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Overview

ID MAG04206
Name WLSH2_bin.31
Sample SMP0110
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order UBA10834
Family UBA10834
Genus UBA9653
Species
Assembly information
Completeness (%) 83.86
Contamination (%) 4.06
GC content (%) 62.0
N50 (bp) 16,764
Genome size (bp) 1,670,317

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1488

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10234037_0 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 466.0
WLSH2_k127_10234037_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 401.0
WLSH2_k127_10234037_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 374.0
WLSH2_k127_10234037_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 337.0
WLSH2_k127_10234037_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005158 275.0
WLSH2_k127_10279703_0 AAA domain K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 409.0
WLSH2_k127_10279703_1 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000001165 114.0
WLSH2_k127_10279703_2 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000001092 86.0
WLSH2_k127_10279703_3 PFAM PKD domain containing protein - - - 0.00000000000006181 83.0
WLSH2_k127_10355026_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1051.0
WLSH2_k127_10355026_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 9.824e-218 702.0
WLSH2_k127_10355026_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000002672 147.0
WLSH2_k127_10355026_11 Universal stress protein family - - - 0.000000000000000000000000000000003716 135.0
WLSH2_k127_10355026_12 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.00000000000000000005519 91.0
WLSH2_k127_10355026_13 - - - - 0.00000000000000000007318 94.0
WLSH2_k127_10355026_14 ThiS family K03636 - - 0.000000000000000000989 89.0
WLSH2_k127_10355026_15 PAP2 superfamily - - - 0.000000000000000008072 94.0
WLSH2_k127_10355026_16 Pfam:DUF59 - - - 0.00000000000000001196 85.0
WLSH2_k127_10355026_17 Peptidyl-prolyl cis-trans K01802,K03768,K03775 - 5.2.1.8 0.00000002668 66.0
WLSH2_k127_10355026_2 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 608.0
WLSH2_k127_10355026_3 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 358.0
WLSH2_k127_10355026_4 Uncharacterised ACR, YkgG family COG1556 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 316.0
WLSH2_k127_10355026_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007196 281.0
WLSH2_k127_10355026_6 Belongs to the N(4) N(6)-methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001941 264.0
WLSH2_k127_10355026_7 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000001047 239.0
WLSH2_k127_10355026_8 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000006735 232.0
WLSH2_k127_10355026_9 Membrane - - - 0.0000000000000000000000000000000000000000003554 167.0
WLSH2_k127_10360365_0 Cysteine desulfurase family protein, VC1184 subfamily - - - 0.000000000000000000000000000000000000000000000000000000002004 216.0
WLSH2_k127_10402067_0 DNA polymerase type-B family K02319 - 2.7.7.7 9.26e-261 835.0
WLSH2_k127_10402067_1 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 461.0
WLSH2_k127_10402067_2 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 320.0
WLSH2_k127_10402067_3 Helix-hairpin-helix motif K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004157 242.0
WLSH2_k127_10402067_4 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000001304 237.0
WLSH2_k127_10402067_5 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000002116 175.0
WLSH2_k127_10402067_6 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000002071 114.0
WLSH2_k127_10402067_7 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000001858 79.0
WLSH2_k127_10402067_8 Homeodomain-like domain K06933 - - 0.00000001245 58.0
WLSH2_k127_10510840_0 acetyl-CoA hydrolase transferase - - - 4.027e-216 688.0
WLSH2_k127_10510840_1 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 319.0
WLSH2_k127_10510840_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000168 274.0
WLSH2_k127_10526832_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 420.0
WLSH2_k127_10526832_1 conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003283 265.0
WLSH2_k127_10526832_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000001066 199.0
WLSH2_k127_10526832_3 Rubrerythrin - - - 0.0000001961 63.0
WLSH2_k127_10526832_4 histidine kinase A domain protein - - - 0.000001539 61.0
WLSH2_k127_10547045_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 515.0
WLSH2_k127_10547045_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 364.0
WLSH2_k127_10547045_2 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001371 231.0
WLSH2_k127_10547045_3 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.000000000000000000000000000000000000000000000000000000000000002183 231.0
WLSH2_k127_10547045_4 transcriptional regulators - - - 0.00000000006317 70.0
WLSH2_k127_10770374_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 377.0
WLSH2_k127_10770374_1 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 342.0
WLSH2_k127_10770374_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000001223 238.0
WLSH2_k127_10770374_3 Helix-turn-helix XRE-family like proteins K07108 - - 0.000000000000002213 81.0
WLSH2_k127_10772934_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.955e-269 854.0
WLSH2_k127_10772934_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.773e-263 828.0
WLSH2_k127_10772934_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 490.0
WLSH2_k127_10772934_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000001409 213.0
WLSH2_k127_10772934_4 DnaB-like helicase C terminal domain - - - 0.000000000000000000001781 108.0
WLSH2_k127_10842094_0 Subtilase family K13274,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000007124 261.0
WLSH2_k127_10842094_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000003991 185.0
WLSH2_k127_10887934_0 Peptidase family S51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 326.0
WLSH2_k127_10887934_1 COG1064 Zn-dependent alcohol K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 297.0
WLSH2_k127_10887934_10 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000009101 102.0
WLSH2_k127_10887934_11 - - - - 0.00000000000000000001015 99.0
WLSH2_k127_10887934_12 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000001168 93.0
WLSH2_k127_10887934_13 PFAM PKD domain containing protein K02016,K16925 - - 0.000000000000003148 90.0
WLSH2_k127_10887934_14 transcriptional - - - 0.0001027 53.0
WLSH2_k127_10887934_2 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000001252 221.0
WLSH2_k127_10887934_3 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000007246 220.0
WLSH2_k127_10887934_4 RibD C-terminal domain K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000001157 195.0
WLSH2_k127_10887934_6 Fic/DOC family - - - 0.00000000000000000000000000000000001441 147.0
WLSH2_k127_10887934_7 Flavodoxin - - - 0.000000000000000000000000000000002563 136.0
WLSH2_k127_10887934_9 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000001101 119.0
WLSH2_k127_10889584_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000001143 171.0
WLSH2_k127_10889584_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000496 120.0
WLSH2_k127_10916686_0 Required for chromosome condensation and partitioning K03529 - - 2.166e-257 837.0
WLSH2_k127_10916686_1 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 480.0
WLSH2_k127_10916686_10 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 295.0
WLSH2_k127_10916686_11 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008602 264.0
WLSH2_k127_10916686_12 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000009437 253.0
WLSH2_k127_10916686_13 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000002543 227.0
WLSH2_k127_10916686_14 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000001 212.0
WLSH2_k127_10916686_15 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000006803 208.0
WLSH2_k127_10916686_16 and related - - - 0.00000000000000000000000000000000000000000000000000005554 200.0
WLSH2_k127_10916686_17 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000007842 180.0
WLSH2_k127_10916686_18 chromosome segregation and condensation protein ScpA K05896 - - 0.0000000000000000000000000000000000000000000000002328 196.0
WLSH2_k127_10916686_19 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000001002 183.0
WLSH2_k127_10916686_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 462.0
WLSH2_k127_10916686_20 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.000000000000000000000000000000000000000000006775 169.0
WLSH2_k127_10916686_21 - - - - 0.000000000000000000000000000000000000000002581 160.0
WLSH2_k127_10916686_22 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000004618 151.0
WLSH2_k127_10916686_23 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000006008 158.0
WLSH2_k127_10916686_24 TIGRFAM segregation and condensation protein B K06024 - - 0.000000000000000000000000000005455 130.0
WLSH2_k127_10916686_25 Thiamine-binding protein - - - 0.00000000000000000000000001474 113.0
WLSH2_k127_10916686_26 Pkd domain containing protein - - - 0.000000000000000000000006578 118.0
WLSH2_k127_10916686_27 snRNP Sm proteins K04796 - - 0.0000000000000000000000356 100.0
WLSH2_k127_10916686_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 428.0
WLSH2_k127_10916686_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 397.0
WLSH2_k127_10916686_5 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 377.0
WLSH2_k127_10916686_6 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 349.0
WLSH2_k127_10916686_7 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 361.0
WLSH2_k127_10916686_8 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 343.0
WLSH2_k127_10916686_9 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 305.0
WLSH2_k127_10939867_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.077e-281 899.0
WLSH2_k127_10939867_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 468.0
WLSH2_k127_10939867_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 327.0
WLSH2_k127_10939867_3 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001228 286.0
WLSH2_k127_10939867_4 Peptidase family M28 K01439 - 3.5.1.18 0.00000000000000000000000000000000001405 152.0
WLSH2_k127_10939867_5 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000000006995 107.0
WLSH2_k127_10939867_6 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000001818 103.0
WLSH2_k127_10939867_7 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000000008291 102.0
WLSH2_k127_10939867_8 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000006771 88.0
WLSH2_k127_10939867_9 - - - - 0.000000000000004366 76.0
WLSH2_k127_10982058_0 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000034 216.0
WLSH2_k127_10982058_1 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000005026 168.0
WLSH2_k127_10982058_2 PFAM Mg2 transporter protein CorA family protein K03284 - - 0.000000000000000000000000000000000000001244 160.0
WLSH2_k127_11115268_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.033e-270 850.0
WLSH2_k127_11115268_1 reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000007918 217.0
WLSH2_k127_11115268_2 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000001775 121.0
WLSH2_k127_1114282_0 carbon-monoxide dehydrogenase catalytic subunit K00198 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 400.0
WLSH2_k127_1114282_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 307.0
WLSH2_k127_1114282_2 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000003345 235.0
WLSH2_k127_1114282_3 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000002217 219.0
WLSH2_k127_1114282_4 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000006513 111.0
WLSH2_k127_1114282_5 PFAM amino acid-binding ACT domain protein - - - 0.000004427 54.0
WLSH2_k127_11193061_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000001238 254.0
WLSH2_k127_11193061_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000151 188.0
WLSH2_k127_11193061_2 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0000000000000000000000000000000001085 135.0
WLSH2_k127_11216258_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 417.0
WLSH2_k127_11216258_1 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 407.0
WLSH2_k127_11216258_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000002856 194.0
WLSH2_k127_11216258_11 Calcineurin-like phosphoesterase superfamily domain K06953 - - 0.00000000000000000000000000000000000000000000000003926 190.0
WLSH2_k127_11216258_12 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000002343 196.0
WLSH2_k127_11216258_13 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000008248 145.0
WLSH2_k127_11216258_14 Uncharacterized ArCR, COG1888 K09732 - - 0.0000000000000000000000000004604 115.0
WLSH2_k127_11216258_15 binds to the 23S rRNA K02921 - - 0.00000000000000033 82.0
WLSH2_k127_11216258_16 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.000000000000002603 78.0
WLSH2_k127_11216258_17 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000002485 71.0
WLSH2_k127_11216258_18 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.000000000005709 66.0
WLSH2_k127_11216258_19 Transcription factor Pcc1 K09741 - - 0.00001345 52.0
WLSH2_k127_11216258_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 398.0
WLSH2_k127_11216258_20 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0001622 48.0
WLSH2_k127_11216258_21 exodeoxyribonuclease I activity - - - 0.0001798 53.0
WLSH2_k127_11216258_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 393.0
WLSH2_k127_11216258_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 328.0
WLSH2_k127_11216258_5 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 326.0
WLSH2_k127_11216258_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 304.0
WLSH2_k127_11216258_7 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 299.0
WLSH2_k127_11216258_8 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 301.0
WLSH2_k127_11216258_9 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000242 262.0
WLSH2_k127_11229976_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 2.5e-241 758.0
WLSH2_k127_11229976_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 3.61e-221 709.0
WLSH2_k127_11229976_10 Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000000000000001402 144.0
WLSH2_k127_11229976_11 Response regulator receiver domain - - - 0.000000000000000001006 93.0
WLSH2_k127_11229976_12 Roadblock LC7 family protein K07131 - - 0.0000000000007358 74.0
WLSH2_k127_11229976_2 oligoendopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 413.0
WLSH2_k127_11229976_3 ATPases associated with a variety of cellular activities K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 323.0
WLSH2_k127_11229976_4 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 303.0
WLSH2_k127_11229976_5 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001705 292.0
WLSH2_k127_11229976_6 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000004457 218.0
WLSH2_k127_11229976_7 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000003816 207.0
WLSH2_k127_11229976_8 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000004518 197.0
WLSH2_k127_11229976_9 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000000000000001399 181.0
WLSH2_k127_11261510_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 493.0
WLSH2_k127_11261510_1 Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 385.0
WLSH2_k127_11261510_2 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 294.0
WLSH2_k127_11261510_3 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.0000000000000000000000000000000000000000000000001896 189.0
WLSH2_k127_11261510_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000002665 68.0
WLSH2_k127_11261510_5 Acetyltransferase (GNAT) family - - - 0.00000001159 64.0
WLSH2_k127_11290772_0 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000429 261.0
WLSH2_k127_11290772_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000001816 213.0
WLSH2_k127_11290772_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000001032 170.0
WLSH2_k127_11290772_3 Protein of unknown function DUF134 K06933 - - 0.0000000000000000001125 91.0
WLSH2_k127_11290772_4 Family of unknown function (DUF5320) - - - 0.000000000000000000797 90.0
WLSH2_k127_11290772_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000294 51.0
WLSH2_k127_11347415_0 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 404.0
WLSH2_k127_11347415_1 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 320.0
WLSH2_k127_11347415_10 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000004166 112.0
WLSH2_k127_11347415_11 4Fe-4S dicluster domain - - - 0.000000000000000008798 87.0
WLSH2_k127_11347415_12 ABC-2 family transporter protein K01992 - - 0.00000000000000005526 95.0
WLSH2_k127_11347415_13 protein involved in the oxidation of intracellular sulfur K07236 - - 0.0000000000000002096 83.0
WLSH2_k127_11347415_14 - K21029 - 2.7.7.80 0.00002823 53.0
WLSH2_k127_11347415_2 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001137 286.0
WLSH2_k127_11347415_3 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000001845 204.0
