehydratase K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.000000000000000000000000000006577 123.0
WLSH2_k127_4174382_7 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000003144 102.0
WLSH2_k127_4174382_8 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000003285 78.0
WLSH2_k127_4232891_0 type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 490.0
WLSH2_k127_4232891_1 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000769 82.0
WLSH2_k127_424222_0 A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 318.0
WLSH2_k127_424222_1 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000001604 227.0
WLSH2_k127_424222_2 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000103 214.0
WLSH2_k127_424222_3 Deoxyribonuclease K03424 - - 0.000000000000000000000000000000000000000008072 163.0
WLSH2_k127_424222_4 ThiF family K22132 - - 0.0000000000000000000000000000000000005831 143.0
WLSH2_k127_4349901_0 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 575.0
WLSH2_k127_4349901_1 neurotransmitter:sodium symporter activity K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 565.0
WLSH2_k127_4349901_10 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.000000000000000000000000000000000000000009163 161.0
WLSH2_k127_4349901_11 PFAM Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.00000000000000000000000000000000000000001273 166.0
WLSH2_k127_4349901_12 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000001222 161.0
WLSH2_k127_4349901_13 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K02849,K12982 - - 0.0000000000000000000000000000000000004932 160.0
WLSH2_k127_4349901_14 heptosyltransferase II K02843 - - 0.0000000000000000000000000001977 133.0
WLSH2_k127_4349901_15 Nuclease (SNase domain protein) K01174 - 3.1.31.1 0.00000000000000000000000001764 119.0
WLSH2_k127_4349901_16 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000002945 96.0
WLSH2_k127_4349901_17 COG1560 Lauroyl myristoyl acyltransferase K02517 - 2.3.1.241 0.00000000000000000004144 106.0
WLSH2_k127_4349901_18 Mitochondrial fission ELM1 K07276 - - 0.0000000001117 75.0
WLSH2_k127_4349901_19 auxin-activated signaling pathway K07088 - - 0.000002712 59.0
WLSH2_k127_4349901_2 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 438.0
WLSH2_k127_4349901_20 PFAM amino acid-binding ACT domain protein - - - 0.0004643 48.0
WLSH2_k127_4349901_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 301.0
WLSH2_k127_4349901_4 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000001841 243.0
WLSH2_k127_4349901_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000002016 209.0
WLSH2_k127_4349901_6 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000001293 203.0
WLSH2_k127_4349901_7 HD domain - - - 0.00000000000000000000000000000000000000000000000002668 196.0
WLSH2_k127_4349901_8 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000004496 167.0
WLSH2_k127_4349901_9 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000676 168.0
WLSH2_k127_4504596_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 1.225e-199 651.0
WLSH2_k127_4504596_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 452.0
WLSH2_k127_4504596_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007574 368.0
WLSH2_k127_4504596_3 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000001081 143.0
WLSH2_k127_4504596_4 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000007149 81.0
WLSH2_k127_4513865_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.256e-195 627.0
WLSH2_k127_4513865_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 590.0
WLSH2_k127_4513865_10 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000005867 246.0
WLSH2_k127_4513865_11 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000001315 240.0
WLSH2_k127_4513865_13 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000002605 179.0
WLSH2_k127_4513865_14 biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000000000953 158.0
WLSH2_k127_4513865_15 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000003266 162.0
WLSH2_k127_4513865_17 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000006442 135.0
WLSH2_k127_4513865_18 peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000002565 139.0
WLSH2_k127_4513865_19 PFAM HD domain - - - 0.0000000000000000000000000000004808 132.0
WLSH2_k127_4513865_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 541.0
WLSH2_k127_4513865_20 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000004278 107.0
WLSH2_k127_4513865_21 energy transducer activity K03646,K03832 - - 0.00000000005262 72.0
WLSH2_k127_4513865_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 345.0
WLSH2_k127_4513865_4 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 355.0
WLSH2_k127_4513865_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 334.0
WLSH2_k127_4513865_6 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 337.0
WLSH2_k127_4513865_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 308.0
WLSH2_k127_4513865_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002532 283.0
WLSH2_k127_4513865_9 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003186 264.0
WLSH2_k127_4545895_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 467.0
WLSH2_k127_4545895_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 455.0
WLSH2_k127_4545895_10 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000002796 65.0
WLSH2_k127_4545895_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00006222 50.0
WLSH2_k127_4545895_13 Psort location Cytoplasmic, score - - - 0.0002024 51.0
WLSH2_k127_4545895_14 Monoamine oxidase K00274 - 1.4.3.4 0.0002427 46.0
WLSH2_k127_4545895_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 315.0
WLSH2_k127_4545895_3 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000004406 243.0
WLSH2_k127_4545895_4 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000004866 223.0
WLSH2_k127_4545895_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000005814 193.0
WLSH2_k127_4545895_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000007812 161.0
WLSH2_k127_4545895_7 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000007213 134.0
WLSH2_k127_4545895_8 Class II aldolase K01628 - 4.1.2.17 0.000000000000000232 90.0
WLSH2_k127_4545895_9 Putative cyclase - - - 0.00000000000123 71.0
WLSH2_k127_4574588_0 - - - - 0.000000000000000000000000000000000000000000003265 190.0
WLSH2_k127_459631_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0001558 56.0
WLSH2_k127_4617149_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 357.0
WLSH2_k127_4617149_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 346.0
WLSH2_k127_4617149_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 304.0
WLSH2_k127_4617149_3 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 301.0
WLSH2_k127_4617149_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000001401 258.0
WLSH2_k127_4617149_5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000001342 161.0
WLSH2_k127_4643034_0 Glutamine synthetase, catalytic region K01915 - 6.3.1.2 8.191e-231 736.0
WLSH2_k127_4643034_1 Anticodon-binding domain of tRNA K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 541.0
WLSH2_k127_4643034_10 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002346 284.0
WLSH2_k127_4643034_11 Stage 0 sporulation protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001592 275.0
WLSH2_k127_4643034_12 PilT protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005442 269.0
WLSH2_k127_4643034_13 serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000002206 265.0
WLSH2_k127_4643034_14 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007633 263.0
WLSH2_k127_4643034_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000004207 252.0
WLSH2_k127_4643034_16 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000006778 222.0
WLSH2_k127_4643034_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000008736 232.0
WLSH2_k127_4643034_18 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000001452 214.0
WLSH2_k127_4643034_19 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000004609 208.0
WLSH2_k127_4643034_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 491.0
WLSH2_k127_4643034_20 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000001562 192.0
WLSH2_k127_4643034_21 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000008998 196.0
WLSH2_k127_4643034_22 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000001708 181.0
WLSH2_k127_4643034_23 Transcriptional regulator, AsnC family - - - 0.0000000000000000000000000000000000000000003343 162.0
WLSH2_k127_4643034_24 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000004283 160.0
WLSH2_k127_4643034_25 protein family UPF0079, ATPase K06925 - - 0.000000000000000000000000000000008121 133.0
WLSH2_k127_4643034_26 ComF family K02242 - - 0.000000000000000000000000005934 119.0
WLSH2_k127_4643034_27 PFAM Peptidase M22, glycoprotease K01409,K14742 - 2.3.1.234 0.000000000000000000000009068 111.0
WLSH2_k127_4643034_28 MlaD protein K02067 - - 0.000000000000000000003214 102.0
WLSH2_k127_4643034_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 461.0
WLSH2_k127_4643034_4 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 437.0
WLSH2_k127_4643034_5 glucose-1-phosphate adenylyltransferase K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 407.0
WLSH2_k127_4643034_6 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 384.0
WLSH2_k127_4643034_7 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 364.0
WLSH2_k127_4643034_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 335.0
WLSH2_k127_4643034_9 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 325.0
WLSH2_k127_4918581_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004616 287.0
WLSH2_k127_4918581_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000559 293.0
WLSH2_k127_4918581_2 Methyltransferase domain protein - - - 0.00000000000000000000006986 108.0
WLSH2_k127_4918581_3 Mycolic acid cyclopropane synthetase - - - 0.0000000000000002663 87.0
WLSH2_k127_4918581_4 Predicted membrane protein (DUF2079) K07778 - 2.7.13.3 0.000000001089 72.0
WLSH2_k127_4982414_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 8.037e-234 733.0
WLSH2_k127_4982414_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.054e-196 637.0
WLSH2_k127_4982414_10 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005661 278.0
WLSH2_k127_4982414_11 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009105 271.0
WLSH2_k127_4982414_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000001912 188.0