WLSH2_k127_11347415_4 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000000000000023 200.0
WLSH2_k127_11347415_5 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000001113 168.0
WLSH2_k127_11347415_6 AAA domain - - - 0.000000000000000000000000000000000000000000005226 169.0
WLSH2_k127_11347415_7 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000575 166.0
WLSH2_k127_11347415_8 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000005815 116.0
WLSH2_k127_11347415_9 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000008242 116.0
WLSH2_k127_11370442_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.64e-225 711.0
WLSH2_k127_11370442_1 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 484.0
WLSH2_k127_11370442_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002335 269.0
WLSH2_k127_11370442_3 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000001916 203.0
WLSH2_k127_11391158_0 CobW/HypB/UreG, nucleotide-binding domain - - - 9.942e-194 618.0
WLSH2_k127_11391158_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 570.0
WLSH2_k127_11391158_10 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000002643 264.0
WLSH2_k127_11391158_11 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000001067 253.0
WLSH2_k127_11391158_12 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000002195 227.0
WLSH2_k127_11391158_13 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000004331 184.0
WLSH2_k127_11391158_14 amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000005801 178.0
WLSH2_k127_11391158_15 Pfam:Methyltransf_26 K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.000000000000000000000000000000000000000000001703 177.0
WLSH2_k127_11391158_16 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.00000000000000000000000000000000000000000001253 177.0
WLSH2_k127_11391158_17 PFAM GvpD gas vesicle - - - 0.00000000000000000000000000000000000000000001691 181.0
WLSH2_k127_11391158_18 protein conserved in bacteria - - - 0.000000000000000000000000000000000000001237 167.0
WLSH2_k127_11391158_19 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000001563 115.0
WLSH2_k127_11391158_2 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 464.0
WLSH2_k127_11391158_20 - - - - 0.0000000000000000000518 94.0
WLSH2_k127_11391158_21 transcriptional regulators - - - 0.00000000000006308 79.0
WLSH2_k127_11391158_22 ribosomal small subunit binding - - - 0.0000000003467 70.0
WLSH2_k127_11391158_3 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 460.0
WLSH2_k127_11391158_4 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 452.0
WLSH2_k127_11391158_5 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 411.0
WLSH2_k127_11391158_6 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 388.0
WLSH2_k127_11391158_7 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 353.0
WLSH2_k127_11391158_8 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 305.0
WLSH2_k127_11391158_9 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 314.0
WLSH2_k127_1191247_0 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 378.0
WLSH2_k127_1191247_1 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 318.0
WLSH2_k127_1191247_10 PFAM glutaredoxin - - - 0.0000000000000000001405 91.0
WLSH2_k127_1191247_11 SCP-2 sterol transfer family - - - 0.000000000001688 79.0
WLSH2_k127_1191247_12 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000001669 58.0
WLSH2_k127_1191247_13 Tetratricopeptide TPR_2 repeat protein - - - 0.00004045 52.0
WLSH2_k127_1191247_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000008802 191.0
WLSH2_k127_1191247_3 PIN domain - - - 0.000000000000000000000000000000000000000000000003494 190.0
WLSH2_k127_1191247_4 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000000000000000000000001798 164.0
WLSH2_k127_1191247_5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000002615 169.0
WLSH2_k127_1191247_7 Ribosomal RNA adenine dimethylase - - - 0.000000000000000000000000005064 118.0
WLSH2_k127_1191247_8 - - - - 0.000000000000000000000004865 108.0
WLSH2_k127_1191247_9 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000000982 104.0
WLSH2_k127_131918_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 378.0
WLSH2_k127_131918_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 373.0
WLSH2_k127_131918_10 Protein of unknown function (DUF1614) - - - 0.000000000000000000001076 104.0
WLSH2_k127_131918_11 PFAM CBS domain - - - 0.0000000000000008338 83.0
WLSH2_k127_131918_12 Major facilitator Superfamily - - - 0.000000000000006049 87.0
WLSH2_k127_131918_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000001879 70.0
WLSH2_k127_131918_14 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000003037 76.0
WLSH2_k127_131918_15 Small-conductance mechanosensitive channel - - - 0.00000005622 61.0
WLSH2_k127_131918_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 354.0
WLSH2_k127_131918_3 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 313.0
WLSH2_k127_131918_4 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000001988 189.0
WLSH2_k127_131918_5 Saccharopine dehydrogenase K00290,K19064 - 1.4.1.18,1.5.1.7 0.000000000000000000000000000000000000002839 161.0
WLSH2_k127_131918_6 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000004487 159.0
WLSH2_k127_131918_7 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000007585 146.0
WLSH2_k127_131918_8 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000003901 130.0
WLSH2_k127_131918_9 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000005572 124.0
WLSH2_k127_1366090_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 501.0
WLSH2_k127_1366090_1 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 497.0
WLSH2_k127_1366090_2 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 498.0
WLSH2_k127_1366090_3 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000034 286.0
WLSH2_k127_1366090_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000004813 163.0
WLSH2_k127_1366090_5 Helix-turn-helix XRE-family like proteins K07731 - - 0.000000000000000000000000000004891 120.0
WLSH2_k127_1366090_6 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000002586 73.0
WLSH2_k127_1442387_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 509.0
WLSH2_k127_1442387_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 324.0
WLSH2_k127_1442387_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000001047 167.0
WLSH2_k127_1442387_11 - - - - 0.000000000000000000000000000000006487 140.0
WLSH2_k127_1442387_12 - - - - 0.00000000000000000001554 95.0
WLSH2_k127_1442387_13 PFAM band 7 protein - - - 0.00000000000000001711 93.0
WLSH2_k127_1442387_14 Clostripain family - - - 0.00000000000000007138 94.0
WLSH2_k127_1442387_15 PFAM Methyltransferase domain - - - 0.000000000001813 79.0
WLSH2_k127_1442387_16 Urocanase C-terminal domain K01712 - 4.2.1.49 0.000000002824 57.0
WLSH2_k127_1442387_17 - - - - 0.0000009867 61.0
WLSH2_k127_1442387_18 Acetyltransferase (GNAT) domain - - - 0.0001343 50.0
WLSH2_k127_1442387_19 transcriptional - - - 0.0003696 50.0
WLSH2_k127_1442387_2 transmembrane transport K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 325.0
WLSH2_k127_1442387_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 312.0
WLSH2_k127_1442387_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 289.0
WLSH2_k127_1442387_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001548 286.0
WLSH2_k127_1442387_6 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002023 272.0
WLSH2_k127_1442387_7 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003562 285.0
WLSH2_k127_1442387_8 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000003968 242.0
WLSH2_k127_1442387_9 - - - - 0.000000000000000000000000000000000000000005877 168.0
WLSH2_k127_1634966_0 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000055 164.0
WLSH2_k127_1634966_1 hydrolase (HAD superfamily) K07025 - - 0.0000000000000000000000000000000000000000183 162.0
WLSH2_k127_1634966_2 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000196 134.0
WLSH2_k127_1634966_3 FG-GAP repeat - - - 0.00000000000000000002093 108.0
WLSH2_k127_1634966_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000004127 74.0
WLSH2_k127_1634966_5 OmpA family K02557,K03286 - - 0.0000001342 66.0
WLSH2_k127_1645493_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 511.0
WLSH2_k127_1645493_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 398.0
WLSH2_k127_1645493_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006931 281.0
WLSH2_k127_1645493_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000006926 228.0
WLSH2_k127_1645493_4 4Fe-4S dicluster domain K00338,K14121,K22164,K22176 - 1.1.98.4,1.5.98.3,1.6.5.3 0.00000000000000000000000000000000001546 147.0
WLSH2_k127_1645493_5 NADH ubiquinone oxidoreductase 27 kD subunit K00332,K22160 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000001687 121.0
WLSH2_k127_1645493_6 NADH ubiquinone oxidoreductase subunit 3 (Chain a) K00330,K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3,1.6.5.3 0.0000000000000000000000177 104.0
WLSH2_k127_1645493_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000007055 76.0
WLSH2_k127_1645493_8 helix_turn_helix ASNC type - - - 0.000000001873 69.0
WLSH2_k127_1645493_9 NADH ubiquinone oxidoreductase subunit 6 (chain J) K00339,K22165 - 1.5.98.3,1.6.5.3 0.0000025 55.0
WLSH2_k127_2045332_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1068.0
WLSH2_k127_2045332_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 2.008e-243 772.0
WLSH2_k127_2045332_10 Peptidase dimerisation domain K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 351.0
WLSH2_k127_2045332_11 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 347.0
WLSH2_k127_2045332_12 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 344.0
WLSH2_k127_2045332_13 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 327.0
WLSH2_k127_2045332_14 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 293.0
WLSH2_k127_2045332_15 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002856 279.0
WLSH2_k127_2045332_16 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000002491 258.0
WLSH2_k127_2045332_17 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000001723 228.0
WLSH2_k127_2045332_18 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000001526 221.0
WLSH2_k127_2045332_19 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000000000000000000000000000000000005724 213.0
WLSH2_k127_2045332_2 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 596.0
WLSH2_k127_2045332_20 PFAM Major Facilitator Superfamily K19576 - - 0.000000000000000000000000000000000000000000000000000006049 204.0
WLSH2_k127_2045332_21 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000000005756 186.0
WLSH2_k127_2045332_22 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000001766 184.0
WLSH2_k127_2045332_23 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000538 177.0
WLSH2_k127_2045332_24 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000000001421 121.0
WLSH2_k127_2045332_25 EamA-like transporter family - - - 0.000000000000000001785 96.0
WLSH2_k127_2045332_26 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000006561 85.0
WLSH2_k127_2045332_27 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000000000001726 86.0
WLSH2_k127_2045332_28 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000002001 85.0
WLSH2_k127_2045332_29 Helix-turn-helix domain - - - 0.0000000000002041 78.0
WLSH2_k127_2045332_3 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 538.0
WLSH2_k127_2045332_30 - - - - 0.000000000006979 68.0
WLSH2_k127_2045332_31 Lrp/AsnC ligand binding domain - - - 0.0001765 46.0
WLSH2_k127_2045332_4 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 511.0
WLSH2_k127_2045332_5 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 484.0
WLSH2_k127_2045332_6 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 437.0
WLSH2_k127_2045332_7 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 386.0
WLSH2_k127_2045332_8 ABC transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 362.0
WLSH2_k127_2045332_9 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 359.0
WLSH2_k127_2134298_0 cobalamin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 542.0
WLSH2_k127_2134298_1 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 488.0
WLSH2_k127_2134298_10 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000005384 124.0
WLSH2_k127_2134298_11 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000003251 117.0
WLSH2_k127_2134298_12 Clostripain family - - - 0.00000000000000000001261 105.0
WLSH2_k127_2134298_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000003765 93.0
WLSH2_k127_2134298_14 - - - - 0.0000000000006781 78.0
WLSH2_k127_2134298_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000006781 78.0
WLSH2_k127_2134298_16 membrane - - - 0.00005061 52.0
WLSH2_k127_2134298_2 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 417.0
WLSH2_k127_2134298_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 299.0
WLSH2_k127_2134298_4 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000556 270.0
WLSH2_k127_2134298_5 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000005555 230.0
WLSH2_k127_2134298_6 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000003163 192.0
WLSH2_k127_2134298_7 - - - - 0.0000000000000000000000000000000000000000000000001458 183.0
WLSH2_k127_2134298_8 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000185 179.0
WLSH2_k127_2134298_9 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000003969 138.0
WLSH2_k127_2329338_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.87e-248 785.0
WLSH2_k127_2329338_1 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 1.039e-216 704.0
WLSH2_k127_2329338_10 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000003297 205.0
WLSH2_k127_2329338_11 lactate oxidation K16950 - - 0.0000000000000000000000000000000000000004098 160.0
WLSH2_k127_2329338_12 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000000000000000007456 128.0
WLSH2_k127_2329338_13 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000001504 119.0
WLSH2_k127_2329338_14 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000001797 85.0
WLSH2_k127_2329338_2 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 1.314e-212 675.0
WLSH2_k127_2329338_3 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 495.0
WLSH2_k127_2329338_4 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 390.0
WLSH2_k127_2329338_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 377.0
WLSH2_k127_2329338_6 COG0477 Permeases of the major facilitator superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 307.0
WLSH2_k127_2329338_7 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002497 244.0
WLSH2_k127_2329338_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000006059 250.0
WLSH2_k127_2329338_9 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000008483 193.0
WLSH2_k127_234191_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1746.0
WLSH2_k127_234191_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1297.0
WLSH2_k127_234191_10 RNA-binding protein of the translin family K07477 - - 0.00000000000000000000000000000000000000000000003938 177.0
WLSH2_k127_234191_11 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.000000000000000000000000000000000000000188 156.0
WLSH2_k127_234191_12 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000001722 123.0
WLSH2_k127_234191_13 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000006356 100.0
WLSH2_k127_234191_14 PFAM Rhomboid family protein K07059 - - 0.00000000000000000004704 102.0
WLSH2_k127_234191_15 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.00000000000000001959 94.0
WLSH2_k127_234191_16 PFAM beta-lactamase domain protein - - - 0.00000000000003551 84.0
WLSH2_k127_234191_17 - - - - 0.0000001907 63.0
WLSH2_k127_234191_2 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 2.02e-257 870.0
WLSH2_k127_234191_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 605.0
WLSH2_k127_234191_4 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 480.0
WLSH2_k127_234191_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 434.0
WLSH2_k127_234191_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 418.0
WLSH2_k127_234191_7 4Fe-4S single cluster domain K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 374.0
WLSH2_k127_234191_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000006311 257.0
WLSH2_k127_234191_9 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000000000000000000000002836 202.0
WLSH2_k127_2393046_0 Citrate transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 481.0
WLSH2_k127_2393046_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 364.0
WLSH2_k127_2393046_2 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.000000000000000000000000000000000000000000000000003534 203.0
WLSH2_k127_2393046_3 Ferrous iron transport B domain protein K04759 - - 0.00000000000000005552 83.0
WLSH2_k127_2393046_4 Belongs to the peptidase S8 family K01361,K08652,K14647 GO:0005575,GO:0005576 3.4.21.110,3.4.21.96 0.000107 55.0
WLSH2_k127_2400443_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 589.0
WLSH2_k127_2400443_1 Arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 377.0
WLSH2_k127_2400443_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 359.0
WLSH2_k127_2400443_3 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000008986 225.0
WLSH2_k127_2400443_4 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000001824 197.0
WLSH2_k127_2400443_5 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000004809 141.0
WLSH2_k127_2400443_6 4Fe-4S binding domain - - - 0.0000000000000000000000000000000001804 138.0
WLSH2_k127_2400443_7 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000000000000000000006143 108.0
WLSH2_k127_2400443_8 Roadblock LC7 family protein K07131 - - 0.0000000000000003995 83.0
WLSH2_k127_2477495_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 498.0
WLSH2_k127_2477495_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 480.0
WLSH2_k127_2477495_2 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000002759 107.0
WLSH2_k127_2549594_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 439.0
WLSH2_k127_2549594_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 348.0
WLSH2_k127_2549594_2 methanogenesis marker protein 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 342.0
WLSH2_k127_2549594_3 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001 248.0
WLSH2_k127_2549594_4 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000000000001072 229.0
WLSH2_k127_2549594_5 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000000000000000000002859 161.0
WLSH2_k127_2549594_6 Protein of unknown function (DUF2797) - - - 0.00000000000001112 84.0
WLSH2_k127_2549594_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000439 46.0
WLSH2_k127_2587972_0 Cell division protein 48, CDC48, domain 2 K13525 - - 5.704e-274 861.0
WLSH2_k127_2587972_1 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 566.0
WLSH2_k127_2587972_10 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009377 242.0
WLSH2_k127_2587972_11 HisG, C-terminal domain K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000001751 222.0
WLSH2_k127_2587972_12 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000001405 213.0
WLSH2_k127_2587972_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000002625 208.0
WLSH2_k127_2587972_14 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000003269 211.0
WLSH2_k127_2587972_15 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000008624 181.0
WLSH2_k127_2587972_16 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000001595 180.0
WLSH2_k127_2587972_17 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000216 185.0
WLSH2_k127_2587972_18 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000003569 194.0
WLSH2_k127_2587972_19 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000006431 174.0
WLSH2_k127_2587972_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 520.0
WLSH2_k127_2587972_20 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000000007439 174.0
WLSH2_k127_2587972_21 Sodium hydrogen exchanger K11105 - - 0.0000000000000000000000000000000000000000008653 173.0
WLSH2_k127_2587972_22 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000007899 157.0
WLSH2_k127_2587972_23 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000005966 159.0
WLSH2_k127_2587972_24 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000000002195 149.0
WLSH2_k127_2587972_25 - - - - 0.000000000000000000000000000003044 136.0
WLSH2_k127_2587972_26 - - - - 0.000000000000000000000000001735 122.0
WLSH2_k127_2587972_27 PRC-barrel domain - - - 0.0000000000000000000000002149 107.0
WLSH2_k127_2587972_28 protein conserved in archaea - - - 0.000000000000000000000001316 106.0
WLSH2_k127_2587972_29 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000001382 109.0
WLSH2_k127_2587972_3 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 452.0
WLSH2_k127_2587972_30 Response regulator receiver domain - - - 0.000000000000000001979 91.0
WLSH2_k127_2587972_31 response to oxidative stress K04063 - - 0.0000000000000003983 85.0
WLSH2_k127_2587972_32 Tetratricopeptide repeat - - - 0.00000000000000356 89.0
WLSH2_k127_2587972_33 PRC-barrel domain protein - - - 0.00000000000008637 76.0
WLSH2_k127_2587972_34 Glutamine amidotransferases class-II - - - 0.000000000001297 77.0
WLSH2_k127_2587972_35 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000001661 78.0
WLSH2_k127_2587972_36 but it may be involved in stabilization of the trimeric complex - - - 0.0000000001279 63.0
WLSH2_k127_2587972_37 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000006067 65.0
WLSH2_k127_2587972_39 - - - - 0.000002384 55.0
WLSH2_k127_2587972_4 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 359.0
WLSH2_k127_2587972_5 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 342.0
WLSH2_k127_2587972_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 335.0
WLSH2_k127_2587972_7 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 308.0
WLSH2_k127_2587972_8 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003146 285.0
WLSH2_k127_2587972_9 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000722 253.0
WLSH2_k127_2590848_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1166.0
WLSH2_k127_2590848_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.781e-257 802.0
WLSH2_k127_2590848_2 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 312.0
WLSH2_k127_2590848_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.000001504 53.0
WLSH2_k127_259772_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 316.0
WLSH2_k127_259772_1 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000208 263.0
WLSH2_k127_259772_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000006782 181.0
WLSH2_k127_259772_3 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000001634 92.0
WLSH2_k127_2668109_0 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.0000000000000000000000000000000000000000106 175.0
WLSH2_k127_2712962_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 551.0
WLSH2_k127_2712962_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000004624 249.0
WLSH2_k127_2712962_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000000000000000000000000000000000000000000000000000006983 203.0
WLSH2_k127_2712962_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000002169 177.0
WLSH2_k127_2712962_4 - - - - 0.0000000000000000000004125 108.0
WLSH2_k127_2712962_5 Sulfite exporter TauE/SafE K07090 - - 0.0000000001839 71.0
WLSH2_k127_2712962_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0031410,GO:0031982,GO:0043226,GO:0043227,GO:0043229,GO:0044424,GO:0044444,GO:0044464,GO:0097708 - 0.0000000002333 74.0
WLSH2_k127_2712962_7 Dinitrogenase iron-molybdenum cofactor - - - 0.00004061 51.0
WLSH2_k127_2793763_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 416.0
WLSH2_k127_2793763_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 388.0
WLSH2_k127_2793763_10 - - - - 0.00003284 48.0
WLSH2_k127_2793763_2 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000221 285.0
WLSH2_k127_2793763_3 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004821 280.0
WLSH2_k127_2793763_4 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005768 263.0
WLSH2_k127_2793763_5 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001402 240.0
WLSH2_k127_2793763_6 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000000000000000000095 123.0
WLSH2_k127_2793763_7 lipase activity K01083,K11018,K12686,K15349,K21831 GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 3.1.3.8 0.00000000000000000000003652 115.0
WLSH2_k127_2793763_8 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000000000009482 102.0
WLSH2_k127_2793763_9 - - - - 0.000000000002059 73.0
WLSH2_k127_3093090_0 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 356.0
WLSH2_k127_3093090_1 Transcriptional regulator K07730 - - 0.000000000000000001033 96.0
WLSH2_k127_3093090_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000001933 79.0
WLSH2_k127_3093090_3 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000001273 55.0
WLSH2_k127_3140949_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 368.0
WLSH2_k127_3140949_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000004446 195.0
WLSH2_k127_3140949_2 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000002441 157.0
WLSH2_k127_3140949_3 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000001426 144.0
WLSH2_k127_3140949_4 spore germination - - - 0.0000000000000000004382 98.0
WLSH2_k127_3156808_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 415.0
WLSH2_k127_3156808_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000002828 271.0
WLSH2_k127_3156808_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000016 190.0
WLSH2_k127_3156808_3 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000008977 143.0
WLSH2_k127_3156808_4 ACT domain protein - - - 0.0000000000000006848 82.0
WLSH2_k127_3156808_5 Belongs to the catalase family K03781 - 1.11.1.6 0.00000000003867 63.0
WLSH2_k127_3156808_6 - - - - 0.00000004095 58.0
WLSH2_k127_3219814_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1115.0
WLSH2_k127_3219814_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1089.0
WLSH2_k127_3219814_2 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 495.0
WLSH2_k127_3219814_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 455.0
WLSH2_k127_3219814_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 363.0
WLSH2_k127_3219814_5 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000005793 230.0
WLSH2_k127_3219814_6 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000002645 212.0
WLSH2_k127_3219814_7 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000007203 187.0
WLSH2_k127_3219814_8 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000611 119.0
WLSH2_k127_3219814_9 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000005228 63.0
WLSH2_k127_3262529_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 3.04e-238 763.0
WLSH2_k127_3262529_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000007528 243.0
WLSH2_k127_3262529_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000001155 244.0
WLSH2_k127_3262529_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000001809 213.0
WLSH2_k127_3262529_4 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000003278 205.0
WLSH2_k127_3262529_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000001014 189.0
WLSH2_k127_3262529_6 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000001557 160.0
WLSH2_k127_3262529_7 VIT family - - - 0.0000000000000000000000000000000000001602 148.0
WLSH2_k127_3262529_8 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000004303 111.0
WLSH2_k127_3262529_9 cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000004967 81.0
WLSH2_k127_3276631_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.983e-197 629.0
WLSH2_k127_3276631_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000000000000003358 223.0
WLSH2_k127_3276631_10 diguanylate cyclase - - - 0.00001247 59.0
WLSH2_k127_3276631_2 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000003988 213.0
WLSH2_k127_3276631_3 Phenazine biosynthesis protein phzf family - - - 0.0000000000000000000000000000000000000000000005801 178.0
WLSH2_k127_3276631_4 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000003159 173.0
WLSH2_k127_3276631_5 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.00000000000000000000000000000000422 136.0
WLSH2_k127_3276631_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000005346 133.0
WLSH2_k127_3276631_7 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000003769 114.0
WLSH2_k127_3276631_8 Polymer-forming cytoskeletal - - - 0.000000000004629 68.0
WLSH2_k127_3276631_9 Bacterial regulatory protein, Fis family K02584 - - 0.000005461 61.0
WLSH2_k127_3415470_0 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 406.0
WLSH2_k127_3415470_1 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 354.0
WLSH2_k127_3415470_2 exonuclease K07502 - - 0.0000000000000000000000000000000000000000000000000001277 195.0
WLSH2_k127_3415470_3 Calcineurin-like phosphoesterase superfamily domain K06953 - - 0.00000000000000000000000000000000000001095 155.0
WLSH2_k127_3415470_4 Small-conductance mechanosensitive channel - - - 0.000000000004557 69.0
WLSH2_k127_3415470_5 Zn-finger in Ran binding protein and others - - - 0.0002769 49.0
WLSH2_k127_3831185_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.712e-308 966.0
WLSH2_k127_3831185_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001407 277.0
WLSH2_k127_3831185_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000223 240.0
WLSH2_k127_3831185_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000002407 193.0
WLSH2_k127_3831185_4 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000808 90.0
WLSH2_k127_3853994_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 533.0
WLSH2_k127_3853994_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 521.0
WLSH2_k127_3853994_2 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000001746 271.0
WLSH2_k127_3853994_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000004284 65.0
WLSH2_k127_3871757_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 315.0
WLSH2_k127_3871757_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000004068 270.0
WLSH2_k127_3871757_10 FHA domain - - - 0.0000009457 60.0
WLSH2_k127_3871757_2 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007773 260.0
WLSH2_k127_3871757_3 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000003786 243.0
WLSH2_k127_3871757_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000001866 212.0
WLSH2_k127_3871757_5 DNA repair and recombination protein RadB K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000003058 192.0
WLSH2_k127_3871757_6 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000001371 187.0
WLSH2_k127_3871757_7 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.0000000000000000000000000000000000000000000002798 174.0
WLSH2_k127_3871757_8 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000000000007928 117.0
WLSH2_k127_3889008_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 418.0
WLSH2_k127_3889008_1 Methyltransferase domain - - - 0.00000000000000003698 91.0
WLSH2_k127_4099606_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 325.0
WLSH2_k127_4099606_1 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000006012 167.0
WLSH2_k127_4099606_2 Ribbon-helix-helix protein, copG family K07722 - - 0.0000000000000000000009614 98.0
WLSH2_k127_4099606_3 Pkd domain containing protein - - - 0.00000000001659 74.0
WLSH2_k127_4100962_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 498.0
WLSH2_k127_4100962_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004541 264.0
WLSH2_k127_4161816_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.052e-225 723.0
WLSH2_k127_4161816_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 488.0
WLSH2_k127_4161816_10 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000002331 245.0
WLSH2_k127_4161816_11 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000008665 217.0
WLSH2_k127_4161816_12 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000006504 184.0
WLSH2_k127_4161816_13 Archaeal holliday junction resolvase (hjc) - - - 0.00000000000000000000000000000000000000000000004313 175.0
WLSH2_k127_4161816_14 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000624 175.0
WLSH2_k127_4161816_15 LysE type translocator - - - 0.00000000000000000000000000000000000000000009324 168.0
WLSH2_k127_4161816_16 Domains REC, HisKA, HATPase_c - - - 0.0000000000000000000000000000000000000000001192 181.0
WLSH2_k127_4161816_17 Oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000005644 155.0
WLSH2_k127_4161816_18 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000000001441 147.0
WLSH2_k127_4161816_19 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.00000000000000000000000000000000001782 142.0
WLSH2_k127_4161816_2 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 480.0
WLSH2_k127_4161816_20 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.000000000000000000000000000008748 121.0
WLSH2_k127_4161816_21 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000155 123.0
WLSH2_k127_4161816_22 PFAM CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000007057 99.0
WLSH2_k127_4161816_23 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000000003467 78.0
WLSH2_k127_4161816_24 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000001099 81.0
WLSH2_k127_4161816_25 EamA-like transporter family - - - 0.00000000000002953 83.0
WLSH2_k127_4161816_26 COG1522 Transcriptional regulators - - - 0.000000000004719 77.0
WLSH2_k127_4161816_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 468.0
WLSH2_k127_4161816_4 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 393.0
WLSH2_k127_4161816_5 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 398.0
WLSH2_k127_4161816_6 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 335.0
WLSH2_k127_4161816_7 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 324.0
WLSH2_k127_4161816_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000002057 273.0
WLSH2_k127_4161816_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001257 251.0
WLSH2_k127_4233972_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000001629 250.0
WLSH2_k127_4233972_1 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.000000000000000000000000000000000000000000000000000008026 199.0