WLSH2_k127_4982414_13 Domain of unknown function (DUF4912) K09942 - - 0.0000000000000000000000000000000000000000000000006744 189.0
WLSH2_k127_4982414_14 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000001562 161.0
WLSH2_k127_4982414_15 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000275 141.0
WLSH2_k127_4982414_16 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000006403 132.0
WLSH2_k127_4982414_17 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000002162 100.0
WLSH2_k127_4982414_2 Type II IV secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 422.0
WLSH2_k127_4982414_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 421.0
WLSH2_k127_4982414_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 401.0
WLSH2_k127_4982414_5 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 387.0
WLSH2_k127_4982414_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 354.0
WLSH2_k127_4982414_7 Type II/IV secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 342.0
WLSH2_k127_4982414_8 NusA-like KH domain K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 336.0
WLSH2_k127_4982414_9 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 331.0
WLSH2_k127_4986481_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 7.386e-204 662.0
WLSH2_k127_4986481_1 CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 4.326e-201 649.0
WLSH2_k127_4986481_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000004115 110.0
WLSH2_k127_4986481_11 Belongs to the UPF0102 family K07460 - - 0.00000000000000000007335 93.0
WLSH2_k127_4986481_12 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000003298 99.0
WLSH2_k127_4986481_13 TPR repeat - - - 0.000000000001128 78.0
WLSH2_k127_4986481_14 Formiminotransferase-cyclodeaminase - - - 0.000000114 60.0
WLSH2_k127_4986481_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.54e-198 626.0
WLSH2_k127_4986481_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 519.0
WLSH2_k127_4986481_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 413.0
WLSH2_k127_4986481_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 363.0
WLSH2_k127_4986481_6 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 312.0
WLSH2_k127_4986481_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000003103 250.0
WLSH2_k127_4986481_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000001984 163.0
WLSH2_k127_4986481_9 Binds the 23S rRNA K02909 - - 0.00000000000000000000000008406 108.0
WLSH2_k127_5004078_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 593.0
WLSH2_k127_5004078_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 533.0
WLSH2_k127_5004078_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000007591 186.0
WLSH2_k127_5004078_11 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000001361 177.0
WLSH2_k127_5004078_12 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K00627,K01571,K02160 - 2.3.1.12,4.1.1.3 0.0000000000000000000000000000000000000309 150.0
WLSH2_k127_5004078_13 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000184 150.0
WLSH2_k127_5004078_14 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000107 97.0
WLSH2_k127_5004078_15 Alkaline-shock protein - - - 0.0000000000005094 74.0
WLSH2_k127_5004078_16 Domain of unknown function (DUF1844) - - - 0.00000000001357 69.0
WLSH2_k127_5004078_17 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000414 61.0
WLSH2_k127_5004078_18 Protein conserved in bacteria - - - 0.00000008066 61.0
WLSH2_k127_5004078_19 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0002323 46.0
WLSH2_k127_5004078_2 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 477.0
WLSH2_k127_5004078_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 289.0
WLSH2_k127_5004078_4 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002298 266.0
WLSH2_k127_5004078_5 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000000000000000000000001265 207.0
WLSH2_k127_5004078_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000001633 205.0
WLSH2_k127_5004078_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000001628 206.0
WLSH2_k127_5004078_8 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000004953 201.0
WLSH2_k127_5004078_9 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000004663 190.0
WLSH2_k127_5068935_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 4.953e-215 685.0
WLSH2_k127_5068935_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 592.0
WLSH2_k127_5068935_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001395 261.0
WLSH2_k127_5068935_3 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000313 207.0
WLSH2_k127_5068935_4 Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000629 184.0
WLSH2_k127_5068935_5 Phospholipid methyltransferase - - - 0.00000000000000000002639 99.0
WLSH2_k127_5068935_6 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000009453 63.0
WLSH2_k127_5068935_7 Prokaryotic N-terminal methylation motif - - - 0.00001093 54.0
WLSH2_k127_5083516_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 549.0
WLSH2_k127_5083516_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 507.0
WLSH2_k127_5083516_10 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000009305 197.0
WLSH2_k127_5083516_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000151 207.0
WLSH2_k127_5083516_12 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000000000000000000000000000000000006218 141.0
WLSH2_k127_5083516_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000001182 117.0
WLSH2_k127_5083516_14 Methionine biosynthesis protein MetW - - - 0.00000000000000000107 94.0
WLSH2_k127_5083516_15 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000001395 68.0
WLSH2_k127_5083516_16 - - - - 0.000000000018 65.0
WLSH2_k127_5083516_17 Peptide chain release factor - - - 0.0000001925 57.0
WLSH2_k127_5083516_19 COG3209 Rhs family protein - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0004549,GO:0006139,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016078,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - 0.000587 52.0
WLSH2_k127_5083516_2 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 458.0
WLSH2_k127_5083516_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01666 - 4.1.3.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 397.0
WLSH2_k127_5083516_4 NUBPL iron-transfer P-loop NTPase K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 350.0
WLSH2_k127_5083516_5 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 347.0
WLSH2_k127_5083516_6 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 314.0
WLSH2_k127_5083516_7 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001331 278.0
WLSH2_k127_5083516_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000001629 250.0
WLSH2_k127_5083516_9 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000002557 239.0
WLSH2_k127_5123630_0 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 469.0
WLSH2_k127_5123630_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000002154 266.0
WLSH2_k127_5123630_2 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.0000000000000000001782 89.0
WLSH2_k127_5228225_0 PFAM glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 600.0
WLSH2_k127_5228225_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 506.0
WLSH2_k127_5228225_2 Glycosyl transferase family 2 K11936,K14666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 390.0
WLSH2_k127_5228225_3 PFAM glycine cleavage T protein (aminomethyl transferase) K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 366.0
WLSH2_k127_5228225_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 317.0
WLSH2_k127_5228225_5 COGs COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000001204 224.0
WLSH2_k127_5228225_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000005133 157.0
WLSH2_k127_5228225_7 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000001618 163.0
WLSH2_k127_5228225_8 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.000000000000000218 89.0
WLSH2_k127_5228225_9 ThiF family K22132 - - 0.00000000000002526 75.0
WLSH2_k127_5547020_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 496.0
WLSH2_k127_5547020_1 Arsenical pump membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 386.0
WLSH2_k127_5547020_2 TonB-dependent receptor plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002968 262.0
WLSH2_k127_5547020_3 TIGRFAM TIGR00268 family protein K06864 - - 0.000000000000000000000000000000000000000000000000000000009254 209.0
WLSH2_k127_5547020_4 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000008884 171.0
WLSH2_k127_5547020_5 NifU-like domain - - - 0.0000000000000000000000003725 107.0
WLSH2_k127_5547020_6 Transcriptional regulator - - - 0.000000000000000000000004322 108.0
WLSH2_k127_5547020_7 - - - - 0.000000000000007913 76.0
WLSH2_k127_5547020_8 CAAX protease self-immunity K07052 - - 0.000001706 61.0
WLSH2_k127_5547020_9 YHS domain - - - 0.00003664 51.0
WLSH2_k127_5550172_0 flp pilus assembly protein K12510 - - 0.00000000000000000000000000000000000003915 154.0
WLSH2_k127_5550172_1 PFAM type II secretion system K12511 - - 0.000000000000000000000000000000002358 140.0
WLSH2_k127_5695932_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 3.39e-251 789.0
WLSH2_k127_5695932_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009553 477.0
WLSH2_k127_5695932_2 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 432.0
WLSH2_k127_5695932_3 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000114 191.0
WLSH2_k127_5695932_4 ATP synthase subunit C K02124 - - 0.0000000000000000000000000000000000000000000000000003201 188.0
WLSH2_k127_5695932_5 - - - - 0.0000000000000000000000000000000000000000000001547 176.0
WLSH2_k127_5695932_6 - - - - 0.0000000000000000000000000000000000000000000008536 175.0
WLSH2_k127_5695932_7 Ion channel - - - 0.0000000000000000000000000005049 122.0
WLSH2_k127_5695932_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000004755 98.0
WLSH2_k127_5695932_9 PFAM phosphate acetyl butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000005769 79.0
WLSH2_k127_5831363_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 375.0
WLSH2_k127_5831363_1 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000024 245.0
WLSH2_k127_5831363_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000002248 230.0
WLSH2_k127_5831363_3 metal cluster binding K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.000001045 50.0
WLSH2_k127_5831363_4 ATPases associated with a variety of cellular activities K01990 - - 0.00005272 48.0
WLSH2_k127_5831363_5 - - - - 0.0001567 54.0
WLSH2_k127_5902353_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 441.0