WLSH2_k127_4233972_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000003472 154.0
WLSH2_k127_4233972_3 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000001051 115.0
WLSH2_k127_4305945_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 399.0
WLSH2_k127_4305945_1 PFAM AIR synthase related protein K07123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003935 287.0
WLSH2_k127_4305945_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004414 258.0
WLSH2_k127_4305945_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000005735 260.0
WLSH2_k127_4305945_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000007153 243.0
WLSH2_k127_4305945_5 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000001411 211.0
WLSH2_k127_4305945_6 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000000000003858 181.0
WLSH2_k127_4305945_7 - - - - 0.000000000000000000000000000000001805 136.0
WLSH2_k127_4305945_8 - - - - 0.0000000000000000000000000001753 121.0
WLSH2_k127_4305945_9 - K00960 - 2.7.7.6 0.0000000000000006159 78.0
WLSH2_k127_4306025_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 525.0
WLSH2_k127_4306025_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 317.0
WLSH2_k127_4306025_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008308 295.0
WLSH2_k127_4306025_3 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004465 269.0
WLSH2_k127_4306025_4 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000002341 202.0
WLSH2_k127_4306025_5 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000005421 164.0
WLSH2_k127_4306025_6 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000005996 139.0
WLSH2_k127_4306025_7 - - - - 0.0000000000008425 72.0
WLSH2_k127_4318676_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 3.402e-221 699.0
WLSH2_k127_4318676_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 569.0
WLSH2_k127_4318676_10 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000001129 244.0
WLSH2_k127_4318676_11 Enoyl-(Acyl carrier protein) reductase K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000194 236.0
WLSH2_k127_4318676_12 Domain of unknown function (DUF389) - - - 0.0000000000000000000000000000000000000000000000008686 186.0
WLSH2_k127_4318676_13 Flavodoxin - - - 0.00000000000000000000000000000000000000001623 157.0
WLSH2_k127_4318676_14 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000002697 153.0
WLSH2_k127_4318676_15 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000004879 159.0
WLSH2_k127_4318676_16 myo-inosose-2 dehydratase activity K10709 - - 0.0000000000000000000000000000000002022 143.0
WLSH2_k127_4318676_17 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.000000000000000000000000000000000861 146.0
WLSH2_k127_4318676_18 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840 - 0.000000000000000000000000000000009568 130.0
WLSH2_k127_4318676_19 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000000000000000000000000000605 134.0
WLSH2_k127_4318676_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 379.0
WLSH2_k127_4318676_20 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.0000000000000000000000000003804 129.0
WLSH2_k127_4318676_21 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000004004 108.0
WLSH2_k127_4318676_22 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.000000000000000000000007156 109.0
WLSH2_k127_4318676_23 Rubredoxin - - - 0.000000000000000000000439 97.0
WLSH2_k127_4318676_24 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000005522 101.0
WLSH2_k127_4318676_25 COG0521 Molybdopterin biosynthesis enzymes K03638 - 2.7.7.75 0.000000000000000000001594 101.0
WLSH2_k127_4318676_26 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000001367 97.0
WLSH2_k127_4318676_27 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000001764 94.0
WLSH2_k127_4318676_28 acetyltransferase - - - 0.000000000000001386 88.0
WLSH2_k127_4318676_29 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.000000000000003777 75.0
WLSH2_k127_4318676_3 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 365.0
WLSH2_k127_4318676_30 Acetyltransferase (GNAT) domain - - - 0.000000000000006002 81.0
WLSH2_k127_4318676_31 PFAM CoA-binding domain protein - - - 0.00000000001693 70.0
WLSH2_k127_4318676_32 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.0000000001138 72.0
WLSH2_k127_4318676_33 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000001188 70.0
WLSH2_k127_4318676_34 Acetyltransferase (GNAT) domain - - - 0.000000004813 68.0
WLSH2_k127_4318676_35 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.00000001015 64.0
WLSH2_k127_4318676_36 Rubrerythrin - - - 0.00000001124 63.0
WLSH2_k127_4318676_37 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000001571 55.0
WLSH2_k127_4318676_38 COG1335 Amidases related to nicotinamidase - - - 0.00002201 54.0
WLSH2_k127_4318676_39 Serine threonine-protein kinase K04424 - 2.7.11.25 0.0009201 45.0
WLSH2_k127_4318676_4 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 334.0
WLSH2_k127_4318676_5 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 305.0
WLSH2_k127_4318676_6 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 291.0
WLSH2_k127_4318676_7 arginine decarboxylase activity K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001091 258.0
WLSH2_k127_4318676_8 COG COG0714 MoxR-like ATPases General function prediction only - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001528 274.0
WLSH2_k127_4318676_9 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006593 248.0
WLSH2_k127_442449_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 554.0
WLSH2_k127_442449_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 380.0
WLSH2_k127_442449_10 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.000000000000000000000000000000000003831 157.0
WLSH2_k127_442449_11 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000258 138.0
WLSH2_k127_442449_12 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000042 135.0
WLSH2_k127_442449_13 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000004435 125.0
WLSH2_k127_442449_14 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000001329 117.0
WLSH2_k127_442449_15 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001682 86.0
WLSH2_k127_442449_16 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000003197 92.0
WLSH2_k127_442449_17 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000006467 72.0
WLSH2_k127_442449_18 - - - - 0.0000000007928 71.0
WLSH2_k127_442449_19 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000004704 52.0
WLSH2_k127_442449_2 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 358.0
WLSH2_k127_442449_3 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 294.0
WLSH2_k127_442449_4 translation initiation factor 2 subunit alpha K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 290.0
WLSH2_k127_442449_5 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000189 272.0
WLSH2_k127_442449_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000287 236.0
WLSH2_k127_442449_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000001507 224.0
WLSH2_k127_442449_8 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000004178 220.0
WLSH2_k127_442449_9 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000245 194.0
WLSH2_k127_4468990_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 439.0
WLSH2_k127_4468990_1 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000213 181.0
WLSH2_k127_4468990_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000001086 100.0
WLSH2_k127_4486679_0 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 325.0
WLSH2_k127_4486679_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001106 201.0
WLSH2_k127_4486679_10 ribosomal protein S14 K02954 - - 0.000000000000000004445 91.0
WLSH2_k127_4486679_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001303 200.0
WLSH2_k127_4486679_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000005967 194.0
WLSH2_k127_4486679_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000003179 179.0
WLSH2_k127_4486679_5 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000006547 183.0
WLSH2_k127_4486679_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001387 181.0
WLSH2_k127_4486679_7 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000006234 167.0
WLSH2_k127_4486679_8 Ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000007896 161.0
WLSH2_k127_4486679_9 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000008747 154.0
WLSH2_k127_4557726_0 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000001459 213.0
WLSH2_k127_4557726_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000008005 120.0
WLSH2_k127_4557726_2 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000002416 83.0
WLSH2_k127_4557726_3 40-residue YVTN family beta-propeller repeat - - - 0.0006281 49.0
WLSH2_k127_4584314_0 KH domain K07041 - - 1.069e-264 829.0
WLSH2_k127_4584314_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 361.0
WLSH2_k127_4584314_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 326.0
WLSH2_k127_4584314_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000006671 247.0
WLSH2_k127_4584314_4 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000001652 118.0
WLSH2_k127_4584314_5 PAS domain K02488 - 2.7.7.65 0.000000000000000000000193 104.0
WLSH2_k127_4584314_6 PFAM response regulator receiver K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000006397 98.0
WLSH2_k127_4584314_7 - - - - 0.000000000000001254 89.0
WLSH2_k127_4672297_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 9.866e-262 833.0
WLSH2_k127_4672297_1 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 571.0
WLSH2_k127_4672297_10 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000001625 246.0
WLSH2_k127_4672297_11 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000001219 197.0
WLSH2_k127_4672297_12 - - - - 0.00000000000000000000000000000000000000000000000002138 189.0
WLSH2_k127_4672297_13 PFAM Peptidase - - - 0.0000000000000000000000000000000000001085 150.0
WLSH2_k127_4672297_14 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000000152 133.0
WLSH2_k127_4672297_15 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000005991 126.0
WLSH2_k127_4672297_16 Ribonuclease K03469 - 3.1.26.4 0.00000000000000000000000000308 116.0
WLSH2_k127_4672297_17 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000002419 113.0
WLSH2_k127_4672297_18 - - - - 0.000000000000000007876 93.0
WLSH2_k127_4672297_19 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000008499 93.0
WLSH2_k127_4672297_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 558.0
WLSH2_k127_4672297_20 Domain of unknown function (DUF749) - - - 0.00000001601 61.0
WLSH2_k127_4672297_21 - - - - 0.000006622 55.0
WLSH2_k127_4672297_22 V4R K07013 - - 0.0003642 52.0
WLSH2_k127_4672297_23 acetyltransferase - - - 0.0005698 51.0
WLSH2_k127_4672297_3 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 525.0
WLSH2_k127_4672297_4 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 362.0
WLSH2_k127_4672297_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 371.0
WLSH2_k127_4672297_6 PFAM Peptidase family M20 M25 M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 334.0
WLSH2_k127_4672297_7 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002857 288.0
WLSH2_k127_4672297_8 SMART ATPase, AAA type, core K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001885 271.0
WLSH2_k127_4672297_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001011 258.0
WLSH2_k127_4787641_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.41e-200 640.0
WLSH2_k127_4787641_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 472.0
WLSH2_k127_4787641_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 442.0
WLSH2_k127_4787641_3 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002627 271.0
WLSH2_k127_4787641_4 DEAD DEAH box helicase domain protein K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000007785 240.0
WLSH2_k127_4787641_5 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000002872 199.0
WLSH2_k127_4787641_6 Iron-sulphur cluster biosynthesis K15724 - - 0.00000000000000001388 87.0
WLSH2_k127_483821_0 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001996 291.0
WLSH2_k127_483821_1 - - - - 0.000000001036 69.0
WLSH2_k127_4867461_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 434.0
WLSH2_k127_4867461_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001658 278.0
WLSH2_k127_4867461_2 aminopeptidase activity K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003605 292.0
WLSH2_k127_4867461_3 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000104 203.0
WLSH2_k127_4867461_4 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.00000000000000000000000000000000000000000000000000001106 194.0
WLSH2_k127_4867461_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000001501 192.0
WLSH2_k127_4867461_6 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000002068 143.0
WLSH2_k127_4867461_7 Belongs to the UPF0248 family K09715 - - 0.00000000000000000001014 93.0
WLSH2_k127_4867461_8 membrane K08978 - - 0.00001315 51.0
WLSH2_k127_4990703_0 Type II/IV secretion system protein K07332 - - 2.556e-226 715.0
WLSH2_k127_4990703_1 Type II/IV secretion system protein K07332 - - 1.666e-219 703.0
WLSH2_k127_4990703_2 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002555 288.0
WLSH2_k127_4990703_3 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000001633 231.0
WLSH2_k127_4990703_4 Double zinc ribbon - - - 0.000000000000000000000000000000000000000000000001144 201.0
WLSH2_k127_4990703_5 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.0000000000000000000003987 100.0
WLSH2_k127_4990703_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000002641 51.0
WLSH2_k127_4990703_7 PFAM PKD domain containing protein - - - 0.00003872 54.0
WLSH2_k127_5074565_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001777 267.0
WLSH2_k127_5074565_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000001527 252.0
WLSH2_k127_5074565_2 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000004231 198.0
WLSH2_k127_5212065_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003217 280.0
WLSH2_k127_5212065_1 extracellular matrix structural constituent K02035 - - 0.000000000000002018 84.0
WLSH2_k127_5298070_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 570.0
WLSH2_k127_5298070_1 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001536 269.0
WLSH2_k127_5298070_2 amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000002803 181.0
WLSH2_k127_5298070_3 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000000000000000000001307 187.0
WLSH2_k127_5298070_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000001117 159.0
WLSH2_k127_5298070_6 - - - - 0.0000000000000000001984 91.0
WLSH2_k127_5298070_7 transcriptional regulators - - - 0.00000000000000156 81.0
WLSH2_k127_5332098_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 586.0
WLSH2_k127_5332098_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 532.0
WLSH2_k127_5332098_10 Flavodoxin domain - - - 0.0000000001068 69.0
WLSH2_k127_5332098_2 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001063 280.0
WLSH2_k127_5332098_3 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000007812 193.0
WLSH2_k127_5332098_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000001767 193.0
WLSH2_k127_5332098_5 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000001797 153.0
WLSH2_k127_5332098_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000001831 98.0
WLSH2_k127_5332098_7 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000007155 90.0
WLSH2_k127_5332098_8 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000000008188 86.0
WLSH2_k127_5332098_9 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000002416 74.0
WLSH2_k127_5411812_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 538.0
WLSH2_k127_5411812_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001295 284.0
WLSH2_k127_5411812_2 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002033 272.0
WLSH2_k127_5411812_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K08323 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000109 252.0
WLSH2_k127_5411812_4 Uridine phosphorylase - - - 0.0000000000000000000000000000000000009993 149.0
WLSH2_k127_5411812_5 archaeal coiled-coil protein - - - 0.0000002535 56.0
WLSH2_k127_5411812_6 helix_turn_helix ASNC type K03718 - - 0.00004848 55.0
WLSH2_k127_5457622_0 Tetratricopeptide repeat K07452 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 489.0
WLSH2_k127_5457622_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 413.0
WLSH2_k127_5457622_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 324.0
WLSH2_k127_5457622_3 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000167 268.0
WLSH2_k127_5457622_4 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001804 255.0
WLSH2_k127_5457622_5 - - - - 0.000000000000000000000000000000000000000000000000000007464 202.0
WLSH2_k127_5457622_6 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000003251 171.0
WLSH2_k127_5457622_7 Haloacid dehalogenase-like hydrolase K07025 - - 0.0001416 53.0
WLSH2_k127_5487288_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 353.0
WLSH2_k127_5487288_1 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 314.0
WLSH2_k127_5487288_10 PFAM beta-lactamase domain protein - - - 0.0000000000000000005022 89.0
WLSH2_k127_5487288_11 Belongs to the eIF-2B alpha beta delta subunits family - - - 0.000000004858 67.0
WLSH2_k127_5487288_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 288.0
WLSH2_k127_5487288_3 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000002433 247.0
WLSH2_k127_5487288_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000429 230.0
WLSH2_k127_5487288_5 archaeal Zn-finger protein - - - 0.000000000000000000000000000000000000000006191 161.0
WLSH2_k127_5487288_6 COG5598 Trimethylamine corrinoid methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000001137 165.0
WLSH2_k127_5487288_7 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000001314 153.0
WLSH2_k127_5487288_8 homolog of PrgY (pheromone shutdown protein) - - - 0.00000000000000000000000000000000005463 143.0
WLSH2_k127_5487288_9 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000172 94.0
WLSH2_k127_5571397_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000001624 258.0
WLSH2_k127_5571397_1 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000004722 218.0
WLSH2_k127_5571397_2 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000006085 102.0
WLSH2_k127_5637806_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 599.0
WLSH2_k127_5637806_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 460.0
WLSH2_k127_5637806_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 389.0
WLSH2_k127_5637806_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 330.0
WLSH2_k127_5637806_4 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000005334 247.0
WLSH2_k127_5637806_5 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000005906 162.0
WLSH2_k127_5637806_6 PAS domain K02488 - 2.7.7.65 0.0000000000003359 82.0
WLSH2_k127_5637806_7 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000001514 63.0
WLSH2_k127_5736248_0 COG0531 Amino acid transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 411.0
WLSH2_k127_5736248_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 314.0
WLSH2_k127_5736248_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001143 261.0
WLSH2_k127_5736248_3 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000000299 142.0
WLSH2_k127_5736248_4 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000003011 127.0
WLSH2_k127_5736248_5 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000005115 123.0
WLSH2_k127_5736248_6 Peptidase S8 K08651 - 3.4.21.66 0.00000000000000000000000149 122.0
WLSH2_k127_5736248_7 Peptidase family M28 - - - 0.00000000000000000000003035 110.0
WLSH2_k127_5736248_8 OmpA family - - - 0.000000000001324 83.0
WLSH2_k127_5820150_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.78e-316 982.0
WLSH2_k127_5820150_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 583.0
WLSH2_k127_5820150_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 414.0
WLSH2_k127_5820150_3 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 290.0
WLSH2_k127_5820150_4 Helix-turn-helix XRE-family like proteins K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000441 285.0
WLSH2_k127_5820150_5 - - - - 0.00000000000000000000153 103.0
WLSH2_k127_5820150_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000002558 96.0
WLSH2_k127_5820150_7 COG3277 RNA-binding protein involved in rRNA processing K07569 - - 0.00006465 48.0
WLSH2_k127_5829421_0 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 504.0
WLSH2_k127_5829421_1 PFAM response regulator receiver K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 357.0
WLSH2_k127_5829421_2 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000000003464 195.0
WLSH2_k127_5829421_3 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000000000000000000000000000000000000000000001095 191.0
WLSH2_k127_5829421_4 MFS/sugar transport protein - - - 0.000000000000000000000000000000000002074 154.0
WLSH2_k127_5829421_5 Pfam:KaiC - - - 0.00000000000000000000000000000001745 139.0
WLSH2_k127_5829421_6 KaiC - - - 0.000000000000000000000000006299 121.0
WLSH2_k127_5829421_7 helix_turn_helix ASNC type K06154 - - 0.0000000000000000000000002577 109.0
WLSH2_k127_5829421_8 Protein of unknown function (DUF835) - - - 0.000000000001147 82.0
WLSH2_k127_5829421_9 EamA-like transporter family - - - 0.000002568 59.0
WLSH2_k127_5871674_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003341 269.0
WLSH2_k127_5871674_1 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001281 243.0
WLSH2_k127_5871674_2 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000005 232.0
WLSH2_k127_5871674_3 solute binding protein K02035 - - 0.000001528 61.0
WLSH2_k127_5871674_4 - - - - 0.000005306 55.0
WLSH2_k127_5871674_5 PFAM integrase family protein - - - 0.0001484 47.0
WLSH2_k127_59255_0 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 512.0
WLSH2_k127_59255_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 445.0
WLSH2_k127_59255_10 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000008285 130.0
WLSH2_k127_59255_11 - - - - 0.000000000000000000000000000003405 132.0
WLSH2_k127_59255_12 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000613 97.0
WLSH2_k127_59255_13 Domain of unknown function (DUF296) K06934 - - 0.0000000000000004548 83.0
WLSH2_k127_59255_14 bacterial-type flagellum-dependent cell motility - - - 0.000000000000003967 90.0
WLSH2_k127_59255_15 - - - - 0.000000000000287 73.0
WLSH2_k127_59255_16 Major Facilitator Superfamily - - - 0.000000000002159 79.0
WLSH2_k127_59255_17 Protein of unknown function (DUF998) - - - 0.00000000206 66.0
WLSH2_k127_59255_18 Protein of unknown function DUF131 - - - 0.0000001511 60.0
WLSH2_k127_59255_19 GDSL-like Lipase/Acylhydrolase family - - - 0.0000005617 63.0
WLSH2_k127_59255_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007497 286.0
WLSH2_k127_59255_3 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003809 261.0
WLSH2_k127_59255_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000009482 252.0
WLSH2_k127_59255_5 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000000551 242.0
WLSH2_k127_59255_6 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000001602 215.0
WLSH2_k127_59255_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000002003 181.0
WLSH2_k127_59255_8 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.000000000000000000000000000000000000006047 165.0
WLSH2_k127_59255_9 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000008783 130.0
WLSH2_k127_6020_0 transcription regulator activity - - - 0.00000000000000000000000000000000004223 140.0
WLSH2_k127_6020_1 Protein of unknown function (DUF835) - - - 0.00002439 57.0
WLSH2_k127_6058320_0 ABC transporter K00400,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 364.0
WLSH2_k127_6058320_1 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000007138 237.0
WLSH2_k127_6058320_2 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000004626 144.0
WLSH2_k127_6058320_3 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000002251 149.0
WLSH2_k127_6058320_4 PFAM ABC-type thiamin-related transport system, permease component 1 K16925 - - 0.00000000000000000000000000002463 128.0
WLSH2_k127_6058320_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function - - - 0.00000000000002803 81.0
WLSH2_k127_6058320_6 - - - - 0.0000000008817 66.0
WLSH2_k127_6058320_7 helix_turn_helix, Arsenical Resistance Operon Repressor K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00001507 58.0
WLSH2_k127_6292493_0 GXGXG motif - - - 3.188e-285 906.0
WLSH2_k127_6292493_1 Glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 615.0
WLSH2_k127_6292493_10 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 412.0
WLSH2_k127_6292493_11 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 386.0
WLSH2_k127_6292493_12 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 354.0
WLSH2_k127_6292493_13 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 333.0
WLSH2_k127_6292493_14 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 328.0
WLSH2_k127_6292493_15 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 307.0
WLSH2_k127_6292493_16 Bacterial Na+/H+ antiporter B (NhaB) K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005149 283.0
WLSH2_k127_6292493_17 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005093 229.0
WLSH2_k127_6292493_18 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000001093 231.0
WLSH2_k127_6292493_19 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000001969 211.0
WLSH2_k127_6292493_2 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 597.0
WLSH2_k127_6292493_20 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000001038 186.0
WLSH2_k127_6292493_21 OsmC-like protein - - - 0.00000000000000000000000000000000058 136.0
WLSH2_k127_6292493_22 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000008822 132.0
WLSH2_k127_6292493_23 Major Facilitator - - - 0.00000000000000000000000000009115 130.0
WLSH2_k127_6292493_24 - - - - 0.000000000000000000000000000281 121.0
WLSH2_k127_6292493_25 - - - - 0.000000000000004677 78.0
WLSH2_k127_6292493_26 SpoVT / AbrB like domain - - - 0.0000000000106 68.0
WLSH2_k127_6292493_3 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 554.0
WLSH2_k127_6292493_4 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 528.0
WLSH2_k127_6292493_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 519.0
WLSH2_k127_6292493_6 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 455.0
WLSH2_k127_6292493_7 histidyl-tRNA aminoacylation K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 452.0
WLSH2_k127_6292493_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 436.0
WLSH2_k127_6292493_9 TIGRFAM Small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 414.0
WLSH2_k127_6422280_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 436.0
WLSH2_k127_6422280_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 302.0
WLSH2_k127_6422280_2 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 289.0
WLSH2_k127_6422280_3 Oxidoreductase domain protein K18855 - 1.1.1.374 0.000000000000000000000000000000000000000000000000000000000000000000000000000006393 273.0
WLSH2_k127_6422280_4 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000000000000000000000001051 147.0
WLSH2_k127_6422280_5 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.000000000000000000001589 97.0
WLSH2_k127_6422280_6 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000003119 100.0
WLSH2_k127_6422280_7 Trm112p-like protein - - - 0.0000000000005985 74.0
WLSH2_k127_6439336_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1485.0
WLSH2_k127_6439336_1 MCM OB domain K10726 - - 2.582e-216 692.0
WLSH2_k127_6439336_10 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 323.0
WLSH2_k127_6439336_11 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004662 284.0
WLSH2_k127_6439336_12 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007474 256.0
WLSH2_k127_6439336_13 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001078 247.0
WLSH2_k127_6439336_14 ATPases associated with a variety of cellular activities K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000001953 233.0
WLSH2_k127_6439336_15 PFAM Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000004009 228.0
WLSH2_k127_6439336_16 Radical SAM domain protein K09711 - - 0.0000000000000000000000000000000000000000000000000000000001246 215.0
WLSH2_k127_6439336_17 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000009739 218.0
WLSH2_k127_6439336_18 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000006233 185.0
WLSH2_k127_6439336_19 NMD3 family K07562 - - 0.0000000000000000000000000000000000000000000000223 183.0
WLSH2_k127_6439336_2 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 513.0
WLSH2_k127_6439336_20 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000002152 174.0
WLSH2_k127_6439336_21 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000001411 163.0
WLSH2_k127_6439336_22 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000007779 152.0
WLSH2_k127_6439336_23 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000001208 115.0
WLSH2_k127_6439336_24 Protein of unknown function (DUF424) K09148 - - 0.0000000000000000000009234 99.0
WLSH2_k127_6439336_25 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000003023 83.0
WLSH2_k127_6439336_26 Listeria-Bacteroides repeat domain (List_Bact_rpt) - - - 0.00000000000001112 88.0
WLSH2_k127_6439336_27 Pfam:DUF1628 - - - 0.00000000001307 72.0
WLSH2_k127_6439336_28 PFAM PKD domain containing protein - - - 0.0000000002283 73.0
WLSH2_k127_6439336_29 RDD family - - - 0.0000000806 60.0
WLSH2_k127_6439336_3 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 475.0
WLSH2_k127_6439336_30 Double zinc ribbon - - - 0.00001076 58.0
WLSH2_k127_6439336_31 - - - - 0.0003691 51.0
WLSH2_k127_6439336_32 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.000455 49.0
WLSH2_k127_6439336_4 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 389.0
WLSH2_k127_6439336_5 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 389.0
WLSH2_k127_6439336_6 FAD binding domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 357.0
WLSH2_k127_6439336_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 340.0
WLSH2_k127_6439336_8 Rad51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 327.0
WLSH2_k127_6439336_9 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 324.0
WLSH2_k127_6517310_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 484.0
WLSH2_k127_6517310_1 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 366.0
WLSH2_k127_6517310_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 357.0
WLSH2_k127_6517310_3 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 312.0
WLSH2_k127_6517310_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000005859 220.0
WLSH2_k127_6517310_5 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000002093 220.0
WLSH2_k127_6517310_6 Efflux ABC transporter, permease protein K02004 - - 0.00000000000000000000000000000000927 147.0
WLSH2_k127_6517310_7 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000000002958 108.0
WLSH2_k127_6517310_8 - - - - 0.0000000000000000000009246 105.0
WLSH2_k127_6535147_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 599.0
WLSH2_k127_6535147_1 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 546.0
WLSH2_k127_6535147_10 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000002979 142.0
WLSH2_k127_6535147_11 Acetolactate synthase small K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000004442 111.0
WLSH2_k127_6535147_12 PFAM CBS domain containing protein - - - 0.000000000000000000000002018 108.0
WLSH2_k127_6535147_13 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.00005936 47.0
WLSH2_k127_6535147_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 430.0
WLSH2_k127_6535147_3 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 311.0
WLSH2_k127_6535147_4 Isocitrate isopropylmalate dehydrogenase K05824 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0047046,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 291.0
WLSH2_k127_6535147_5 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001853 287.0
WLSH2_k127_6535147_6 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000004812 259.0
WLSH2_k127_6535147_7 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000001552 237.0
WLSH2_k127_6535147_8 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000002503 194.0
WLSH2_k127_6535147_9 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.000000000000000000000000000000000001706 147.0
WLSH2_k127_654683_0 Aminotransferase class-III K00823,K03918,K20428 - 2.6.1.19,2.6.1.33,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 424.0
WLSH2_k127_654683_1 PFAM elongation factor Tu domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 371.0
WLSH2_k127_654683_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 299.0
WLSH2_k127_654683_3 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000003957 195.0
WLSH2_k127_654683_4 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.000000000000000000000000000000000000000004478 157.0
WLSH2_k127_654683_5 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000001747 170.0
WLSH2_k127_654683_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000002646 80.0
WLSH2_k127_654683_7 - - - - 0.00000001266 61.0
WLSH2_k127_654683_8 Acetyltransferase (GNAT) family - - - 0.0003196 46.0
WLSH2_k127_6568973_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.252e-253 793.0
WLSH2_k127_6568973_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.966e-243 757.0
WLSH2_k127_6568973_10 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.0000000000000000000000000000000000000005593 164.0
WLSH2_k127_6568973_11 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000002978 153.0
WLSH2_k127_6568973_12 CAAX protease self-immunity - - - 0.00000000000000000000000000000005879 141.0
WLSH2_k127_6568973_13 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.0000000000000000000000000000002426 130.0
WLSH2_k127_6568973_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000007696 106.0
WLSH2_k127_6568973_15 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000000000000000000004776 100.0