WLSH2_k127_5902353_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 319.0
WLSH2_k127_5902353_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001073 264.0
WLSH2_k127_5902353_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000007094 67.0
WLSH2_k127_6060057_0 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 391.0
WLSH2_k127_6060057_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 368.0
WLSH2_k127_6060057_10 signal transduction histidine kinase - - - 0.0000000000000000000000005598 121.0
WLSH2_k127_6060057_11 antisigma factor binding K02066,K04749 - - 0.0000000000000000000005946 101.0
WLSH2_k127_6060057_12 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.00000000000000000000744 100.0
WLSH2_k127_6060057_13 - K07283 - - 0.00000000001762 75.0
WLSH2_k127_6060057_14 Belongs to the anti-sigma-factor antagonist family - - - 0.00001148 48.0
WLSH2_k127_6060057_15 PFAM FecR protein - - - 0.00001378 57.0
WLSH2_k127_6060057_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 345.0
WLSH2_k127_6060057_3 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 325.0
WLSH2_k127_6060057_4 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 324.0
WLSH2_k127_6060057_5 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002337 270.0
WLSH2_k127_6060057_6 Putative porin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004355 254.0
WLSH2_k127_6060057_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000002146 222.0
WLSH2_k127_6060057_8 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.00000000000000000000000000000000000000000000000003022 181.0
WLSH2_k127_6060057_9 stage II sporulation K07315 - 3.1.3.3 0.00000000000000000000000000000000001881 155.0
WLSH2_k127_6094003_0 Serine aminopeptidase, S33 K18100 - - 0.00000000000000000000000000000000000000000000000000001411 198.0
WLSH2_k127_6094003_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000122 188.0
WLSH2_k127_6094003_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000003819 136.0
WLSH2_k127_6094003_3 ATPases associated with a variety of cellular activities K02017 - 3.6.3.29 0.00000000000004175 73.0
WLSH2_k127_6097074_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K04085 - - 4.373e-255 797.0
WLSH2_k127_6097074_1 Ammonium Transporter Family K03320 - - 5.995e-212 668.0
WLSH2_k127_6097074_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001333 264.0
WLSH2_k127_6097074_11 Cytochrome C biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000004922 222.0
WLSH2_k127_6097074_12 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000004106 161.0
WLSH2_k127_6097074_13 Nitrogen regulatory protein P-II - - - 0.00000000000000000000000000000000000000006599 153.0
WLSH2_k127_6097074_14 6-phospho-beta-galactosidase activity - - - 0.000000000000000000000000000000000000004004 162.0
WLSH2_k127_6097074_15 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000001709 128.0
WLSH2_k127_6097074_16 - K06992 - - 0.0000000000000000000000000008467 118.0
WLSH2_k127_6097074_17 Acyl-homoserine-lactone synthase - - - 0.00000000000000000000000007061 115.0
WLSH2_k127_6097074_18 Belongs to the UPF0251 family - - - 0.000000000000000000000002078 106.0
WLSH2_k127_6097074_19 - - - - 0.0000000000000000000000698 103.0
WLSH2_k127_6097074_2 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 544.0
WLSH2_k127_6097074_20 Thioredoxin domain - - - 0.000000000000000000001251 96.0
WLSH2_k127_6097074_23 - - - - 0.00000000231 68.0
WLSH2_k127_6097074_25 Tetratricopeptide repeat - - - 0.000007586 60.0
WLSH2_k127_6097074_3 Sodium Bile acid symporter family K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 535.0
WLSH2_k127_6097074_4 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 512.0
WLSH2_k127_6097074_5 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 458.0
WLSH2_k127_6097074_6 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 405.0
WLSH2_k127_6097074_7 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 344.0
WLSH2_k127_6097074_8 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 308.0
WLSH2_k127_6097074_9 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002164 278.0
WLSH2_k127_6106417_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 516.0
WLSH2_k127_6106417_1 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 487.0
WLSH2_k127_6106417_2 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 372.0
WLSH2_k127_6106417_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 341.0
WLSH2_k127_6106417_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 301.0
WLSH2_k127_6106417_5 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000003546 272.0
WLSH2_k127_6106417_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000002477 170.0
WLSH2_k127_6106417_7 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000001785 122.0
WLSH2_k127_6130105_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.054e-310 975.0
WLSH2_k127_6130105_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 359.0
WLSH2_k127_6130105_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000001411 208.0
WLSH2_k127_6130105_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000142 186.0
WLSH2_k127_6130105_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000001047 144.0
WLSH2_k127_6130105_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000003017 124.0
WLSH2_k127_6130105_6 Cell wall formation K01921 - 6.3.2.4 0.0000122 48.0
WLSH2_k127_6130105_7 Cell division protein FtsQ K03589 - - 0.00004235 54.0
WLSH2_k127_6199440_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 413.0
WLSH2_k127_6199440_1 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.00000000000000000000000000000000000000000000000000000000000000000103 244.0
WLSH2_k127_6199440_2 PFAM methyltransferase - - - 0.000000000000000000000000000000000000000000175 174.0
WLSH2_k127_6199440_3 transferase activity, transferring glycosyl groups - - - 0.00000004443 58.0
WLSH2_k127_6229732_0 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 436.0
WLSH2_k127_6229732_1 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 356.0
WLSH2_k127_6229732_2 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 292.0
WLSH2_k127_6229732_3 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000000000000000000000000003243 209.0
WLSH2_k127_6229732_4 - - - - 0.0000000000000000000629 98.0
WLSH2_k127_623971_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 518.0
WLSH2_k127_623971_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 460.0
WLSH2_k127_623971_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001894 178.0
WLSH2_k127_623971_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000002892 165.0
WLSH2_k127_623971_12 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000001721 146.0
WLSH2_k127_623971_13 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000002799 136.0
WLSH2_k127_623971_14 Radical SAM domain protein - - - 0.000000000000000000001156 96.0
WLSH2_k127_623971_15 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000001616 85.0
WLSH2_k127_623971_16 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000001258 84.0
WLSH2_k127_623971_17 exporters of the RND superfamily K07003 - - 0.000000000005143 71.0
WLSH2_k127_623971_18 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000006988 67.0
WLSH2_k127_623971_19 Outer membrane protein (OmpH-like) K06142 - - 0.000000007269 64.0
WLSH2_k127_623971_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 384.0
WLSH2_k127_623971_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 373.0
WLSH2_k127_623971_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 354.0
WLSH2_k127_623971_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 321.0
WLSH2_k127_623971_6 Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 308.0
WLSH2_k127_623971_7 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006718 276.0
WLSH2_k127_623971_8 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000255 261.0
WLSH2_k127_623971_9 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000001145 227.0
WLSH2_k127_6265444_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 9.874e-201 633.0
WLSH2_k127_6265444_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 535.0
WLSH2_k127_6265444_10 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000009144 254.0
WLSH2_k127_6265444_11 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000001235 239.0
WLSH2_k127_6265444_12 PFAM HhH-GPD family protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000000001674 223.0
WLSH2_k127_6265444_13 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000005019 205.0
WLSH2_k127_6265444_14 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000008787 160.0
WLSH2_k127_6265444_15 protein (ATP-grasp superfamily) K07159 - - 0.000000000000000000000000000000000000000003755 168.0
WLSH2_k127_6265444_16 GTP binding K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000004126 149.0
WLSH2_k127_6265444_17 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000000000003353 139.0
WLSH2_k127_6265444_18 PFAM Aminotransferase, class IV K00826,K02619 - 2.6.1.42,4.1.3.38 0.00000000000000000000000000000000008528 144.0
WLSH2_k127_6265444_19 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000001331 145.0
WLSH2_k127_6265444_2 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 482.0
WLSH2_k127_6265444_20 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000009116 124.0
WLSH2_k127_6265444_21 Tetratricopeptide repeat - - - 0.000000000000000000000000002862 117.0
WLSH2_k127_6265444_22 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.00000000000000000000000629 109.0
WLSH2_k127_6265444_23 Uncharacterised conserved protein (DUF2156) K01163,K06940 - - 0.00000000000000000000001045 108.0
WLSH2_k127_6265444_24 domain, Protein - - - 0.00000000000000000007428 105.0
WLSH2_k127_6265444_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 381.0
WLSH2_k127_6265444_4 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 357.0
WLSH2_k127_6265444_5 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 330.0
WLSH2_k127_6265444_6 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 332.0
WLSH2_k127_6265444_7 dihydrofolate synthase activity K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006972 289.0
WLSH2_k127_6265444_8 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002619 266.0
WLSH2_k127_6265444_9 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000003651 245.0
WLSH2_k127_6378380_0 D-isomer specific 2-hydroxyacid dehydrogenase K03778 - 1.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 444.0
WLSH2_k127_6378380_1 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002027 289.0
WLSH2_k127_6378380_2 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD - - - 0.000000000000000000000000000000000000000000000000000000000000000003105 235.0
WLSH2_k127_6378380_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000524 196.0
WLSH2_k127_6378380_4 Cytochrome C biogenesis protein - - - 0.000000000000000000000000000000000000001943 162.0
WLSH2_k127_6378380_5 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000001424 140.0
WLSH2_k127_6378380_6 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000001172 126.0
WLSH2_k127_6378380_7 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.0000000000000000000000000001045 128.0
WLSH2_k127_6378380_8 YGGT family K02221 - - 0.000000000000000000000003345 106.0
WLSH2_k127_6378380_9 EamA-like transporter family K05786 - - 0.00000004244 61.0
WLSH2_k127_649566_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 464.0
WLSH2_k127_649566_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 346.0
WLSH2_k127_649566_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005803 285.0
WLSH2_k127_649566_3 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000005536 170.0
WLSH2_k127_649566_4 rRNA binding K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000003144 102.0
WLSH2_k127_665667_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.22e-217 687.0
WLSH2_k127_665667_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 430.0
WLSH2_k127_665667_10 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000009139 142.0
WLSH2_k127_665667_11 Type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000215 148.0
WLSH2_k127_665667_12 general secretion pathway protein K02453 - - 0.00000000000000000000000000000002176 146.0
WLSH2_k127_665667_13 HD domain - - - 0.00000000000000000000003754 111.0
WLSH2_k127_665667_14 - - - - 0.0000000000000006372 78.0
WLSH2_k127_665667_15 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000007913 89.0
WLSH2_k127_665667_16 Belongs to the thioredoxin family K03671 - - 0.00000002045 55.0
WLSH2_k127_665667_17 YacP-like NYN domain K06962 - - 0.0000001925 59.0
WLSH2_k127_665667_18 Tetratricopeptide TPR_2 repeat protein - - - 0.00001942 59.0
WLSH2_k127_665667_19 Tetratricopeptide TPR_2 repeat protein - - - 0.0004168 52.0
WLSH2_k127_665667_2 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 377.0
WLSH2_k127_665667_3 PFAM Phosphate acetyl butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 289.0
WLSH2_k127_665667_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002103 287.0
WLSH2_k127_665667_5 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000006384 266.0
WLSH2_k127_665667_6 AAA domain K02450 - - 0.00000000000000000000000000000000000000000000000000000000000002716 226.0
WLSH2_k127_665667_7 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000005539 199.0
WLSH2_k127_665667_8 Protein of unknown function (DUF523) - - - 0.00000000000000000000000000000000000000002534 159.0
WLSH2_k127_665667_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000138 150.0
WLSH2_k127_6750101_0 Homeodomain-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 455.0
WLSH2_k127_6750101_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 317.0
WLSH2_k127_6750101_2 Nucleotidyltransferase domain - - - 0.0000000000000000000000446 103.0
WLSH2_k127_6750101_3 Zinc finger, CHC2-type protein - - - 0.000000000000000002056 89.0
WLSH2_k127_689935_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0001098 57.0
WLSH2_k127_690576_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004,K05685 - - 2.806e-221 704.0
WLSH2_k127_690576_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 461.0
WLSH2_k127_690576_10 ZIP Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000001354 185.0
WLSH2_k127_690576_11 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000000000009132 189.0
WLSH2_k127_690576_12 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000002327 192.0
WLSH2_k127_690576_13 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000001134 184.0
WLSH2_k127_690576_14 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000001621 181.0
WLSH2_k127_690576_15 DNA metabolism protein - - - 0.0000000000000000000000000000000006162 140.0
WLSH2_k127_690576_16 Hit family K19710 - 2.7.7.53 0.000000000000000000000000004581 112.0
WLSH2_k127_690576_17 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000000001641 117.0
WLSH2_k127_690576_18 Radical SAM superfamily K22226 - - 0.000000000000000000000002857 115.0
WLSH2_k127_690576_19 YceI-like domain - - - 0.000000001289 66.0
WLSH2_k127_690576_2 DNA modification repair radical SAM protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 448.0
WLSH2_k127_690576_20 - - - - 0.0000551 49.0
WLSH2_k127_690576_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 444.0
WLSH2_k127_690576_4 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 414.0
WLSH2_k127_690576_5 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 320.0
WLSH2_k127_690576_6 TIGRFAM efflux transporter, RND family, MFP subunit K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 306.0
WLSH2_k127_690576_7 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 301.0
WLSH2_k127_690576_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 306.0
WLSH2_k127_690576_9 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009272 252.0
WLSH2_k127_6957970_0 acid) synthase K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 543.0
WLSH2_k127_6957970_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 480.0
WLSH2_k127_6957970_10 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000001459 67.0
WLSH2_k127_6957970_11 ATP synthase, delta epsilon subunit, beta-sandwich domain protein K02114 - - 0.00000005296 59.0
WLSH2_k127_6957970_12 - - - - 0.0000001167 63.0
WLSH2_k127_6957970_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0001172 53.0
WLSH2_k127_6957970_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 459.0
WLSH2_k127_6957970_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 452.0
WLSH2_k127_6957970_4 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 376.0
WLSH2_k127_6957970_5 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001233 272.0
WLSH2_k127_6957970_6 secretion system protein G K02456 - - 0.00000000000000000000000000000004969 131.0
WLSH2_k127_6957970_7 Type II secretion system (T2SS), protein K - - - 0.0000000000000006557 90.0
WLSH2_k127_6957970_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000001664 87.0
WLSH2_k127_6957970_9 PFAM General secretory system II protein E domain protein K11740 - - 0.00000000328 64.0
WLSH2_k127_7034298_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 343.0
WLSH2_k127_7034298_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 312.0
WLSH2_k127_7034298_2 AAA ATPase domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007544 248.0
WLSH2_k127_7034298_3 COG0489 ATPases involved in chromosome partitioning K00903 - 2.7.10.2 0.0000000000000000000000000000000000000000002794 168.0
WLSH2_k127_7034298_4 Prokaryotic diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000103 97.0
WLSH2_k127_7034298_5 polysaccharide export K01991 - - 0.00000000000000003701 92.0
WLSH2_k127_7034298_6 extracellular polysaccharide biosynthetic process K07011 - - 0.00000000000002602 85.0
WLSH2_k127_7034298_7 regulatory protein, MerR - - - 0.0008835 45.0
WLSH2_k127_715547_0 hexose biosynthetic process K01810 - 5.3.1.9 2.3e-278 863.0
WLSH2_k127_715547_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.245e-237 748.0
WLSH2_k127_715547_10 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 287.0
WLSH2_k127_715547_11 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006014 254.0
WLSH2_k127_715547_12 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000002814 229.0
WLSH2_k127_715547_13 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000005491 213.0
WLSH2_k127_715547_14 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000004674 214.0
WLSH2_k127_715547_15 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000001676 209.0
WLSH2_k127_715547_16 Type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000000000559 209.0
WLSH2_k127_715547_17 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000001912 185.0
WLSH2_k127_715547_18 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000296 173.0
WLSH2_k127_715547_19 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000002399 165.0
WLSH2_k127_715547_2 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 418.0
WLSH2_k127_715547_20 DsrE/DsrF-like family K06039 - - 0.00000000000000000000000000000000000001088 147.0
WLSH2_k127_715547_21 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000003793 148.0
WLSH2_k127_715547_22 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000001021 148.0
WLSH2_k127_715547_23 Reverse transcriptase-like K03469 - 3.1.26.4 0.0000000000000000000000000000000001265 138.0
WLSH2_k127_715547_24 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000002188 134.0
WLSH2_k127_715547_25 pilus assembly protein K02662 - - 0.000000000000000000000000000006603 132.0
WLSH2_k127_715547_26 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000002836 107.0
WLSH2_k127_715547_28 Pfam:N_methyl_2 - - - 0.000000000000000000004703 98.0
WLSH2_k127_715547_29 cheY-homologous receiver domain - - - 0.00000000000000000002577 97.0
WLSH2_k127_715547_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 389.0
WLSH2_k127_715547_30 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.000000000000000001945 94.0
WLSH2_k127_715547_31 Radical SAM-linked protein - - - 0.00000000000002237 76.0
WLSH2_k127_715547_32 Cupin 2, conserved barrel domain protein - - - 0.00000000000009066 75.0
WLSH2_k127_715547_33 STAS domain K04749 - - 0.0000000002356 70.0
WLSH2_k127_715547_34 - - - - 0.00003261 50.0
WLSH2_k127_715547_4 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 394.0
WLSH2_k127_715547_5 PFAM penicillin-binding protein transpeptidase K17838 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 368.0
WLSH2_k127_715547_6 Prephenate dehydratase K00661,K01713,K04092,K04093,K04516,K04518,K14170,K14187 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,2.3.1.79,4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 366.0
WLSH2_k127_715547_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 353.0
WLSH2_k127_715547_8 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 336.0
WLSH2_k127_715547_9 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 317.0
WLSH2_k127_7231531_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0 1210.0
WLSH2_k127_7231531_1 PFAM Radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 610.0
WLSH2_k127_7231531_2 PFAM Uracil-DNA glycosylase superfamily K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 285.0