WLSH2_k127_6568973_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000006281 102.0
WLSH2_k127_6568973_17 cheY-homologous receiver domain - - - 0.0000000000000000005785 95.0
WLSH2_k127_6568973_18 RNA binding K09736 - - 0.00000000000000001013 87.0
WLSH2_k127_6568973_19 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.0000000004971 62.0
WLSH2_k127_6568973_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 446.0
WLSH2_k127_6568973_20 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000001347 72.0
WLSH2_k127_6568973_3 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 371.0
WLSH2_k127_6568973_4 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 333.0
WLSH2_k127_6568973_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000671 275.0
WLSH2_k127_6568973_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002934 255.0
WLSH2_k127_6568973_7 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000005966 168.0
WLSH2_k127_6568973_8 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000001764 162.0
WLSH2_k127_6568973_9 GvpD gas vesicle protein - - - 0.0000000000000000000000000000000000000003096 157.0
WLSH2_k127_6626860_0 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000001301 207.0
WLSH2_k127_6626860_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000001655 136.0
WLSH2_k127_6626860_2 Methyltransferase type 11 - - - 0.0000000000000002508 82.0
WLSH2_k127_6626860_3 EamA-like transporter family - - - 0.0001316 52.0
WLSH2_k127_6749026_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 337.0
WLSH2_k127_6749026_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 311.0
WLSH2_k127_6749026_10 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000005529 86.0
WLSH2_k127_6749026_2 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005122 230.0
WLSH2_k127_6749026_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000004065 213.0
WLSH2_k127_6749026_4 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000005499 215.0
WLSH2_k127_6749026_5 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000007389 207.0
WLSH2_k127_6749026_6 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000003418 197.0
WLSH2_k127_6749026_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000006368 196.0
WLSH2_k127_6749026_8 hmm pf03415 K08587 - 3.4.22.8 0.0000000000000000000005209 110.0
WLSH2_k127_6749026_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000001344 94.0
WLSH2_k127_6752837_0 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000001506 233.0
WLSH2_k127_6752837_1 PFAM MscS Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000001448 157.0
WLSH2_k127_6752837_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.00000000000000001842 99.0
WLSH2_k127_6752837_3 PKD domain containing protein - - - 0.00000000000002344 89.0
WLSH2_k127_6752837_4 ABC-type multidrug transport system, permease component K01992 - - 0.0000000002273 69.0
WLSH2_k127_6752837_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000478 66.0
WLSH2_k127_6827309_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1046.0
WLSH2_k127_6827309_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.000000000000000000000000000000000000000000000000000000003369 209.0
WLSH2_k127_6827309_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000004289 170.0
WLSH2_k127_7024773_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 308.0
WLSH2_k127_7024773_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002667 287.0
WLSH2_k127_7024773_3 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.0008753 49.0
WLSH2_k127_70356_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1069.0
WLSH2_k127_70356_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000008727 99.0
WLSH2_k127_7051043_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1031.0
WLSH2_k127_7051043_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 593.0
WLSH2_k127_7051043_10 - - - - 0.000000001412 61.0
WLSH2_k127_7051043_2 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003297 248.0
WLSH2_k127_7051043_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000002434 247.0
WLSH2_k127_7051043_4 nitroreductase - - - 0.0000000000000000000000000000000000000000000000001446 181.0
WLSH2_k127_7051043_5 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000009671 168.0
WLSH2_k127_7051043_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.0000000000000000000000000000000000002702 144.0
WLSH2_k127_7051043_7 DMT(Drug metabolite transporter) superfamily permease - - - 0.0000000000000000000000000005285 125.0
WLSH2_k127_7051043_8 Protein of unknown function (DUF1616) - - - 0.00000000000000000000003345 107.0
WLSH2_k127_7051043_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000004548 82.0
WLSH2_k127_7056328_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 461.0
WLSH2_k127_7056328_1 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 354.0
WLSH2_k127_7056328_10 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.000000000000000000000000000000000000001271 170.0
WLSH2_k127_7056328_11 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.0000000000000000000000000000000001556 154.0
WLSH2_k127_7056328_12 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000004298 142.0
WLSH2_k127_7056328_13 Tetratricopeptide repeat - - - 0.00000000000000004913 95.0
WLSH2_k127_7056328_14 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.000000000000007198 83.0
WLSH2_k127_7056328_15 serine-type endopeptidase activity - - - 0.0000000005198 74.0
WLSH2_k127_7056328_16 diguanylate cyclase - - - 0.00000002363 67.0
WLSH2_k127_7056328_17 Lamin Tail Domain - - - 0.0000009373 63.0
WLSH2_k127_7056328_18 efflux transmembrane transporter activity K02004 - - 0.00002113 58.0
WLSH2_k127_7056328_19 ABC transporter K02003,K02004 - - 0.00005524 55.0
WLSH2_k127_7056328_2 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 316.0
WLSH2_k127_7056328_20 MacB-like periplasmic core domain K02004 - - 0.00006382 56.0
WLSH2_k127_7056328_21 Protein of unknown function (DUF1616) - - - 0.0001337 53.0
WLSH2_k127_7056328_22 LexA-binding, inner membrane-associated putative hydrolase - - - 0.0002935 50.0
WLSH2_k127_7056328_3 PFAM Iron-containing alcohol dehydrogenase K00005,K08317 - 1.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000002331 248.0
WLSH2_k127_7056328_4 Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000000000000000000000000000000248 201.0
WLSH2_k127_7056328_5 TIGRFAM PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000002073 205.0
WLSH2_k127_7056328_6 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000004068 199.0
WLSH2_k127_7056328_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000005328 192.0
WLSH2_k127_7056328_8 Desulfoferrodoxin K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000001285 179.0
WLSH2_k127_7056328_9 Acts probably as a methyl group carrier between MttB and either MtbA or MtaA K14084 - - 0.000000000000000000000000000000000000000002097 166.0
WLSH2_k127_7056917_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 486.0
WLSH2_k127_7056917_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 411.0
WLSH2_k127_7056917_2 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000007659 203.0
WLSH2_k127_7056917_3 - - - - 0.0000000000003288 76.0
WLSH2_k127_7146983_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 6.309e-209 670.0
WLSH2_k127_7146983_1 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 571.0
WLSH2_k127_7146983_2 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000006434 214.0
WLSH2_k127_7146983_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function - - - 0.000000000000000000009441 101.0
WLSH2_k127_7146983_4 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000051 96.0
WLSH2_k127_7146983_5 Glycosyl transferase family 2 - - - 0.00000000000000008408 89.0
WLSH2_k127_7146983_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000003986 82.0
WLSH2_k127_7146983_7 Rubrerythrin - - - 0.000009837 56.0
WLSH2_k127_7146983_8 DNA polymerase beta domain-containing protein region - - - 0.00005027 53.0
WLSH2_k127_7149474_0 ATP-grasp domain K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 351.0
WLSH2_k127_7149474_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 341.0
WLSH2_k127_7149474_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000001056 243.0
WLSH2_k127_7149474_3 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000000000000001233 202.0
WLSH2_k127_7149474_4 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000001376 204.0
WLSH2_k127_7149474_5 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.0000000000000000000000000000000000003238 154.0
WLSH2_k127_7149474_6 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000004715 148.0
WLSH2_k127_7149474_7 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.00000000000000000000003355 111.0
WLSH2_k127_7149474_8 GTPase activity K00514,K07874,K07875 GO:0000003,GO:0000045,GO:0000139,GO:0000166,GO:0000278,GO:0000280,GO:0000281,GO:0000407,GO:0000902,GO:0000904,GO:0000910,GO:0001816,GO:0001882,GO:0001883,GO:0002790,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005783,GO:0005789,GO:0005793,GO:0005794,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0006886,GO:0006888,GO:0006890,GO:0006897,GO:0006900,GO:0006901,GO:0006903,GO:0006914,GO:0006928,GO:0006950,GO:0006952,GO:0006996,GO:0007017,GO:0007018,GO:0007030,GO:0007033,GO:0007049,GO:0007112,GO:0007140,GO:0007154,GO:0007155,GO:0007165,GO:0007264,GO:0007265,GO:0007267,GO:0007275,GO:0007276,GO:0007399,GO:0008088,GO:0008089,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009306,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009893,GO:0009894,GO:0009914,GO:0009987,GO:0010256,GO:0010506,GO:0010604,GO:0010646,GO:0010647,GO:0010720,GO:0010769,GO:0010770,GO:0010817,GO:0010970,GO:0010975,GO:0010976,GO:0012505,GO:0012506,GO:0015031,GO:0015833,GO:0016020,GO:0016032,GO:0016043,GO:0016050,GO:0016192,GO:0016236,GO:0016241,GO:0016462,GO:0016477,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019058,GO:0019068,GO:0019222,GO:0019538,GO:0019953,GO:0022008,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0023061,GO:0030072,GO:0030133,GO:0030154,GO:0030252,GO:0030334,GO:0030658,GO:0030659,GO:0030705,GO:0031090,GO:0031323,GO:0031325,GO:0031329,GO:0031344,GO:0031346,GO:0031396,GO:0031398,GO:0031399,GO:0031401,GO:0031410,GO:0031589,GO:0031982,GO:0031984,GO:0032024,GO:0032153,GO:0032154,GO:0032155,GO:0032268,GO:0032270,GO:0032400,GO:0032401,GO:0032402,GO:0032482,GO:0032501,GO:0032502,GO:0032504,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032637,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0033036,GO:0033043,GO:0033059,GO:0033116,GO:0033206,GO:0033365,GO:0033500,GO:0034045,GO:0034067,GO:0034446,GO:0034613,GO:0034622,GO:0035459,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0040011,GO:0040012,GO:0042175,GO:0042470,GO:0042592,GO:0042742,GO:0042886,GO:0043025,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043473,GO:0043687,GO:0043933,GO:0044085,GO:0044087,GO:0044088,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044297,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044464,GO:0044703,GO:0045184,GO:0045202,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0046879,GO:0046883,GO:0046887,GO:0046903,GO:0046907,GO:0047496,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0048232,GO:0048285,GO:0048468,GO:0048518,GO:0048522,GO:0048609,GO:0048699,GO:0048731,GO:0048770,GO:0048814,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0050663,GO:0050708,GO:0050714,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050796,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051270,GO:0051301,GO:0051321,GO:0051338,GO:0051347,GO:0051438,GO:0051443,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0051668,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051875,GO:0051904,GO:0051905,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0061024,GO:0061640,GO:0061919,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070382,GO:0070727,GO:0070925,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0072384,GO:0072606,GO:0072657,GO:0072741,GO:0080090,GO:0090087,GO:0090110,GO:0090114,GO:0090276,GO:0090277,GO:0097159,GO:0097367,GO:0097458,GO:0097708,GO:0098542,GO:0098588,GO:0098590,GO:0098657,GO:0098791,GO:0098793,GO:0098805,GO:0098827,GO:0098930,GO:0099111,GO:0099503,GO:0099518,GO:0120035,GO:0140013,GO:1900006,GO:1901265,GO:1901363,GO:1901564,GO:1902115,GO:1903018,GO:1903020,GO:1903046,GO:1903047,GO:1903320,GO:1903322,GO:1903530,GO:1903532,GO:1904666,GO:1904668,GO:1904951,GO:1905037,GO:1905345,GO:1990778,GO:2000026,GO:2000145,GO:2000785 1.3.5.6 0.0000000000000000000004522 106.0
WLSH2_k127_7149474_9 OmpA family - - - 0.000000000003836 74.0
WLSH2_k127_7265125_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000001862 267.0
WLSH2_k127_7265125_1 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008556 248.0
WLSH2_k127_7265125_2 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000004075 203.0
WLSH2_k127_7265125_3 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000008689 185.0
WLSH2_k127_7512196_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 4.243e-212 674.0
WLSH2_k127_7512196_1 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 542.0
WLSH2_k127_7512196_10 Psort location CytoplasmicMembrane, score - - - 0.00000000000000001061 96.0
WLSH2_k127_7512196_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 286.0
WLSH2_k127_7512196_3 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003493 292.0
WLSH2_k127_7512196_4 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002885 274.0
WLSH2_k127_7512196_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000001963 201.0
WLSH2_k127_7512196_6 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000003859 173.0
WLSH2_k127_7512196_7 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.00000000000000000000000000002266 117.0
WLSH2_k127_7512196_8 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000003639 95.0
WLSH2_k127_7512196_9 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000008376 83.0
WLSH2_k127_7514532_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.49e-273 861.0
WLSH2_k127_7514532_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 2.791e-211 671.0
WLSH2_k127_7514532_10 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000006244 150.0
WLSH2_k127_7514532_11 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.0000000000000000000000000000001423 124.0
WLSH2_k127_7514532_12 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000001388 127.0
WLSH2_k127_7514532_13 Fcf1 K07158 - - 0.00000000000000000000002326 103.0
WLSH2_k127_7514532_14 4Fe-4S ferredoxin iron-sulfur binding domain protein K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000004329 98.0
WLSH2_k127_7514532_15 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000006651 96.0
WLSH2_k127_7514532_16 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000003021 89.0
WLSH2_k127_7514532_17 guanyl-nucleotide exchange factor activity K14475,K20276 - - 0.0009002 51.0
WLSH2_k127_7514532_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 560.0
WLSH2_k127_7514532_3 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 548.0
WLSH2_k127_7514532_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 396.0
WLSH2_k127_7514532_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 347.0
WLSH2_k127_7514532_6 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004856 272.0
WLSH2_k127_7514532_7 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000002092 223.0
WLSH2_k127_7514532_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000002393 207.0
WLSH2_k127_7514532_9 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000002994 161.0
WLSH2_k127_7622968_0 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001094 286.0
WLSH2_k127_7622968_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000007251 234.0
WLSH2_k127_7622968_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000009519 213.0
WLSH2_k127_7622968_3 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000002219 91.0
WLSH2_k127_7623279_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 412.0
WLSH2_k127_7623279_1 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 366.0
WLSH2_k127_7623279_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 304.0
WLSH2_k127_7623279_3 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002573 284.0
WLSH2_k127_7623279_4 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001329 242.0
WLSH2_k127_7623279_5 Cache domain - - - 0.000000000000000000000000000000000000000000001202 188.0
WLSH2_k127_7623279_6 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000003716 174.0
WLSH2_k127_7623279_7 Chemotaxis protein cheW K03408 - - 0.0000000000000000000000000000000006907 135.0
WLSH2_k127_7623279_8 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000004636 131.0
WLSH2_k127_7742106_0 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 365.0
WLSH2_k127_7742106_1 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000259 164.0
WLSH2_k127_7742106_2 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000000000000415 70.0
WLSH2_k127_7742106_3 Major Facilitator Superfamily K08222 - - 0.000000000009852 77.0
WLSH2_k127_7742106_4 denitrification pathway - - - 0.000000004551 68.0
WLSH2_k127_7804636_0 helicase superfamily c-terminal domain K03724 - - 4.193e-302 953.0