WLSH2_k127_7231531_3 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000001306 164.0
WLSH2_k127_7231531_4 Protein of unknown function DUF134 - - - 0.000000000000000000000000000002578 122.0
WLSH2_k127_7231531_5 - - - - 0.00000000000000000000000001886 114.0
WLSH2_k127_7231531_6 Psort location Cytoplasmic, score 8.96 K08303 - - 0.0000000007154 62.0
WLSH2_k127_7367296_0 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000003249 253.0
WLSH2_k127_7367296_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000001498 224.0
WLSH2_k127_7367296_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000001279 132.0
WLSH2_k127_7367296_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000001474 113.0
WLSH2_k127_7367296_4 Transcriptional regulator K13640 - - 0.000000003279 61.0
WLSH2_k127_7420612_0 PFAM Glycosyltransferase family 28 C-terminal domain K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000297 208.0
WLSH2_k127_7420612_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000007175 182.0
WLSH2_k127_7420612_2 PFAM Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000001454 141.0
WLSH2_k127_7420612_3 Polysaccharide biosynthesis protein - - - 0.000000004719 66.0
WLSH2_k127_7475453_0 PFAM RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 450.0
WLSH2_k127_7475453_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 379.0
WLSH2_k127_7475453_2 PFAM tRNA pseudouridine synthase D TruD K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 333.0
WLSH2_k127_7475453_3 TonB-dependent Receptor Plug K02014,K16089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 326.0
WLSH2_k127_7475453_4 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000002011 171.0
WLSH2_k127_7475453_5 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000001058 119.0
WLSH2_k127_7475453_6 Protein of unknown function (DUF503) K09764 - - 0.0000000000000001418 83.0
WLSH2_k127_7480685_0 COG0668 Small-conductance mechanosensitive channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 315.0
WLSH2_k127_7480685_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004492 252.0
WLSH2_k127_7480685_2 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000001702 244.0
WLSH2_k127_7480685_3 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000003339 168.0
WLSH2_k127_7588280_0 4Fe-4S single cluster domain K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 417.0
WLSH2_k127_7588280_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 411.0
WLSH2_k127_7588280_2 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 286.0
WLSH2_k127_7588280_4 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.0005883 50.0
WLSH2_k127_7668606_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002933 272.0
WLSH2_k127_7668606_1 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000002585 229.0
WLSH2_k127_7668606_2 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000001871 223.0
WLSH2_k127_7668606_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000001064 218.0
WLSH2_k127_7668606_4 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000002023 175.0
WLSH2_k127_7668606_5 adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000004589 168.0
WLSH2_k127_7668606_6 PFAM Phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.00000000000000000000000005183 118.0
WLSH2_k127_7668606_7 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000004701 70.0
WLSH2_k127_7668606_8 Belongs to the Nudix hydrolase family - - - 0.0001945 46.0
WLSH2_k127_7869358_0 Response regulator receiver K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000000000000000000000001235 135.0
WLSH2_k127_7990107_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 505.0
WLSH2_k127_7990107_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 486.0
WLSH2_k127_7990107_10 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 319.0
WLSH2_k127_7990107_11 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 319.0
WLSH2_k127_7990107_12 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 300.0
WLSH2_k127_7990107_13 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002769 285.0
WLSH2_k127_7990107_14 NAD dependent epimerase dehydratase family K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003132 285.0
WLSH2_k127_7990107_15 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002101 239.0
WLSH2_k127_7990107_17 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000012 138.0
WLSH2_k127_7990107_18 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000001486 154.0
WLSH2_k127_7990107_19 membrane - - - 0.00000000000000000000000006489 124.0
WLSH2_k127_7990107_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 428.0
WLSH2_k127_7990107_20 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000002254 98.0
WLSH2_k127_7990107_21 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000002437 67.0
WLSH2_k127_7990107_3 Dolichol monophosphate mannose synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 409.0
WLSH2_k127_7990107_4 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 413.0
WLSH2_k127_7990107_5 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 382.0
WLSH2_k127_7990107_6 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 374.0
WLSH2_k127_7990107_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 340.0
WLSH2_k127_7990107_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 340.0
WLSH2_k127_7990107_9 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 335.0
WLSH2_k127_8143817_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.747e-208 660.0
WLSH2_k127_8143817_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 605.0
WLSH2_k127_8143817_2 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 523.0
WLSH2_k127_8150172_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1019.0
WLSH2_k127_8150172_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 430.0
WLSH2_k127_8150172_10 - - - - 0.00000000000000001369 85.0
WLSH2_k127_8150172_11 Transcriptional regulator K13640 - - 0.000000001106 62.0
WLSH2_k127_8150172_12 Colicin V production protein K03558 - - 0.0000003951 59.0
WLSH2_k127_8150172_13 Glycosyl transferase family 41 - - - 0.00000085 61.0
WLSH2_k127_8150172_14 PFAM Sporulation related domain - - - 0.00001571 55.0
WLSH2_k127_8150172_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 385.0
WLSH2_k127_8150172_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 350.0
WLSH2_k127_8150172_4 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 316.0
WLSH2_k127_8150172_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 311.0
WLSH2_k127_8150172_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000006731 248.0
WLSH2_k127_8150172_7 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000003349 195.0
WLSH2_k127_8150172_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000003913 168.0
WLSH2_k127_8150172_9 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001263 153.0
WLSH2_k127_8157750_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1416.0
WLSH2_k127_8157750_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 498.0
WLSH2_k127_8157750_10 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000001202 117.0
WLSH2_k127_8157750_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 439.0
WLSH2_k127_8157750_3 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 434.0
WLSH2_k127_8157750_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 412.0
WLSH2_k127_8157750_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 386.0
WLSH2_k127_8157750_6 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 332.0
WLSH2_k127_8157750_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000001712 248.0
WLSH2_k127_8157750_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000004685 244.0
WLSH2_k127_8157750_9 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000000000004289 220.0
WLSH2_k127_8209921_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 368.0
WLSH2_k127_8209921_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000002903 222.0
WLSH2_k127_8209921_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000002533 186.0
WLSH2_k127_8209921_3 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000002183 149.0
WLSH2_k127_8211166_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 5.762e-297 925.0
WLSH2_k127_8211166_1 Ferrous iron transport protein B K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 605.0
WLSH2_k127_8211166_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 578.0
WLSH2_k127_8211166_3 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 438.0
WLSH2_k127_8211166_4 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001115 287.0
WLSH2_k127_8211166_6 PFAM FeoA K04758 - - 0.000000259 55.0
WLSH2_k127_8390334_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.281e-239 752.0
WLSH2_k127_8390334_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 367.0
WLSH2_k127_8390334_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004116 256.0
WLSH2_k127_8390334_4 - - - - 0.0000000588 56.0
WLSH2_k127_8486654_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.238e-204 656.0
WLSH2_k127_8486654_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 432.0
WLSH2_k127_8486654_10 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000008951 175.0
WLSH2_k127_8486654_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000002861 168.0
WLSH2_k127_8486654_12 cyclic-guanylate-specific phosphodiesterase activity - - - 0.0000000000000000000000000000000000000002467 167.0
WLSH2_k127_8486654_13 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000008872 107.0
WLSH2_k127_8486654_14 Pfam:Methyltransf_26 - - - 0.000000000000000000006835 94.0
WLSH2_k127_8486654_15 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000001374 82.0
WLSH2_k127_8486654_2 recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 309.0
WLSH2_k127_8486654_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 296.0
WLSH2_k127_8486654_4 CBS domain containing protein K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003648 283.0
WLSH2_k127_8486654_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000001159 265.0
WLSH2_k127_8486654_6 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000384 246.0
WLSH2_k127_8486654_7 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000001948 220.0
WLSH2_k127_8486654_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000002129 213.0
WLSH2_k127_8486654_9 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000746 215.0
WLSH2_k127_8511327_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.091e-211 666.0
WLSH2_k127_8511327_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 527.0
WLSH2_k127_8511327_11 Belongs to the peptidase S8 family - - - 0.0000002084 61.0
WLSH2_k127_8511327_12 zinc-ribbon domain - - - 0.00001926 51.0
WLSH2_k127_8511327_2 V-type ATP synthase, subunit I K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 346.0
WLSH2_k127_8511327_3 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003103 243.0
WLSH2_k127_8511327_4 Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000000000000000000699 206.0
WLSH2_k127_8511327_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000006045 181.0
WLSH2_k127_8511327_6 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.000000000000000000000000000000000000000002511 162.0
WLSH2_k127_8511327_7 ATP synthase subunit K K02124 - - 0.0000000000000000000000000000000000000005671 153.0
WLSH2_k127_8511327_8 - - - - 0.0000000000000000000000000000000001121 138.0
WLSH2_k127_8511327_9 protein conserved in bacteria - - - 0.0000000000000000001554 102.0
WLSH2_k127_8527800_0 Glycogen debranching enzyme - - - 0.0 1235.0
WLSH2_k127_8527800_1 sulphate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 550.0
WLSH2_k127_8527800_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 501.0
WLSH2_k127_8527800_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006377 270.0
WLSH2_k127_8527800_4 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000002061 222.0
WLSH2_k127_8527800_5 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000001057 163.0
WLSH2_k127_8527800_6 - - - - 0.00000000000000000001321 98.0
WLSH2_k127_8527800_7 Protein of unknown function (DUF2950) - - - 0.00000000000000000003369 91.0
WLSH2_k127_8527800_8 YMGG-like Gly-zipper - - - 0.00000000001591 71.0
WLSH2_k127_8541695_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 4.125e-321 996.0
WLSH2_k127_8541695_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 576.0
WLSH2_k127_8541695_2 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 327.0
WLSH2_k127_8541695_3 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000001074 64.0
WLSH2_k127_8579677_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 5.445e-241 765.0
WLSH2_k127_8579677_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.661e-238 745.0
WLSH2_k127_8579677_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000005075 187.0
WLSH2_k127_8579677_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000001382 172.0
WLSH2_k127_8579677_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000001313 132.0
WLSH2_k127_8579677_5 Ankyrin repeats (many copies) K21440 - - 0.0000000000005699 74.0
WLSH2_k127_8581500_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 344.0
WLSH2_k127_8581500_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 341.0
WLSH2_k127_8581500_2 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000005052 188.0
WLSH2_k127_8581500_3 Predicted membrane protein (DUF2207) - - - 0.0000000000001511 74.0
WLSH2_k127_8748422_0 Pilus assembly protein PilX - - - 0.000000000000001424 89.0
WLSH2_k127_8748422_1 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000001141 81.0
WLSH2_k127_8748422_2 Nitroreductase family - - - 0.00000000001127 75.0
WLSH2_k127_8748422_3 pilus assembly protein PilW K02672 - - 0.0002712 49.0
WLSH2_k127_8748422_4 type IV pilus modification protein PilV K02671 - - 0.0004832 49.0
WLSH2_k127_8926077_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 416.0
WLSH2_k127_8926077_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 405.0
WLSH2_k127_8926077_2 NAD dependent epimerase dehydratase - - - 0.000000000000000000000000000000202 134.0
WLSH2_k127_8926077_3 repeat-containing protein - - - 0.000000000000001907 80.0
WLSH2_k127_8926077_4 Alginate export - - - 0.000000000000003957 88.0
WLSH2_k127_897748_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 447.0
WLSH2_k127_897748_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001115 281.0
WLSH2_k127_897748_2 PFAM Oligosaccharyl transferase STT3 subunit K07151,K21306 - 2.4.99.18,2.4.99.21 0.00000000000000000000000000000000000000000000000000003613 214.0
WLSH2_k127_897748_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000001418 183.0
WLSH2_k127_897748_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000003207 141.0
WLSH2_k127_897748_5 Belongs to the UPF0102 family K07460 - - 0.0008996 43.0
WLSH2_k127_901737_0 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000007052 164.0
WLSH2_k127_901737_1 Cupin domain K11312 - - 0.0000000000000000000000000001806 117.0
WLSH2_k127_902245_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.218e-222 695.0
WLSH2_k127_902245_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 573.0
WLSH2_k127_902245_10 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 288.0
WLSH2_k127_902245_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003338 277.0
WLSH2_k127_902245_12 TIGRFAM methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001001 252.0
WLSH2_k127_902245_13 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000003301 206.0
WLSH2_k127_902245_14 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000004168 211.0
WLSH2_k127_902245_15 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000002883 173.0
WLSH2_k127_902245_16 Divergent PAP2 family K09775 - - 0.000000000000000000000000000000000002637 143.0
WLSH2_k127_902245_17 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000973 105.0
WLSH2_k127_902245_18 Transcriptional regulator PadR-like family - - - 0.00000000000000004044 88.0
WLSH2_k127_902245_19 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000007826 70.0
WLSH2_k127_902245_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 518.0
WLSH2_k127_902245_3 cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 447.0
WLSH2_k127_902245_4 malonyl-CoA biosynthetic process K01962,K01963 GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 390.0
WLSH2_k127_902245_5 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 342.0
WLSH2_k127_902245_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 342.0
WLSH2_k127_902245_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 332.0
WLSH2_k127_902245_8 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 320.0
WLSH2_k127_902245_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 298.0
WLSH2_k127_9092536_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001037 269.0
WLSH2_k127_9092536_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000002091 247.0
WLSH2_k127_9140401_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 473.0
WLSH2_k127_9140401_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 460.0
WLSH2_k127_9140401_10 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000003691 234.0
WLSH2_k127_9140401_11 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000001442 239.0
WLSH2_k127_9140401_12 Monogalactosyldiacylglycerol synthase K03429,K03715 - 2.4.1.315,2.4.1.46 0.0000000000000000000000000000000000000000001945 173.0
WLSH2_k127_9140401_13 - - - - 0.00000000000000000000000000000000000009204 154.0
WLSH2_k127_9140401_14 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000006604 146.0
WLSH2_k127_9140401_15 superoxide reductase activity K05919 - 1.15.1.2 0.0000000000000000000000000000000003835 136.0
WLSH2_k127_9140401_16 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000009787 117.0
WLSH2_k127_9140401_17 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.0000000000000000006129 95.0
WLSH2_k127_9140401_19 von Willebrand factor, type A K07114 - - 0.0005588 51.0
WLSH2_k127_9140401_2 4-alpha-glucanotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 424.0
WLSH2_k127_9140401_3 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 387.0
WLSH2_k127_9140401_4 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 370.0
WLSH2_k127_9140401_5 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 333.0
WLSH2_k127_9140401_6 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 323.0
WLSH2_k127_9140401_7 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 314.0
WLSH2_k127_9140401_8 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002255 275.0
WLSH2_k127_9140401_9 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003415 271.0
WLSH2_k127_9173609_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 553.0
WLSH2_k127_9173609_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 321.0
WLSH2_k127_9173609_2 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001083 217.0
WLSH2_k127_9173609_3 Flavodoxin - - - 0.0000000000000000000000000000000000000001365 155.0
WLSH2_k127_9173609_4 PFAM AsmA family protein K07289 - - 0.0000000001801 74.0
WLSH2_k127_9173609_5 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000001547 53.0
WLSH2_k127_920648_0 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 484.0
WLSH2_k127_920648_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 345.0
WLSH2_k127_920648_10 oxidation-reduction process - - - 0.0000000000000000000000000000000441 135.0
WLSH2_k127_920648_11 Polyketide cyclase / dehydrase and lipid transport K14670 - - 0.0000000000000000000000000000001968 128.0
WLSH2_k127_920648_12 Sugar (and other) transporter - - - 0.000000000000000000000000000002834 134.0
WLSH2_k127_920648_13 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000001021 76.0
WLSH2_k127_920648_14 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 0.00000000001586 74.0
WLSH2_k127_920648_15 hydrogenase expression formation protein K03605 - - 0.00000002459 60.0
WLSH2_k127_920648_16 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.00001376 51.0
WLSH2_k127_920648_2 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 346.0
WLSH2_k127_920648_3 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 334.0
WLSH2_k127_920648_4 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 314.0
WLSH2_k127_920648_5 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 290.0
WLSH2_k127_920648_6 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009579 242.0
WLSH2_k127_920648_7 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000000000000005055 208.0
WLSH2_k127_920648_8 B12 binding domain K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000008287 205.0
WLSH2_k127_920648_9 amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000002178 141.0
WLSH2_k127_9357993_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.443e-210 671.0
WLSH2_k127_9357993_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 554.0
WLSH2_k127_9357993_10 Fe-S iron-sulfur cluster assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000001345 185.0
WLSH2_k127_9357993_11 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000001771 167.0
WLSH2_k127_9357993_12 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000004443 131.0