WLSH2_k127_7804636_1 Type II/IV secretion system protein K07332 - - 2.724e-224 709.0
WLSH2_k127_7804636_10 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000003605 240.0
WLSH2_k127_7804636_11 Protein of unknown function (DUF531) K09725 - - 0.0000000000000000000000000000000000000000000000000000033 196.0
WLSH2_k127_7804636_12 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000003098 208.0
WLSH2_k127_7804636_13 Double zinc ribbon - - - 0.000000000000000000000000000000000000000000008212 188.0
WLSH2_k127_7804636_14 - - - - 0.000000000000000000000000374 110.0
WLSH2_k127_7804636_15 Nitroreductase family K19285,K19286 - 1.5.1.38,1.5.1.39 0.00000000000000000000004554 109.0
WLSH2_k127_7804636_16 toxin activity - - - 0.00000000000000000000006325 110.0
WLSH2_k127_7804636_17 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000002173 82.0
WLSH2_k127_7804636_18 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000005464 60.0
WLSH2_k127_7804636_2 Type II/IV secretion system protein K07332 - - 4.927e-224 709.0
WLSH2_k127_7804636_3 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 616.0
WLSH2_k127_7804636_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 534.0
WLSH2_k127_7804636_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 472.0
WLSH2_k127_7804636_6 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 407.0
WLSH2_k127_7804636_7 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 399.0
WLSH2_k127_7804636_8 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 313.0
WLSH2_k127_7804636_9 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000176 280.0
WLSH2_k127_7905698_0 Proton-conducting membrane transporter K22168 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 392.0
WLSH2_k127_7905698_1 Proton-conducting membrane transporter K00343,K22169 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 381.0
WLSH2_k127_7905698_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000001377 219.0
WLSH2_k127_7905698_11 UbiA prenyltransferase family K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000001529 224.0
WLSH2_k127_7905698_12 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000002081 212.0
WLSH2_k127_7905698_13 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000000000000000002161 196.0
WLSH2_k127_7905698_14 methyltransferase small K07579 - - 0.0000000000000000000000000000000000000000000002571 174.0
WLSH2_k127_7905698_15 PHP-associated - - - 0.0000000000000000000000000000000001373 140.0
WLSH2_k127_7905698_16 PIN domain of ribonuclease K07060 GO:0000469,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0030490,GO:0030684,GO:0030688,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1990904 - 0.00000000000000000000000002125 114.0
WLSH2_k127_7905698_17 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000001716 111.0
WLSH2_k127_7905698_18 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000007266 89.0
WLSH2_k127_7905698_19 Acetyltransferase (GNAT) domain - - - 0.0000000000000009198 85.0
WLSH2_k127_7905698_2 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 350.0
WLSH2_k127_7905698_20 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000001239 57.0
WLSH2_k127_7905698_3 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 346.0
WLSH2_k127_7905698_4 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 307.0
WLSH2_k127_7905698_5 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 302.0
WLSH2_k127_7905698_6 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005005 271.0
WLSH2_k127_7905698_7 ABC-type dipeptide oligopeptide nickel transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003658 269.0
WLSH2_k127_7905698_8 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000156 238.0
WLSH2_k127_7905698_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000249 239.0
WLSH2_k127_7927597_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K02192,K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363 1.6.3.4,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 312.0
WLSH2_k127_7927597_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000002319 113.0
WLSH2_k127_8013053_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 477.0
WLSH2_k127_8013053_1 - - - - 0.000000000000000000000000000000000000000000000000004759 189.0
WLSH2_k127_8013053_2 Acetyltransferase (GNAT) domain - - - 0.0003156 53.0
WLSH2_k127_8321605_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 479.0
WLSH2_k127_8321605_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 422.0
WLSH2_k127_8321605_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 373.0
WLSH2_k127_8345837_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000001759 106.0
WLSH2_k127_8351806_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001256 264.0
WLSH2_k127_8351806_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000005085 237.0
WLSH2_k127_8351806_2 structural constituent of ribosome K02984 - - 0.000000000000000000000000000000000000000000000000000000000000002948 227.0
WLSH2_k127_8351806_3 PKD domain - - - 0.000000003666 70.0
WLSH2_k127_8351806_4 peptidase M36 K01417 - - 0.00006075 56.0
WLSH2_k127_8384027_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000001482 217.0
WLSH2_k127_8384027_1 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.00000000000000000000000000000000000000000000000000004225 194.0
WLSH2_k127_8384027_2 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000004066 162.0
WLSH2_k127_8384027_3 Belongs to the PDCD5 family K06875 - - 0.000000000000000000001061 98.0
WLSH2_k127_8384027_4 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000004171 93.0
WLSH2_k127_8384027_5 Domain of unknown function (DUF373) K08975 - - 0.0000000000000002711 79.0
WLSH2_k127_8384027_6 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000002129 70.0
WLSH2_k127_8384027_7 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.00000008285 55.0
WLSH2_k127_8403128_0 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000851 298.0
WLSH2_k127_8403128_1 tripeptidyl-peptidase activity - - - 0.000000000000000001037 102.0
WLSH2_k127_8403128_2 Belongs to the peptidase S8 family - - - 0.0000000000009554 78.0
WLSH2_k127_8403128_3 amine dehydrogenase activity - - - 0.0000001924 65.0
WLSH2_k127_8403128_4 membrane-associated protein domain - - - 0.0001472 51.0
WLSH2_k127_8418220_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.813e-261 840.0
WLSH2_k127_8418220_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 2.666e-253 796.0
WLSH2_k127_8418220_10 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001195 253.0
WLSH2_k127_8418220_11 PFAM Circadian clock protein KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001445 248.0
WLSH2_k127_8418220_12 Peptidase M14, carboxypeptidase A K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000000000000000000000000007669 250.0
WLSH2_k127_8418220_13 Nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000004174 199.0
WLSH2_k127_8418220_14 Nicotinamide-nucleotide adenylyltransferase K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.0000000000000000000000000000000000000000000006538 172.0
WLSH2_k127_8418220_15 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001765 168.0
WLSH2_k127_8418220_16 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000009378 161.0
WLSH2_k127_8418220_17 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000001399 175.0
WLSH2_k127_8418220_18 Uncharacterised protein family (UPF0179) K09730 - - 0.0000000000000000000000000000000963 128.0
WLSH2_k127_8418220_19 Pfam:DUF552 K09152 - - 0.00000000000000000000000000004946 120.0
WLSH2_k127_8418220_2 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 9.489e-202 638.0
WLSH2_k127_8418220_20 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000005626 122.0
WLSH2_k127_8418220_21 Response regulator receiver domain - - - 0.0000000000000000000000000133 113.0
WLSH2_k127_8418220_22 Peptidase family C25 K03546,K20074 - 3.1.3.16 0.0000000000000000000000002402 125.0
WLSH2_k127_8418220_23 PFAM TPR repeat-containing protein - - - 0.0000000000000000000001536 112.0
WLSH2_k127_8418220_24 DNA-binding transcription factor activity K18297 - - 0.0000000000000000000001949 107.0
WLSH2_k127_8418220_25 PFAM Formiminotransferase-cyclodeaminase - - - 0.000000000000000000487 96.0
WLSH2_k127_8418220_26 MoaE protein K21142 - 2.8.1.12 0.00000000000000001251 85.0
WLSH2_k127_8418220_27 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.00000000000004756 81.0
WLSH2_k127_8418220_28 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000007395 78.0
WLSH2_k127_8418220_29 KEOPS complex Cgi121-like subunit K09119 - - 0.000000000005082 74.0
WLSH2_k127_8418220_3 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 618.0
WLSH2_k127_8418220_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 584.0
WLSH2_k127_8418220_5 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 452.0
WLSH2_k127_8418220_6 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 415.0
WLSH2_k127_8418220_7 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 371.0
WLSH2_k127_8418220_8 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 346.0
WLSH2_k127_8418220_9 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 351.0
WLSH2_k127_8546474_0 aldo keto reductase family K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 462.0
WLSH2_k127_8546474_1 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 369.0
WLSH2_k127_8546474_2 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000000000121 239.0
WLSH2_k127_8546474_3 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000004994 199.0
WLSH2_k127_8546474_4 helix_turn_helix ASNC type - - - 0.00000002186 65.0
WLSH2_k127_8546474_5 - - - - 0.00005148 55.0
WLSH2_k127_86370_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 450.0
WLSH2_k127_86370_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 333.0
WLSH2_k127_86370_10 - - - - 0.0000000000000000000000008213 110.0
WLSH2_k127_86370_11 COG0500 SAM-dependent methyltransferases - - - 0.00000000000002583 83.0
WLSH2_k127_86370_12 COG0784 FOG CheY-like receiver - - - 0.00000000000003152 87.0
WLSH2_k127_86370_13 - - - - 0.0000000000004569 73.0
WLSH2_k127_86370_14 PFAM Radical SAM domain protein K22227 - - 0.0000001027 61.0
WLSH2_k127_86370_15 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0001095 50.0
WLSH2_k127_86370_2 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
WLSH2_k127_86370_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000126 261.0
WLSH2_k127_86370_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000002012 240.0
WLSH2_k127_86370_5 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000001482 205.0
WLSH2_k127_86370_6 Ribosomal S13/S15 N-terminal domain K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001031 181.0
WLSH2_k127_86370_7 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000001204 128.0
WLSH2_k127_86370_8 Prokaryotic homologs of the JAB domain - - - 0.00000000000000000000000000009068 132.0
WLSH2_k127_86370_9 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000002347 112.0
WLSH2_k127_8700529_0 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 395.0
WLSH2_k127_8700529_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 381.0
WLSH2_k127_8700529_3 Fibronectin type III domain protein K12567 - 2.7.11.1 0.00009835 54.0
WLSH2_k127_872772_0 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 379.0
WLSH2_k127_872772_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000001719 108.0
WLSH2_k127_872772_2 Fe-S cluster domain protein K03753 - - 0.0000000000000001583 86.0
WLSH2_k127_8828775_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1110.0
WLSH2_k127_8828775_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1080.0
WLSH2_k127_8828775_10 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 355.0
WLSH2_k127_8828775_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 319.0
WLSH2_k127_8828775_12 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004662 282.0
WLSH2_k127_8828775_13 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001866 263.0
WLSH2_k127_8828775_14 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000002246 229.0
WLSH2_k127_8828775_15 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000003618 222.0
WLSH2_k127_8828775_16 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000009305 195.0
WLSH2_k127_8828775_17 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000001758 180.0
WLSH2_k127_8828775_18 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000003818 175.0
WLSH2_k127_8828775_19 - - - - 0.0000000000000000000000000000000000186 145.0
WLSH2_k127_8828775_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.193e-271 851.0
WLSH2_k127_8828775_20 cell redox homeostasis - - - 0.00000000000000000000000000004237 121.0
WLSH2_k127_8828775_21 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000009399 121.0
WLSH2_k127_8828775_22 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000005226 113.0
WLSH2_k127_8828775_23 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000002534 113.0
WLSH2_k127_8828775_24 response regulator, receiver - - - 0.00000000000000000009241 106.0
WLSH2_k127_8828775_25 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000211 92.0
WLSH2_k127_8828775_26 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000003969 86.0
WLSH2_k127_8828775_27 - - - - 0.0000000000004188 79.0
WLSH2_k127_8828775_28 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000003366 65.0
WLSH2_k127_8828775_29 Pkd domain containing protein - - - 0.0000001357 64.0
WLSH2_k127_8828775_3 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 619.0
WLSH2_k127_8828775_4 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 599.0
WLSH2_k127_8828775_5 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 492.0
WLSH2_k127_8828775_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 452.0
WLSH2_k127_8828775_7 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 421.0
WLSH2_k127_8828775_8 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 394.0
WLSH2_k127_8828775_9 NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K17994,K18007 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 359.0
WLSH2_k127_8842419_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 502.0
WLSH2_k127_8842419_1 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 424.0
WLSH2_k127_8842419_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000002268 222.0
WLSH2_k127_8842419_3 RIO1 family K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000003188 223.0
WLSH2_k127_8842419_4 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000000278 187.0
WLSH2_k127_8842419_5 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000003399 149.0
WLSH2_k127_8842419_6 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000000002828 111.0
WLSH2_k127_8842419_7 - - - - 0.00000000000000697 79.0
WLSH2_k127_8842831_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 410.0
WLSH2_k127_8842831_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
WLSH2_k127_8842831_2 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 295.0
WLSH2_k127_8842831_3 Peptidase family M28 K01439 - 3.5.1.18 0.00000000000000000000000000000000000001724 160.0
WLSH2_k127_8842831_4 asparaginyl-tRNA aminoacylation K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000003141 78.0
WLSH2_k127_9119747_0 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 486.0
WLSH2_k127_9119747_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000000000000000000000000000000002043 245.0
WLSH2_k127_9119747_2 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000006938 168.0
WLSH2_k127_9119747_3 membrane-associated protein domain - - - 0.000001881 57.0
WLSH2_k127_9119747_4 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00007723 49.0
WLSH2_k127_9119747_5 Protein of unknown function (DUF3198) - - - 0.0001335 49.0
WLSH2_k127_9160671_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 341.0
WLSH2_k127_9160671_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 326.0
WLSH2_k127_9160671_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000008492 100.0
WLSH2_k127_9160671_11 histone ubiquitination K10573 GO:0000151,GO:0000209,GO:0000228,GO:0000785,GO:0000790,GO:0000792,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006325,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016043,GO:0016567,GO:0016569,GO:0016570,GO:0016574,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0030163,GO:0031371,GO:0031625,GO:0031974,GO:0031981,GO:0032446,GO:0032991,GO:0033503,GO:0033554,GO:0034641,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051603,GO:0051716,GO:0061630,GO:0061659,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234 2.3.2.23 0.000000000005979 73.0
WLSH2_k127_9160671_12 to Saccharomyces cerevisiae RPN11 (YFR004W) K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.0000000001625 70.0
WLSH2_k127_9160671_13 cellulase activity K01387 - 3.4.24.3 0.0000004862 60.0
WLSH2_k127_9160671_2 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000006707 228.0
WLSH2_k127_9160671_3 SIS domain K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000001117 183.0
WLSH2_k127_9160671_4 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000714 175.0
WLSH2_k127_9160671_5 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000002025 163.0