WLSH2_k127_9357993_13 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000000000000000000000000174 128.0
WLSH2_k127_9357993_14 - - - - 0.000000000000000000000000000002956 126.0
WLSH2_k127_9357993_15 - - - - 0.0000003161 54.0
WLSH2_k127_9357993_2 AAA ATPase, central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 479.0
WLSH2_k127_9357993_3 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 466.0
WLSH2_k127_9357993_4 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 391.0
WLSH2_k127_9357993_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 373.0
WLSH2_k127_9357993_6 protein conserved in bacteria K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004099 276.0
WLSH2_k127_9357993_7 domain protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000001376 214.0
WLSH2_k127_9357993_8 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000005455 201.0
WLSH2_k127_9357993_9 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000001393 193.0
WLSH2_k127_938161_0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003972 291.0
WLSH2_k127_938161_1 PFAM ROK family protein - - - 0.000000000000000000000000000000000000000001229 172.0
WLSH2_k127_938161_2 Bacterial regulatory proteins, lacI family K02529 - - 0.00000000000000000000000000001205 126.0
WLSH2_k127_9483516_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1271.0
WLSH2_k127_9483516_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 1.685e-314 989.0
WLSH2_k127_9483516_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 355.0
WLSH2_k127_9483516_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 331.0
WLSH2_k127_9483516_12 conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 322.0
WLSH2_k127_9483516_13 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003155 273.0
WLSH2_k127_9483516_14 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003153 245.0
WLSH2_k127_9483516_15 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000001026 240.0
WLSH2_k127_9483516_16 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000471 234.0
WLSH2_k127_9483516_17 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000001998 210.0
WLSH2_k127_9483516_18 With S4 and S5 plays an important role in translational accuracy K02950 - - 0.00000000000000000000000000000000000000000000000000000000002298 209.0
WLSH2_k127_9483516_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000004121 205.0
WLSH2_k127_9483516_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.204e-270 850.0
WLSH2_k127_9483516_20 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000195 208.0
WLSH2_k127_9483516_21 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001005 199.0
WLSH2_k127_9483516_22 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000001006 207.0
WLSH2_k127_9483516_23 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K22110 - - 0.00000000000000000000000000000000000000000000000000008493 203.0
WLSH2_k127_9483516_24 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000004719 167.0
WLSH2_k127_9483516_25 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000005372 169.0
WLSH2_k127_9483516_26 - K06992 - - 0.0000000000000000000000000000000000000001071 159.0
WLSH2_k127_9483516_27 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000007679 151.0
WLSH2_k127_9483516_28 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000001041 145.0
WLSH2_k127_9483516_29 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000181 138.0
WLSH2_k127_9483516_3 Heat shock 70 kDa protein K04043 - - 1.856e-263 825.0
WLSH2_k127_9483516_30 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000007025 129.0
WLSH2_k127_9483516_31 metal-dependent phosphoesterases (PHP family) - - - 0.0000000000000000000000000001625 123.0
WLSH2_k127_9483516_32 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000001812 122.0
WLSH2_k127_9483516_33 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000002949 107.0
WLSH2_k127_9483516_34 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000004391 111.0
WLSH2_k127_9483516_35 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000003112 105.0
WLSH2_k127_9483516_36 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000005244 99.0
WLSH2_k127_9483516_37 deacetylase - - - 0.0000000000000000000002075 110.0
WLSH2_k127_9483516_38 FmdB family - - - 0.0000000000000000000004741 98.0
WLSH2_k127_9483516_39 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000009614 98.0
WLSH2_k127_9483516_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 2.459e-199 626.0
WLSH2_k127_9483516_40 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000001036 111.0
WLSH2_k127_9483516_41 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000009883 88.0
WLSH2_k127_9483516_42 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000006066 86.0
WLSH2_k127_9483516_43 VanZ like family - - - 0.000000000000672 73.0
WLSH2_k127_9483516_44 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000001875 64.0
WLSH2_k127_9483516_45 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00002911 49.0
WLSH2_k127_9483516_46 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00006219 47.0
WLSH2_k127_9483516_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 566.0
WLSH2_k127_9483516_6 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 490.0
WLSH2_k127_9483516_7 PFAM ABC transporter related K05816,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 455.0
WLSH2_k127_9483516_8 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 441.0
WLSH2_k127_9483516_9 rRNA binding K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 372.0
WLSH2_k127_9500760_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 555.0
WLSH2_k127_9500760_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 559.0
WLSH2_k127_9500760_10 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00003044 55.0
WLSH2_k127_9500760_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 482.0
WLSH2_k127_9500760_3 PFAM aminotransferase class V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 409.0
WLSH2_k127_9500760_4 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 310.0
WLSH2_k127_9500760_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 283.0
WLSH2_k127_9500760_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000009627 103.0
WLSH2_k127_9500760_7 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000001843 68.0
WLSH2_k127_9500760_8 AMP catabolic process K19970 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006195,GO:0006196,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0008198,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009889,GO:0009891,GO:0009893,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010044,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0019216,GO:0019222,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0022610,GO:0031224,GO:0031347,GO:0031348,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032501,GO:0032502,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042221,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044464,GO:0045202,GO:0045834,GO:0046033,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046889,GO:0046890,GO:0046914,GO:0048513,GO:0048518,GO:0048519,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050727,GO:0050728,GO:0050789,GO:0050896,GO:0051186,GO:0055086,GO:0060322,GO:0065007,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0080090,GO:0080134,GO:0090304,GO:0090407,GO:0097060,GO:0098590,GO:0098609,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.1.3.5 0.0000002542 64.0
WLSH2_k127_9500760_9 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.000003146 59.0
WLSH2_k127_9573032_0 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1012.0
WLSH2_k127_9573032_1 PFAM Glycoside hydrolase 15-related - - - 2.441e-291 919.0
WLSH2_k127_9573032_10 CobQ/CobB/MinD/ParA nucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 358.0
WLSH2_k127_9573032_11 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 349.0
WLSH2_k127_9573032_12 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 340.0
WLSH2_k127_9573032_13 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 334.0
WLSH2_k127_9573032_14 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 336.0
WLSH2_k127_9573032_15 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 336.0
WLSH2_k127_9573032_16 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 302.0
WLSH2_k127_9573032_17 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
WLSH2_k127_9573032_18 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K02485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003828 274.0
WLSH2_k127_9573032_19 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003359 253.0
WLSH2_k127_9573032_2 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 593.0
WLSH2_k127_9573032_20 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000001428 245.0
WLSH2_k127_9573032_21 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000002913 224.0
WLSH2_k127_9573032_22 GHKL domain - - - 0.00000000000000000000000000000000000000000000000000000000004372 223.0
WLSH2_k127_9573032_23 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000001369 209.0
WLSH2_k127_9573032_24 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000001493 207.0
WLSH2_k127_9573032_25 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000002931 218.0
WLSH2_k127_9573032_26 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000005487 204.0
WLSH2_k127_9573032_27 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000004926 199.0
WLSH2_k127_9573032_28 Metal-dependent hydrolase of the beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000005006 186.0
WLSH2_k127_9573032_29 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000003601 180.0
WLSH2_k127_9573032_3 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 541.0
WLSH2_k127_9573032_30 PD-(D/E)XK endonuclease - - - 0.00000000000000000000000000000000000000000000002974 174.0
WLSH2_k127_9573032_31 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000005978 173.0
WLSH2_k127_9573032_32 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000001045 164.0
WLSH2_k127_9573032_33 Methanogenesis marker protein 8 - - - 0.00000000000000000000000000000000000000000414 167.0
WLSH2_k127_9573032_34 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000001378 170.0
WLSH2_k127_9573032_35 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000006018 156.0
WLSH2_k127_9573032_36 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000001419 149.0
WLSH2_k127_9573032_37 GGDEF domain K01768,K20977 - 4.6.1.1 0.00000000000000000000000000000000000001062 157.0
WLSH2_k127_9573032_38 Competence protein ComEC K02238 - - 0.00000000000000000000000000000000004342 153.0
WLSH2_k127_9573032_39 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000002556 126.0
WLSH2_k127_9573032_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 539.0
WLSH2_k127_9573032_40 MotA TolQ ExbB proton channel family K03561 - - 0.000000000000000000000000000001394 128.0
WLSH2_k127_9573032_41 response regulator, receiver - - - 0.00000000000000000000000002188 113.0
WLSH2_k127_9573032_42 AhpC/TSA family - - - 0.000000000000000000000000895 112.0
WLSH2_k127_9573032_43 phosphorelay signal transduction system - - - 0.00000000000000000000000244 107.0
WLSH2_k127_9573032_44 response regulator - - - 0.000000000000000000000002609 106.0
WLSH2_k127_9573032_45 Protein of unknown function (DUF3185) - - - 0.000000000000000000000008633 101.0
WLSH2_k127_9573032_46 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.0000000000000000000001482 101.0
WLSH2_k127_9573032_47 response regulator - - - 0.000000000000000000000573 101.0
WLSH2_k127_9573032_48 Nitrogen-fixing NifU domain protein K04488 - - 0.0000000000000000000008271 99.0
WLSH2_k127_9573032_49 FMN binding K03612,K03613,K21559 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009279,GO:0016020,GO:0016491,GO:0016651,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000129 93.0
WLSH2_k127_9573032_5 Histidine kinase K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 522.0
WLSH2_k127_9573032_50 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.000000000000000001581 93.0
WLSH2_k127_9573032_51 Alpha/beta hydrolase family - - - 0.0000000000000001704 90.0
WLSH2_k127_9573032_52 Family of unknown function (DUF5320) - - - 0.000000000000000764 81.0
WLSH2_k127_9573032_53 Transglycosylase associated protein - - - 0.00000000000003768 75.0
WLSH2_k127_9573032_54 domain protein K07814 - - 0.000000000002004 72.0
WLSH2_k127_9573032_55 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000004189 71.0
WLSH2_k127_9573032_56 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000004254 67.0
WLSH2_k127_9573032_57 Helix-hairpin-helix motif K02237 - - 0.000000000009326 71.0
WLSH2_k127_9573032_58 4Fe-4S binding domain K03616 - - 0.00000000001044 67.0
WLSH2_k127_9573032_59 methyltransferase - - - 0.00000000005184 71.0
WLSH2_k127_9573032_6 PKD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 458.0
WLSH2_k127_9573032_60 transcriptional regulator - - - 0.00000000005596 66.0
WLSH2_k127_9573032_61 Phospholipase_D-nuclease N-terminal - - - 0.0000000001587 63.0
WLSH2_k127_9573032_63 protein ExbD TolR K03559 - - 0.0000000479 60.0
WLSH2_k127_9573032_65 - - - - 0.0000009689 59.0
WLSH2_k127_9573032_66 Entericidin - - - 0.0003688 44.0
WLSH2_k127_9573032_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 432.0
WLSH2_k127_9573032_8 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 426.0
WLSH2_k127_9573032_9 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 399.0
WLSH2_k127_9659905_0 TIGRFAM DNA polymerase III, alpha subunit K02337,K14162 - 2.7.7.7 1.257e-280 888.0
WLSH2_k127_9659905_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 534.0
WLSH2_k127_9659905_2 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 377.0
WLSH2_k127_9659905_3 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 331.0
WLSH2_k127_9659905_4 Phosphate starvation protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 319.0
WLSH2_k127_9659905_5 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000009379 105.0
WLSH2_k127_9659905_6 Belongs to the bacterial histone-like protein family K03530,K05788 - - 0.000000000000000000002753 95.0
WLSH2_k127_9659905_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000002434 92.0
WLSH2_k127_9659905_8 peptidoglycan-binding protein, lysm - - - 0.0000000001465 71.0
WLSH2_k127_9659905_9 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.0000000001975 68.0
WLSH2_k127_9660175_0 ABC transporter C-terminal domain K15738 - - 6.99e-218 692.0
WLSH2_k127_9660175_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 449.0
WLSH2_k127_9660175_10 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 349.0
WLSH2_k127_9660175_11 PFAM Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 326.0
WLSH2_k127_9660175_12 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K03387 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 306.0
WLSH2_k127_9660175_13 PFAM DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002002 257.0
WLSH2_k127_9660175_14 Belongs to the helicase family. UvrD subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007478 278.0
WLSH2_k127_9660175_15 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000314 244.0
WLSH2_k127_9660175_16 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000004154 223.0
WLSH2_k127_9660175_17 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000004468 216.0
WLSH2_k127_9660175_18 Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000521 216.0
WLSH2_k127_9660175_19 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.0000000000000000000000000000000000000000000000000000007225 203.0
WLSH2_k127_9660175_2 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 432.0
WLSH2_k127_9660175_20 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000007418 186.0
WLSH2_k127_9660175_21 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000001438 168.0
WLSH2_k127_9660175_22 - - - - 0.00000000000000000000000000000000000000000233 165.0
WLSH2_k127_9660175_23 Belongs to the Fur family K09825 - - 0.000000000000000000000000000000000316 136.0
WLSH2_k127_9660175_24 Belongs to the SpoVG family K06412 - - 0.0000000000000000000000000003573 118.0
WLSH2_k127_9660175_25 Protein of unknown function (DUF1456) - - - 0.0000000000000000000000000004236 115.0
WLSH2_k127_9660175_26 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000158 114.0
WLSH2_k127_9660175_27 repeat-containing protein - - - 0.00000000000000000000000002106 121.0
WLSH2_k127_9660175_28 Thioredoxin-like - - - 0.00000000000000000000000007822 117.0
WLSH2_k127_9660175_29 - - - - 0.000000000000000000000001933 107.0
WLSH2_k127_9660175_3 flavodoxin nitric oxide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 414.0
WLSH2_k127_9660175_30 rubredoxin - - - 0.000000000000000000000003496 103.0
WLSH2_k127_9660175_31 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000001602 96.0
WLSH2_k127_9660175_32 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000002885 105.0
WLSH2_k127_9660175_33 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K18358 - 1.2.1.58,1.2.7.1 0.0000000000000000009461 89.0
WLSH2_k127_9660175_34 Heavy-metal-associated domain - - - 0.00000000000002565 77.0
WLSH2_k127_9660175_35 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.0000000000001542 73.0
WLSH2_k127_9660175_36 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000002269 66.0
WLSH2_k127_9660175_37 Belongs to the thioredoxin family K03671 - - 0.00000000007555 72.0
WLSH2_k127_9660175_38 - - - - 0.00000006147 61.0
WLSH2_k127_9660175_39 Heavy-metal-associated domain - - - 0.0000001114 60.0
WLSH2_k127_9660175_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 409.0
WLSH2_k127_9660175_40 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000005984 62.0
WLSH2_k127_9660175_42 Yip1 domain - - - 0.000005247 58.0
WLSH2_k127_9660175_5 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 419.0
WLSH2_k127_9660175_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 378.0
WLSH2_k127_9660175_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 371.0
WLSH2_k127_9660175_8 Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 358.0
WLSH2_k127_9660175_9 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 342.0
WLSH2_k127_9667346_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 4.567e-312 978.0
WLSH2_k127_9667346_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 393.0
WLSH2_k127_9667346_10 Binds directly to 16S ribosomal RNA K02968 - - 0.0000001514 56.0
WLSH2_k127_9667346_11 Lipopolysaccharide-assembly - - - 0.00005935 52.0
WLSH2_k127_9667346_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 325.0
WLSH2_k127_9667346_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 296.0
WLSH2_k127_9667346_4 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 291.0
WLSH2_k127_9667346_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005764 277.0
WLSH2_k127_9667346_6 Outer membrane lipoprotein K05807 - - 0.000000000000000000000000000000000000000000003366 178.0
WLSH2_k127_9667346_7 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000823 143.0
WLSH2_k127_9667346_8 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000009661 114.0
WLSH2_k127_9667346_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000001554 98.0
WLSH2_k127_9762264_0 Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 368.0
WLSH2_k127_9762264_1 AMMECR1 K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 338.0
WLSH2_k127_9762264_2 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 298.0
WLSH2_k127_9762264_3 TrkA-C domain - - - 0.000000000000000000000000000000000000000000000000000000000000365 219.0
WLSH2_k127_9762264_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000001767 126.0
WLSH2_k127_9762264_5 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000974 62.0
WLSH2_k127_9771117_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1216.0
WLSH2_k127_9771117_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.256e-230 724.0
WLSH2_k127_9771117_2 ATP synthase alpha/beta family, beta-barrel domain K02118 - - 3.747e-230 719.0
WLSH2_k127_9771117_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007125 259.0
WLSH2_k127_9771117_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000004726 209.0
WLSH2_k127_9771117_5 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000001762 171.0
WLSH2_k127_9992295_0 DNA topoisomerase II activity K02469 - 5.99.1.3 0.0 1018.0
WLSH2_k127_9992295_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.616e-261 826.0
WLSH2_k127_9992295_2 PFAM Type II secretion system protein E K02283,K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 537.0
WLSH2_k127_9992295_3 PFAM type II and III secretion system protein K02280 - - 0.00000000000000000000000000000000000000000000000008854 197.0
WLSH2_k127_9992295_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000001341 126.0
WLSH2_k127_9992295_5 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000009328 109.0
WLSH2_k127_9992295_6 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000005785 95.0
WLSH2_k127_9992295_7 peptidyl-prolyl cis-trans isomerase activity K03769,K03770,K03771,K07533 - 5.2.1.8 0.000008862 57.0
WLSH2_k127_9992295_8 Protein of unknown function (DUF721) - - - 0.00005738 49.0