WLSH2_k127_9160671_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000002396 149.0
WLSH2_k127_9160671_7 PFAM UBA THIF-type NAD FAD binding protein - - - 0.000000000000000000000000000000002721 140.0
WLSH2_k127_9160671_8 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000573 134.0
WLSH2_k127_9160671_9 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000007991 126.0
WLSH2_k127_9189211_0 Heat shock 70 kDa protein K04043 - - 7.129e-265 828.0
WLSH2_k127_9189211_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.219e-231 729.0
WLSH2_k127_9189211_10 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 319.0
WLSH2_k127_9189211_11 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 293.0
WLSH2_k127_9189211_12 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005542 278.0
WLSH2_k127_9189211_13 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000004659 268.0
WLSH2_k127_9189211_14 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000002355 269.0
WLSH2_k127_9189211_15 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000009037 239.0
WLSH2_k127_9189211_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000007951 237.0
WLSH2_k127_9189211_17 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000006006 227.0
WLSH2_k127_9189211_18 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000004985 223.0
WLSH2_k127_9189211_19 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000003347 214.0
WLSH2_k127_9189211_2 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 519.0
WLSH2_k127_9189211_20 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000004584 198.0
WLSH2_k127_9189211_21 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000008384 200.0
WLSH2_k127_9189211_22 - - - - 0.00000000000000000000000000000004172 136.0
WLSH2_k127_9189211_23 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000000000000000004451 128.0
WLSH2_k127_9189211_24 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.00000000000000000000000000001573 130.0
WLSH2_k127_9189211_25 Histidine kinase-like ATPases - - - 0.0000000000000000000000000004783 130.0
WLSH2_k127_9189211_26 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000001384 117.0
WLSH2_k127_9189211_27 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000004167 108.0
WLSH2_k127_9189211_28 protein conserved in archaea - - - 0.0000000000000000001569 94.0
WLSH2_k127_9189211_29 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000000000006382 83.0
WLSH2_k127_9189211_3 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 414.0
WLSH2_k127_9189211_30 - - - - 0.00000000122 63.0
WLSH2_k127_9189211_31 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00007821 53.0
WLSH2_k127_9189211_4 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 408.0
WLSH2_k127_9189211_5 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 385.0
WLSH2_k127_9189211_6 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 385.0
WLSH2_k127_9189211_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 375.0
WLSH2_k127_9189211_8 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 354.0
WLSH2_k127_9189211_9 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 325.0
WLSH2_k127_9592664_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 521.0
WLSH2_k127_9592664_1 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000641 266.0
WLSH2_k127_9592664_2 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.0000000000000000000000000000000000000000152 167.0
WLSH2_k127_9592664_3 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000002972 145.0
WLSH2_k127_9592664_4 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000002218 90.0
WLSH2_k127_9592664_5 Bacterial PH domain - - - 0.00000000002118 74.0
WLSH2_k127_9598434_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 611.0
WLSH2_k127_9598434_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 306.0
WLSH2_k127_9598434_10 Transcriptional regulator, ArsR family - - - 0.000000000000000000000000000000000004018 143.0
WLSH2_k127_9598434_11 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.00000000000000000000000000000000002714 144.0
WLSH2_k127_9598434_12 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.0000000000000000000000000000000003646 135.0
WLSH2_k127_9598434_13 NifU-like N terminal domain K04488 - - 0.0000000000000000000000004683 115.0
WLSH2_k127_9598434_14 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000001477 113.0
WLSH2_k127_9598434_15 Protein of unknown function DUF134 - - - 0.0000000000000000000007736 98.0
WLSH2_k127_9598434_16 DsrE/DsrF-like family - - - 0.0000000000000000004409 94.0
WLSH2_k127_9598434_17 Protein of unknown function DUF134 - - - 0.00000000239 62.0
WLSH2_k127_9598434_19 Bacterio-opsin activator HTH domain-containing protein - - - 0.000001165 58.0
WLSH2_k127_9598434_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003903 281.0
WLSH2_k127_9598434_3 CobQ CobB MinD ParA nucleotide binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
WLSH2_k127_9598434_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000003616 228.0
WLSH2_k127_9598434_5 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000007183 222.0
WLSH2_k127_9598434_6 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000004033 179.0
WLSH2_k127_9598434_7 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000003231 163.0
WLSH2_k127_9598434_8 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.00000000000000000000000000000000000005085 145.0
WLSH2_k127_9598434_9 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000008083 159.0
WLSH2_k127_9645300_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.582e-194 617.0
WLSH2_k127_9645300_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 589.0
WLSH2_k127_9645300_10 Protein of unknown function (DUF357) K09728 - - 0.000000000000000000000000000000000008897 140.0
WLSH2_k127_9645300_11 metal ion binding - - - 0.00000000000000000003649 96.0
WLSH2_k127_9645300_12 Aminotransferase class-III K00823 - 2.6.1.19 0.00000000000000000004994 92.0
WLSH2_k127_9645300_13 protein conserved in archaea K09723 - - 0.0000000000001346 79.0
WLSH2_k127_9645300_14 Transcriptional regulator K11924 - - 0.0000000000001459 74.0
WLSH2_k127_9645300_15 Belongs to the UPF0235 family K09131 - - 0.000000000003827 70.0
WLSH2_k127_9645300_16 Lrp/AsnC ligand binding domain - - - 0.0000001766 56.0
WLSH2_k127_9645300_2 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 539.0
WLSH2_k127_9645300_3 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 436.0
WLSH2_k127_9645300_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 336.0
WLSH2_k127_9645300_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000008805 260.0
WLSH2_k127_9645300_6 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000583 196.0
WLSH2_k127_9645300_7 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000002651 182.0
WLSH2_k127_9645300_8 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000001679 173.0
WLSH2_k127_9645300_9 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000007525 152.0
WLSH2_k127_9712310_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 480.0
WLSH2_k127_9712310_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 479.0
WLSH2_k127_9712310_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000003436 109.0
WLSH2_k127_9712310_11 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000000005824 106.0
WLSH2_k127_9712310_12 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000004336 100.0
WLSH2_k127_9712310_13 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000005172 77.0
WLSH2_k127_9712310_14 Major facilitator superfamily - - - 0.00001775 57.0
WLSH2_k127_9712310_15 Clostripain family - - - 0.00005419 51.0
WLSH2_k127_9712310_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 324.0
WLSH2_k127_9712310_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 309.0
WLSH2_k127_9712310_4 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 295.0
WLSH2_k127_9712310_5 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004584 270.0
WLSH2_k127_9712310_6 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 261.0
WLSH2_k127_9712310_7 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 259.0
WLSH2_k127_9712310_8 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000006147 218.0
WLSH2_k127_9712310_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003656 192.0
WLSH2_k127_9716672_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1405.0
WLSH2_k127_9716672_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 595.0
WLSH2_k127_9716672_10 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 368.0
WLSH2_k127_9716672_11 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 362.0
WLSH2_k127_9716672_12 PP-loop family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 321.0
WLSH2_k127_9716672_13 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 315.0
WLSH2_k127_9716672_14 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 314.0
WLSH2_k127_9716672_15 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 317.0
WLSH2_k127_9716672_16 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 324.0
WLSH2_k127_9716672_17 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 290.0
WLSH2_k127_9716672_18 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 308.0
WLSH2_k127_9716672_19 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008133 295.0
WLSH2_k127_9716672_2 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 574.0
WLSH2_k127_9716672_20 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006021 279.0
WLSH2_k127_9716672_21 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004658 272.0
WLSH2_k127_9716672_22 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000009333 271.0
WLSH2_k127_9716672_23 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000107 255.0
WLSH2_k127_9716672_24 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000003964 243.0
WLSH2_k127_9716672_25 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
WLSH2_k127_9716672_26 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.00000000000000000000000000000000000000000000000000000000000000000000009949 256.0
WLSH2_k127_9716672_27 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000006982 218.0
WLSH2_k127_9716672_28 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000003971 224.0
WLSH2_k127_9716672_29 PFAM DoxX family protein K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000000002936 195.0
WLSH2_k127_9716672_3 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 503.0
WLSH2_k127_9716672_30 B12 binding domain K14084 - - 0.00000000000000000000000000000000000000000000000000009432 194.0
WLSH2_k127_9716672_31 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.000000000000000000000000000000000000000000000000002375 197.0
WLSH2_k127_9716672_32 Belongs to the UPF0280 family K09740 - - 0.000000000000000000000000000000000000000000000000008151 189.0
WLSH2_k127_9716672_33 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000001878 178.0
WLSH2_k127_9716672_34 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.000000000000000000000000000000000000000000000002504 197.0
WLSH2_k127_9716672_35 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.0000000000000000000000000000000000000000000002747 171.0
WLSH2_k127_9716672_36 shikimate kinase activity K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000002614 173.0
WLSH2_k127_9716672_37 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000001092 162.0
WLSH2_k127_9716672_38 - - - - 0.00000000000000000000000000000000000000000552 165.0
WLSH2_k127_9716672_39 Glycine cleavage H-protein K02437 - - 0.00000000000000000000000000000000000000001407 158.0
WLSH2_k127_9716672_4 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 487.0
WLSH2_k127_9716672_40 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000001044 155.0
WLSH2_k127_9716672_41 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000000002137 152.0
WLSH2_k127_9716672_42 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000002394 151.0
WLSH2_k127_9716672_43 flavin reductase - - - 0.000000000000000000000000000000000000659 146.0
WLSH2_k127_9716672_44 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000004346 143.0
WLSH2_k127_9716672_45 PFAM NIL domain - - - 0.00000000000000000000000000000005272 128.0
WLSH2_k127_9716672_46 nucleotide metabolic process - - - 0.000000000000000000199 97.0
WLSH2_k127_9716672_47 pfam yhs - - - 0.0000000000000003489 82.0
WLSH2_k127_9716672_48 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0008150,GO:0009987,GO:0051301 - 0.000000000000007253 85.0
WLSH2_k127_9716672_49 helix_turn_helix ASNC type - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000001222 79.0
WLSH2_k127_9716672_5 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 405.0
WLSH2_k127_9716672_50 - - - - 0.000000009236 65.0
WLSH2_k127_9716672_6 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 389.0
WLSH2_k127_9716672_7 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 388.0
WLSH2_k127_9716672_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 408.0
WLSH2_k127_9716672_9 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 367.0
WLSH2_k127_9764956_0 4Fe-4S single cluster domain K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 565.0
WLSH2_k127_9764956_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 494.0
WLSH2_k127_9764956_10 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 306.0
WLSH2_k127_9764956_11 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 295.0
WLSH2_k127_9764956_12 ATP-grasp in the biosynthetic pathway with Ter operon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 292.0
WLSH2_k127_9764956_13 glutathione-regulated potassium exporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003488 284.0
WLSH2_k127_9764956_14 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004983 276.0
WLSH2_k127_9764956_15 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002212 280.0
WLSH2_k127_9764956_16 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007867 273.0
WLSH2_k127_9764956_17 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000003872 263.0
WLSH2_k127_9764956_18 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000002521 239.0
WLSH2_k127_9764956_19 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009469 235.0
WLSH2_k127_9764956_2 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 418.0
WLSH2_k127_9764956_20 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000001147 232.0
WLSH2_k127_9764956_21 Archaeal transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000005377 218.0
WLSH2_k127_9764956_22 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000002463 209.0
WLSH2_k127_9764956_23 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001217 200.0
WLSH2_k127_9764956_24 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000008053 212.0
WLSH2_k127_9764956_25 Lamin Tail Domain - - - 0.0000000000000000000000000000000000000000000000000002776 214.0
WLSH2_k127_9764956_26 PFAM glycosyl transferase group 1 K13677 - 2.4.1.208 0.00000000000000000000000000000000000000000000003996 183.0
WLSH2_k127_9764956_27 methanogen marker protein 4 - - - 0.0000000000000000000000000000000000000000000001573 177.0
WLSH2_k127_9764956_28 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000005432 172.0
WLSH2_k127_9764956_29 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000001299 170.0
WLSH2_k127_9764956_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 393.0
WLSH2_k127_9764956_30 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000005608 150.0
WLSH2_k127_9764956_32 PFAM polysaccharide biosynthesis protein - - - 0.00000000000000000000000000006419 133.0
WLSH2_k127_9764956_33 - - - - 0.0000000000000000000000001249 120.0
WLSH2_k127_9764956_34 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000001937 109.0
WLSH2_k127_9764956_35 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000000004668 96.0
WLSH2_k127_9764956_36 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000001591 96.0
WLSH2_k127_9764956_37 - - - - 0.000000000000000002329 89.0
WLSH2_k127_9764956_38 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.000000000000000002877 88.0
WLSH2_k127_9764956_39 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000005488 84.0
WLSH2_k127_9764956_4 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 389.0
WLSH2_k127_9764956_40 YjbR - - - 0.000000000000001054 81.0
WLSH2_k127_9764956_41 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000001939 79.0
WLSH2_k127_9764956_42 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.00000000000000441 78.0
WLSH2_k127_9764956_43 ACT domain protein - - - 0.0000000002561 66.0
WLSH2_k127_9764956_44 - - - - 0.000000002929 60.0
WLSH2_k127_9764956_45 - - - - 0.0000004286 57.0
WLSH2_k127_9764956_46 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00006191 55.0
WLSH2_k127_9764956_47 Acetyltransferase (GNAT) domain - - - 0.0004263 51.0
WLSH2_k127_9764956_48 EamA-like transporter family - - - 0.0008695 50.0
WLSH2_k127_9764956_5 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 390.0
WLSH2_k127_9764956_6 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 400.0
WLSH2_k127_9764956_7 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 376.0
WLSH2_k127_9764956_8 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 338.0
WLSH2_k127_9764956_9 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 335.0